|
Name |
Accession |
Description |
Interval |
E-value |
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-252 |
1.30e-165 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 458.01 E-value: 1.30e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:COG4604 1 MIEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKRLAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:COG4604 81 RQENHINSRLTVRELVAFGRFPYSKGRLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEMDVHIE 240
Cdd:COG4604 161 EPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEIITPEVLSDIYDTDIEVE 240
|
250
....*....|..
gi 807234162 241 EIRGQRICLYYD 252
Cdd:COG4604 241 EIDGKRICVYFR 252
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-249 |
3.50e-106 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 307.74 E-value: 3.50e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFGRFPYSK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:COG1120 81 PQEPPAPFGLTVRELVALGRYPHLGlfGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEMDVH 238
Cdd:COG1120 161 LDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEEVYGVEAR 240
|
250
....*....|...
gi 807234162 239 IEE--IRGQRICL 249
Cdd:COG1120 241 VIEdpVTGRPLVL 253
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-249 |
5.24e-79 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 238.76 E-value: 5.24e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:PRK11231 2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFGRFPYSK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:PRK11231 82 PQHHLTPEGITVRELVAYGRSPWLSlwGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEMDVH 238
Cdd:PRK11231 162 LDEPTTYLDINHQVELMRLMREL-NTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRTVFDVEAE 240
|
250
....*....|...
gi 807234162 239 I--EEIRGQRICL 249
Cdd:PRK11231 241 IhpEPVSGTPMCV 253
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-217 |
2.35e-74 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 224.24 E-value: 2.35e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQ 82
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 83 tnhtemnitveqlvnfgrfpyskgrmkkedyeqveyALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEP 162
Cdd:cd03214 81 ------------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEP 124
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 163 LNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKA 217
Cdd:cd03214 125 TSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQ 179
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-239 |
5.97e-68 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 210.33 E-value: 5.97e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdyknDDLAKKLSIL 80
Cdd:COG1121 6 AIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPP-----RRARRRIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQtnHTEMN----ITVEQLVNFGRFPYSK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDT 154
Cdd:COG1121 81 PQ--RAEVDwdfpITVRDVVLMGRYGRRGlfRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 155 DYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALkNGEIVKADTKDNVIQAEILKQLYE 234
Cdd:COG1121 159 DLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLL-NRGLVAHGPPEEVLTPENLSRAYG 236
|
....*
gi 807234162 235 MDVHI 239
Cdd:COG1121 237 GPVAL 241
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-239 |
5.93e-65 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 203.04 E-value: 5.93e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:COG4559 1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRAVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQtnHTEMN--ITVEQLVNFGRFPYskGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ---DTD 155
Cdd:COG4559 81 PQ--HSSLAfpFTVEEVVALGRAPH--GSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAQlwePVD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 156 ----YILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQ 231
Cdd:COG4559 157 ggprWLFLDEPTSALDLAHQHAVLRLARQLARR-GGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEVLTDELLER 235
|
....*...
gi 807234162 232 LYEMDVHI 239
Cdd:COG4559 236 VYGADLRV 243
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-239 |
1.18e-64 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 202.31 E-value: 1.18e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:PRK13548 2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAVL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFGRFPYskGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ------DT 154
Cdd:PRK13548 82 PQHSSLSFPFTVEEVVAMGRAPH--GLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAQlwepdgPP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 155 DYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYE 234
Cdd:PRK13548 160 RWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVLTPETLRRVYG 239
|
....*
gi 807234162 235 MDVHI 239
Cdd:PRK13548 240 ADVLV 244
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
3-215 |
9.10e-59 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 185.81 E-value: 9.10e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKnddlaKKLSILKQ 82
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKER-----KRIGYVPQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 83 TNH--TEMNITVEQLVNFGRFPYSK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:cd03235 76 RRSidRDFPISVRDVVLMGLYGHKGlfRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALkNGEIV 215
Cdd:cd03235 156 LDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLL-NRTVV 210
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
5-239 |
2.87e-57 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 183.65 E-value: 2.87e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 5 KNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTN 84
Cdd:PRK10253 11 EQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 85 HTEMNITVEQLVNFGRFPYSK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEP 162
Cdd:PRK10253 91 TTPGDITVQELVARGRYPHQPlfTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEP 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 163 LNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEMDVHI 239
Cdd:PRK10253 171 TTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIYGLRCMI 247
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
4-233 |
1.86e-55 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 179.21 E-value: 1.86e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 4 IKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQT 83
Cdd:PRK10575 14 LRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 84 NHTEMNITVEQLVNFGRFPY--SKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:PRK10575 94 LPAAEGMTVRELVAIGRYPWhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDE 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLY 233
Cdd:PRK10575 174 PTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGETLEQIY 245
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
1-233 |
2.72e-55 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 177.88 E-value: 2.72e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDL----AK 75
Cdd:TIGR02315 1 MLEVENLSKVYPNgKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLrklrRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 KLSILKQTNHTEmNITVEQLVNFGRFPYSK------GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMT 149
Cdd:TIGR02315 81 IGMIFQHYNLIE-RLTVLENVLHGRLGYKPtwrsllGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVkADTKDNVIQAEIL 229
Cdd:TIGR02315 160 LAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIV-FDGAPSELDDEVL 238
|
....
gi 807234162 230 KQLY 233
Cdd:TIGR02315 239 RHIY 242
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-233 |
2.15e-53 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 172.75 E-value: 2.15e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLS-- 78
Cdd:cd03256 1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLRRqi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 --ILKQTNHTEmNITVEQLVNFGRFPYSK------GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTI 150
Cdd:cd03256 81 gmIFQQFNLIE-RLSVLENVLSGRLGRRStwrslfGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVkADTKDNVIQAEILK 230
Cdd:cd03256 160 MQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIV-FDGPPAELTDEVLD 238
|
...
gi 807234162 231 QLY 233
Cdd:cd03256 239 EIY 241
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
1-233 |
6.51e-53 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 171.78 E-value: 6.51e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK---K 76
Cdd:COG3638 2 MLELRNLSKRYPGgTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRRlrrR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEMNITVEQLVNFGRFPYSK------GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTI 150
Cdd:COG3638 82 IGMIFQQFNLVPRLSVLTNVLAGRLGRTStwrsllGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAIARAL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVkADTKDNVIQAEILK 230
Cdd:COG3638 162 VQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVV-FDGPPAELTDAVLR 240
|
...
gi 807234162 231 QLY 233
Cdd:COG3638 241 EIY 243
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-239 |
7.17e-53 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 171.58 E-value: 7.17e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVdYKNDDLAKKLSIL 80
Cdd:COG4555 1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVR-KEPREARRQIGVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVN-FGRFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:COG4555 80 PDERGLYDRLTVRENIRyFAEL---YGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEMDVHI 239
Cdd:COG4555 157 DEPTNGLDVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEENLEDAFVAL 235
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
12-213 |
1.73e-52 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 169.57 E-value: 1.73e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQ-TNHTEMNI 90
Cdd:cd03225 12 GARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLVFQnPDDQFFGP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 TVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKH 170
Cdd:cd03225 92 TVEEEVAFG--LENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAG 169
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 807234162 171 SVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGE 213
Cdd:cd03225 170 RRELLELLKKL-KAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-231 |
2.13e-51 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 167.51 E-value: 2.13e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:COG1122 1 IELENLSFSYPGgTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQtnHTEMNI---TVEQ-----LVNFGrfpYSKGRMKkedyEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:COG1122 81 FQ--NPDDQLfapTVEEdvafgPENLG---LPREEIR----ERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAM 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI-QAEILKQ 231
Cdd:COG1122 152 EPEVLVLDEPTAGLDPRGRRELLELLKRL-NKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFsDYELLEE 230
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-214 |
2.08e-48 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 159.19 E-value: 2.08e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKA----IQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLA--- 74
Cdd:cd03255 1 IELKNLSKTygggGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 -KKLSILKQTNHTEMNITVEQLVNFGRFPysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:cd03255 81 rRHIGFVFQSFNLLPDLTALENVELPLLL--AGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALAND 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEI 214
Cdd:cd03255 159 PKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAE-YADRIIELRDGKI 218
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-233 |
1.10e-47 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 157.92 E-value: 1.10e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDyKNDDLAKKLSILK 81
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVAR-DPAEVRRRIGYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQ-LVNFGRFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:COG1131 80 QEPALYPDLTVREnLRFFARL---YGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILD 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIqAEILKQLY 233
Cdd:COG1131 157 EPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELK-ARLLEDVF 227
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-226 |
2.24e-43 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 153.52 E-value: 2.24e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAI--QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE---KGTIKIEGKAVVDYKNDDLAK 75
Cdd:COG1123 4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALRGR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 KLSILKQTNHTEMN-ITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDT 154
Cdd:COG1123 84 RIGMVFQDPMTQLNpVTVGDQIAEA--LENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 155 DYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQA 226
Cdd:COG1123 162 DLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAA 233
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-230 |
2.72e-43 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 151.15 E-value: 2.72e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:PRK09536 3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFGRFPYSK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:PRK09536 83 PQDTSLSFEFDVRQVVEMGRTPHRSrfDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLL 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILK 230
Cdd:PRK09536 163 LDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLR 233
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-216 |
1.97e-42 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 144.42 E-value: 1.97e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK- 75
Cdd:COG1136 4 LLELRNLTKSYGTGegevTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARl 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 ----------------KLSILKqtnhtemNITVEQLVNfgrfpyskGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGG 139
Cdd:COG1136 84 rrrhigfvfqffnllpELTALE-------NVALPLLLA--------GVSRKERRERARELLERVGLGDRLDHRPSQLSGG 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 140 QRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEIVK 216
Cdd:COG1136 149 QQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAA-RADRVIRLRDGRIVS 224
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-226 |
8.82e-42 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 149.28 E-value: 8.82e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDK-----AIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDD--- 72
Cdd:COG1123 260 LLEVRNLSKrypvrGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSlre 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 LAKKLSILKQTNHTEMN--ITVEQ-----LVNFGRFPyskgrmKKEDYEQVEYALDLLQLQ-SIRHRNIKTLSGGQRQRA 144
Cdd:COG1123 340 LRRRVQMVFQDPYSSLNprMTVGDiiaepLRLHGLLS------RAERRERVAELLERVGLPpDLADRYPHELSGGQRQRV 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:COG1123 414 AIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVF 493
|
..
gi 807234162 225 QA 226
Cdd:COG1123 494 AN 495
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
2-224 |
1.43e-41 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 142.44 E-value: 1.43e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:cd03295 1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRKIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQlvNFGRFPYSKGRMKKEDYEQVEYALDLLQL--QSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:cd03295 81 IQQIGLFPHMTVEE--NIALVPKLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:cd03295 159 MDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEIL 224
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-215 |
1.76e-41 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 141.50 E-value: 1.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDlaKKLSILK 81
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPER--RNIGMVF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03259 79 QDYALFPHLTVAENIAFG--LKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03259 157 PLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIV 210
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
17-246 |
3.82e-41 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 141.52 E-value: 3.82e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEkGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTEMNITVEQLV 96
Cdd:COG4138 12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLLPGQ-GEILLNGRPLSDWSAAELARHRAYLSQQQSPPFAMPVFQYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 97 NFGrfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ-------DTDYILLDEPLNNLDMK 169
Cdd:COG4138 91 ALH---QPAGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEPMNSLDVA 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 170 HSVQIMQTLRRLCkDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEMDVHIEEIRGQR 246
Cdd:COG4138 168 QQAALDRLLRELC-QQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPENLSEVFGVKFRRLEVEGHR 243
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-215 |
2.68e-40 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 138.79 E-value: 2.68e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLA-- 74
Cdd:cd03257 1 LLEVKNLSVSFPTGggsvKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKir 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 -KKLSILKQTNHTEMN--ITVEQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQL-QSIRHRNIKTLSGGQRQRAYIAMTI 150
Cdd:cd03257 81 rKEIQMVFQDPMSSLNprMTIGEQIAEPLRIHGKLSKKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03257 161 ALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIV 225
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-225 |
4.82e-39 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 135.71 E-value: 4.82e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDL---AKKLS 78
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELyrlRRRMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTEMNITVEQlvNFGrFP-YSKGRMKKEDY-EQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDY 156
Cdd:cd03261 81 MLFQSGALFDSLTVFE--NVA-FPlREHTRLSEEEIrEIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPEL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 157 ILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQ 225
Cdd:cd03261 158 LLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-213 |
6.51e-39 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 133.14 E-value: 6.51e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQ 82
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 83 tnhtemnitveqlvnfgrfpyskgrmkkedyeqveyaldllqlqsirhrniktLSGGQRQRAYIAMTIAQDTDYILLDEP 162
Cdd:cd00267 81 -----------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEP 107
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 807234162 163 LNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGE 213
Cdd:cd00267 108 TSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
15-200 |
7.06e-39 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 133.90 E-value: 7.06e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYknddlakklsiLKQtnHTE----MNI 90
Cdd:NF040873 6 PVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAY-----------VPQ--RSEvpdsLPL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 TVEQLVNFGRFPY--SKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDM 168
Cdd:NF040873 73 TVRDLVAMGRWARrgLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDA 152
|
170 180 190
....*....|....*....|....*....|..
gi 807234162 169 KHSVQIMQTLRRLCKDlNKTIVIVLHDINFAS 200
Cdd:NF040873 153 ESRERIIALLAEEHAR-GATVVVVTHDLELVR 183
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-215 |
8.25e-39 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 135.70 E-value: 8.25e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAI----QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKK 76
Cdd:COG1124 1 MLEVRNLSVSYgqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEMN--ITVEQLVnfgRFPYSKGRMKKEDyEQVEYALDLLQL-QSIRHRNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:COG1124 81 VQMVFQDPYASLHprHTVDRIL---AEPLRIHGLPDRE-ERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILE 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:COG1124 157 PELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIV 218
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-219 |
3.74e-38 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 136.36 E-value: 3.74e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdykNDDLAKKLSIl 80
Cdd:COG3839 3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDV----TDLPPKDRNI- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 kqtnhtEM---------NITVEQlvNFGrFPYSKGRMKKEDYEQ-VEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTI 150
Cdd:COG3839 78 ------AMvfqsyalypHMTVYE--NIA-FPLKLRKVPKAEIDRrVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRAL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADT 219
Cdd:COG3839 149 VREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGT 217
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1-233 |
3.47e-37 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 132.26 E-value: 3.47e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE--------KGTIKIEGKAVVDYKNDD 72
Cdd:PRK13547 1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAIDAPR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 LAKKLSILKQTNHTEMNITVEQLVNFGRFPYSK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTI 150
Cdd:PRK13547 81 LARLRAVLPQAAQPAFAFSAREIVLLGRYPHARraGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 151 AQ---------DTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKD 221
Cdd:PRK13547 161 AQlwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPA 240
|
250
....*....|..
gi 807234162 222 NVIQAEILKQLY 233
Cdd:PRK13547 241 DVLTPAHIARCY 252
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-213 |
3.66e-37 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 129.23 E-value: 3.66e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIlk 81
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPLRRRI-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 qtnhtemnitveQLV--NFGRFPYskgrmkKEDYEQVEYALdllqlqsirhrniktlSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:cd03229 79 ------------GMVfqDFALFPH------LTVLENIALGL----------------SGGQQQRVALARALAMDPDVLLL 124
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGE 213
Cdd:cd03229 125 DEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-214 |
3.99e-37 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 128.67 E-value: 3.99e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKnDDLAKKLSILK 81
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEP-EEVKRRIGYLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQlvnfgrfpyskgrmkkedyeqveyaldllqlqsirhrNIKtLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03230 80 EEPSLYENLTVRE-------------------------------------NLK-LSGGMKQRLALAQALLHDPELLILDE 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:cd03230 122 PTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-216 |
4.63e-37 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 130.28 E-value: 4.63e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDyknddLAKKL 77
Cdd:cd03293 1 LEVRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTG-----PGPDR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILKQtNHTEMN-ITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDY 156
Cdd:cd03293 76 GYVFQ-QDALLPwLTVLDNVALG--LELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDV 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 157 ILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKN--GEIVK 216
Cdd:cd03293 153 LLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRIVA 214
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
2-232 |
1.82e-36 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 130.26 E-value: 1.82e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQ-----NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLA-- 74
Cdd:TIGR04521 1 IKLKNVSYIYQpgtpfEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKdl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 -KKLSILKQtnHTEMNI---TVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQL-QSIRHRNIKTLSGGQRQRAYIAMT 149
Cdd:TIGR04521 81 rKKVGLVFQ--FPEHQLfeeTVYKDIAFG--PKNLGLSEEEAEERVKEALELVGLdEEYLERSPFELSGGQMRRVAIAGV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI-QAEI 228
Cdd:TIGR04521 157 LAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFsDVDE 236
|
....
gi 807234162 229 LKQL 232
Cdd:TIGR04521 237 LEKI 240
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
2-214 |
1.90e-36 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 128.40 E-value: 1.90e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILK 81
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEWRRQVAYVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNH-TEMniTVEQlvNFgRFPYSKgRMKKEDYEQVEYALDLLQLQ-SIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:COG4619 81 QEPAlWGG--TVRD--NL-PFPFQL-RERKFDRERALELLERLGLPpDILDKPVERLSGGERQRLALIRALLLQPDVLLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:COG4619 155 DEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-231 |
2.21e-36 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 128.94 E-value: 2.21e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLA---KKL 77
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYelrRRI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILKQTN--HTEMniTVEQ-----LVNFGRFPyskgrmKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTI 150
Cdd:COG1127 85 GMLFQGGalFDSL--TVFEnvafpLREHTDLS------EAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARAL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQA--EI 228
Cdd:COG1127 157 ALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLASddPW 236
|
...
gi 807234162 229 LKQ 231
Cdd:COG1127 237 VRQ 239
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-214 |
2.82e-36 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 128.03 E-value: 2.82e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKND---------- 71
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNinelrqkvgm 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 72 -----DLAKKLSILKqtNHTEMNITVeqlvnfgrfpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYI 146
Cdd:cd03262 81 vfqqfNLFPHLTVLE--NITLAPIKV------------KGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAI 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 147 AMTIAQDTDYILLDEPLNNLD--MKHSVqiMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:cd03262 147 ARALAMNPKVMLFDEPTSALDpeLVGEV--LDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-242 |
5.39e-36 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 128.28 E-value: 5.39e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVS-----------RLFEYEKGTIKIEgkavvdyk 69
Cdd:COG1119 3 LLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITgdlpptygndvRLFGERRGGEDVW-------- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 70 ndDLAKKLSILKQTNHTEM--NITVEQLVNFGRFPySKGRMKKEDYEQVEYA---LDLLQLQSIRHRNIKTLSGGQRQRA 144
Cdd:COG1119 75 --ELRKRIGLVSPALQLRFprDETVLDVVLSGFFD-SIGLYREPTDEQRERArelLELLGLAHLADRPFGTLSQGEQRRV 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDInfascysDDIIA-------LKNGEIVKA 217
Cdd:COG1119 152 LIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHV-------EEIPPgithvllLKDGRVVAA 224
|
250 260
....*....|....*....|....*
gi 807234162 218 DTKDNVIQAEILKQLYEMDVHIEEI 242
Cdd:COG1119 225 GPKEEVLTSENLSEAFGLPVEVERR 249
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
17-215 |
5.99e-36 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 127.55 E-value: 5.99e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKkLSILK--QTNHTEMNITVEQ 94
Cdd:cd03219 16 LDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIAR-LGIGRtfQIPRLFPELTVLE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGRFPYSKG--------RMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNL 166
Cdd:cd03219 95 NVMVAAQARTGSglllararREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAAGL 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 807234162 167 DMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03219 175 NPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQGRVI 222
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-215 |
1.24e-35 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 126.22 E-value: 1.24e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDlaKKLSILK 81
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD--RDIAMVF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFGRfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03301 79 QNYALYPHMTVYDNIAFGL--KLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03301 157 PLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-219 |
2.06e-35 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 129.45 E-value: 2.06e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdyknDDLAkklsil 80
Cdd:COG3842 5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV-----TGLP------ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 kqTNHTEMNI-----------TVEQLVNFG-RFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAM 148
Cdd:COG3842 74 --PEKRNVGMvfqdyalfphlTVAENVAFGlRM---RGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALAR 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 807234162 149 TIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADT 219
Cdd:COG3842 149 ALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGT 219
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-220 |
2.12e-35 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 125.94 E-value: 2.12e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK---K 76
Cdd:COG2884 1 MIRFENVSKRYPGgREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYlrrR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEMNITVEQLVnfgRFP-----YSKGRMKKedyeQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIA 151
Cdd:COG2884 81 IGVVFQDFRLLPDRTVYENV---ALPlrvtgKSRKEIRR----RVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 152 QDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKdLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTK 220
Cdd:COG2884 154 NRPELLLADEPTGNLDPETSWEIMELLEEINR-RGTTVLIATHDLELVDRMPKRVLELEDGRLVRDEAR 221
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
17-164 |
2.55e-35 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 123.53 E-value: 2.55e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTEMNITVEQLV 96
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 97 NFGRfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNI----KTLSGGQRQRAYIAMTIAQDTDYILLDEPLN 164
Cdd:pfam00005 81 RLGL--LLKGLSKREKDARAEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-216 |
3.46e-35 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 126.36 E-value: 3.46e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdyknDDLAKK 76
Cdd:COG1116 7 ALELRGVSKRFPTGgggvTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPV-----TGPGPD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQtNHTEMN-ITVEQLVNFG-RFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDT 154
Cdd:COG1116 82 RGVVFQ-EPALLPwLTVLDNVALGlEL---RGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDP 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 155 DYILLDEPLNNLD--MKHSVQimQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKN--GEIVK 216
Cdd:COG1116 158 EVLLMDEPFGALDalTRERLQ--DELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSArpGRIVE 221
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-215 |
3.45e-34 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 122.30 E-value: 3.45e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGrLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKnDDLAKKLSILK 81
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQP-QKLRRRIGYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFgrFPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03264 79 QEFGVYPNFTVREFLDY--IAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 162 PLNNLDMKHSVQimqtLRRLCKDL--NKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03264 157 PTAGLDPEERIR----FRNLLSELgeDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
2-213 |
3.94e-34 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 120.95 E-value: 3.94e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQN--KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:cd03228 1 IEFKNVSFSYPGrpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKNIAY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHtemnitveqLVNfgrfpyskgrmkkedyeqveyaldllqlQSIRHrNIktLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:cd03228 81 VPQDPF---------LFS----------------------------GTIRE-NI--LSGGQRQRIAIARALLRDPPILIL 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIVLHDINFASCYsDDIIALKNGE 213
Cdd:cd03228 121 DEATSALDPETEALILEALRALAKG--KTVIVIAHRLSTIRDA-DRIIVLDDGR 171
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-227 |
5.58e-34 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 128.72 E-value: 5.58e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLD-KAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:COG4988 337 IELEDVSfSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQIAWV 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTeMNITVEQLVNFGRFPYSKgrmkkedyEQVEYALDLLQLQSI--------------RHRNiktLSGGQRQRAYI 146
Cdd:COG4988 417 PQNPYL-FAGTIRENLRLGRPDASD--------EELEAALEAAGLDEFvaalpdgldtplgeGGRG---LSGGQAQRLAL 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 147 AMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIV---LHDINFAscysDDIIALKNGEIVKADTKDNV 223
Cdd:COG4988 485 ARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKG--RTVILIthrLALLAQA----DRILVLDDGRIVEQGTHEEL 558
|
....
gi 807234162 224 IQAE 227
Cdd:COG4988 559 LAKN 562
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-219 |
6.75e-34 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 122.35 E-value: 6.75e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVD---YKnddlaKKLS 78
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNlppHK-----RPVN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTEMNITVEQLVNFG-RFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYI 157
Cdd:cd03300 76 TVFQNYALFPHLTVFENIAFGlRL---KKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 158 LLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADT 219
Cdd:cd03300 153 LLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
17-246 |
5.02e-33 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 120.42 E-value: 5.02e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVD---------IQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEkGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTE 87
Cdd:PRK03695 3 LNDVAVStrlgplsaeVRAGEILHLVGPNGAGKSTLLARMAGLLPGS-GSIQFAGQPLEAWSAAELARHRAYLSQQQTPP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 88 MNITVEQLVNFGRfpySKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ-------DTDYILLD 160
Cdd:PRK03695 82 FAMPVFQYLTLHQ---PDKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvwpdinpAGQLLLLD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKdLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEMDVHIE 240
Cdd:PRK03695 159 EPMNSLDVAQQAALDRLLSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENLAQVFGVNFRRL 237
|
....*.
gi 807234162 241 EIRGQR 246
Cdd:PRK03695 238 DVEGHP 243
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-215 |
8.86e-33 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 119.71 E-value: 8.86e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDdlakklsIL 80
Cdd:COG1126 1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKD-------IN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMnitVEQlvNFGRFP-------------YSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIA 147
Cdd:COG1126 74 KLRRKVGM---VFQ--QFNLFPhltvlenvtlapiKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 148 MTIAQDTDYILLDEPLNNLD--MKHSVqiMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:COG1126 149 RALAMEPKVMLFDEPTSALDpeLVGEV--LDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIV 215
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
16-215 |
1.07e-32 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 118.51 E-value: 1.07e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavvDYKNDDLAKKLSILKQT-NHTEMNITVEQ 94
Cdd:cd03226 15 ILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGK---PIKAKERRKSIGYVMQDvDYQLFTDSVRE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGRFPYSKGrmkkedYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQI 174
Cdd:cd03226 92 ELLLGLKELDAG------NEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERV 165
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 807234162 175 MQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03226 166 GELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-215 |
1.23e-32 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 119.09 E-value: 1.23e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPilKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDlaKKLSIL 80
Cdd:COG3840 1 MLRLDDLTYRYGDFP--LRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAE--RPVSML 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFGRFPysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:COG3840 77 FQENNLFPHLTVAQNIGLGLRP--GLKLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLD 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 161 EPLNNLD--MKHsvQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:COG3840 155 EPFSALDpaLRQ--EMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIA 209
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
2-253 |
2.66e-32 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 119.46 E-value: 2.66e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNL-------DKAiqnkpiLKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLA 74
Cdd:PRK13647 5 IEVEDLhfrykdgTKA------LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 KKLSILKQTNHTEM-NITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:PRK13647 79 SKVGLVFQDPDDQVfSSTVWDDVAFG--PVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKAD-----TKDNVIQAEI 228
Cdd:PRK13647 157 PDVIVLDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGdksllTDEDIVEQAG 235
|
250 260 270
....*....|....*....|....*....|
gi 807234162 229 LK-----QLYEmdvHIEEIRGQRICLYYDE 253
Cdd:PRK13647 236 LRlplvaQIFE---DLPELGQSKLPLTVKE 262
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-215 |
4.99e-32 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 117.28 E-value: 4.99e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEK-----GTIKIEGKAVVDYKNDDLAKK 76
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPgapdeGEVLLDGKDIYDLDVDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSI---LKQTNHTEMniTVEQLVNFGRFPYSKGRMKKEDYEqVEYALDLLQL--QSIRHRNIKTLSGGQRQRAYIAMTIA 151
Cdd:cd03260 81 RRVgmvFQKPNPFPG--SIYDNVAYGLRLHGIKLKEELDER-VEEALRKAALwdEVKDRLHALGLSGGQQQRLCLARALA 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 152 QDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03260 158 NEPEVLLLDEPTSALDPISTAKIEELIAELKKEY--TIVIVTHNMQQAARVADRTAFLLNGRLV 219
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-195 |
7.52e-32 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 116.04 E-value: 7.52e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDyKNDDLAKKLSIL 80
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRD-AREDYRRRLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFgrfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:COG4133 81 GHADGLKPELTVRENLRF----WAALYGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLD 156
|
170 180 190
....*....|....*....|....*....|....*.
gi 807234162 161 EPLNNLDmKHSVQ-IMQTLRRLCKDlNKTIVIVLHD 195
Cdd:COG4133 157 EPFTALD-AAGVAlLAELIAAHLAR-GGAVLLTTHQ 190
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-226 |
2.78e-31 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 116.29 E-value: 2.78e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDK---AIQnkpILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAkKL 77
Cdd:COG0411 4 LLEVRGLTKrfgGLV---AVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIA-RL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILK--QTNHTEMNITVEQ--------------LVNFGRFPYSKGRMkKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQR 141
Cdd:COG0411 80 GIARtfQNPRLFPELTVLEnvlvaaharlgrglLAALLRLPRARREE-REARERAEELLERVGLADRADEPAGNLSYGQQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 142 QRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEI------- 214
Cdd:COG0411 159 RRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRViaegtpa 238
|
250
....*....|...
gi 807234162 215 -VKADTKdnVIQA 226
Cdd:COG0411 239 eVRADPR--VIEA 249
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
12-227 |
2.85e-31 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 121.86 E-value: 2.85e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTeMNIT 91
Cdd:COG2274 486 DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRRQIGVVLQDVFL-FSGT 564
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVNFGRFPYskgrmkkeDYEQVEYALDLLQLQS-IR------HRNI----KTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:COG2274 565 IRENITLGDPDA--------TDEEIIEAARLAGLHDfIEalpmgyDTVVgeggSNLSGGQRQRLAIARALLRNPRILILD 636
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQAE 227
Cdd:COG2274 637 EATSALDAETEAIILENLRRLLK--GRTVIIIAHRLSTIR-LADRIIVLDKGRIVEDGTHEELLARK 700
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
2-224 |
5.62e-31 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 114.74 E-value: 5.62e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKpILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDlaKKLSILK 81
Cdd:cd03299 1 LKVENLSKDWKEF-KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEK--RDISYVP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFGRfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03299 78 QNYALFPHMTVYKNIAYGL--KKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDE 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:cd03299 156 PFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVF 218
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1-219 |
6.88e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 115.56 E-value: 6.88e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLD-KAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDDLA---KK 76
Cdd:PRK13639 1 ILETRDLKySYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEP-IKYDKKSLLevrKT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEM-NITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTD 155
Cdd:PRK13639 80 VGIVFQNPDDQLfAPTVEEDVAFG--PLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPE 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 156 YILLDEPLNNLDMKHSVQIMqtlrRLCKDLNK---TIVIVLHDINFASCYSDDIIALKNGEIVKADT 219
Cdd:PRK13639 158 IIVLDEPTSGLDPMGASQIM----KLLYDLNKegiTIIISTHDVDLVPVYADKVYVMSDGKIIKEGT 220
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-223 |
9.12e-31 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 114.36 E-value: 9.12e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDlaKKLSILK 81
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE--RNVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFG-RFPYSKGRMKKEDY-EQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:cd03296 81 QHYALFRHMTVFDNVAFGlRVKPRSERPPEAEIrAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV 223
Cdd:cd03296 161 DEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEV 224
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
12-234 |
1.07e-30 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 119.49 E-value: 1.07e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTeMNIT 91
Cdd:COG4987 346 AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRRIAVVPQRPHL-FDTT 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQlvNFgrfpyskgRMKKEDY--EQVEYALDLLQLQSIRHRNIK-----------TLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:COG4987 425 LRE--NL--------RLARPDAtdEELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILL 494
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQAE-ILKQLYE 234
Cdd:COG4987 495 LDEPTEGLDAATEQALLADLLEALAG--RTVLLITHRLAGLE-RMDRILVLEDGRIVEQGTHEELLAQNgRYRQLYQ 568
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
1-226 |
1.74e-30 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 115.19 E-value: 1.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLakKLSI 79
Cdd:COG1125 1 MIEFENVTKRYPDgTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVEL--RRRI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 ---LKQT----NHT-EMNI-TVEQLVNfgrfpYSKGRMKkedyEQVEYALDLLQL--QSIRHRNIKTLSGGQRQRAYIAM 148
Cdd:COG1125 79 gyvIQQIglfpHMTvAENIaTVPRLLG-----WDKERIR----ARVDELLELVGLdpEEYRDRYPHELSGGQQQRVGVAR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 149 TIAQDTDYILLDEPLNNLD--MKHSVQimQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQA 226
Cdd:COG1125 150 ALAADPPILLMDEPFGALDpiTREQLQ--DELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILAN 227
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
2-215 |
2.47e-30 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 112.60 E-value: 2.47e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQN--KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVdYKNDDLAKKLSI 79
Cdd:cd03263 1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIR-TDRKAARQSLGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTEMNITVEQLVNF-GRFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:cd03263 80 CPQFDALFDELTVREHLRFyARL---KGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03263 157 LDEPTSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLR 211
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
2-223 |
3.70e-30 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 115.24 E-value: 3.70e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVdyknddlakklsilk 81
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLF--------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 qTNHT--EMNI-------------TVEQLVNFG--RFPYSKGRMKkedyEQVEYALDLLQLQSIRHRNIKTLSGGQRQRA 144
Cdd:COG1118 68 -TNLPprERRVgfvfqhyalfphmTVAENIAFGlrVRPPSKAEIR----ARVEELLELVQLEGLADRYPSQLSGGQRQRV 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV 223
Cdd:COG1118 143 ALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEV 221
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-223 |
4.34e-30 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 112.14 E-value: 4.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKK-LSIL 80
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAgIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQlvNF--GRFPYSKGRmKKEDYEQVeyaLDLL-QLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYI 157
Cdd:cd03224 81 PEGRRIFPELTVEE--NLllGAYARRRAK-RKARLERV---YELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 158 LLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV 223
Cdd:cd03224 155 LLDEPSEGLAPKIVEEIFEAIREL-RDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
2-225 |
5.54e-30 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 113.58 E-value: 5.54e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQ-NKPI----LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKND----D 72
Cdd:PRK13634 3 ITFQKVEHRYQyKTPFerraLYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKNkklkP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 LAKKLSILKQ-TNHTEMNITVEQLVNFGrfPYSKGrMKKEDYEQ-VEYALDLLQL-QSIRHRNIKTLSGGQRQRAYIAMT 149
Cdd:PRK13634 83 LRKKVGIVFQfPEHQLFEETVEKDICFG--PMNFG-VSEEDAKQkAREMIELVGLpEELLARSPFELSGGQMRRVAIAGV 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQ 225
Cdd:PRK13634 160 LAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFA 235
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
4-214 |
1.09e-29 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 114.36 E-value: 1.09e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 4 IKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdykNDDLAKKLSI--LK 81
Cdd:PRK11000 6 LRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRM----NDVPPAERGVgmVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFGRfpysK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:PRK11000 82 QSYALYPHLSVAENMSFGL----KlaGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:PRK11000 158 DEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRV 212
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
2-214 |
1.61e-29 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 110.58 E-value: 1.61e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNK-PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK---KL 77
Cdd:cd03292 1 IEFINVTKTYPNGtAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYlrrKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILKQTNHTEMNITVEQLVNFG-RFPYSKGRmkkEDYEQVEYALDLLQLQSiRHRNIKT-LSGGQRQRAYIAMTIAQDTD 155
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFAlEVTGVPPR---EIRKRVPAALELVGLSH-KHRALPAeLSGGEQQRVAIARAIVNSPT 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 156 YILLDEPLNNLDMKHSVQIMqtlrRLCKDLNK---TIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:cd03292 157 ILIADEPTGNLDPDTTWEIM----NLLKKINKagtTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
12-219 |
2.20e-29 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 111.65 E-value: 2.20e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTE-MNI 90
Cdd:PRK13635 18 AATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRRQVGMVFQNPDNQfVGA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 TVEQLVNFGRfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKH 170
Cdd:PRK13635 98 TVQDDVAFGL--ENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRG 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 807234162 171 SVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEIVKADT 219
Cdd:PRK13635 176 RREVLETVRQLKEQKGITVLSITHDLDEAA-QADRVIVMNKGEILEEGT 223
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
19-218 |
3.47e-29 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 109.69 E-value: 3.47e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 19 NINVDIQK--------------GRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDY-KNDDLA---KKLSIL 80
Cdd:cd03297 1 MLCVDIEKrlpdftlkidfdlnEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSrKKINLPpqqRKIGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFGrfpySKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:cd03297 81 FQQYALFPHLNVRENLAFG----LKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKAD 218
Cdd:cd03297 157 EPFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-214 |
4.99e-29 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 112.73 E-value: 4.99e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdykNDDLAKKlsilK 81
Cdd:PRK09452 15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI----THVPAEN----R 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTN----------HtemnITVEQLVNFGRfpyskgRMKK----EDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIA 147
Cdd:PRK09452 87 HVNtvfqsyalfpH----MTVFENVAFGL------RMQKtpaaEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 148 MTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:PRK09452 157 RAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRI 223
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-214 |
5.62e-29 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 109.80 E-value: 5.62e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDD--LAKKLS 78
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDErlIRQEAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTEMNITVEQLVNFGrfPYSKGRMKKEDYEQVeyALDLLQ---LQSIRHRNIKTLSGGQRQRAYIAMTIAQDTD 155
Cdd:PRK09493 81 MVFQQFYLFPHLTALENVMFG--PLRVRGASKEEAEKQ--ARELLAkvgLAERAHHYPSELSGGQQQRVAIARALAVKPK 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 156 YILLDEPLNNLD--MKHSV-QIMQTLrrlcKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:PRK09493 157 LMLFDEPTSALDpeLRHEVlKVMQDL----AEEGMTMVIVTHEIGFAEKVASRLIFIDKGRI 214
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
14-233 |
7.55e-29 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 109.24 E-value: 7.55e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTeMNITVE 93
Cdd:cd03251 15 PPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRRQIGLVSQDVFL-FNDTVA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 94 QLVNFGRFpyskgrmkKEDYEQVEYALDLLQLQS------------IRHRNIKtLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03251 94 ENIAYGRP--------GATREEVEEAARAANAHEfimelpegydtvIGERGVK-LSGGQRQRIAIARALLKDPPILILDE 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLH---DINFAscysDDIIALKNGEIVKADTKDNVIQAE-ILKQLY 233
Cdd:cd03251 165 ATSALDTESERLVQAALERLMK--NRTTFVIAHrlsTIENA----DRIVVLEDGKIVERGTHEELLAQGgVYAKLH 234
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-215 |
1.42e-28 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 107.69 E-value: 1.42e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVdyKNDDLAKKLSILK 81
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQ--KNIEALRRIGALI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNIT-VEQLVNFGRFPyskgRMKKEDYEQVeyaLDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:cd03268 79 EAPGFYPNLTaRENLRLLARLL----GIRKKRIDEV---LDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILD 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03268 152 EPTNGLDPDGIKELRELILSL-RDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
22-215 |
3.60e-28 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 106.81 E-value: 3.60e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 22 VDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGkavVDYKNDDLAKK-LSILKQTNHTEMNITVEQLVNFGR 100
Cdd:cd03298 19 LTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLING---VDVTAAPPADRpVSMLFQENNLFAHLTVEQNVGLGL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 101 FPysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRR 180
Cdd:cd03298 96 SP--GLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLD 173
|
170 180 190
....*....|....*....|....*....|....*
gi 807234162 181 LCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03298 174 LHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIA 208
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
17-233 |
3.63e-28 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 108.43 E-value: 3.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdykNDDLAKKL-SILKQTNHTEMN--ITVE 93
Cdd:PRK15056 23 LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPT----RQALQKNLvAYVPQSEEVDWSfpVLVE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 94 QLVNFGRFPYSK--GRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHS 171
Cdd:PRK15056 99 DVVMMGRYGHMGwlRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTE 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 172 VQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKnGEIVKADTKDNVIQAEILKQLY 233
Cdd:PRK15056 179 ARIISLLREL-RDEGKTMLVSTHNLGSVTEFCDYTVMVK-GTVLASGPTETTFTAENLELAF 238
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
1-213 |
4.94e-28 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 106.56 E-value: 4.94e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQ-NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK---K 76
Cdd:TIGR02673 1 MIEFHNVSKAYPgGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLPLlrrR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEMNITVEQLVnfgRFPYSKGRMKKEDYE-QVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTD 155
Cdd:TIGR02673 81 IGVVFQDFRLLPDRTVYENV---ALPLEVRGKKEREIQrRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 156 YILLDEPLNNLDMKHSVQIMQTLRRLCKdLNKTIVIVLHDINFASCYSDDIIALKNGE 213
Cdd:TIGR02673 158 LLLADEPTGNLDPDLSERILDLLKRLNK-RGTTVIVATHDLSLVDRVAHRVIILDDGR 214
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
17-215 |
5.14e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 108.40 E-value: 5.14e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvDYKND---DLAKKLSILKQT-NHTEMNITV 92
Cdd:PRK13636 22 LKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPI-DYSRKglmKLRESVGMVFQDpDNQLFSASV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSV 172
Cdd:PRK13636 101 YQDVSFG--AVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVS 178
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 807234162 173 QIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK13636 179 EIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVI 221
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
13-215 |
5.71e-28 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 111.80 E-value: 5.71e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNH------T 86
Cdd:COG1132 352 DRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQIGVVPQDTFlfsgtiR 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 87 EmNITveqlvnFGRFPYSKgrmkkedyEQVEYALDLLQLqsirHRNIK---------------TLSGGQRQRAYIAMTIA 151
Cdd:COG1132 432 E-NIR------YGRPDATD--------EEVEEAAKAAQA----HEFIEalpdgydtvvgergvNLSGGQRQRIAIARALL 492
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 152 QDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIV---LHDINFAscysDDIIALKNGEIV 215
Cdd:COG1132 493 KDPPILILDEATSALDTETEALIQEALERLMKG--RTTIVIahrLSTIRNA----DRILVLDDGRIV 553
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-215 |
6.63e-28 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 106.21 E-value: 6.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDD--------- 72
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNRigylpeerg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 LAKKLSILkqtnhtemnitvEQLVNFGRFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:cd03269 81 LYPKMKVI------------DQLVYLAQL---KGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIH 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 153 DTDYILLDEPLNNLDmKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03269 146 DPELLILDEPFSGLD-PVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-216 |
7.36e-28 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 106.51 E-value: 7.36e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDL--- 73
Cdd:cd03258 1 MIELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELrka 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 74 AKKLSILKQTNHTEMNITVEQLVnfgRFPYSKGRM-KKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:cd03258 81 RRRIGMIFQHFNLLSSRTVFENV---ALPLEIAGVpKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALAN 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:cd03258 158 NPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVE 221
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-219 |
1.35e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 107.12 E-value: 1.35e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLD---KAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKL 77
Cdd:PRK13650 4 IIEVKNLTfkyKEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRHKI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILKQTNHTE-MNITVEQLVNFGRfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDY 156
Cdd:PRK13650 84 GMVFQNPDNQfVGATVEDDVAFGL--ENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKI 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 157 ILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEIVKADT 219
Cdd:PRK13650 162 IILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTST 223
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-241 |
1.41e-27 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 106.64 E-value: 1.41e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKG----------TIKIEGKAVVDYKN 70
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSagshiellgrTVQREGRLARDIRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 71 DDlAKKLSILKQTNHTEMNITVEQLV--NFGRFPYSKGRMKKEDYEQVEYALDLLQ---LQSIRHRNIKTLSGGQRQRAY 145
Cdd:PRK09984 84 SR-ANTGYIFQQFNLVNRLSVLENVLigALGSTPFWRTCFSWFTREQKQRALQALTrvgMVHFAHQRVSTLSGGQQQRVA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 146 IAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVkADTKDNVIQ 225
Cdd:PRK09984 163 IARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVF-YDGSSQQFD 241
|
250
....*....|....*.
gi 807234162 226 AEILKQLYEMDVHIEE 241
Cdd:PRK09984 242 NERFDHLYRSINRVEE 257
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
16-215 |
1.62e-27 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 105.43 E-value: 1.62e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEK---GTIKIEGKAVvdyKNDDLAKKLSILKQTNHTEMNITV 92
Cdd:cd03234 22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQPR---KPDQFQKCVAYVRQDDILLPGLTV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNF-----GRFPYSKGRMKKEDyeqVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLD 167
Cdd:cd03234 99 RETLTYtailrLPRKSSDAIRKKRV---EDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 168 MKHSVQIMQTLRRLCKDlNKTIVIVLH----DInfascYS--DDIIALKNGEIV 215
Cdd:cd03234 176 SFTALNLVSTLSQLARR-NRIVILTIHqprsDL-----FRlfDRILLLSSGEIV 223
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-215 |
2.83e-27 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 104.76 E-value: 2.83e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKP----ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKk 76
Cdd:cd03266 1 MITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEARRR- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEMNITV-EQLVNFGRFPYSKGRmkkEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTD 155
Cdd:cd03266 80 LGFVSDSTGLYDRLTArENLEYFAGLYGLKGD---ELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 156 YILLDEPLNNLDMKHSVQIMQTLRRLCkDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03266 157 VLLLDEPTTGLDVMATRALREFIRQLR-ALGKCILFSTHIMQEVERLCDRVVVLHRGRVV 215
|
|
| anch_rpt_ABC |
TIGR03771 |
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ... |
26-233 |
2.84e-27 |
|
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 104.93 E-value: 2.84e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 26 KGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvvdykNDDLAKKLSILKQTNHT--EMNITVEQLVNFGRfpy 103
Cdd:TIGR03771 5 KGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGAS-----PGKGWRHIGYVPQRHEFawDFPISVAHTVMSGR--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 104 sKGRM------KKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQT 177
Cdd:TIGR03771 77 -TGHIgwlrrpCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQELLTEL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 178 LRRLCKDLNkTIVIVLHDINFASCYSDDIIaLKNGEIVKADTKDNVIQAEILKQLY 233
Cdd:TIGR03771 156 FIELAGAGT-AILMTTHDLAQAMATCDRVV-LLNGRVIADGTPQQLQDPAPWMTTF 209
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
14-215 |
3.88e-27 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 103.40 E-value: 3.88e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVS--RLFEYEKGTIKIEGKAVvdyKNDDLAKKLSILKQTNHTEMNIT 91
Cdd:cd03213 22 KQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgrRTGLGVSGEVLINGRPL---DKRSFRKIIGYVPQDDILHPTLT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VeqlvnfgrfpyskgrmkkedYEQVEYALdllqlqsirhrNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHS 171
Cdd:cd03213 99 V--------------------RETLMFAA-----------KLRGLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSA 147
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 807234162 172 VQIMQTLRRLCKDlNKTIVIVLH---DINFASCysDDIIALKNGEIV 215
Cdd:cd03213 148 LQVMSLLRRLADT-GRTIICSIHqpsSEIFELF--DKLLLLSQGRVI 191
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
17-229 |
4.85e-27 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 105.42 E-value: 4.85e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDL----AKKLSILKQtnhtemnitv 92
Cdd:cd03294 40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELrelrRKKISMVFQ---------- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 eqlvNFGRFPYS------------KGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:cd03294 110 ----SFALLPHRtvlenvafglevQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMD 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDnviqaEIL 229
Cdd:cd03294 186 EAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPE-----EIL 249
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-233 |
5.19e-27 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 104.29 E-value: 5.19e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKK-LSI 79
Cdd:COG0410 3 MLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLgIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTEMNITVEQlvNF--GRFPYSKGRMKKEDYEQVeyaLDLL-QLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDY 156
Cdd:COG0410 83 VPEGRRIFPSLTVEE--NLllGAYARRDRAEVRADLERV---YELFpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 157 ILLDEPlnnldmkhS-------V-QIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEI 228
Cdd:COG0410 158 LLLDEP--------SlglapliVeEIFEIIRRL-NREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLADPE 228
|
....*
gi 807234162 229 LKQLY 233
Cdd:COG0410 229 VREAY 233
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
13-215 |
8.73e-27 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 103.85 E-value: 8.73e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQtNHTEMNITV 92
Cdd:cd03253 13 GRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRAIGVVPQ-DTVLFNDTI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNFGRFPYSKgrmkkedyEQVEYALDLLQLqsirHRNIKT---------------LSGGQRQRAYIAMTIAQDTDYI 157
Cdd:cd03253 92 GYNIRYGRPDATD--------EEVIEAAKAAQI----HDKIMRfpdgydtivgerglkLSGGEKQRVAIARAILKNPPIL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 158 LLDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFAScYSDDIIALKNGEIV 215
Cdd:cd03253 160 LLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIV-NADKIIVLKDGRIV 214
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-231 |
1.37e-26 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 104.32 E-value: 1.37e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:PRK13638 1 MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLALRQQVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 -------KQTNHTEMNITVE-QLVNFGRfpyskgrMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:PRK13638 81 tvfqdpeQQIFYTDIDSDIAfSLRNLGV-------PEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKtIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI-QAEILKQ 231
Cdd:PRK13638 154 QARYLLLDEPTAGLDPAGRTQMIAIIRRIVAQGNH-VIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFaCTEAMEQ 232
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-216 |
1.44e-26 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 103.68 E-value: 1.44e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIeGKAVVDyKNDDLAKKLSIL 80
Cdd:PRK11264 3 AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRV-GDITID-TARSLSQQKGLI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQtnhtemnitVEQLV-----NFGRFPYSKGR---------MKKEDYEQ-VEYALDLLQ---LQSIRHRNIKTLSGGQRQ 142
Cdd:PRK11264 81 RQ---------LRQHVgfvfqNFNLFPHRTVLeniiegpviVKGEPKEEaTARARELLAkvgLAGKETSYPRRLSGGQQQ 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 143 RAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:PRK11264 152 RVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGRIVE 224
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-196 |
3.92e-26 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 102.63 E-value: 3.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNL----DKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAV--------VDY 68
Cdd:COG4525 3 MLTVRHVsvryPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVtgpgadrgVVF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 69 KNDDLAKKLSILkqTNhtemnitveqlVNFG-RFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIA 147
Cdd:COG4525 83 QKDALLPWLNVL--DN-----------VAFGlRL---RGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIA 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 807234162 148 MTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDI 196
Cdd:COG4525 147 RALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSV 195
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
15-235 |
4.13e-26 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 106.72 E-value: 4.13e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQtNHTEMNITVEQ 94
Cdd:TIGR02203 346 PALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRRQVALVSQ-DVVLFNDTIAN 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGRfPYSKGRMKKEDYEQVEYALDL-----LQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMK 169
Cdd:TIGR02203 425 NIAYGR-TEQADRAEIERALAAAYAQDFvdklpLGLDTPIGENGVLLSGGQRQRLAIARALLKDAPILILDEATSALDNE 503
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 170 HSVQIMQTLRRLCKdlNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQAEIL-KQLYEM 235
Cdd:TIGR02203 504 SERLVQAALERLMQ--GRTTLVIAHRLSTIE-KADRIVVMDDGRIVERGTHNELLARNGLyAQLHNM 567
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
2-222 |
8.12e-26 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 100.91 E-value: 8.12e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDyKNDDLAKKLSILK 81
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVR-EPREVRRRIGIVF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNIT-VEQLVNFGRFPYSKGRMKKEDYEQVeyaLDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:cd03265 80 QDLSVDDELTgWENLYIHARLYGVPGAERRERIDEL---LDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLD 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDN 222
Cdd:cd03265 157 EPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEE 218
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-216 |
8.81e-26 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 101.53 E-value: 8.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFE-YEKGtiKIEGKAVVD----YKND--DLA 74
Cdd:PRK14247 4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElYPEA--RVSGEVYLDgqdiFKMDviELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 KKLSILKQTNHTEMNITVEQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQL-QSIRHR---NIKTLSGGQRQRAYIAMTI 150
Cdd:PRK14247 82 RRVQMVFQIPNPIPNLSIFENVALGLKLNRLVKSKKELQERVRWALEKAQLwDEVKDRldaPAGKLSGGQQQRLCIARAL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:PRK14247 162 AFQPEVLLADEPTANLDPENTAKIESLFLELKKDM--TIVLVTHFPQQAARISDYVAFLYKGQIVE 225
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
2-223 |
1.08e-25 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 103.24 E-value: 1.08e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDlaKKLSILK 81
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD--RKVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFGR--FPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:PRK10851 81 QHYALFRHMTVFDNIAFGLtvLPRRERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV 223
Cdd:PRK10851 161 DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQV 224
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
2-213 |
1.53e-25 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 99.47 E-value: 1.53e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNL-----DKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVsrLFEYEKgtikIEGKAVVdyknddlAKK 76
Cdd:cd03250 1 ISVEDAsftwdSGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSAL--LGELEK----LSGSVSV-------PGS 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTeMNITVEQLVNFGRfpyskgRMKKEDYEQVeyaLDLLQLQS------------IRHRNIkTLSGGQRQRA 144
Cdd:cd03250 68 IAYVSQEPWI-QNGTIRENILFGK------PFDEERYEKV---IKACALEPdleilpdgdlteIGEKGI-NLSGGQKQRI 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLrrLCKDL--NKTIVIVLHDINFAScYSDDIIALKNGE 213
Cdd:cd03250 137 SLARAVYSDADIYLLDDPLSAVDAHVGRHIFENC--ILGLLlnNKTRILVTHQLQLLP-HADQIVVLDNGR 204
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-255 |
2.32e-25 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 101.34 E-value: 2.32e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDD-------- 72
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEP-LDPEDRRrigylpee 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 --LAKKLSILkqtnhtemnitvEQLVNFGRFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTI 150
Cdd:COG4152 80 rgLYPKMKVG------------EQLVYLARL---KGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAAL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 151 AQDTDYILLDEPLNNLDmKHSVQIM-QTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV--------KADTKD 221
Cdd:COG4152 145 LHDPELLILDEPFSGLD-PVNVELLkDVIREL-AAKGTTVIFSSHQMELVEELCDRIVIINKGRKVlsgsvdeiRRQFGR 222
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 807234162 222 NVI------QAEILKQLYEmdVHIEEIRGQRICLYYDEDT 255
Cdd:COG4152 223 NTLrleadgDAGWLRALPG--VTVVEEDGDGAELKLEDGA 260
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-218 |
2.44e-25 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 100.50 E-value: 2.44e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTiKIEGKavVDYKNDDLAKKlsilk 81
Cdd:COG1117 12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLIPGA-RVEGE--ILLDGEDIYDP----- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 qtnhtemNITVEQL------VnFGR---FPYS-----------KGRMKKEDYEQ-VEYAL----------DLLqlqsirH 130
Cdd:COG1117 84 -------DVDVVELrrrvgmV-FQKpnpFPKSiydnvayglrlHGIKSKSELDEiVEESLrkaalwdevkDRL------K 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 131 RNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSDDIIALK 210
Cdd:COG1117 150 KSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDY--TIVIVTHNMQQAARVSDYTAFFY 227
|
....*...
gi 807234162 211 NGEIVKAD 218
Cdd:COG1117 228 LGELVEFG 235
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
1-197 |
2.64e-25 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 99.09 E-value: 2.64e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAV----SRLFEYEkGTIKIEGKAVvdyknDDL--- 73
Cdd:COG4136 1 MLSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIagtlSPAFSAS-GEVLLNGRRL-----TALpae 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 74 AKKLSILKQTNHTEMNITVEQLVNFGrFPYSKGRMKKEDyeQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:COG4136 75 QRRIGILFQDDLLFPHLSVGENLAFA-LPPTIGRAQRRA--RVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAE 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 807234162 154 TDYILLDEPLNNLDMKHSVQImqtlRRLC----KDLNKTIVIVLHDIN 197
Cdd:COG4136 152 PRALLLDEPFSKLDAALRAQF----REFVfeqiRQRGIPALLVTHDEE 195
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-232 |
4.09e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 100.45 E-value: 4.09e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDY-KNDDLAKKLS 78
Cdd:PRK13644 1 MIRLENVSYSYPDgTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFsKLQGIRKLVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTE-MNITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYI 157
Cdd:PRK13644 81 IVFQNPETQfVGRTVEEDLAFG--PENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 158 LLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCySDDIIALKNGEIVKADTKDNVIQAEILKQL 232
Cdd:PRK13644 159 IFDEVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEPENVLSDVSLQTL 231
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-216 |
7.17e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 99.68 E-value: 7.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNL--DKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLS 78
Cdd:PRK13632 7 MIKVENVsfSYPNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIRKKIG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTE-MNITVEQLVNFG----RFPYSKGRMKKEDYEQVEYALDLLQlqsirhRNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:PRK13632 87 IIFQNPDNQfIGATVEDDIAFGlenkKVPPKKMKDIIDDLAKKVGMEDYLD------KEPQNLSGGQKQRVAIASVLALN 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAsCYSDDIIALKNGEIVK 216
Cdd:PRK13632 161 PEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIA 222
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
2-209 |
1.22e-24 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 101.98 E-value: 1.22e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNK-PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:TIGR02857 322 LEFSGVSVAYPGRrPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTeMNITVEQLVNFGRfPYSKGRMKKEDYEQVeYALDLLQ-----LQSIRHRNIKTLSGGQRQRAYIAMTIAQDTD 155
Cdd:TIGR02857 402 PQHPFL-FAGTIAENIRLAR-PDASDAEIREALERA-GLDEFVAalpqgLDTPIGEGGAGLSGGQAQRLALARAFLRDAP 478
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 156 YILLDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFASCYsDDIIAL 209
Cdd:TIGR02857 479 LLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALA-DRIVVL 529
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
17-215 |
3.23e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 98.31 E-value: 3.23e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDD----LAKKLSILKQTNHTEM-NIT 91
Cdd:PRK13646 23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKyirpVRKRIGMVFQFPESQLfEDT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVNFGRFPYskgrmkKEDYEQV-EYALDLLqLQSIRHRNIKTLS-----GGQRQRAYIAMTIAQDTDYILLDEPLNN 165
Cdd:PRK13646 103 VEREIIFGPKNF------KMNLDEVkNYAHRLL-MDLGFSRDVMSQSpfqmsGGQMRKIAIVSILAMNPDIIVLDEPTAG 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 807234162 166 LDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK13646 176 LDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIV 225
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
1-216 |
3.33e-24 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 96.65 E-value: 3.33e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKP----ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK- 75
Cdd:TIGR02211 1 LLKCENLGKRYQEGKldtrVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERAKl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 ---KLSILKQTNHTEMNITVEQLVnfgRFPYSKGRMKKEDYEQVEYALdlLQLQSIRHRNIK---TLSGGQRQRAYIAMT 149
Cdd:TIGR02211 81 rnkKLGFIYQFHHLLPDFTALENV---AMPLLIGKKSVKEAKERAYEM--LEKVGLEHRINHrpsELSGGERQRVAIARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYsDDIIALKNGEIVK 216
Cdd:TIGR02211 156 LVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKL-DRVLEMKDGQLFN 221
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
32-219 |
3.41e-24 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 98.72 E-value: 3.41e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 32 LIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDlaKKLSILKQTNHTEMNITVEQLVNFGRfpyskgRMKKE 111
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHL--RHINMVFQSYALFPHMTVEENVAFGL------KMRKV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 112 DYEQ----VEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNK 187
Cdd:TIGR01187 73 PRAEikprVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGI 152
|
170 180 190
....*....|....*....|....*....|..
gi 807234162 188 TIVIVLHDINFASCYSDDIIALKNGEIVKADT 219
Cdd:TIGR01187 153 TFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGT 184
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1-212 |
3.51e-24 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 97.46 E-value: 3.51e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAV--------VDYKNDD 72
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVegpgaergVVFQNEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 LAKKLSILKQtnhtemnitveqlVNFGRFPYSKGRMKKEDYEQveYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:PRK11248 81 LLPWRNVQDN-------------VAFGLQLAGVEKMQRLEIAH--QMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAA 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNG 212
Cdd:PRK11248 146 NPQLLLLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPG 205
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-213 |
3.59e-24 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 94.44 E-value: 3.59e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYknddlakklsilk 81
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVKIGY------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 qtnhtemnitveqlvnfgrfpyskgrmkkedYEQveyaldllqlqsirhrniktLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03221 68 -------------------------------FEQ--------------------LSGGEKMRLALAKLLLENPNLLLLDE 96
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 807234162 162 PLNNLDMKHSVQIMQTLrrlcKDLNKTIVIVLHDINFASCYSDDIIALKNGE 213
Cdd:cd03221 97 PTNHLDLESIEALEEAL----KEYPGTVILVSHDRYFLDQVATKIIELEDGK 144
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
21-214 |
3.72e-24 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 96.47 E-value: 3.72e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 21 NVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVdyKNDDLAKKLSILKQTNHTEMNITVEQLVNFGR 100
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHT--GLAPYQRPVSMLFQENNLFAHLTVRQNIGLGL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 101 FPYSKgrMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRR 180
Cdd:TIGR01277 96 HPGLK--LNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQ 173
|
170 180 190
....*....|....*....|....*....|....
gi 807234162 181 LCKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:TIGR01277 174 LCSERQRTLLMVTHHLSDARAIASQIAVVSQGKI 207
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-233 |
5.47e-24 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 96.46 E-value: 5.47e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKK-LSIL 80
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLgIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQ--LVNFGRFPYSKgrmkKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:cd03218 81 PQEASIFRKLTVEEniLAVLEIRGLSK----KEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 159 LDEPLNNLDMKhSVQIMQTLRRLCKDLNKTIVIVLHDIN--FASCysDDIIALKNGEIVKADTKDNVIQAEILKQLY 233
Cdd:cd03218 157 LDEPFAGVDPI-AVQDIQKIIKILKDRGIGVLITDHNVRetLSIT--DRAYIIYEGKVLAEGTPEEIAANELVRKVY 230
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
13-212 |
6.68e-24 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 95.86 E-value: 6.68e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVsrLFEYEKgtikIEGKAVVDYKNDDLAKKLSILKQTNHTE----- 87
Cdd:cd03290 13 GLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAI--LGEMQT----LEGKVHWSNKNESEPSFEATRSRNRYSVayaaq 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 88 ----MNITVEQLVNFGRfPYSKGRMKK-EDYEQVEYALDLLQL---QSIRHRNIkTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:cd03290 87 kpwlLNATVEENITFGS-PFNKQRYKAvTDACSLQPDIDLLPFgdqTEIGERGI-NLSGGQRQRICVARALYQNTNIVFL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 160 DEPLNNLDMKHSVQIMQT-LRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNG 212
Cdd:cd03290 165 DDPFSALDIHLSDHLMQEgILKFLQDDKRTLVLVTHKLQYLP-HADWIIAMKDG 217
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
17-212 |
6.77e-24 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 96.00 E-value: 6.77e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLA--KKLSILKQtnhtemnITVEQ 94
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRMVvfQNYSLLPW-------LTVRE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGRFPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQI 174
Cdd:TIGR01184 74 NIALAVDRVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNL 153
|
170 180 190
....*....|....*....|....*....|....*...
gi 807234162 175 MQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNG 212
Cdd:TIGR01184 154 QEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-195 |
1.69e-23 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 97.22 E-value: 1.69e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK-PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAV--VDYKNDDLAkkl 77
Cdd:PRK11650 3 GLKLQAVRKSYDGKtQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVneLEPADRDIA--- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 silkqtnhteM---------NITVEQlvNFGrfpYS-KGR-MKKEDYEQ-VEYALDLLQLQSIRHRNIKTLSGGQRQRay 145
Cdd:PRK11650 80 ----------MvfqnyalypHMSVRE--NMA---YGlKIRgMPKAEIEErVAEAARILELEPLLDRKPRELSGGQRQR-- 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 807234162 146 IAM--TIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHD 195
Cdd:PRK11650 143 VAMgrAIVREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHD 194
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
2-235 |
2.09e-23 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 98.94 E-value: 2.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNK--PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:PRK11176 342 IEFRNVTFTYPGKevPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLRNQVAL 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTeMNITVEQLVNFGRfpysKGRMKKEDYEQ---VEYALDLLQ-----LQSIRHRNIKTLSGGQRQRAYIAMTIA 151
Cdd:PRK11176 422 VSQNVHL-FNDTIANNIAYAR----TEQYSREQIEEaarMAYAMDFINkmdngLDTVIGENGVLLSGGQRQRIAIARALL 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 152 QDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVI-QAEILK 230
Cdd:PRK11176 497 RDSPILILDEATSALDTESERAIQAALDELQK--NRTSLVIAHRLSTIE-KADEILVVEDGEIVERGTHAELLaQNGVYA 573
|
....*
gi 807234162 231 QLYEM 235
Cdd:PRK11176 574 QLHKM 578
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
2-219 |
2.47e-23 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 96.71 E-value: 2.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVD--YKNDDLAkklsI 79
Cdd:PRK11432 7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHrsIQQRDIC----M 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTEMNITVEQLVNFGRfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:PRK11432 83 VFQSYALFPHMSLGENVGYGL--KMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADT 219
Cdd:PRK11432 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGS 220
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-232 |
3.25e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 95.15 E-value: 3.25e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNL------DKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKND-DL 73
Cdd:PRK13633 4 MIKCKNVsykyesNEESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLwDI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 74 AKKLSILKQTNHTEMNIT-VEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:PRK13633 84 RNKAGMVFQNPDNQIVATiVEEDVAFG--PENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVI-QAEILKQ 231
Cdd:PRK13633 162 RPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAV-EADRIIVMDSGKVVMEGTPKEIFkEVEMMKK 240
|
.
gi 807234162 232 L 232
Cdd:PRK13633 241 I 241
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
3-232 |
4.22e-23 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 93.74 E-value: 4.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKK-LSILK 81
Cdd:TIGR03410 2 EVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERARAgIAYVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQ--LVNFGRFPYSKGRMKKEDYEQVEYaldllqLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:TIGR03410 82 QGREIFPRLTVEEnlLTGLAALPRRSRKIPDEIYELFPV------LKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 160 DEPLNNLdmKHSV--QIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQL 232
Cdd:TIGR03410 156 DEPTEGI--QPSIikDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDELDEDKVRRYL 228
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
2-225 |
8.08e-23 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 93.06 E-value: 8.08e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLD-KAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:cd03254 3 IEFENVNfSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTeMNITVEQLVNFGRfPYSKGrmkkedyEQVEYALDLLQLQS-IRHR----------NIKTLSGGQRQRAYIAMT 149
Cdd:cd03254 83 LQDTFL-FSGTIMENIRLGR-PNATD-------EEVIEAAKEAGAHDfIMKLpngydtvlgeNGGNLSQGERQLLAIARA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQ 225
Cdd:cd03254 154 MLRDPKILILDEATSNIDTETEKLIQEALEKLMK--GRTSIIIAHRLSTIK-NADKILVLDDGKIIEEGTHDELLA 226
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-215 |
2.04e-22 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 90.18 E-value: 2.04e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDDLAKKLSILk 81
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKE-VSFASPRDARRAGIA- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 qtnhtemniTVEQlvnfgrfpyskgrmkkedyeqveyaldllqlqsirhrniktLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03216 79 ---------MVYQ-----------------------------------------LSVGERQMVEIARALARNARLLILDE 108
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03216 109 PTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-216 |
2.20e-22 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 94.52 E-value: 2.20e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavvdykndDLA------ 74
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGV--------DLShvppyq 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 KKLSILKQTNHTEMNITVEQLVNFG----RFPyskgrmKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTI 150
Cdd:PRK11607 91 RPINMMFQSYALFPHMTVEQNIAFGlkqdKLP------KAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSL 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 151 AQDTDYILLDEPLNNLDMK----HSVQIMQTLRRlckdLNKTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:PRK11607 165 AKRPKLLLLDEPMGALDKKlrdrMQLEVVDILER----VGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQ 230
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
2-225 |
3.25e-22 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 95.16 E-value: 3.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILK 81
Cdd:PRK10789 316 VNIRQFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVS 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTeMNITVEQLVNFGRFPYSKgrmkkedyEQVEYAL-------DLLQL-----QSIRHRNIkTLSGGQRQRAYIAMT 149
Cdd:PRK10789 396 QTPFL-FSDTVANNIALGRPDATQ--------QEIEHVArlasvhdDILRLpqgydTEVGERGV-MLSGGQKQRISIARA 465
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINfASCYSDDIIALKNGEIVKADTKDNVIQ 225
Cdd:PRK10789 466 LLLNAEILILDDALSAVDGRTEHQILHNLRQWGE--GRTVIISAHRLS-ALTEASEILVMQHGHIAQRGNHDQLAQ 538
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
12-215 |
3.91e-22 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 90.06 E-value: 3.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKnDDLAKKLSILKQTNHTeMNIT 91
Cdd:cd03247 13 QEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLE-KALSSLISVLNQRPYL-FDTT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQlvNFGRfpyskgrmkkedyeqveyaldllqlqsirhrnikTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHS 171
Cdd:cd03247 91 LRN--NLGR----------------------------------RFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITE 134
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 807234162 172 VQIMQTLRRLCKDlnKTIVIVLHDINFAScYSDDIIALKNGEIV 215
Cdd:cd03247 135 RQLLSLIFEVLKD--KTLIWITHHLTGIE-HMDKILFLENGKII 175
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-221 |
4.16e-22 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 91.76 E-value: 4.16e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE-----KGTIKIEGKAVVDYKND--DL 73
Cdd:PRK14239 5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNpevtiTGSIVYNGHNIYSPRTDtvDL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 74 AKKLS-ILKQTNHTEMNItVEQLVNFGRFpysKGRMKKEDY-EQVEYALDLL----QLQSIRHRNIKTLSGGQRQRAYIA 147
Cdd:PRK14239 85 RKEIGmVFQQPNPFPMSI-YENVVYGLRL---KGIKDKQVLdEAVEKSLKGAsiwdEVKDRLHDSALGLSGGQQQRVCIA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 148 MTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSDDIIALKNGEIVK-ADTKD 221
Cdd:PRK14239 161 RVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDRTGFFLDGDLIEyNDTKQ 233
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
12-195 |
4.17e-22 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 94.73 E-value: 4.17e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTeMNIT 91
Cdd:TIGR02868 346 GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVCAQDAHL-FDTT 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVNFGRfpyskgrmKKEDYEQVEYAL------DLLQ-----LQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:TIGR02868 425 VRENLRLAR--------PDATDEELWAALervglaDWLRalpdgLDTVLGEGGARLSGGERQRLALARALLADAPILLLD 496
|
170 180 190
....*....|....*....|....*....|....*
gi 807234162 161 EPLNNLDMKHSVQIMQTLrrLCKDLNKTIVIVLHD 195
Cdd:TIGR02868 497 EPTEHLDAETADELLEDL--LAALSGRTVVLITHH 529
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-215 |
4.18e-22 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 94.75 E-value: 4.18e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIeGKAV----VDYKNDDLAKK 76
Cdd:COG0488 315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETVkigyFDQHQEELDPD 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSI---LKQTNHTEMNITVEQLVnfGRFPYSKGRMKKEdyeqveyaldllqlqsirhrnIKTLSGGQRQRAYIAMTIAQD 153
Cdd:COG0488 394 KTVldeLRDGAPGGTEQEVRGYL--GRFLFSGDDAFKP---------------------VGVLSGGEKARLALAKLLLSP 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 154 TDYILLDEPLNNLDmkhsvqiMQTLRRLCKDLNK---TIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:COG0488 451 PNVLLLDEPTNHLD-------IETLEALEEALDDfpgTVLLVSHDRYFLDRVATRILEFEDGGVR 508
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-221 |
4.48e-22 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 92.81 E-value: 4.48e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFE---YEKGTIKIEGKAVVDYKNDDL 73
Cdd:COG0444 1 LLEVRNLKVYFPTRrgvvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLKLSEKEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 74 ----AKKLSILKQTNHTEMN--ITV-----EQLVNFGRFPyskgrmKKEDYEQVEYALDLLQLQSIRHRnIK----TLSG 138
Cdd:COG0444 81 rkirGREIQMIFQDPMTSLNpvMTVgdqiaEPLRIHGGLS------KAEARERAIELLERVGLPDPERR-LDryphELSG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 139 GQRQRAYIAMTIAQDTDYILLDEPLNNLDMkhSVQ--IMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV- 215
Cdd:COG0444 154 GMRQRVMIARALALEPKLLIADEPTTALDV--TIQaqILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVe 231
|
....*.
gi 807234162 216 KADTKD 221
Cdd:COG0444 232 EGPVEE 237
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
17-216 |
4.82e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 92.08 E-value: 4.82e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTE-MNITVEQL 95
Cdd:PRK13642 23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKIGMVFQNPDNQfVGATVEDD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 96 VNFGRfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIM 175
Cdd:PRK13642 103 VAFGM--ENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIM 180
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 807234162 176 QTLRRLCKDLNKTIVIVLHDINFASCySDDIIALKNGEIVK 216
Cdd:PRK13642 181 RVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIK 220
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-245 |
4.96e-22 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 91.69 E-value: 4.96e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKA-----IQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK 75
Cdd:COG1101 1 MLELKNLSKTfnpgtVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 KLSILKQ--TNHTEMNITVEQlvNF-------GRFPYSKGrMKKEDYEQVEYALDLLQLqSIRHR---NIKTLSGGQRQR 143
Cdd:COG1101 81 YIGRVFQdpMMGTAPSMTIEE--NLalayrrgKRRGLRRG-LTKKRRELFRELLATLGL-GLENRldtKVGLLSGGQRQA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 144 AYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV---KADTK 220
Cdd:COG1101 157 LSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRIIldvSGEEK 236
|
250 260
....*....|....*....|....*
gi 807234162 221 DNVIQAEILKQLyemdvhiEEIRGQ 245
Cdd:COG1101 237 KKLTVEDLLELF-------EEIRGE 254
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
16-215 |
9.54e-22 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 94.02 E-value: 9.54e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK----KLSILKQTNHTEMNIT 91
Cdd:PRK10535 23 VLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQlrreHFGFIFQRYHLLSHLT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVnfgRFP--YSkGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMK 169
Cdd:PRK10535 103 AAQNV---EVPavYA-GLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSH 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 807234162 170 HSVQIMQTLRRLCkDLNKTIVIVLHDINFAScYSDDIIALKNGEIV 215
Cdd:PRK10535 179 SGEEVMAILHQLR-DRGHTVIIVTHDPQVAA-QAERVIEIRDGEIV 222
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
17-215 |
1.46e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 91.22 E-value: 1.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKG-TIKIEGKAVVDYKN----DDLAKKLSILKQTNHTEM-NI 90
Cdd:PRK13645 27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGqTIVGDYAIPANLKKikevKRLRKEIGLVFQFPEYQLfQE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 TVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQL-QSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMK 169
Cdd:PRK13645 107 TIEKDIAFG--PVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPK 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 807234162 170 HSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK13645 185 GEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVI 230
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
2-215 |
1.48e-21 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 90.07 E-value: 1.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvDYKND-------DLA 74
Cdd:COG4161 3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQF-DFSQKpsekairLLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 KKLSILKQTNHTEMNITVEQlvNFGRFPYS-KGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:COG4161 82 QKVGMVFQQYNLWPHLTVME--NLIEAPCKvLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMME 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:COG4161 160 PQVLLFDEPTAALDPEITAQVVEIIREL-SQTGITQVIVTHEVEFARKVASQVVYMEKGRII 220
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
14-232 |
2.02e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 90.63 E-value: 2.02e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLF---EYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTE-MN 89
Cdd:PRK13640 20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpdDNPNSKITVDGITLTAKTVWDIREKVGIVFQNPDNQfVG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 90 ITVEQLVNFG--RFPYSKGRMKKeDYEQVEYALDLLQLQSIRHRNiktLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLD 167
Cdd:PRK13640 100 ATVGDDVAFGleNRAVPRPEMIK-IVRDVLADVGMLDYIDSEPAN---LSGGQKQRVAIAGILAVEPKIIILDESTSMLD 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 168 MKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVI-QAEILKQL 232
Cdd:PRK13640 176 PAGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKLLAQGSPVEIFsKVEMLKEI 240
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1-237 |
2.54e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 90.56 E-value: 2.54e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQ-NKPI----LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIeGKAVVDYKNDD--- 72
Cdd:PRK13643 1 MIKFEKVNYTYQpNSPFasraLFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTV-GDIVVSSTSKQkei 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 --LAKKLSILKQTNHTEM-NITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQL-QSIRHRNIKTLSGGQRQRAYIAM 148
Cdd:PRK13643 80 kpVRKKVGVVFQFPESQLfEETVLKDVAFG--PQNFGIPKEKAEKIAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 149 TIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEI 228
Cdd:PRK13643 158 ILAMEPEVLVLDEPTAGLDPKARIEMMQLFESI-HQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQEVD 236
|
....*....
gi 807234162 229 LKQLYEMDV 237
Cdd:PRK13643 237 FLKAHELGV 245
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
2-221 |
2.70e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 90.53 E-value: 2.70e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNK-PI----LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKK 76
Cdd:PRK13651 3 IKVKNIVKIFNKKlPTelkaLDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSI-----------LKQTNHTEMNI--------------TVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQL-QSIRH 130
Cdd:PRK13651 83 VLEklviqktrfkkIKKIKEIRRRVgvvfqfaeyqlfeqTIEKDIIFG--PVSMGVSKEEAKKRAAKYIELVGLdESYLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 131 RNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALK 210
Cdd:PRK13651 161 RSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTKRTIFFK 239
|
250
....*....|..
gi 807234162 211 NGEIVK-ADTKD 221
Cdd:PRK13651 240 DGKIIKdGDTYD 251
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-233 |
6.13e-21 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 88.40 E-value: 6.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKK-LSI 79
Cdd:PRK11614 5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREaVAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTEMNITVEQLVNFGRFpyskgRMKKEDYEQ-VEYALDLL-QLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYI 157
Cdd:PRK11614 85 VPEGRRVFSRMTVEENLAMGGF-----FAERDQFQErIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 158 LLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLY 233
Cdd:PRK11614 160 LLDEPSLGLAPIIIQQIFDTIEQL-REQGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEAVRSAY 234
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-216 |
8.96e-21 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 88.36 E-value: 8.96e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE-----KGTIKIEGKAVVDYKND--DLA 74
Cdd:PRK14267 5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNIYSPDVDpiEVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 KKLSILKQTNHTEMNITVEQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQL-QSIRHR---NIKTLSGGQRQRAYIAMTI 150
Cdd:PRK14267 85 REVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKSKKELDERVEWALKKAALwDEVKDRlndYPSNLSGGQRQRLVIARAL 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:PRK14267 165 AMKPKILLMDEPTANIDPVGTAKIEELLFELKKEY--TIVLVTHSPAQAARVSDYVAFLYLGKLIE 228
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-231 |
1.00e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 88.71 E-value: 1.00e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQ-NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:PRK13652 3 LIETRDLCYSYSgSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTEM-NITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:PRK13652 83 VFQNPDDQIfSPTVEQDIAFG--PINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV-IQAEILKQ 231
Cdd:PRK13652 161 LDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIfLQPDLLAR 234
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
7-216 |
1.20e-20 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 87.94 E-value: 1.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 7 LDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdYKNDDLAKK-----LSILK 81
Cdd:TIGR02769 17 LFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDL--YQLDRKQRRafrrdVQLVF 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMN--ITVEQLVnfgRFPYSK-GRMKKEdyEQVEYALDLLQLQSIR----HRNIKTLSGGQRQRAYIAMTIAQDT 154
Cdd:TIGR02769 95 QDSPSAVNprMTVRQII---GEPLRHlTSLDES--EQKARIAELLDMVGLRsedaDKLPRQLSGGQLQRINIARALAVKP 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 155 DYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:TIGR02769 170 KLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVE 231
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-195 |
1.21e-20 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 90.51 E-value: 1.21e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 4 IKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKI----------------EGKAVVD 67
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIpkglrigylpqeppldDDLTVLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 68 YKNDDLAKKLSILKQTNHTE--MNITVEQLVNFGRFpysKGRMKKED-YE---QVEYALDLLQL-QSIRHRNIKTLSGGQ 140
Cdd:COG0488 81 TVLDGDAELRALEAELEELEakLAEPDEDLERLAEL---QEEFEALGgWEaeaRAEEILSGLGFpEEDLDRPVSELSGGW 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 141 RQRAYIAMTIAQDTDYILLDEPLNNLDMkHSVqimQTLRRLCKDLNKTIVIVLHD 195
Cdd:COG0488 158 RRRVALARALLSEPDLLLLDEPTNHLDL-ESI---EWLEEFLKNYPGTVLVVSHD 208
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
17-233 |
1.48e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 88.35 E-value: 1.48e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAV---VDYKN-DDLAKKLSILKQTNHTEM-NIT 91
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpeTGNKNlKKLRKKVSLVFQFPEAQLfENT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQL-QSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKH 170
Cdd:PRK13641 103 VLKDVEFG--PKNFGFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEG 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 171 SVQIMQtlrrLCKDLNK---TIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQ-AEILKQLY 233
Cdd:PRK13641 181 RKEMMQ----LFKDYQKaghTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSdKEWLKKHY 243
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
2-226 |
1.70e-20 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 90.31 E-value: 1.70e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQN--KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:TIGR03375 464 IEFRNVSFAYPGqeTPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRRNIGY 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQtNHTEMNITVEQLVNFGRfPYSkgrmkkEDYEQVEyALDL-------------LQLQsIRHRNiKTLSGGQRQRAYI 146
Cdd:TIGR03375 544 VPQ-DPRLFYGTLRDNIALGA-PYA------DDEEILR-AAELagvtefvrrhpdgLDMQ-IGERG-RSLSGGQRQAVAL 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 147 AMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQA 226
Cdd:TIGR03375 613 ARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRWLAG--KTLVLVTHRTSLLD-LVDRIIVMDNGRIVADGPKDQVLEA 689
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
2-232 |
1.71e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 88.18 E-value: 1.71e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNL-----DKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVD--YKNDDLA 74
Cdd:PRK13637 3 IKIENLthiymEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDkkVKLSDIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 KKLSILKQ-TNHTEMNITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQL--QSIRHRNIKTLSGGQRQRAYIAMTIA 151
Cdd:PRK13637 83 KKVGLVFQyPEYQLFEETIEKDIAFG--PINLGLSEEEIENRVKRAMNIVGLdyEDYKDKSPFELSGGQKRRVAIAGVVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 152 QDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI-QAEILK 230
Cdd:PRK13637 161 MEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFkEVETLE 240
|
..
gi 807234162 231 QL 232
Cdd:PRK13637 241 SI 242
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
12-209 |
2.34e-20 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 86.62 E-value: 2.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGkaVVDYKN-DDLAKKLS-ILKQTNHTEMN 89
Cdd:cd03267 32 REVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG--LVPWKRrKKFLRRIGvVFGQKTQLWWD 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 90 ITVEQLVNFGRFPYskgRMKKEDY-EQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDM 168
Cdd:cd03267 110 LPVIDSFYLLAAIY---DLPPARFkKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDV 186
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 807234162 169 KHSVQIMQTLRRLCKDLNKTIVIVLHDInfascysDDIIAL 209
Cdd:cd03267 187 VAQENIRNFLKEYNRERGTTVLLTSHYM-------KDIEAL 220
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1-215 |
3.91e-20 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 86.17 E-value: 3.91e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPIlkNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavvDYKNDDLAKK-LSI 79
Cdd:PRK10771 1 MLKLTDITWLYHHLPM--RFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQ---DHTTTPPSRRpVSM 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTEMNITVEQLVNFGRFPyskG-RMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:PRK10771 76 LFQENNLFSHLTVAQNIGLGLNP---GlKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK10771 153 LDEPFSALDPALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIA 209
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
2-218 |
4.16e-20 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 85.72 E-value: 4.16e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPI--LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGkavVDYKN---DDLAKK 76
Cdd:cd03245 3 IEFRNVSFSYPNQEIpaLDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDG---TDIRQldpADLRRN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTeMNITVEQLVNFGRfPYSkgrmkkeDYEQVEYALDL-------------LQLQsIRHRNiKTLSGGQRQR 143
Cdd:cd03245 80 IGYVPQDVTL-FYGTLRDNITLGA-PLA-------DDERILRAAELagvtdfvnkhpngLDLQ-IGERG-RGLSGGQRQA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 144 AYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIVLHDINFAScYSDDIIALKNGEIVkAD 218
Cdd:cd03245 149 VALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGD--KTLIIITHRPSLLD-LVDRIIVMDSGRIV-AD 219
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
2-225 |
4.32e-20 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 86.22 E-value: 4.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDDLAKKLSILK 81
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNH-FDFSKTPSDKAIRELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 -------QTNHTEMNITVEQlvNFGRFPYS-KGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:PRK11124 82 rnvgmvfQQYNLWPHLTVQQ--NLIEAPCRvLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMME 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQ 225
Cdd:PRK11124 160 PQVLLFDEPTAALDPEITAQIVSIIREL-AETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASCFTQ 230
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
23-207 |
4.37e-20 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 86.31 E-value: 4.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 23 DIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvDYKnddlakklsilKQTNHTEMNITVEQLVnfgrfp 102
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTV-SYK-----------PQYIKADYEGTVRDLL------ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 103 YSKGRMKKED-YEQVEYAlDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRL 181
Cdd:cd03237 83 SSITKDFYTHpYFKTEIA-KPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRF 161
|
170 180
....*....|....*....|....*.
gi 807234162 182 CKDLNKTIVIVLHDINFASCYSDDII 207
Cdd:cd03237 162 AENNEKTAFVVEHDIIMIDYLADRLI 187
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
16-235 |
5.31e-20 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 85.62 E-value: 5.31e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNhTEMNITVEQL 95
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVVLQEN-VLFNRSIRDN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 96 VNFGRfpyskgrmKKEDYEQVEYALDL-------LQL----QSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLN 164
Cdd:cd03252 96 IALAD--------PGMSMERVIEAAKLagahdfiSELpegyDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATS 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 165 NLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFASCySDDIIALKNGEIVKADTKDNVIQAEIL-KQLYEM 235
Cdd:cd03252 168 ALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAENGLyAYLYQL 236
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-204 |
7.84e-20 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 85.86 E-value: 7.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEkGTIKIEGKavVDYKNDDL-AKKLSIL 80
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELE-SEVRVEGR--VEFFNQNIyERRVNLN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLvnfgrFPYS------------KGRMKKEDYEQVEYALDLLQL-QSIRHRNIKT---LSGGQRQRA 144
Cdd:PRK14258 85 RLRRQVSMVHPKPNL-----FPMSvydnvaygvkivGWRPKLEIDDIVESALKDADLwDEIKHKIHKSaldLSGGQQQRL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSD 204
Cdd:PRK14258 160 CIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSD 219
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
10-226 |
1.21e-19 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 87.79 E-value: 1.21e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 10 AIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQtnHTE-M 88
Cdd:TIGR01842 327 PGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKHIGYLPQ--DVElF 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 89 NITVEQlvNFGRFPyskgrmKKEDYEQVEYALDLLQLqsirHRNI---------------KTLSGGQRQRAYIAMTIAQD 153
Cdd:TIGR01842 405 PGTVAE--NIARFG------ENADPEKIIEAAKLAGV----HELIlrlpdgydtvigpggATLSGGQRQRIALARALYGD 472
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCySDDIIALKNGEIVKADTKDNVIQA 226
Cdd:TIGR01842 473 PKLVVLDEPNSNLDEEGEQALANAIKAL-KARGITVVVITHRPSLLGC-VDKILVLQDGRIARFGERDEVLAK 543
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-215 |
1.26e-19 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 87.38 E-value: 1.26e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDDLAKKLSIl 80
Cdd:COG1129 4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEP-VRFRSPRDAQAAGI- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 kQTNHTEMNI----TVEQLVNFGRFPYSKGRM-KKEDYEQVEYALDLLQLqSIR-HRNIKTLSGGQRQRAYIAMTIAQDT 154
Cdd:COG1129 82 -AIIHQELNLvpnlSVAENIFLGREPRRGGLIdWRAMRRRARELLARLGL-DIDpDTPVGDLSVAQQQLVEIARALSRDA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 155 DYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDIN--FASCysDDIIALKNGEIV 215
Cdd:COG1129 160 RVLILDEPTASLTEREVERLFRIIRRL-KAQGVAIIYISHRLDevFEIA--DRVTVLRDGRLV 219
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-215 |
1.60e-19 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 86.29 E-value: 1.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKK 76
Cdd:COG1135 1 MIELENLSKTFPTKggpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 -------------LSilkqtnhtemNITVEQLVnfgRFP-----YSKGRMKKedyeQVEYALDLLQLQSIRHRNIKTLSG 138
Cdd:COG1135 81 rrkigmifqhfnlLS----------SRTVAENV---ALPleiagVPKAEIRK----RVAELLELVGLSDKADAYPSQLSG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 139 GQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHD------InfasCysDDIIALKNG 212
Cdd:COG1135 144 GQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEmdvvrrI----C--DRVAVLENG 217
|
...
gi 807234162 213 EIV 215
Cdd:COG1135 218 RIV 220
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
14-215 |
2.13e-19 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 83.74 E-value: 2.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdyknddlakklSILKQTNHTEMNITVE 93
Cdd:cd03220 35 FWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVS------------SLLGLGGGFNPELTGR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 94 QLVNF-GRFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSV 172
Cdd:cd03220 103 ENIYLnGRL---LGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQE 179
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 807234162 173 QIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:cd03220 180 KCQRRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIR 221
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
2-214 |
3.72e-19 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 81.88 E-value: 3.72e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAI--QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:cd03246 1 LEVENVSFRYpgAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTnhtemnitveqlvnfgrfpyskgrmkkedyeqveyalDLLQLQSIRHrNIktLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:cd03246 81 LPQD-------------------------------------DELFSGSIAE-NI--LSGGQRQRLGLARALYGNPRILVL 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDIN-FASCysDDIIALKNGEI 214
Cdd:cd03246 121 DEPNSHLDVEGERALNQAIAAL-KAAGATRIVIAHRPEtLASA--DRILVLEDGRV 173
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-223 |
4.56e-19 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 83.62 E-value: 4.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYknddLAKKLSIl 80
Cdd:PRK09544 4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGY----VPQKLYL- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 kqtnHTEMNITVEqlvnfgRFPYSKGRMKKEDyeqVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:PRK09544 79 ----DTTLPLTVN------RFLRLRPGTKKED---ILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLD 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALkNGEIVKADTKDNV 223
Cdd:PRK09544 146 EPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCL-NHHICCSGTPEVV 207
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
1-178 |
4.87e-19 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 82.61 E-value: 4.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavvDYKNDDLAKKLSIL 80
Cdd:PRK13539 2 MLEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGG---DIDDPDVAEACHYL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVNFGRfpyskgRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:PRK13539 79 GHRNAMKPALTVAENLEFWA------AFLGGEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILD 152
|
170
....*....|....*...
gi 807234162 161 EPLNNLDmKHSVQIMQTL 178
Cdd:PRK13539 153 EPTAALD-AAAVALFAEL 169
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1-219 |
7.25e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 83.26 E-value: 7.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKP--ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLS 78
Cdd:PRK13648 7 IIVFKNVSFQYQSDAsfTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKHIG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTE-MNITVEQLVNFG----RFPYskgrmkKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:PRK13648 87 IVFQNPDNQfVGSIVKYDVAFGlenhAVPY------DEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALN 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEIVKADT 219
Cdd:PRK13648 161 PSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAM-EADHVIVMNKGTVYKEGT 225
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
15-225 |
7.88e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 83.26 E-value: 7.88e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVV-DYKNDDLA---KKLSILKQTNHTEM-N 89
Cdd:PRK13649 21 RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITsTSKNKDIKqirKKVGLVFQFPESQLfE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 90 ITVEQLVNFGrfPYSKGrMKKEDYEQVeyALDLLQL----QSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNN 165
Cdd:PRK13649 101 ETVLKDVAFG--PQNFG-VSQEEAEAL--AREKLALvgisESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAG 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 166 LDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQ 225
Cdd:PRK13649 176 LDPKGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQ 234
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-251 |
9.69e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 85.24 E-value: 9.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEK---------------GTIKIEGKA-- 64
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYEPtsgriiyhvalcekcGYVERPSKVge 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 65 ------------VVDYKNDD------LAKKLSILKQT------NHTEMNITVEQLVNFGRfpyskgrmkkEDYEQVEYAL 120
Cdd:TIGR03269 81 pcpvcggtlepeEVDFWNLSdklrrrIRKRIAIMLQRtfalygDDTVLDNVLEALEEIGY----------EGKEAVGRAV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 121 DLLQLQSIRHRNI---KTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDIN 197
Cdd:TIGR03269 151 DLIEMVQLSHRIThiaRDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPE 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 198 FASCYSDDIIALKNGEIVKADTKDNVI-----QAEILKQLYEMDVHIEEIRGQRICLYY 251
Cdd:TIGR03269 231 VIEDLSDKAIWLENGEIKEEGTPDEVVavfmeGVSEVEKECEVEVGEPIIKVRNVSKRY 289
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-215 |
1.29e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 84.90 E-value: 1.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLD-KAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEkGTIKIEGkavVDYKNDDLA---KKL 77
Cdd:PRK11174 350 IEAEDLEiLSPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQ-GSLKING---IELRELDPEswrKHL 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILKQtNHTEMNITVEQLVNFGRFPYSKgrmkkedyEQVEYALDLLQLQS------------IRHRNIkTLSGGQRQRAY 145
Cdd:PRK11174 426 SWVGQ-NPQLPHGTLRDNVLLGNPDASD--------EQLQQALENAWVSEflpllpqgldtpIGDQAA-GLSVGQAQRLA 495
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 146 IAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIVLHDINFASCYsDDIIALKNGEIV 215
Cdd:PRK11174 496 LARALLQPCQLLLLDEPTASLDAHSEQLVMQALNAASRR--QTTLMVTHQLEDLAQW-DQIWVMQDGQIV 562
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
17-216 |
1.33e-18 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 84.58 E-value: 1.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVdYKN--DDLAKKLSILKQTNHTEMNITVEQ 94
Cdd:PRK11288 20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMR-FASttAALAAGVAIIYQELHLVPEMTVAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGRFPYSKGRMKKED-YEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQ 173
Cdd:PRK11288 99 NLYLGQLPHKGGIVNRRLlNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQ 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 807234162 174 IMQTLRRLcKDLNKTIVIVLH--DINFASCysDDIIALKNGEIVK 216
Cdd:PRK11288 179 LFRVIREL-RAEGRVILYVSHrmEEIFALC--DAITVFKDGRYVA 220
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-215 |
1.79e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 84.49 E-value: 1.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAI--QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:PRK11160 339 LTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQAISV 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQT----NHT--------EMNITVEQLVnfgrfpyskgrmkkEDYEQVEyaLDLLqLQSIRHRNI------KTLSGGQR 141
Cdd:PRK11160 419 VSQRvhlfSATlrdnlllaAPNASDEALI--------------EVLQQVG--LEKL-LEDDKGLNAwlgeggRQLSGGEQ 481
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 142 QRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIVLHDINfASCYSDDIIALKNGEIV 215
Cdd:PRK11160 482 RRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQN--KTVLMITHRLT-GLEQFDRICVMDNGQII 552
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
20-223 |
1.81e-18 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 83.24 E-value: 1.81e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 20 INVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDY-KNDDLA---KKLSILKQTNHTEMNITVEQL 95
Cdd:TIGR02142 16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSrKGIFLPpekRRIGYVFQEARLFPHLSVRGN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 96 VNFGRfpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIM 175
Cdd:TIGR02142 96 LRYGM----KRARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEIL 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 807234162 176 QTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV 223
Cdd:TIGR02142 172 PYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEV 219
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-235 |
1.87e-18 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 83.34 E-value: 1.87e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNddLAK-KLSIL 80
Cdd:PRK13536 42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARAR--LARaRIGVV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITV-EQLVNFGRFpyskGRMKKEDYEQV-EYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:PRK13536 120 PQFDNLDLEFTVrENLLVFGRY----FGMSTREIEAViPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLI 195
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKdLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEM 235
Cdd:PRK13536 196 LDEPTTGLDPHARHLIWERLRSLLA-RGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALIDEHIGCQVIEI 271
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
17-198 |
2.27e-18 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 81.70 E-value: 2.27e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAvsrlfeyekgtikIEGKAVVD-----YKNDDLakklsilkqTNHTEMNI- 90
Cdd:COG4674 26 LNDLSLYVDPGELRVIIGPNGAGKTTLMDV-------------ITGKTRPDsgsvlFGGTDL---------TGLDEHEIa 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 -----------TV-EQL---------VNFGRFPYS--KGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIA 147
Cdd:COG4674 84 rlgigrkfqkpTVfEELtvfenlelaLKGDRGVFAslFARLTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIG 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 148 MTIAQDTDYILLDEPLNNldMKHSvQIMQT---LRRLCKDlnKTIVIVLHDINF 198
Cdd:COG4674 164 MLLAQDPKLLLLDEPVAG--MTDA-ETERTaelLKSLAGK--HSVVVVEHDMEF 212
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
12-226 |
3.89e-18 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 83.26 E-value: 3.89e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQtnHTE-MNI 90
Cdd:COG4618 343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRHIGYLPQ--DVElFDG 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 TVEQlvNFGRFPyskgrmkKEDYEQVEYALDLLQLqsirHRNI---------------KTLSGGQRQRAYIAMTIAQDTD 155
Cdd:COG4618 421 TIAE--NIARFG-------DADPEKVVAAAKLAGV----HEMIlrlpdgydtrigeggARLSGGQRQRIGLARALYGDPR 487
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 807234162 156 YILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCySDDIIALKNGEIVKADTKDNVIQA 226
Cdd:COG4618 488 LVVLDEPNSNLDDEGEAALAAAIRAL-KARGATVVVITHRPSLLAA-VDKLLVLRDGRVQAFGPRDEVLAR 556
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
17-224 |
4.59e-18 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 82.77 E-value: 4.59e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLA----KKLSILKQTNHTEMNITV 92
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRevrrKKIAMVFQSFALMPHMTV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNFGRfpYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSV 172
Cdd:PRK10070 124 LDNTAFGM--ELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRT 201
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 807234162 173 QIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:PRK10070 202 EMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
2-214 |
7.00e-18 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 80.40 E-value: 7.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILK 81
Cdd:PRK10619 6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKVADKN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNIT-VEQLVNFGRF----------PYSK-GRMKKEDYEQVEYALDLLQL-QSIRHRNIKTLSGGQRQRAYIAM 148
Cdd:PRK10619 86 QLRLLRTRLTmVFQHFNLWSHmtvlenvmeaPIQVlGLSKQEARERAVKYLAKVGIdERAQGKYPVHLSGGQQQRVSIAR 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 149 TIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:PRK10619 166 ALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEE-GKTMVVVTHEMGFARHVSSHVIFLHQGKI 230
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
13-226 |
7.95e-18 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 82.48 E-value: 7.95e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTEMNITV 92
Cdd:TIGR01193 486 GSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQFINYLPQEPYIFSGSIL 565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVnFGRFPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIK----TLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDM 168
Cdd:TIGR01193 566 ENLL-LGAKENVSQDEIWAACEIAEIKDDIENMPLGYQTELSeegsSISGGQKQRIALARALLTDSKVLILDESTSNLDT 644
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 169 KHSVQIMQTLRRLckdLNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQA 226
Cdd:TIGR01193 645 ITEKKIVNNLLNL---QDKTIIFVAHRLSVAK-QSDKIIVLDHGKIIEQGSHDELLDR 698
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
2-235 |
8.46e-18 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 79.89 E-value: 8.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKP---ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLS 78
Cdd:cd03249 1 IEFKNVSFRYPSRPdvpILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTeMNITVEQLVNFGRFPYSKgrmkkedyEQVEYALDLLQLqsirHRNI---------------KTLSGGQRQR 143
Cdd:cd03249 81 LVSQEPVL-FDGTIAENIRYGKPDATD--------EEVEEAAKKANI----HDFImslpdgydtlvgergSQLSGGQKQR 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 144 AYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNV 223
Cdd:cd03249 148 IAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRLSTIR-NADLIAVLQNGQVVEQGTHDEL 224
|
250
....*....|...
gi 807234162 224 IQAE-ILKQLYEM 235
Cdd:cd03249 225 MAQKgVYAKLVKA 237
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
19-215 |
8.65e-18 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 81.30 E-value: 8.65e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 19 NINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDyknddlakklsilkqtnhTEMNI-------- 90
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQD------------------SARGIflpphrrr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 --------------TVEQLVNFGRfpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDY 156
Cdd:COG4148 79 igyvfqearlfphlSVRGNLLYGR----KRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 157 ILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:COG4148 155 LLMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVV 213
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-162 |
1.07e-17 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 79.30 E-value: 1.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVD---YKNddlAKK- 76
Cdd:COG1137 3 TLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHlpmHKR---ARLg 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQtnhtEMNI----TVEQ-------LVNFGrfpyskgrmKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAY 145
Cdd:COG1137 80 IGYLPQ----EASIfrklTVEDnilavleLRKLS---------KKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVE 146
|
170
....*....|....*..
gi 807234162 146 IAMTIAQDTDYILLDEP 162
Cdd:COG1137 147 IARALATNPKFILLDEP 163
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
2-214 |
1.78e-17 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 78.67 E-value: 1.78e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKP---ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLS 78
Cdd:cd03248 12 VKFQNVTFAYPTRPdtlVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHSKVS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQtNHTEMNITVEQLVNFGRFPYSKGRMKKEdyEQVEYALDLLQLQSirhRNIKT--------LSGGQRQRAYIAMTI 150
Cdd:cd03248 92 LVGQ-EPVLFARSLQDNIAYGLQSCSFECVKEA--AQKAHAHSFISELA---SGYDTevgekgsqLSGGQKQRVAIARAL 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRrlCKDLNKTIVIVLHDINFAScYSDDIIALKNGEI 214
Cdd:cd03248 166 IRNPQVLILDEATSALDAESEQQVQQALY--DWPERRTVLVIAHRLSTVE-RADQILVLDGGRI 226
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
23-207 |
1.85e-17 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 81.37 E-value: 1.85e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 23 DIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGtiKIEGKAVVDYKnddlakklsilKQTNHTEMNITVEQL---VNFG 99
Cdd:COG1245 362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEG--EVDEDLKISYK-----------PQYISPDYDGTVEEFlrsANTD 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 100 RFPYSkgrmkkedYEQVEYAlDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLR 179
Cdd:COG1245 429 DFGSS--------YYKTEII-KPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIR 499
|
170 180
....*....|....*....|....*...
gi 807234162 180 RLCKDLNKTIVIVLHDINFASCYSDDII 207
Cdd:COG1245 500 RFAENRGKTAMVVDHDIYLIDYISDRLM 527
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-215 |
4.51e-17 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 80.21 E-value: 4.51e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDDLAKKL--S 78
Cdd:PRK09700 5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNIN-YNKLDHKLAAQLgiG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTEMNITVEQLVNFGRFPYSK---------GRMKkedyEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMT 149
Cdd:PRK09700 84 IIYQELSVIDELTVLENLYIGRHLTKKvcgvniidwREMR----VRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKT 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK09700 160 LMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDGSSV 224
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
14-194 |
5.14e-17 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 80.09 E-value: 5.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSrlFEYEKG-----TIKIEGKAVvdykNDDLAKKLSILKQTNhtEM 88
Cdd:TIGR00955 38 KHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALA--FRSPKGvkgsgSVLLNGMPI----DAKEMRAISAYVQQD--DL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 89 NI---TVEQLVNF------GRFPYSKGRMkkedyEQVEYALDLLQLQSIRHRNI------KTLSGGQRQRAYIAMTIAQD 153
Cdd:TIGR00955 110 FIptlTVREHLMFqahlrmPRRVTKKEKR-----ERVDEVLQALGLRKCANTRIgvpgrvKGLSGGERKRLAFASELLTD 184
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 807234162 154 TDYILLDEPLNNLD--MKHSVqiMQTLRRLCkDLNKTIVIVLH 194
Cdd:TIGR00955 185 PPLLFCDEPTSGLDsfMAYSV--VQVLKGLA-QKGKTIICTIH 224
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-194 |
6.24e-17 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 79.07 E-value: 6.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK- 75
Cdd:PRK11153 1 MIELKNISKVFPQGgrtiHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 --KLSILKQtnHteMNI----TVEQLVnfgRFPYSKGRMKKEDYEQ-VEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAM 148
Cdd:PRK11153 81 rrQIGMIFQ--H--FNLlssrTVFDNV---ALPLELAGTPKAEIKArVTELLELVGLSDKADRYPAQLSGGQKQRVAIAR 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 807234162 149 TIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLH 194
Cdd:PRK11153 154 ALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITH 199
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-226 |
7.53e-17 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 77.78 E-value: 7.53e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKaVVDYKND-------DL 73
Cdd:PRK14246 10 VFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGK-VLYFGKDifqidaiKL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 74 AKKLSILKQTNHTEMNITVEQlvNFGRFPYSKG-RMKKEDYEQVEYALDLLQLQSIRHRNIKT----LSGGQRQRAYIAM 148
Cdd:PRK14246 89 RKEVGMVFQQPNPFPHLSIYD--NIAYPLKSHGiKEKREIKKIVEECLRKVGLWKEVYDRLNSpasqLSGGQQQRLTIAR 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 149 TIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQA 226
Cdd:PRK14246 167 ALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEI--AIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTS 242
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
27-206 |
8.66e-17 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 77.41 E-value: 8.66e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 27 GRLTSLIGPNGAGKSTLLSAVSrlfeyekgtikieGKAVVDY-KNDDLAKKLSILKQTNHTEMNITVEQLVNFG------ 99
Cdd:cd03236 26 GQVLGLVGPNGIGKSTALKILA-------------GKLKPNLgKFDDPPDWDEILDEFRGSELQNYFTKLLEGDvkvivk 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 100 -----RFPYS-KGRM-----KKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDM 168
Cdd:cd03236 93 pqyvdLIPKAvKGKVgellkKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDI 172
|
170 180 190
....*....|....*....|....*....|....*...
gi 807234162 169 KHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDI 206
Cdd:cd03236 173 KQRLNAARLIRELAED-DNYVLVVEHDLAVLDYLSDYI 209
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
14-241 |
1.26e-16 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 79.40 E-value: 1.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAV-SRLFEYEKGTIKIEGKavVDYknddlAKKLSILkqtnhteMNITV 92
Cdd:PLN03130 630 RPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMlGELPPRSDASVVIRGT--VAY-----VPQVSWI-------FNATV 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNFGRfPYSKGRMKKE-DYEQVEYALDLL---QLQSIRHRNIkTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDM 168
Cdd:PLN03130 696 RDNILFGS-PFDPERYERAiDVTALQHDLDLLpggDLTEIGERGV-NISGGQKQRVSMARAVYSNSDVYIFDDPLSALDA 773
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 169 KHSVQIMQT-LRRLCKdlNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQ-AEILKQLYE----MDVHIEE 241
Cdd:PLN03130 774 HVGRQVFDKcIKDELR--GKTRVLVTNQLHFLS-QVDRIILVHEGMIKEEGTYEELSNnGPLFQKLMEnagkMEEYVEE 849
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
2-234 |
1.32e-16 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 75.64 E-value: 1.32e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE--KGTIKIEGKAVVDYKNDDLAKklsi 79
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEvtEGEILFKGEDITDLPPEERAR---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 lkqtnhteMNITVEqlvnfgrFPYSkgrmkkEDYEQVEYAlDLLqlqsirhRNI-KTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:cd03217 77 --------LGIFLA-------FQYP------PEIPGVKNA-DFL-------RYVnEGFSGGEKKRNEILQLLLLEPDLAI 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFAscysDDIIA-----LKNGEIVKADTKdnviqaEILKQLY 233
Cdd:cd03217 128 LDEPDSGLDIDALRLVAEVINKL-REEGKSVLIITHYQRLL----DYIKPdrvhvLYDGRIVKSGDK------ELALEIE 196
|
.
gi 807234162 234 E 234
Cdd:cd03217 197 K 197
|
|
| type_I_sec_HlyB |
TIGR01846 |
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ... |
15-227 |
1.59e-16 |
|
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273831 [Multi-domain] Cd Length: 694 Bit Score: 78.63 E-value: 1.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNhtemnitveq 94
Cdd:TIGR01846 471 EVLSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGVDLAIADPAWLRRQMGVVLQEN---------- 540
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 lVNFGRFPYSKGRMKKE--DYEQVEYALDL---LQLQSIRHRNIKT--------LSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:TIGR01846 541 -VLFSRSIRDNIALCNPgaPFEHVIHAAKLagaHDFISELPQGYNTevgekganLSGGQRQRIAIARALVGNPRILIFDE 619
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINfASCYSDDIIALKNGEIVKADTKDNVIQAE 227
Cdd:TIGR01846 620 ATSALDYESEALIMRNMREICR--GRTVIIIAHRLS-TVRACDRIIVLEKGQIAESGRHEELLALQ 682
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
24-207 |
1.97e-16 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 78.31 E-value: 1.97e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 24 IQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavVDYKnddlakklsilKQTNHTEMNITVEQLVnfgrfpy 103
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELK--ISYK-----------PQYIKPDYDGTVEDLL------- 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 104 skgRMKKEDYEQVEYALDL---LQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRR 180
Cdd:PRK13409 422 ---RSITDDLGSSYYKSEIikpLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRR 498
|
170 180
....*....|....*....|....*..
gi 807234162 181 LCKDLNKTIVIVLHDINFASCYSDDII 207
Cdd:PRK13409 499 IAEEREATALVVDHDIYMIDYISDRLM 525
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-195 |
1.97e-16 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 78.44 E-value: 1.97e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIeGKAV----VDYKNDDLAKKL 77
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETVklayVDQSRDALDPNK 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILKQ----TNHTEM-NITVEQLVNFGRFPYSKGRMKKedyeqveyaldllqlqsirhrNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:TIGR03719 402 TVWEEisggLDIIKLgKREIPSRAYVGRFNFKGSDQQK---------------------KVGQLSGGERNRVHLAKTLKS 460
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 807234162 153 DTDYILLDEPLNNLDmkhsVQIMQTLRRLCKDLNKTIVIVLHD 195
Cdd:TIGR03719 461 GGNVLLLDEPTNDLD----VETLRALEEALLNFAGCAVVISHD 499
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
17-215 |
2.37e-16 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 78.19 E-value: 2.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEkGTIKIEGKAVVDYKNDDLA---KKLSILKQTNHTEMN--IT 91
Cdd:COG4172 302 VDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIPSE-GEIRFDGQDLDGLSRRALRplrRRMQVVFQDPFGSLSprMT 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQLQ-SIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMkh 170
Cdd:COG4172 381 VGQIIAEGLRVHGPGLSAAERRARVAEALEEVGLDpAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDV-- 458
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 807234162 171 SVQ--IMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:COG4172 459 SVQaqILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVV 505
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-228 |
2.77e-16 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 76.77 E-value: 2.77e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDyKNDDLAKKLSILK 81
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPS-RARHARQRVGVVP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITV-EQLVNFGR-FPYSKGRMKkedyEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:PRK13537 87 QFDNLDPDFTVrENLLVFGRyFGLSAAAAR----ALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEI 228
Cdd:PRK13537 163 DEPTTGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIESEI 230
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1-209 |
3.14e-16 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 75.14 E-value: 3.14e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:PRK10247 7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQVSYC 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNITVEQLVnfgrFPYskgRMKKEDYEQVEYALDLLQL---QSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYI 157
Cdd:PRK10247 87 AQTPTLFGDTVYDNLI----FPW---QIRNQQPDPAIFLDDLERFalpDTILTKNIAELSGGEKQRISLIRNLQFMPKVL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 807234162 158 LLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIAL 209
Cdd:PRK10247 160 LLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEIN-HADKVITL 210
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
1-214 |
3.77e-16 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 75.61 E-value: 3.77e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:COG4598 8 ALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPDRDGELVPADR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMNI-------------TVEQLVNFGrfP-YSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYI 146
Cdd:COG4598 88 RQLQRIRTRLgmvfqsfnlwshmTVLENVIEA--PvHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAI 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 807234162 147 AMTIAQDTDYILLDEPLNNLD---MKHSVQIMQTLrrlcKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:COG4598 166 ARALAMEPEVMLFDEPTSALDpelVGEVLKVMRDL----AEEGRTMLVVTHEMGFARDVSSHVVFLHQGRI 232
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
4-214 |
4.01e-16 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 77.75 E-value: 4.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 4 IKNLDKAIQ--NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDDLAKKLSILK 81
Cdd:TIGR01257 931 VKNLVKIFEpsGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKD-IETNLDAVRQSLGMCP 1009
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFgrFPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:TIGR01257 1010 QHNILFHHLTVAEHILF--YAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDE 1087
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:TIGR01257 1088 PTSGVDPYSRRSIWDLLLKYRS--GRTIIMSTHHMDEADLLGDRIAIISQGRL 1138
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1-226 |
4.08e-16 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 77.59 E-value: 4.08e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEG-------KAVVDYK 69
Cdd:PRK10261 12 VLAVENLNIAFMQEqqkiAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKmllrrrsRQVIELS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 70 NDDLAK-------KLSILKQTNHTEMN--ITV-EQLVNFGRFpySKGRMKKEDYEQVEYALDLLQL---QSIRHRNIKTL 136
Cdd:PRK10261 92 EQSAAQmrhvrgaDMAMIFQEPMTSLNpvFTVgEQIAESIRL--HQGASREEAMVEAKRMLDQVRIpeaQTILSRYPHQL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 137 SGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:PRK10261 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVE 249
|
250
....*....|
gi 807234162 217 ADTKDNVIQA 226
Cdd:PRK10261 250 TGSVEQIFHA 259
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
12-219 |
5.30e-16 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 76.04 E-value: 5.30e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPI--LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEG------------------KAVVDYKNd 71
Cdd:PRK13631 35 QENELvaLNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDiyigdkknnhelitnpysKKIKNFKE- 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 72 dLAKKLSILKQTNHTEM-NITVEQLVNFGrfPYSKGRMKKEDYEQVEYALDLLQLQ-SIRHRNIKTLSGGQRQRAYIAMT 149
Cdd:PRK13631 114 -LRRRVSMVFQFPEYQLfKDTIEKDIMFG--PVALGVKKSEAKKLAKFYLNKMGLDdSYLERSPFGLSGGQKRRVAIAGI 190
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHSVQIMQTLRRlCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADT 219
Cdd:PRK13631 191 LAIQPEILIFDEPTAGLDPKGEHEMMQLILD-AKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGT 259
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-219 |
6.47e-16 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 74.39 E-value: 6.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNK----PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAK- 75
Cdd:COG4181 8 IIELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARARl 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 ---KLSILKQTNHTEMNITVeqLVN-------FGRfpyskgrmkKEDYEQVEYALDLLQLQS-IRHRNiKTLSGGQRQRA 144
Cdd:COG4181 88 rarHVGFVFQSFQLLPTLTA--LENvmlplelAGR---------RDARARARALLERVGLGHrLDHYP-AQLSGGEQQRV 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAS-CysDDIIALKNGEIVKADT 219
Cdd:COG4181 156 ALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAArC--DRVLRLRAGRLVEDTA 229
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-204 |
7.68e-16 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 74.82 E-value: 7.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGtIKIEGKavVDYKNDDL-AKKLSIL 80
Cdd:PRK14243 11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLIPG-FRVEGK--VTFHGKNLyAPDVDPV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTNHTEMnitVEQLVNfgRFPyskgrmkKEDYEQVEYA---------LDLLQLQSIRH------------RNIKTLSGG 139
Cdd:PRK14243 88 EVRRRIGM---VFQKPN--PFP-------KSIYDNIAYGaringykgdMDELVERSLRQaalwdevkdklkQSGLSLSGG 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 140 QRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSD 204
Cdd:PRK14243 156 QQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAARVSD 218
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
3-232 |
9.90e-16 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 74.33 E-value: 9.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE--KGTIKIEGKAVVDYKNDDLAKK---L 77
Cdd:COG0396 2 EIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKYEvtSGSILLDGEDILELSPDERARAgifL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SilkqtnhteMNITVE----QLVNFGRFPYSKGRMKKED----YEQVEYALDLLQL-QSIRHRNI-KTLSGGQRQRAYIA 147
Cdd:COG0396 82 A---------FQYPVEipgvSVSNFLRTALNARRGEELSarefLKLLKEKMKELGLdEDFLDRYVnEGFSGGEKKRNEIL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 148 MTIAQDTDYILLDEPLNNLDmkhsVQIMQTLRRLCKDL---NKTIVIVLHdinfascYS--------DDIIALKNGEIVK 216
Cdd:COG0396 153 QMLLLEPKLAILDETDSGLD----IDALRIVAEGVNKLrspDRGILIITH-------YQrildyikpDFVHVLVDGRIVK 221
|
250
....*....|....*.
gi 807234162 217 ADTKdnviqaEILKQL 232
Cdd:COG0396 222 SGGK------ELALEL 231
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
13-234 |
1.34e-15 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 75.91 E-value: 1.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQtNHTEMNITV 92
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQVALVGQ-EPVLFSGSV 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNFGRFPYSKGRMKKEdyEQVEYALDLLQ-LQSIRHRNI----KTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLD 167
Cdd:TIGR00958 572 RENIAYGLTDTPDEEIMAA--AKAANAHDFIMeFPNGYDTEVgekgSQLSGGQKQRIAIARALVRKPRVLILDEATSALD 649
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 168 mkhsVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTkdnviqaeiLKQLYE 234
Cdd:TIGR00958 650 ----AECEQLLQESRSRASRTVLLIAHRLSTVE-RADQILVLKKGSVVEMGT---------HKQLME 702
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
2-219 |
2.67e-15 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 72.53 E-value: 2.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLD-KAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:cd03244 3 IEFKNVSlRYRPNlPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSRISI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTeMNITV-EQLVNFGRfpYSKGRMK--------KEDYEQVEYALDLLQLqsirhRNIKTLSGGQRQRAYIAMTI 150
Cdd:cd03244 83 IPQDPVL-FSGTIrSNLDPFGE--YSDEELWqalervglKEFVESLPGGLDTVVE-----EGGENLSVGQRQLLCLARAL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 151 AQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlnKTIVIVLHDINfASCYSDDIIALKNGEIVKADT 219
Cdd:cd03244 155 LRKSKILVLDEATASVDPETDALIQKTIREAFKD--CTVLTIAHRLD-TIIDSDRILVLDKGRVVEFDS 220
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-216 |
3.19e-15 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 73.14 E-value: 3.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE--KGTIKIEGKAVVDYKNDDLAKKLS 78
Cdd:CHL00131 7 ILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPAYKilEGDILFKGESILDLEPEERAHLGI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILKQTNHTEMN-ITVEQlvnFGRFPYSKGR--MKKEDYEQVEY------ALDLLQL-QSIRHRNI-KTLSGGQRQRAYIA 147
Cdd:CHL00131 87 FLAFQYPIEIPgVSNAD---FLRLAYNSKRkfQGLPELDPLEFleiineKLKLVGMdPSFLSRNVnEGFSGGEKKRNEIL 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 148 MTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDII-ALKNGEIVK 216
Cdd:CHL00131 164 QMALLDSELAILDETDSGLDIDALKIIAEGINKL-MTSENSIILITHYQRLLDYIKPDYVhVMQNGKIIK 232
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1-196 |
3.26e-15 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 73.26 E-value: 3.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDL---AKKL 77
Cdd:PRK11831 7 LVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLytvRKRM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILKQTNHTEMNITVEQLVNF-----GRFPyskgrmkkedyEQVEYALDLLQLQSIRHRNIKT-----LSGGQRQRAYIA 147
Cdd:PRK11831 87 SMLFQSGALFTDMNVFDNVAYplrehTQLP-----------APLLHSTVMMKLEAVGLRGAAKlmpseLSGGMARRAALA 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 807234162 148 MTIAQDTDYILLDEPLNNLDmkhsVQIMQTLRRLCKDLNK----TIVIVLHDI 196
Cdd:PRK11831 156 RAIALEPDLIMFDEPFVGQD----PITMGVLVKLISELNSalgvTCVVVSHDV 204
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
2-215 |
3.77e-15 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 74.54 E-value: 3.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDY----KNDDLAKKL 77
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENANIGYyaqdHAYDFENDL 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SIL------KQTNHTEmnitveQLVN--FGRFPYSKGRMKKedyeqveyaldllqlqsirhrNIKTLSGGQRQRAYIAMT 149
Cdd:PRK15064 400 TLFdwmsqwRQEGDDE------QAVRgtLGRLLFSQDDIKK---------------------SVKVLSGGEKGRMLFGKL 452
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 150 IAQDTDYILLDEPLNNLDMKHsvqiMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK15064 453 MMQKPNVLVMDEPTNHMDMES----IESLNMALEKYEGTLIFVSHDREFVSSLATRIIEITPDGVV 514
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
2-219 |
4.94e-15 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 71.67 E-value: 4.94e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDK--AIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:cd03369 7 IEVENLSVryAPDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTEMNITVEQLVNFGRFpyskgrmkkeDYEQVEYALDLLQLQSirhrnikTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:cd03369 87 IPQDPTLFSGTIRSNLDPFDEY----------SDEEIYGALRVSEGGL-------NLSQGQRQLLCLARALLKRPRVLVL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFASCYsDDIIALKNGEIVKADT 219
Cdd:cd03369 150 DEATASIDYATDALIQKTIREEFT--NSTILTIAHRLRTIIDY-DKILVMDAGEVKEYDH 206
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
23-221 |
6.32e-15 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 73.23 E-value: 6.32e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 23 DIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLA---KKLSILKQTNHTEMN--ITVEQLVn 97
Cdd:COG4608 40 DIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRELRplrRRMQMVFQDPYASLNprMTVGDII- 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 98 fgRFPYSKGRMKKEDyEQVEYALDLLQL----QSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMkhSV- 172
Cdd:COG4608 119 --AEPLRIHGLASKA-ERRERVAELLELvglrPEHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDV--SIq 193
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 807234162 173 -QIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV-KADTKD 221
Cdd:COG4608 194 aQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVeIAPRDE 244
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
2-196 |
6.96e-15 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 73.67 E-value: 6.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPI---------LKNINVdIQKGRLTSLIGPNGAGKSTLLSAVS-----RLFEYEKGTIKIE------ 61
Cdd:COG1245 66 ISIVNLPEELEEDPVhrygengfrLYGLPV-PKKGKVTGILGPNGIGKSTALKILSgelkpNLGDYDEEPSWDEvlkrfr 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 62 GKAVVDYKNDDLAKKLSILKQTNHTEMnI------TVEQLvnfgrfpyskgrMKKEDYE-QVEYALDLLQLQSIRHRNIK 134
Cdd:COG1245 145 GTELQDYFKKLANGEIKVAHKPQYVDL-IpkvfkgTVREL------------LEKVDERgKLDELAEKLGLENILDRDIS 211
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 135 TLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDI 196
Cdd:COG1245 212 ELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYQRLNVARLIRELAEE-GKYVLVVEHDL 272
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-215 |
6.97e-15 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 73.57 E-value: 6.97e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQN----KPILKNINVDIQKGRLTSLIGPNGAGKS-TLLSAVsRL----FEYEKGTIKIEGKAVVDYKND 71
Cdd:COG4172 6 LLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvTALSIL-RLlpdpAAHPSGSILFDGQDLLGLSER 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 72 DLAK----KLSILKQTNHTEMN--ITVE-QLVNFGRFpysKGRMKKEDYEQVeyALDLLQLQSIR----------HRnik 134
Cdd:COG4172 85 ELRRirgnRIAMIFQEPMTSLNplHTIGkQIAEVLRL---HRGLSGAAARAR--ALELLERVGIPdperrldaypHQ--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 135 tLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:COG4172 157 -LSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEI 235
|
.
gi 807234162 215 V 215
Cdd:COG4172 236 V 236
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
2-194 |
1.30e-14 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 71.14 E-value: 1.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE--KGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:TIGR01978 1 LKIKDLHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGHPSYEvtSGTILFKGQDLLELEPDERARAGLF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTE-----MNITVEQLVNFGRFPYSKGRMKKEDY-EQVEYALDLLQL-QSIRHRNIKT-LSGGQRQRAYIAMTIA 151
Cdd:TIGR01978 81 LAFQYPEEipgvsNLEFLRSALNARRSARGEEPLDLLDFeKLLKEKLALLDMdEEFLNRSVNEgFSGGEKKRNEILQMAL 160
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 807234162 152 QDTDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLH 194
Cdd:TIGR01978 161 LEPKLAILDEIDSGLDIDALKIVAEGINRL-REPDRSFLIITH 202
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
16-226 |
2.08e-14 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 72.67 E-value: 2.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQ-----TNHTEMNi 90
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIPQdpvlfSGSLRMN- 1379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 tveqLVNFGRfpYSKgrmkkedyEQVEYALDLLQLQS--------IRHR---NIKTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:TIGR00957 1380 ----LDPFSQ--YSD--------EEVWWALELAHLKTfvsalpdkLDHEcaeGGENLSVGQRQLVCLARALLRKTKILVL 1445
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSdDIIALKNGEIVKADTKDNVIQA 226
Cdd:TIGR00957 1446 DEATAAVDLETDNLIQSTIRTQFEDC--TVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLQQ 1509
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-245 |
2.95e-14 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 71.96 E-value: 2.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKN--DDLAKKLS 78
Cdd:PRK10762 4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKE-VTFNGpkSSQEAGIG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 ILkqtnHTEMNI----TVEQLVNFGRFPYSK-GRMK-KEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:PRK10762 83 II----HQELNLipqlTIAENIFLGREFVNRfGRIDwKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDIN--FASCysDDIIALKNGEI-----VKADTKDNVIQ 225
Cdd:PRK10762 159 ESKVIIMDEPTDALTDTETESLFRVIREL-KSQGRGIVYISHRLKeiFEIC--DDVTVFRDGQFiaereVADLTEDSLIE 235
|
250 260
....*....|....*....|
gi 807234162 226 AEILKQLYEMDVHIEEIRGQ 245
Cdd:PRK10762 236 MMVGRKLEDQYPRLDKAPGE 255
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
19-212 |
3.48e-14 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 70.02 E-value: 3.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 19 NINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKlSILKQTNHT----EM----NI 90
Cdd:PRK11300 23 NVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARM-GVVRTFQHVrlfrEMtvieNL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 TVEQ--LVNFGRFPyskGRMKKEDY-----EQVEYA---LDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:PRK11300 102 LVAQhqQLKTGLFS---GLLKTPAFrraesEALDRAatwLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLD 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNG 212
Cdd:PRK11300 179 EPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQG 230
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
16-200 |
3.58e-14 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 69.84 E-value: 3.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGK--------AVVDYKNddlaKKLSILKQTNHTE 87
Cdd:PRK11629 24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQpmsklssaAKAELRN----QKLGFIYQFHHLL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 88 MNITVEQLVnfgRFPYSKGRMKKEdyEQVEYALDLLQLQSIRHRN---IKTLSGGQRQRAYIAMTIAQDTDYILLDEPLN 164
Cdd:PRK11629 100 PDFTALENV---AMPLLIGKKKPA--EINSRALEMLAAVGLEHRAnhrPSELSGGERQRVAIARALVNNPRLVLADEPTG 174
|
170 180 190
....*....|....*....|....*....|....*.
gi 807234162 165 NLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAS 200
Cdd:PRK11629 175 NLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAK 210
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
13-215 |
4.10e-14 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 71.39 E-value: 4.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQtnHTEM-NIT 91
Cdd:COG5265 370 ERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRAAIGIVPQ--DTVLfNDT 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVNFGRFPYSKgrmkkedyEQVEYALDLLQLQS-IRH-----------RNIKtLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:COG5265 448 IAYNIAYGRPDASE--------EEVEAAARAAQIHDfIESlpdgydtrvgeRGLK-LSGGEKQRVAIARTLLKNPPILIF 518
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLH------DinfascySDDIIALKNGEIV 215
Cdd:COG5265 519 DEATSALDSRTERAIQAALREVAR--GRTTLVIAHrlstivD-------ADEILVLEAGRIV 571
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
9-215 |
4.81e-14 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 68.83 E-value: 4.81e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 9 KAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEyekGTIKIEGKavVDYKNDDLAKKLSILKQT----- 83
Cdd:cd03233 15 KGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTE---GNVSVEGD--IHYNGIPYKEFAEKYPGEiiyvs 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 84 -NHTEM-NITVEQLVNFGrfpyskgrmkkedyeqveyaldlLQLQSirHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:cd03233 90 eEDVHFpTLTVRETLDFA-----------------------LRCKG--NEFVRGISGGERKRVSIAEALVSRASVLCWDN 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKDLNKTivivlhdiNFASCYS---------DDIIALKNGEIV 215
Cdd:cd03233 145 STRGLDSSTALEILKCIRTMADVLKTT--------TFVSLYQasdeiydlfDKVLVLYEGRQI 199
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
14-241 |
5.88e-14 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 71.55 E-value: 5.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSA-VSRLFEYEKGTIKIEGKavVDYknddlAKKLSILkqtnhteMNITV 92
Cdd:PLN03232 630 KPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAmLGELSHAETSSVVIRGS--VAY-----VPQVSWI-------FNATV 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNFGRFPYSKGRMKKEDYEQVEYALDLL---QLQSIRHRNIkTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMK 169
Cdd:PLN03232 696 RENILFGSDFESERYWRAIDVTALQHDLDLLpgrDLTEIGERGV-NISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAH 774
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 170 HSVQIMQTLRRlcKDLN-KTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQAEIL-KQLYE----MDVHIEE 241
Cdd:PLN03232 775 VAHQVFDSCMK--DELKgKTRVLVTNQLHFLP-LMDRIILVSEGMIKEEGTFAELSKSGSLfKKLMEnagkMDATQEV 849
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
12-212 |
6.58e-14 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 68.04 E-value: 6.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFE--YEKGTIKIEGKAvvdyKNDDLAKKLSILKQTNHTEMN 89
Cdd:cd03232 18 GKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTagVITGEILINGRP----LDKNFQRSTGYVEQQDVHSPN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 90 ITVEQLVNFgrfpyskgrmkkedyeqveyaldllqlqsirHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMK 169
Cdd:cd03232 94 LTVREALRF-------------------------------SALLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQ 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 807234162 170 HSVQIMQTLRRLCkDLNKTIVIVLH----DInFAscYSDDIIALKNG 212
Cdd:cd03232 143 AAYNIVRFLKKLA-DSGQAILCTIHqpsaSI-FE--KFDRLLLLKRG 185
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
15-227 |
8.54e-14 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 70.78 E-value: 8.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTnhtemNITVEQ 94
Cdd:PLN03232 1250 PVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQS-----PVLFSG 1324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGRFPYSkgrmKKEDYEQVEyALDLLQLQSIRHRNI-----------KTLSGGQRQRAYIAMTIAQDTDYILLDEPL 163
Cdd:PLN03232 1325 TVRFNIDPFS----EHNDADLWE-ALERAHIKDVIDRNPfgldaevseggENFSVGQRQLLSLARALLRRSKILVLDEAT 1399
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 164 NNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDIN-FASCysDDIIALKNGEIVKADTKDNVIQAE 227
Cdd:PLN03232 1400 ASVDVRTDSLIQRTIREEFKSC--TMLVIAHRLNtIIDC--DKILVLSSGQVLEYDSPQELLSRD 1460
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
15-241 |
9.25e-14 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 70.74 E-value: 9.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVsrLFEYEKGTIKIEGKAVVDYknddLAKKLSIlkqtnhteMNITVEQ 94
Cdd:TIGR00957 652 PTLNGITFSIPEGALVAVVGQVGCGKSSLLSAL--LAEMDKVEGHVHMKGSVAY----VPQQAWI--------QNDSLRE 717
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGRfpyskgRMKKEDYEQVEYALDLLQLQSIRHRNIKT--------LSGGQRQRAYIAMTIAQDTDYILLDEPLNNL 166
Cdd:TIGR00957 718 NILFGK------ALNEKYYQQVLEACALLPDLEILPSGDRTeigekgvnLSGGQKQRVSLARAVYSNADIYLFDDPLSAV 791
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 167 DM---KHSVQIMQTLRRLCKdlNKTIVIVLHDINFAScYSDDIIALKNGEIVKADTKDNVIQ-----AEILKQLY--EMD 236
Cdd:TIGR00957 792 DAhvgKHIFEHVIGPEGVLK--NKTRILVTHGISYLP-QVDVIIVMSGGKISEMGSYQELLQrdgafAEFLRTYApdEQQ 868
|
....*
gi 807234162 237 VHIEE 241
Cdd:TIGR00957 869 GHLED 873
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
14-210 |
9.39e-14 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 68.45 E-value: 9.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAvsrLFEYEKGTikiEGKAVVDYKNDDLAKKLSIlkqtnhtemnitVE 93
Cdd:COG2401 43 RYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRL---LAGALKGT---PVAGCVDVPDNQFGREASL------------ID 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 94 QLVnfgrfpyskgrmKKEDYEQVEYALDLLQL---QSIRhRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKH 170
Cdd:COG2401 105 AIG------------RKGDFKDAVELLNAVGLsdaVLWL-RRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQT 171
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 807234162 171 SVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALK 210
Cdd:COG2401 172 AKRVARNLQKLARRAGITLVVATHHYDVIDDLQPDLLIFV 211
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1-215 |
1.19e-13 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 67.98 E-value: 1.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKA-IQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDD---LAKK 76
Cdd:PRK10908 1 MIRFEHVSKAyLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREvpfLRRQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEMNITVEQLVNFgrfPYSKGRMKKEDYEQ-VEYALDLLQLQSiRHRNIKT-LSGGQRQRAYIAMTIAQDT 154
Cdd:PRK10908 81 IGMIFQDHHLLMDRTVYDNVAI---PLIIAGASGDDIRRrVSAALDKVGLLD-KAKNFPIqLSGGEQQRVGIARAVVNKP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 155 DYILLDEPLNNLDMKHSVQIMqtlrRLCKDLNKTIVIVL---HDINFASCYSDDIIALKNGEIV 215
Cdd:PRK10908 157 AVLLADEPTGNLDDALSEGIL----RLFEEFNRVGVTVLmatHDIGLISRRSYRMLTLSDGHLH 216
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
19-196 |
1.93e-13 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 68.98 E-value: 1.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 19 NINVDIQKGRLTSLIGPNGAGKST-------LLSAVSRLfeyeKGTIKIEGKAVVDYKNDDL----AKKLSILKQTNHTE 87
Cdd:PRK09473 34 DLNFSLRAGETLGIVGESGSGKSQtafalmgLLAANGRI----GGSATFNGREILNLPEKELnklrAEQISMIFQDPMTS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 88 MN--ITV-EQLVNFgrFPYSKGRMKKEDYEQVEYALDLLQLQSIRHRnIKT----LSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:PRK09473 110 LNpyMRVgEQLMEV--LMLHKGMSKAEAFEESVRMLDAVKMPEARKR-MKMypheFSGGMRQRVMIAMALLCRPKLLIAD 186
|
170 180 190
....*....|....*....|....*....|....*.
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDI 196
Cdd:PRK09473 187 EPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDL 222
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
5-233 |
2.13e-13 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 67.61 E-value: 2.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 5 KNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAV------------VDYkndd 72
Cdd:PRK10895 7 KNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDIsllplhararrgIGY---- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 LAKKLSILKQTNHTEMNITVEQLvnfgrfpySKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:PRK10895 83 LPQEASIFRRLSVYDNLMAVLQI--------RDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDI--NFASCYSDDIIAlkNGEIVKADTKDNVIQAEILK 230
Cdd:PRK10895 155 NPKFILLDEPFAGVDPISVIDIKRIIEHL-RDSGLGVLITDHNVreTLAVCERAYIVS--QGHLIAHGTPTEILQDEHVK 231
|
...
gi 807234162 231 QLY 233
Cdd:PRK10895 232 RVY 234
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1-226 |
2.17e-13 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 69.35 E-value: 2.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAI----QNKPILKNINVDIQKGRLTSLIGPNGAGKS-TLLSaVSRLF-----EYEKGTIKIEGKAVVDYKN 70
Cdd:PRK15134 5 LLAIENLSVAFrqqqTVRTVVNDVSLQIEAGETLALVGESGSGKSvTALS-ILRLLpsppvVYPSGDIRFHGESLLHASE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 71 DDL----AKKLSILKQTNHTEMNI--TVE-QLVNFgrfpYSKGRMKKEDYEQVEyALDLLQLQSIRHRNIK------TLS 137
Cdd:PRK15134 84 QTLrgvrGNKIAMIFQEPMVSLNPlhTLEkQLYEV----LSLHRGMRREAARGE-ILNCLDRVGIRQAAKRltdyphQLS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 138 GGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKA 217
Cdd:PRK15134 159 GGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQ 238
|
....*....
gi 807234162 218 DTKDNVIQA 226
Cdd:PRK15134 239 NRAATLFSA 247
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
27-182 |
3.60e-13 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 66.36 E-value: 3.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 27 GRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDDLAKKLSILKQTNHTEMNITVEQLVNFGRFPYSKg 106
Cdd:cd03231 26 GEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGP-LDFQRDSIARGLLYLGHAPGIKTTLSVLENLRFWHADHSD- 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 107 rmkkedyEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLC 182
Cdd:cd03231 104 -------EQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGHC 172
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
15-212 |
3.75e-13 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 69.17 E-value: 3.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavvdyknddlakkLSILKQTNHTeMNITVEQ 94
Cdd:TIGR01271 440 PVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-------------ISFSPQTSWI-MPGTIKD 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGrFPYSKGRmkkedYEQVEYALDLLQLQSIRHRNIK--------TLSGGQRQRAYIAMTIAQDTDYILLDEPLNNL 166
Cdd:TIGR01271 506 NIIFG-LSYDEYR-----YTSVIKACQLEEDIALFPEKDKtvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHL 579
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 807234162 167 DMKHSVQIMQtlRRLCKDL-NKTIVIVLHDINFAScYSDDIIALKNG 212
Cdd:TIGR01271 580 DVVTEKEIFE--SCLCKLMsNKTRILVTSKLEHLK-KADKILLLHEG 623
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
2-196 |
4.76e-13 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 68.30 E-value: 4.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPI---------LKNINVdIQKGRLTSLIGPNGAGKSTLLSAVS-----RLFEYEKGTIKIE------ 61
Cdd:PRK13409 66 ISIVNLPEELEEEPVhrygvngfkLYGLPI-PKEGKVTGILGPNGIGKTTAVKILSgelipNLGDYEEEPSWDEvlkrfr 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 62 GKAVVDYKNDDLAKKLSILKQTNHtemnitVEQLVNfgrfpYSKGR----MKKEDYEQV-EYALDLLQLQSIRHRNIKTL 136
Cdd:PRK13409 145 GTELQNYFKKLYNGEIKVVHKPQY------VDLIPK-----VFKGKvrelLKKVDERGKlDEVVERLGLENILDRDISEL 213
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 137 SGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDI 196
Cdd:PRK13409 214 SGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQRLNVARLIRELAE--GKYVLVVEHDL 271
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
16-226 |
4.82e-13 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 66.64 E-value: 4.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdyknddlakklSILkqtnhtEMN------ 89
Cdd:COG1134 41 ALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRVS------------ALL------ELGagfhpe 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 90 ITVEQLVnfgrfpYSKGR---MKKEDYEQ-VEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNN 165
Cdd:COG1134 103 LTGRENI------YLNGRllgLSRKEIDEkFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVATAVDPDILLVDEVLAV 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 166 LD---MKHSVQIMQTLRrlckDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQA 226
Cdd:COG1134 177 GDaafQKKCLARIRELR----ESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
19-223 |
4.93e-13 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 67.59 E-value: 4.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 19 NINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDdlakklsilkqtnhteMNITVEQLvNF 98
Cdd:PRK11144 16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKG----------------ICLPPEKR-RI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 99 G------R-FP-YS-KGR----MKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNN 165
Cdd:PRK11144 79 GyvfqdaRlFPhYKvRGNlrygMAKSMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLAS 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 166 LDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV 223
Cdd:PRK11144 159 LDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEV 216
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
17-195 |
5.59e-13 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 66.13 E-value: 5.59e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTL----------------LSAVSRLF--EYEKGTI-KIEGkavvdyknddLAKKL 77
Cdd:cd03270 11 LKNVDVDIPRNKLVVITGVSGSGKSSLafdtiyaegqrryvesLSAYARQFlgQMDKPDVdSIEG----------LSPAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SI-LKQTNHTEMNI--TVEQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQLQsirhRNIKTLSGGQRQRAYIAMTIAQDT 154
Cdd:cd03270 81 AIdQKTTSRNPRSTvgTVTEIYDYLRLLFARVGIRERLGFLVDVGLGYLTLS----RSAPTLSGGEAQRIRLATQIGSGL 156
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 807234162 155 DYIL--LDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHD 195
Cdd:cd03270 157 TGVLyvLDEPSIGLHPRDNDRLIETLKRL-RDLGNTVLVVEHD 198
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
15-227 |
8.83e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 67.84 E-value: 8.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTnhtemNITVEQ 94
Cdd:PLN03130 1253 PVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIPQA-----PVLFSG 1327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGRFPYSkgrmKKEDYEQVEyALDLLQLQSIRHRNIKTL-----------SGGQRQRAYIAMTIAQDTDYILLDEPL 163
Cdd:PLN03130 1328 TVRFNLDPFN----EHNDADLWE-SLERAHLKDVIRRNSLGLdaevseagenfSVGQRQLLSLARALLRRSKILVLDEAT 1402
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 164 NNLDMKHSVQIMQTLR---RLCkdlnkTIVIVLHDIN-FASCysDDIIALKNGEIVKADTKDNVIQAE 227
Cdd:PLN03130 1403 AAVDVRTDALIQKTIReefKSC-----TMLIIAHRLNtIIDC--DRILVLDAGRVVEFDTPENLLSNE 1463
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
2-181 |
1.23e-12 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 67.07 E-value: 1.23e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIeGKAV----VDYKNDDLAKK- 76
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETVklayVDQSRDALDPNk 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 ---------LSILKQTNHtEMN----ItveqlvnfGRFPYSKGRMKKedyeqveyaldllqlqsirhrNIKTLSGGQRQR 143
Cdd:PRK11819 404 tvweeisggLDIIKVGNR-EIPsrayV--------GRFNFKGGDQQK---------------------KVGVLSGGERNR 453
|
170 180 190
....*....|....*....|....*....|....*...
gi 807234162 144 AYIAMTIAQDTDYILLDEPLNNLDmkhsvqiMQTLRRL 181
Cdd:PRK11819 454 LHLAKTLKQGGNVLLLDEPTNDLD-------VETLRAL 484
|
|
| NHLM_micro_ABC1 |
TIGR03796 |
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ... |
2-227 |
1.50e-12 |
|
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 66.89 E-value: 1.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLD--KAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:TIGR03796 478 VELRNITfgYSPLEPPLIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIPREVLANSVAM 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQT----------NHTEMNITV--EQLVNFGRfpyskgrmkkeD---YEQV-----EYALDLLQlqsiRHRNiktLSGG 139
Cdd:TIGR03796 558 VDQDiflfegtvrdNLTLWDPTIpdADLVRACK-----------DaaiHDVItsrpgGYDAELAE----GGAN---LSGG 619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 140 QRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRL-CkdlnkTIVIVLHDIN-FASCysDDIIALKNGEIVKA 217
Cdd:TIGR03796 620 QRQRLEIARALVRNPSILILDEATSALDPETEKIIDDNLRRRgC-----TCIIVAHRLStIRDC--DEIIVLERGKVVQR 692
|
250
....*....|
gi 807234162 218 DTKDNVIQAE 227
Cdd:TIGR03796 693 GTHEELWAVG 702
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
7-215 |
2.19e-12 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 66.27 E-value: 2.19e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 7 LDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEkGTIKIEGKAVVDYKNDDL---AKKLSILKQT 83
Cdd:PRK15134 292 LKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLINSQ-GEIWFDGQPLHNLNRRQLlpvRHRIQVVFQD 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 84 NHTEMN--ITVEQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQLQ-SIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:PRK15134 371 PNSSLNprLNVLQIIEEGLRVHQPTLSAAQREQQVIAVMEEVGLDpETRHRYPAEFSGGQRQRIAIARALILKPSLIILD 450
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK15134 451 EPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVV 505
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
14-221 |
3.96e-12 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 65.96 E-value: 3.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEgkavvdyknddlaKKLSILKQTNHTeMNITVE 93
Cdd:PTZ00243 673 KVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAE-------------RSIAYVPQQAWI-MNATVR 738
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 94 QLVNFgrfpyskgrMKKEDYEQVEYALDLLQLQS------------IRHRNIkTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:PTZ00243 739 GNILF---------FDEEDAARLADAVRVSQLEAdlaqlgggleteIGEKGV-NLSGGQKARVSLARAVYANRDVYLLDD 808
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 162 PLNNLDMKHSVQIMQT--LRRLCkdlNKTIVIVLHDINFAScYSDDIIALKNGEIVKA-DTKD 221
Cdd:PTZ00243 809 PLSALDAHVGERVVEEcfLGALA---GKTRVLATHQVHVVP-RADYVVALGDGRVEFSgSSAD 867
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
1-194 |
4.20e-12 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 64.04 E-value: 4.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE--KGTIKIEGKAVVDYKNDDLAKK-- 76
Cdd:PRK09580 1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEvtGGTVEFKGKDLLELSPEDRAGEgi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 -------LSILKQTNHTEMNITVEQLVNFgRFPYSKGRMKKEDYeqVEYALDLLQL-QSIRHRNIKT-LSGGQRQRAYIA 147
Cdd:PRK09580 81 fmafqypVEIPGVSNQFFLQTALNAVRSY-RGQEPLDRFDFQDL--MEEKIALLKMpEDLLTRSVNVgFSGGEKKRNDIL 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 807234162 148 MTIAQDTDYILLDEPLNNLDMKhSVQIMQTLRRLCKDLNKTIVIVLH 194
Cdd:PRK09580 158 QMAVLEPELCILDESDSGLDID-ALKIVADGVNSLRDGKRSFIIVTH 203
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
12-194 |
5.02e-12 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 62.56 E-value: 5.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 12 QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYknddlakklsiLKQTnhtemnit 91
Cdd:cd03223 12 DGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGEDLLF-----------LPQR-------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 veqlvnfgrfPY-SKGRMKkedyEQVEYALDllqlqsirhrniKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDmkh 170
Cdd:cd03223 73 ----------PYlPLGTLR----EQLIYPWD------------DVLSGGEQQRLAFARLLLHKPKFVFLDEATSALD--- 123
|
170 180
....*....|....*....|....
gi 807234162 171 sVQIMQTLRRLCKDLNKTIVIVLH 194
Cdd:cd03223 124 -EESEDRLYQLLKELGITVISVGH 146
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
16-194 |
5.93e-12 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 65.52 E-value: 5.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSrlfEYEKGTIKIEGKAVVDYKNDDLAKKLSI---LKQTNHTEMNITV 92
Cdd:TIGR00956 778 ILNNVDGWVKPGTLTALMGASGAGKTTLLNVLA---ERVTTGVITGGDRLVNGRPLDSSFQRSIgyvQQQDLHLPTSTVR 854
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKT----LSGGQRQRAYIAMTIAQDTDYIL-LDEPLNNLD 167
Cdd:TIGR00956 855 ESLRFSAYLRQPKSVSKSEKMEYVEEVIKLLEMESYADAVVGVpgegLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLD 934
|
170 180
....*....|....*....|....*..
gi 807234162 168 MKHSVQIMQTLRRLCkDLNKTIVIVLH 194
Cdd:TIGR00956 935 SQTAWSICKLMRKLA-DHGQAILCTIH 960
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
6-243 |
7.82e-12 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 63.96 E-value: 7.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 6 NLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRL------FEYEkGTIKIEGKAVVDYKND-DLAKKLS 78
Cdd:PRK14271 26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMndkvsgYRYS-GDVLLGGRSIFNYRDVlEFRRRVG 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 79 IL-KQTNHTEMNITVEQLVNFgrfpYSKGRMKKEDYEQVEYA--LDLLQLQSIRHRNIKT---LSGGQRQRAYIAMTIAQ 152
Cdd:PRK14271 105 MLfQRPNPFPMSIMDNVLAGV----RAHKLVPRKEFRGVAQArlTEVGLWDAVKDRLSDSpfrLSGGQQQLLCLARTLAV 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDnviqaeilkQL 232
Cdd:PRK14271 181 NPEVLLLDEPTSALDPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGPTE---------QL 249
|
250
....*....|.
gi 807234162 233 YEMDVHIEEIR 243
Cdd:PRK14271 250 FSSPKHAETAR 260
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
15-213 |
7.84e-12 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 63.72 E-value: 7.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavvdyknddlakkLSILKQTNHTeMNITVEQ 94
Cdd:cd03291 51 PVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-------------ISFSSQFSWI-MPGTIKE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 95 LVNFGrFPYSKGRMKKEdYEQVEYALDLLQL----QSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKH 170
Cdd:cd03291 117 NIIFG-VSYDEYRYKSV-VKACQLEEDITKFpekdNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFT 194
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 807234162 171 SVQIMQTLrrLCKDL-NKTIVIVLHDINFAScYSDDIIALKNGE 213
Cdd:cd03291 195 EKEIFESC--VCKLMaNKTRILVTSKMEHLK-KADKILILHEGS 235
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-223 |
8.27e-12 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 63.41 E-value: 8.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavvDYKNDDLAK----K 76
Cdd:PRK11701 6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMR---DGQLRDLYAlseaE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTN----HTE------MNIT-----VEQLVNFGRFPYSKGRMKKEDY-EQVEYALDLLQLQSirhrniKTLSGGQ 140
Cdd:PRK11701 83 RRRLLRTEwgfvHQHprdglrMQVSaggniGERLMAVGARHYGDIRATAGDWlERVEIDAARIDDLP------TTFSGGM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 141 RQRAYIAMTIAQDTDYILLDEPLNNLDMkhSVQ--IMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKAD 218
Cdd:PRK11701 157 QQRLQIARNLVTHPRLVFMDEPTGGLDV--SVQarLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESG 234
|
....*
gi 807234162 219 TKDNV 223
Cdd:PRK11701 235 LTDQV 239
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
4-214 |
8.87e-12 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 63.16 E-value: 8.87e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 4 IKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIkIEGKAVVDYKNDDlakklsilkqt 83
Cdd:PRK11247 15 LNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL-LAGTAPLAEARED----------- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 84 nhTEMNITVEQLVNFGRFPYSKGRMKKEDY-EQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEP 162
Cdd:PRK11247 83 --TRLMFQDARLLPWKKVIDNVGLGLKGQWrDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 807234162 163 LNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:PRK11247 161 LGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
17-214 |
9.39e-12 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 64.61 E-value: 9.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHtemniTVEQLV 96
Cdd:PRK10522 339 VGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDYRKLFSAVFTDFH-----LFDQLL 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 97 NFGRFPyskgrmkkEDYEQVEYALDLLQLQSI------RHRNIKtLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKH 170
Cdd:PRK10522 414 GPEGKP--------ANPALVEKWLERLKMAHKleledgRISNLK-LSKGQKKRLALLLALAEERDILLLDEWAADQDPHF 484
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 807234162 171 SVQIMQTLRRLCKDLNKTIVIVLHDINFAScYSDDIIALKNGEI 214
Cdd:PRK10522 485 RREFYQVLLPLLQEMGKTIFAISHDDHYFI-HADRLLEMRNGQL 527
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
4-194 |
1.01e-11 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 64.52 E-value: 1.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 4 IKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE--KGTIKIEGKAVVdyknDDLAKKLSILK 81
Cdd:PLN03211 71 ISDETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPT----KQILKRTGFVT 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLVNFG---RFPYSKGRMKKEDY-EQVEYALDLLQLQS--IRHRNIKTLSGGQRQRAYIAMTIAQDTD 155
Cdd:PLN03211 147 QDDILYPHLTVRETLVFCsllRLPKSLTKQEKILVaESVISELGLTKCENtiIGNSFIRGISGGERKRVSIAHEMLINPS 226
|
170 180 190
....*....|....*....|....*....|....*....
gi 807234162 156 YILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLH 194
Cdd:PLN03211 227 LLILDEPTSGLDATAAYRLVLTLGSLAQK-GKTIVTSMH 264
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1-179 |
1.19e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 62.27 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdykNDDLA---KKL 77
Cdd:PRK13540 1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI----KKDLCtyqKQL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 78 SILKQTNHTEMNITVEQLVNFGrFPYSKGRMkkedyeQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYI 157
Cdd:PRK13540 77 CFVGHRSGINPYLTLRENCLYD-IHFSPGAV------GITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLW 149
|
170 180
....*....|....*....|..
gi 807234162 158 LLDEPLNNLDMKHSVQIMQTLR 179
Cdd:PRK13540 150 LLDEPLVALDELSLLTIITKIQ 171
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-226 |
1.36e-11 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 63.92 E-value: 1.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYkNDDLAKKLSI- 79
Cdd:PRK15439 11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARL-TPAKAHQLGIy 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 -LKQTNHTEMNITVEQLVNFGrFPYSKGRMKKedyeqVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:PRK15439 90 lVPQEPLLFPNLSVKENILFG-LPKRQASMQK-----MKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILI 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKAD-----TKDNVIQA 226
Cdd:PRK15439 164 LDEPTASLTPAETERLFSRIREL-LAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGktadlSTDDIIQA 235
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
16-212 |
1.44e-11 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 64.10 E-value: 1.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVS--RLFEYEKGTIKIEGkavVDYKNDDLAKKLSILKQTNHTEMNITV- 92
Cdd:PLN03140 895 LLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAgrKTGGYIEGDIRISG---FPKKQETFARISGYCEQNDIHSPQVTVr 971
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLV--NFGRFPysKGRMKKEDYEQVEYALDLLQLQSIRHR-----NIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNN 165
Cdd:PLN03140 972 ESLIysAFLRLP--KEVSKEEKMMFVDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSG 1049
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 807234162 166 LDMKHSVQIMQTLRRLCkDLNKTIVIVLH--DINFASCYsDDIIALKNG 212
Cdd:PLN03140 1050 LDARAAAIVMRTVRNTV-DTGRTVVCTIHqpSIDIFEAF-DELLLMKRG 1096
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
14-230 |
1.52e-11 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 63.83 E-value: 1.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQT----NHT-EM 88
Cdd:PRK13657 348 RQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRRNIAVVFQDaglfNRSiED 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 89 NITVeqlvnfgrfpyskGRMKKEDYEQVE-----YALDLLQLQSIRHRNI-----KTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:PRK13657 428 NIRV-------------GRPDATDEEMRAaaeraQAHDFIERKPDGYDTVvgergRQLSGGERQRLAIARALLKDPPILI 494
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLH---DINFAscysDDIIALKNGEIVKADTKDNVIQ-----AEILK 230
Cdd:PRK13657 495 LDEATSALDVETEAKVKAALDELMK--GRTTFIIAHrlsTVRNA----DRILVFDNGRVVESGSFDELVArggrfAALLR 568
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-221 |
2.16e-11 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 63.12 E-value: 2.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDK------AiqnkpiLKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKNDDLA 74
Cdd:COG3845 5 ALELRGITKrfggvvA------NDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKP-VRIRSPRDA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 75 KKLSILkqtnhteM---------NITV-EQLV------NFGRFPYSKGRMKKEDYEQvEY--ALDLlqlqsirHRNIKTL 136
Cdd:COG3845 78 IALGIG-------MvhqhfmlvpNLTVaENIVlgleptKGGRLDRKAARARIRELSE-RYglDVDP-------DAKVEDL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 137 SGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:COG3845 143 SVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTVLRRGKVVG 221
|
....*.
gi 807234162 217 -ADTKD 221
Cdd:COG3845 222 tVDTAE 227
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
2-226 |
2.26e-11 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 62.02 E-value: 2.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLdkAIQ-NKPILKNINVDIQKGRLTSLIGPNGAGKS--------TLLSAVSRLfeyeKGTIKIEGKAVVdyKNDD 72
Cdd:PRK10418 5 IELRNI--ALQaAQPLVHGVSLTLQRGRVLALVGGSGSGKSltcaaalgILPAGVRQT----AGRVLLDGKPVA--PCAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 LAKKLSILKQT-----N--HTEMNITVEQLVNFGRFPyskgrmkkeDYEQVEYALDLLQLQSiRHRNIKT----LSGGQR 141
Cdd:PRK10418 77 RGRKIATIMQNprsafNplHTMHTHARETCLALGKPA---------DDATLTAALEAVGLEN-AARVLKLypfeMSGGML 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 142 QRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKD 221
Cdd:PRK10418 147 QRMMIALALLCEAPFIIADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVE 226
|
....*
gi 807234162 222 NVIQA 226
Cdd:PRK10418 227 TLFNA 231
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
19-224 |
2.57e-11 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 63.28 E-value: 2.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 19 NINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIE-GKAVVD-----YKNDDLAKK-LSILKQT-------- 83
Cdd:TIGR03269 302 NVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvGDEWVDmtkpgPDGRGRAKRyIGILHQEydlyphrt 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 84 ---NHTEmNITVEqlvnfgrFPYSKGRMKKEdYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:TIGR03269 382 vldNLTE-AIGLE-------LPDELARMKAV-ITLKMVGFDEEKAEEILDKYPDELSEGERHRVALAQVLIKEPRIVILD 452
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:TIGR03269 453 EPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIV 516
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-227 |
3.04e-11 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 62.81 E-value: 3.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:PRK10790 341 IDIDNVSFAYRDdNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGVAMV 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQ-----TNHTEMNITVeqlvnfgrfpyskGRMKKEdyEQVEYALDLLQLQS-IR------HRNI----KTLSGGQRQRA 144
Cdd:PRK10790 421 QQdpvvlADTFLANVTL-------------GRDISE--EQVWQALETVQLAElARslpdglYTPLgeqgNNLSVGQKQLL 485
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINfASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:PRK10790 486 ALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVRE--HTTLVVIAHRLS-TIVEADTILVLHRGQAVEQGTHQQLL 562
|
...
gi 807234162 225 QAE 227
Cdd:PRK10790 563 AAQ 565
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
3-198 |
3.60e-11 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 62.66 E-value: 3.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKN------------ 70
Cdd:PRK11147 321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKLEVAYFDqhraeldpektv 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 71 -DDLAKKlsilKQTnhtemnITVeqlvnfgrfpysKGRMKkedyeqveYALDLLQ---LQSIRHRN-IKTLSGGQRQRAY 145
Cdd:PRK11147 401 mDNLAEG----KQE------VMV------------NGRPR--------HVLGYLQdflFHPKRAMTpVKALSGGERNRLL 450
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 807234162 146 IAMTIAQDTDYILLDEPLNNLDmkhsVQIMQTLRRLCKDLNKTIVIVLHDINF 198
Cdd:PRK11147 451 LARLFLKPSNLLILDEPTNDLD----VETLELLEELLDSYQGTVLLVSHDRQF 499
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
6-215 |
4.84e-11 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 61.24 E-value: 4.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 6 NLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvvdyknddlakkLSILKQTNH 85
Cdd:PRK10419 17 GLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEP------------LAKLNRAQR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 86 TEMNITVeQLV---NFGRF-P-YSKGRMKKE---------DYEQVEYALDLLQL----QSIRHRNIKTLSGGQRQRAYIA 147
Cdd:PRK10419 85 KAFRRDI-QMVfqdSISAVnPrKTVREIIREplrhllsldKAERLARASEMLRAvdldDSVLDKRPPQLSGGQLQRVCLA 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 148 MTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK10419 164 RALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIV 231
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-209 |
5.38e-11 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 61.64 E-value: 5.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDK-------------AIQN--------KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIK 59
Cdd:COG4586 1 IIEVENLSKtyrvyekepglkgALKGlfrreyreVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 60 IEGKavVDYKND-DLAKklsilkqtnhtemNITV-----EQL---------VNFGRFPYskgRMKKEDYEQ-VEYALDLL 123
Cdd:COG4586 81 VLGY--VPFKRRkEFAR-------------RIGVvfgqrSQLwwdlpaidsFRLLKAIY---RIPDAEYKKrLDELVELL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 124 QLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDInfascys 203
Cdd:COG4586 143 DLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDM------- 215
|
....*.
gi 807234162 204 DDIIAL 209
Cdd:COG4586 216 DDIEAL 221
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-233 |
5.44e-11 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 62.25 E-value: 5.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYE--KGTIKIEGKAVVdYKN--DDLAKK 76
Cdd:PRK13549 5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGtyEGEIIFEGEELQ-ASNirDTERAG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEMNITVEQLVNFGRFPYSKGRMkkeDYEQV----EYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQ 152
Cdd:PRK13549 84 IAIIHQELALVKELSVLENIFLGNEITPGGIM---DYDAMylraQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 153 DTDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEI---- 228
Cdd:PRK13549 161 QARLLILDEPTASLTESETAVLLDIIRDL-KAHGIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAGMTEDDIitmm 239
|
....*....
gi 807234162 229 ----LKQLY 233
Cdd:PRK13549 240 vgreLTALY 248
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
4-215 |
8.52e-11 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 61.67 E-value: 8.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 4 IKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvVDYKN--DDLAKKLSILk 81
Cdd:PRK10982 1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKE-IDFKSskEALENGISMV- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 qtnHTEMNITVEQLVN----FGRFPySKGRMKKED--YEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTD 155
Cdd:PRK10982 79 ---HQELNLVLQRSVMdnmwLGRYP-TKGMFVDQDkmYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAK 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 156 YILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK10982 155 IVIMDEPTSSLTEKEVNHLFTIIRKL-KERGCGIVYISHKMEEIFQLCDEITILRDGQWI 213
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-212 |
1.13e-10 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 59.76 E-value: 1.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKA----IQNK---PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIkiegkaVVDYKND-- 71
Cdd:COG4778 4 LLEVENLSKTftlhLQGGkrlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSI------LVRHDGGwv 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 72 DLAK-----KLSILKQT------------NHTEMNITVEQLVnfgrfpySKGRMKKEDYEQveyALDLLqlqsiRHRNIK 134
Cdd:COG4778 78 DLAQaspreILALRRRTigyvsqflrvipRVSALDVVAEPLL-------ERGVDREEARAR---ARELL-----ARLNLP 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 135 ---------TLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDD 205
Cdd:COG4778 143 erlwdlppaTFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEA-KARGTAIIGIFHDEEVREAVADR 221
|
....*..
gi 807234162 206 IIALKNG 212
Cdd:COG4778 222 VVDVTPF 228
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
1-200 |
1.37e-10 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 59.41 E-value: 1.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAI----QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKI----------EGKAVV 66
Cdd:PRK10584 6 IVEVHHLKKSVgqgeHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLvgqplhqmdeEARAKL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 67 DYKNDDLAKKLSILKQTNHTEMNITVEQLVnfgrfpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYI 146
Cdd:PRK10584 86 RAKHVGFVFQSFMLIPTLNALENVELPALL--------RGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVAL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 147 AMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFAS 200
Cdd:PRK10584 158 ARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAA 211
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
4-198 |
1.89e-10 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 60.72 E-value: 1.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 4 IKNLDKAIQ-NKPILKNINVDIQKGRLTSLIGPNGAGKSTLL---SAVSRLFEYE---KGTIKI----------EGKAVV 66
Cdd:TIGR03719 7 MNRVSKVVPpKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLrimAGVDKDFNGEarpQPGIKVgylpqepqldPTKTVR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 67 DYKNDDLAKKLSILKQTNHTEMNITvEQLVNFGRFPYSKGRMKKE-------DYE-QVEYALDLLQLQSiRHRNIKTLSG 138
Cdd:TIGR03719 87 ENVEEGVAEIKDALDRFNEISAKYA-EPDADFDKLAAEQAELQEIidaadawDLDsQLEIAMDALRCPP-WDADVTKLSG 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 139 GQRQRAYIAMTIAQDTDYILLDEPLNNLDMKhSVqimQTLRRLCKDLNKTIVIVLHDINF 198
Cdd:TIGR03719 165 GERRRVALCRLLLSKPDMLLLDEPTNHLDAE-SV---AWLERHLQEYPGTVVAVTHDRYF 220
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
17-216 |
2.85e-10 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 60.25 E-value: 2.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAV---VDYKNDDLAKKLSILKQTNHTEMN--IT 91
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIdtlSPGKLQALRRDIQFIFQDPYASLDprQT 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 V-----EQLVNFGRFPyskgrmKKEDYEQVEYALDLLQLQSiRH--RNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLN 164
Cdd:PRK10261 420 VgdsimEPLRVHGLLP------GKAAAARVAWLLERVGLLP-EHawRYPHEFSGGQRQRICIARALALNPKVIIADEAVS 492
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 807234162 165 NLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVK 216
Cdd:PRK10261 493 ALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVE 544
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
17-207 |
2.87e-10 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 57.72 E-value: 2.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAvsrlfeyekgTIKIEGKavvdyknddlaKKLSILKQTNHTEMNITVEQLV 96
Cdd:cd03238 11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVNE----------GLYASGK-----------ARLISFLPKFSRNKLIFIDQLQ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 97 NFgrfpyskgrmkkedyeqVEYALDLLQLQsirhRNIKTLSGGQRQRAYIAMTIAQDTDYIL--LDEPLNNLDMKHSVQI 174
Cdd:cd03238 70 FL-----------------IDVGLGYLTLG----QKLSTLSGGELQRVKLASELFSEPPGTLfiLDEPSTGLHQQDINQL 128
|
170 180 190
....*....|....*....|....*....|...
gi 807234162 175 MQTLRRLcKDLNKTIVIVLHDINFaSCYSDDII 207
Cdd:cd03238 129 LEVIKGL-IDLGNTVILIEHNLDV-LSSADWII 159
|
|
| NHLM_micro_ABC2 |
TIGR03797 |
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ... |
15-232 |
5.13e-10 |
|
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 59.20 E-value: 5.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLsavsRL---FEY-EKGTIKIEGKAVVDYKNDDLAKKLSILKQtNHTEM-- 88
Cdd:TIGR03797 467 LILDDVSLQIEPGEFVAIVGPSGSGKSTLL----RLllgFETpESGSVFYDGQDLAGLDVQAVRRQLGVVLQ-NGRLMsg 541
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 89 ----NITveqlvnfGRFPYS------KGRMK--KEDYEQVEyaldlLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDY 156
Cdd:TIGR03797 542 sifeNIA-------GGAPLTldeaweAARMAglAEDIRAMP-----MGMHTVISEGGGTLSGGQRQRLLIARALVRKPRI 609
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 157 ILLDEPLNNLDMKHSVQIMQTLRRlckdLNKT-IVIV--LHDINFAscysDDIIALKNGEIVKADTKDNVIQAE-ILKQL 232
Cdd:TIGR03797 610 LLFDEATSALDNRTQAIVSESLER----LKVTrIVIAhrLSTIRNA----DRIYVLDAGRVVQQGTYDELMAREgLFAQL 681
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
15-215 |
6.09e-10 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 59.19 E-value: 6.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVV----------------DYKND---DLAK 75
Cdd:PRK11147 17 PLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVarlqqdpprnvegtvyDFVAEgieEQAE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 KLSILKQTNHTEMNITVEQLVNfgrfpyskgRMKKEDyEQVEYaLDLLQLQSIRHRNIKT-----------LSGGQRQRA 144
Cdd:PRK11147 97 YLKRYHDISHLVETDPSEKNLN---------ELAKLQ-EQLDH-HNLWQLENRINEVLAQlgldpdaalssLSGGWLRKA 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDmkhsVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK11147 166 ALGRALVSNPDVLLLDEPTNHLD----IETIEWLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDRGKLV 232
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
1-194 |
6.24e-10 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 59.05 E-value: 6.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQN-KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIegkavvdyknDDLAKKLSI 79
Cdd:COG4178 362 ALALEDLTLRTPDgRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR----------PAGARVLFL 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 ----------LKqtnhtemnitvEQLVnfgrFPYSKGRMKKEDYEQveyALDLLQLQSIRHR-NI-----KTLSGGQRQR 143
Cdd:COG4178 432 pqrpylplgtLR-----------EALL----YPATAEAFSDAELRE---ALEAVGLGHLAERlDEeadwdQVLSLGEQQR 493
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 807234162 144 AYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLH 194
Cdd:COG4178 494 LAFARLLLHKPDWLFLDEATSALDEENEAALYQLLREELPGT--TVISVGH 542
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-232 |
1.30e-09 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 57.91 E-value: 1.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLF---EYEkGTIKIEGKAVV-DYKNDDLAKK 76
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYphgTWD-GEIYWSGSPLKaSNIRDTERAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 77 LSILKQTNHTEMNITVEQLVNFG-RFPYSKGRMK-KEDYEQVEYALDLLQLQSIRH-RNIKTLSGGQRQRAYIAMTIAQD 153
Cdd:TIGR02633 80 IVIIHQELTLVPELSVAENIFLGnEITLPGGRMAyNAMYLRAKNLLRELQLDADNVtRPVGDYGGGQQQLVEIAKALNKQ 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 154 TDYILLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQL 232
Cdd:TIGR02633 160 ARLLILDEPSSSLTEKETEILLDIIRDL-KAHGVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMSTMSEDDIITMM 237
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
15-179 |
1.52e-09 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 56.21 E-value: 1.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKnDDLAKKLSILKQTNHTEMNITV-E 93
Cdd:TIGR01189 14 MLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQR-DEPHENILYLGHLPGLKPELSAlE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 94 QLVNFGRFPYSKGRMkkedyeqVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIA-MTIAQDTDYIlLDEPLNNLDMKHSV 172
Cdd:TIGR01189 93 NLHFWAAIHGGAQRT-------IEDALAAVGLTGFEDLPAAQLSAGQQRRLALArLWLSRRPLWI-LDEPTTALDKAGVA 164
|
....*..
gi 807234162 173 QIMQTLR 179
Cdd:TIGR01189 165 LLAGLLR 171
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
2-227 |
6.64e-09 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 54.91 E-value: 6.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQN--KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSI 79
Cdd:cd03288 20 IKIHDLCVRYENnlKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQtnhtemnitvEQLVNFGRFPYSKGRMKKEDYEQVEYALDLLQLQSIrhrnIKTLSG---------------GQRQRA 144
Cdd:cd03288 100 ILQ----------DPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNM----VKSLPGgldavvteggenfsvGQRQLF 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKhSVQIMQTLrRLCKDLNKTIVIVLHDINfASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:cd03288 166 CLARAFVRKSSILIMDEATASIDMA-TENILQKV-VMTAFADRTVVTIAHRVS-TILDADLVLVLSRGILVECDTPENLL 242
|
...
gi 807234162 225 QAE 227
Cdd:cd03288 243 AQE 245
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
136-207 |
6.92e-09 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 54.12 E-value: 6.92e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 136 LSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDII 207
Cdd:cd03222 72 LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIH 143
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
13-227 |
7.08e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 56.19 E-value: 7.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEK------------------------------------- 55
Cdd:PTZ00265 1180 NVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKNdhhivfknehtndmtneqdyqgdeeqnvgmknvnefs 1259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 56 -----------------GTIKIEGKAVVDYKNDDLAKKLSILKQtNHTEMNITVEQLVNFGrfpysKGRMKKEDYEQVE- 117
Cdd:PTZ00265 1260 ltkeggsgedstvfknsGKILLDGVDICDYNLKDLRNLFSIVSQ-EPMLFNMSIYENIKFG-----KEDATREDVKRACk 1333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 118 -YALD--LLQLQSIRHRNI----KTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIV 190
Cdd:PTZ00265 1334 fAAIDefIESLPNKYDTNVgpygKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTII 1413
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 807234162 191 IVLHDInfASCYSDDIIAL-----KNGEIVKAD-TKDNVIQAE 227
Cdd:PTZ00265 1414 TIAHRI--ASIKRSDKIVVfnnpdRTGSFVQAHgTHEELLSVQ 1454
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
3-230 |
7.61e-09 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 55.79 E-value: 7.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLdkaiQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVV---------------- 66
Cdd:COG1129 258 EVEGL----SVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRirsprdairagiayvp 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 67 -DYKNDDLAKKLSILKqtnhtemNITVEQLVNFGRFPY-SKGRMKKEdyeqveyALDLLQLQSIR----HRNIKTLSGGQ 140
Cdd:COG1129 334 eDRKGEGLVLDLSIRE-------NITLASLDRLSRGGLlDRRRERAL-------AEEYIKRLRIKtpspEQPVGNLSGGN 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 141 RQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIV-------LHdinfascYSDDIIALKNGE 213
Cdd:COG1129 400 QQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVIsselpelLG-------LSDRILVMREGR 471
|
250
....*....|....*..
gi 807234162 214 IVKADTKDNVIQAEILK 230
Cdd:COG1129 472 IVGELDREEATEEAIMA 488
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
14-191 |
8.18e-09 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 53.52 E-value: 8.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 14 KPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSrlfeyekgtikiegkavvdyknddlakklsilkqtnhtemnitve 93
Cdd:cd03227 8 PSYFVPNDVTFGEGSLTIITGPNGSGKSTILDAIG--------------------------------------------- 42
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 94 qLVNFGRFpySKGRMKKEDYEQVEYALDLLQLQSIRHRniktLSGGQRQRAYIAMTIA----QDTDYILLDEPLNNLDMK 169
Cdd:cd03227 43 -LALGGAQ--SATRRRSGVKAGCIVAAVSAELIFTRLQ----LSGGEKELSALALILAlaslKPRPLYILDEIDRGLDPR 115
|
170 180
....*....|....*....|..
gi 807234162 170 HSVQIMQTLRRLCKDLNKTIVI 191
Cdd:cd03227 116 DGQALAEAILEHLVKGAQVIVI 137
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
3-230 |
1.01e-08 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 55.18 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLDKAIQNKpiLKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQ 82
Cdd:PRK09700 267 EVRNVTSRDRKK--VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDAVKKGMAYIT 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 83 TNHTE----------MNITVEQLVNFGRFpysKGRM----KKEDYEQVEYALDLLQLQ-SIRHRNIKTLSGGQRQRAYIA 147
Cdd:PRK09700 345 ESRRDngffpnfsiaQNMAISRSLKDGGY---KGAMglfhEVDEQRTAENQRELLALKcHSVNQNITELSGGNQQKVLIS 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 148 MTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKA-DTKDNVIQA 226
Cdd:PRK09700 422 KWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQIlTNRDDMSEE 500
|
....
gi 807234162 227 EILK 230
Cdd:PRK09700 501 EIMA 504
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
2-215 |
1.60e-08 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 54.87 E-value: 1.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVS-----------RLFEYEKGTIKIEGKAVVDYKN 70
Cdd:PLN03073 178 IHMENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMAmhaidgipkncQILHVEQEVVGDDTTALQCVLN 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 71 DDLAKKLSILKQTNHTEMNITVEQLVNFGRfpySKGRMK---KED-----YEQVEYALDLLQLQS--------------- 127
Cdd:PLN03073 258 TDIERTQLLEEEAQLVAQQRELEFETETGK---GKGANKdgvDKDavsqrLEEIYKRLELIDAYTaearaasilaglsft 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 128 --IRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMkHSVQIMQTLrrLCKdLNKTIVIVLHDINFASCYSDD 205
Cdd:PLN03073 335 peMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL-HAVLWLETY--LLK-WPKTFIVVSHAREFLNTVVTD 410
|
250
....*....|
gi 807234162 206 IIALKNGEIV 215
Cdd:PLN03073 411 ILHLHGQKLV 420
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
136-226 |
1.66e-08 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 54.36 E-value: 1.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 136 LSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIV 215
Cdd:PRK11022 154 LSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVV 233
|
90
....*....|.
gi 807234162 216 KADTKDNVIQA 226
Cdd:PRK11022 234 ETGKAHDIFRA 244
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
17-237 |
2.19e-08 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 54.51 E-value: 2.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKqtnhtemNITVEQLV 96
Cdd:PRK13545 40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAALIAISSGLNGQLTGIE-------NIELKGLM 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 97 nfgrfpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQ 176
Cdd:PRK13545 113 --------MGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLD 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 807234162 177 TLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVK-ADTKDNVIQ-AEILKQLYEMDV 237
Cdd:PRK13545 185 KMNEF-KEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEyGDIKEVVDHyDEFLKKYNQMSV 246
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
1-230 |
2.40e-08 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 54.35 E-value: 2.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAiqNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYK-----NDDLAK 75
Cdd:PRK10982 250 ILEVRNLTSL--RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNaneaiNHGFAL 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 KLSILKQTN-HTEMNITVEQLV-NFGRFPYSKG-----RMKKEdyeqVEYALDLLQLQSIRHR-NIKTLSGGQRQRAYIA 147
Cdd:PRK10982 328 VTEERRSTGiYAYLDIGFNSLIsNIRNYKNKVGlldnsRMKSD----TQWVIDSMRVKTPGHRtQIGSLSGGNQQKVIIG 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 148 MTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAE 227
Cdd:PRK10982 404 RWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRILVMSNGLVAGIVDTKTTTQNE 482
|
...
gi 807234162 228 ILK 230
Cdd:PRK10982 483 ILR 485
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
16-213 |
3.87e-08 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 53.88 E-value: 3.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEG--------------------------------- 62
Cdd:PTZ00265 400 IYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDshnlkdinlkwwrskigvvsqdpllfsnsiknn 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 63 -----------KAVVDYKNDDLAKKLSILKQTNHT------EMNITVEQLVNFGRFPYSKGRMKKEDYEQVEYALDLL-- 123
Cdd:PTZ00265 480 ikyslyslkdlEALSNYYNEDGNDSQENKNKRNSCrakcagDLNDMSNTTDSNELIEMRKNYQTIKDSEVVDVSKKVLih 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 124 --------QLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHD 195
Cdd:PTZ00265 560 dfvsalpdKYETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHR 639
|
250
....*....|....*...
gi 807234162 196 INFAScYSDDIIALKNGE 213
Cdd:PTZ00265 640 LSTIR-YANTIFVLSNRE 656
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
105-226 |
4.25e-08 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 53.27 E-value: 4.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 105 KGRMKKEDYEQVEYALDLLQLQSIR-HRNIKT-----LSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTL 178
Cdd:PRK15093 122 KGRWWQRFGWRKRRAIELLHRVGIKdHKDAMRsfpyeLTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLL 201
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 807234162 179 RRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQA 226
Cdd:PRK15093 202 TRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTT 249
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
1-194 |
5.91e-08 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 53.21 E-value: 5.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKN-INVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvvdyknddlakKLSI 79
Cdd:TIGR00954 451 GIKFENIPLVTPNGDVLIEsLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKG-----------KLFY 519
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 80 LKQTNHTEMNITVEQLVnfgrFPYSKGRMKKEDY--EQVEYALDLLQLQSIRHRNI---------KTLSGGQRQRAYIAM 148
Cdd:TIGR00954 520 VPQRPYMTLGTLRDQII----YPDSSEDMKRRGLsdKDLEQILDNVQLTHILEREGgwsavqdwmDVLSGGEKQRIAMAR 595
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 807234162 149 TIAQDTDYILLDEPLNNLdmkhSVQIMQTLRRLCKDLNKTIVIVLH 194
Cdd:TIGR00954 596 LFYHKPQFAILDECTSAV----SVDVEGYMYRLCREFGITLFSVSH 637
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
15-168 |
8.38e-08 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 51.39 E-value: 8.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVvdyKNDDLAKKLSILKQTNHTEMNITVEQ 94
Cdd:PRK13543 25 PVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTA---TRGDRSRFMAYLGHLPGLKADLSTLE 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 95 LVNF--GRFPYSKGRMKKEdyeqveyALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDM 168
Cdd:PRK13543 102 NLHFlcGLHGRRAKQMPGS-------ALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
16-215 |
1.12e-07 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 52.42 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAV-SRLFEYEK---GTIKIEGKAVVDYKNDDLAKKLSILKQTNHTEmNIT 91
Cdd:TIGR00956 76 ILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIaSNTDGFHIgveGVITYDGITPEEIKKHYRGDVVYNAETDVHFP-HLT 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVNFG---RFPYSKGR-MKKEDYEQ--VEYALDLLQLQSIRHRN-----IKTLSGGQRQRAYIAMTIAQDTDYILLD 160
Cdd:TIGR00956 155 VGETLDFAarcKTPQNRPDgVSREEYAKhiADVYMATYGLSHTRNTKvgndfVRGVSGGERKRVSIAEASLGGAKIQCWD 234
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 807234162 161 EPLNNLDMKHSVQIMQTLrrlckdlnKTIVIVLHDINFASCYS---------DDIIALKNGEIV 215
Cdd:TIGR00956 235 NATRGLDSATALEFIRAL--------KTSANILDTTPLVAIYQcsqdayelfDKVIVLYEGYQI 290
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
20-223 |
1.58e-07 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 51.25 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 20 INVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILK---QTNHTEMN------- 89
Cdd:PRK15079 40 VTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVRSDIQmifQDPLASLNprmtige 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 90 ITVEQLVNFgrFPyskgRMKKEDY-EQV-EYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLD 167
Cdd:PRK15079 120 IIAEPLRTY--HP----KLSRQEVkDRVkAMMLKVGLLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALD 193
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 168 MKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV 223
Cdd:PRK15079 194 VSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEV 249
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
3-214 |
2.60e-07 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 49.35 E-value: 2.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLdkaiQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDlAKKLSIlkq 82
Cdd:cd03215 6 EVRGL----SVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRD-AIRAGI--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 83 tnhtemnitveqlvnfGRFPyskgrmkkEDYEQVeyalDLLQLQSIRhRNI---KTLSGGQRQRAYIAMTIAQDTDYILL 159
Cdd:cd03215 78 ----------------AYVP--------EDRKRE----GLVLDLSVA-ENIalsSLLSGGNQQKVVLARWLARDPRVLIL 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 160 DEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIV---LHDInFASCysDDIIALKNGEI 214
Cdd:cd03215 129 DEPTRGVDVGAKAEIYRLIREL-ADAGKAVLLIsseLDEL-LGLC--DRILVMYEGRI 182
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
17-223 |
6.31e-07 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 49.58 E-value: 6.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKND---DLAKKLSILKQTNHTEMN--IT 91
Cdd:PRK11308 31 LDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEaqkLLRQKIQIVFQNPYGSLNprKK 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQ------LVNfgrfpyskGRMKKEdyEQVEYALDLLQLQSIR----HRNIKTLSGGQRQRAYIAMTIAQDTDYILLDE 161
Cdd:PRK11308 111 VGQileeplLIN--------TSLSAA--ERREKALAMMAKVGLRpehyDRYPHMFSGGQRQRIAIARALMLDPDVVVADE 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 162 PLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNV 223
Cdd:PRK11308 181 PVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQI 242
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
5-195 |
8.50e-07 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 49.35 E-value: 8.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 5 KNLDKAI-QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLsavsrlfeyekgtiKI--------EGKAVvdyknddLAK 75
Cdd:PRK11819 10 NRVSKVVpPKKQILKDISLSFFPGAKIGVLGLNGAGKSTLL--------------RImagvdkefEGEAR-------PAP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 76 KLSI--LKQTNHTEMNITVEQLVNFG---------RFPYSKGRMKKEDYE-------------------------QVEYA 119
Cdd:PRK11819 69 GIKVgyLPQEPQLDPEKTVRENVEEGvaevkaaldRFNEIYAAYAEPDADfdalaaeqgelqeiidaadawdldsQLEIA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 807234162 120 LDLLQLQSiRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKhSVqimQTLRRLCKDLNKTIVIVLHD 195
Cdd:PRK11819 149 MDALRCPP-WDAKVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAE-SV---AWLEQFLHDYPGTVVAVTHD 219
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
15-214 |
1.45e-06 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 49.09 E-value: 1.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 15 PIL-KNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAvvdyknddlakKLSILKQTNHTEMNITVE 93
Cdd:PLN03073 522 PLLfKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAKV-----------RMAVFSQHHVDGLDLSSN 590
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 94 QLVNFGR----FPYSKGRMKKEDYEqveyALDLLQLQSIRhrnikTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMK 169
Cdd:PLN03073 591 PLLYMMRcfpgVPEQKLRAHLGSFG----VTGNLALQPMY-----TLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLD 661
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 807234162 170 HSVQIMQTLRRlckdLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:PLN03073 662 AVEALIQGLVL----FQGGVLMVSHDEHLISGSVDELWVVSEGKV 702
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
16-225 |
1.56e-06 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 49.07 E-value: 1.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEyekGTIKIEGKAVVD-YK-NDDLAKKLSILKQTNHTEMNI-TV 92
Cdd:PLN03140 180 ILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLD---PSLKVSGEITYNgYRlNEFVPRKTSAYISQNDVHVGVmTV 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 93 EQLVNF------------------------GRFPYSKGR--MKKEDYEQVE------YALDLLQLQSIRH-----RNIKT 135
Cdd:PLN03140 257 KETLDFsarcqgvgtrydllselarrekdaGIFPEAEVDlfMKATAMEGVKsslitdYTLKILGLDICKDtivgdEMIRG 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 136 LSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVL-------HDInfascySDDIIA 208
Cdd:PLN03140 337 ISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLMSLlqpapetFDL------FDDIIL 410
|
250
....*....|....*..
gi 807234162 209 LKNGEIVKADTKDNVIQ 225
Cdd:PLN03140 411 LSEGQIVYQGPRDHILE 427
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
120-225 |
2.05e-06 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 48.47 E-value: 2.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 120 LDLLQLQsirhRNIKTLSGGQRQRAYIAMTIAQDTDYIL--LDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHD-- 195
Cdd:TIGR00630 477 LDYLSLS----RAAGTLSGGEAQRIRLATQIGSGLTGVLyvLDEPSIGLHQRDNRRLINTLKRL-RDLGNTLIVVEHDed 551
|
90 100 110
....*....|....*....|....*....|....*..
gi 807234162 196 -INFAscysDDIIAL------KNGEIVKADTKDNVIQ 225
Cdd:TIGR00630 552 tIRAA----DYVIDIgpgageHGGEVVASGTPEEILA 584
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
117-226 |
2.33e-06 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 47.98 E-value: 2.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 117 EYALDLLQLQSIR-HRNIKT-----LSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIV 190
Cdd:COG4170 134 KRAIELLHRVGIKdHKDIMNsypheLTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSIL 213
|
90 100 110
....*....|....*....|....*....|....*.
gi 807234162 191 IVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQA 226
Cdd:COG4170 214 LISHDLESISQWADTITVLYCGQTVESGPTEQILKS 249
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1-198 |
2.65e-06 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 47.96 E-value: 2.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEgkavvdyKNDDLAKklsiL 80
Cdd:PRK15064 1 MLSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLD-------PNERLGK----L 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 81 KQTN---------------HTEM-NITVEQlvnfGRFpYSKGRMKKEDYEQV--------EY--------ALDLLQLQSI 128
Cdd:PRK15064 70 RQDQfafeeftvldtvimgHTELwEVKQER----DRI-YALPEMSEEDGMKVadlevkfaEMdgytaearAGELLLGVGI 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 129 ---RHRN-IKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDmkhsvqiMQTLRRLCKDLNK---TIVIVLHDINF 198
Cdd:PRK15064 145 peeQHYGlMSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLD-------INTIRWLEDVLNErnsTMIIISHDRHF 214
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
17-219 |
3.36e-06 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 47.22 E-value: 3.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLS-----AVSRLFEYEKGTIK----IEGKAVVD-------------------- 67
Cdd:cd03271 11 LKNIDVDIPLGVLTCVTGVSGSGKSSLINdtlypALARRLHLKKEQPGnhdrIEGLEHIDkvividqspigrtprsnpat 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 68 --------------------YKNDDLA---KKLSIlkqtnHTEMNITVEQLVNFgrFpyskgrmkkEDYEQVEYALDLLQ 124
Cdd:cd03271 91 ytgvfdeirelfcevckgkrYNRETLEvryKGKSI-----ADVLDMTVEEALEF--F---------ENIPKIARKLQTLC 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 125 ---LQSIR-HRNIKTLSGGQRQRAYIAMTIAQ----DTDYILlDEPLNNL---DMKHSVQIMQTLRrlckDLNKTIVIVL 193
Cdd:cd03271 155 dvgLGYIKlGQPATTLSGGEAQRIKLAKELSKrstgKTLYIL-DEPTTGLhfhDVKKLLEVLQRLV----DKGNTVVVIE 229
|
250 260 270
....*....|....*....|....*....|..
gi 807234162 194 HDINFASCySDDIIAL------KNGEIVKADT 219
Cdd:cd03271 230 HNLDVIKC-ADWIIDLgpeggdGGGQVVASGT 260
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
29-198 |
3.68e-06 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 46.45 E-value: 3.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 29 LTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKavvdyKNDDLAKKLSILKQtnhtemnITVEQLVNFGRfPYSKGRm 108
Cdd:cd03240 24 LTLIVGQNGAGKTTIIEALKYALTGELPPNSKGGA-----HDPKLIREGEVRAQ-------VKLAFENANGK-KYTITR- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 109 kkeDYEQVEYALDLLQ--LQSIRHRNIKTLSGGQRQ------RAYIAMTIAQDTDYILLDEPLNNLDMKH-SVQIMQTLR 179
Cdd:cd03240 90 ---SLAILENVIFCHQgeSNWPLLDMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENiEESLAEIIE 166
|
170
....*....|....*....
gi 807234162 180 RLCKDLNKTIVIVLHDINF 198
Cdd:cd03240 167 ERKSQKNFQLIVITHDEEL 185
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1-232 |
4.68e-06 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 46.71 E-value: 4.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 1 MIEIKNLDKAI---------QNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVV--DYK 69
Cdd:PRK15112 4 LLEVRNLSKTFryrtgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfgDYS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 70 NDdlAKKLSILKQTNHTEMNIT--VEQLVNFG-RFPYSKGRMKKEdyEQVEYALDLLQLQSiRHRNI--KTLSGGQRQRA 144
Cdd:PRK15112 84 YR--SQRIRMIFQDPSTSLNPRqrISQILDFPlRLNTDLEPEQRE--KQIIETLRQVGLLP-DHASYypHMLAPGQKQRL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 145 YIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:PRK15112 159 GLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVL 238
|
250
....*....|.
gi 807234162 225 QA---EILKQL 232
Cdd:PRK15112 239 ASplhELTKRL 249
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
16-196 |
5.49e-06 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 47.21 E-value: 5.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEkGTIKIEGkavVDYKnddlakklSILKQTNHTEMNITVEQL 95
Cdd:TIGR01271 1234 VLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDG---VSWN--------SVTLQTWRKAFGVIPQKV 1301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 96 VNF-GRFpyskgRMKKEDYEQ------------------VEYALDLLQLQSIRHRNIktLSGGQRQRAYIAMTIAQDTDY 156
Cdd:TIGR01271 1302 FIFsGTF-----RKNLDPYEQwsdeeiwkvaeevglksvIEQFPDKLDFVLVDGGYV--LSNGHKQLMCLARSILSKAKI 1374
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 807234162 157 ILLDEPLNNLDmkhsVQIMQTLRRLCKDL--NKTIVIVLHDI 196
Cdd:TIGR01271 1375 LLLDEPSAHLD----PVTLQIIRKTLKQSfsNCTVILSEHRV 1412
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
2-50 |
5.69e-06 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 46.85 E-value: 5.69e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 807234162 2 IEIKNLdKAIqnkpilKNINVDIqkGRLTSLIGPNGAGKSTLLSAVSRL 50
Cdd:COG4637 5 IRIKNF-KSL------RDLELPL--GPLTVLIGANGSGKSNLLDALRFL 44
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
13-214 |
6.40e-06 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 47.09 E-value: 6.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIkiegkavvdykndDLAK--KLSILKQTNHTEMNI 90
Cdd:PRK10636 324 DRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEI-------------GLAKgiKLGYFAQHQLEFLRA 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 TVEQLVNFGRFPYSKGRMKKEDYEQvEYALDLLQLQSIRHRniktLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMkh 170
Cdd:PRK10636 391 DESPLQHLARLAPQELEQKLRDYLG-GFGFQGDKVTEETRR----FSGGEKARLVLALIVWQRPNLLLLDEPTNHLDL-- 463
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 807234162 171 svQIMQTLRRLCKDLNKTIVIVLHDINFASCYSDDIIALKNGEI 214
Cdd:PRK10636 464 --DMRQALTEALIDFEGALVVVSHDRHLLRSTTDDLYLVHDGKV 505
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
2-196 |
6.41e-06 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 45.77 E-value: 6.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLdkaiqnKPILKNINVDIQKGrLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSIlk 81
Cdd:COG0419 5 LRLENF------RSYRDTETIDFDDG-LNLIVGPNGAGKSTILEAIRYALYGKARSRSKLRSDLINVGSEEASVELEF-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNHTEMNITVEQLvNFGRFPYSKGRMKKE---------DYEQVEYALDLLQ------------LQSIRHR--------- 131
Cdd:COG0419 76 EHGGKRYRIERRQG-EFAEFLEAKPSERKEalkrllgleIYEELKERLKELEealesaleelaeLQKLKQEilaqlsgld 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 807234162 132 NIKTLSGGQRQRAYIAMTIAqdtdyILLDepLNNLDMKHSVQIMQTLRRLckdlnktiVIVLHDI 196
Cdd:COG0419 155 PIETLSGGERLRLALADLLS-----LILD--FGSLDEERLERLLDALEEL--------AIITHVI 204
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
2-167 |
1.02e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 46.16 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 2 IEIKNLDKAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVS-----------RLFEYEKGTikieGKAVVDYKn 70
Cdd:PRK10938 261 IVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITgdhpqgysndlTLFGRRRGS----GETIWDIK- 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 71 ddlaKKLSILKQTNHTE--MNITVEQLVNFGRFPySKGRmkkedYEQVEYA--------LDLLQL-QSIRHRNIKTLSGG 139
Cdd:PRK10938 336 ----KHIGYVSSSLHLDyrVSTSVRNVILSGFFD-SIGI-----YQAVSDRqqklaqqwLDILGIdKRTADAPFHSLSWG 405
|
170 180
....*....|....*....|....*...
gi 807234162 140 QRQRAYIAMTIAQDTDYILLDEPLNNLD 167
Cdd:PRK10938 406 QQRLALIVRALVKHPTLLILDEPLQGLD 433
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
17-48 |
1.16e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 46.27 E-value: 1.16e-05
10 20 30
....*....|....*....|....*....|..
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVS 48
Cdd:NF033858 17 LDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIA 48
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
16-196 |
1.65e-05 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 45.23 E-value: 1.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFeYEKGTIKIEGKAVVDYKNDDLAKKLSILKQ-----TNHTEMNI 90
Cdd:cd03289 19 VLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLL-NTEGDIQIDGVSWNSVPLQKWRKAFGVIPQkvfifSGTFRKNL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 91 TveqlvnfgrfPYskGRMKKEDYEQV--EYALDLL------QLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEP 162
Cdd:cd03289 98 D----------PY--GKWSDEEIWKVaeEVGLKSVieqfpgQLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEP 165
|
170 180 190
....*....|....*....|....*....|....
gi 807234162 163 LNNLDMKHSVQIMQTLRRLCKDLnkTIVIVLHDI 196
Cdd:cd03289 166 SAHLDPITYQVIRKTLKQAFADC--TVILSEHRI 197
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
16-207 |
1.77e-05 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 45.55 E-value: 1.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVsrlfeyeKGTIKIEGKAVVDYKNDDLAkklSILKQTNHTEMNiTVEQL 95
Cdd:PRK10636 16 LLDNATATINPGQKVGLVGKNGCGKSTLLALL-------KNEISADGGSYTFPGNWQLA---WVNQETPALPQP-ALEYV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 96 VNFGRfpyskgrmkkeDYEQVEYAL-------------------DLLQLQSIRHRN-----------------IKTLSGG 139
Cdd:PRK10636 85 IDGDR-----------EYRQLEAQLhdanerndghaiatihgklDAIDAWTIRSRAasllhglgfsneqlerpVSDFSGG 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 140 QRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQimqtLRRLCKDLNKTIVIVLHDINFASCYSDDII 207
Cdd:PRK10636 154 WRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIW----LEKWLKSYQGTLILISHDRDFLDPIVDKII 217
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
21-232 |
2.44e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 45.01 E-value: 2.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 21 NVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQTNHTEMNITVEQlvNFGR 100
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLSPGED--DTGR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 101 FPYSKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDmkhsVQIMQTLRR 180
Cdd:PRK10938 101 TTAEIIQDEVKDPARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLD----VASRQQLAE 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 181 LCKDLNK---TIVIVL---HDI-NFAscysDDIIALKNGEIVKADTKDNVIQAEILKQL 232
Cdd:PRK10938 177 LLASLHQsgiTLVLVLnrfDEIpDFV----QFAGVLADCTLAETGEREEILQQALVAQL 231
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
3-215 |
2.67e-05 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 45.02 E-value: 2.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 3 EIKNLD-KAIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDyknddlakkLSILK 81
Cdd:COG3845 259 EVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITG---------LSPRE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 82 QTNH---------------TEMNITvEQLV--NFGRFPYSKGRMkkEDYEQV-EYALDLLQLQSIRHRNI----KTLSGG 139
Cdd:COG3845 330 RRRLgvayipedrlgrglvPDMSVA-ENLIlgRYRRPPFSRGGF--LDRKAIrAFAEELIEEFDVRTPGPdtpaRSLSGG 406
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 807234162 140 QRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRRLCkDLNKTIVIVLHDIN--FAscYSDDIIALKNGEIV 215
Cdd:COG3845 407 NQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELR-DAGAAVLLISEDLDeiLA--LSDRIAVMYEGRIV 481
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
34-195 |
6.23e-05 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 43.03 E-value: 6.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 34 GPNGAGKSTLLSAVS-RLFeyekgtikieGKAvvdyKNDDLAKKLSILKQTNHTEMNITVEQLVNFGRfpYSKGRMKKED 112
Cdd:cd03279 35 GPTGAGKSTILDAITyALY----------GKT----PRYGRQENLRSVFAPGEDTAEVSFTFQLGGKK--YRVERSRGLD 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 113 YEQVEYALDLLQLQSIR--HRNIKTLSGGQRQRAYIAMTIA-----QDT-----DYILLDEPLNNLDMKHSVQIMQTLRR 180
Cdd:cd03279 99 YDQFTRIVLLPQGEFDRflARPVSTLSGGETFLASLSLALAlsevlQNRggarlEALFIDEGFGTLDPEALEAVATALEL 178
|
170
....*....|....*
gi 807234162 181 LcKDLNKTIVIVLHD 195
Cdd:cd03279 179 I-RTENRMVGVISHV 192
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
16-212 |
6.42e-05 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 44.00 E-value: 6.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 16 ILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKQtNHTEMNITVEQL 95
Cdd:PTZ00243 1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRELRRQFSMIPQ-DPVLFDGTVRQN 1403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 96 VNfgrfPYSKGrmkkeDYEQVEYALDLLQLqsiRHR--------NIKTLSGGQR----QRAYIAMTIA---QDTDYILLD 160
Cdd:PTZ00243 1404 VD----PFLEA-----SSAEVWAALELVGL---RERvasesegiDSRVLEGGSNysvgQRQLMCMARAllkKGSGFILMD 1471
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 807234162 161 EPLNNLDMKHSVQIMQTLRRLCKdlNKTIVIVLHDINFASCYsDDIIALKNG 212
Cdd:PTZ00243 1472 EATANIDPALDRQIQATVMSAFS--AYTVITIAHRLHTVAQY-DKIIVMDHG 1520
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
17-224 |
8.17e-05 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 42.88 E-value: 8.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDLAKKLSILKqtnhtemNITVEQLV 96
Cdd:PRK13546 40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIE-------NIEFKMLC 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 97 nfgrFPYSKGRMKKEDYEQVEYAldllQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQ 176
Cdd:PRK13546 113 ----MGFKRKEIKAMTPKIIEFS----ELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLD 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 807234162 177 TLRRLcKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVI 224
Cdd:PRK13546 185 KIYEF-KEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVL 231
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
20-230 |
8.33e-05 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 43.36 E-value: 8.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 20 INVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVV-----------------DYKNDDLAKKLSIlkQ 82
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDirsprdairagimlcpeDRKAEGIIPVHSV--A 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 83 TNhteMNITveqlvnfGRFPYSKGRMKKEDYEQVEYALDLLQLQSIRHRN----IKTLSGGQRQRAYIAMTIAQDTDYIL 158
Cdd:PRK11288 350 DN---INIS-------ARRHHLRAGCLINNRWEAENADRFIRSLNIKTPSreqlIMNLSGGNQQKAILGRWLSEDMKVIL 419
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 807234162 159 LDEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILK 230
Cdd:PRK11288 420 LDEPTRGIDVGAKHEIYNVIYELAAQ-GVAVLFVSSDLPEVLGVADRIVVMREGRIAGELAREQATERQALS 490
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
17-220 |
1.02e-04 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 43.07 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 17 LKNINVDIQKGrLTSLIGPNGAGKSTLLSAVSRLF-----------------EYEKGTIKIE-------GKAVVDYKNDD 72
Cdd:COG3593 14 IKDLSIELSDD-LTVLVGENNSGKSSILEALRLLLgpsssrkfdeedfylgdDPDLPEIEIEltfgsllSRLLRLLLKEE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 73 LAKKLSILKQTNHTEMNITVEQLVNF------GRFPYSKGRMKKEDYEQVEYALDL-LQLQSIRHRNIKTLSGGQRQRAY 145
Cdd:COG3593 93 DKEELEEALEELNEELKEALKALNELlseylkELLDGLDLELELSLDELEDLLKSLsLRIEDGKELPLDRLGSGFQRLIL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 146 IAMTIA------QDTDYILL-DEPLNNLDMKHSVQIMQTLRRLCKDlNKTIVIVLHDINFASCYS-DDIIALKNGEIVKA 217
Cdd:COG3593 173 LALLSAlaelkrAPANPILLiEEPEAHLHPQAQRRLLKLLKELSEK-PNQVIITTHSPHLLSEVPlENIRRLRRDSGGTT 251
|
...
gi 807234162 218 DTK 220
Cdd:COG3593 252 STK 254
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
22-51 |
1.03e-04 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 39.51 E-value: 1.03e-04
10 20 30
....*....|....*....|....*....|
gi 807234162 22 VDIQKGRLTSLIGPNGAGKSTLLSAVSRLF 51
Cdd:pfam13555 17 IPIDPRGNTLLTGPSGSGKSTLLDAIQTLL 46
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
2-51 |
1.12e-04 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 42.68 E-value: 1.12e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 807234162 2 IEIKNLdkaiqnKPIlKNINVDI-QKGRLTSLIGPNGAGKSTLLSAVSRLF 51
Cdd:COG3950 6 LTIENF------RGF-EDLEIDFdNPPRLTVLVGENGSGKTTLLEAIALAL 49
|
|
| RloC |
COG4694 |
Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis]; |
3-80 |
2.54e-04 |
|
Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 443729 [Multi-domain] Cd Length: 692 Bit Score: 42.03 E-value: 2.54e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 807234162 3 EIKNLDKaIQNKPILKNINVDIQKGRLTSLIGPNGAGKSTLlsavSRLFEY-EKGTIKIEGKAVVDYKNDDLAKKLSIL 80
Cdd:COG4694 1 MITKIKK-LKNVGAFKDFGWLAFFKKLNLIYGENGSGKSTL----SRILRSlELGDTSSEVIAEFEIEAGGSAPNPSVR 74
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
29-257 |
2.67e-04 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 41.61 E-value: 2.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 29 LTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDYKNDDL--------AKKLSILKQTNHTEMNITVEQLVNFGR 100
Cdd:pfam13304 1 INVLIGPNGSGKSNLLEALRFLADFDALVIGLTDERSRNGGIGGIpsllngidPKEPIEFEISEFLEDGVRYRYGLDLER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 101 FPYSkgrMKKEDYEQVEYALDLLQLQSIRhRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIMQTLRR 180
Cdd:pfam13304 81 EDVE---EKLSSKPTLLEKRLLLREDSEE-REPKFPPEAEELRLGLDVEERIELSLSELSDLISGLLLLSIISPLSFLLL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 807234162 181 LCKDLNKTIVIVLHDINFASCYSDDIIALKNGEIVKADTKDNVIQAEILKQLYEMDVHIEEIRGQRICLYYDEDTFD 257
Cdd:pfam13304 157 LDEGLLLEDWAVLDLAADLALFPDLKELLQRLVRGLKLADLNLSDLGEGIEKSLLVDDRLRERGLILLENGGGGELP 233
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
131-207 |
2.72e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.12 E-value: 2.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 131 RNIKTLSGGQRQRAYIAMTIAQDTDYI--LLDEPLNNLDMKHSVQIMQTLRRLcKDLNKTIVIVLHD---INFAscysDD 205
Cdd:PRK00635 472 RALATLSGGEQERTALAKHLGAELIGItyILDEPSIGLHPQDTHKLINVIKKL-RDQGNTVLLVEHDeqmISLA----DR 546
|
..
gi 807234162 206 II 207
Cdd:PRK00635 547 II 548
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
17-43 |
3.63e-04 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 41.55 E-value: 3.63e-04
10 20
....*....|....*....|....*..
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTL 43
Cdd:COG0178 16 LKNIDVDIPRNKLVVITGLSGSGKSSL 42
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
111-224 |
4.30e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 41.54 E-value: 4.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 111 EDYEQVEYALDLLQ---LQSIR-HRNIKTLSGGQRQRAYIAMTIAQ----DTDYILlDEPLNNLDMKHSVQIMQTLRRLc 182
Cdd:TIGR00630 801 EAVPSISRKLQTLCdvgLGYIRlGQPATTLSGGEAQRIKLAKELSKrstgRTLYIL-DEPTTGLHFDDIKKLLEVLQRL- 878
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 807234162 183 KDLNKTIVIVLHDINFASCySDDIIAL------KNGEIVKADTKDNVI 224
Cdd:TIGR00630 879 VDKGNTVVVIEHNLDVIKT-ADYIIDLgpeggdGGGTVVASGTPEEVA 925
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
13-196 |
4.46e-04 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 41.54 E-value: 4.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 13 NKPILKNINVDIQKGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIEGKAVVDyKNDDLAKKLSILKQTNHTEMNIT- 91
Cdd:TIGR01257 1951 SSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILT-NISDVHQNMGYCPQFDAIDDLLTg 2029
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 92 VEQLVNFGRFpysKGRMKKEDYEQVEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHS 171
Cdd:TIGR01257 2030 REHLYLYARL---RGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQAR 2106
|
170 180
....*....|....*....|....*
gi 807234162 172 VQIMQTLRRLCKDlNKTIVIVLHDI 196
Cdd:TIGR01257 2107 RMLWNTIVSIIRE-GRAVVLTSHSM 2130
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
17-44 |
1.01e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 40.38 E-value: 1.01e-03
10 20
....*....|....*....|....*...
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTLL 44
Cdd:TIGR00630 624 LKNITVSIPLGLFTCITGVSGSGKSTLI 651
|
|
| COG4938 |
COG4938 |
Predicted ATPase [General function prediction only]; |
2-47 |
1.28e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443965 [Multi-domain] Cd Length: 277 Bit Score: 39.18 E-value: 1.28e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 807234162 2 IEIKNLdkaiqnKPIlKNINVDIqkGRLTSLIGPNGAGKSTLLSAV 47
Cdd:COG4938 4 ISIKNF------GPF-KEAELEL--KPLTLLIGPNGSGKSTLIQAL 40
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
1-43 |
2.82e-03 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 38.85 E-value: 2.82e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 807234162 1 MIEIKNldkAIQNKpiLKNINVDIQKGRLTSLIGPNGAGKSTL 43
Cdd:COG0178 610 FLTIKG---ARENN--LKNVDVEIPLGVLTCVTGVSGSGKSTL 647
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
1-44 |
2.89e-03 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 38.90 E-value: 2.89e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 807234162 1 MIEIKNldkAIQNKpiLKNINVDIQKGRLTSLIGPNGAGKSTLL 44
Cdd:PRK00349 614 FLKLKG---ARENN--LKNVDVEIPLGKFTCVTGVSGSGKSTLI 652
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
26-198 |
3.39e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 36.97 E-value: 3.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 26 KGRLTSLIGPNGAGKSTLLSAVSRLFEYEKGTIKIegkavvdyknddlakklsilkqtnhtemnITVEQLvnfgrfpysk 105
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----------------------------IDGEDI---------- 41
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 807234162 106 grmkkedyeqvEYALDLLQLQSIRHRNIKTLSGGQRQRAYIAMTIAQDTDYILLDEPLNNLDMKHSVQIM-----QTLRR 180
Cdd:smart00382 42 -----------LEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLlleelRLLLL 110
|
170
....*....|....*...
gi 807234162 181 LCKDLNKTIVIVLHDINF 198
Cdd:smart00382 111 LKSEKNLTVILTTNDEKD 128
|
|
| ABC_SMC1_euk |
cd03275 |
ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of ... |
28-48 |
4.30e-03 |
|
ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213242 [Multi-domain] Cd Length: 247 Bit Score: 37.55 E-value: 4.30e-03
|
| EF-G_bact |
cd04170 |
Elongation factor G (EF-G) family; Translocation is mediated by EF-G (also called translocase). ... |
31-79 |
4.75e-03 |
|
Elongation factor G (EF-G) family; Translocation is mediated by EF-G (also called translocase). The structure of EF-G closely resembles that of the complex between EF-Tu and tRNA. This is an example of molecular mimicry; a protein domain evolved so that it mimics the shape of a tRNA molecule. EF-G in the GTP form binds to the ribosome, primarily through the interaction of its EF-Tu-like domain with the 50S subunit. The binding of EF-G to the ribosome in this manner stimulates the GTPase activity of EF-G. On GTP hydrolysis, EF-G undergoes a conformational change that forces its arm deeper into the A site on the 30S subunit. To accommodate this domain, the peptidyl-tRNA in the A site moves to the P site, carrying the mRNA and the deacylated tRNA with it. The ribosome may be prepared for these rearrangements by the initial binding of EF-G as well. The dissociation of EF-G leaves the ribosome ready to accept the next aminoacyl-tRNA into the A site. This group contains only bacterial members.
Pssm-ID: 206733 [Multi-domain] Cd Length: 268 Bit Score: 37.57 E-value: 4.75e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 807234162 31 SLIGPNGAGKSTLLSAVSrlfeYEKGTIK----IE-GKAVVDYKNDDLAKKLSI 79
Cdd:cd04170 3 ALVGHSGSGKTTLAEALL----YATGAIDrlgrVEdGNTVSDYDPEEKKRKMSI 52
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
17-43 |
9.75e-03 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 36.97 E-value: 9.75e-03
10 20
....*....|....*....|....*..
gi 807234162 17 LKNINVDIQKGRLTSLIGPNGAGKSTL 43
Cdd:PRK00349 16 LKNIDLDIPRDKLVVFTGLSGSGKSSL 42
|
|
| |
