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Conserved domains on  [gi|914399211|gb|AKV66880|]
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hypothetical protein VL20_1734 [Microcystis panniformis FACHB-1757]

Protein Classification

AAA family ATPase( domain architecture ID 11468604)

AAA family ATPase containing an AAA (ATPases Associated with various cellular Activities) domain, may function as an ATP-dependent endonuclease or the ATPase component of an ABC-type transporter

Gene Ontology:  GO:0005524|GO:0016887
PubMed:  16828312|15037233|15037234|18208389|18466635

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4637 COG4637
Predicted ATPase [General function prediction only];
8-389 1.62e-123

Predicted ATPase [General function prediction only];


:

Pssm-ID: 443675 [Multi-domain]  Cd Length: 371  Bit Score: 361.56  E-value: 1.62e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   8 RIENLRVQNYRALQDLELKsIAPLTVFLGPNGSGKSTIFDVFAFLSECFTVGLKKAWDKRGRFKELRTRGQEGY---III 84
Cdd:COG4637    1 MITRIRIKNFKSLRDLELP-LGPLTVLIGANGSGKSNLLDALRFLSDAARGGLQDALARRGGLEELLWRGPRTItepIRL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  85 ELKYREKfASPLITYHLAIN--EANNRPYVAEEWLQWRQGARGKPyrFLNFKEgEGIVISGENpqeederiyERLDSPEf 162
Cdd:COG4637   80 ELEFAEE-DERDLRYELELGlpEPGGRPEVKEERLWLKRGSGGRP--FLDFRP-KGRAVGGEP---------ERLDSPE- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 163 LAVSTLGQLAKHPRVSALRRFITSWYLSYLTADNTRTQPEAGAQERLSPTGDNLPNVIQYLKEDHPQRLESILQTLSRRI 242
Cdd:COG4637  146 SLLSQLGDPERFPELRALREALRSWRFYDFHPAPLRQPQPAGRTPVLAPDGSNLAAVLATLRETHPERFERILEALRDAF 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 243 PRLEKVEASIMPNGQLLLQIKDAPFQEPILSKFASDGTLKMLAYLTILYDPSPPQVLGIEEPENHLHPRLLPELAEECRA 322
Cdd:COG4637  226 PGFEDIEVEPDEDGRVLLEFREKGLDRPFPARELSDGTLRFLALLAALLSPRPPPLLCIEEPENGLHPDLLPALAELLRE 305

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 914399211 323 ATASTQLMVTTHSPFFVDGLKPDEVWVLYRDENGFTQAKRTSAMQgVKEFIqNGALLGQLWMEDYFD 389
Cdd:COG4637  306 ASERTQVIVTTHSPALLDALEPEEVLVLEREDDGETRIRRLSDLE-LPEWL-EGYSLGELWARGLLG 370
 
Name Accession Description Interval E-value
COG4637 COG4637
Predicted ATPase [General function prediction only];
8-389 1.62e-123

Predicted ATPase [General function prediction only];


Pssm-ID: 443675 [Multi-domain]  Cd Length: 371  Bit Score: 361.56  E-value: 1.62e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   8 RIENLRVQNYRALQDLELKsIAPLTVFLGPNGSGKSTIFDVFAFLSECFTVGLKKAWDKRGRFKELRTRGQEGY---III 84
Cdd:COG4637    1 MITRIRIKNFKSLRDLELP-LGPLTVLIGANGSGKSNLLDALRFLSDAARGGLQDALARRGGLEELLWRGPRTItepIRL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  85 ELKYREKfASPLITYHLAIN--EANNRPYVAEEWLQWRQGARGKPyrFLNFKEgEGIVISGENpqeederiyERLDSPEf 162
Cdd:COG4637   80 ELEFAEE-DERDLRYELELGlpEPGGRPEVKEERLWLKRGSGGRP--FLDFRP-KGRAVGGEP---------ERLDSPE- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 163 LAVSTLGQLAKHPRVSALRRFITSWYLSYLTADNTRTQPEAGAQERLSPTGDNLPNVIQYLKEDHPQRLESILQTLSRRI 242
Cdd:COG4637  146 SLLSQLGDPERFPELRALREALRSWRFYDFHPAPLRQPQPAGRTPVLAPDGSNLAAVLATLRETHPERFERILEALRDAF 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 243 PRLEKVEASIMPNGQLLLQIKDAPFQEPILSKFASDGTLKMLAYLTILYDPSPPQVLGIEEPENHLHPRLLPELAEECRA 322
Cdd:COG4637  226 PGFEDIEVEPDEDGRVLLEFREKGLDRPFPARELSDGTLRFLALLAALLSPRPPPLLCIEEPENGLHPDLLPALAELLRE 305

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 914399211 323 ATASTQLMVTTHSPFFVDGLKPDEVWVLYRDENGFTQAKRTSAMQgVKEFIqNGALLGQLWMEDYFD 389
Cdd:COG4637  306 ASERTQVIVTTHSPALLDALEPEEVLVLEREDDGETRIRRLSDLE-LPEWL-EGYSLGELWARGLLG 370
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 31-340 1.03e-27

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 110.94  E-value: 1.03e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   31 LTVFLGPNGSGKSTIFDVFAFLSECFTV--GLKKAWDKRGRFKELRTRGQEGYIIIELKYR-EKFASPLITYHLAINeaN 107
Cdd:pfam13304   1 INVLIGPNGSGKSNLLEALRFLADFDALviGLTDERSRNGGIGGIPSLLNGIDPKEPIEFEiSEFLEDGVRYRYGLD--L 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  108 NRPYVAEEWLQWRQGARGKPYRFLNFKEGEGIVIsgenPQEEDERIYERLDSPEFLAVSTLGQLAKHPRVSALRRFITSW 187
Cdd:pfam13304  79 EREDVEEKLSSKPTLLEKRLLLREDSEEREPKFP----PEAEELRLGLDVEERIELSLSELSDLISGLLLLSIISPLSFL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  188 YLSYLTADNTRTQPEAGAQERLspTGDNLPNVIQYLkEDHPQRLESILQTLSRRIPRLEKVEASIMPNGQLLLQIKDApf 267
Cdd:pfam13304 155 LLLDEGLLLEDWAVLDLAADLA--LFPDLKELLQRL-VRGLKLADLNLSDLGEGIEKSLLVDDRLRERGLILLENGGG-- 229

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 914399211  268 qEPILSKFASDGTLKMLAYLTILY-DPSPPQVLGIEEPENHLHPRLLPELAEE-CRAATASTQLMVTTHSPFFVD 340
Cdd:pfam13304 230 -GELPAFELSDGTKRLLALLAALLsALPKGGLLLIDEPESGLHPKLLRRLLELlKELSRNGAQLILTTHSPLLLD 303
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 8-52 1.09e-04

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 42.23  E-value: 1.09e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 914399211   8 RIENLRV--QNYRALQDLELKsIAP--LTVFLGPNGSGKSTIFDVFAFL 52
Cdd:cd00267    1 EIENLSFryGGRTALDNVSLT-LKAgeIVALVGPNGSGKSTLLRAIAGL 48
recF PRK00064
recombination protein F; Reviewed
 8-45 1.30e-04

recombination protein F; Reviewed


Pssm-ID: 234608 [Multi-domain]  Cd Length: 361  Bit Score: 43.61  E-value: 1.30e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 914399211   8 RIENLRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTI 45
Cdd:PRK00064   2 YLTRLSLTDFRNYEELDLELSPGVNVLVGENGQGKTNL 39
restrict_AAA_1 TIGR04435
restriction system-associated AAA family ATPase; Members of this family are AAA family ATPases ...
 268-362 6.62e-04

restriction system-associated AAA family ATPase; Members of this family are AAA family ATPases by homology. They occur regularly in a conserved gene neighborhood with the restriction (R), modification (M), and specificity (S) proteins of an apparent type I restriction enzyme system, plus one additional uncharacterized protein. It is not clear whether members of this family contribute to restriction per se, or to another process such as transfer of mobile elements.


Pssm-ID: 275228 [Multi-domain]  Cd Length: 555  Bit Score: 41.57  E-value: 6.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  268 QEPILSKFASDGTLKMLAYL-TILYDPSPPQVLGIEEPENHLHP--------RLLPELAEECRAAtASTQLMVTTHSPFF 338
Cdd:TIGR04435 378 EKPVLLKSLSDGEHQLLHSLgLCLLFKDTNSLFLLDEPETHFNPkwrasfisRLRQCLEAGNTKN-VMQEMLITTHSPFL 456

                          90       100
                  ....*....|....*....|....*
gi 914399211  339 VDGLKPDEVWVLYRD-ENGFTQAKR 362
Cdd:TIGR04435 457 ISDCKPENVLVFKKNkENGKVEISL 481
 
Name Accession Description Interval E-value
COG4637 COG4637
Predicted ATPase [General function prediction only];
8-389 1.62e-123

Predicted ATPase [General function prediction only];


Pssm-ID: 443675 [Multi-domain]  Cd Length: 371  Bit Score: 361.56  E-value: 1.62e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   8 RIENLRVQNYRALQDLELKsIAPLTVFLGPNGSGKSTIFDVFAFLSECFTVGLKKAWDKRGRFKELRTRGQEGY---III 84
Cdd:COG4637    1 MITRIRIKNFKSLRDLELP-LGPLTVLIGANGSGKSNLLDALRFLSDAARGGLQDALARRGGLEELLWRGPRTItepIRL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  85 ELKYREKfASPLITYHLAIN--EANNRPYVAEEWLQWRQGARGKPyrFLNFKEgEGIVISGENpqeederiyERLDSPEf 162
Cdd:COG4637   80 ELEFAEE-DERDLRYELELGlpEPGGRPEVKEERLWLKRGSGGRP--FLDFRP-KGRAVGGEP---------ERLDSPE- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 163 LAVSTLGQLAKHPRVSALRRFITSWYLSYLTADNTRTQPEAGAQERLSPTGDNLPNVIQYLKEDHPQRLESILQTLSRRI 242
Cdd:COG4637  146 SLLSQLGDPERFPELRALREALRSWRFYDFHPAPLRQPQPAGRTPVLAPDGSNLAAVLATLRETHPERFERILEALRDAF 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 243 PRLEKVEASIMPNGQLLLQIKDAPFQEPILSKFASDGTLKMLAYLTILYDPSPPQVLGIEEPENHLHPRLLPELAEECRA 322
Cdd:COG4637  226 PGFEDIEVEPDEDGRVLLEFREKGLDRPFPARELSDGTLRFLALLAALLSPRPPPLLCIEEPENGLHPDLLPALAELLRE 305

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 914399211 323 ATASTQLMVTTHSPFFVDGLKPDEVWVLYRDENGFTQAKRTSAMQgVKEFIqNGALLGQLWMEDYFD 389
Cdd:COG4637  306 ASERTQVIVTTHSPALLDALEPEEVLVLEREDDGETRIRRLSDLE-LPEWL-EGYSLGELWARGLLG 370
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 31-340 1.03e-27

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 110.94  E-value: 1.03e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   31 LTVFLGPNGSGKSTIFDVFAFLSECFTV--GLKKAWDKRGRFKELRTRGQEGYIIIELKYR-EKFASPLITYHLAINeaN 107
Cdd:pfam13304   1 INVLIGPNGSGKSNLLEALRFLADFDALviGLTDERSRNGGIGGIPSLLNGIDPKEPIEFEiSEFLEDGVRYRYGLD--L 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  108 NRPYVAEEWLQWRQGARGKPYRFLNFKEGEGIVIsgenPQEEDERIYERLDSPEFLAVSTLGQLAKHPRVSALRRFITSW 187
Cdd:pfam13304  79 EREDVEEKLSSKPTLLEKRLLLREDSEEREPKFP----PEAEELRLGLDVEERIELSLSELSDLISGLLLLSIISPLSFL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  188 YLSYLTADNTRTQPEAGAQERLspTGDNLPNVIQYLkEDHPQRLESILQTLSRRIPRLEKVEASIMPNGQLLLQIKDApf 267
Cdd:pfam13304 155 LLLDEGLLLEDWAVLDLAADLA--LFPDLKELLQRL-VRGLKLADLNLSDLGEGIEKSLLVDDRLRERGLILLENGGG-- 229

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 914399211  268 qEPILSKFASDGTLKMLAYLTILY-DPSPPQVLGIEEPENHLHPRLLPELAEE-CRAATASTQLMVTTHSPFFVD 340
Cdd:pfam13304 230 -GELPAFELSDGTKRLLALLAALLsALPKGGLLLIDEPESGLHPKLLRRLLELlKELSRNGAQLILTTHSPLLLD 303
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
8-354 3.69e-22

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 95.06  E-value: 3.69e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   8 RIENLRVQNYRALQDLE--LKSIAPLTVFLGPNGSGKSTIFDVFAFLSECFTVGLKKAWDKRgrfkelrtrgqegyiiIE 85
Cdd:COG3950    2 RIKSLTIENFRGFEDLEidFDNPPRLTVLVGENGSGKTTLLEAIALALSGLLSRLDDVKFRK----------------LL 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  86 LKYREKFA-SPLITYhlaineannrpYvaeewlqwrqgargKPYRFLNfkegegivisgENPQEEDERIYERLDSPEFLA 164
Cdd:COG3950   66 IRNGEFGDsAKLILY-----------Y--------------GTSRLLL-----------DGPLKKLERLKEEYFSRLDGY 109

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 165 VSTLGQLAKhprvsaLRRFItSWYLSYLTadntrtqpeagaqerlsptgdnlpNVIQYLKEDHPQRLESILQTLSRRIPR 244
Cdd:COG3950  110 DSLLDEDSN------LREFL-EWLREYLE------------------------DLENKLSDELDEKLEAVREALNKLLPD 158

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 245 LEKVEASIMPNGQLLLQIKDAPFqePILSkfASDG---TLKM---LAYLTILYDPSPPQVLG------IEEPENHLHP-- 310
Cdd:COG3950  159 FKDIRIDRDPGRLVILDKNGEEL--PLNQ--LSDGersLLALvgdLARRLAELNPALENPLEgegivlIDEIDLHLHPkw 234

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 914399211 311 --RLLPELaeecRAATASTQLMVTTHSPFFVDGLKPDEVWVLYRDE 354
Cdd:COG3950  235 qrRILPDL----RKIFPNIQFIVTTHSPLILSSLEDEEVIVLERDE 276
COG1106 COG1106
ATPase/GTPase, AAA15 family [General function prediction only];
9-356 7.09e-21

ATPase/GTPase, AAA15 family [General function prediction only];


Pssm-ID: 440723 [Multi-domain]  Cd Length: 330  Bit Score: 92.41  E-value: 7.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   9 IENLRVQNYRALQD-LELKSIA------PLTVFLGPNGSGKSTIFDVFAFLSECFTVGLKKAWDKRGRFKELRTRGQEGY 81
Cdd:COG1106    2 LISFSIENFRSFKDeLTLSMVAsglrllRVNLIYGANASGKSNLLEALYFLRNLVLNSSQPGDKLVEPFLLDSESKNEPS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  82 II-IELKYREKfaspLITYHLAINEANnrpyVAEEWLqwrqgargkpyrflnfkegegivisgenpqeederiyerldsp 160
Cdd:COG1106   82 EFeILFLLDGV----RYEYGFELDKER----IISEWL------------------------------------------- 110

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 161 EFLavSTLGQLaKHPRVSALRRFITSwylsyltadntrtqpeagaQERLSPTGDNLPNVIQYlKEDHPQRLESILQTLSR 240
Cdd:COG1106  111 YFL--STAAQL-NVPLLSPLYDWFDN-------------------NISLDTSSDGLTLLLKE-DESLKEELLELLKIADP 167

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 241 RIPRLEKVEASIMPNGQLLLQIKDAPFQEPILSKFASDGTLKMLAYLTILYDPSP-PQVLGIEEPENHLHPRLLPELAEE 319
Cdd:COG1106  168 GIEDIEVEEEEIEDLVERKLIFKHKGGNVPLPLSEESDGTKRLLALAGALLDALAkGGVLLIDEIEASLHPSLLRKLLKL 247

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 914399211 320 CRAATAS--TQLMVTTHSPFFVDG----LKPDEVWVLYRDENG 356
Cdd:COG1106  248 FLDLANKnnAQLIFTTHSTELLDAflelLRRDQIWFVEKDKDG 290
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
 8-375 7.87e-18

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 83.90  E-value: 7.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   8 RIENLRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTIFDVFAFLsecftvgLKKAWDKRGRFKELRTRGQEGYIIIELK 87
Cdd:COG3593    2 KLEKIKIKNFRSIKDLSIELSDDLTVLVGENNSGKSSILEALRLL-------LGPSSSRKFDEEDFYLGDDPDLPEIEIE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  88 YRekFASPLityhlaineannrpyvaeewlqwrqgargkpYRFLNFkegegivISGENPQEEDERIYERLDSpeflavst 167
Cdd:COG3593   75 LT--FGSLL-------------------------------SRLLRL-------LLKEEDKEELEEALEELNE-------- 106

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 168 lgQLAKHprVSALRRFITSWYLSYLTADNTRTQPEagaqerlsptgdnlpnviqylkedhPQRLESILQTLSRRIPRLEK 247
Cdd:COG3593  107 --ELKEA--LKALNELLSEYLKELLDGLDLELELS-------------------------LDELEDLLKSLSLRIEDGKE 157

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 248 VEASIMPNGqlllqikdapFQEPILskfasdgtLKMLAYLTILYDPSPPQVLGIEEPENHLHPRLLPELAEECRA-ATAS 326
Cdd:COG3593  158 LPLDRLGSG----------FQRLIL--------LALLSALAELKRAPANPILLIEEPEAHLHPQAQRRLLKLLKElSEKP 219

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 914399211 327 TQLMVTTHSPFFVDGLKPDEVWVLYRDENGFTQAKRTSAMQGVKEFIQN 375
Cdd:COG3593  220 NQVIITTHSPHLLSEVPLENIRRLRRDSGGTTSTKLIDLDDEDLRKLLR 268
AAA_15 pfam13175
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 8-339 1.44e-16

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433011 [Multi-domain]  Cd Length: 392  Bit Score: 80.72  E-value: 1.44e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211    8 RIENLRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTI---------------FDVFAFLSECFTVGLKKA----WDKRG 68
Cdd:pfam13175   2 KIKSIIIKNFRCLKDTEIDLDEDLTVLIGKNNSGKSSIlealdiflnnkekffEDDFLVLYLKDVIKIDKEdlniFENIS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   69 RFKELRTRGQegYIIIELKYREKFASPLITYHLAINEANNRPYVAEEWLQWRQGARGKPYRFLNFKEGEGIVISGENPQE 148
Cdd:pfam13175  82 FSIDIEIDVE--FLLILFGYLEIKKKYLCLASKGKAKEYEKTLHPKGANKADLLLELKISDLKKYLKQFKIYIYNNYYLD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  149 EDERIYERLDSPEFLAVSTLGQLAKHPRVSA----LRRFITSWYLSYLTADNTRTQPEAG----------AQERLSPTGD 214
Cdd:pfam13175 160 EKKNVFDKKSKYELPSLKEEFLNSEKEEIKVdkedLKKLINELEKSINYHENVLENLQIKkllisadrnaSDEDSEKINS 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  215 NLPNVIQYLKEDHPQRLESILQTLSRRIPRL--------EKVEASIMPNGQLLLQIKDAPFQEPILSKFASDGTLK---- 282
Cdd:pfam13175 240 LLGALKQRIFEEALQEELELTEKLKETQNKLkeidktlaEELKNILFKKIDKLKDFGYPPFLNPEIEIKKDDEDLPlnkn 319

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 914399211  283 -----------MLAYLTILYD---PSPPQVLGIEEPENHLHPRLLPELAEECR--AATASTQLMVTTHSPFFV 339
Cdd:pfam13175 320 gsgvqrlilliFFIAEAERKEdeiEEKNVILAIEEPEAHLHPQAQRVLIKLLKelANDNKTQVIITTHSPHII 392
COG4938 COG4938
Predicted ATPase [General function prediction only];
287-389 1.21e-10

Predicted ATPase [General function prediction only];


Pssm-ID: 443965 [Multi-domain]  Cd Length: 277  Bit Score: 61.52  E-value: 1.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211 287 LTILYDPSPPQVLGIEEPENHLHPRLLPELAEEC-RAATASTQLMVTTHSPFFVDG----------LKPDEVWVLYRDEN 355
Cdd:COG4938  154 LALLSAAKPGSLLIIEEPEAHLHPKAQSALAELLaELANSGVQVIIETHSDYILNGlrnlikegklLDPDDVAVYFFERD 233

                         90       100       110
                 ....*....|....*....|....*....|....
gi 914399211 356 GFTQAKRTSAMQgvkefiQNGALLGqlWMEDYFD 389
Cdd:COG4938  234 GGGSELRRIEID------ENGIISD--WPDGFFD 259
AAA_23 pfam13476
AAA domain;
12-47 7.96e-07

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 49.03  E-value: 7.96e-07
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 914399211   12 LRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTIFD 47
Cdd:pfam13476   1 LTIENFRSFRDQTIDFSKGLTLITGPNGSGKTTILD 36
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
8-52 2.35e-06

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 48.08  E-value: 2.35e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 914399211   8 RIENLRVQNYRALQD---LELKsiAPLTVFLGPNGSGKSTIFDVFAFL 52
Cdd:COG0419    1 KLLRLRLENFRSYRDtetIDFD--DGLNLIVGPNGAGKSTILEAIRYA 46
RecF COG1195
Recombinational DNA repair ATPase RecF [Replication, recombination and repair];
8-45 2.33e-05

Recombinational DNA repair ATPase RecF [Replication, recombination and repair];


Pssm-ID: 440808 [Multi-domain]  Cd Length: 352  Bit Score: 45.92  E-value: 2.33e-05
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 914399211   8 RIENLRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTI 45
Cdd:COG1195    1 RLKRLSLTNFRNYESLELEFSPGINVLVGPNGQGKTNL 38
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 8-52 1.09e-04

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 42.23  E-value: 1.09e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 914399211   8 RIENLRV--QNYRALQDLELKsIAP--LTVFLGPNGSGKSTIFDVFAFL 52
Cdd:cd00267    1 EIENLSFryGGRTALDNVSLT-LKAgeIVALVGPNGSGKSTLLRAIAGL 48
recF PRK00064
recombination protein F; Reviewed
 8-45 1.30e-04

recombination protein F; Reviewed


Pssm-ID: 234608 [Multi-domain]  Cd Length: 361  Bit Score: 43.61  E-value: 1.30e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 914399211   8 RIENLRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTI 45
Cdd:PRK00064   2 YLTRLSLTDFRNYEELDLELSPGVNVLVGENGQGKTNL 39
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 9-47 1.84e-04

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 42.21  E-value: 1.84e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 914399211   9 IENLRVQNYRAL---QDLELKSiaPLTVFLGPNGSGKSTIFD 47
Cdd:cd03240    1 IDKLSIRNIRSFherSEIEFFS--PLTLIVGQNGAGKTTIIE 40
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
8-46 1.86e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.86e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 914399211   8 RIENLRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTIF 46
Cdd:COG4717    2 KIKELEIYGFGKFRDRTIEFSPGLNVIYGPNEAGKSTLL 40
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 8-50 2.64e-04

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 41.27  E-value: 2.64e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 914399211   8 RIENLRV--QNYRALQDLELkSIAP--LTVFLGPNGSGKSTIFDVFA 50
Cdd:cd03214    1 EVENLSVgyGGRTVLDDLSL-SIEAgeIVGILGPNGAGKSTLLKTLA 46
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-46 5.48e-04

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 41.23  E-value: 5.48e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 914399211   1 MSKNSIPRIENLRV--QNYRALQDLELkSIAP--LTVFLGPNGSGKSTIF 46
Cdd:COG1121    1 MMMMPAIELENLTVsyGGRPVLEDVSL-TIPPgeFVAIVGPNGAGKSTLL 49
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 8-76 6.17e-04

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 41.01  E-value: 6.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   8 RIENLRVQ--NYRALQDLELKsIAP--LTVFLGPNGSGKSTIFDVFAFLSECF-------TVGL--KKAWDKRGRFKELR 74
Cdd:cd03260    2 ELRDLNVYygDKHALKDISLD-IPKgeITALIGPSGCGKSTLLRLLNRLNDLIpgapdegEVLLdgKDIYDLDVDVLELR 80


                 ..
gi 914399211  75 TR 76
Cdd:cd03260   81 RR 82
restrict_AAA_1 TIGR04435
restriction system-associated AAA family ATPase; Members of this family are AAA family ATPases ...
 268-362 6.62e-04

restriction system-associated AAA family ATPase; Members of this family are AAA family ATPases by homology. They occur regularly in a conserved gene neighborhood with the restriction (R), modification (M), and specificity (S) proteins of an apparent type I restriction enzyme system, plus one additional uncharacterized protein. It is not clear whether members of this family contribute to restriction per se, or to another process such as transfer of mobile elements.


Pssm-ID: 275228 [Multi-domain]  Cd Length: 555  Bit Score: 41.57  E-value: 6.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  268 QEPILSKFASDGTLKMLAYL-TILYDPSPPQVLGIEEPENHLHP--------RLLPELAEECRAAtASTQLMVTTHSPFF 338
Cdd:TIGR04435 378 EKPVLLKSLSDGEHQLLHSLgLCLLFKDTNSLFLLDEPETHFNPkwrasfisRLRQCLEAGNTKN-VMQEMLITTHSPFL 456

                          90       100
                  ....*....|....*....|....*
gi 914399211  339 VDGLKPDEVWVLYRD-ENGFTQAKR 362
Cdd:TIGR04435 457 ISDCKPENVLVFKKNkENGKVEISL 481
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 8-168 8.09e-04

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 39.65  E-value: 8.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   8 RIENLRVQNYRALQDLELKSiAPLTVFLGPNGSGKSTIFDvfaflSECFTVGLKKAwdKRGRFKELRTRGQEGYIIIELK 87
Cdd:cd03227    1 KIVLGRFPSYFVPNDVTFGE-GSLTIITGPNGSGKSTILD-----AIGLALGGAQS--ATRRRSGVKAGCIVAAVSAELI 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211  88 YR-------EKFASPLItYHLAINEANNRP-YVAEEwlqwrqgargkPYRFLNFKEGEGIVisgenpqeedERIYERLDS 159
Cdd:cd03227   73 FTrlqlsggEKELSALA-LILALASLKPRPlYILDE-----------IDRGLDPRDGQALA----------EAILEHLVK 130


                 ....*....
gi 914399211 160 PEFLAVSTL 168
Cdd:cd03227  131 GAQVIVITH 139
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
8-52 2.02e-03

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 39.61  E-value: 2.02e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 914399211   8 RIENLRV--QNYRALQDLELkSIAP--LTVFLGPNGSGKSTIFDVFAFL 52
Cdd:PRK11231   4 RTENLTVgyGTKRILNDLSL-SLPTgkITALIGPNGCGKSTLLKCFARL 51
RloC COG4694
Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis];
6-54 2.18e-03

Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis];


Pssm-ID: 443729 [Multi-domain]  Cd Length: 692  Bit Score: 40.10  E-value: 2.18e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 914399211   6 IPRIENLRvqNYRALQDL-ELKSIAPLTVFLGPNGSGKSTIFDVFAFLSE 54
Cdd:COG4694    2 ITKIKKLK--NVGAFKDFgWLAFFKKLNLIYGENGSGKSTLSRILRSLEL 49
ABC_RecF cd03242
ATP-binding cassette domain of RecF; RecF is a recombinational DNA repair ATPase that ...
 9-53 2.41e-03

ATP-binding cassette domain of RecF; RecF is a recombinational DNA repair ATPase that maintains replication in the presence of DNA damage. When replication is prematurely disrupted by DNA damage, several recF pathway gene products play critical roles processing the arrested replication fork, allowing it to resume and complete its task. This CD represents the nucleotide binding domain of RecF. RecF belongs to a large superfamily of ABC transporters involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases with a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213209 [Multi-domain]  Cd Length: 270  Bit Score: 39.20  E-value: 2.41e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 914399211   9 IENLRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTIFDVFAFLS 53
Cdd:cd03242    1 LKSLELRNFRNYAELELEFEPGVTVLVGENAQGKTNLLEAISLLA 45
ABC_SMC_head cd03239
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ...
 9-86 2.62e-03

The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.


Pssm-ID: 213206 [Multi-domain]  Cd Length: 178  Bit Score: 38.44  E-value: 2.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   9 IENLRVQNYRALQDLELKSIA-PLTVFLGPNGSGKSTIFDvfaflSECFTVGLKKAWDKRGRFKEL-----RTRGQEGYI 82
Cdd:cd03239    1 IKQITLKNFKSYRDETVVGGSnSFNAIVGPNGSGKSNIVD-----AICFVLGGKAAKLRRGSLLFLagggvKAGINSASV 75


                 ....
gi 914399211  83 IIEL 86
Cdd:cd03239   76 EITF 79
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 8-44 3.76e-03

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 38.49  E-value: 3.76e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 914399211   8 RIENLRVQ--NYRALQDLELkSIAP--LTVFLGPNGSGKST 44
Cdd:COG1120    3 EAENLSVGygGRPVLDDVSL-SLPPgeVTALLGPNGSGKST 42
AAA_29 pfam13555
P-loop containing region of AAA domain;
32-52 4.03e-03

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 35.27  E-value: 4.03e-03
                          10        20
                  ....*....|....*....|.
gi 914399211   32 TVFLGPNGSGKSTIFDVFAFL 52
Cdd:pfam13555  25 TLLTGPSGSGKSTLLDAIQTL 45
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-45 4.85e-03

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 38.54  E-value: 4.85e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 914399211   1 MSKNSIpRIENLRVQ--NYRALQDLELkSIAP--LTVFLGPNGSGKSTI 45
Cdd:COG3842    1 MAMPAL-ELENVSKRygDVTALDDVSL-SIEPgeFVALLGPSGCGKTTL 47
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 8-46 5.16e-03

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 37.90  E-value: 5.16e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 914399211   8 RIENLRV--QNYRALQDLELkSIAP--LTVFLGPNGSGKSTIF 46
Cdd:cd03235    1 EVEDLTVsyGGHPVLEDVSF-EVKPgeFLAIVGPNGAGKSTLL 42
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 5-45 5.21e-03

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 38.59  E-value: 5.21e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 914399211   5 SIpRIENL--RVQNYRALQDLELkSIAP--LTVFLGPNGSGKSTI 45
Cdd:COG1118    2 SI-EVRNIskRFGSFTLLDDVSL-EIASgeLVALLGPSGSGKTTL 44
COG3910 COG3910
Predicted ATPase [General function prediction only];
18-45 5.55e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443116 [Multi-domain]  Cd Length: 239  Bit Score: 38.21  E-value: 5.55e-03
                         10        20
                 ....*....|....*....|....*...
gi 914399211  18 RALQDLELKSiaPLTVFLGPNGSGKSTI 45
Cdd:COG3910   28 RNLEGLEFHP--PVTFFVGENGSGKSTL 53
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
8-44 7.54e-03

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 37.79  E-value: 7.54e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 914399211   8 RIENLRVQ--NYRALQDLELkSIAP--LTVFLGPNGSGKST 44
Cdd:COG4559    3 EAENLSVRlgGRTLLDDVSL-TLRPgeLTAIIGPNGAGKST 42
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
8-44 7.76e-03

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 37.74  E-value: 7.76e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 914399211   8 RIENLRVQ--NYRALQDLELkSIAP--LTVFLGPNGSGKST 44
Cdd:COG1131    2 EVRGLTKRygDKTALDGVSL-TVEPgeIFGLLGPNGAGKTT 41
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 8-44 8.44e-03

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 38.13  E-value: 8.44e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 914399211   8 RIENL--RVQNYRALQDLELkSIAP--LTVFLGPNGSGKST 44
Cdd:COG3839    5 ELENVskSYGGVEALKDIDL-DIEDgeFLVLLGPSGCGKST 44
ABC_SMC5_euk cd03277
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of ...
 5-91 8.86e-03

ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213244 [Multi-domain]  Cd Length: 213  Bit Score: 37.19  E-value: 8.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 914399211   5 SIPRIenlRVQNYRALQDLELKSIAPLTVFLGPNGSGKSTIfdVFAFlseCFTVGLKKAWdkRGRFKEL----RTRGQEG 80
Cdd:cd03277    2 SIVRI---KLENFVTYDETEFRPGPSLNMIIGPNGSGKSSI--VCAI---CLGLGGKPKL--LGRAKKVgefvKRGCDEG 71

                         90
                 ....*....|.
gi 914399211  81 YIIIELKYREK 91
Cdd:cd03277   72 TIEIELYGNPG 82
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 8-48 9.21e-03

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 37.42  E-value: 9.21e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 914399211   8 RIENLRVQ--NYRALQDLELkSIAP--LTVFLGPNGSGKSTIFDV 48
Cdd:cd03219    2 EVRGLTKRfgGLVALDDVSF-SVRPgeIHGLIGPNGAGKTTLFNL 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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