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Conserved domains on  [gi|902554576|gb|AKR78533|]
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glucosamine-6-phosphate deaminase [Edwardsiella sp. LADL05-105]

Protein Classification

glucosamine-6-phosphate deaminase( domain architecture ID 10011441)

glucosamine-6-phosphate deaminase catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and an ammonium ion

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
nagB PRK00443
glucosamine-6-phosphate deaminase; Provisional
 1-261 1.62e-177

glucosamine-6-phosphate deaminase; Provisional


:

Pssm-ID: 179028 [Multi-domain]  Cd Length: 261  Bit Score: 488.57  E-value: 1.62e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   1 MRLIPLHNATDVGLWSARHIVKRINAFKPTAERPFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAES 80
Cdd:PRK00443   1 MRLIILKTAEEVGKWAARHIANRINAFLPTKERPFVLGLATGSSPLETYKALIELHKAGKVDFSRVTTFNLDEYVGLPAD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  81 HPESYHSFMYNNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIK 160
Cdd:PRK00443  81 HPESYRYFMRENFFDHVDIPPENINLLNGNAPDPEAECRRYEEKIKSAGGIDLQILGIGENGHIAFNEPGSSFASRTRIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576 161 TLTEDTRIANSRFFNGDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCD 240
Cdd:PRK00443 161 TLTEDTRIANSRFFDGDIEQVPKYALTVGVGTILDAKEIMLLAPGHNKAEAVKAAVEGPVNHMWPASILQLHPKATLVLD 240

                        250       260
                 ....*....|....*....|.
gi 902554576 241 QPATMELKVKTVNYFRELEAE 261
Cdd:PRK00443 241 EAAASELKVKTVKYFTELEAE 261
 
Name Accession Description Interval E-value
nagB PRK00443
glucosamine-6-phosphate deaminase; Provisional
 1-261 1.62e-177

glucosamine-6-phosphate deaminase; Provisional


Pssm-ID: 179028 [Multi-domain]  Cd Length: 261  Bit Score: 488.57  E-value: 1.62e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   1 MRLIPLHNATDVGLWSARHIVKRINAFKPTAERPFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAES 80
Cdd:PRK00443   1 MRLIILKTAEEVGKWAARHIANRINAFLPTKERPFVLGLATGSSPLETYKALIELHKAGKVDFSRVTTFNLDEYVGLPAD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  81 HPESYHSFMYNNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIK 160
Cdd:PRK00443  81 HPESYRYFMRENFFDHVDIPPENINLLNGNAPDPEAECRRYEEKIKSAGGIDLQILGIGENGHIAFNEPGSSFASRTRIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576 161 TLTEDTRIANSRFFNGDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCD 240
Cdd:PRK00443 161 TLTEDTRIANSRFFDGDIEQVPKYALTVGVGTILDAKEIMLLAPGHNKAEAVKAAVEGPVNHMWPASILQLHPKATLVLD 240

                        250       260
                 ....*....|....*....|.
gi 902554576 241 QPATMELKVKTVNYFRELEAE 261
Cdd:PRK00443 241 EAAASELKVKTVKYFTELEAE 261
nagB TIGR00502
glucosamine-6-phosphate isomerase; The set of proteins recognized by this model includes a ...
 1-259 1.22e-173

glucosamine-6-phosphate isomerase; The set of proteins recognized by this model includes a closely related pair from Bacillus subtilis, one of which is uncharacterized but included as a member of the orthologous set. [Central intermediary metabolism, Amino sugars]


Pssm-ID: 129593  Cd Length: 259  Bit Score: 478.92  E-value: 1.22e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576    1 MRLIPLHNATDVGLWSARHIVKRINAFKPTAERPFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAES 80
Cdd:TIGR00502   1 MRLIILQTYEELSKWAARHIANRINEFKPTAARPFVLGLPTGGTPIGTYKQLIELHQAGKISFQNVTTFNMDEYAGLSEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   81 HPESYHSFMYNNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIK 160
Cdd:TIGR00502  81 HPESYHSFMHNNFFQHIDIKPENINILNGNAPDLEAECRRYEEKIRSYGGIDLFMGGIGPDGHIAFNEPGSSLTSRTRIK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  161 TLTEDTRIANSRFFNGDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCD 240
Cdd:TIGR00502 161 TLTEDTIQANSRFFEGDVNQVPKYALTVGIGTILDSKEVLILVSGHQKALALQKAVEGGVNHMWTISALQLHKHAIVVCD 240

                         250
                  ....*....|....*....
gi 902554576  241 QPATMELKVKTVNYFRELE 259
Cdd:TIGR00502 241 ENATQELKVKTVEYFNELE 259
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 11-247 3.13e-130

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 367.97  E-value: 3.13e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  11 DVGLWSARHIVKRINAFKPtaerpFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAESHPESYHSFMY 90
Cdd:cd01399    2 EMSEAAAELIAELIREKPP-----AVLGLATGSTPLGVYEELIELHKEGGLSFSNVTTFNLDEYVGLPPDHPQSYHYFMR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  91 NNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIKTLTEDTRIAN 170
Cdd:cd01399   77 ENLFDHIDIKPENIHIPDGNAADLEAECRRYEALIAEAGGIDLQLLGIGENGHIGFNEPGSSLDSRTRVVTLDESTRQAN 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 902554576 171 SRFFNGDiSLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCDQPATMEL 247
Cdd:cd01399  157 ARFFDGD-EDVPTQAITMGIGTIMKAKEILLLATGEGKAEAVKKALEGPVTEECPASILQLHPNVTVILDEAAASEL 232
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 1-248 7.47e-115

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 329.81  E-value: 7.47e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   1 MRLIPLHNATDVGLWSARHIVKRINAFkpTAERP-FVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAE 79
Cdd:COG0363    2 MRVIIFPDAEELAAAAAERAAERIAEA--IAEKGrAVLGLAGGSTPLGLYEELARLHKEGGLDWSRVHVFNLDEYVGLPP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  80 SHPESYHSFMYNNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRT-R 158
Cdd:COG0363   80 DHPQSNRRFMREALLDHVDIPPENIHIPDGEAEDPEAAAARYEALIAEAGGIDLQLLGIGEDGHIAFNFPGSPFLSETdR 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576 159 IKTLTEDTRIANSRFFnGDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVV 238
Cdd:COG0363  160 VVTLDESTRQANARFF-GSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPASILQGHPNVTWF 238

                        250
                 ....*....|
gi 902554576 239 CDQPATMELK 248
Cdd:COG0363  239 LDEAAASLLT 248
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
17-223 1.95e-19

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 83.83  E-value: 1.95e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   17 ARHIVKRINAFkpTAER-PFVLGLPTGSTPLQTYKRLIELYQAgeVSFRHVVTFNMDE-YVglAESHPESYHSFMYNNFF 94
Cdd:pfam01182  11 AERLAEALEAA--LAERgRFTLALSGGSTPKPLYELLAAAPAR--LDWSRVHVFWGDErCV--PPDDPDSNYGMAREALL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   95 NHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKIN------LFMGGVGNDGHIA--F-NEPAssLASRTRIKTLTED 165
Cdd:pfam01182  85 SHVPIPASNVHPIPASAADPEEAAAAYEAELRELLPDLelpvfdLVLLGMGPDGHTAslFpGSPA--LEETDRLVVAVTD 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 902554576  166 TRIAnsrffngdislvPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHM 223
Cdd:pfam01182 163 SPKP------------PPERITLTLPVLNAARRVWFLVTGAGKADALRRALAGDPDPL 208
 
Name Accession Description Interval E-value
nagB PRK00443
glucosamine-6-phosphate deaminase; Provisional
 1-261 1.62e-177

glucosamine-6-phosphate deaminase; Provisional


Pssm-ID: 179028 [Multi-domain]  Cd Length: 261  Bit Score: 488.57  E-value: 1.62e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   1 MRLIPLHNATDVGLWSARHIVKRINAFKPTAERPFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAES 80
Cdd:PRK00443   1 MRLIILKTAEEVGKWAARHIANRINAFLPTKERPFVLGLATGSSPLETYKALIELHKAGKVDFSRVTTFNLDEYVGLPAD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  81 HPESYHSFMYNNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIK 160
Cdd:PRK00443  81 HPESYRYFMRENFFDHVDIPPENINLLNGNAPDPEAECRRYEEKIKSAGGIDLQILGIGENGHIAFNEPGSSFASRTRIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576 161 TLTEDTRIANSRFFNGDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCD 240
Cdd:PRK00443 161 TLTEDTRIANSRFFDGDIEQVPKYALTVGVGTILDAKEIMLLAPGHNKAEAVKAAVEGPVNHMWPASILQLHPKATLVLD 240

                        250       260
                 ....*....|....*....|.
gi 902554576 241 QPATMELKVKTVNYFRELEAE 261
Cdd:PRK00443 241 EAAASELKVKTVKYFTELEAE 261
nagB TIGR00502
glucosamine-6-phosphate isomerase; The set of proteins recognized by this model includes a ...
 1-259 1.22e-173

glucosamine-6-phosphate isomerase; The set of proteins recognized by this model includes a closely related pair from Bacillus subtilis, one of which is uncharacterized but included as a member of the orthologous set. [Central intermediary metabolism, Amino sugars]


Pssm-ID: 129593  Cd Length: 259  Bit Score: 478.92  E-value: 1.22e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576    1 MRLIPLHNATDVGLWSARHIVKRINAFKPTAERPFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAES 80
Cdd:TIGR00502   1 MRLIILQTYEELSKWAARHIANRINEFKPTAARPFVLGLPTGGTPIGTYKQLIELHQAGKISFQNVTTFNMDEYAGLSEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   81 HPESYHSFMYNNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIK 160
Cdd:TIGR00502  81 HPESYHSFMHNNFFQHIDIKPENINILNGNAPDLEAECRRYEEKIRSYGGIDLFMGGIGPDGHIAFNEPGSSLTSRTRIK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  161 TLTEDTRIANSRFFNGDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCD 240
Cdd:TIGR00502 161 TLTEDTIQANSRFFEGDVNQVPKYALTVGIGTILDSKEVLILVSGHQKALALQKAVEGGVNHMWTISALQLHKHAIVVCD 240

                         250
                  ....*....|....*....
gi 902554576  241 QPATMELKVKTVNYFRELE 259
Cdd:TIGR00502 241 ENATQELKVKTVEYFNELE 259
PTZ00285 PTZ00285
glucosamine-6-phosphate isomerase; Provisional
 1-252 5.72e-148

glucosamine-6-phosphate isomerase; Provisional


Pssm-ID: 140308  Cd Length: 253  Bit Score: 413.77  E-value: 5.72e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   1 MRLIPLHNATDVGLWSARHIVKRINAFKPTAERPFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAES 80
Cdd:PTZ00285   1 MRIVISEDADAVADYTSNYIIKRINDFKPTSDRPFVLGLPTGSTPLPTYQELIRAYREGRVSFSNVVTFNMDEYVGLPRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  81 HPESYHSFMYNNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIK 160
Cdd:PTZ00285  81 HPQSYHYFMKENFFDHVDIKEENRHILNGTAPDLEEECRRYEEKIRAVGGIDLFLAGIGTDGHIAFNEPGSSLDSRTRVK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576 161 TLTEDTRIANSRFFNGDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCD 240
Cdd:PTZ00285 161 SLNQETIDANARFFGNDISKVPTMALTVGIRTIMEAREVLLLATGASKAIAVARCVEGGVTHMCPASALQMHPAAVLCLD 240

                        250
                 ....*....|..
gi 902554576 241 QPATMELKVKTV 252
Cdd:PTZ00285 241 EDATLELKVKTT 252
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 11-247 3.13e-130

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 367.97  E-value: 3.13e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  11 DVGLWSARHIVKRINAFKPtaerpFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAESHPESYHSFMY 90
Cdd:cd01399    2 EMSEAAAELIAELIREKPP-----AVLGLATGSTPLGVYEELIELHKEGGLSFSNVTTFNLDEYVGLPPDHPQSYHYFMR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  91 NNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIKTLTEDTRIAN 170
Cdd:cd01399   77 ENLFDHIDIKPENIHIPDGNAADLEAECRRYEALIAEAGGIDLQLLGIGENGHIGFNEPGSSLDSRTRVVTLDESTRQAN 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 902554576 171 SRFFNGDiSLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCDQPATMEL 247
Cdd:cd01399  157 ARFFDGD-EDVPTQAITMGIGTIMKAKEILLLATGEGKAEAVKKALEGPVTEECPASILQLHPNVTVILDEAAASEL 232
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 1-248 7.47e-115

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 329.81  E-value: 7.47e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   1 MRLIPLHNATDVGLWSARHIVKRINAFkpTAERP-FVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAE 79
Cdd:COG0363    2 MRVIIFPDAEELAAAAAERAAERIAEA--IAEKGrAVLGLAGGSTPLGLYEELARLHKEGGLDWSRVHVFNLDEYVGLPP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  80 SHPESYHSFMYNNFFNHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRT-R 158
Cdd:COG0363   80 DHPQSNRRFMREALLDHVDIPPENIHIPDGEAEDPEAAAARYEALIAEAGGIDLQLLGIGEDGHIAFNFPGSPFLSETdR 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576 159 IKTLTEDTRIANSRFFnGDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVV 238
Cdd:COG0363  160 VVTLDESTRQANARFF-GSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPASILQGHPNVTWF 238

                        250
                 ....*....|
gi 902554576 239 CDQPATMELK 248
Cdd:COG0363  239 LDEAAASLLT 248
PRK02122 PRK02122
glucosamine-6-phosphate deaminase-like protein; Validated
 17-247 1.37e-74

glucosamine-6-phosphate deaminase-like protein; Validated


Pssm-ID: 235005 [Multi-domain]  Cd Length: 652  Bit Score: 239.16  E-value: 1.37e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  17 ARHIVKRINAF---KPTAERPFVLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAESHPESYHSFMYNNF 93
Cdd:PRK02122  40 SRAVAQEIATLireRQAEGKPCVLGLATGSSPIGVYAELIRMHREEGLSFKNVITFNLDEYYPMQPDSLQSYHRFMKENL 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  94 FNHIDIQKENINLLNGNAP--DVDAECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIKTLTEDTRIANS 171
Cdd:PRK02122 120 FDHVDIPPENIHIPDGTIPkeEIDEYCRDYEEKIEAAGGIDFQLLGIGRTGHIGFNEPGSGRNSRTRLVTLDHITRRDAA 199

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 902554576 172 RFFNGdISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCDQPATMEL 247
Cdd:PRK02122 200 SDFFG-EENVPRKAITMGVGTILKARRIVLLAWGEHKAPIIKRAVEGEISDEVPASYLQEHPNATFVLDLAAASEL 274
SugarP_isomerase cd00458
SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate ...
 15-239 1.75e-56

SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium, the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate. 6PGL converts 6-phosphoglucono-1,5-lactone to 6-phosphogluconate, the second step of the oxidative phase of the pentose phosphate pathway.


Pssm-ID: 238258  Cd Length: 169  Bit Score: 178.70  E-value: 1.75e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  15 WSARHIVKRINAFkPTAERPFVLGLPTGSTPLQTYKRLIELYQAGEvsFRHVVTFNMDEYVGLAEsHPESYHSFMYNNFF 94
Cdd:cd00458    3 EALKFIEDK*EKL-LEEKDDMVIGLGTGSTPAYFYKLLGEKLKRGE--ISDIVGFPTDERYVPLD-SDQSNFRQAKLLAF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  95 NHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKINLFMGGVGNdghiafnepasslasrtriktltedtriansrff 174
Cdd:cd00458   79 EHDIIPASNVHYVDTSLPIEKACEKYEREILDQVDAIDLAVDGAGY---------------------------------- 124

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 902554576 175 ngdislvpkyaltvgvgtllDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVC 239
Cdd:cd00458  125 --------------------RAGTVIVLVDGRKKVDYLCQNTEPGVIENGIFADIRGKEKDIVIV 169
PRK09762 PRK09762
galactosamine-6-phosphate isomerase; Provisional
 36-239 1.63e-34

galactosamine-6-phosphate isomerase; Provisional


Pssm-ID: 182064  Cd Length: 232  Bit Score: 124.17  E-value: 1.63e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  36 VLGLPTGSTPLQTYKRLIELYQAGEVSFRHVVTFNMDEYVGLAESHPESYHSFMYNNFFNHIDIQKENINLLNGNAPDvD 115
Cdd:PRK09762  31 VICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETFLQQHIVQPLGLREDQLISFRSEEIN-E 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576 116 AECRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPASSLASRTRIKTLTEDTRiaNSRFFNGDiSLVPKYALTVGVGTLLD 195
Cdd:PRK09762 110 TECERVTNLIARKGGLDLCVLGLGKNGHLGLNEPGESLQPACHISQLDARTQ--QHEMLKTA-GRPVTRGITLGLKDILN 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 902554576 196 AEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKsvVVC 239
Cdd:PRK09762 187 AREVLLLVTGEGKQDATERFLTAKVSTAIPASFLWLHSN--FIC 228
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
22-247 4.33e-20

glucosamine-6-phosphate deaminase;


Pssm-ID: 183470  Cd Length: 239  Bit Score: 86.34  E-value: 4.33e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  22 KRINafkptaerpfvLGLPTGSTPLQTYKRLIELYQaGEVSFRHVVTFNMDEYVGLAESHPESYHSFMYNNFFNHIDIQK 101
Cdd:PRK12358  28 KRVN-----------LAITAGSTPKGMYEYLITLVK-GKAWYDNVHYYNFDEIPFRGKEGEGVTITNLRNLFFTPAGIKE 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576 102 ENINLLN-GNApdvdaecRRYEEKIRAYGKINLFMGGVGNDGHIAFNEPA-SSLASRTRIKTLTEDT-RIANSRFFNGDI 178
Cdd:PRK12358  96 ENIHKLTiDNY-------REHDQKLARDGGLDLVVLGLGADGHFCGNLPGtTHFHDETVEVPIQGEMvDIVAHGELGGDF 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 902554576 179 SLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVCDQPATMEL 247
Cdd:PRK12358 169 SLVPDSYVTMGPKSIMAAKNLLLIVNGKGKAQILKKVLQGPVTEDVPASILQLHPNLTVILDEAAAAEL 237
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
17-223 1.95e-19

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 83.83  E-value: 1.95e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   17 ARHIVKRINAFkpTAER-PFVLGLPTGSTPLQTYKRLIELYQAgeVSFRHVVTFNMDE-YVglAESHPESYHSFMYNNFF 94
Cdd:pfam01182  11 AERLAEALEAA--LAERgRFTLALSGGSTPKPLYELLAAAPAR--LDWSRVHVFWGDErCV--PPDDPDSNYGMAREALL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   95 NHIDIQKENINLLNGNAPDVDAECRRYEEKIRAYGKIN------LFMGGVGNDGHIA--F-NEPAssLASRTRIKTLTED 165
Cdd:pfam01182  85 SHVPIPASNVHPIPASAADPEEAAAAYEAELRELLPDLelpvfdLVLLGMGPDGHTAslFpGSPA--LEETDRLVVAVTD 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 902554576  166 TRIAnsrffngdislvPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHM 223
Cdd:pfam01182 163 SPKP------------PPERITLTLPVLNAARRVWFLVTGAGKADALRRALAGDPDPL 208
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 17-239 1.88e-17

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 78.37  E-value: 1.88e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  17 ARHIVKRINAFkpTAER-PFVLGLPTGSTPLQTYKRLIELYQageVSFRHVVTFNMDE-YVglAESHPESYHSFMYNNFF 94
Cdd:cd01400    8 ADRIAEALAAA--IAKRgRFSLALSGGSTPKPLYELLAAAPA---LDWSKVHVFLGDErCV--PPDDPDSNYRLAREALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  95 NHIDIQKENINLLNGNApDVDAECRRYEEKIRA----YGKINLFMGGVGNDGHIA--FnePASSLAsrtriktLTEDTR- 167
Cdd:cd01400   81 SHVAIPAANIHPIPTEL-GPEDAAAAYEKELRAlfggVPPFDLVLLGMGPDGHTAslF--PGHPAL-------LEETDRl 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 902554576 168 -IANSrffngDISLVPKYALTVGVGTLLDAEEVMILVTGHAKSLALQAAVEGSVNHMWTISALQLHPKSVVVC 239
Cdd:cd01400  151 vVAVT-----DSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKRALAGPDPEELPAARVLPRPGEVLWF 218
pgl TIGR01198
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ...
 35-243 1.32e-09

6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273494 [Multi-domain]  Cd Length: 233  Bit Score: 57.00  E-value: 1.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576   35 FVLGLPTGSTPLQTYKRLIELyqagEVSFRHVVTFNMDE-YVglAESHPESYHSFMYNNFFNHIDIQKENINLLNGNAPD 113
Cdd:TIGR01198  30 FSLALSGGRSPIALLEALAAQ----PLDWSRIHLFLGDErYV--PLDHADSNTGLAREALLDRVAIPASNIHPMPTELSD 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902554576  114 VDAECRRYEEKIRAY------GKINLFMGGVGNDGHIAfnepasSLASRTRIKTLTEDTRIansrFFNGDISlVPKYALT 187
Cdd:TIGR01198 104 IEEAAELYEQELAAAfqpivfPVFDLLLLGMGPDGHTA------SLFPHTPALQETERLVT----VLTKSPK-PPHERIT 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 902554576  188 VGVGTLLDAEEVMILVTGHAKSLALQAAVE-GSVNHMWTISALQLHPKSVVVCDQPA 243
Cdd:TIGR01198 173 LTLPAINAARKVFLLIAGEEKRNALAEALAvEAEPYPLPAAGVLHSGKTLWLLDYAA 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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