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Conserved domains on  [gi|743680319|gb|AJC22453|]
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transcriptional regulator [Pandoraea pulmonicola]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 11483109)

helix-turn-helix transcriptional regulator similar to Bradyrhizobium diazoefficiens anaerobic benzoate catabolism transcriptional regulator that controls inducible expression of the bzd catabolic operon that is involved in the anaerobic catabolism of benzoate; contains a C-terminal shikimate kinase-like domain which may bind benzoyl-CoA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 6-310 1.64e-108

anaerobic benzoate catabolism transcriptional regulator; Reviewed


:

Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 317.67  E-value: 1.64e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319   6 ADSLPPDRLSPTNAGDTGDAIAPQLALLARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALN 85
Cdd:PRK08154   2 ADADAGPTADATAMTGAAAEEAPFLAALGERVRTLRARRGMSRKVLAQASGVSERYLAQLESGQGNVSILLLRRVARALG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  86 VGVETLVAERMAYDGDLLILVEYLRQQPAEVLSRLRRQIV-VPAAAEARGKGRRIALIGLRGAGKSTLGPRLAQAFGAPF 164
Cdd:PRK08154  82 CSLADLLGDVDTSSPDWLLIRELLEQASPAQLARVRDALSgMLGAGRRAARRRRIALIGLRGAGKSTLGRMLAARLGVPF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 165 VELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHDNVVLATGGGIVSEAQTYERVLRTFRTVWLRARPDVHF 244
Cdd:PRK08154 162 VELNREIEREAGLSVSEIFALYGQEGYRRLERRALERLIAEHEEMVLATGGGIVSEPATFDLLLSHCYTVWLKASPEEHM 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 743680319 245 QRVMQQNDARIAteALRNEALEHIHRMLDAREALYQLADVTLDTSDITPDAALAALQDTLSPARAA 310
Cdd:PRK08154 242 ARVRAQGDLRPM--ADNREAMEDLRRILASREPLYARADAVVDTSGLTVAQSLARLRELVRPALGL 305
 
Name Accession Description Interval E-value
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 6-310 1.64e-108

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 317.67  E-value: 1.64e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319   6 ADSLPPDRLSPTNAGDTGDAIAPQLALLARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALN 85
Cdd:PRK08154   2 ADADAGPTADATAMTGAAAEEAPFLAALGERVRTLRARRGMSRKVLAQASGVSERYLAQLESGQGNVSILLLRRVARALG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  86 VGVETLVAERMAYDGDLLILVEYLRQQPAEVLSRLRRQIV-VPAAAEARGKGRRIALIGLRGAGKSTLGPRLAQAFGAPF 164
Cdd:PRK08154  82 CSLADLLGDVDTSSPDWLLIRELLEQASPAQLARVRDALSgMLGAGRRAARRRRIALIGLRGAGKSTLGRMLAARLGVPF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 165 VELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHDNVVLATGGGIVSEAQTYERVLRTFRTVWLRARPDVHF 244
Cdd:PRK08154 162 VELNREIEREAGLSVSEIFALYGQEGYRRLERRALERLIAEHEEMVLATGGGIVSEPATFDLLLSHCYTVWLKASPEEHM 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 743680319 245 QRVMQQNDARIAteALRNEALEHIHRMLDAREALYQLADVTLDTSDITPDAALAALQDTLSPARAA 310
Cdd:PRK08154 242 ARVRAQGDLRPM--ADNREAMEDLRRILASREPLYARADAVVDTSGLTVAQSLARLRELVRPALGL 305
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 138-295 7.00e-49

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 160.03  E-value: 7.00e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 138 RIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQcIERIIAEHDNVVLATGGGI 217
Cdd:cd00464    1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELERE-VLLLLLTKENAVIATGGGA 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 743680319 218 VSEAQTYERVLRTFRTVWLRARPDVHFQRVMQQNDaRIateALRNEALEHIHRMLDAREALY-QLADVTLDTSDITPDA 295
Cdd:cd00464   80 VLREENRRLLLENGIVVWLDASPEELLERLARDKT-RP---LLQDEDPERLRELLEEREPLYrEVADLTIDTDELSPEE 154
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 139-305 3.23e-47

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 156.06  E-value: 3.23e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 139 IALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHdNVVLATGGGIV 218
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEEE-NAVIATGGGAV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 219 SEAQTYERVLRTFRTVWLRARPDVHFQRVmQQNDAR--IATEalrnEALEHIHRMLDAREALY-QLADVTLDTSDITPDA 295
Cdd:COG0703   80 LSPENRELLKEHGTVVYLDASPETLLERL-RRDDNRplLQGE----DPRERLEELLAEREPLYrEVADITVDTDGRSPEE 154

                        170
                 ....*....|
gi 743680319 296 ALAALQDTLS 305
Cdd:COG0703  155 VVDEILEALE 164
SKI pfam01202
Shikimate kinase;
145-299 1.16e-30

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 113.06  E-value: 1.16e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  145 RGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHdNVVLATGGGIVSEAQTY 224
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAEH-GLVIATGGGAVLSEENR 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 743680319  225 ERVLRTFRTVWLRARPDVHFQRVMQQNDARIATEALRNEALEHIhrMLDAREALYQLADVTLDTSDITPDAALAA 299
Cdd:pfam01202  80 DLLKERGIVIYLDAPLEVLLERLKRDKTRPLLQNKDPEEELLEL--LFEERDPLYEEAADIVIDTDESSPEEVAT 152
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
36-91 6.34e-10

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 54.06  E-value: 6.34e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 743680319    36 RVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETL 91
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
 
Name Accession Description Interval E-value
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 6-310 1.64e-108

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 317.67  E-value: 1.64e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319   6 ADSLPPDRLSPTNAGDTGDAIAPQLALLARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALN 85
Cdd:PRK08154   2 ADADAGPTADATAMTGAAAEEAPFLAALGERVRTLRARRGMSRKVLAQASGVSERYLAQLESGQGNVSILLLRRVARALG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  86 VGVETLVAERMAYDGDLLILVEYLRQQPAEVLSRLRRQIV-VPAAAEARGKGRRIALIGLRGAGKSTLGPRLAQAFGAPF 164
Cdd:PRK08154  82 CSLADLLGDVDTSSPDWLLIRELLEQASPAQLARVRDALSgMLGAGRRAARRRRIALIGLRGAGKSTLGRMLAARLGVPF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 165 VELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHDNVVLATGGGIVSEAQTYERVLRTFRTVWLRARPDVHF 244
Cdd:PRK08154 162 VELNREIEREAGLSVSEIFALYGQEGYRRLERRALERLIAEHEEMVLATGGGIVSEPATFDLLLSHCYTVWLKASPEEHM 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 743680319 245 QRVMQQNDARIAteALRNEALEHIHRMLDAREALYQLADVTLDTSDITPDAALAALQDTLSPARAA 310
Cdd:PRK08154 242 ARVRAQGDLRPM--ADNREAMEDLRRILASREPLYARADAVVDTSGLTVAQSLARLRELVRPALGL 305
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 138-295 7.00e-49

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 160.03  E-value: 7.00e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 138 RIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQcIERIIAEHDNVVLATGGGI 217
Cdd:cd00464    1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELERE-VLLLLLTKENAVIATGGGA 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 743680319 218 VSEAQTYERVLRTFRTVWLRARPDVHFQRVMQQNDaRIateALRNEALEHIHRMLDAREALY-QLADVTLDTSDITPDA 295
Cdd:cd00464   80 VLREENRRLLLENGIVVWLDASPEELLERLARDKT-RP---LLQDEDPERLRELLEEREPLYrEVADLTIDTDELSPEE 154
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 139-305 3.23e-47

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 156.06  E-value: 3.23e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 139 IALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHdNVVLATGGGIV 218
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEEE-NAVIATGGGAV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 219 SEAQTYERVLRTFRTVWLRARPDVHFQRVmQQNDAR--IATEalrnEALEHIHRMLDAREALY-QLADVTLDTSDITPDA 295
Cdd:COG0703   80 LSPENRELLKEHGTVVYLDASPETLLERL-RRDDNRplLQGE----DPRERLEELLAEREPLYrEVADITVDTDGRSPEE 154

                        170
                 ....*....|
gi 743680319 296 ALAALQDTLS 305
Cdd:COG0703  155 VVDEILEALE 164
aroK PRK00131
shikimate kinase; Reviewed
 135-295 8.25e-33

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 119.14  E-value: 8.25e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 135 KGRRIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHdNVVLATG 214
Cdd:PRK00131   3 KGPNIVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLARH-NLVISTG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 215 GGIVSEAQTYERVLRTFRTVWLRARPDVHFQRV--------MQQNDARiatealrnealEHIHRMLDAREALY-QLADVT 285
Cdd:PRK00131  82 GGAVLREENRALLRERGTVVYLDASFEELLRRLrrdrnrplLQTNDPK-----------EKLRDLYEERDPLYeEVADIT 150

                        170
                 ....*....|
gi 743680319 286 LDTSDITPDA 295
Cdd:PRK00131 151 VETDGRSPEE 160
SKI pfam01202
Shikimate kinase;
145-299 1.16e-30

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 113.06  E-value: 1.16e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  145 RGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHdNVVLATGGGIVSEAQTY 224
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAEH-GLVIATGGGAVLSEENR 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 743680319  225 ERVLRTFRTVWLRARPDVHFQRVMQQNDARIATEALRNEALEHIhrMLDAREALYQLADVTLDTSDITPDAALAA 299
Cdd:pfam01202  80 DLLKERGIVIYLDAPLEVLLERLKRDKTRPLLQNKDPEEELLEL--LFEERDPLYEEAADIVIDTDESSPEEVAT 152
PRK13947 PRK13947
shikimate kinase; Provisional
 137-300 8.60e-27

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 103.25  E-value: 8.60e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 137 RRIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERiIAEHDNVVLATGGG 216
Cdd:PRK13947   2 KNIVLIGFMGTGKTTVGKRVATTLSFGFIDTDKEIEKMTGMTVAEIFEKDGEVRFRSEEKLLVKK-LARLKNLVIATGGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 217 IVSEAQTYERVLRTFRTVWLRARPDVHFQRVMQQNDARIateALRNEALEHIHRMLDAREALYQLADVTLDTSDITPDAA 296
Cdd:PRK13947  81 VVLNPENVVQLRKNGVVICLKARPEVILRRVGKKKSRPL---LMVGDPEERIKELLKEREPFYDFADYTIDTGDMTIDEV 157


                 ....
gi 743680319 297 LAAL 300
Cdd:PRK13947 158 AEEI 161
PRK13946 PRK13946
shikimate kinase; Provisional
 128-310 2.27e-23

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 94.61  E-value: 2.27e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 128 AAAEARGKgRRIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEhD 207
Cdd:PRK13946   3 RARAALGK-RTVVLVGLMGAGKSTVGRRLATMLGLPFLDADTEIERAARMTIAEIFAAYGEPEFRDLERRVIARLLKG-G 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 208 NVVLATGGGIVSEAQTYERVLRTFRTVWLRARPDVHFQRVmQQNDARiatEALRNE-ALEHIHRMLDAREALYQLADVTL 286
Cdd:PRK13946  81 PLVLATGGGAFMNEETRAAIAEKGISVWLKADLDVLWERV-SRRDTR---PLLRTAdPKETLARLMEERYPVYAEADLTV 156

                        170       180
                 ....*....|....*....|....*...
gi 743680319 287 DTSD----ITPDAALAALQDTLSPARAA 310
Cdd:PRK13946 157 ASRDvpkeVMADEVIEALAAYLEKEEAA 184
PRK13951 PRK13951
bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;
138-292 1.49e-21

bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;


Pssm-ID: 172457 [Multi-domain]  Cd Length: 488  Bit Score: 94.59  E-value: 1.49e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 138 RIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERiIAEHDNVVLATGGGI 217
Cdd:PRK13951   2 RIFLVGMMGSGKSTIGKRVSEVLDLQFIDMDEEIERREGRSVRRIFEEDGEEYFRLKEKELLRE-LVERDNVVVATGGGV 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 743680319 218 VSEAQTYErVLRTFRTVWLRARPDVHFQRVMQQNdariatEALRNEALEHIHRMLDAREALYQLADvTLDTSDIT 292
Cdd:PRK13951  81 VIDPENRE-LLKKEKTLFLYAPPEVLMERVTTEN------RPLLREGKERIREIWERRKQFYTEFR-GIDTSKLN 147
PRK13949 PRK13949
shikimate kinase; Provisional
 137-292 3.50e-20

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 85.55  E-value: 3.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 137 RRIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERiIAEHDNVVLATGGG 216
Cdd:PRK13949   2 ARIFLVGYMGAGKTTLGKALARELGLSFIDLDFFIENRFHKTVGDIFAERGEAVFRELERNMLHE-VAEFEDVVISTGGG 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 743680319 217 IVSEAQTYERVLRTFRTVWLRARPDVHFQR--VMQQNDARIATEAlRNEALEHIHRMLDAREALYQLADVTLDTSDIT 292
Cdd:PRK13949  81 APCFFDNMELMNASGTTVYLKVSPEVLFVRlrLAKQQRPLLKGKS-DEELLDFIIEALEKRAPFYRQAKIIFNADKLE 157
aroK PRK05057
shikimate kinase AroK;
137-292 6.22e-19

shikimate kinase AroK;


Pssm-ID: 235335 [Multi-domain]  Cd Length: 172  Bit Score: 82.45  E-value: 6.22e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 137 RRIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERiIAEHDNVVLATGGG 216
Cdd:PRK05057   5 RNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADIGWVFDVEGEEGFRDREEKVINE-LTEKQGIVLATGGG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 217 IVSEAQTYERVLRTFRTVWLRARPDVHFQR--------VMQQNDARIATEALRNEalehihrmldaREALY-QLADVTLD 287
Cdd:PRK05057  84 SVKSRETRNRLSARGVVVYLETTIEKQLARtqrdkkrpLLQVDDPREVLEALANE-----------RNPLYeEIADVTIR 152


                 ....*
gi 743680319 288 TSDIT 292
Cdd:PRK05057 153 TDDQS 157
PRK13948 PRK13948
shikimate kinase; Provisional
 139-288 7.33e-17

shikimate kinase; Provisional


Pssm-ID: 184413 [Multi-domain]  Cd Length: 182  Bit Score: 76.75  E-value: 7.33e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 139 IALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIaEHDNVVLATGGGIV 218
Cdd:PRK13948  13 VALAGFMGTGKSRIGWELSRALMLHFIDTDRYIERVTGKSIPEIFRHLGEAYFRRCEAEVVRRLT-RLDYAVISLGGGTF 91

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 219 SEAQTYERVLRTFRTVWLRARPDVHFQRVMQQNDARIATEalrnEALEHIHRMLDAREALYQLADVTLDT 288
Cdd:PRK13948  92 MHEENRRKLLSRGPVVVLWASPETIYERTRPGDRPLLQVE----DPLGRIRTLLNEREPVYRQATIHVST 157
aroL PRK03731
shikimate kinase AroL;
138-280 7.20e-14

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 68.43  E-value: 7.20e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 138 RIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEhdNVVLATGGGI 217
Cdd:PRK03731   4 PLFLVGARGCGKTTVGMALAQALGYRFVDTDQWLQSTSNMTVAEIVEREGWAGFRARESAALEAVTAP--STVIATGGGI 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 743680319 218 VSEAQTYERVLRTFRTVWLRARPDVHFQRVMQ--QNDARiatEALRNEAL-EHIHRMLDAREALYQ 280
Cdd:PRK03731  82 ILTEENRHFMRNNGIVIYLCAPVSVLANRLEAnpEEDQR---PTLTGKPIsEEVAEVLAEREALYR 144
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
33-94 2.34e-13

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 64.63  E-value: 2.34e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 743680319  33 LARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETLVAE 94
Cdd:COG1396    8 LGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGG 69
PRK14021 PRK14021
bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional
 141-305 2.42e-13

bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional


Pssm-ID: 184458 [Multi-domain]  Cd Length: 542  Bit Score: 70.28  E-value: 2.42e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 141 LIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREAGIAIGEVITLYGQAAMRRIERQCIERIIAEHDNVVLATGGGIVSE 220
Cdd:PRK14021  11 IIGMMGAGKTRVGKEVAQMMRLPFADADVEIEREIGMSIPSYFEEYGEPAFREVEADVVADMLEDFDGIFSLGGGAPMTP 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 221 AqtYERVLRTF-----RTVWLRARPDVHFQRVMQQNDARIateaLRNEALEHIHRMLDAREALY-QLADVTLDTSDITPD 294
Cdd:PRK14021  91 S--TQHALASYiahggRVVYLDADPKEAMERANRGGGRPM----LNGDANKRWKKLFKQRDPVFrQVANVHVHTRGLTPQ 164

                        170
                 ....*....|.
gi 743680319 295 AALAALQDTLS 305
Cdd:PRK14021 165 AAAKKLIDMVA 175
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
33-94 3.18e-11

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 57.94  E-value: 3.18e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 743680319  33 LARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETLVAE 94
Cdd:COG1476    5 LGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSL 66
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 34-91 1.35e-10

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 56.02  E-value: 1.35e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 743680319  34 ARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETL 91
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
36-91 6.34e-10

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 54.06  E-value: 6.34e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 743680319    36 RVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETL 91
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 33-86 7.26e-10

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 54.17  E-value: 7.26e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 743680319  33 LARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNV 86
Cdd:COG1813   13 YGERIREAREARGLSQEELAEKLGVSESTIRRIERGEATPSLDTLRKLEKALGI 66
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 37-91 6.62e-09

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 51.39  E-value: 6.62e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 743680319   37 VRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETL 91
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
PLN02199 PLN02199
shikimate kinase
 136-310 3.25e-08

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 53.93  E-value: 3.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 136 GRRIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEREA-GIAIGEVITLYGQAAMRRIERQCIERIIAEHdNVVLATG 214
Cdd:PLN02199 102 GRSMYLVGMMGSGKTTVGKLMSKVLGYTFFDCDTLIEQAMnGTSVAEIFVHHGENFFRGKETDALKKLSSRY-QVVVSTG 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 215 GGIVSEAQTYERVLRTFrTVWLrarpDVHFQrVMQQNDARIATEA---LRNE-------ALEHIHRMLDAREALYQLADV 284
Cdd:PLN02199 181 GGAVIRPINWKYMHKGI-SIWL----DVPLE-ALAHRIAAVGTDSrplLHDEsgdaysvAFKRLSAIWDERGEAYTNANA 254

                        170       180
                 ....*....|....*....|....*.
gi 743680319 285 TLDTSDITPDAALAALQDtLSPARAA 310
Cdd:PLN02199 255 RVSLENIAAKRGYKNVSD-LTPTEIA 279
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
139-300 7.27e-08

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 51.07  E-value: 7.27e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 139 IALIGLRGAGKSTLGPRLAQAFGAPFveLDKEVEREAGIAIGEVITLYGQAAMRRIER---QCIERIIAEHDNVVLATGG 215
Cdd:COG0645    2 ILVCGLPGSGKSTLARALAERLGAVR--LRSDVVRKRLFGAGLAPLERSPEATARTYArllALARELLAAGRSVILDATF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 216 GIVSEAQTYERVLR----TFRTVWLRARPDVHFQRVMQQNDARIATEAlRNEALEHIHRMLDAREALYQlADVTLDTSDi 291
Cdd:COG0645   80 LRRAQREAFRALAEeagaPFVLIWLDAPEEVLRERLEARNAEGGDSDA-TWEVLERQLAFEEPLTEDEG-FLLVVDTSG- 156


                 ....*....
gi 743680319 292 tPDAALAAL 300
Cdd:COG0645  157 -LEEALAAL 164
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
146-296 1.85e-07

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 50.59  E-value: 1.85e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 146 GAGKSTLGPRLAQAFGAPFV--ELDKEVEREAGIAIGEVITL--------YGQAAMRRIERQCIERII---AEHDNVVLA 212
Cdd:COG1102   10 GSGGTTIAKRLAEKLGLPLYdgEILREAAKERGLSEEEFEKLdekapsllYRDTAEEDEIDRALDKVIrelARKGNCVIV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 213 T-GGGIVseAQTYERVLRtfrtVWLRARPDVHFQRVMQQNDARiatealRNEALEHIHRMLDAREALYQ----------- 280
Cdd:COG1102   90 GrLADWI--LRDRPNVLK----VFLTAPLEVRVKRIAEREGIS------EEEAEKEIKKRDKSRAKYYKyyygidwgdps 157

                        170
                 ....*....|....*.
gi 743680319 281 LADVTLDTSDITPDAA 296
Cdd:COG1102  158 NYDLVINTSRLGIEEA 173
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 33-92 1.03e-06

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 46.17  E-value: 1.03e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  33 LARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETLV 92
Cdd:COG3620   18 LGEALRLMRKELGLSQLPVAELVGVSQSDILRIESGKRDPTVSTLEKIAEALGKELSAVL 77
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 33-89 1.81e-06

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 44.44  E-value: 1.81e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 743680319   33 LARRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAG-TGNVSLAVLHKLGEALNVGVE 89
Cdd:pfam13560   2 LGARLRRLRERAGLSQEALARRLGVSRSTLSRLETGrRGRPSPAVVERLARALGVDGA 59
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
36-92 2.29e-06

DNA-binding transcriptional regulator, XRE family [Transcription];


Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 44.36  E-value: 2.29e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 743680319  36 RVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTG-NVSLAVLHKLGEALNVGVETLV 92
Cdd:COG3655    5 KLDELLAERGMTKKELAEATGISRATLSRLKNGKAkAVRLDTLEKICKALDCQPGDLL 62
PRK13890 PRK13890
conjugal transfer protein TrbA; Provisional
 43-91 1.55e-05

conjugal transfer protein TrbA; Provisional


Pssm-ID: 237547 [Multi-domain]  Cd Length: 120  Bit Score: 43.59  E-value: 1.55e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 743680319  43 QRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETL 91
Cdd:PRK13890  16 ERHMTKKELSERSGVSISFLSDLTTGKANPSLKVMEAIADALETPLPLL 64
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
 36-92 2.72e-05

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 41.37  E-value: 2.72e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 743680319   36 RVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGT-GNVSLAVLHKLGEALNVGVETLV 92
Cdd:pfam13443   1 KLRKLMADRGISKSDLARATGISRATLSRLRKGKpKRVSLDTLDKICDALGCQPGDLL 58
Cytidylate_kin2 pfam13189
Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.
 139-289 3.64e-04

Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.


Pssm-ID: 433023 [Multi-domain]  Cd Length: 176  Bit Score: 40.69  E-value: 3.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  139 IALIGLRGAGKSTLGPRLAQAFGAPFV--ELDKEVEREAGIAI-------------GEVITLYG---------QAAMRRI 194
Cdd:pfam13189   2 ITISRQYGSGGTTIAKKLAEKLGYPFYdrEILDEIAKELGISEeefelfdeksrlsSFLYSLAGgrvrgdalsDDRLFDA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  195 ERQCIERIIAEHDNVVLATGGGIVseAQTYERVLRtfrtVWLRARPDVHFQRVMQQNDARiatealRNEALEHIHRMLDA 274
Cdd:pfam13189  82 QSKVIRELAAEDNCVIVGRGADYI--LKDIPNVLR----VFLTAPLEDRVKRVMEREGLS------EEEARELIKETDKR 149

                         170       180
                  ....*....|....*....|....*.
gi 743680319  275 REALYQ-----------LADVTLDTS 289
Cdd:pfam13189 150 RAKYYKyytgkdwgdaeNYDLVINTS 175
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 138-289 6.60e-04

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 39.39  E-value: 6.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 138 RIALIGLRGAGKSTLGPRLAQAFGAPFV---ELDKEverEAGIAIGEVitlygqAAMRRI-----ERQcieRIIAEHDNV 209
Cdd:cd02020    1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLdtgGIRTE---EVGKLASEV------AAIPEVrkaldERQ---RELAKKPGI 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 210 VLAtGGGIVSEAQTYERVlrtfrTVWLRARPDVHFQRVMQQNDARIATEALrNEALEHIhRMLDARE-----ALYQLA-- 282
Cdd:cd02020   69 VLE-GRDIGTVVFPDADL-----KIFLTASPEVRAKRRAKQLQAKGEGVDL-EEILAEI-IERDERDstryvAPLKLAed 140


                 ....*..
gi 743680319 283 DVTLDTS 289
Cdd:cd02020  141 AIVIDTS 147
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 139-278 1.10e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 38.83  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  139 IALIGLRGAGKSTLGPRLAQAFGAPFVELDKEVEReagIAIGEVITLYGQAAMRRIERQCIERIIAEhdnvVLATGGGIV 218
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSSDDERKR---LFGEGRPSISYYTDATDRTYERLHELARI----ALRAGRPVI 74

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 743680319  219 -----SEAQTYERVLRTFRT-------VWLRARPDVHFQRVMQQNDARIATEALRNEALEhihRMLDAREAL 278
Cdd:pfam13671  75 ldatnLRRDERARLLALAREygvpvriVVFEAPEEVLRERLAARARAGGDPSDVPEEVLD---RQKARFEPP 143
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 35-91 1.48e-03

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 36.50  E-value: 1.48e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 743680319   35 RRVRTLRAQRGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETL 91
Cdd:pfam12844   2 ERLRKAREERGLTQEELAERLGISRSQLSAIENGKSVPPAETLYKIAELLGVPANWL 58
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
 44-99 1.78e-03

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 36.71  E-value: 1.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 743680319  44 RGMTRKQLAAQSGVSLPYLARVEAGTGNVSLAVLHKLGEALNVGVETLVAERMAYD 99
Cdd:COG3093   21 LGLSQTELAKALGVSRQRISEILNGKRAITADTALRLARAFGTSAEFWLNLQAAYD 76
AAA_18 pfam13238
AAA domain;
139-247 3.09e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 37.02  E-value: 3.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319  139 IALIGLRGAGKSTLGPRLAQAFGapFVELDKEVEREAGIAIGEVITLYGQAAMRR----IERQCIERIIA--EHDNVVLA 212
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLG--FGDNVRDLALENGLVLGDDPETRESKRLDEdkldRLLDLLEENAAleEGGNLIID 78

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 743680319  213 tggGIVSEAQTYERVLRTFrtVWLRARPDVHFQRV 247
Cdd:pfam13238  79 ---GHLAELEPERAKDLVG--IVLRASPEELLERL 108
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 139-168 4.26e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 37.23  E-value: 4.26e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 743680319 139 IALIGLRGAGKSTLGPRLAQAFGAPFVELD 168
Cdd:cd02021    2 IVVMGVSGSGKSTVGKALAERLGAPFIDGD 31
PRK04182 PRK04182
cytidylate kinase; Provisional
 138-297 4.72e-03

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 37.48  E-value: 4.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 138 RIALIGLRGAGKSTLGPRLAQAFGAPFV---ELDKEVEREAGIAIGEvitLYGQAAM-----RRIERQCIErIIAEHDNV 209
Cdd:PRK04182   2 IITISGPPGSGKTTVARLLAEKLGLKHVsagEIFRELAKERGMSLEE---FNKYAEEdpeidKEIDRRQLE-IAEKEDNV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743680319 210 VLAT--GGGIVSEAQTYervlrtfrTVWLRARPDVHFQRVMQQNDARIatealrNEALEHIHrmldAREAL--------- 278
Cdd:PRK04182  78 VLEGrlAGWMAKDYADL--------KIWLKAPLEVRAERIAEREGISV------EEALEETI----EREESeakrykeyy 139

                        170       180
                 ....*....|....*....|....*
gi 743680319 279 ------YQLADVTLDTSDITPDAAL 297
Cdd:PRK04182 140 gididdLSIYDLVINTSRWDPEGVF 164
Dck COG1428
Deoxyadenosine/deoxycytidine kinase [Nucleotide transport and metabolism];
135-162 5.33e-03

Deoxyadenosine/deoxycytidine kinase [Nucleotide transport and metabolism];


Pssm-ID: 441037 [Multi-domain]  Cd Length: 205  Bit Score: 37.46  E-value: 5.33e-03
                         10        20
                 ....*....|....*....|....*...
gi 743680319 135 KGRRIALIGLRGAGKSTLGPRLAQAFGA 162
Cdd:COG1428    2 KPRYIAVEGNIGAGKTTLARLLAEHLGA 29
NK cd02019
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
 138-171 6.06e-03

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


Pssm-ID: 238977 [Multi-domain]  Cd Length: 69  Bit Score: 35.00  E-value: 6.06e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 743680319 138 RIALIGLRGAGKSTLGPRLAQAFGAPFVELDKEV 171
Cdd:cd02019    1 IIAITGGSGSGKSTVAKKLAEQLGGRSVVVLDEI 34
PRK07261 PRK07261
DNA topology modulation protein;
138-169 9.53e-03

DNA topology modulation protein;


Pssm-ID: 180911 [Multi-domain]  Cd Length: 171  Bit Score: 36.23  E-value: 9.53e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 743680319 138 RIALIGLRGAGKSTLGPRLAQAFGAPFVELDK 169
Cdd:PRK07261   2 KIAIIGYSGSGKSTLARKLSQHYNCPVLHLDT 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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