|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10702 |
PRK10702 |
endonuclease III; Provisional |
6-213 |
1.43e-133 |
|
endonuclease III; Provisional
Pssm-ID: 182661 [Multi-domain] Cd Length: 211 Bit Score: 373.58 E-value: 1.43e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 6 MNKEKRHQILTRLRDDNPHPETELEYSSPFELLVAVTLSAQATDVGVNKATRKLFPVANTPQAILDLGHDTLRDYIKTIG 85
Cdd:PRK10702 1 MNKAKRLEILTRLRDNNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 86 LFNSKAANVYKMCQILVDEHNSIVPENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMGKDVVAVE 165
Cdd:PRK10702 81 LYNSKAENVIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 961462310 166 QKLEKVVPKEFKVDVHHWLILHGRYTCVARKPKCGSCIIEDLCEFKDK 213
Cdd:PRK10702 161 EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEK 208
|
|
| Nth |
COG0177 |
Endonuclease III [Replication, recombination and repair]; |
15-212 |
2.70e-119 |
|
Endonuclease III [Replication, recombination and repair];
Pssm-ID: 439947 [Multi-domain] Cd Length: 198 Bit Score: 336.68 E-value: 2.70e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 15 LTRLRDDNPHPETELEYSSPFELLVAVTLSAQATDVGVNKATRKLFPVANTPQAILDLGHDTLRDYIKTIGLFNSKAANV 94
Cdd:COG0177 1 LERLKELYPDAKTELDYRDPFELLVATILSAQTTDERVNKATPRLFARYPTPEALAAADLEELEELIRPIGLYRNKAKNI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 95 YKMCQILVDEHNSIVPENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMGKDVVAVEQKLEKVVPK 174
Cdd:COG0177 81 IALARILVEKYGGEVPETREELESLPGVGRKTANVVLNFAFGKPAIAVDTHVHRVSNRLGLVPGKDPEEVEKDLMKLIPK 160
|
170 180 190
....*....|....*....|....*....|....*...
gi 961462310 175 EFKVDVHHWLILHGRYTCVARKPKCGSCIIEDLCEFKD 212
Cdd:COG0177 161 EYWGDLHHLLILHGRYICKARKPKCEECPLADLCPYYG 198
|
|
| nth |
TIGR01083 |
endonuclease III; This equivalog model identifes nth members of the pfam00730 superfamily ... |
8-199 |
3.89e-112 |
|
endonuclease III; This equivalog model identifes nth members of the pfam00730 superfamily (HhH-GPD: Helix-hairpin-helix and Gly/Pro rich loop followed by a conserved aspartate). The major members of the superfamily are nth and mutY. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273434 [Multi-domain] Cd Length: 192 Bit Score: 318.56 E-value: 3.89e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 8 KEKRHQILTRLRDDNPHPETELEYSSPFELLVAVTLSAQATDVGVNKATRKLFPVANTPQAILDLGHDTLRDYIKTIGLF 87
Cdd:TIGR01083 1 RQKAQEILERLRKNYPHPTTELDFNNPFELLVATILSAQATDKRVNKATPKLFEVYPTPQALAQAGLEELEEYIKSIGLY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 88 NSKAANVYKMCQILVDEHNSIVPENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMGKDVVAVEQK 167
Cdd:TIGR01083 81 RNKAKNIIELCRKLVERYGGEVPEDREELVKLPGVGRKTANVVLNVAFGIPAIAVDTHVFRVSNRLGLSKGKDPIKVEED 160
|
170 180 190
....*....|....*....|....*....|..
gi 961462310 168 LEKVVPKEFKVDVHHWLILHGRYTCVARKPKC 199
Cdd:TIGR01083 161 LMKLVPREFWVKLHHWLILHGRYTCKARKPLC 192
|
|
| ENDO3c |
cd00056 |
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), ... |
35-188 |
6.43e-49 |
|
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
Pssm-ID: 238013 [Multi-domain] Cd Length: 158 Bit Score: 157.02 E-value: 6.43e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 35 FELLVAVTLSAQATDVGVNKATRKLFP-VANTPQAILDLGHDTLRDYIKTIGlFNSKAANVYKMCQILVDEHNSIV---P 110
Cdd:cd00056 1 FEVLVSEILSQQTTDKAVNKAYERLFErYGPTPEALAAADEEELRELIRSLG-YRRKAKYLKELARAIVEGFGGLVlddP 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 961462310 111 ENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKL-AMGKDVVAVEQKLEKVVPKEFKVDVHHWLILHG 188
Cdd:cd00056 80 DAREELLALPGVGRKTANVVLLFALGPDAFPVDTHVRRVLKRLGLiPKKKTPEELEELLEELLPKPYWGEANQALMDLG 158
|
|
| ENDO3c |
smart00478 |
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), ... |
43-190 |
5.92e-48 |
|
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
Pssm-ID: 214684 [Multi-domain] Cd Length: 149 Bit Score: 154.34 E-value: 5.92e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 43 LSAQATDVGVNKATRKLFPVANTPQAILDLGHDTLRDYIKTIGLFNSKAANVYKMCQILVDEHNSIVPENREALEALPGV 122
Cdd:smart00478 1 LSQQTTDERVNKATERLFEKFPTPEDLAAADEEELEELIRGLGFYRRKARYLIELARILVEEYGGEVPDDREELLKLPGV 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 961462310 123 GRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMGKDV-VAVEQKLEKVVPKEFKVDVHHWLILHGRY 190
Cdd:smart00478 81 GRKTANAVLSFALGKPFIPVDTHVLRIAKRLGLVDKKSTpEEVEKLLEKLLPEEDWRELNLLLIDFGRT 149
|
|
| HhH-GPD |
pfam00730 |
HhH-GPD superfamily base excision DNA repair protein; This family contains a diverse range of ... |
39-174 |
7.01e-36 |
|
HhH-GPD superfamily base excision DNA repair protein; This family contains a diverse range of structurally related DNA repair proteins. The superfamily is called the HhH-GPD family after its hallmark Helix-hairpin-helix and Gly/Pro rich loop followed by a conserved aspartate. This includes endonuclease III, EC:4.2.99.18 and MutY an A/G-specific adenine glycosylase, both have a C terminal 4Fe-4S cluster. The family also includes 8-oxoguanine DNA glycosylases. The methyl-CPG binding protein MBD4 also contains a related domain that is a thymine DNA glycosylase. The family also includes DNA-3-methyladenine glycosylase II EC:3.2.2.21 and other members of the AlkA family.
Pssm-ID: 425841 [Multi-domain] Cd Length: 141 Bit Score: 123.16 E-value: 7.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 39 VAVTLSAQATDVGVNKATRKLF-PVANTPQAILDLGHDTLRDYIKTIGLFNSKAANVYKMCQILVDEHNSIVPENREALE 117
Cdd:pfam00730 1 VSAILSQQTSDKAVNKITERLFeKFFPTPEDLADADEEELRELIRGLGFYRRKAKYLKELARILVEGYGGEVPLDEEELE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 961462310 118 A-LPGVGRKTANVVLNTAFG--WPVIAVDTHIFRVSNRTKLAMGKD-VVAVEQKLEKVVPK 174
Cdd:pfam00730 81 AlLKGVGRWTAEAVLIFALGrpDPLPVVDTHVRRVLKRLGLIKEKPtPKEVERELEELWPP 141
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10702 |
PRK10702 |
endonuclease III; Provisional |
6-213 |
1.43e-133 |
|
endonuclease III; Provisional
Pssm-ID: 182661 [Multi-domain] Cd Length: 211 Bit Score: 373.58 E-value: 1.43e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 6 MNKEKRHQILTRLRDDNPHPETELEYSSPFELLVAVTLSAQATDVGVNKATRKLFPVANTPQAILDLGHDTLRDYIKTIG 85
Cdd:PRK10702 1 MNKAKRLEILTRLRDNNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 86 LFNSKAANVYKMCQILVDEHNSIVPENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMGKDVVAVE 165
Cdd:PRK10702 81 LYNSKAENVIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 961462310 166 QKLEKVVPKEFKVDVHHWLILHGRYTCVARKPKCGSCIIEDLCEFKDK 213
Cdd:PRK10702 161 EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEK 208
|
|
| Nth |
COG0177 |
Endonuclease III [Replication, recombination and repair]; |
15-212 |
2.70e-119 |
|
Endonuclease III [Replication, recombination and repair];
Pssm-ID: 439947 [Multi-domain] Cd Length: 198 Bit Score: 336.68 E-value: 2.70e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 15 LTRLRDDNPHPETELEYSSPFELLVAVTLSAQATDVGVNKATRKLFPVANTPQAILDLGHDTLRDYIKTIGLFNSKAANV 94
Cdd:COG0177 1 LERLKELYPDAKTELDYRDPFELLVATILSAQTTDERVNKATPRLFARYPTPEALAAADLEELEELIRPIGLYRNKAKNI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 95 YKMCQILVDEHNSIVPENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMGKDVVAVEQKLEKVVPK 174
Cdd:COG0177 81 IALARILVEKYGGEVPETREELESLPGVGRKTANVVLNFAFGKPAIAVDTHVHRVSNRLGLVPGKDPEEVEKDLMKLIPK 160
|
170 180 190
....*....|....*....|....*....|....*...
gi 961462310 175 EFKVDVHHWLILHGRYTCVARKPKCGSCIIEDLCEFKD 212
Cdd:COG0177 161 EYWGDLHHLLILHGRYICKARKPKCEECPLADLCPYYG 198
|
|
| nth |
TIGR01083 |
endonuclease III; This equivalog model identifes nth members of the pfam00730 superfamily ... |
8-199 |
3.89e-112 |
|
endonuclease III; This equivalog model identifes nth members of the pfam00730 superfamily (HhH-GPD: Helix-hairpin-helix and Gly/Pro rich loop followed by a conserved aspartate). The major members of the superfamily are nth and mutY. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273434 [Multi-domain] Cd Length: 192 Bit Score: 318.56 E-value: 3.89e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 8 KEKRHQILTRLRDDNPHPETELEYSSPFELLVAVTLSAQATDVGVNKATRKLFPVANTPQAILDLGHDTLRDYIKTIGLF 87
Cdd:TIGR01083 1 RQKAQEILERLRKNYPHPTTELDFNNPFELLVATILSAQATDKRVNKATPKLFEVYPTPQALAQAGLEELEEYIKSIGLY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 88 NSKAANVYKMCQILVDEHNSIVPENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMGKDVVAVEQK 167
Cdd:TIGR01083 81 RNKAKNIIELCRKLVERYGGEVPEDREELVKLPGVGRKTANVVLNVAFGIPAIAVDTHVFRVSNRLGLSKGKDPIKVEED 160
|
170 180 190
....*....|....*....|....*....|..
gi 961462310 168 LEKVVPKEFKVDVHHWLILHGRYTCVARKPKC 199
Cdd:TIGR01083 161 LMKLVPREFWVKLHHWLILHGRYTCKARKPLC 192
|
|
| ENDO3c |
cd00056 |
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), ... |
35-188 |
6.43e-49 |
|
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
Pssm-ID: 238013 [Multi-domain] Cd Length: 158 Bit Score: 157.02 E-value: 6.43e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 35 FELLVAVTLSAQATDVGVNKATRKLFP-VANTPQAILDLGHDTLRDYIKTIGlFNSKAANVYKMCQILVDEHNSIV---P 110
Cdd:cd00056 1 FEVLVSEILSQQTTDKAVNKAYERLFErYGPTPEALAAADEEELRELIRSLG-YRRKAKYLKELARAIVEGFGGLVlddP 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 961462310 111 ENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKL-AMGKDVVAVEQKLEKVVPKEFKVDVHHWLILHG 188
Cdd:cd00056 80 DAREELLALPGVGRKTANVVLLFALGPDAFPVDTHVRRVLKRLGLiPKKKTPEELEELLEELLPKPYWGEANQALMDLG 158
|
|
| ENDO3c |
smart00478 |
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), ... |
43-190 |
5.92e-48 |
|
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
Pssm-ID: 214684 [Multi-domain] Cd Length: 149 Bit Score: 154.34 E-value: 5.92e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 43 LSAQATDVGVNKATRKLFPVANTPQAILDLGHDTLRDYIKTIGLFNSKAANVYKMCQILVDEHNSIVPENREALEALPGV 122
Cdd:smart00478 1 LSQQTTDERVNKATERLFEKFPTPEDLAAADEEELEELIRGLGFYRRKARYLIELARILVEEYGGEVPDDREELLKLPGV 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 961462310 123 GRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMGKDV-VAVEQKLEKVVPKEFKVDVHHWLILHGRY 190
Cdd:smart00478 81 GRKTANAVLSFALGKPFIPVDTHVLRIAKRLGLVDKKSTpEEVEKLLEKLLPEEDWRELNLLLIDFGRT 149
|
|
| HhH-GPD |
pfam00730 |
HhH-GPD superfamily base excision DNA repair protein; This family contains a diverse range of ... |
39-174 |
7.01e-36 |
|
HhH-GPD superfamily base excision DNA repair protein; This family contains a diverse range of structurally related DNA repair proteins. The superfamily is called the HhH-GPD family after its hallmark Helix-hairpin-helix and Gly/Pro rich loop followed by a conserved aspartate. This includes endonuclease III, EC:4.2.99.18 and MutY an A/G-specific adenine glycosylase, both have a C terminal 4Fe-4S cluster. The family also includes 8-oxoguanine DNA glycosylases. The methyl-CPG binding protein MBD4 also contains a related domain that is a thymine DNA glycosylase. The family also includes DNA-3-methyladenine glycosylase II EC:3.2.2.21 and other members of the AlkA family.
Pssm-ID: 425841 [Multi-domain] Cd Length: 141 Bit Score: 123.16 E-value: 7.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 39 VAVTLSAQATDVGVNKATRKLF-PVANTPQAILDLGHDTLRDYIKTIGLFNSKAANVYKMCQILVDEHNSIVPENREALE 117
Cdd:pfam00730 1 VSAILSQQTSDKAVNKITERLFeKFFPTPEDLADADEEELRELIRGLGFYRRKAKYLKELARILVEGYGGEVPLDEEELE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 961462310 118 A-LPGVGRKTANVVLNTAFG--WPVIAVDTHIFRVSNRTKLAMGKD-VVAVEQKLEKVVPK 174
Cdd:pfam00730 81 AlLKGVGRWTAEAVLIFALGrpDPLPVVDTHVRRVLKRLGLIKEKPtPKEVERELEELWPP 141
|
|
| MutY |
COG1194 |
Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and ... |
90-216 |
5.40e-14 |
|
Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair];
Pssm-ID: 440807 [Multi-domain] Cd Length: 350 Bit Score: 69.40 E-value: 5.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 90 KAAnvykmcQILVDEHNSIVPENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNR-----TKLAMGKDVVAV 164
Cdd:COG1194 90 KAA------QQVVEEHGGVFPDTYEELLALPGIGPYTAAAIASIAFGEPAPIVDGNVKRVLSRlfaieGPIGSPAAKKEL 163
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 961462310 165 EQKLEKVVPKEfkvDVhhwlilhGRYT----------CVARKPKCGSCIIEDLCE-FKDKTEE 216
Cdd:COG1194 164 WALAEELLPPE---RP-------GDFNqalmdlgatvCTPKKPKCLLCPLQDDCAaFAEGRQE 216
|
|
| PRK10880 |
PRK10880 |
adenine DNA glycosylase; |
89-208 |
4.25e-10 |
|
adenine DNA glycosylase;
Pssm-ID: 182805 [Multi-domain] Cd Length: 350 Bit Score: 58.18 E-value: 4.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 89 SKAANVYKMCQILVDEHNSIVPENREALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFRVSNRTKLAMG----KDvvaV 164
Cdd:PRK10880 84 ARARNLHKAAQQVATLHGGEFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGwpgkKE---V 160
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 961462310 165 EQKL----EKVVPKEFKVDVHHWLILHGRYTCVARKPKCGSCIIEDLC 208
Cdd:PRK10880 161 ENRLwqlsEQVTPAVGVERFNQAMMDLGAMVCTRSKPKCELCPLQNGC 208
|
|
| AlkA |
COG0122 |
3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [Replication, recombination and ... |
10-146 |
2.24e-08 |
|
3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [Replication, recombination and repair];
Pssm-ID: 439892 [Multi-domain] Cd Length: 255 Bit Score: 52.58 E-value: 2.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 10 KRHQILTRLRDDNPHPETELEySSPFELLVAVTLSAQ-----------------ATDVGVNKATRKLFPvanTPQAILDL 72
Cdd:COG0122 61 ARDPVLAPLIERYPGLRLPRR-PDPFEALVRAILGQQvsvaaartiwrrlvalfGEPIEGPGGGLYAFP---TPEALAAA 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 73 GHDTLRDyiktIGLFNSKAANVYKMCQILVDehNSIVPEN---------REALEALPGVGRKTANVVLNTAFGWP--VIA 141
Cdd:COG0122 137 SEEELRA----CGLSRRKARYLRALARAVAD--GELDLEAlaglddeeaIARLTALPGIGPWTAEMVLLFALGRPdaFPA 210
|
....*
gi 961462310 142 VDTHI 146
Cdd:COG0122 211 GDLGL 215
|
|
| PRK13910 |
PRK13910 |
DNA glycosylase MutY; Provisional |
57-216 |
1.09e-07 |
|
DNA glycosylase MutY; Provisional
Pssm-ID: 172427 [Multi-domain] Cd Length: 289 Bit Score: 51.18 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 57 RKLFPVANTPQAILDLGHDTLRDYI---KTIGLFnSKAANVYKMCQILVDEHNSIVPENREALEALPGVGRKTANVVLNT 133
Cdd:PRK13910 13 RFYSPFLEAFPTLKDLANAPLEEVLllwRGLGYY-SRAKNLKKSAEICVKEHHSQLPNDYQSLLKLPGIGAYTANAILCF 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 134 AFGWPVIAVDTHIFRVSNRTkLAMGKDVVA--VEQKLEKVVPKEFKVDVHHWLILHGRYTCvARKPKCGSCIIEDLCEFK 211
Cdd:PRK13910 92 GFREKSACVDANIKRVLLRL-FGLDPNIHAkdLQIKANDFLNLNESFNHNQALIDLGALIC-SPKPKCAICPLNPYCLGK 169
|
....*
gi 961462310 212 DKTEE 216
Cdd:PRK13910 170 NNPEK 174
|
|
| HHH |
pfam00633 |
Helix-hairpin-helix motif; The helix-hairpin-helix DNA-binding motif is found to be duplicated ... |
104-131 |
2.67e-06 |
|
Helix-hairpin-helix motif; The helix-hairpin-helix DNA-binding motif is found to be duplicated in the central domain of RuvA. The HhH domain of DisA, a bacterial checkpoint control protein, is a DNA-binding domain.
Pssm-ID: 425789 [Multi-domain] Cd Length: 30 Bit Score: 42.79 E-value: 2.67e-06
10 20
....*....|....*....|....*...
gi 961462310 104 EHNSIVPENREALEALPGVGRKTANVVL 131
Cdd:pfam00633 1 SLEGLIPASVEELLALPGVGPKTAEAIL 28
|
|
| FES |
smart00525 |
iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); ... |
191-211 |
4.40e-05 |
|
iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3);
Pssm-ID: 197771 [Multi-domain] Cd Length: 21 Bit Score: 39.07 E-value: 4.40e-05
|
| EndIII_4Fe-2S |
pfam10576 |
Iron-sulfur binding domain of endonuclease III; Escherichia coli endonuclease III (EC 4.2.99. ... |
192-208 |
1.33e-04 |
|
Iron-sulfur binding domain of endonuclease III; Escherichia coli endonuclease III (EC 4.2.99.18) is a DNA repair enzyme that acts both as a DNA N-glycosylase, removing oxidized pyrimidines from DNA, and as an apurinic/apyrimidinic (AP) endonuclease, introducing a single-strand nick at the site from which the damaged base was removed. Endonuclease III is an iron-sulfur protein that binds a single 4Fe-4S cluster. The 4Fe-4S cluster does not seem to be important for catalytic activity, but is probably involved in the proper positioning of the enzyme along the DNA strand. The 4Fe-4S cluster is bound by four cysteines which are all located in a 17 amino acid region at the C-terminal end of endonuclease III. A similar region is also present in the central section of mutY and in the C-terminus of ORF-10 and of the Micro-coccus UV endonuclease.
Pssm-ID: 463153 [Multi-domain] Cd Length: 17 Bit Score: 37.75 E-value: 1.33e-04
|
| PRK13913 |
PRK13913 |
3-methyladenine DNA glycosylase; Provisional |
35-148 |
4.91e-04 |
|
3-methyladenine DNA glycosylase; Provisional
Pssm-ID: 184390 Cd Length: 218 Bit Score: 39.83 E-value: 4.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961462310 35 FELLVAVTLSAQATDVGVNKAT---RKLFPVANTPQAIL-DLGH---DTLRDYIKTIGLFNSKAANVYKMCQILVDEHNS 107
Cdd:PRK13913 31 FEALLGAVLTQNTKFEAVEKSLenlKNAFILENDDEINLkKIAYiefSKLAECVRPSGFYNQKAKRLIDLSENILKDFGS 110
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 961462310 108 I--VPEN--REALEALPGVGRKTANVVLNTAFGWPVIAVDTHIFR 148
Cdd:PRK13913 111 FenFKQEvtREWLLDQKGIGKESADAILCYVCAKEVMVVDKYSYL 155
|
|
| ogg |
TIGR00588 |
8-oxoguanine DNA-glycosylase (ogg); All proteins in this family for which functions are known ... |
111-152 |
2.30e-03 |
|
8-oxoguanine DNA-glycosylase (ogg); All proteins in this family for which functions are known are 8-oxo-guanaine DNA glycosylases that function in base excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). This family is distantly realted to the Nth-MutY superfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 211589 [Multi-domain] Cd Length: 310 Bit Score: 38.35 E-value: 2.30e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 961462310 111 ENREALEALPGVGRKTANVVLNTAFGWP-VIAVDTHIFRVSNR 152
Cdd:TIGR00588 217 DAREALCELPGVGPKVADCICLMGLDKPqAVPVDVHVWRIANR 259
|
|
| |
