NCBI Conserved Domain Search

Conserved domains on [gi|694160455|gb|AIS53884|]

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sugar ABC transporter ATP-binding protein [Vibrio coralliilyticus]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11418519)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including dipeptides and oligopeptides

CATH: 3.40.50.300

Gene Ontology: GO:0042626|GO:0140359|GO:0016887

PubMed: 25750732|24638992

SCOP: 4003976

TCDB: 3.A.1

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

5-320

7.06e-166

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 464.14 E-value: 7.06e-166

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfITGGEVIFNGENILNYSDER 84
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPG-ITSGEILFDGEDLLKLSEKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHP--SRLTDYPHQFSGGMRQRL 162
Cdd:COG0444   80 LRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDpeRRLDRYPHELSGGMRQRV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 163 VIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:COG0444  160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 243 ESPYHPYTKGLGSSFPPLTGPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPTQLKQIEPSRFSNCHLYGE 320
Cdd:COG0444  240 ENPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCREEEPPLREVGPGHRVACHLYEE 317

Name

Accession

Description

Interval

E-value

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

5-320

7.06e-166

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 464.14 E-value: 7.06e-166

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfITGGEVIFNGENILNYSDER 84
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPG-ITSGEILFDGEDLLKLSEKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHP--SRLTDYPHQFSGGMRQRL 162
Cdd:COG0444   80 LRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDpeRRLDRYPHELSGGMRQRV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 163 VIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:COG0444  160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 243 ESPYHPYTKGLGSSFPPLTGPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPTQLKQIEPSRFSNCHLYGE 320
Cdd:COG0444  240 ENPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCREEEPPLREVGPGHRVACHLYEE 317

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

5-236

1.77e-106

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 310.21 E-value: 1.77e-106

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYsDER 84
Cdd:cd03257    1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKP----TSGSIIFDGKDLLKL-SRR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGL-LEIVDIHPSRLTDYPHQFSGGMRQRLV 163
Cdd:cd03257   76 LRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLlLVGVGLPEEVLNRYPHELSGGQRQRVA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:cd03257  156 IARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

4-316

1.30e-102

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 304.34 E-value: 1.30e-102

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfITGGEVIFNGENILNYSDE 83
Cdd:PRK09473  11 ALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANG-RIGGSATFNGREILNLPEK 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RMQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPS--RLTDYPHQFSGGMRQR 161
Cdd:PRK09473  90 ELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEArkRMKMYPHEFSGGMRQR 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQI 241
Cdd:PRK09473 170 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDV 249

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 242 LESPYHPYTKGLGSSFPPLTGPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPtQLKQIEPSRFSNCH 316
Cdd:PRK09473 250 FYQPSHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAP-PLEEFGPGRLRACF 323

nickel_nikD

TIGR02770

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...

27-253

1.54e-62

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 198.36 E-value: 1.54e-62

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFITGGEVIFNGENILNYSdermqaFRWSEMSMVFQSAMNALNP 106
Cdd:TIGR02770   4 DLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILLDGRPLLPLS------IRGRHIATIMQNPRTAFNP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  107 VLPMEEQFCDVIMRHTNMTReQARKRAEGLLEIVDI-HPSRLTD-YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTAL 184
Cdd:TIGR02770  78 LFTMGNHAIETLRSLGKLSK-QARALILEALEAVGLpDPEEVLKkYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDL 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455  185 DVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPYTKGL 253
Cdd:TIGR02770 157 DVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKL 225

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

26-182

1.74e-34

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 123.14 E-value: 1.74e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDERMQAFRwSEMSMVFQSamNALN 105
Cdd:pfam00005   2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSP----TEGTILLDGQDL---TDDERKSLR-KEIGYVFQD--PQLF 71

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455  106 PVLPMEEQFCDVIMRHTNMTREQARKRAEGL--LEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTT 182
Cdd:pfam00005  72 PRLTVRENLRLGLLLKGLSKREKDARAEEALekLGLGDLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

ABC_ATP_SaoA

NF040729

ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC ...

6-227

8.43e-30

ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC transporter in which both the permease subunit SaoP, and the substrate-binding protein SaoB, are nearly always selenoproteins that were unrecognized as such until recently (2022). The SAO system is found in Clostridium difficile and various other anaerobic heterotrophs.

Pssm-ID: 468693 [Multi-domain] Cd Length: 248 Bit Score: 114.07 E-value: 8.43e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERm 85
Cdd:NF040729   2 LKIQNISKTFINNKKENEVLKDISFDVEEGEFVSLLGPSGCGKTTLLTIIAGFQNA----TSGEILVNGNEVTKPGPDR- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 qAFrwsemsmVFQSAmnALNPVLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIvdihpSRLTD----YPHQFSGGMRQR 161
Cdd:NF040729  77 -GF-------VFQNY--ALFPWMTVKENI-EYPMKQQKMPKQEREKRLNELLEM-----AQLTGkenlYPHQISGGMKQR 140

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVqREILQK-IYALKEEFGFSILFITHDLSLMVEFSDRIGIM 227
Cdd:NF040729 141 TAVIRALACKPEVLLMDEPLGAVDFQM-RQILQEeLESIWLKDKTTVLMVTHDVDEAVYLSDRVIVM 206

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

20-231

1.16e-12

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 68.61 E-value: 1.16e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVafslMrlhK------PP----AFITGGEVifNGENIlnysDERM---- 85
Cdd:NF033858 277 GDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTT----M---KmltgllPAsegeAWLFGQPV--DAGDI----ATRRrvgy 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 --QAFR-WSEMSmVFQsamnalNPVLpmeeqfcdvimrHT---NMTREQARKRAEGLLEIVDihpsrLTDYPHQFSG--- 156
Cdd:NF033858 344 msQAFSlYGELT-VRQ------NLEL------------HArlfHLPAAEIAARVAEMLERFD-----LADVADALPDslp 399

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 157 -GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSIlFI-THdlsLMVEFS--DRIGIMYSGE 231
Cdd:NF033858 400 lGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTI-FIsTH---FMNEAErcDRISLMHAGR 474

GguA

NF040905

sugar ABC transporter ATP-binding protein;

22-234

3.79e-12

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 66.74 E-value: 3.79e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  22 VRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHkpPAFITGGEVIFNGEnILNYSDermqaFRWSE---MS 94
Cdd:NF040905  14 VKALDDVNLSVREGEIHALCGENGAGKST----LMKvlsgVY--PHGSYEGEILFDGE-VCRFKD-----IRDSEalgIV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  95 MVFQSAmnALNPVLPMEEqfcdvimrhtNM--TREQAR----------KRAEGLLEIV--DIHPS-RLTDYphqfsGGMR 159
Cdd:NF040905  82 IIHQEL--ALIPYLSIAE----------NIflGNERAKrgvidwnetnRRARELLAKVglDESPDtLVTDI-----GVGK 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 160 QRLV-IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILfITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:NF040905 145 QQLVeIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSII-ISHKLNEIRRVADSITVLRDGRTIE 219

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

20-216

5.38e-11

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 60.71 E-value: 5.38e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERmqafrwsemsmvfqs 99
Cdd:NF040873   3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRP----TSGTVRRAGGARVAYVPQR--------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 amNALNPVLPMEEQFCdVIM---RHTNMTRE---QARKRAEGLLEIVDIHpsRLTDYP-HQFSGGMRQRLVIAIALALNP 172
Cdd:NF040873  64 --SEVPDSLPLTVRDL-VAMgrwARRGLWRRltrDDRAAVDDALERVGLA--DLAGRQlGELSGGQRQRALLAQGLAQEA 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 694160455 173 KMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSL 216
Cdd:NF040873 139 DLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLEL 181

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

20-233

3.03e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 60.52 E-value: 3.03e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFslmrlhkpPAFITGGEvifngenilnySDERMQAFR-WSEMSMVFQ 98
Cdd:NF000106  24 GEVKAVDGVDLDVREGTVLGVLGP*GAA**RGAL--------PAHV*GPD-----------AGRRPWRF*tWCANRRALR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  99 SAMNALNPVLP-MEEQFCD-----VIMRHTNMTREQARKRAEGLLEIVDIHPSRlTDYPHQFSGGMRQRLVIAIALALNP 172
Cdd:NF000106  85 RTIG*HRPVR*gRRESFSGrenlyMIGR*LDLSRKDARARADELLERFSLTEAA-GRAAAKYSGGMRRRLDLAASMIGRP 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 173 KMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:NF000106 164 AVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVI 223

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

34-213

3.77e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 54.69 E-value: 3.77e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    34 PGEVFGLAGESGCGKSTVAFSLMRLHKPPafiTGGEVIFNGENILNYSDERMQAFRwsemsmvfqsamnalnpvlpmeeq 113
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPP---GGGVIYIDGEDILEEVLDQLLLII------------------------ 53

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   114 fcdvimrhtnmtreqarkraeglleivdihpsrLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREIL 193
Cdd:smart00382  54 ---------------------------------VGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLL 100

                          170       180
                   ....*....|....*....|....*
gi 694160455   194 QKIYA-----LKEEFGFSILFITHD 213
Cdd:smart00382 101 LLEELrllllLKSEKNLTVILTTND 125

GguA

NF040905

sugar ABC transporter ATP-binding protein;

155-236

6.26e-05

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 44.40 E-value: 6.26e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI- 233
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLGMCDRIYVMNEGRITg 484


                 ...
gi 694160455 234 EVA 236
Cdd:NF040905 485 ELP 487

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

6-185

1.02e-04

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 43.96 E-value: 1.02e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITG------GEVIFNGENILN 79
Cdd:NF033858   2 ARLEGVSHRY----GKTVALDDVSLDIPAGCMVGLIGPDGVGKSS----LLSL------IAGarkiqqGRVEVLGGDMAD 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 YSDERMQAFRWSEMSmvfQSAMNALNPVLPMEE--QFcdvIMRHTNMTREQARKRAEGLLEIVDIHPSRltDYPH-QFSG 156
Cdd:NF033858  68 ARHRRAVCPRIAYMP---QGLGKNLYPTLSVFEnlDF---FGRLFGQDAAERRRRIDELLRATGLAPFA--DRPAgKLSG 139

                        170       180
                 ....*....|....*....|....*....
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALD 185
Cdd:NF033858 140 GMKQKLGLCCALIHDPDLLILDEPTTGVD 168

Name

Accession

Description

Interval

E-value

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

5-320

7.06e-166

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 464.14 E-value: 7.06e-166

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfITGGEVIFNGENILNYSDER 84
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPG-ITSGEILFDGEDLLKLSEKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHP--SRLTDYPHQFSGGMRQRL 162
Cdd:COG0444   80 LRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDpeRRLDRYPHELSGGMRQRV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 163 VIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:COG0444  160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 243 ESPYHPYTKGLGSSFPPLTGPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPTQLKQIEPSRFSNCHLYGE 320
Cdd:COG0444  240 ENPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCREEEPPLREVGPGHRVACHLYEE 317

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

1-253

1.16e-109

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 328.95 E-value: 1.16e-109

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFITGGEVIFNGENILNY 80
Cdd:COG4172    2 MSMPLLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHPSGSILFDGQDLLGL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHP--SRLTDYPHQFSGGM 158
Cdd:COG4172   82 SERELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDpeRRLDAYPHQLSGGQ 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPS 238
Cdd:COG4172  162 RQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPT 241

                        250
                 ....*....|....*
gi 694160455 239 KQILESPYHPYTKGL 253
Cdd:COG4172  242 AELFAAPQHPYTRKL 256

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

1-321

1.41e-109

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 321.68 E-value: 1.41e-109

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDY-------ITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFN 73
Cdd:COG4608    3 MAEPLLEVRDLKKHFpvrgglfGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEP----TSGEILFD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  74 GENILNYSDERMQAFRwSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQ 153
Cdd:COG4608   79 GQDITGLSGRELRPLR-RRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSlMVE-FSDRIGIMYSGEL 232
Cdd:COG4608  158 FSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLS-VVRhISDRVAVMYLGKI 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 233 IEVAPSKQILESPYHPYTKGLGSSFpPLTGPKTK-----LTGIPGNPLNlleIPQGCRFQARCDRVHEACTKIPTQLKQI 307
Cdd:COG4608  237 VEIAPRDELYARPLHPYTQALLSAV-PVPDPERRrerivLEGDVPSPLN---PPSGCRFHTRCPYAQDRCATEEPPLREV 312

                        330
                 ....*....|....
gi 694160455 308 EPSRFSNCHLYGEP 321
Cdd:COG4608  313 GPGHQVACHLAEEG 326

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

5-236

1.77e-106

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 310.21 E-value: 1.77e-106

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYsDER 84
Cdd:cd03257    1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKP----TSGSIIFDGKDLLKL-SRR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGL-LEIVDIHPSRLTDYPHQFSGGMRQRLV 163
Cdd:cd03257   76 LRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLlLVGVGLPEEVLNRYPHELSGGQRQRVA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:cd03257  156 IARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

1-260

2.08e-103

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 312.61 E-value: 2.08e-103

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDY-ITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILN 79
Cdd:COG1123  256 AAEPLLEVRNLSKRYpVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRP----TSGSILFDGKDLTK 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 YSDERMQAFRwSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMR 159
Cdd:COG1123  332 LSRRSLRELR-RRVQMVFQDPYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDLADRYPHELSGGQR 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 160 QRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSK 239
Cdd:COG1123  411 QRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTE 490

                        250       260
                 ....*....|....*....|.
gi 694160455 240 QILESPYHPYTKGLGSSFPPL 260
Cdd:COG1123  491 EVFANPQHPYTRALLAAVPSL 511

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

4-316

1.30e-102

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 304.34 E-value: 1.30e-102

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfITGGEVIFNGENILNYSDE 83
Cdd:PRK09473  11 ALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANG-RIGGSATFNGREILNLPEK 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RMQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPS--RLTDYPHQFSGGMRQR 161
Cdd:PRK09473  90 ELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEArkRMKMYPHEFSGGMRQR 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQI 241
Cdd:PRK09473 170 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDV 249

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 242 LESPYHPYTKGLGSSFPPLTGPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPtQLKQIEPSRFSNCH 316
Cdd:PRK09473 250 FYQPSHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAP-PLEEFGPGRLRACF 323

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

1-280

1.40e-87

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 271.78 E-value: 1.40e-87

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTaPLISIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFItGGEVIFNGENILNY 80
Cdd:COG1123    1 MT-PLLEVRDLSVRY--PGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGRI-SGEVLLDGRDLLEL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDermqAFRWSEMSMVFQSAMNALNPVlPMEEQFCDVImRHTNMTREQARKRAEGLLEIVDIhPSRLTDYPHQFSGGMRQ 160
Cdd:COG1123   77 SE----ALRGRRIGMVFQDPMTQLNPV-TVGDQIAEAL-ENLGLSRAEARARVLELLEAVGL-ERRLDRYPHQLSGGQRQ 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 161 RLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQ 240
Cdd:COG1123  150 RVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEE 229

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 694160455 241 ILESPyhpytKGLgSSFPPLTGPKTKLTGIPGNPLNLLEI 280
Cdd:COG1123  230 ILAAP-----QAL-AAVPRLGAARGRAAPAAAAAEPLLEV 263

DppF

COG1124

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

5-253

8.99e-82

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 248.18 E-value: 8.99e-82

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDER 84
Cdd:COG1124    1 MLEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERP----WSGEVTFDGRPV---TRRR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwSEMSMVFQSAMNALNPVLPMEeqfcDVI---MRHTNMTREQARkrAEGLLEIVDIHPSRLTDYPHQFSGGMRQR 161
Cdd:COG1124   74 RKAFR-RRVQMVFQDPYASLHPRHTVD----RILaepLRIHGLPDREER--IAELLEQVGLPPSFLDRYPHQLSGGQRQR 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQI 241
Cdd:COG1124  147 VAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADL 226

                        250
                 ....*....|..
gi 694160455 242 LESPYHPYTKGL 253
Cdd:COG1124  227 LAGPKHPYTREL 238

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

3-253

1.25e-77

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 246.52 E-value: 1.25e-77

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVDYIT-------AAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafiTGGEVIFNGE 75
Cdd:COG4172  273 PPLLEARDLKVWFPIkrglfrrTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-----SEGEIRFDGQ 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  76 NILNYSDERMQAFRwSEMSMVFQSAMNALNPVLPMEEqfcdVI---MR--HTNMTREQARKRAEGLLEIVDIHPSRLTDY 150
Cdd:COG4172  348 DLDGLSRRALRPLR-RRMQVVFQDPFGSLSPRMTVGQ----IIaegLRvhGPGLSAAERRARVAEALEEVGLDPAARHRY 422

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 151 PHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSG 230
Cdd:COG4172  423 PHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDG 502

                        250       260
                 ....*....|....*....|...
gi 694160455 231 ELIEVAPSKQILESPYHPYTKGL 253
Cdd:COG4172  503 KVVEQGPTEQVFDAPQHPYTRAL 525

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

1-267

1.05e-76

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 244.23 E-value: 1.05e-76

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRL-HKPPAFITGGEVIFNGENILN 79
Cdd:PRK15134   1 MTQPLLAIENLSVAFRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLlPSPPVVYPSGDIRFHGESLLH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 YSDERMQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIH--PSRLTDYPHQFSGG 157
Cdd:PRK15134  81 ASEQTLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRqaAKRLTDYPHQLSGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAP 237
Cdd:PRK15134 161 ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNR 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 694160455 238 SKQILESPYHPYTKGLGSSFP-----PLTGPKTKL 267
Cdd:PRK15134 241 AATLFSAPTHPYTQKLLNSEPsgdpvPLPEPASPL 275

SapD

COG4170

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

4-316

1.49e-75

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 235.18 E-value: 1.49e-75

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFITGGEVIFNGENILNYSDE 83
Cdd:COG4170    2 PLLDIRNLTIEIDTPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNWHVTADRFRWNGIDLLKLSPR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RMQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTN----MTREQARK-RAEGLLEIVDI--HPSRLTDYPHQFSG 156
Cdd:COG4170   82 ERRKIIGREIAMIFQEPSSCLDPSAKIGDQLIEAIPSWTFkgkwWQRFKWRKkRAIELLHRVGIkdHKDIMNSYPHELTE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:COG4170  162 GECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESG 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 237 PSKQILESPYHPYTKGLGSSFPPLTGP---KTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPtQLKQIEPSRFS 313
Cdd:COG4170  242 PTEQILKSPHHPYTKALLRSMPDFRQPlphKSRLNTLPGSIPPLQHLPIGCRLGPRCPYAQKKCVETP-RLRKIKGHEFA 320


                 ...
gi 694160455 314 nCH 316
Cdd:COG4170  321 -CH 322

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

1-316

6.79e-75

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 233.32 E-value: 6.79e-75

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDY------ITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNG 74
Cdd:PRK11308   1 SQQPLLQAIDLKKHYpvkrglFKPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETP----TGGELYYQG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  75 ENILNYSDERMQAFRwSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQF 154
Cdd:PRK11308  77 QDLLKADPEAQKLLR-QKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLRPEHYDRYPHMF 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:PRK11308 156 SGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVE 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 235 VAPSKQILESPYHPYTKGLGSS----FPPLTGPKTKLTGIPGNPLNlleIPQGCRFQARCDRVHEACTKIPTQLKQIEPS 310
Cdd:PRK11308 236 KGTKEQIFNNPRHPYTQALLSAtprlNPDDRRERIKLTGELPSPLN---PPPGCAFNARCPRAFGRCRQEQPQLRDYDGR 312


                 ....*.
gi 694160455 311 RFSnCH 316
Cdd:PRK11308 313 LVA-CF 317

dppD

PRK11022

dipeptide transporter ATP-binding subunit; Provisional

5-316

9.17e-73

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 227.70 E-value: 9.17e-73

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFITGGEVIFNGENILNYSDER 84
Cdd:PRK11022   3 LLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIH--PSRLTDYPHQFSGGMRQRL 162
Cdd:PRK11022  83 RRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPdpASRLDVYPHQLSGGMSQRV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 163 VIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:PRK11022 163 MIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIF 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 243 ESPYHPYTKGLGSSFPPLTGPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPTQLKQIePSRFSNCH 316
Cdd:PRK11022 243 RAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALNML-AGRQSKCH 315

PRK15079

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

4-299

7.37e-69

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 218.04 E-value: 7.37e-69

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAAGD---------VRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafITGGEVIFNG 74
Cdd:PRK15079   7 VLLEVADLKVHFDIKDGKqwfwqppktLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVK----ATDGEVAWLG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  75 ENILNYSDERMQAFRwSEMSMVFQSAMNALNPVLPMEeqfcDVIMR-----HTNMTREQARKRAEGLLEIVDIHPSRLTD 149
Cdd:PRK15079  83 KDLLGMKDDEWRAVR-SDIQMIFQDPLASLNPRMTIG----EIIAEplrtyHPKLSRQEVKDRVKAMMLKVGLLPNLINR 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 150 YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYS 229
Cdd:PRK15079 158 YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYL 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 230 GELIEVAPSKQILESPYHPYTKGLGSSFpPLTGPKTK-------LTGIPGNPLNlleIPQGCRFQARCDRVHEACTK 299
Cdd:PRK15079 238 GHAVELGTYDEVYHNPLHPYTKALMSAV-PIPDPDLErnktiqlLEGELPSPIN---PPSGCVFRTRCPIAGPECAK 310

PhnK

COG4107

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and ...

1-256

6.35e-67

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and metabolism];

Pssm-ID: 443283 [Multi-domain] Cd Length: 262 Bit Score: 210.82 E-value: 6.35e-67

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTA---PLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAfSLMRLHKPPafiTGGEVIFNG--- 74
Cdd:COG4107    1 MTNeeqPLLSVRGLSKRYGPGCGTVVACRDVSFDLYPGEVLGIVGESGSGKSTLL-KCLYFDLAP---TSGSVYYRDrdg 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  75 --ENILNYSDERMQAFRWSEMSMVFQSAMNALNpvlpME--------EQFCDVIMRHTnmtrEQARKRAEGLLEIVDIHP 144
Cdd:COG4107   77 gpRDLFALSEAERRRLRRTDWGMVYQNPRDGLR----MDvsaggniaERLMAAGERHY----GDIRARALEWLERVEIPL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 145 SRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRI 224
Cdd:COG4107  149 ERIDDLPRTFSGGMQQRVQIARALVTNPRLLFLDEPTTGLDVSVQARLLDLIRRLQRELGLSMIVVTHDLGVIRLLADRT 228

                        250       260       270
                 ....*....|....*....|....*....|..
gi 694160455 225 GIMYSGELIEVAPSKQILESPYHPYTKGLGSS 256
Cdd:COG4107  229 MVMKNGRVVESGLTDQVLEDPQHPYTQLLVSS 260

PRK10261

glutathione transporter ATP-binding protein; Provisional

5-260

1.31e-64

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 214.72 E-value: 1.31e-64

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRL-HKPPAFITGGEVIFNGEN-----IL 78
Cdd:PRK10261  12 VLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLlEQAGGLVQCDKMLLRRRSrqvieLS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDERMQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSR--LTDYPHQFSG 156
Cdd:PRK10261  92 EQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQtiLSRYPHQLSG 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:PRK10261 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETG 251

                        250       260
                 ....*....|....*....|....
gi 694160455 237 PSKQILESPYHPYTKGLGSSFPPL 260
Cdd:PRK10261 252 SVEQIFHAPQHPYTRALLAAVPQL 275

nickel_nikD

TIGR02770

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...

27-253

1.54e-62

Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 198.36 E-value: 1.54e-62

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFITGGEVIFNGENILNYSdermqaFRWSEMSMVFQSAMNALNP 106
Cdd:TIGR02770   4 DLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILLDGRPLLPLS------IRGRHIATIMQNPRTAFNP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  107 VLPMEEQFCDVIMRHTNMTReQARKRAEGLLEIVDI-HPSRLTD-YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTAL 184
Cdd:TIGR02770  78 LFTMGNHAIETLRSLGKLSK-QARALILEALEAVGLpDPEEVLKkYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDL 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455  185 DVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPYTKGL 253
Cdd:TIGR02770 157 DVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKL 225

PRK10261

glutathione transporter ATP-binding protein; Provisional

4-258

3.96e-61

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 205.47 E-value: 3.96e-61

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAAG-------DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGEN 76
Cdd:PRK10261 312 PILQVRNLVTRFPLRSGllnrvtrEVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVES----QGGEIIFNGQR 387

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  77 ILNYSDERMQAFRwSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSG 156
Cdd:PRK10261 388 IDTLSPGKLQALR-RDIQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEFSG 466

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:PRK10261 467 GQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546

                        250       260
                 ....*....|....*....|..
gi 694160455 237 PSKQILESPYHPYTKGLGSSFP 258
Cdd:PRK10261 547 PRRAVFENPQHPYTRKLMAAVP 568

MlaF

COG1127

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...

1-251

8.13e-60

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 191.73 E-value: 8.13e-60

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNY 80
Cdd:COG1127    1 MSEPMIEVRNLTKSF----GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRP----DSGEILVDGQDITGL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFRwSEMSMVFQSAmnAL--------NPVLPMEEqfcdvimrHTNMTREQARKRAEGLLEIVDihpsrLTD--- 149
Cdd:COG1127   73 SEKELYELR-RRIGMLFQGG--ALfdsltvfeNVAFPLRE--------HTDLSEAEIRELVLEKLELVG-----LPGaad 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 150 -YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMY 228
Cdd:COG1127  137 kMPSELSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLA 216

                        250       260
                 ....*....|....*....|...
gi 694160455 229 SGELIEVAPSKQILESPyHPYTK 251
Cdd:COG1127  217 DGKIIAEGTPEELLASD-DPWVR 238

PRK15093

peptide ABC transporter ATP-binding protein SapD;

4-316

3.99e-58

peptide ABC transporter ATP-binding protein SapD;

Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 190.40 E-value: 3.99e-58

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFITGGEVIFNGENILNYSDE 83
Cdd:PRK15093   2 PLLDIRNLTIEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSPR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RMQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQAR-----KRAEGLLEIVDI--HPSRLTDYPHQFSG 156
Cdd:PRK15093  82 ERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPGWTYKGRWWQRfgwrkRRAIELLHRVGIkdHKDAMRSFPYELTE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:PRK15093 162 GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETA 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 237 PSKQILESPYHPYTKGL-------GSSFPpltgPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPtQLKQIEP 309
Cdd:PRK15093 242 PSKELVTTPHHPYTQALiraipdfGSAMP----HKSRLNTLPGAIPLLEHLPIGCRLGPRCPYAQRECIETP-RLTGAKN 316


                 ....*..
gi 694160455 310 SRFSnCH 316
Cdd:PRK15093 317 HLYA-CH 322

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

5-259

3.92e-57

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 185.78 E-value: 3.92e-57

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    5 LISIRNLCVDYIT-----AAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILN 79
Cdd:TIGR02769   2 LLEVRDVTHTYRTgglfgAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKP----AQGTVSFRGQDLYQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   80 YSDERMQAFRwSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMR 159
Cdd:TIGR02769  78 LDRKQRRAFR-RDVQLVFQDSPSAVNPRMTVRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRSEDADKLPRQLSGGQL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  160 QRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSK 239
Cdd:TIGR02769 157 QRINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVA 236

                         250       260
                  ....*....|....*....|
gi 694160455  240 QILESPyHPYTKGLGSSFPP 259
Cdd:TIGR02769 237 QLLSFK-HPAGRNLQSAVLP 255

ABC_MJ0796_LolCDE_FtsE

cd03255

ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...

6-232

2.16e-56

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.

Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 182.30 E-value: 2.16e-56

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENILNYS 81
Cdd:cd03255    1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKST----LLNilggLDRP----TSGEVRVDGTDISKLS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQAFRWSEMSMVFQS-----AMNAL-NPVLPMeeqfcdvimRHTNMTREQARKRAEGLLEIVDIhPSRLTDYPHQFS 155
Cdd:cd03255   73 EKELAAFRRRHIGFVFQSfnllpDLTALeNVELPL---------LLAGVPKKERRERAEELLERVGL-GDRLNHYPSELS 142

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 156 GGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLmVEFSDRIGIMYSGEL 232
Cdd:cd03255  143 GGQQQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPEL-AEYADRIIELRDGKI 218

ABC_Pro_Gly_Betaine

cd03294

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...

16-249

3.88e-55

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 180.53 E-value: 3.88e-55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  16 ITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFRWSEMSM 95
Cdd:cd03294   31 LKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEP----TSGKVLIDGQDIAAMSRKELRELRRKKISM 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  96 VFQS-----AMNAL-NPVLPMEEQfcdvimrhtNMTREQARKRAEGLLEIVDIHPsRLTDYPHQFSGGMRQRLVIAIALA 169
Cdd:cd03294  107 VFQSfallpHRTVLeNVAFGLEVQ---------GVPRAEREERAAEALELVGLEG-WEHKYPDELSGGMQQRVGLARALA 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 170 LNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPY 249
Cdd:cd03294  177 VDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDY 256

nikE

PRK10419

nickel ABC transporter ATP-binding protein NikE;

4-237

3.24e-54

nickel ABC transporter ATP-binding protein NikE;

Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 178.34 E-value: 3.24e-54

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAA-----GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIL 78
Cdd:PRK10419   2 TLLNVSGLSHHYAHGGlsgkhQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESP----SQGNVSWRGEPLA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDERMQAFRwSEMSMVFQSAMNALNPvlpmEEQFCDVI---MRH-TNMTREQARKRAEGLLEIVDIHPSRLTDYPHQF 154
Cdd:PRK10419  78 KLNRAQRKAFR-RDIQMVFQDSISAVNP----RKTVREIIrepLRHlLSLDKAERLARASEMLRAVDLDDSVLDKRPPQL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:PRK10419 153 SGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVE 232


                 ...
gi 694160455 235 VAP 237
Cdd:PRK10419 233 TQP 235

CcmA

COG1131

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

6-244

6.12e-53

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 173.71 E-value: 6.12e-53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENIlnyS 81
Cdd:COG1131    1 IEVRGLTKRY----GDKTALDGVSLTVEPGEIFGLLGPNGAGKTT----TIRmllgLLRP----TSGEVRVLGEDV---A 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQAFRwsEMSMVFQsamnalNPVLPME---EQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPsRLTDYPHQFSGGM 158
Cdd:COG1131   66 RDPAEVRR--RIGYVPQ------EPALYPDltvRENLRFFARLYGLPRKEARERIDELLELFGLTD-AADRKVGTLSGGM 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPS 238
Cdd:COG1131  137 KQRLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTP 215


                 ....*.
gi 694160455 239 KQILES 244
Cdd:COG1131  216 DELKAR 221

LolD

COG1136

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

3-234

1.57e-52

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 172.54 E-value: 1.57e-52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENIL 78
Cdd:COG1136    2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKST----LLNilggLDRP----TSGEVLIDGQDIS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDERMQAFRWSEMSMVFQS-----AMNAL-NPVLPmeeqfcdviMRHTNMTREQARKRAEGLLEIVDIhPSRLTDYPH 152
Cdd:COG1136   74 SLSERELARLRRRHIGFVFQFfnllpELTALeNVALP---------LLLAGVSRKERRERARELLERVGL-GDRLDHRPS 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMvEFSDRIGIMYSGEL 232
Cdd:COG1136  144 QLSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELA-ARADRVIRLRDGRI 222


                 ..
gi 694160455 233 IE 234
Cdd:COG1136  223 VS 224

phnK

PRK11701

phosphonate C-P lyase system protein PhnK; Provisional

1-256

2.15e-52

phosphonate C-P lyase system protein PhnK; Provisional

Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 173.19 E-value: 2.15e-52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVaFSLMRLHKPPafiTGGEVIFNGE----- 75
Cdd:PRK11701   2 MDQPLLSVRGLTKLY----GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTL-LNALSARLAP---DAGEVHYRMRdgqlr 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  76 NILNYSDERMQAFRWSEMSMVFQSAMNALNPVLP----MEEQFCDVIMRHTNMTREQARKraegLLEIVDIHPSRLTDYP 151
Cdd:PRK11701  74 DLYALSEAERRRLLRTEWGFVHQHPRDGLRMQVSaggnIGERLMAVGARHYGDIRATAGD----WLERVEIDAARIDDLP 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGE 231
Cdd:PRK11701 150 TTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGR 229

                        250       260
                 ....*....|....*....|....*
gi 694160455 232 LIEVAPSKQILESPYHPYTKGLGSS 256
Cdd:PRK11701 230 VVESGLTDQVLDDPQHPYTQLLVSS 254

TauB

COG1116

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...

1-227

4.58e-52

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 172.20 E-value: 4.58e-52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGEN 76
Cdd:COG1116    3 AAAPALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKST----LLRliagLEKP----TSGEVLVDGKP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  77 ILNYSDERmqafrwsemSMVFQSA-----MNAL-NPVLPMEEQfcdvimrhtNMTREQARKRAEGLLEIVDihpsrLTD- 149
Cdd:COG1116   75 VTGPGPDR---------GVVFQEPallpwLTVLdNVALGLELR---------GVPKAERRERARELLELVG-----LAGf 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 150 ---YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVqREILQK-IYALKEEFGFSILFITHDLSLMVEFSDRIG 225
Cdd:COG1116  132 edaYPHQLSGGMRQRVAIARALANDPEVLLMDEPFGALDALT-RERLQDeLLRLWQETGKTVLFVTHDVDEAVFLADRVV 210


                 ..
gi 694160455 226 IM 227
Cdd:COG1116  211 VL 212

ABC_Org_Solvent_Resistant

cd03261

ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...

6-251

1.12e-51

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 170.38 E-value: 1.12e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERM 85
Cdd:cd03261    1 IELRGLTKSF----GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRP----DSGEVLIDGEDISGLSEAEL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQSamNAL--------NPVLPMEEqfcdvimrHTNMTREQARKRAEGLLEIVDIHPSRlTDYPHQFSGG 157
Cdd:cd03261   73 YRLR-RRMGMLFQS--GALfdsltvfeNVAFPLRE--------HTRLSEEEIREIVLEKLEAVGLRGAE-DLYPAELSGG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAP 237
Cdd:cd03261  141 MKKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGT 220

                        250
                 ....*....|....
gi 694160455 238 SKQILESPyHPYTK 251
Cdd:cd03261  221 PEELRASD-DPLVR 233

EcfA2

COG1122

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...

6-243

1.23e-51

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];

Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 170.21 E-value: 1.23e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDERM 85
Cdd:COG1122    1 IELENLSFSY---PGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKP----TSGEVLVDGKDI---TKKNL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQsamnalNPvlpmEEQFC------DVI--MRHTNMTREQARKRAEGLLEIVDihpsrLTDY----PHQ 153
Cdd:COG1122   71 RELR-RKVGLVFQ------NP----DDQLFaptveeDVAfgPENLGLPREEIRERVEEALELVG-----LEHLadrpPHE 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:COG1122  135 LSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIV 213

                        250
                 ....*....|
gi 694160455 234 EVAPSKQILE 243
Cdd:COG1122  214 ADGTPREVFS 223

SapF

COG4167

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

4-253

1.78e-51

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 171.17 E-value: 1.78e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAAG-----DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENiL 78
Cdd:COG4167    3 ALLEVRNLSKTFKYRTGlfrrqQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEP----TSGEILINGHK-L 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDERmqaFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGM 158
Cdd:COG4167   78 EYGDYK---YRCKHIRMIFQDPNTSLNPRLNIGQILEEPLRLNTDLTAEEREERIFATLRLVGLLPEHANFYPHMLSSGQ 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPS 238
Cdd:COG4167  155 KQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKT 234

                        250
                 ....*....|....*
gi 694160455 239 KQILESPYHPYTKGL 253
Cdd:COG4167  235 AEVFANPQHEVTKRL 249

AbcC

COG1135

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

6-253

2.41e-50

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 170.26 E-value: 2.41e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENILNYS 81
Cdd:COG1135    2 IELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKST----LIRcinlLERP----TSGSVLVDGVDLTALS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQAFRwSEMSMVFQSAmNAL-------NPVLPMEeqfcdvimrHTNMTREQARKRAEGLLEIVDihpsrLTD----Y 150
Cdd:COG1135   74 ERELRAAR-RKIGMIFQHF-NLLssrtvaeNVALPLE---------IAGVPKAEIRKRVAELLELVG-----LSDkadaY 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 151 PHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSG 230
Cdd:COG1135  138 PSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENG 217

                        250       260
                 ....*....|....*....|...
gi 694160455 231 ELIEVAPSKQILESPYHPYTKGL 253
Cdd:COG1135  218 RIVEQGPVLDVFANPQSELTRRF 240

CP_lyasePhnK

TIGR02323

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...

3-256

4.93e-49

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]

Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 164.23 E-value: 4.93e-49

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    3 APLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRlHKPPafiTGGEVIFNGEN-----I 77
Cdd:TIGR02323   1 KPLLQVSGLSKSY----GGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAG-RLAP---DHGTATYIMRSgaeleL 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   78 LNYSD-ERMQAFRwSEMSMVFQSAMNALNPVLP----MEEQFCDVIMRHTNMTREQARKraegLLEIVDIHPSRLTDYPH 152
Cdd:TIGR02323  73 YQLSEaERRRLMR-TEWGFVHQNPRDGLRMRVSaganIGERLMAIGARHYGNIRATAQD----WLEEVEIDPTRIDDLPR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:TIGR02323 148 AFSGGMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRV 227

                         250       260
                  ....*....|....*....|....
gi 694160455  233 IEVAPSKQILESPYHPYTKGLGSS 256
Cdd:TIGR02323 228 VESGLTDQVLDDPQHPYTQLLVSS 251

ABC_NrtD_SsuB_transporters

cd03293

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...

6-227

7.76e-49

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 162.64 E-value: 7.76e-49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENILNYS 81
Cdd:cd03293    1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKST----LLRiiagLERP----TSGEVLVDGEPVTGPG 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERmqafrwsemSMVFQSA-----MNAL-NPVLPMEEQfcdvimrhtNMTREQARKRAEGLLEIVDihpsrLTD----YP 151
Cdd:cd03293   73 PDR---------GYVFQQDallpwLTVLdNVALGLELQ---------GVPKAEARERAEELLELVG-----LSGfenaYP 129

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 152 HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVqREILQK-IYALKEEFGFSILFITHDLSLMVEFSDRIGIM 227
Cdd:cd03293  130 HQLSGGMRQRVALARALAVDPDVLLLDEPFSALDALT-REQLQEeLLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205

PotA

COG3842

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...

1-245

3.26e-48

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 165.27 E-value: 3.26e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRL---HKPPafiTGGEVIFNGENI 77
Cdd:COG3842    1 MAMPALELENVSKRY----GDVTALDDVSLSIEPGEFVALLGPSGCGKTT----LLRMiagFETP---DSGRILLDGRDV 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  78 LNYSDERmqafRwsEMSMVFQS-A----MNAL-NpvlpmeeqfcdvIM---RHTNMTREQARKRAEGLLEIVdihpsRLT 148
Cdd:COG3842   70 TGLPPEK----R--NVGMVFQDyAlfphLTVAeN------------VAfglRMRGVPKAEIRARVAELLELV-----GLE 126

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 149 D----YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHD----LSLmvef 220
Cdd:COG3842  127 GladrYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDqeeaLAL---- 202

                        250       260
                 ....*....|....*....|....*
gi 694160455 221 SDRIGIMYSGELIEVAPSKQILESP 245
Cdd:COG3842  203 ADRIAVMNDGRIEQVGTPEEIYERP 227

ABC_cobalt_CbiO_domain1

cd03225

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...

7-231

4.84e-48

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 160.33 E-value: 4.84e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   7 SIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDERMQ 86
Cdd:cd03225    1 ELKNLSFSY--PDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGP----TSGEVLVDGKDL---TKLSLK 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  87 AFRWsEMSMVFQsamnalNPvlpmEEQFC------DVI--MRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGM 158
Cdd:cd03225   72 ELRR-KVGLVFQ------NP----DDQFFgptveeEVAfgLENLGLPEEEIEERVEEALELVGLE-GLRDRSPFTLSGGQ 139

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGE 231
Cdd:cd03225  140 KQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211

GlnQ

COG1126

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...

5-251

5.21e-48

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 161.32 E-value: 5.21e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlNYSDER 84
Cdd:COG1126    1 MIEIENLHKSF----GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEP----DSGTITVDGEDL-TDSKKD 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwSEMSMVFQSA-----MNALNPVlpMEEQfcdviMRHTNMTREQARKRAEGLLEIVDIhPSRLTDYPHQFSGGMR 159
Cdd:COG1126   72 INKLR-RKVGMVFQQFnlfphLTVLENV--TLAP-----IKVKKMSKAEAEERAMELLERVGL-ADKADAYPAQLSGGQQ 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 160 QRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSK 239
Cdd:COG1126  143 QRVAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPE 221

                        250
                 ....*....|..
gi 694160455 240 QILESPYHPYTK 251
Cdd:COG1126  222 EFFENPQHERTR 233

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

2-253

2.36e-47

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 166.80 E-value: 2.36e-47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   2 TAPLISIRNLCVDYITAAGDVR-------ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLhkppaFITGGEVIFNG 74
Cdd:PRK15134 272 ASPLLDVEQLQVAFPIRKGILKrtvdhnvVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRL-----INSQGEIWFDG 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  75 ENILNYSDERMQAFRwSEMSMVFQSAMNALNPVLPMEEQFCDVI-MRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQ 153
Cdd:PRK15134 347 QPLHNLNRRQLLPVR-HRIQVVFQDPNSSLNPRLNVLQIIEEGLrVHQPTLSAAQREQQVIAVMEEVGLDPETRHRYPAE 425

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:PRK15134 426 FSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVV 505

                        250       260
                 ....*....|....*....|
gi 694160455 234 EVAPSKQILESPYHPYTKGL 253
Cdd:PRK15134 506 EQGDCERVFAAPQQEYTRQL 525

proV

TIGR01186

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...

18-251

5.27e-47

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 162.33 E-value: 5.27e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   18 AAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFRWSEMSMVF 97
Cdd:TIGR01186   2 KTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEP----TAGQIFIDGENIMKQSPVELREVRRKKIGMVF 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   98 QSAmnALNPVLPMEEQfCDVIMRHTNMTREQARKRAEGLLEIVDIhPSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIM 177
Cdd:TIGR01186  78 QQF--ALFPHMTILQN-TSLGPELLGWPEQERKEKALELLKLVGL-EEYEHRYPDELSGGMQQRVGLARALAAEPDILLM 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455  178 DEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPYTK 251
Cdd:TIGR01186 154 DEAFSALDPLIRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVE 227

ABC_MetN_methionine_transporter

cd03258

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...

5-245

6.51e-47

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 158.13 E-value: 6.51e-47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENILNY 80
Cdd:cd03258    1 MIELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKST----LIRcingLERP----TSGSVLVDGTDLTLL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFRwSEMSMVFQ-----SAMNAL-NPVLPMEeqfcdvimrHTNMTREQARKRAEGLLEIVDihpsrLTD----Y 150
Cdd:cd03258   73 SGKELRKAR-RRIGMIFQhfnllSSRTVFeNVALPLE---------IAGVPKAEIEERVLELLELVG-----LEDkadaY 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 151 PHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSG 230
Cdd:cd03258  138 PAQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKG 217

                        250
                 ....*....|....*
gi 694160455 231 ELIEVAPSKQILESP 245
Cdd:cd03258  218 EVVEEGTVEEVFANP 232

ABC_Carb_Solutes_like

cd03259

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...

6-236

2.14e-45

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 153.44 E-value: 2.14e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERm 85
Cdd:cd03259    1 LELKGLSKTY----GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERP----DSGEILIDGRDVTGVPPER- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 qafRwsEMSMVFQSAmnALNPVLPMEE--QFCdviMRHTNMTREQARKRAEGLLEIVDIHPsRLTDYPHQFSGGMRQRLV 163
Cdd:cd03259   72 ---R--NIGMVFQDY--ALFPHLTVAEniAFG---LKLRGVPKAEIRARVRELLELVGLEG-LLNRYPHELSGGQQQRVA 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:cd03259  141 LARALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213

ABC_OpuCA_Osmoprotection

cd03295

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...

6-245

5.93e-45

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 153.61 E-value: 5.93e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERM 85
Cdd:cd03295    1 IEFENVTKRY---GGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEP----TSGEIFIDGEDIREQDPVEL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QafrwSEMSMVFQSAmnALNPVLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTD-YPHQFSGGMRQRLVI 164
Cdd:cd03295   74 R----RKIGYVIQQI--GLFPHMTVEENI-ALVPKLLKWPKEKIRERADELLALVGLDPAEFADrYPHELSGGQQQRVGV 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 165 AIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILES 244
Cdd:cd03295  147 ARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRS 226


                 .
gi 694160455 245 P 245
Cdd:cd03295  227 P 227

ProV

COG4175

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...

18-245

9.21e-45

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 156.80 E-value: 9.21e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  18 AAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFRWSEMSMVF 97
Cdd:COG4175   36 KTGQTVGVNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEP----TAGEVLIDGEDITKLSKKELRELRRKKMSMVF 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  98 QSAmnALNP---VL-----PMEEQfcdvimrhtNMTREQARKRAEGLLEIVDihpsrLTD----YPHQFSGGMRQRLVIA 165
Cdd:COG4175  112 QHF--ALLPhrtVLenvafGLEIQ---------GVPKAERRERAREALELVG-----LAGwedsYPDELSGGMQQRVGLA 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 166 IALALNPKMIIMDEPTTALDVVV----QREILQkiyaLKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQI 241
Cdd:COG4175  176 RALATDPDILLMDEAFSALDPLIrremQDELLE----LQAKLKKTIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEI 251


                 ....
gi 694160455 242 LESP 245
Cdd:COG4175  252 LTNP 255

FepC

COG1120

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...

5-242

3.99e-43

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];

Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 149.04 E-value: 3.99e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSder 84
Cdd:COG1120    1 MLEAENLSVGY----GGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKP----SSGEVLLDGRDLASLS--- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 mQAFRWSEMSMVFQSAMNALN-PVLpmeeqfcDVIMR----HTNMTR---EQARKRAEGLLEIVDIHPSRLTDYpHQFSG 156
Cdd:COG1120   70 -RRELARRIAYVPQEPPAPFGlTVR-------ELVALgrypHLGLFGrpsAEDREAVEEALERTGLEHLADRPV-DELSG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:COG1120  141 GERQRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQG 220


                 ....*.
gi 694160455 237 PSKQIL 242
Cdd:COG1120  221 PPEEVL 226

metN

PRK11153

DL-methionine transporter ATP-binding subunit; Provisional

6-251

9.39e-43

DL-methionine transporter ATP-binding subunit; Provisional

Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 150.72 E-value: 9.39e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERM 85
Cdd:PRK11153   2 IELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERP----TSGRVLVDGQDLTALSEKEL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQ-----SAMNAL-NPVLPMEEQfcdvimrhtNMTREQARKRAEGLLEIVDihpsrLTD----YPHQFS 155
Cdd:PRK11153  78 RKAR-RQIGMIFQhfnllSSRTVFdNVALPLELA---------GTPKAEIKARVTELLELVG-----LSDkadrYPAQLS 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 156 GGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEV 235
Cdd:PRK11153 143 GGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQ 222

                        250
                 ....*....|....*.
gi 694160455 236 APSKQILESPYHPYTK 251
Cdd:PRK11153 223 GTVSEVFSHPKHPLTR 238

ABC_PstB_phosphate_transporter

cd03260

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...

6-241

1.01e-42

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).

Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 147.33 E-value: 1.01e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHK-PPAFITGGEVIFNGENILNYSDER 84
Cdd:cd03260    1 IELRDLNVYY----GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlIPGAPDEGEVLLDGKDIYDLDVDV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwsEMSMVFQSAmnalnPVLPMEeqfcdvIMR--------HTNMTREQARKRAEGLLEIVDIHPS---RLTdyPHQ 153
Cdd:cd03260   77 LELRR--RVGMVFQKP-----NPFPGS------IYDnvayglrlHGIKLKEELDERVEEALRKAALWDEvkdRLH--ALG 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03260  142 LSGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLV 219


                 ....*...
gi 694160455 234 EVAPSKQI 241
Cdd:cd03260  220 EFGPTEQI 227

ABC_DR_subfamily_A

cd03230

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...

6-232

1.91e-42

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 144.46 E-value: 1.91e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENILNYS 81
Cdd:cd03230    1 IEVRNLSKRY----GKKTALDDISLTVEKGEIYGLLGPNGAGKTT----LIKiilgLLKP----DSGEIKVLGKDIKKEP 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQafrwsEMSMVFQSAMNalnpvlpmeeqfcdvimrHTNMTreqarkraegLLEIVDihpsrltdyphqFSGGMRQR 161
Cdd:cd03230   69 EEVKR-----RIGYLPEEPSL------------------YENLT----------VRENLK------------LSGGMKQR 103

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:cd03230  104 LALAQALLHDPELLILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173

ABC_Class3

cd03229

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...

6-231

5.53e-42

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 143.48 E-value: 5.53e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERm 85
Cdd:cd03229    1 LELKNVSKRY----GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEP----DSGSILIDGEDLTDLEDEL- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRWSeMSMVFQSAmnALNPvlpmeeqfcdvimrhtNMTREQarKRAEGLleivdihpsrltdyphqfSGGMRQRLVIA 165
Cdd:cd03229   72 PPLRRR-IGMVFQDF--ALFP----------------HLTVLE--NIALGL------------------SGGQQQRVALA 112

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 166 IALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGE 231
Cdd:cd03229  113 RALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178

CysA

COG1118

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...

6-250

1.98e-40

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 144.52 E-value: 1.98e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENIlnYS 81
Cdd:COG1118    3 IEVRNISKRF----GSFTLLDDVSLEIASGELVALLGPSGSGKTT----LLRiiagLETP----DSGRIVLNGRDL--FT 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 D----ERMQAFrwsemsmVFQSAmnALnpvlpmeeqfcdviMRHtnMT---------------REQARKRAEGLLEIVDI 142
Cdd:COG1118   69 NlpprERRVGF-------VFQHY--AL--------------FPH--MTvaeniafglrvrppsKAEIRARVEELLELVQL 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 143 hpSRLTD-YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFS 221
Cdd:COG1118  124 --EGLADrYPSQLSGGQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELA 201

                        250       260
                 ....*....|....*....|....*....
gi 694160455 222 DRIGIMYSGELIEVAPSKQILESPYHPYT 250
Cdd:COG1118  202 DRVVVMNQGRIEQVGTPDEVYDRPATPFV 230

ABC_HisP_GlnQ

cd03262

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...

6-232

3.65e-40

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.

Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 139.97 E-value: 3.65e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNySDERM 85
Cdd:cd03262    1 IEIKNLHKSF----GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEP----DSGTIIIDGLKLTD-DKKNI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQS-----AMNALNPVL--PMEEQfcdvimrhtNMTREQARKRAEGLLEIVDIhPSRLTDYPHQFSGGM 158
Cdd:cd03262   72 NELR-QKVGMVFQQfnlfpHLTVLENITlaPIKVK---------GMSKAEAEERALELLEKVGL-ADKADAYPAQLSGGQ 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:cd03262  141 QQRVAIARALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213

OpuBA

COG1125

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...

6-245

5.75e-40

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 142.15 E-value: 5.75e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafSL-M--RLHKPpafiTGGEVIFNGENILNYSD 82
Cdd:COG1125    2 IEFENVTKRY---PDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTT---TLrMinRLIEP----TSGRILIDGEDIRDLDP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 ERMqafRWSeMSMVFQSAmnALNPVLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTD-YPHQFSGGMRQR 161
Cdd:COG1125   72 VEL---RRR-IGYVIQQI--GLFPHMTVAENIA-TVPRLLGWDKERIRARVDELLELVGLDPEEYRDrYPHELSGGQQQR 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVqREILQK-IYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQ 240
Cdd:COG1125  145 VGVARALAADPPILLMDEPFGALDPIT-REQLQDeLLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEE 223


                 ....*
gi 694160455 241 ILESP 245
Cdd:COG1125  224 ILANP 228

PstB

COG1117

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...

2-251

7.72e-40

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 140.56 E-value: 7.72e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   2 TAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHK--PPAFITGgEVIFNGENILN 79
Cdd:COG1117    8 LEPKIEVRNLNVYY----GDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDliPGARVEG-EILLDGEDIYD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 ySDERMQAFRwSEMSMVFQSAmnalNPvLPM----------------EEQFCDVIMrhtnmtrEQARKRAeGLLEIV-Di 142
Cdd:COG1117   83 -PDVDVVELR-RRVGMVFQKP----NP-FPKsiydnvayglrlhgikSKSELDEIV-------EESLRKA-ALWDEVkD- 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 143 hpsRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEFSD 222
Cdd:COG1117  147 ---RLKKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD--YTIVIVTHNMQQAARVSD 221

                        250       260
                 ....*....|....*....|....*....
gi 694160455 223 RIGIMYSGELIEVAPSKQILESPYHPYTK 251
Cdd:COG1117  222 YTAFFYLGELVEFGPTEQIFTNPKDKRTE 250

NatA

COG4555

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...

5-243

1.59e-39

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];

Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 139.22 E-value: 1.59e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDER 84
Cdd:COG4555    1 MIEVENLSKKY----GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKP----DSGSILIDGEDVRKEPREA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQafrwsEMSMVFQSamNALNPVLPMEE--QFCDVIMRhtnMTREQARKRAEGLLEIVDihpsrLTDYPHQ----FSGGM 158
Cdd:COG4555   73 RR-----QIGVLPDE--RGLYDRLTVREniRYFAELYG---LFDEELKKRIEELIELLG-----LEEFLDRrvgeLSTGM 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPS 238
Cdd:COG4555  138 KKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSL 216


                 ....*
gi 694160455 239 KQILE 243
Cdd:COG4555  217 DELRE 221

YbbA

COG4181

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...

1-238

2.66e-39

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 138.34 E-value: 2.66e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGEN 76
Cdd:COG4181    4 SSAPIIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKST----LLGllagLDRP----TSGTVRLAGQD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  77 ILNYSDERMQAFRWSEMSMVFQS-----AMNAL-NPVLPMEEQfcdvimrhtnmTREQARKRAEGLLEIVDI-HpsRLTD 149
Cdd:COG4181   76 LFALDEDARARLRARHVGFVFQSfqllpTLTALeNVMLPLELA-----------GRRDARARARALLERVGLgH--RLDH 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 150 YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLmVEFSDRIGIMYS 229
Cdd:COG4181  143 YPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPAL-AARCDRVLRLRA 221


                 ....*....
gi 694160455 230 GELIEVAPS 238
Cdd:COG4181  222 GRLVEDTAA 230

ABC_Iron-Siderophores_B12_Hemin

cd03214

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...

7-233

7.42e-39

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.

Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 135.64 E-value: 7.42e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   7 SIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSdermq 86
Cdd:cd03214    1 EVENLSVGY----GGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKP----SSGEILLDGKDLASLS----- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  87 afrwsemsmvfqsamnalnpvlpmeeqfcdvimrhtnmTREQARKRA--EGLLEIVDIhpSRLTDYP-HQFSGGMRQRLV 163
Cdd:cd03214   68 --------------------------------------PKELARKIAyvPQALELLGL--AHLADRPfNELSGGERQRVL 107

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03214  108 LARALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIV 177

ABC_PotA_N

cd03300

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...

6-245

9.05e-39

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 136.98 E-value: 9.05e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLHKPPAFITGGEVIFNGENILNYSDERM 85
Cdd:cd03300    1 IELENVSKFY----GGFVALDGVSLDIKEGEFFTLLGPSGCGKTT----LLRLIAGFETPTSGEILLDGKDITNLPPHKR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QafrwseMSMVFQSAmnALNPVLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIVDI--HPSRltdYPHQFSGGMRQRLV 163
Cdd:cd03300   73 P------VNTVFQNY--ALFPHLTVFENIA-FGLRLKKLPKAEIKERVAEALDLVQLegYANR---KPSQLSGGQQQRVA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILE 243
Cdd:cd03300  141 IARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYE 220


                 ..
gi 694160455 244 SP 245
Cdd:cd03300  221 EP 222

PRK15112

peptide ABC transporter ATP-binding protein SapF;

5-256

1.74e-38

peptide ABC transporter ATP-binding protein SapF;

Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 137.23 E-value: 1.74e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAG-----DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENiLN 79
Cdd:PRK15112   4 LLEVRNLSKTFRYRTGwfrrqTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEP----TSGELLIDDHP-LH 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 YSDermQAFRWSEMSMVFQSAMNALNPVLPMEeQFCDVIMR-HTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGM 158
Cdd:PRK15112  79 FGD---YSYRSQRIRMIFQDPSTSLNPRQRIS-QILDFPLRlNTDLEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQ 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPS 238
Cdd:PRK15112 155 KQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGST 234

                        250
                 ....*....|....*...
gi 694160455 239 KQILESPYHPYTKGLGSS 256
Cdd:PRK15112 235 ADVLASPLHELTKRLIAG 252

PRK14239

phosphate transporter ATP-binding protein; Provisional

1-250

2.46e-38

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 136.44 E-value: 2.46e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHK-PPAFITGGEVIFNGENIln 79
Cdd:PRK14239   1 MTEPILQVSDLSVYY----NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDlNPEVTITGSIVYNGHNI-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 YSDERMQAFRWSEMSMVFQSAmnalNPvLPMEeQFCDVI--MR----HTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQ 153
Cdd:PRK14239  75 YSPRTDTVDLRKEIGMVFQQP----NP-FPMS-IYENVVygLRlkgiKDKQVLDEAVEKSLKGASIWDEVKDRLHDSALG 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:PRK14239 149 LSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD--YTMLLVTRSMQQASRISDRTGFFLDGDLI 226

                        250
                 ....*....|....*..
gi 694160455 234 EVAPSKQILESPYHPYT 250
Cdd:PRK14239 227 EYNDTKQMFMNPKHKET 243

LolD_lipo_ex

TIGR02211

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...

5-234

6.41e-38

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 134.40 E-value: 6.41e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDER 84
Cdd:TIGR02211   1 LLKCENLGKRYQEGKLDTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNP----TSGEVLFNGQSLSKLSSNE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   85 MQAFRWSEMSMVFQ-----SAMNAL-NPVLPMeeqfcdVImrhTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGM 158
Cdd:TIGR02211  77 RAKLRNKKLGFIYQfhhllPDFTALeNVAMPL------LI---GKKSVKEAKERAYEMLEKVGLE-HRINHRPSELSGGE 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455  159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFsDRIGIMYSGELIE 234
Cdd:TIGR02211 147 RQRVAIARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKL-DRVLEMKDGQLFN 221

ABC_ATPase

cd00267

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...

7-231

1.63e-37

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 131.21 E-value: 1.63e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   7 SIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQ 86
Cdd:cd00267    1 EIENLSFRY----GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKP----TSGEILIDGKDIAKLPLEELR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  87 afrwSEMSMVFQsamnalnpvlpmeeqfcdvimrhtnmtreqarkraeglleivdihpsrltdyphqFSGGMRQRLVIAI 166
Cdd:cd00267   73 ----RRIGYVPQ-------------------------------------------------------LSGGQRQRVALAR 93

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 167 ALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGE 231
Cdd:cd00267   94 ALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157

ZnuC

COG1121

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...

1-245

2.83e-37

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 133.29 E-value: 2.83e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlny 80
Cdd:COG1121    2 MMMPAIELENLTVSY----GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPP----TSGTVRLFGKPP--- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 sdermqAFRWSEMSMVFQSAmnALNPVLPM--EeqfcDVIM----RHTNMTR---EQARKRAEGLLEIVDihpsrLTDYP 151
Cdd:COG1121   71 ------RRARRRIGYVPQRA--EVDWDFPItvR----DVVLmgryGRRGLFRrpsRADREAVDEALERVG-----LEDLA 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 H----QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIgIM 227
Cdd:COG1121  134 DrpigELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRV-LL 211

                        250
                 ....*....|....*...
gi 694160455 228 YSGELIEVAPSKQILESP 245
Cdd:COG1121  212 LNRGLVAHGPPEEVLTPE 229

ABC_CysA_sulfate_importer

cd03296

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...

6-249

4.27e-37

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 132.85 E-value: 4.27e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS-DER 84
Cdd:cd03296    3 IEVRNVSKRF----GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERP----DSGTILFGGEDATDVPvQER 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFrwsemsmVFQSAmnALNPVLPMEEQFC---DVIMRHTNMTREQARKRAEGLLEIVDIhpSRLTD-YPHQFSGGMRQ 160
Cdd:cd03296   75 NVGF-------VFQHY--ALFRHMTVFDNVAfglRVKPRSERPPEAEIRAKVHELLKLVQL--DWLADrYPAQLSGGQRQ 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 161 RLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQ 240
Cdd:cd03296  144 RVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDE 223


                 ....*....
gi 694160455 241 ILESPYHPY 249
Cdd:cd03296  224 VYDHPASPF 232

ABC_DrrA

cd03265

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...

6-235

1.46e-36

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 130.95 E-value: 1.46e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDErm 85
Cdd:cd03265    1 IEVENLVKKY----GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKP----TSGRATVAGHDVVREPRE-- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 qaFRWSeMSMVFQSAmnALNPVLPMEEQFcdVIM-RHTNMTREQARKRAEGLLEIVDihpsrLTDYPHQ----FSGGMRQ 160
Cdd:cd03265   71 --VRRR-IGIVFQDL--SVDDELTGWENL--YIHaRLYGVPGAERRERIDELLDFVG-----LLEAADRlvktYSGGMRR 138

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 161 RLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEV 235
Cdd:cd03265  139 RLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAE 213

ABC_PhnC_transporter

cd03256

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...

6-233

3.85e-36

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 130.38 E-value: 3.85e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERM 85
Cdd:cd03256    1 IEVENLSKTY---PNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEP----TSGSVLIDGTDINKLKGKAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQ--------SAM-NALNPVLPmeeqfcdvimRHT------NMTREQARKRAEGLLEIVDI--HPSRLT 148
Cdd:cd03256   74 RQLR-RQIGMIFQqfnlierlSVLeNVLSGRLG----------RRStwrslfGLFPKEEKQRALAALERVGLldKAYQRA 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 149 DyphQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMY 228
Cdd:cd03256  143 D---QLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLK 219


                 ....*
gi 694160455 229 SGELI 233
Cdd:cd03256  220 DGRIV 224

ABC_Mj1267_LivG_branched

cd03219

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...

6-245

5.31e-36

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).

Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 129.86 E-value: 5.31e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILnysdeRM 85
Cdd:cd03219    1 LEVRGLTKRF----GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRP----TSGSVLFDGEDIT-----GL 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRWSEMSMV--FQ-----SAMNALNPVL--PMEEQFCDVIMRHTNMTREQARKRAEGLLEIVdihpsRLTDYPHQ--- 153
Cdd:cd03219   68 PPHEIARLGIGrtFQiprlfPELTVLENVMvaAQARTGSGLLLARARREEREARERAEELLERV-----GLADLADRpag 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 -FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKeEFGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:cd03219  143 eLSYGQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELR-ERGITVLLVEHDMDVVMSLADRVTVLDQGRV 221

                        250
                 ....*....|...
gi 694160455 233 IEVAPSKQILESP 245
Cdd:cd03219  222 IAEGTPDEVRNNP 234

ABC_subfamily_A

cd03263

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...

6-233

7.35e-36

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.

Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 129.16 E-value: 7.35e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVaFSLMR-LHKPpafiTGGEVIFNGENILNysdER 84
Cdd:cd03263    1 LQIRNLTKTYKK--GTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTT-LKMLTgELRP----TSGTAYINGYSIRT---DR 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwsEMSMVFQSamNALNPVLPMEEQ---FCdvIMRHTNmtREQARKRAEGLLEIVDIHPSRlTDYPHQFSGGMRQR 161
Cdd:cd03263   71 KAARQ--SLGYCPQF--DALFDELTVREHlrfYA--RLKGLP--KSEIKEEVELLLRVLGLTDKA-NKRARTLSGGMKRK 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03263  142 LSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLR 211

drrA

TIGR01188

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...

20-233

1.38e-35

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]

Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 130.59 E-value: 1.38e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQafrwsEMSMVFQS 99
Cdd:TIGR01188   4 GDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRP----TSGTARVAGYDVVREPRKVRR-----SIGIVPQY 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  100 AmnALNPVLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIVDIHPSRlTDYPHQFSGGMRQRLVIAIALALNPKMIIMDE 179
Cdd:TIGR01188  75 A--SVDEDLTGRENL-EMMGRLYGLPKDEAEERAEELLELFELGEAA-DRPVGTYSGGMRRRLDIAASLIHQPDVLFLDE 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 694160455  180 PTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:TIGR01188 151 PTTGLDPRTRRAIWDYIRALKEE-GVTILLTTHYMEEADKLCDRIAIIDHGRII 203

3a0106s01

TIGR00968

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]

20-249

2.95e-35

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]

Pssm-ID: 130041 [Multi-domain] Cd Length: 237 Bit Score: 127.99 E-value: 2.95e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERmqafrwSEMSMVFQS 99
Cdd:TIGR00968  11 GSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQP----DSGRIRLNGQDATRVHARD------RKIGFVFQH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  100 AmnALNPVLPMEEQ--FCDVIMRHTnmtREQARKRAEGLLEIVDIhpSRLTD-YPHQFSGGMRQRLVIAIALALNPKMII 176
Cdd:TIGR00968  81 Y--ALFKHLTVRDNiaFGLEIRKHP---KAKIKARVEELLELVQL--EGLGDrYPNQLSGGQRQRVALARALAVEPQVLL 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455  177 MDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPY 249
Cdd:TIGR00968 154 LDEPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPF 226

SunT

COG2274

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...

6-243

3.81e-35

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 134.96 E-value: 3.81e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSderM 85
Cdd:COG2274  474 IELENVSFRY--PGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEP----TSGRILIDGIDLRQID---P 544

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQsamnalNPVLpmeeqFCDVI-----MRHTNMTREQARKRAE--GLLEIVDIHP----SRLTDYPHQF 154
Cdd:COG2274  545 ASLR-RQIGVVLQ------DVFL-----FSGTIrenitLGDPDATDEEIIEAARlaGLHDFIEALPmgydTVVGEGGSNL 612

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGELIE 234
Cdd:COG2274  613 SGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHRLS-TIRLADRIIVLDKGRIVE 689


                 ....*....
gi 694160455 235 VAPSKQILE 243
Cdd:COG2274  690 DGTHEELLA 698

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

6-233

4.52e-35

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 125.23 E-value: 4.52e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENILNYS 81
Cdd:cd03216    1 LELRGITKRF----GGVKALDGVSLSVRRGEVHALLGENGAGKST----LMKilsgLYKP----DSGEILVDGKEVSFAS 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQAFRwseMSMVfqsamnalnpvlpmeeqfcdvimrhtnmtreqarkraeglleivdihpsrltdypHQFSGGMRQR 161
Cdd:cd03216   69 PRDARRAG---IAMV-------------------------------------------------------YQLSVGERQM 90

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03216   91 VEIARALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161

PhnT2

TIGR03265

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...

3-249

6.11e-35

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 130.16 E-value: 6.11e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    3 APLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENIL 78
Cdd:TIGR03265   2 SPYLSIDNIRKRF----GAFTALKDISLSVKKGEFVCLLGPSGCGKTT----LLRiiagLERQ----TAGTIYQGGRDIT 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   79 NYSDERmqafrwSEMSMVFQSAmnALNPVLPMEEqfcDVIMRHTN--MTREQARKRAEGLLEIVDIhPSRLTDYPHQFSG 156
Cdd:TIGR03265  70 RLPPQK------RDYGIVFQSY--ALFPNLTVAD---NIAYGLKNrgMGRAEVAERVAELLDLVGL-PGSERKYPGQLSG 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:TIGR03265 138 GQQQRVALARALATSPGLLLLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVG 217

                         250
                  ....*....|...
gi 694160455  237 PSKQILESPYHPY 249
Cdd:TIGR03265 218 TPQEIYRHPATPF 230

MalK

COG3839

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...

6-245

1.17e-34

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];

Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 129.42 E-value: 1.17e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENILNYS 81
Cdd:COG3839    4 LELENVSKSY----GGVEALKDIDLDIEDGEFLVLLGPSGCGKST----LLRmiagLEDP----TSGEILIGGRDVTDLP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 -DERMqafrwseMSMVFQSAmnALNP---V-----LPMEeqfcdviMRhtNMTREQARKRAEGLLEIVDIHPsRLTDYPH 152
Cdd:COG3839   72 pKDRN-------IAMVFQSY--ALYPhmtVyeniaFPLK-------LR--KVPKAEIDRRVREAAELLGLED-LLDRKPK 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLslmVE---FSDRIGIMYS 229
Cdd:COG3839  133 QLSGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQ---VEamtLADRIAVMND 209

                        250
                 ....*....|....*.
gi 694160455 230 GELIEVAPSKQILESP 245
Cdd:COG3839  210 GRIQQVGTPEELYDRP 225

nikD

PRK10418

nickel transporter ATP-binding protein NikD; Provisional

6-253

1.20e-34

nickel transporter ATP-binding protein NikD; Provisional

Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 126.74 E-value: 1.20e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVdyitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFITGGEVIFNGENILnysderM 85
Cdd:PRK10418   5 IELRNIAL-----QAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAGVRQTAGRVLLDGKPVA------P 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRWSEMSMVFQSAMNALNPVLPMEE---QFCDVIMRHTNMTREQARKRAEGLLEivdihPSRLTD-YPHQFSGGMRQR 161
Cdd:PRK10418  74 CALRGRKIATIMQNPRSAFNPLHTMHTharETCLALGKPADDATLTAALEAVGLEN-----AARVLKlYPFEMSGGMLQR 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQI 241
Cdd:PRK10418 149 MMIALALLCEAPFIIADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETL 228

                        250
                 ....*....|..
gi 694160455 242 LESPYHPYTKGL 253
Cdd:PRK10418 229 FNAPKHAVTRSL 240

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

26-182

1.74e-34

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 123.14 E-value: 1.74e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDERMQAFRwSEMSMVFQSamNALN 105
Cdd:pfam00005   2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSP----TEGTILLDGQDL---TDDERKSLR-KEIGYVFQD--PQLF 71

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455  106 PVLPMEEQFCDVIMRHTNMTREQARKRAEGL--LEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTT 182
Cdd:pfam00005  72 PRLTVRENLRLGLLLKGLSKREKDARAEEALekLGLGDLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

PRK14267

phosphate ABC transporter ATP-binding protein; Provisional

6-251

1.83e-34

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 126.50 E-value: 1.83e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHK--PPAFITGgEVIFNGENILNYSDE 83
Cdd:PRK14267   5 IETVNLRVYY----GSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLElnEEARVEG-EVRLFGRNIYSPDVD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RMQAFRwsEMSMVFQSAmnalNPVLPM---EEQFCDVIMRHTNMTREQARKRAEGLLE---IVDIHPSRLTDYPHQFSGG 157
Cdd:PRK14267  80 PIEVRR--EVGMVFQYP----NPFPHLtiyDNVAIGVKLNGLVKSKKELDERVEWALKkaaLWDEVKDRLNDYPSNLSGG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEFSDRIGIMYSGELIEVAP 237
Cdd:PRK14267 154 QRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE--YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGP 231

                        250
                 ....*....|....
gi 694160455 238 SKQILESPYHPYTK 251
Cdd:PRK14267 232 TRKVFENPEHELTE 245

cbiO

PRK13635

energy-coupling factor ABC transporter ATP-binding protein;

1-271

3.15e-34

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 126.28 E-value: 3.15e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYITAagDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPA-FITGGEVIFNGENILn 79
Cdd:PRK13635   1 MKEEIIRVEHISFRYPDA--ATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAgTITVGGMVLSEETVW- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 ysDERMQafrwseMSMVFQsamnalNPvlpmEEQFC------DVIMRHTN--MTREQARKRAEGLLEIVDIHpSRLTDYP 151
Cdd:PRK13635  78 --DVRRQ------VGMVFQ------NP----DNQFVgatvqdDVAFGLENigVPREEMVERVDQALRQVGME-DFLNREP 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSlMVEFSDRIGIMYSGE 231
Cdd:PRK13635 139 HRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLD-EAAQADRVIVMNKGE 217

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 694160455 232 LIEVAPSKQILESPYHPYTKGLGSSFPPLTGPKTKLTGIP 271
Cdd:PRK13635 218 ILEEGTPEEIFKSGHMLQEIGLDVPFSVKLKELLKRNGIL 257

ABCC_MRP_Like

cd03228

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...

6-231

3.76e-34

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 122.88 E-value: 3.76e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERm 85
Cdd:cd03228    1 IEFKNVSFSYPG--RPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDP----TSGEILIDGVDLRDLDLES- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 qafRWSEMSMVFQsamnalNPVLpmeeqFCDVImrhtnmtreqarkrAEGLLeivdihpsrltdyphqfSGGMRQRLVIA 165
Cdd:cd03228   74 ---LRKNIAYVPQ------DPFL-----FSGTI--------------RENIL-----------------SGGQRQRIAIA 108

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 166 IALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGE 231
Cdd:cd03228  109 RALLRDPPILILDEATSALDPETEALILEALRALAK--GKTVIVIAHRLS-TIRDADRIIVLDDGR 171

heterocyst_DevA

TIGR02982

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...

6-232

6.71e-34

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.

Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 123.98 E-value: 6.71e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    6 ISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVaFSLM-RLHKPPAfitgGEVIFNGENILNYSDER 84
Cdd:TIGR02982   2 ISIRNLNHYYGHGSLRKQVLFDINLEINPGEIVILTGPSGSGKTTL-LTLIgGLRSVQE----GSLKVLGQELHGASKKQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   85 MQAFRWSeMSMVFQsAMNALnPVLPMEEqfcDVIMR---HTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQR 161
Cdd:TIGR02982  77 LVQLRRR-IGYIFQ-AHNLL-GFLTARQ---NVQMAlelQPNLSYQEARERARAMLEAVGLG-DHLNYYPHNLSGGQKQR 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455  162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDlSLMVEFSDRIGIMYSGEL 232
Cdd:TIGR02982 150 VAIARALVHHPKLVLADEPTAALDSKSGRDVVELMQKLAKEQGCTILMVTHD-NRILDVADRILQMEDGKL 219

CydD

COG4988

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...

2-244

3.45e-33

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 128.72 E-value: 3.45e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   2 TAPLISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS 81
Cdd:COG4988  333 GPPSIELEDVSFSY---PGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPP----YSGSILINGVDLSDLD 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 dermQAFRWSEMSMVFQsamnalNPVLpmeeqFCDVI-----MRHTNMTRE---QARKRAeGLLEIVDIHP----SRLTD 149
Cdd:COG4988  406 ----PASWRRQIAWVPQ------NPYL-----FAGTIrenlrLGRPDASDEeleAALEAA-GLDEFVAALPdgldTPLGE 469

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 150 YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSLMVEFsDRIGIMYS 229
Cdd:COG4988  470 GGRGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRLALLAQA-DRILVLDD 546

                        250
                 ....*....|....*
gi 694160455 230 GELIEVAPSKQILES 244
Cdd:COG4988  547 GRIVEQGTHEELLAK 561

glnQ

PRK09493

glutamine ABC transporter ATP-binding protein GlnQ;

20-245

4.52e-33

glutamine ABC transporter ATP-binding protein GlnQ;

Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 122.51 E-value: 4.52e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafITGGEVIFNGENIL-NYSDERMqaFRwSEMSMVFQ 98
Cdd:PRK09493  12 GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEE----ITSGDLIVDGLKVNdPKVDERL--IR-QEAGMVFQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  99 S-----AMNALNPVLpmeeqFCDVIMRhtNMTREQARKRAEGLLEIVDIhPSRLTDYPHQFSGGMRQRLVIAIALALNPK 173
Cdd:PRK09493  85 QfylfpHLTALENVM-----FGPLRVR--GASKEEAEKQARELLAKVGL-AERAHHYPSELSGGQQQRVAIARALAVKPK 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 694160455 174 MIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:PRK09493 157 LMLFDEPTSALDPELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNP 227

FtsE

COG2884

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

6-237

5.10e-33

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 121.70 E-value: 5.10e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGE-VFgLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDER 84
Cdd:COG2884    2 IRFENVSKRY---PGGREALSDVSLEIEKGEfVF-LTGPSGAGKSTLLKLLYGEERP----TSGQVLVNGQDLSRLKRRE 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwSEMSMVFQ-----SAMNAL-NPVLPMEEqfcdvimrhTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGM 158
Cdd:COG2884   74 IPYLR-RRIGVVFQdfrllPDRTVYeNVALPLRV---------TGKSRKEIRRRVREVLDLVGLS-DKAKALPHELSGGE 142

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAP 237
Cdd:COG2884  143 QQRVAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEINRR-GTTVLIATHDLELVDRMPKRVLELEDGRLVRDEA 220

ABC_ModC_like

cd03299

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...

6-245

1.08e-32

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 121.29 E-value: 1.08e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRAcNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERM 85
Cdd:cd03299    1 LKVENLSKDW----KEFKL-KNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKP----DSGKILLNGKDITNLPPEKR 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QafrwseMSMVFQSamNALNPVLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIVDIhpSRLTD-YPHQFSGGMRQRLVI 164
Cdd:cd03299   72 D------ISYVPQN--YALFPHMTVYKNI-AYGLKKRKVDKKEIERKVLEIAEMLGI--DHLLNrKPETLSGGEQQRVAI 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 165 AIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILES 244
Cdd:cd03299  141 ARALVVNPKILLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKK 220


                 .
gi 694160455 245 P 245
Cdd:cd03299  221 P 221

PRK10070

proline/glycine betaine ABC transporter ATP-binding protein ProV;

27-251

2.06e-32

proline/glycine betaine ABC transporter ATP-binding protein ProV;

Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 124.38 E-value: 2.06e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFRWSEMSMVFQSAmnALNP 106
Cdd:PRK10070  46 DASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEP----TRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSF--ALMP 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 107 VLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDV 186
Cdd:PRK10070 120 HMTVLDNTA-FGMELAGINAEERREKALDALRQVGLE-NYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDP 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 187 VVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPYTK 251
Cdd:PRK10070 198 LIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVR 262

FetA

COG4619

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

6-232

1.41e-31

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 117.61 E-value: 1.41e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSderM 85
Cdd:COG4619    1 LELEGLSFRV----GGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPP----TSGEIYLDGKPLSAMP---P 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQsamnalNPVL---PMEEQFCDV-IMRHTNMTREQARKraegLLEIVDIHPSRLTDYPHQFSGGMRQR 161
Cdd:COG4619   70 PEWR-RQVAYVPQ------EPALwggTVRDNLPFPfQLRERKFDRERALE----LLERLGLPPDILDKPVERLSGGERQR 138

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:COG4619  139 LALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

2-241

9.19e-31

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 120.89 E-value: 9.19e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   2 TAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGE-- 75
Cdd:COG1129    1 AEPLLEMRGISKSF----GGVKALDGVSLELRPGEVHALLGENGAGKST----LMKilsgVYQP----DSGEILLDGEpv 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  76 NILNYSDERMQAfrwseMSMVFQSamnaLNPV----------LPMEeqfcdvIMRHTNMTREQARKRAEGLLEIV--DIH 143
Cdd:COG1129   69 RFRSPRDAQAAG-----IAIIHQE----LNLVpnlsvaenifLGRE------PRRGGLIDWRAMRRRARELLARLglDID 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 144 PSRLTDyphQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDvvvQREI---LQKIYALKEEfGFSILFITHDLSLMVEF 220
Cdd:COG1129  134 PDTPVG---DLSVAQQQLVEIARALSRDARVLILDEPTASLT---EREVerlFRIIRRLKAQ-GVAIIYISHRLDEVFEI 206

                        250       260
                 ....*....|....*....|.
gi 694160455 221 SDRIGIMYSGELIEVAPSKQI 241
Cdd:COG1129  207 ADRVTVLRDGRLVGTGPVAEL 227

potA

TIGR01187

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...

40-245

1.02e-30

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 118.37 E-value: 1.02e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   40 LAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENILNYSDERmqafrwSEMSMVFQSAmnALNPVLPMEEQFCdVIM 119
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDS----GSIMLDGEDVTNVPPHL------RHINMVFQSY--ALFPHMTVEENVA-FGL 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  120 RHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYAL 199
Cdd:TIGR01187  68 KMRKVPRAEIKPRVLEALRLVQLE-EFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTI 146

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 694160455  200 KEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:TIGR01187 147 QEQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEP 192

ABC_cobalt_CbiO_domain2

cd03226

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...

7-233

1.21e-30

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 115.05 E-value: 1.21e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   7 SIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnysderMQ 86
Cdd:cd03226    1 RIENISFSY---KKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKE----SSGSILLNGKPI-------KA 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  87 AFRWSEMSMVfqsaMNALNPVLPMEEQFCDVIMRHTNMTREQARkrAEGLLEivDIHPSRLTD-YPHQFSGGMRQRLVIA 165
Cdd:cd03226   67 KERRKSIGYV----MQDVDYQLFTDSVREELLLGLKELDAGNEQ--AETVLK--DLDLYALKErHPLSLSGGQKQRLAIA 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 166 IALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03226  139 AALLSGKDLLIFDEPTSGLDYKNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205

CydC

COG4987

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...

2-243

2.39e-30

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 120.64 E-value: 2.39e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   2 TAPLISIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS 81
Cdd:COG4987  330 GGPSLELEDVSFRY--PGAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDP----QSGSITLGGVDLRDLD 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERmqafRWSEMSMVFQSA-------MNAL---NPVLPmEEQFCDVImrhtnmtrEQArkraeGLLEIVDIHP----SRL 147
Cdd:COG4987  404 EDD----LRRRIAVVPQRPhlfdttlRENLrlaRPDAT-DEELWAAL--------ERV-----GLGDWLAALPdgldTWL 465

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 148 TDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSLMvEFSDRIGIM 227
Cdd:COG4987  466 GEGGRRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALA--GRTVLLITHRLAGL-ERMDRILVL 542

                        250
                 ....*....|....*.
gi 694160455 228 YSGELIEVAPSKQILE 243
Cdd:COG4987  543 EDGRIVEQGTHEELLA 558

ABC_ModC_molybdenum_transporter

cd03297

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...

27-233

3.53e-30

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 113.93 E-value: 3.53e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIaPGEVFGLAGESGCGKSTVAFSLMRLHKPPA--FITGGEVIFNGENILNYSDERMQafrwseMSMVFQSAmnAL 104
Cdd:cd03297   16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGgtIVLNGTVLFDSRKKINLPPQQRK------IGLVFQQY--AL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 105 NPVLPMEEQFCDVIMRHTNMTReqaRKRAEGLLEIVDIHPsRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTAL 184
Cdd:cd03297   87 FPHLNVRENLAFGLKRKRNRED---RISVDELLDLLGLDH-LLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSAL 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 694160455 185 DVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03297  163 DRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQ 211

ntrCD

TIGR01184

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...

27-246

6.85e-30

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]

Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 113.71 E-value: 6.85e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFR------WSEMSMVFQSA 100
Cdd:TIGR01184   3 GVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQP----TSGGVILEGKQITEPGPDRMVVFQnysllpWLTVRENIALA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  101 MNALNPVLPMEEQFcDVIMRHTNMT--REQARKRaeglleivdihpsrltdyPHQFSGGMRQRLVIAIALALNPKMIIMD 178
Cdd:TIGR01184  79 VDRVLPDLSKSERR-AIVEEHIALVglTEAADKR------------------PGQLSGGMKQRVAIARALSIRPKVLLLD 139

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455  179 EPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVApskQILESPY 246
Cdd:TIGR01184 140 EPFGALDALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIG---QILEVPF 204

ABC_ATP_SaoA

NF040729

ABC transporter ATP-binding protein SaoA; SaoA is the ATP-binding subunit of an ABC ...

6-227

8.43e-30

Pssm-ID: 468693 [Multi-domain] Cd Length: 248 Bit Score: 114.07 E-value: 8.43e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERm 85
Cdd:NF040729   2 LKIQNISKTFINNKKENEVLKDISFDVEEGEFVSLLGPSGCGKTTLLTIIAGFQNA----TSGEILVNGNEVTKPGPDR- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 qAFrwsemsmVFQSAmnALNPVLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIvdihpSRLTD----YPHQFSGGMRQR 161
Cdd:NF040729  77 -GF-------VFQNY--ALFPWMTVKENI-EYPMKQQKMPKQEREKRLNELLEM-----AQLTGkenlYPHQISGGMKQR 140

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVqREILQK-IYALKEEFGFSILFITHDLSLMVEFSDRIGIM 227
Cdd:NF040729 141 TAVIRALACKPEVLLMDEPLGAVDFQM-RQILQEeLESIWLKDKTTVLMVTHDVDEAVYLSDRVIVM 206

ABC_MalK_N

cd03301

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...

6-236

9.77e-30

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.

Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 112.73 E-value: 9.77e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILN-YSDER 84
Cdd:cd03301    1 VELENVTKRF----GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEP----TSGRIYIGGRDVTDlPPKDR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 mqafrwsEMSMVFQS-----AMNAL-NPVLPMEeqfcdviMRHtnMTREQARKRAEGLLEIVDIhpSRLTD-YPHQFSGG 157
Cdd:cd03301   73 -------DIAMVFQNyalypHMTVYdNIAFGLK-------LRK--VPKDEIDERVREVAELLQI--EHLLDrKPKQLSGG 134

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:cd03301  135 QRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213

potG

PRK11607

putrescine ABC transporter ATP-binding subunit PotG;

1-251

1.21e-29

putrescine ABC transporter ATP-binding subunit PotG;

Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 116.47 E-value: 1.21e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLcvdyiTAAGD-VRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIln 79
Cdd:PRK11607  15 ALTPLLEIRNL-----TKSFDgQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQP----TAGQIMLDGVDL-- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 ysdERMQAFRwSEMSMVFQSAmnALNPVLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIVdiHPSRLTDY-PHQFSGGM 158
Cdd:PRK11607  84 ---SHVPPYQ-RPINMMFQSY--ALFPHMTVEQNIA-FGLKQDKLPKAEIASRVNEMLGLV--HMQEFAKRkPHQLSGGQ 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPS 238
Cdd:PRK11607 155 RQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEP 234

                        250
                 ....*....|...
gi 694160455 239 KQILEspyHPYTK 251
Cdd:PRK11607 235 EEIYE---HPTTR 244

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

4-243

1.27e-29

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 118.37 E-value: 1.27e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    4 PLISIRNLCVDYITAA-GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFN-GENILNYS 81
Cdd:TIGR03269 278 PIIKVRNVSKRYISVDrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEP----TSGEVNVRvGDEWVDMT 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   82 ----DERMQAFRWseMSMVFQSAmnALNPVLPMEEQFCDVImrHTNMTREQARKRAEGLLEIV----DIHPSRLTDYPHQ 153
Cdd:TIGR03269 354 kpgpDGRGRAKRY--IGILHQEY--DLYPHRTVLDNLTEAI--GLELPDELARMKAVITLKMVgfdeEKAEEILDKYPDE 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:TIGR03269 428 LSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIV 507

                         250
                  ....*....|
gi 694160455  234 EVAPSKQILE 243
Cdd:TIGR03269 508 KIGDPEEIVE 517

ABC_Metallic_Cations

cd03235

ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...

7-224

2.56e-29

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.

Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 111.47 E-value: 2.56e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   7 SIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNysdermq 86
Cdd:cd03235    1 EVEDLTVSY----GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKP----TSGSIRVFGKPLEK------- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  87 afRWSEMSMVFQSAmnALNPVLPME-EQFcdVIM---RHTNMTR---EQARKRAEGLLEIVDihpsrLTDYPH----QFS 155
Cdd:cd03235   66 --ERKRIGYVPQRR--SIDRDFPISvRDV--VLMglyGHKGLFRrlsKADKAKVDEALERVG-----LSELADrqigELS 134

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 156 GGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRI 224
Cdd:cd03235  135 GGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRV 202

ABC_BcrA_bacitracin_resist

cd03268

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...

6-234

2.95e-29

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.

Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 111.15 E-value: 2.95e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDErm 85
Cdd:cd03268    1 LKTNDLTKTY----GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKP----DSGEITFDGKSYQKNIEA-- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 qafrWSEMSMVFQSAmnALNPVLPMEEQFcdviMRHTNMTREQaRKRAEGLLEIVDihpsrLTDYPH----QFSGGMRQR 161
Cdd:cd03268   71 ----LRRIGALIEAP--GFYPNLTARENL----RLLARLLGIR-KKRIDEVLDVVG-----LKDSAKkkvkGFSLGMKQR 134

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:cd03268  135 LGIALALLGNPDLLILDEPTNGLDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKLIE 206

fbpC

PRK11432

ferric ABC transporter ATP-binding protein;

20-245

4.56e-29

ferric ABC transporter ATP-binding protein;

Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 114.43 E-value: 4.56e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERmqafrwSEMSMVFQS 99
Cdd:PRK11432  17 GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKP----TEGQIFIDGEDVTHRSIQQ------RDICMVFQS 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 AmnALNPVLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIVDI--HPSRLTDyphQFSGGMRQRLVIAIALALNPKMIIM 177
Cdd:PRK11432  87 Y--ALFPHMSLGENV-GYGLKMLGVPKEERKQRVKEALELVDLagFEDRYVD---QISGGQQQRVALARALILKPKVLLF 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 178 DEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:PRK11432 161 DEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQP 228

PRK10851

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

20-245

7.95e-29

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 113.64 E-value: 7.95e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLHKPPAFITGGEVIFNGENIlnysdERMQAfRWSEMSMVFQS 99
Cdd:PRK10851  13 GRTQVLNDISLDIPSGQMVALLGPSGSGKTT----LLRIIAGLEHQTSGHIRFHGTDV-----SRLHA-RDRKVGFVFQH 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 -----AMNALN------PVLPmeeqfcdvimRHTNMTREQARKRAEGLLEIVDIhpSRLTD-YPHQFSGGMRQRLVIAIA 167
Cdd:PRK10851  83 yalfrHMTVFDniafglTVLP----------RRERPNAAAIKAKVTQLLEMVQL--AHLADrYPAQLSGGQKQRVALARA 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 168 LALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:PRK10851 151 LAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREP 228

ABC_putative_ATPase

cd03269

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...

20-233

8.08e-29

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 110.06 E-value: 8.08e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDERMQAFRWsemsmvfqs 99
Cdd:cd03269   11 GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILP----DSGEVLFDGKPL---DIAARNRIGY--------- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 amnalnpvLPME------EQFCDVIM---RHTNMTREQARKRAEGLLEIVDIHP---SRLtdypHQFSGGMRQRLVIAIA 167
Cdd:cd03269   75 --------LPEErglypkMKVIDQLVylaQLKGLKKEEARRRIDEWLERLELSEyanKRV----EELSKGNQQKVQFIAA 142

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 168 LALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03269  143 VIHDPELLILDEPFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAV 207

PRK13633

energy-coupling factor transporter ATPase;

5-261

1.08e-28

energy-coupling factor transporter ATPase;

Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 111.72 E-value: 1.08e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVR--ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNG---ENILN 79
Cdd:PRK13633   4 MIKCKNVSYKYESNEESTEklALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIP----SEGKVYVDGldtSDEEN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 YSDERMQAfrwsemSMVFQSAMNALNPVLpMEEqfcDVIMRHTNM--TREQARKRAEGLLEIVDIHPSRltDY-PHQFSG 156
Cdd:PRK13633  80 LWDIRNKA------GMVFQNPDNQIVATI-VEE---DVAFGPENLgiPPEEIRERVDESLKKVGMYEYR--RHaPHLLSG 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEfSDRIGIMYSGELIEVA 236
Cdd:PRK13633 148 GQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEG 226

                        250       260
                 ....*....|....*....|....*
gi 694160455 237 PSKQILesPYHPYTKGLGSSFPPLT 261
Cdd:PRK13633 227 TPKEIF--KEVEMMKKIGLDVPQVT 249

PRK11264

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

26-257

1.18e-28

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 111.00 E-value: 1.18e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPA-FITGGEVIFNGENILNYSDERMQAFRwSEMSMVFQSaMNaL 104
Cdd:PRK11264  20 HGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAgTIRVGDITIDTARSLSQQKGLIRQLR-QHVGFVFQN-FN-L 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 105 NPVLPMEEQFCD--VIMRhtNMTREQARKRAEGLLEIVDIhPSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTT 182
Cdd:PRK11264  97 FPHRTVLENIIEgpVIVK--GEPKEEATARARELLAKVGL-AGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTS 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 183 ALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPYTKGLGSSF 257
Cdd:PRK11264 174 ALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQPRTRQFLEKF 247

TauB

COG4525

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

4-213

1.21e-28

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 111.11 E-value: 1.21e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVaFSLMRLHKPPafiTGGEVIFNGENILNYSDE 83
Cdd:COG4525    2 SMLTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTL-LNLIAGFLAP---SSGEITLDGVPVTGPGAD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RmqafrwsemSMVFQSamNALNPVLpmeeqfcDVI------MRHTNMTREQARKRAEGLLEIVDihpsrLTDY----PHQ 153
Cdd:COG4525   78 R---------GVVFQK--DALLPWL-------NVLdnvafgLRLRGVPKAERRARAEELLALVG-----LADFarrrIWQ 134

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVqREILQK-IYALKEEFGFSILFITHD 213
Cdd:COG4525  135 LSGGMRQRVGIARALAADPRFLLMDEPFGALDALT-REQMQElLLDVWQRTGKGVFLITHS 194

PRK14271

phosphate ABC transporter ATP-binding protein; Provisional

3-250

1.53e-28

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 111.34 E-value: 1.53e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVDYitaAGDVrACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLH-KPPAFITGGEVIFNGENILNYS 81
Cdd:PRK14271  19 APAMAAVNLTLGF---AGKT-VLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNdKVSGYRYSGDVLLGGRSIFNYR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DerMQAFRwSEMSMVFQSAmnalNPvLPME--EQFCDVIMRHTNMTREQARKRAEGLLEIV---DIHPSRLTDYPHQFSG 156
Cdd:PRK14271  95 D--VLEFR-RRVGMLFQRP----NP-FPMSimDNVLAGVRAHKLVPRKEFRGVAQARLTEVglwDAVKDRLSDSPFRLSG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEFSDRIGIMYSGELIEVA 236
Cdd:PRK14271 167 GQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEG 244

                        250
                 ....*....|....
gi 694160455 237 PSKQILESPYHPYT 250
Cdd:PRK14271 245 PTEQLFSSPKHAET 258

YhaQ

COG4152

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

20-233

2.06e-28

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 111.35 E-value: 2.06e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITG------GEVIFNGENiLNYSD---------ER 84
Cdd:COG4152   12 GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTT----TIRI------ILGilapdsGEVLWDGEP-LDPEDrrrigylpeER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 mqafrwsemsmvfqsamnALNPVLPMEEQfcdvIM---RHTNMTREQARKRAEGLLEIVDIhPSRLTDYPHQFSGGMRQR 161
Cdd:COG4152   81 ------------------GLYPKMKVGEQ----LVylaRLKGLSKAEAKRRADEWLERLGL-GDRANKKVEELSKGNQQK 137

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:COG4152  138 VQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKV 208

cbiO

PRK13637

energy-coupling factor transporter ATPase;

6-241

3.82e-28

energy-coupling factor transporter ATPase;

Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 110.52 E-value: 3.82e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLcvDYITAAG---DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENI----L 78
Cdd:PRK13637   3 IKIENL--THIYMEGtpfEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKP----TSGKIIIDGVDItdkkV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDERmqafrwSEMSMVFQsamnalnpvLPMEEQFCDVIM-------RHTNMTREQARKRAEGLLEIVDIHPSRLTD-Y 150
Cdd:PRK13637  77 KLSDIR------KKVGLVFQ---------YPEYQLFEETIEkdiafgpINLGLSEEEIENRVKRAMNIVGLDYEDYKDkS 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 151 PHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSG 230
Cdd:PRK13637 142 PFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKG 221

                        250
                 ....*....|.
gi 694160455 231 ELIEVAPSKQI 241
Cdd:PRK13637 222 KCELQGTPREV 232

cbiO

PRK13639

cobalt transporter ATP-binding subunit; Provisional

5-245

6.63e-28

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 109.40 E-value: 6.63e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlNYSDER 84
Cdd:PRK13639   1 ILETRDLKYSY---PDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKP----TSGEVLIKGEPI-KYDKKS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwSEMSMVFQSAMNALnpVLPMEEQfcDVIMRHTNM--TREQARKRAEGLLEIVDihpsrLTDY----PHQFSGGM 158
Cdd:PRK13639  73 LLEVR-KTVGIVFQNPDDQL--FAPTVEE--DVAFGPLNLglSKEEVEKRVKEALKAVG-----MEGFenkpPHHLSGGQ 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPS 238
Cdd:PRK13639 143 KKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTP 221


                 ....*..
gi 694160455 239 KQILESP 245
Cdd:PRK13639 222 KEVFSDI 228

ABC_NatA_sodium_exporter

cd03266

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...

5-233

1.46e-27

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.

Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 107.07 E-value: 1.46e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGeniLNYSDER 84
Cdd:cd03266    1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEP----DAGFATVDG---FDVVKEP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwsemSMVFQSAMNALNPVLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIVDIHPsrLTDYP-HQFSGGMRQRLV 163
Cdd:cd03266   74 AEARR----RLGFVSDSTGLYDRLTARENL-EYFAGLYGLKGDELTARLEELADRLGMEE--LLDRRvGGFSTGMRQKVA 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03266  147 IARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRAL-GKCILFSTHIMQEVERLCDRVVVLHRGRVV 215

PhnT

TIGR03258

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...

26-245

2.09e-27

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.

Pssm-ID: 132302 [Multi-domain] Cd Length: 362 Bit Score: 110.08 E-value: 2.09e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFItgGEVIFNGENILNYSDERmqafrwSEMSMVFQSAmnALN 105
Cdd:TIGR03258  22 DDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAGLT--GRIAIADRDLTHAPPHK------RGLALLFQNY--ALF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  106 PVLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIVdihpsRLTD----YPHQFSGGMRQRLVIAIALALNPKMIIMDEPT 181
Cdd:TIGR03258  92 PHLKVEDNVA-FGLRAQKMPKADIAERVADALKLV-----GLGDaaahLPAQLSGGMQQRIAIARAIAIEPDVLLLDEPL 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455  182 TALDVVVQREILQKIYALKEEF-GFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:TIGR03258 166 SALDANIRANMREEIAALHEELpELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAP 230

ABC_FtsE

cd03292

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...

20-232

2.52e-27

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages

Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 106.34 E-value: 2.52e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFRWSeMSMVFQS 99
Cdd:cd03292   12 NGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELP----TSGTIRVNGQDVSDLRGRAIPYLRRK-IGVVFQD 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 amnalNPVLPMEEQFCDVI--MRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIM 177
Cdd:cd03292   87 -----FRLLPDRNVYENVAfaLEVTGVPPREIRKRVPAALELVGLS-HKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 178 DEPTTALDVVVQREI---LQKIYALkeefGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:cd03292  161 DEPTGNLDPDTTWEImnlLKKINKA----GTTVVVATHAKELVDTTRHRVIALERGKL 214

ABC_TM1139_LivF_branched

cd03224

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...

6-243

3.99e-27

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.

Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 105.98 E-value: 3.99e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNY-SDER 84
Cdd:cd03224    1 LEVENLNAGY----GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPP----RSGSIRFDGRDITGLpPHER 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAfrwsEMSMVFQSamNALNPVLPMEEQFcdvIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMRQRLVI 164
Cdd:cd03224   73 ARA----GIGYVPEG--RRIFPELTVEENL---LLGAYARRRAKRKARLERVYELFPRLKERRKQLAGTLSGGEQQMLAI 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 165 AIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILE 243
Cdd:cd03224  144 ARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLA 221

potA

PRK09452

spermidine/putrescine ABC transporter ATP-binding protein PotA;

1-245

4.65e-27

spermidine/putrescine ABC transporter ATP-binding protein PotA;

Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 109.27 E-value: 4.65e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNY 80
Cdd:PRK09452  10 SLSPLVELRGISKSF----DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETP----DSGRIMLDGQDITHV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQafrwseMSMVFQSAmnALNPVLPMeeqFCDVI--MRHTNMTREQARKRAEGLLEIVdihpsRLTDY----PHQF 154
Cdd:PRK09452  82 PAENRH------VNTVFQSY--ALFPHMTV---FENVAfgLRMQKTPAAEITPRVMEALRMV-----QLEEFaqrkPHQL 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:PRK09452 146 SGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQ 225

                        250
                 ....*....|.
gi 694160455 235 VAPSKQILESP 245
Cdd:PRK09452 226 DGTPREIYEEP 236

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

1-240

6.59e-27

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 110.12 E-value: 6.59e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGE- 75
Cdd:COG3845    1 MMPPALELRGITKRF----GGVVANDDVSLTVRPGEIHALLGENGAGKST----LMKilygLYQP----DSGEILIDGKp 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  76 -NILNYSDermqAFRwSEMSMVFQS-----AMNAL-NPVLPMEEQFCDVImrhtnmTREQARKRAEGLLEI--VDIHPSR 146
Cdd:COG3845   69 vRIRSPRD----AIA-LGIGMVHQHfmlvpNLTVAeNIVLGLEPTKGGRL------DRKAARARIRELSERygLDVDPDA 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 147 LTdypHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGI 226
Cdd:COG3845  138 KV---EDLSVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTV 213

                        250
                 ....*....|....
gi 694160455 227 MYSGELIEVAPSKQ 240
Cdd:COG3845  214 LRRGKVVGTVDTAE 227

CcmA

COG4133

ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...

4-224

6.63e-27

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 104.87 E-value: 6.63e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPpafiTGGEVIFNGENIln 79
Cdd:COG4133    1 MMLEAENLSCRR----GERLLFSGLSFTLAAGEALALTGPNGSGKTT----LLRilagLLPP----SAGEVLWNGEPI-- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 ysDERMQAFRwSEMSMVFQSamNALNPVLPMEEQ---FCDviMRHTNMTREqarkRAEGLLEIVDIHPsRLTDYPHQFSG 156
Cdd:COG4133   67 --RDAREDYR-RRLAYLGHA--DGLKPELTVRENlrfWAA--LYGLRADRE----AIDEALEAVGLAG-LADLPVRQLSA 134

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLsLMVEFSDRI 224
Cdd:COG4133  135 GQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLAR-GGAVLLTTHQP-LELAAARVL 200

ABC_drug_resistance_like

cd03264

ABC-type multidrug transport system, ATPase component; The biological function of this family ...

6-233

1.05e-26

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 104.58 E-value: 1.05e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGeVFGLAGESGCGKSTvafsLMRL---HKPPafiTGGEVIFNGENILNYSD 82
Cdd:cd03264    1 LQLENLTKRY----GKKRALDGVSLTLGPG-MYGLLGPNGAGKTT----LMRIlatLTPP---SSGTIRIDGQDVLKQPQ 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 E--RM-----QAFRWSemsmvfqsamnalnPVLPMEEqFCDVIMRHTNMTREQARKRAEGLLEIVDIHPsRLTDYPHQFS 155
Cdd:cd03264   69 KlrRRigylpQEFGVY--------------PNFTVRE-FLDYIAWLKGIPSKEVKARVDEVLELVNLGD-RAKKKIGSLS 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 156 GGMRQRLVIAIALALNPKMIIMDEPTTALDV---VVQREILQKIYALKeefgfSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:cd03264  133 GGMRRRVGIAQALVGDPSILIVDEPTAGLDPeerIRFRNLLSELGEDR-----IVILSTHIVEDVESLCNQVAVLNKGKL 207


                 .
gi 694160455 233 I 233
Cdd:cd03264  208 V 208

cbiO

PRK13642

energy-coupling factor transporter ATPase;

5-239

1.32e-26

energy-coupling factor transporter ATPase;

Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 105.95 E-value: 1.32e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYiTAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAfslmRLhkppafITGGEVIFNGenILNYSDER 84
Cdd:PRK13642   4 ILEVENLVFKY-EKESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTA----RL------IDGLFEEFEG--KVKIDGEL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFR-WS---EMSMVFQSAMNALnpVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRlTDYPHQFSGGMRQ 160
Cdd:PRK13642  71 LTAENvWNlrrKIGMVFQNPDNQF--VGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFK-TREPARLSGGQKQ 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 161 RLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEfSDRIGIMYSGELI-EVAPSK 239
Cdd:PRK13642 148 RVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIkEAAPSE 226

PhnL

COG4778

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...

1-224

1.37e-26

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];

Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 104.82 E-value: 1.37e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTaPLISIRNLCVDY-ITAAGDVR--ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGE-- 75
Cdd:COG4778    1 MT-TLLEVENLSKTFtLHLQGGKRlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLP----DSGSILVRHDgg 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  76 --NILNYSDERMQAFRWSEMSMVFQ--------SAMnalnpvlpmeeqfcDVIM---RHTNMTREQARKRAEGLLEIVDI 142
Cdd:COG4778   76 wvDLAQASPREILALRRRTIGYVSQflrviprvSAL--------------DVVAeplLERGVDREEARARARELLARLNL 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 143 hPSRLTD-YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFS 221
Cdd:COG4778  142 -PERLWDlPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVA 219


                 ...
gi 694160455 222 DRI 224
Cdd:COG4778  220 DRV 222

PRK10619

histidine ABC transporter ATP-binding protein HisP;

28-248

1.42e-26

histidine ABC transporter ATP-binding protein HisP;

Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 105.44 E-value: 1.42e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  28 VSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENI---------LNYSDERMQAFRWSEMSMVFQ 98
Cdd:PRK10619  24 VSLQANAGDVISIIGSSGSGKSTFLRCINFLEKP----SEGSIVVNGQTInlvrdkdgqLKVADKNQLRLLRTRLTMVFQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  99 -----SAMNALNPVLPMEEQFcdvimrhTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALNPK 173
Cdd:PRK10619 100 hfnlwSHMTVLENVMEAPIQV-------LGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARALAMEPE 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 174 MIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHP 248
Cdd:PRK10619 173 VLLFDEPTSALDPELVGEVLRIMQQLAEE-GKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSP 246

LivF

COG0410

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...

3-245

1.55e-26

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];

Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 104.68 E-value: 1.55e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS- 81
Cdd:COG0410    1 MPMLEVENLHAGY----GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPP----RSGSIRFDGEDITGLPp 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQAfrwsEMSMVfqsamnalnpvlpMEEqfcdvimRH--TNMT-----------REQARKRAEGLLEIVDIHPsRLT 148
Cdd:COG0410   73 HRIARL----GIGYV-------------PEG-------RRifPSLTveenlllgayaRRDRAEVRADLERVYELFP-RLK 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 149 DYPHQF----SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRI 224
Cdd:COG0410  128 ERRRQRagtlSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRA 206

                        250       260
                 ....*....|....*....|.
gi 694160455 225 GIMYSGELIEVAPSKQILESP 245
Cdd:COG0410  207 YVLERGRIVLEGTAAELLADP 227

ABC_Carb_Monos_II

cd03215

Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...

3-232

1.61e-26

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 103.28 E-value: 1.61e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVdyitaAGDVRacnNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSD 82
Cdd:cd03215    2 EPVLEVRGLSV-----KGAVR---DVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPP----ASGEITLDGKPVTRRSP 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 ERMQAfrwSEMSMVFQS-AMNALNPVLPMEEqfcdvimrhtNMTreqarkraeglleivdihpsrltdYPHQFSGGMRQR 161
Cdd:cd03215   70 RDAIR---AGIAYVPEDrKREGLVLDLSVAE----------NIA------------------------LSSLLSGGNQQK 112

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:cd03215  113 VVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182

PRK14246

phosphate ABC transporter ATP-binding protein; Provisional

27-251

1.75e-26

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 105.13 E-value: 1.75e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHK--PPAFITGGEVIFNGENILNYSDERMQafrwSEMSMVFQSAmNAL 104
Cdd:PRK14246  28 DITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiyDSKIKVDGKVLYFGKDIFQIDAIKLR----KEVGMVFQQP-NPF 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 105 nPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIV----DIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEP 180
Cdd:PRK14246 103 -PHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVglwkEVY-DRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEP 180

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 181 TTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPYTK 251
Cdd:PRK14246 181 TSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTE 249

lolD

PRK11629

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

1-216

1.90e-26

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 104.51 E-value: 1.90e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNY 80
Cdd:PRK11629   1 MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTP----TSGDVIFNGQPMSKL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFRWSEMSMVFQsamnaLNPVLPMEEQFCDVIMRHT--NMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGM 158
Cdd:PRK11629  77 SSAAKAELRNQKLGFIYQ-----FHHLLPDFTALENVAMPLLigKKKPAEINSRALEMLAAVGLE-HRANHRPSELSGGE 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSL 216
Cdd:PRK11629 151 RQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQL 208

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

3-241

3.90e-26

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 108.19 E-value: 3.90e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVdyiTAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS- 81
Cdd:COG3845  255 EVVLEVENLSV---RDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPP----ASGSIRLDGEDITGLSp 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQA---------FRW---SEMSMvfqsAMNALnpvlpMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTD 149
Cdd:COG3845  328 RERRRLgvayipedrLGRglvPDMSV----AENLI-----LGRYRRPPFSRGGFLDRKAIRAFAEELIEEFDVRTPGPDT 398

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 150 YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLS-LMvEFSDRIGIMY 228
Cdd:COG3845  399 PARSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDA-GAAVLLISEDLDeIL-ALSDRIAVMY 476

                        250
                 ....*....|...
gi 694160455 229 SGELIEVAPSKQI 241
Cdd:COG3845  477 EGRIVGEVPAAEA 489

cbiO

PRK13648

cobalt transporter ATP-binding subunit; Provisional

26-258

7.68e-26

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 103.68 E-value: 7.68e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDERMQAFRwSEMSMVFQsamnalN 105
Cdd:PRK13648  26 KDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKV----KSGEIFYNNQAI---TDDNFEKLR-KHIGIVFQ------N 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 PvlpmEEQFCDVIMR-------------HTNMTREQARkraegLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNP 172
Cdd:PRK13648  92 P----DNQFVGSIVKydvafglenhavpYDEMHRRVSE-----ALKQVDML-ERADYEPNALSGGQKQRVAIAGVLALNP 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 173 KMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEfSDRIGIMYSGELIEVAPSKQILESPYHPYTKG 252
Cdd:PRK13648 162 SVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDHAEELTRIG 240


                 ....*.
gi 694160455 253 LGSSFP 258
Cdd:PRK13648 241 LDLPFP 246

cbiO

PRK13636

cobalt transporter ATP-binding subunit; Provisional

1-244

1.07e-25

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 103.77 E-value: 1.07e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlNY 80
Cdd:PRK13636   1 MEDYILKVEELNYNY---SDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKP----SSGRILFDGKPI-DY 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFRWSeMSMVFQSAMNALNPVLPMEeqfcDVIMRHTNMT--REQARKRAEGLLEIVDIHPsrLTDYP-HQFSGG 157
Cdd:PRK13636  73 SRKGLMKLRES-VGMVFQDPDNQLFSASVYQ----DVSFGAVNLKlpEDEVRKRVDNALKRTGIEH--LKDKPtHCLSFG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELI---- 233
Cdd:PRK13636 146 QKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVIlqgn 225

                        250
                 ....*....|...
gi 694160455 234 --EVAPSKQILES 244
Cdd:PRK13636 226 pkEVFAEKEMLRK 238

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

3-241

1.17e-25

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 106.64 E-value: 1.17e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVDyitaagdvRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGE--NILNY 80
Cdd:COG1129  254 EVVLEVEGLSVG--------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPA----DSGEIRLDGKpvRIRSP 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDermqafrwsemsmvfqsAMNA-------------LNPVLPMEE----QFCDVIMRHTNMTREQARKRAEGLLEIVDIH 143
Cdd:COG1129  322 RD-----------------AIRAgiayvpedrkgegLVLDLSIREnitlASLDRLSRGGLLDRRRERALAEEYIKRLRIK 384

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 144 PSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDR 223
Cdd:COG1129  385 TPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELLGLSDR 463

                        250
                 ....*....|....*...
gi 694160455 224 IGIMYSGELIEVAPSKQI 241
Cdd:COG1129  464 ILVMREGRIVGELDREEA 481

ABCC_MsbA

cd03251

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...

6-234

1.66e-25

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 101.92 E-value: 1.66e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVR-ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSder 84
Cdd:cd03251    1 VEFKNVTFRY---PGDGPpVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDV----DSGRILIDGHDVRDYT--- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwSEMSMVFQsamnalNPVLpmeeqFCDVIMRH-----TNMTREQARK--RAEGLLEIVDIHP----SRLTDYPHQ 153
Cdd:cd03251   71 LASLR-RQIGLVSQ------DVFL-----FNDTVAENiaygrPGATREEVEEaaRAANAHEFIMELPegydTVIGERGVK 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGELI 233
Cdd:cd03251  139 LSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLS-TIENADRIVVLEDGKIV 215


                 .
gi 694160455 234 E 234
Cdd:cd03251  216 E 216

modC_ABC

TIGR02142

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...

11-249

1.73e-25

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]

Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 104.42 E-value: 1.73e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   11 LCVDYITAAGDVraCNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPafitGGEVIFNGEnILNYSDERMQ-AFR 89
Cdd:TIGR02142   1 LSARFSKRLGDF--SLDADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPD----EGEIVLNGR-TLFDSRKGIFlPPE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   90 WSEMSMVFQSAmnALNPVLPMEE------QFCDVimrhtnmtrEQARKRAEGLLEIVDIHPsRLTDYPHQFSGGMRQRLV 163
Cdd:TIGR02142  74 KRRIGYVFQEA--RLFPHLSVRGnlrygmKRARP---------SERRISFERVIELLGIGH-LLGRLPGRLSGGEKQRVA 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILE 243
Cdd:TIGR02142 142 IGRALLSSPRLLLMDEPLAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWA 221


                  ....*.
gi 694160455  244 SPYHPY 249
Cdd:TIGR02142 222 SPDLPW 227

cbiO

PRK13652

cobalt transporter ATP-binding subunit; Provisional

5-245

2.41e-25

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 102.57 E-value: 2.41e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDER 84
Cdd:PRK13652   3 LIETRDLCYSY---SGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKP----TSGSVLIRGEPITKENIRE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFrwseMSMVFQSAMNALnpVLPMEEQfcDVIMRHTNM--TREQARKRAEGLLEIVDIHPSRlTDYPHQFSGGMRQRL 162
Cdd:PRK13652  76 VRKF----VGLVFQNPDDQI--FSPTVEQ--DIAFGPINLglDEETVAHRVSSALHMLGLEELR-DRVPHHLSGGEKKRV 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 163 VIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:PRK13652 147 AIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIF 226


                 ...
gi 694160455 243 ESP 245
Cdd:PRK13652 227 LQP 229

PRK14247

phosphate ABC transporter ATP-binding protein; Provisional

6-251

2.72e-25

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 101.91 E-value: 2.72e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHK--PPAFITGgEVIFNGENILNYSDE 83
Cdd:PRK14247   4 IEIRDLKVSF----GQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElyPEARVSG-EVYLDGQDIFKMDVI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RMQafrwSEMSMVFQSAmnalNPVlPMEEQFCDVIM-----RHTNMTRE------QARKRAEGLLEIVDihpsRLTDYPH 152
Cdd:PRK14247  79 ELR----RRVQMVFQIP----NPI-PNLSIFENVALglklnRLVKSKKElqervrWALEKAQLWDEVKD----RLDAPAG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK14247 146 KLSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQI 223

                        250
                 ....*....|....*....
gi 694160455 233 IEVAPSKQILESPYHPYTK 251
Cdd:PRK14247 224 VEWGPTREVFTNPRHELTE 242

cbiO

PRK13632

cobalt transporter ATP-binding subunit; Provisional

4-244

5.19e-25

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 101.61 E-value: 5.19e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDE 83
Cdd:PRK13632   6 VMIKVENVSFSY--PNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKP----QSGEIKIDGITI---SKE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RMQAFRwSEMSMVFQsamnalNPvlpmEEQFC-----DVI---MRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFS 155
Cdd:PRK13632  77 NLKEIR-KKIGIIFQ------NP----DNQFIgatveDDIafgLENKKVPPKKMKDIIDDLAKKVGME-DYLDKEPQNLS 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 156 GGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDlslMVE--FSDRIGIMYSGELI 233
Cdd:PRK13632 145 GGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHD---MDEaiLADKVIVFSEGKLI 221

                        250
                 ....*....|....*..
gi 694160455 234 ------EVAPSKQILES 244
Cdd:PRK13632 222 aqgkpkEILNNKEILEK 238

MdlB

COG1132

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

6-234

5.64e-25

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 105.25 E-value: 5.64e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDERM 85
Cdd:COG1132  340 IEFENVSFSY---PGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDP----TSGRILIDGVDI---RDLTL 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQ-------SAMNAL---NPVLPMEEqfcdVimrhtnmtrEQARKRAeGLLEIVDIHPSRLtDYP---- 151
Cdd:COG1132  410 ESLR-RQIGVVPQdtflfsgTIRENIrygRPDATDEE----V---------EEAAKAA-QAHEFIEALPDGY-DTVvger 473

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 -HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSLmVEFSDRIGIMYSG 230
Cdd:COG1132  474 gVNLSGGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAHRLST-IRNADRILVLDDG 550


                 ....
gi 694160455 231 ELIE 234
Cdd:COG1132  551 RIVE 554

ABCC_ATM1_transporter

cd03253

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...

26-243

6.28e-25

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 100.38 E-value: 6.28e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSderMQAFRwSEMSMVFQsamnalN 105
Cdd:cd03253   18 KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDV----SSGSILIDGQDIREVT---LDSLR-RAIGVVPQ------D 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 PVLpmeeqFCDVIMRHT-----NMTREQARKRAEglleIVDIHPsRLTDYPHQF-----------SGGMRQRLVIAIALA 169
Cdd:cd03253   84 TVL-----FNDTIGYNIrygrpDATDEEVIEAAK----AAQIHD-KIMRFPDGYdtivgerglklSGGEKQRVAIARAIL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 170 LNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSLMVEfSDRIGIMYSGELIEVAPSKQILE 243
Cdd:cd03253  154 KNPPILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEELLA 224

oligo_HPY

TIGR01727

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...

231-317

7.52e-25

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 213647 [Multi-domain] Cd Length: 87 Bit Score: 95.89 E-value: 7.52e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  231 ELIEVAPSKQILESPYHPYTKGLGSSFPPLTGPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEACTKIPTQLKQIEPS 310
Cdd:TIGR01727   1 KIVETGPAEEIFKNPLHPYTKALLSAIPTIKKRDRKLISIPGEVPSLINLPSGCRFYPRCPYAQDECRKEPPALVEIAEG 80


                  ....*..
gi 694160455  311 RFSNCHL 317
Cdd:TIGR01727  81 HRVACHL 87

ArtP

COG4161

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

6-234

1.02e-24

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 100.09 E-value: 1.02e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENI---LNYSD 82
Cdd:COG4161    3 IQLKNINCFY----GSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETP----DSGQLNIAGHQFdfsQKPSE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 ERMQAFRwSEMSMVFQSAmnALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVdihpsRLTD----YPHQFSGGM 158
Cdd:COG4161   75 KAIRLLR-QKVGMVFQQY--NLWPHLTVMENLIEAPCKVLGLSKEQAREKAMKLLARL-----RLTDkadrFPLHLSGGQ 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:COG4161  147 QQRVAIARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQT-GITQVIVTHEVEFARKVASQVVYMEKGRIIE 221

MsbA_lipidA

TIGR02203

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...

5-243

1.29e-24

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]

Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 104.03 E-value: 1.29e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    5 LISIRNLCVDYITAagDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYsdeR 84
Cdd:TIGR02203 330 DVEFRNVTFRYPGR--DRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEP----DSGQILLDGHDLADY---T 400

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   85 MQAFRwSEMSMVFQSAMnalnpvlpmeeQFCDVI--------MRHTNMTREQARKRAEGLLEIVDIHPSRLtDYP----- 151
Cdd:TIGR02203 401 LASLR-RQVALVSQDVV-----------LFNDTIanniaygrTEQADRAEIERALAAAYAQDFVDKLPLGL-DTPigeng 467

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  152 HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGE 231
Cdd:TIGR02203 468 VLLSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALERLMQ--GRTTLVIAHRLS-TIEKADRIVVMDDGR 544

                         250
                  ....*....|..
gi 694160455  232 LIEVAPSKQILE 243
Cdd:TIGR02203 545 IVERGTHNELLA 556

ABC_YhbG

cd03218

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...

6-245

1.36e-24

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.

Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 99.54 E-value: 1.36e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS-DER 84
Cdd:cd03218    1 LRAENLSKRY----GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKP----DSGKILLDGQDITKLPmHKR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQA---FRWSEMSmVFQSamnalnpvLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTdYPHQFSGGMRQR 161
Cdd:cd03218   73 ARLgigYLPQEAS-IFRK--------LTVEENI-LAVLEIRGLSKKEREEKLEELLEEFHITHLRKS-KASSLSGGERRR 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKeEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQI 241
Cdd:cd03218  142 VEIARALATNPKFLLLDEPFAGVDPIAVQDIQKIIKILK-DRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEI 220


                 ....
gi 694160455 242 LESP 245
Cdd:cd03218  221 AANE 224

SufC

COG0396

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...

7-212

1.53e-24

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 99.76 E-value: 1.53e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   7 SIRNLCVdyitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRlHkpPAF-ITGGEVIFNGENILNYS-DER 84
Cdd:COG0396    2 EIKNLHV----SVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMG-H--PKYeVTSGSILLDGEDILELSpDER 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAfrwsEMSMVFQ---------------SAMNAlnpvlpmeeqfcdviMRHTNMTREQARKRAEGLLEIVDIHPSRLTD 149
Cdd:COG0396   75 ARA----GIFLAFQypveipgvsvsnflrTALNA---------------RRGEELSAREFLKLLKEKMKELGLDEDFLDR 135

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 150 YPHQ-FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITH 212
Cdd:COG0396  136 YVNEgFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNKLRSP-DRGILIITH 198

cbiO

PRK13650

energy-coupling factor transporter ATPase;

26-232

1.67e-24

energy-coupling factor transporter ATPase;

Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 100.58 E-value: 1.67e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGE--NILNYSDERMQafrwseMSMVFQsamna 103
Cdd:PRK13650  24 NDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAES----GQIIIDGDllTEENVWDIRHK------IGMVFQ----- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 104 lNPvlpmEEQFC------DVIMRHTN--MTREQARKRAEGLLEIVDI------HPSRLtdyphqfSGGMRQRLVIAIALA 169
Cdd:PRK13650  89 -NP----DNQFVgatvedDVAFGLENkgIPHEEMKERVNEALELVGMqdfkerEPARL-------SGGQKQRVAIAGAVA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 170 LNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSlMVEFSDRIGIMYSGEL 232
Cdd:PRK13650 157 MRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLD-EVALSDRVLVMKNGQV 218

ABC_MTABC3_MDL1_MDL2

cd03249

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...

21-243

3.76e-24

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.

Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 98.38 E-value: 3.76e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  21 DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSderMQAFRwSEMSMVFQsa 100
Cdd:cd03249   15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDP----TSGEILLDGVDIRDLN---LRWLR-SQIGLVSQ-- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 101 mnalNPVLpmeeqFCDVIMRH--------TNMTREQARKRAEglleivdIHpSRLTDYPHQF-----------SGGMRQR 161
Cdd:cd03249   85 ----EPVL-----FDGTIAENirygkpdaTDEEVEEAAKKAN-------IH-DFIMSLPDGYdtlvgergsqlSGGQKQR 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGELIEVAPSKQI 241
Cdd:cd03249  148 IAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRLS-TIRNADLIAVLQNGQVVEQGTHDEL 224


                 ..
gi 694160455 242 LE 243
Cdd:cd03249  225 MA 226

livG

PRK11300

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

1-245

7.27e-24

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 98.14 E-value: 7.27e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlny 80
Cdd:PRK11300   1 MSQPLLSVSGLMMRF----GGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKP----TGGTILLRGQHI--- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 sdERMQAFRWSEMSMV--FQSA-----MNALNPVLPMEEqfcdvimRHTNM--------------TREQARKRAEGLLEI 139
Cdd:PRK11300  70 --EGLPGHQIARMGVVrtFQHVrlfreMTVIENLLVAQH-------QQLKTglfsgllktpafrrAESEALDRAATWLER 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 140 VDihpsrLTDYPHQFSG----GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLS 215
Cdd:PRK11300 141 VG-----LLEHANRQAGnlayGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMK 215

                        250       260       270
                 ....*....|....*....|....*....|
gi 694160455 216 LMVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:PRK11300 216 LVMGISDRIYVVNQGTPLANGTPEEIRNNP 245

ABCC_Hemolysin

cd03252

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...

27-244

7.59e-24

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.

Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 97.56 E-value: 7.59e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAfrwsEMSMVFQSamNAL-- 104
Cdd:cd03252   20 NISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVP----ENGRVLVDGHDLALADPAWLRR----QVGVVLQE--NVLfn 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 105 ----------NPVLPMEEqfcdvIMRHTNMTREQA--RKRAEGLLEIVDIHPSRLtdyphqfSGGMRQRLVIAIALALNP 172
Cdd:cd03252   90 rsirdnialaDPGMSMER-----VIEAAKLAGAHDfiSELPEGYDTIVGEQGAGL-------SGGQRQRIAIARALIHNP 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 694160455 173 KMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGELIEVAPSKQILES 244
Cdd:cd03252  158 RILIFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLS-TVKNADRIIVMEKGRIVEQGSHDELLAE 226

ModC

COG4148

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...

27-245

1.20e-23

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis

Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 99.40 E-value: 1.20e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKPPA-FIT-GGEVIFNGENILNYSDERMQafrwseMSMVFQSA 100
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKTT----LLRaiagLERPDSgRIRlGGEVLQDSARGIFLPPHRRR------IGYVFQEA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 101 mnALNPVLPMEEqfcdvimrhtN----MTREQARKRAEGLLEIVD---IHPsRLTDYPHQFSGGMRQRLVIAIALALNPK 173
Cdd:COG4148   87 --RLFPHLSVRG----------NllygRKRAPRAERRISFDEVVEllgIGH-LLDRRPATLSGGERQRVAIGRALLSSPR 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 694160455 174 MIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:COG4148  154 LLLMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225

oligo_HPY

pfam08352

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...

233-297

2.92e-23

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.

Pssm-ID: 400588 [Multi-domain] Cd Length: 65 Bit Score: 90.92 E-value: 2.92e-23

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455  233 IEVAPSKQILESPYHPYTKGLGSSFPPLTGPKTKLTGIPGNPLNLLEIPQGCRFQARCDRVHEAC 297
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDPPKRPLYTIPGNVPSLLELPEGCPFAPRCPFATEEC 65

cbiO

PRK13641

energy-coupling factor transporter ATPase;

6-245

4.84e-23

energy-coupling factor transporter ATPase;

Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 96.44 E-value: 4.84e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAG---DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENI-LNYS 81
Cdd:PRK13641   1 MSIKFENVDYIYSPGtpmEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKP----SSGTITIAGYHItPETG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQAFRwSEMSMVFQSAMNAL--NPVLPmeeqfcDVIMRHTNM--TREQARKRAEGLLEIVDIHPSRLTDYPHQFSGG 157
Cdd:PRK13641  77 NKNLKKLR-KKVSLVFQFPEAQLfeNTVLK------DVEFGPKNFgfSEDEAKEKALKWLKKVGLSEDLISKSPFELSGG 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQkIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAP 237
Cdd:PRK13641 150 QMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKEMMQ-LFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHAS 228


                 ....*...
gi 694160455 238 SKQILESP 245
Cdd:PRK13641 229 PKEIFSDK 236

CP_lyasePhnL

TIGR02324

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P ...

24-224

6.41e-23

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.

Pssm-ID: 131377 [Multi-domain] Cd Length: 224 Bit Score: 94.77 E-value: 6.41e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   24 ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGE----NILNYSDERMQAFRWSEMSMVfqs 99
Cdd:TIGR02324  23 VLKNVSLTVNAGECVALSGPSGAGKSTLLKSLYANYLPDS----GRILVRHEgawvDLAQASPREVLEVRRKTIGYV--- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  100 amnalnpvlpmeEQFCDVIMR------------HTNMTREQARKRAEGLLEIVDIhPSRLTD-YPHQFSGGMRQRLVIAI 166
Cdd:TIGR02324  96 ------------SQFLRVIPRvsalevvaepllERGVPREAARARARELLARLNI-PERLWHlPPATFSGGEQQRVNIAR 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455  167 ALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRI 224
Cdd:TIGR02324 163 GFIADYPILLLDEPTASLDAANRQVVVELIAEAKAR-GAALIGIFHDEEVRELVADRV 219

ABCC_MRP_domain2

cd03244

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...

6-234

9.83e-23

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 94.10 E-value: 9.83e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVraCNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLhkppAFITGGEVIFNGENIlnySDERM 85
Cdd:cd03244    3 IEFKNVSLRYRPNLPPV--LKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRL----VELSSGSILIDGVDI---SKIGL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQsamnalNPVL----------PMEEqfcdvimrHTNMTREQARKRAeGLLEIVDIHP----SRLTDYP 151
Cdd:cd03244   74 HDLR-SRISIIPQ------DPVLfsgtirsnldPFGE--------YSDEELWQALERV-GLKEFVESLPggldTVVEEGG 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQkiyALKEEF-GFSILFITHDLSLMVEfSDRIGIMYSG 230
Cdd:cd03244  138 ENLSVGQRQLLCLARALLRKSKILVLDEATASVDPETDALIQK---TIREAFkDCTVLTIAHRLDTIID-SDRILVLDKG 213


                 ....
gi 694160455 231 ELIE 234
Cdd:cd03244  214 RVVE 217

cbiO

PRK13646

energy-coupling factor transporter ATPase;

13-244

1.59e-22

energy-coupling factor transporter ATPase;

Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 95.23 E-value: 1.59e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  13 VDYITAAG---DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS-DERMQAF 88
Cdd:PRK13646   8 VSYTYQKGtpyEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKP----TTGTVTVDDITITHKTkDKYIRPV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  89 RwSEMSMVFQsamnalnpvLPMEEQFCDVIMRHT-------NMTREQARKRAEGLLeiVDIHPSR--LTDYPHQFSGGMR 159
Cdd:PRK13646  84 R-KRIGMVFQ---------FPESQLFEDTVEREIifgpknfKMNLDEVKNYAHRLL--MDLGFSRdvMSQSPFQMSGGQM 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 160 QRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSK 239
Cdd:PRK13646 152 RKIAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPK 231


                 ....*
gi 694160455 240 QILES 244
Cdd:PRK13646 232 ELFKD 236

LptB

COG1137

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...

4-257

1.86e-22

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 93.94 E-value: 1.86e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS-D 82
Cdd:COG1137    2 MTLEAENLVKSY----GKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKP----DSGRIFLDGEDITHLPmH 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 ERMQA-----------FRwsEMSmVFQSAMnalnpvlpmeeqfcdVIMRHTNMTREQARKRAEGLLEivDIHPSRLTDYP 151
Cdd:COG1137   74 KRARLgigylpqeasiFR--KLT-VEDNIL---------------AVLELRKLSKKEREERLEELLE--EFGITHLRKSK 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 -HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILfIT-HD----LSLMvefsDRIG 225
Cdd:COG1137  134 aYSLSGGERRRVEIARALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKER-GIGVL-ITdHNvretLGIC----DRAY 207

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 694160455 226 IMYSGELIEVAPSKQILESP-----YhpytkgLGSSF 257
Cdd:COG1137  208 IISEGKVLAEGTPEEILNNPlvrkvY------LGEDF 238

artP

PRK11124

arginine transporter ATP-binding subunit; Provisional

6-234

3.06e-22

arginine transporter ATP-binding subunit; Provisional

Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 93.54 E-value: 3.06e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLhkppafitggEVIFNGE-NILNY---- 80
Cdd:PRK11124   3 IQLNGINCFY----GAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLL----------EMPRSGTlNIAGNhfdf 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 ----SDERMQAFRwSEMSMVFQSAmnALNPVLPMEEQFCDVIMRHTNMTREQARKRAEGLLEIVdihpsRLTD----YPH 152
Cdd:PRK11124  69 sktpSDKAIRELR-RNVGMVFQQY--NLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERL-----RLKPyadrFPL 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK11124 141 HLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAET-GITQVIVTHEVEVARKTASRVVYMENGHI 219


                 ..
gi 694160455 233 IE 234
Cdd:PRK11124 220 VE 221

TagH

COG1134

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...

1-243

5.43e-22

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 92.84 E-value: 5.43e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTaPLISIRNLCVDY------------------ITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkpp 62
Cdd:COG1134    1 MS-SMIEVENVSKSYrlyhepsrslkelllrrrRTRREEFWALKDVSFEVERGESVGIIGRNGAGKST----LLKL---- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  63 afITG------GEVIFNGenilnysdeRMQAFrwSEMSMVFQSAM--------NALnpvlpmeeqfcdvIMrhtNMTREQ 128
Cdd:COG1134   72 --IAGileptsGRVEVNG---------RVSAL--LELGAGFHPELtgreniylNGR-------------LL---GLSRKE 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 129 ARKRAEgllEIVDIhpSRLTDYPHQ----FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfG 204
Cdd:COG1134  123 IDEKFD---EIVEF--AELGDFIDQpvktYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES-G 196

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 694160455 205 FSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILE 243
Cdd:COG1134  197 RTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIA 235

ABCC_TAP

cd03248

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...

21-232

8.80e-22

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.

Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 91.76 E-value: 8.80e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  21 DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQafrwSEMSMVFQSa 100
Cdd:cd03248   26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQP----QGGQVLLDGKPISQYEHKYLH----SKVSLVGQE- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 101 mnalnPVLpMEEQFCDVIM-----RHTNMTREQARKRAEG--LLEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALNPK 173
Cdd:cd03248   97 -----PVL-FARSLQDNIAyglqsCSFECVKEAAQKAHAHsfISELASGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQ 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 174 MIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLmVEFSDRIGIMYSGEL 232
Cdd:cd03248  171 VLILDEATSALDAESEQQVQQALYDWPER--RTVLVIAHRLST-VERADQILVLDGGRI 226

PRK14243

phosphate transporter ATP-binding protein; Provisional

2-251

9.56e-22

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 92.54 E-value: 9.56e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   2 TAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHK-PPAFITGGEVIFNGENiLNY 80
Cdd:PRK14243   7 TETVLRTENLNVYY----GSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDlIPGFRVEGKVTFHGKN-LYA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFRwSEMSMVFQSAMnalnpvlPMEEQFCDVIM-------RHTNMTR--EQARKRAEGLLEIVDihpsRLTDYP 151
Cdd:PRK14243  82 PDVDPVEVR-RRIGMVFQKPN-------PFPKSIYDNIAygaringYKGDMDElvERSLRQAALWDEVKD----KLKQSG 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEFSDRI------- 224
Cdd:PRK14243 150 LSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQ--YTIIIVTHNMQQAARVSDMTaffnvel 227

                        250       260       270
                 ....*....|....*....|....*....|
gi 694160455 225 ---GIMYsGELIEVAPSKQILESPYHPYTK 251
Cdd:PRK14243 228 tegGGRY-GYLVEFDRTEKIFNSPQQQATR 256

ABC_FeS_Assembly

cd03217

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...

6-243

1.73e-21

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.

Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 90.28 E-value: 1.73e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVdyitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMrlHKPPAFITGGEVIFNGENILNYS-DER 84
Cdd:cd03217    1 LEIKDLHV----SVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIM--GHPKYEVTEGEILFKGEDITDLPpEER 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAfrwsEMSMVFQSamnalnpvlPME------EQFcdviMRHTNmtreqarkraEGlleivdihpsrltdyphqFSGGM 158
Cdd:cd03217   75 ARL----GIFLAFQY---------PPEipgvknADF----LRYVN----------EG------------------FSGGE 109

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITH--DLSLMVEfSDRIGIMYSGELIEVA 236
Cdd:cd03217  110 KKRNEILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREE-GKSVLIITHyqRLLDYIK-PDRVHVLYDGRIVKSG 187


                 ....*..
gi 694160455 237 PSKQILE 243
Cdd:cd03217  188 DKELALE 194

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

3-241

2.18e-21

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 94.35 E-value: 2.18e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLcvdyiTAAGDVracnNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS- 81
Cdd:PRK15439 266 APVLTVEDL-----TGEGFR----NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPA----RGGRIMLNGKEINALSt 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQAfrwsemSMVFqsamnalnpvLPMEEQ----FCDVIMR-------HTNMTREQARKRAEGLLE----IVDIHPSR 146
Cdd:PRK15439 333 AQRLAR------GLVY----------LPEDRQssglYLDAPLAwnvcaltHNRRGFWIKPARENAVLEryrrALNIKFNH 396

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 147 LTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGI 226
Cdd:PRK15439 397 AEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLV 475

                        250
                 ....*....|....*
gi 694160455 227 MYSGELIEVAPSKQI 241
Cdd:PRK15439 476 MHQGEISGALTGAAI 490

3a01208

TIGR00958

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

21-245

2.23e-21

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 94.79 E-value: 2.23e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   21 DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAfrwsemsmvfQSA 100
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQP----TGGQVLLDGVPLVQYDHHYLHR----------QVA 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  101 MNALNPVLpMEEQFCDVI---MRHTNMTREQARKRAEG----LLEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALNPK 173
Cdd:TIGR00958 559 LVGQEPVL-FSGSVRENIaygLTDTPDEEIMAAAKAANahdfIMEFPNGYDTEVGEKGSQLSGGQKQRIAIARALVRKPR 637

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 694160455  174 MIIMDEPTTALDVVVQreilQKIYALKEEFGFSILFITHDLSLmVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:TIGR00958 638 VLILDEATSALDAECE----QLLQESRSRASRTVLLIAHRLST-VERADQILVLKKGSVVEMGTHKQLMEDQ 704

PRK14258

phosphate ABC transporter ATP-binding protein; Provisional

4-251

2.28e-21

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 91.64 E-value: 2.28e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYITAagdvRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFI-TGGEVIFNGENILnysD 82
Cdd:PRK14258   6 PAIKVNNLSFYYDTQ----KILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVrVEGRVEFFNQNIY---E 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 ERMQAFRWS-EMSMVFQSAmnalnPVLPME-----EQFCDVIMRHTNM----TREQARKRAEGLLEIVD-IHPSRLtdyp 151
Cdd:PRK14258  79 RRVNLNRLRrQVSMVHPKP-----NLFPMSvydnvAYGVKIVGWRPKLeiddIVESALKDADLWDEIKHkIHKSAL---- 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 hQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYS-- 229
Cdd:PRK14258 150 -DLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGne 228

                        250       260
                 ....*....|....*....|....*
gi 694160455 230 ---GELIEVAPSKQILESPYHPYTK 251
Cdd:PRK14258 229 nriGQLVEFGLTKKIFNSPHDSRTR 253

PRK10584

putative ABC transporter ATP-binding protein YbbA; Provisional

28-236

3.80e-21

putative ABC transporter ATP-binding protein YbbA; Provisional

Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 90.22 E-value: 3.80e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  28 VSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFRWSEMSMVFQSAM-----N 102
Cdd:PRK10584  29 VELVVKRGETIALIGESGSGKSTLLAILAGLDDG----SSGEVSLVGQPLHQMDEEARAKLRAKHVGFVFQSFMliptlN 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 103 ALNPV-LPmeeqfcdVIMRhtNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPT 181
Cdd:PRK10584 105 ALENVeLP-------ALLR--GESSRQSRNGAKALLEQLGLG-KRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPT 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 182 TALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMySGELIEVA 236
Cdd:PRK10584 175 GNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRLRLV-NGQLQEEA 228

ABCC_cytochrome_bd

cd03247

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...

6-234

6.39e-21

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.

Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 88.14 E-value: 6.39e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERM 85
Cdd:cd03247    1 LSINNVSFSY--PEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKP----QQGEITLDGVPVSDLEKALS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAfrwseMSMVFQSamnalnPVLpmeeqFCDVIMrhTNMTReqarkraeglleivdihpsrltdyphQFSGGMRQRLVIA 165
Cdd:cd03247   75 SL-----ISVLNQR------PYL-----FDTTLR--NNLGR--------------------------RFSGGERQRLALA 110

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 166 IALALNPKMIIMDEPTTALDVVVQREILQKIY-ALKEEfgfSILFITHDLSLMvEFSDRIGIMYSGELIE 234
Cdd:cd03247  111 RILLQDAPIVLLDEPTVGLDPITERQLLSLIFeVLKDK---TLIWITHHLTGI-EHMDKILFLENGKIIM 176

ModF

COG1119

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...

4-214

6.83e-21

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];

Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 89.76 E-value: 6.83e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRL---HKPPAFitGGEV-IFN----GE 75
Cdd:COG1119    2 PLLELRNVTVRR----GGKTILDDISWTVKPGEHWAILGPNGAGKST----LLSLitgDLPPTY--GNDVrLFGerrgGE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  76 NIlnysdermqafrW----------SEMSMVFQSAMNALNPVLpmeEQFCDVIMRHTNMTREQaRKRAEGLLEIVDIhpS 145
Cdd:COG1119   72 DV------------WelrkriglvsPALQLRFPRDETVLDVVL---SGFFDSIGLYREPTDEQ-RERARELLELLGL--A 133

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 146 RLTDYP-HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDL 214
Cdd:COG1119  134 HLADRPfGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHV 203

cbiO

PRK13634

cobalt transporter ATP-binding subunit; Provisional

23-254

8.13e-21

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 90.46 E-value: 8.13e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  23 RACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDER-MQAFRwSEMSMVFQSAM 101
Cdd:PRK13634  21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQP----TSGTVTIGERVITAGKKNKkLKPLR-KKVGIVFQFPE 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 102 NALnpvlpMEEQFC-DVIMRHTN--MTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMD 178
Cdd:PRK13634  96 HQL-----FEETVEkDICFGPMNfgVSEEDAKQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLD 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 179 EPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHPYTKGLG 254
Cdd:PRK13634 171 EPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPDELEAIGLD 246

PRK13651

cobalt transporter ATP-binding subunit; Provisional

23-243

8.87e-21

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 90.53 E-value: 8.87e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  23 RACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNysDERMQAFRWSEMSMVFQSA-- 100
Cdd:PRK13651  21 KALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLP----DTGTIEWIFKDEKN--KKKTKEKEKVLEKLVIQKTrf 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 101 -----MNALNPVLPMEEQFC-----------DVIM--RHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMRQRL 162
Cdd:PRK13651  95 kkikkIKEIRRRVGVVFQFAeyqlfeqtiekDIIFgpVSMGVSKEEAKKRAAKYIELVGLDESYLQRSPFELSGGQKRRV 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 163 VIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:PRK13651 175 ALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDIL 253


                 .
gi 694160455 243 E 243
Cdd:PRK13651 254 S 254

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

1-230

1.38e-20

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 92.15 E-value: 1.38e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENiLNY 80
Cdd:PRK09700   1 MATPYISMAGIGKSF----GPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEP----TKGTITINNIN-YNK 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAfrWSEMSMVFQSaMNALNPVLPMEEQFcdvIMRHtnMTRE----------QARKRAEGLLEIVDIHPSrLTDY 150
Cdd:PRK09700  72 LDHKLAA--QLGIGIIYQE-LSVIDELTVLENLY---IGRH--LTKKvcgvniidwrEMRVRAAMMLLRVGLKVD-LDEK 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 151 PHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALdvvVQREIlQKIYA----LKEEfGFSILFITHDLSLMVEFSDRIGI 226
Cdd:PRK09700 143 VANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSL---TNKEV-DYLFLimnqLRKE-GTAIVYISHKLAEIRRICDRYTV 217


                 ....
gi 694160455 227 MYSG 230
Cdd:PRK09700 218 MKDG 221

ABCC_Glucan_exporter_like

cd03254

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...

27-244

1.54e-20

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 88.44 E-value: 1.54e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQafrwSEMSMVFQSamnalnP 106
Cdd:cd03254   21 DINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDP----QKGQILIDGIDIRDISRKSLR----SMIGVVLQD------T 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 107 VLpmeeqFCDVIMRHTNMTREQAR-KRAEGLLEIVDIHP--SRLTD-YPHQ-------FSGGMRQRLVIAIALALNPKMI 175
Cdd:cd03254   87 FL-----FSGTIMENIRLGRPNATdEEVIEAAKEAGAHDfiMKLPNgYDTVlgenggnLSQGERQLLAIARAMLRDPKIL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 176 IMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGELIEVAPSKQILES 244
Cdd:cd03254  162 ILDEATSNIDTETEKLIQEALEKLMK--GRTSIIIAHRLS-TIKNADKILVLDDGKIIEEGTHDELLAK 227

PRK13537

nodulation factor ABC transporter ATP-binding protein NodI;

1-241

2.28e-20

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 89.48 E-value: 2.28e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENIlny 80
Cdd:PRK13537   3 MSVAPIDFRNVEKRY----GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDA----GSISLCGEPV--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 sDERMQAFRwSEMSMVFQsaMNALNPVLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQ 160
Cdd:PRK13537  72 -PSRARHAR-QRVGVVPQ--FDNLDPDFTVRENLL-VFGRYFGLSAAAARALVPPLLEFAKLE-NKADAKVGELSGGMKR 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 161 RLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI-EVAPSK 239
Cdd:PRK13537 146 RLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIaEGAPHA 224


                 ..
gi 694160455 240 QI 241
Cdd:PRK13537 225 LI 226

ssuB

PRK11247

aliphatic sulfonates transport ATP-binding subunit; Provisional

20-232

2.52e-20

aliphatic sulfonates transport ATP-binding subunit; Provisional

Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 88.58 E-value: 2.52e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIfNGENILNYSDErmqafrwsEMSMVFQS 99
Cdd:PRK11247  23 GERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETP----SAGELL-AGTAPLAEARE--------DTRLMFQD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 AMnalnpVLPMEEQFCDVIMRHTNMTREQARK--RAEGLLEivdihpsRLTDYPHQFSGGMRQRLVIAIALALNPKMIIM 177
Cdd:PRK11247  90 AR-----LLPWKKVIDNVGLGLKGQWRDAALQalAAVGLAD-------RANEWPAALSGGQKQRVALARALIHRPGLLLL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 178 DEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK11247 158 DEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212

ABC_NatA_like

cd03267

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...

21-233

4.81e-20

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.

Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 87.39 E-value: 4.81e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  21 DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGenILNYsdERMQAFRwSEMSMVFQSA 100
Cdd:cd03267   33 EVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQP----TSGEVRVAG--LVPW--KRRKKFL-RRIGVVFGQK 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 101 mNALNPVLPMEEQFcdVIMRHT-NMTREQARKRAEGLLEIVDIhpSRLTDYP-HQFSGGMRQRLVIAIALALNPKMIIMD 178
Cdd:cd03267  104 -TQLWWDLPVIDSF--YLLAAIyDLPPARFKKRLDELSELLDL--EELLDTPvRQLSLGQRMRAEIAAALLHEPEILFLD 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 179 EPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03267  179 EPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233

cbiO

PRK13631

cobalt transporter ATP-binding subunit; Provisional

5-250

5.32e-20

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 88.75 E-value: 5.32e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNL-CVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPP-AFITGGEVI----FNGENIL 78
Cdd:PRK13631  21 ILRVKNLyCVFDEKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKyGTIQVGDIYigdkKNNHELI 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDER-MQAFR--WSEMSMVFQsamnalnpvLPMEEQFCDVIMRHT-------NMTREQARKRAEGLLEIVDIHPSRLT 148
Cdd:PRK13631 101 TNPYSKkIKNFKelRRRVSMVFQ---------FPEYQLFKDTIEKDImfgpvalGVKKSEAKKLAKFYLNKMGLDDSYLE 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 149 DYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMY 228
Cdd:PRK13631 172 RSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVIVMD 250

                        250       260
                 ....*....|....*....|..
gi 694160455 229 SGELIEVApskqileSPYHPYT 250
Cdd:PRK13631 251 KGKILKTG-------TPYEIFT 265

YnjD

COG4136

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...

27-213

5.71e-20

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];

Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 86.38 E-value: 5.71e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKSTVaFSLMRLHKPPAFITGGEVIFNGENILNYSDERMQafrwseMSMVFQSAMnaLNP 106
Cdd:COG4136   19 PLSLTVAPGEILTLMGPSGSGKSTL-LAAIAGTLSPAFSASGEVLLNGRRLTALPAEQRR------IGILFQDDL--LFP 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 107 VLPMEEQFCDVIMRhtNMTREQARKRAEGLLEIVDihpsrLTDY----PHQFSGGMRQRLVIAIALALNPKMIIMDEPTT 182
Cdd:COG4136   90 HLSVGENLAFALPP--TIGRAQRRARVEQALEEAG-----LAGFadrdPATLSGGQRARVALLRALLAEPRALLLDEPFS 162

                        170       180       190
                 ....*....|....*....|....*....|.
gi 694160455 183 ALDVVVQREILQKIYALKEEFGFSILFITHD 213
Cdd:COG4136  163 KLDAALRAQFREFVFEQIRQRGIPALLVTHD 193

PRK10575

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

24-245

6.52e-20

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 87.54 E-value: 6.52e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  24 ACNNVSFDIA-------------PGEVFGLAGESGCGKSTVAFSLMRlHKPPafiTGGEVIFNGENILNYSdermqafrw 90
Cdd:PRK10575  13 ALRNVSFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKMLGR-HQPP---SEGEILLDAQPLESWS--------- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  91 semSMVFQSAMNALNPVLPMEEQFCD----VIMR---HTNMTREQA--RKRAEGLLEIVDIHP--SRLTDyphQFSGGMR 159
Cdd:PRK10575  80 ---SKAFARKVAYLPQQLPAAEGMTVrelvAIGRypwHGALGRFGAadREKVEEAISLVGLKPlaHRLVD---SLSGGER 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 160 QRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSK 239
Cdd:PRK10575 154 QRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPA 233


                 ....*.
gi 694160455 240 QILESP 245
Cdd:PRK10575 234 ELMRGE 239

ABCC_bacteriocin_exporters

cd03245

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...

27-233

7.72e-20

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.

Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 86.10 E-value: 7.72e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENI--LNYSDERmqafrwSEMSMVFQsamnal 104
Cdd:cd03245   22 NVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKP----TSGSVLLDGTDIrqLDPADLR------RNIGYVPQ------ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 105 NPVLpmeeqFCDVI-----MRHTNMTREQARKRAE--GLLEIVDIHPSRLtDYP-----HQFSGGMRQRLVIAIALALNP 172
Cdd:cd03245   86 DVTL-----FYGTLrdnitLGAPLADDERILRAAElaGVTDFVNKHPNGL-DLQigergRGLSGGQRQAVALARALLNDP 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 173 KMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGELI 233
Cdd:cd03245  160 PILLLDEPTSAMDMNSEERLKERLRQLLG--DKTLIIITHRPS-LLDLVDRIIVMDSGRIV 217

tauB

PRK11248

taurine ABC transporter ATP-binding subunit;

5-214

1.02e-19

taurine ABC transporter ATP-binding subunit;

Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 86.68 E-value: 1.02e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLHKPPAFITGGEVIFNGENILNYSDER 84
Cdd:PRK11248   1 MLQISHLYADY----GGKPALEDINLTLESGELLVVLGPSGCGKTT----LLNLIAGFVPYQHGSITLDGKPVEGPGAER 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 mqafrwsemSMVFQSamNALnpvLPMEEQFCDVI--MRHTNMTREQARKRAEGLLEIVDIHPSRlTDYPHQFSGGMRQRL 162
Cdd:PRK11248  73 ---------GVVFQN--EGL---LPWRNVQDNVAfgLQLAGVEKMQRLEIAHQMLKKVGLEGAE-KRYIWQLSGGQRQRV 137

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 694160455 163 VIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDL 214
Cdd:PRK11248 138 GIARALAANPQLLLLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDI 189

PRK11000

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

6-235

1.34e-19

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 88.16 E-value: 1.34e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITGGEVIFNGEniLNYSDERM 85
Cdd:PRK11000   4 VTLRNVTKAY----GDVVISKDINLDIHEGEFVVFVGPSGCGKST----LLRM------IAGLEDITSGD--LFIGEKRM 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRWSEMS--MVFQSAmnALNPVLPMEEqfcdvimrhtNMT---------REQARKRAEGLLEIVDIhpSRLTD-YPHQ 153
Cdd:PRK11000  68 NDVPPAERGvgMVFQSY--ALYPHLSVAE----------NMSfglklagakKEEINQRVNQVAEVLQL--AHLLDrKPKA 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVV--VQREIlqKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGE 231
Cdd:PRK11000 134 LSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAAlrVQMRI--EISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGR 211


                 ....
gi 694160455 232 LIEV 235
Cdd:PRK11000 212 VAQV 215

cbiO

PRK13649

energy-coupling factor transporter ATPase;

6-243

1.45e-19

energy-coupling factor transporter ATPase;

Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 86.72 E-value: 1.45e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNlcVDYITAAG---DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSD 82
Cdd:PRK13649   3 INLQN--VSYTYQAGtpfEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVP----TQGSVRVDDTLITSTSK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 ERMQAFRWSEMSMVFQSAMNALnpvlpMEEQFC-DVIMRHTN--MTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMR 159
Cdd:PRK13649  77 NKDIKQIRKKVGLVFQFPESQL-----FEETVLkDVAFGPQNfgVSQEEAEALAREKLALVGISESLFEKNPFELSGGQM 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 160 QRLVIAIALALNPKMIIMDEPTTALDVVVQREiLQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSK 239
Cdd:PRK13649 152 RRVAIAGILAMEPKILVLDEPTAGLDPKGRKE-LMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPK 230


                 ....
gi 694160455 240 QILE 243
Cdd:PRK13649 231 DIFQ 234

cbiO

PRK13638

energy-coupling factor ABC transporter ATP-binding protein;

21-233

1.46e-19

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 86.60 E-value: 1.46e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  21 DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENiLNYSDERMQAFRwSEMSMVFQSa 100
Cdd:PRK13638  13 DEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQK----GAVLWQGKP-LDYSKRGLLALR-QQVATVFQD- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 101 mnalnpvlPMEEQFCDVI-------MRHTNMTREQARKRAEGLLEIVDIHpsRLTDYPHQ-FSGGMRQRLVIAIALALNP 172
Cdd:PRK13638  86 --------PEQQIFYTDIdsdiafsLRNLGVPEAEITRRVDEALTLVDAQ--HFRHQPIQcLSHGQKKRVAIAGALVLQA 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 173 KMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:PRK13638 156 RYLLLDEPTAGLDPAGRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQIL 215

ThiQ

COG3840

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

29-248

1.68e-19

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 85.58 E-value: 1.68e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  29 SFDIAPGEVFGLAGESGCGKSTVaFSLMRLHKPPAfitGGEVIFNGENILNYS-DERmqafrwsEMSMVFQSamNALNPV 107
Cdd:COG3840   19 DLTIAAGERVAILGPSGAGKSTL-LNLIAGFLPPD---SGRILWNGQDLTALPpAER-------PVSMLFQE--NNLFPH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 108 LPMEEQFCdvIMRHTNM--TREQaRKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALD 185
Cdd:COG3840   86 LTVAQNIG--LGLRPGLklTAEQ-RAQVEQALERVGLA-GLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 186 VVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESPYHP 248
Cdd:COG3840  162 PALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPP 224

CydD

TIGR02857

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...

3-224

1.91e-19

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD

Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 88.88 E-value: 1.91e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    3 APLISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSd 82
Cdd:TIGR02857 319 ASSLEFSGVSVAY---PGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDP----TEGSIAVNGVPLADAD- 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   83 ermQAFRWSEMSMVFQsamnalNPVLpmeeqFCDVIMRHTNMTR--------EQARKRAeGLLEIVDIHP----SRLTDY 150
Cdd:TIGR02857 391 ---ADSWRDQIAWVPQ------HPFL-----FAGTIAENIRLARpdasdaeiREALERA-GLDEFVAALPqgldTPIGEG 455

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455  151 PHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSLMvEFSDRI 224
Cdd:TIGR02857 456 GAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALA-ALADRI 526

ABCG_White

cd03234

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...

21-233

1.96e-19

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.

Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 85.40 E-value: 1.96e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  21 DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLM-RLHKPPafITGGEVIFNGENIlnySDERMQafrwSEMSMVFQS 99
Cdd:cd03234   19 YARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISgRVEGGG--TTSGQILFNGQPR---KPDQFQ----KCVAYVRQD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 amNALNPVLPMEEQ--FCDVIMRHTNMTREQARKRAEGLLeIVDIHPSRLTD-YPHQFSGGMRQRLVIAIALALNPKMII 176
Cdd:cd03234   90 --DILLPGLTVRETltYTAILRLPRKSSDAIRKKRVEDVL-LRDLALTRIGGnLVKGISGGERRRVSIAVQLLWDPKVLI 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 177 MDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:cd03234  167 LDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIV 223

ABCC_Protease_Secretion

cd03246

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...

6-232

2.25e-19

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.

Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 83.80 E-value: 2.25e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnysderm 85
Cdd:cd03246    1 LEVENVSFRY--PGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRP----TSGRVRLDGADI-------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 qafrwsemsmvFQSAMNALNP---VLPMEEQ-FCDVImrhtnmtreqarkrAEGLLeivdihpsrltdyphqfSGGMRQR 161
Cdd:cd03246   67 -----------SQWDPNELGDhvgYLPQDDElFSGSI--------------AENIL-----------------SGGQRQR 104

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLmVEFSDRIGIMYSGEL 232
Cdd:cd03246  105 LGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAA-GATRIVIAHRPET-LASADRILVLEDGRV 173

ABCC_NFT1

cd03369

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...

6-236

2.98e-19

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 84.39 E-value: 2.98e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDERM 85
Cdd:cd03369    7 IEVENLSVRY--APDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEA----EEGKIEIDGIDI---STIPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQsamnalNPVLpmeeqFCDVIMRHTNMTREQARKRAEGLLEIvdihpsrlTDYPHQFSGGMRQRLVIA 165
Cdd:cd03369   78 EDLR-SSLTIIPQ------DPTL-----FSGTIRSNLDPFDEYSDEEIYGALRV--------SEGGLNLSQGQRQLLCLA 137

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 694160455 166 IALALNPKMIIMDEPTTALDVVVQREIlQKIyaLKEEF-GFSILFITHDLSLMVEFsDRIGIMYSGELIEVA 236
Cdd:cd03369  138 RALLKRPRVLVLDEATASIDYATDALI-QKT--IREEFtNSTILTIAHRLRTIIDY-DKILVMDAGEVKEYD 205

PRK11831

phospholipid ABC transporter ATP-binding protein MlaF;

2-245

3.12e-19

phospholipid ABC transporter ATP-binding protein MlaF;

Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 85.59 E-value: 3.12e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   2 TAPLISIRNLCVdyitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRL---HKPPafiTGGEVIFNGENIL 78
Cdd:PRK11831   4 VANLVDMRGVSF----TRGNRCIFDNISLTVPRGKITAIMGPSGIGKTT----LLRLiggQIAP---DHGEILFDGENIP 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDERMQAFRwSEMSMVFQSA-----MNAL-NPVLPMEE--QFCDVIMRHTNMTREQArkraEGLLEIVDIHPSRLtdy 150
Cdd:PRK11831  73 AMSRSRLYTVR-KRMSMLFQSGalftdMNVFdNVAYPLREhtQLPAPLLHSTVMMKLEA----VGLRGAAKLMPSEL--- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 151 phqfSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSG 230
Cdd:PRK11831 145 ----SGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADK 220

                        250
                 ....*....|....*
gi 694160455 231 ELIEVAPSKQILESP 245
Cdd:PRK11831 221 KIVAHGSAQALQANP 235

hmuV

PRK13548

hemin importer ATP-binding subunit; Provisional

4-242

3.50e-19

hemin importer ATP-binding subunit; Provisional

Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 85.21 E-value: 3.50e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVdyitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITG------GEVIFNGENI 77
Cdd:PRK13548   1 AMLEARNLSV----RLGGRTLLDDVSLTLRPGEVVAILGPNGAGKST----LLRA------LSGelspdsGEVRLNGRPL 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  78 LNYSDERMQAFRwsemSMVFQSAmnALNPVLPMEEqfcdVI-M-RHTNMTREQARKRA-EGLLEIVDIHPSRLTDYPhQF 154
Cdd:PRK13548  67 ADWSPAELARRR----AVLPQHS--SLSFPFTVEE----VVaMgRAPHGLSRAEDDALvAAALAQVDLAHLAGRDYP-QL 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAIALA------LNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMY 228
Cdd:PRK13548 136 SGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLH 215

                        250
                 ....*....|....
gi 694160455 229 SGELIEVAPSKQIL 242
Cdd:PRK13548 216 QGRLVADGTPAEVL 229

PRK10535

macrolide ABC transporter ATP-binding protein/permease MacB;

1-262

4.47e-19

macrolide ABC transporter ATP-binding protein/permease MacB;

Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 87.86 E-value: 4.47e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTApLISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNY 80
Cdd:PRK10535   1 MTA-LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKP----TSGTYRVAGQDVATL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFRWSEMSMVFQ-----SAMNAlnpvlpmeEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFS 155
Cdd:PRK10535  76 DADALAQLRREHFGFIFQryhllSHLTA--------AQNVEVPAVYAGLERKQRLLRAQELLQRLGLE-DRVEYQPSQLS 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 156 GGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEfSDRIGIMYSGELIEV 235
Cdd:PRK10535 147 GGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDR-GHTVIIVTHDPQVAAQ-AERVIEIRDGEIVRN 224

                        250       260
                 ....*....|....*....|....*..
gi 694160455 236 APSKqilesPYHPYTKGLGSSFPPLTG 262
Cdd:PRK10535 225 PPAQ-----EKVNVAGGTEPVVNTASG 246

COG4586

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

6-233

4.87e-19

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 85.91 E-value: 4.87e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITA---AG--------------DVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR-----LHkpPa 63
Cdd:COG4586    2 IEVENLSKTYRVYekePGlkgalkglfrreyrEVEAVDDISFTIEPGEIVGFIGPNGAGKST----TIKmltgiLV--P- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  64 fiTGGEVIFNGENILnysdERMQAFRwSEMSMVF----QsamnaLNPVLPMEEQFcdVIMRHT-NMTREQARKRAEGLLE 138
Cdd:COG4586   75 --TSGEVRVLGYVPF----KRRKEFA-RRIGVVFgqrsQ-----LWWDLPAIDSF--RLLKAIyRIPDAEYKKRLDELVE 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 139 IVDIHPsrLTDYP-HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLM 217
Cdd:COG4586  141 LLDLGE--LLDTPvRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDI 218

                        250
                 ....*....|....*.
gi 694160455 218 VEFSDRIGIMYSGELI 233
Cdd:COG4586  219 EALCDRVIVIDHGRII 234

ABC_KpsT_Wzt

cd03220

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...

6-234

6.93e-19

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.

Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 83.74 E-value: 6.93e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDY------------------ITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITG 67
Cdd:cd03220    1 IELENVSKSYptykggssslkklgilgrKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKST----LLRL------LAG 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  68 ------GEVIFNGEnilnysdermqafrwseMSMVFqsAMNA-LNPVLPMEEqfcDVIMRHT--NMTREQARKRAEgllE 138
Cdd:cd03220   71 iyppdsGTVTVRGR-----------------VSSLL--GLGGgFNPELTGRE---NIYLNGRllGLSRKEIDEKID---E 125

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 139 IVDIhpSRLTDYPHQ----FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDL 214
Cdd:cd03220  126 IIEF--SELGDFIDLpvktYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQ-GKTVILVSHDP 202

                        250       260
                 ....*....|....*....|
gi 694160455 215 SLMVEFSDRIGIMYSGELIE 234
Cdd:cd03220  203 SSIKRLCDRALVLEKGKIRF 222

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

6-233

9.59e-19

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 83.91 E-value: 9.59e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERM 85
Cdd:PRK11231   3 LRTENLTVGY----GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTP----QSGTVFLGDKPISMLSSRQL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 --------QAFRWSEMSMVFQSAMNALNPVLPM-------EEQFCDVIMRHTnmtreqarkraegllEIVDIHPSRLTDy 150
Cdd:PRK11231  75 arrlallpQHHLTPEGITVRELVAYGRSPWLSLwgrlsaeDNARVNQAMEQT---------------RINHLADRRLTD- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 151 phqFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSG 230
Cdd:PRK11231 139 ---LSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANG 214


                 ...
gi 694160455 231 ELI 233
Cdd:PRK11231 215 HVM 217

NHLM_micro_ABC1

TIGR03796

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...

26-234

1.15e-18

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]

Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 86.54 E-value: 1.15e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQafrwSEMSMVFQSA----- 100
Cdd:TIGR03796 496 ENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQP----WSGEILFDGIPREEIPREVLA----NSVAMVDQDIflfeg 567

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  101 -----MNALNPVLPMEEQfcdvimrhtnmtrEQARKRAEglleIVDIHPSRLTDYPHQ-------FSGGMRQRLVIAIAL 168
Cdd:TIGR03796 568 tvrdnLTLWDPTIPDADL-------------VRACKDAA----IHDVITSRPGGYDAElaegganLSGGQRQRLEIARAL 630

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455  169 ALNPKMIIMDEPTTALDVVVQREILQKIyalkEEFGFSILFITHDLSLMVEfSDRIGIMYSGELIE 234
Cdd:TIGR03796 631 VRNPSILILDEATSALDPETEKIIDDNL----RRRGCTCIIVAHRLSTIRD-CDEIIVLERGKVVQ 691

PRK11160

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

2-234

1.99e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 85.65 E-value: 1.99e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   2 TAPLISIRNLCVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYS 81
Cdd:PRK11160 335 DQVSLTLNNVSFTY--PDQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDP----QQGEILLNGQPIADYS 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DermQAFRwSEMSMVFQ-----SAMNALNPVL----PMEEQFCDVIMRhTNMtreqarkraEGLLEIVDIHPSRLTDYPH 152
Cdd:PRK11160 409 E---AALR-QAISVVSQrvhlfSATLRDNLLLaapnASDEALIEVLQQ-VGL---------EKLLEDDKGLNAWLGEGGR 474

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSLMVEFsDRIGIMYSGEL 232
Cdd:PRK11160 475 QLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQ--NKTVLMITHRLTGLEQF-DRICVMDNGQI 551


                 ..
gi 694160455 233 IE 234
Cdd:PRK11160 552 IE 553

CydC

TIGR02868

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...

2-214

2.69e-18

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.

Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 85.49 E-value: 2.69e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    2 TAPLISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPafitGGEVIFNGENILNYS 81
Cdd:TIGR02868 331 GKPTLELRDLSAGY---PGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPL----QGEVTLDGVPVSSLD 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   82 dermqafrwsemsmvfQSAMNALNPVLPMEEQFCDVIMRHT------NMTREQARK--RAEGLLEIVDIHP----SRLTD 149
Cdd:TIGR02868 404 ----------------QDEVRRRVSVCAQDAHLFDTTVRENlrlarpDATDEELWAalERVGLADWLRALPdgldTVLGE 467

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455  150 YPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDL 214
Cdd:TIGR02868 468 GGARLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALS--GRTVVLITHHL 530

cbiO

PRK13647

cobalt transporter ATP-binding subunit; Provisional

6-233

2.87e-18

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 83.25 E-value: 2.87e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPP---AFITGGEVifNGENIlnysd 82
Cdd:PRK13647   5 IEVEDLHFRY---KDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQrgrVKVMGREV--NAENE----- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 ermqafRW--SEMSMVFQSamnalnpvlPMEEQFC-----DVIMRHTNM--TREQARKRAEGLLEIVDIHPSRlTDYPHQ 153
Cdd:PRK13647  75 ------KWvrSKVGLVFQD---------PDDQVFSstvwdDVAFGPVNMglDKDEVERRVEEALKAVRMWDFR-DKPPYH 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:PRK13647 139 LSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVL 217

PRK13536

nodulation factor ABC transporter ATP-binding protein NodI;

1-233

2.99e-18

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 84.11 E-value: 2.99e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYITAA---GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENI 77
Cdd:PRK13536  30 KASIPGSMSTVAIDLAGVSksyGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDA----GKITVLGVPV 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  78 lnysDERMQAFRwSEMSMVFQsaMNALNPVLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGG 157
Cdd:PRK13536 106 ----PARARLAR-ARIGVVPQ--FDNLDLEFTVRENLL-VFGRYFGMSTREIEAVIPSLLEFARLE-SKADARVSDLSGG 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:PRK13536 177 MKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKI 251

PRK10908

cell division ATP-binding protein FtsE;

20-232

3.86e-18

cell division ATP-binding protein FtsE;

Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 81.84 E-value: 3.86e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENILNYSDERMQAFRwSEMSMVFQS 99
Cdd:PRK10908  13 GGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSA----GKIWFSGHDITRLKNREVPFLR-RQIGMIFQD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 AMnalnpvLPMEEQFCDVI---MRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMII 176
Cdd:PRK10908  88 HH------LLMDRTVYDNVaipLIIAGASGDDIRRRVSAALDKVGLL-DKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 177 MDEPTTALDVVVQREILQkiyaLKEEF---GFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK10908 161 ADEPTGNLDDALSEGILR----LFEEFnrvGVTVLMATHDIGLISRRSYRMLTLSDGHL 215

PRK11176

lipid A ABC transporter ATP-binding protein/permease MsbA;

6-243

5.09e-18

lipid A ABC transporter ATP-binding protein/permease MsbA;

Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 84.69 E-value: 5.09e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAagDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafITGGEVIFNGENILNYsdeRM 85
Cdd:PRK11176 342 IEFRNVTFTYPGK--EVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYD----IDEGEILLDGHDLRDY---TL 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQSA--MN---ALNPVLPMEEQFcdvimrhtnmTREQARKRAE-------------GLLEIVDIHPSRL 147
Cdd:PRK11176 413 ASLR-NQVALVSQNVhlFNdtiANNIAYARTEQY----------SREQIEEAARmayamdfinkmdnGLDTVIGENGVLL 481

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 148 tdyphqfSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSlMVEFSDRIGIM 227
Cdd:PRK11176 482 -------SGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKN--RTSLVIAHRLS-TIEKADEILVV 551

                        250
                 ....*....|....*.
gi 694160455 228 YSGELIEVAPSKQILE 243
Cdd:PRK11176 552 EDGEIVERGTHAELLA 567

PRK10895

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

23-242

7.08e-18

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 81.48 E-value: 7.08e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  23 RACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENI----LNYSDERMQAFRWSEMSmVFQ 98
Cdd:PRK10895  17 RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDA----GNIIIDDEDIsllpLHARARRGIGYLPQEAS-IFR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  99 --SAMNALNPVLPMEEqfcdvimrhtNMTREQARKRAEGLLEivDIHPSRLTDYPHQ-FSGGMRQRLVIAIALALNPKMI 175
Cdd:PRK10895  92 rlSVYDNLMAVLQIRD----------DLSAEQREDRANELME--EFHIEHLRDSMGQsLSGGERRRVEIARALAANPKFI 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 176 IMDEPTTALDVVVQREILQKIYALKeEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:PRK10895 160 LLDEPFAGVDPISVIDIKRIIEHLR-DSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEIL 225

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

22-238

8.53e-18

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 83.81 E-value: 8.53e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  22 VRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGEnilnysdermqafrwsemSMVFQSAM 101
Cdd:PRK11288  17 VKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQP----DAGSILIDGQ------------------EMRFASTT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 102 NALN-------------PVLPMEEQfcdvIM------RHTNMTREQARKRAEGLLEI--VDIHPSRLTDYphqFSGGMRQ 160
Cdd:PRK11288  75 AALAagvaiiyqelhlvPEMTVAEN----LYlgqlphKGGIVNRRLLNYEAREQLEHlgVDIDPDTPLKY---LSIGQRQ 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 161 RLVIAIALALNPKMIIMDEPTTALDVvvqREILQ---KIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAP 237
Cdd:PRK11288 148 MVEIAKALARNARVIAFDEPTSSLSA---REIEQlfrVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVATFD 223


                 .
gi 694160455 238 S 238
Cdd:PRK11288 224 D 224

PRK13549

xylose transporter ATP-binding subunit; Provisional

1-243

1.06e-17

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 83.44 E-value: 1.06e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNlcvdyITAA-GDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITG--------GEVI 71
Cdd:PRK13549   1 MMEYLLEMKN-----ITKTfGGVKALDNVSLKVRAGEIVSLCGENGAGKST----LMKV------LSGvyphgtyeGEII 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  72 FNGENIlnysdeRMQAFRWSE---MSMVFQSAMnaLNPVLP-MEEQFC-DVIMRHTNMTREQARKRAEGLLEIV--DIHP 144
Cdd:PRK13549  66 FEGEEL------QASNIRDTEragIAIIHQELA--LVKELSvLENIFLgNEITPGGIMDYDAMYLRAQKLLAQLklDINP 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 145 -SRLTDYphqfsGGMRQRLV-IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSD 222
Cdd:PRK13549 138 aTPVGNL-----GLGQQQLVeIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISD 211

                        250       260
                 ....*....|....*....|.
gi 694160455 223 RIGIMYSGELIEVAPSKQILE 243
Cdd:PRK13549 212 TICVIRDGRHIGTRPAAGMTE 232

CeuD

COG4604

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...

6-245

1.89e-17

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 80.13 E-value: 1.89e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVaFSLM-RLHKPpafiTGGEVIFNGENILNYSDER 84
Cdd:COG4604    2 IEIKNVSKRY----GGKVVLDDVSLTIPKGGITALIGPNGAGKSTL-LSMIsRLLPP----DSGEVLVDGLDVATTPSRE 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MqAFRwseMSMVFQSamNALNPVLPMEEqfcdVIM--R--HT--NMTREQARK--RAEGLLEivdihpsrLTDYPHQF-- 154
Cdd:COG4604   73 L-AKR---LAILRQE--NHINSRLTVRE----LVAfgRfpYSkgRLTAEDREIidEAIAYLD--------LEDLADRYld 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 --SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:COG4604  135 elSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRV 214

                        250
                 ....*....|...
gi 694160455 233 IEVAPSKQILESP 245
Cdd:COG4604  215 VAQGTPEEIITPE 227

cbiO

PRK13640

energy-coupling factor transporter ATPase;

24-245

2.90e-17

energy-coupling factor transporter ATPase;

Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 80.23 E-value: 2.90e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  24 ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPA----FITGGEVIFNGENILNYSDermqafrwsEMSMVFQs 99
Cdd:PRK13640  22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDnpnsKITVDGITLTAKTVWDIRE---------KVGIVFQ- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 amnalNPvlpmEEQFC------DVIMRHTN--MTREQARKRAEGLLEIVDihpsrLTDY----PHQFSGGMRQRLVIAIA 167
Cdd:PRK13640  92 -----NP----DNQFVgatvgdDVAFGLENraVPRPEMIKIVRDVLADVG-----MLDYidsePANLSGGQKQRVAIAGI 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 168 LALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSlMVEFSDRIGIMYSGELIEVAPSKQILESP 245
Cdd:PRK13640 158 LAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDID-EANMADQVLVLDDGKLLAQGSPVEIFSKV 234

cbiO

PRK13644

energy-coupling factor transporter ATPase;

24-260

3.06e-17

energy-coupling factor transporter ATPase;

Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 80.03 E-value: 3.06e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  24 ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENILNYSdeRMQAFRwSEMSMVFQsamna 103
Cdd:PRK13644  17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQK----GKVLVSGIDTGDFS--KLQGIR-KLVGIVFQ----- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 104 lNPvlpmEEQFC------DVIMRHTNMTRE--QARKRAEGLLEIVDIHPSRLTDyPHQFSGGMRQRLVIAIALALNPKMI 175
Cdd:PRK13644  85 -NP----ETQFVgrtveeDLAFGPENLCLPpiEIRKRVDRALAEIGLEKYRHRS-PKTLSGGQGQCVALAGILTMEPECL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 176 IMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMvEFSDRIGIMYSGELIEVAPSKQILESpyhPYTKGLGS 255
Cdd:PRK13644 159 IFDEVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVLSD---VSLQTLGL 233


                 ....*
gi 694160455 256 SFPPL 260
Cdd:PRK13644 234 TPPSL 238

anch_rpt_ABC

TIGR03771

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...

30-262

4.21e-17

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 78.74 E-value: 4.21e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   30 FDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPA--FITGGEVIFNGENILNYSDERMQaFRWSEMSMVFQSAMNALNPV 107
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKgtVKVAGASPGKGWRHIGYVPQRHE-FAWDFPISVAHTVMSGRTGH 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  108 LPMEEQFCDVIMRHTNMTREQARKraeglleivdihpSRLTDYP-HQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDV 186
Cdd:TIGR03771  80 IGWLRRPCVADFAAVRDALRRVGL-------------TELADRPvGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDM 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455  187 VVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIgIMYSGELIEVAPSKQILESPYHPYTKGLGSSFPPLTG 262
Cdd:TIGR03771 147 PTQELLTELFIELAGA-GTAILMTTHDLAQAMATCDRV-VLLNGRVIADGTPQQLQDPAPWMTTFGVSDSSPLLRI 220

PRK13657

glucan ABC transporter ATP-binding protein/ permease;

5-234

6.08e-17

glucan ABC transporter ATP-binding protein/ permease;

Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 81.55 E-value: 6.08e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDER 84
Cdd:PRK13657 334 AVEFDDVSFSY---DNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDP----QSGRILIDGTDI---RTVT 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRWSeMSMVFQSAMnALNPVLpmEEqfcDVIMRHTNMTREQ---ARKRAEGLlEIVDIHPSRLT----DYPHQFSGG 157
Cdd:PRK13657 404 RASLRRN-IAVVFQDAG-LFNRSI--ED---NIRVGRPDATDEEmraAAERAQAH-DFIERKPDGYDtvvgERGRQLSGG 475

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSlMVEFSDRIGIMYSGELIE 234
Cdd:PRK13657 476 ERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELMK--GRTTFIIAHRLS-TVRNADRILVFDNGRVVE 549

cbiO

PRK13645

energy-coupling factor transporter ATPase;

21-244

2.32e-16

energy-coupling factor transporter ATPase;

Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 78.13 E-value: 2.32e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  21 DVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLHKPPAFITGGEVIFnGENILNYSDERMQAFR--WSEMSMVFQ 98
Cdd:PRK13645  23 EFKALNNTSLTFKKNKVTCVIGTTGSGKST----MIQLTNGLIISETGQTIV-GDYAIPANLKKIKEVKrlRKEIGLVFQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  99 samnalnpvLPMEEQFCDVIMR-------HTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALN 171
Cdd:PRK13645  98 ---------FPEYQLFQETIEKdiafgpvNLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMD 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 172 PKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILES 244
Cdd:PRK13645 169 GNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSN 241

btuD

PRK09536

corrinoid ABC transporter ATPase; Reviewed

3-245

2.72e-16

corrinoid ABC transporter ATPase; Reviewed

Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 78.73 E-value: 2.72e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLHKPPAFITGGEVIFNGENILNYSD 82
Cdd:PRK09536   1 MPMIDVSDLSVEF----GDTTVLDGVDLSVREGSLVGLVGPNGAGKTT----LLRAINGTLTPTAGTVLVAGDDVEALSA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 E---RMQAFRWSEMSMVFQSAMNALnpvlpmeeqfcdVIM-RHTNMTR-----EQARKRAEGLLEIVDIhpSRLTDYP-H 152
Cdd:PRK09536  73 RaasRRVASVPQDTSLSFEFDVRQV------------VEMgRTPHRSRfdtwtETDRAAVERAMERTGV--AQFADRPvT 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK09536 139 SLSGGERQRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRV 217

                        250
                 ....*....|...
gi 694160455 233 IEVAPSKQILESP 245
Cdd:PRK09536 218 RAAGPPADVLTAD 230

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

5-243

2.78e-16

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 79.10 E-value: 2.78e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    5 LISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHkpPAFITGGEVIFNGENI----LNY 80
Cdd:TIGR02633   1 LLEMKGIVKTF----GGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVY--PHGTWDGEIYWSGSPLkasnIRD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   81 SDERMQAFRWSEMSMVFQSAMnALNPVLPMEEQFCDVIMRHTNMTReqarkRAEGLLEIVDIHPSRLTDYPHQFSGGMRQ 160
Cdd:TIGR02633  75 TERAGIVIIHQELTLVPELSV-AENIFLGNEITLPGGRMAYNAMYL-----RAKNLLRELQLDADNVTRPVGDYGGGQQQ 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  161 RLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQ 240
Cdd:TIGR02633 149 LVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMST 227


                  ...
gi 694160455  241 ILE 243
Cdd:TIGR02633 228 MSE 230

ABCG_EPDR

cd03213

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...

26-233

8.98e-16

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.

Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 74.51 E-value: 8.98e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfiTGGEVIFNGENIlnysdeRMQAFRwSEMSMVFQsamnaln 105
Cdd:cd03213   26 KNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLG--VSGEVLINGRPL------DKRSFR-KIIGYVPQ------- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 pvlpmEEQFcdvimrHTNMTREQARKRAEGLLEIvdihpsrltdyphqfSGGMRQRLVIAIALALNPKMIIMDEPTTALD 185
Cdd:cd03213   90 -----DDIL------HPTLTVRETLMFAAKLRGL---------------SGGERKRVSIALELVSNPSLLFLDEPTSGLD 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 694160455 186 VVVQREILQKIYALKEEfGFSILFITHDLS-LMVEFSDRIGIMYSGELI 233
Cdd:cd03213  144 SSSALQVMSLLRRLADT-GRTIICSIHQPSsEIFELFDKLLLLSQGRVI 191

PRK10253

iron-enterobactin ABC transporter ATP-binding protein;

1-242

1.04e-15

iron-enterobactin ABC transporter ATP-binding protein;

Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 75.79 E-value: 1.04e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIR--NLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIL 78
Cdd:PRK10253   1 MTESVARLRgeQLTLGY----GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTP----AHGHVWLDGEHIQ 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDERMqAFRWSEMsmvfqsAMNALNPV-LPMEEQFCDVIMRHTNM-TR-----EQARKRAeglleivdIHPSRLTDYP 151
Cdd:PRK10253  73 HYASKEV-ARRIGLL------AQNATTPGdITVQELVARGRYPHQPLfTRwrkedEEAVTKA--------MQATGITHLA 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 HQ----FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIM 227
Cdd:PRK10253 138 DQsvdtLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIAL 217

                        250
                 ....*....|....*
gi 694160455 228 YSGELIEVAPSKQIL 242
Cdd:PRK10253 218 REGKIVAQGAPKEIV 232

cbiO

PRK13643

energy-coupling factor transporter ATPase;

23-243

1.33e-15

energy-coupling factor transporter ATPase;

Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 75.93 E-value: 1.33e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  23 RACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFRWSEMSMVFQsamn 102
Cdd:PRK13643  20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQP----TEGKVTVGDIVVSSTSKQKEIKPVRKKVGVVFQ---- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 103 alnpvLPMEEQFCDVIMRHT-------NMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALNPKMI 175
Cdd:PRK13643  92 -----FPESQLFEETVLKDVafgpqnfGIPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVL 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 176 IMDEPTTALDVVVQREILqKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILE 243
Cdd:PRK13643 167 VLDEPTAGLDPKARIEMM-QLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQ 233

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

6-243

1.39e-15

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 77.15 E-value: 1.39e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSL--MRLHKPpafiTGGEVIFN---------- 73
Cdd:TIGR03269   1 IEVKNLTKKF----DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLrgMDQYEP----TSGRIIYHvalcekcgyv 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   74 ------GEN--------------ILNYSDERMQAFRwSEMSMVFQSAMnalnpVLPMEEQFCDVIMRHTN---MTREQAR 130
Cdd:TIGR03269  73 erpskvGEPcpvcggtlepeevdFWNLSDKLRRRIR-KRIAIMLQRTF-----ALYGDDTVLDNVLEALEeigYEGKEAV 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  131 KRAEGLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFI 210
Cdd:TIGR03269 147 GRAVDLIEMVQLS-HRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLT 225

                         250       260       270
                  ....*....|....*....|....*....|...
gi 694160455  211 THDLSLMVEFSDRIGIMYSGELIEVAPSKQILE 243
Cdd:TIGR03269 226 SHWPEVIEDLSDKAIWLENGEIKEEGTPDEVVA 258

ArpD

COG4618

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...

26-244

1.65e-15

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];

Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 77.10 E-value: 1.65e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERmqafrwsemsmvfqsamnaLN 105
Cdd:COG4618  349 RGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPP----TAGSVRLDGADLSQWDREE-------------------LG 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 PV---LPmeeQfcDV----------IMRHTNMTRE---QARKRAeglleivDIH------P----SRLTDYPHQFSGGMR 159
Cdd:COG4618  406 RHigyLP---Q--DVelfdgtiaenIARFGDADPEkvvAAAKLA-------GVHemilrlPdgydTRIGEGGARLSGGQR 473

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 160 QRlvIAIALAL--NPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEfSDRIGIMYSGELIEVAP 237
Cdd:COG4618  474 QR--IGLARALygDPRLVVLDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRPSLLAA-VDKLLVLRDGRVQAFGP 549


                 ....*..
gi 694160455 238 SKQILES 244
Cdd:COG4618  550 RDEVLAR 556

znuC

PRK09544

high-affinity zinc transporter ATPase; Reviewed

4-224

2.00e-15

high-affinity zinc transporter ATPase; Reviewed

Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 74.77 E-value: 2.00e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDE 83
Cdd:PRK09544   3 SLVSLENVSVSF----GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAP----DEGVIKRNGKLRIGYVPQ 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RMQafrwsemsmvfqsamnaLNPVLPME-EQFcdvimrhtnMTREQARKRAEGLLEIVDIHPSRLTDYPHQ-FSGGMRQR 161
Cdd:PRK09544  75 KLY-----------------LDTTLPLTvNRF---------LRLRPGTKKEDILPALKRVQAGHLIDAPMQkLSGGETQR 128

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRI 224
Cdd:PRK09544 129 VLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEV 191

PRK10247

putative ABC transporter ATP-binding protein YbbL; Provisional

4-213

2.37e-15

putative ABC transporter ATP-binding protein YbbL; Provisional

Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 73.98 E-value: 2.37e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNlcVDYitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDE 83
Cdd:PRK10247   6 PLLQLQN--VGY--LAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISP----TSGTLLFEGEDISTLKPE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 RmqaFRwSEMSMVFQSamnalnPVLPMEEQFCDVIMRHtnMTREQA--RKRAEGLLEIVDIHPSRLTDYPHQFSGGMRQR 161
Cdd:PRK10247  78 I---YR-QQVSYCAQT------PTLFGDTVYDNLIFPW--QIRNQQpdPAIFLDDLERFALPDTILTKNIAELSGGEKQR 145

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHD 213
Cdd:PRK10247 146 ISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHD 197

livF

PRK11614

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

1-233

4.60e-15

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 73.37 E-value: 4.60e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLmrLHKPPAfiTGGEVIFNGENILNY 80
Cdd:PRK11614   1 MEKVMLSFDKVSAHY----GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTL--CGDPRA--TSGRIVFDGKDITDW 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFRWS---EMSMVFQSAMNALNpvLPMEEQFCDvimrhtnmtREQARKRAEgllEIVDIHPsRLTDYPHQ---- 153
Cdd:PRK11614  73 QTAKIMREAVAivpEGRRVFSRMTVEEN--LAMGGFFAE---------RDQFQERIK---WVYELFP-RLHERRIQragt 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:PRK11614 138 MSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVV 216

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

22-241

5.54e-15

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 75.15 E-value: 5.54e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  22 VRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENIlNY--SDERMQafrwSEMSMVFQS 99
Cdd:PRK10982  11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDS----GSILFQGKEI-DFksSKEALE----NGISMVHQE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 amnaLNPVL-------------PMEEQFCDvimrHTNMTREQARKRAEglLEIvDIHPSrltDYPHQFSGGMRQRLVIAI 166
Cdd:PRK10982  82 ----LNLVLqrsvmdnmwlgryPTKGMFVD----QDKMYRDTKAIFDE--LDI-DIDPR---AKVATLSVSQMQMIEIAK 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 167 ALALNPKMIIMDEPTTALdvvVQREI--LQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQI 241
Cdd:PRK10982 148 AFSYNAKIVIMDEPTSSL---TEKEVnhLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAGL 221

hmuV

PRK13547

heme ABC transporter ATP-binding protein;

11-247

6.00e-15

heme ABC transporter ATP-binding protein;

Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 73.71 E-value: 6.00e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  11 LCVDYITAAGDVRAC-NNVSFDIAPGEVFGLAGESGCGKSTV----AFSLMRLHKPPAFITGGEVIFNGENIlnysdERM 85
Cdd:PRK13547   2 LTADHLHVARRHRAIlRDLSLRIEPGRVTALLGRNGAGKSTLlkalAGDLTGGGAPRGARVTGDVTLNGEPL-----AAI 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRWSEMSMVFQSAMNalnPVLPMEEQFCDVIMRHTNMTREQARKRAEG-----LLEIVDIHPSRLTDYPhQFSGGMRQ 160
Cdd:PRK13547  77 DAPRLARLRAVLPQAAQ---PAFAFSAREIVLLGRYPHARRAGALTHRDGeiawqALALAGATALVGRDVT-TLSGGELA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 161 RLVIAIALA---------LNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGE 231
Cdd:PRK13547 153 RVQFARVLAqlwpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGA 232

                        250
                 ....*....|....*.
gi 694160455 232 LIEVAPSKQILeSPYH 247
Cdd:PRK13547 233 IVAHGAPADVL-TPAH 247

bacteriocin_ABC

TIGR01193

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...

27-242

8.53e-15

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]

Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 75.16 E-value: 8.53e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFrwseMSMVFQsamnalNP 106
Cdd:TIGR01193 492 DISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQA----RSGEILLNGFSLKDIDRHTLRQF----INYLPQ------EP 557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  107 VLPMEEQFCDVIMRHTNMTREQARKRAEGLLEI-VDI------HPSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDE 179
Cdd:TIGR01193 558 YIFSGSILENLLLGAKENVSQDEIWAACEIAEIkDDIenmplgYQTELSEEGSSISGGQKQRIALARALLTDSKVLILDE 637

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455  180 PTTALDVVVQREILQKIYALKEEfgfSILFITHDLSLmVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:TIGR01193 638 STSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSV-AKQSDKIIVLDHGKIIEQGSHDELL 696

ycf16

CHL00131

sulfate ABC transporter protein; Validated

1-234

2.04e-14

sulfate ABC transporter protein; Validated

Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 71.60 E-value: 2.04e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVdyitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAfSLMRLHkpPAF-ITGGEVIFNGENILN 79
Cdd:CHL00131   3 KNKPILEIKNLHA----SVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLS-KVIAGH--PAYkILEGDILFKGESILD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 YS-DERMQ-----AFRWS-EMSMV-----FQSAMNA------LNPVLPMEeqFCDVIMRHtnmtreqarkraeglLEIVD 141
Cdd:CHL00131  76 LEpEERAHlgiflAFQYPiEIPGVsnadfLRLAYNSkrkfqgLPELDPLE--FLEIINEK---------------LKLVG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 142 IHPSRLTDYPHQ-FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMvEF 220
Cdd:CHL00131 139 MDPSFLSRNVNEgFSGGEKKRNEILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTS-ENSIILITHYQRLL-DY 216

                        250
                 ....*....|....*.
gi 694160455 221 --SDRIGIMYSGELIE 234
Cdd:CHL00131 217 ikPDYVHVMQNGKIIK 232

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

26-232

4.95e-14

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 72.55 E-value: 4.95e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHkPPAFitGGEVIFNGENIlnysDER--MQAFRwSEMSMVFQSAMN- 102
Cdd:TIGR02633 277 DDVSFSLRRGEILGVAGLVGAGRTELVQALFGAY-PGKF--EGNVFINGKPV----DIRnpAQAIR-AGIAMVPEDRKRh 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  103 --------ALNPVLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIVDIHPsrltDYP-HQFSGGMRQRLVIAIALALNPK 173
Cdd:TIGR02633 349 givpilgvGKNITLSVLKSFC-FKMRIDAAAELQIIGSAIQRLKVKTASP----FLPiGRLSGGNQQKAVLAKMLLTNPR 423

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455  174 MIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:TIGR02633 424 VLILDEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKL 481

PRK10789

SmdA family multidrug ABC transporter permease/ATP-binding protein;

6-245

7.71e-14

SmdA family multidrug ABC transporter permease/ATP-binding protein;

Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 72.05 E-value: 7.71e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCvdYITAagDVRACNNVSFDIAPGEVFGLAGESGCGKSTVaFSLMRLHkppaF-ITGGEVIFNGeniLNYSDER 84
Cdd:PRK10789 316 VNIRQFT--YPQT--DHPALENVNFTLKPGQMLGICGPTGSGKSTL-LSLIQRH----FdVSEGDIRFHD---IPLTKLQ 383

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFRwSEMSMVFQSamnalnPVLpmeeqFCDVIMRHTNMTREQA-RKRAEGLLEIVDIHPS--RLTD-YPHQ------- 153
Cdd:PRK10789 384 LDSWR-SRLAVVSQT------PFL-----FSDTVANNIALGRPDAtQQEIEHVARLASVHDDilRLPQgYDTEvgergvm 451

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEefGFSILFITHDLSLMVEfSDRIGIMYSGELI 233
Cdd:PRK10789 452 LSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWGE--GRTVIISAHRLSALTE-ASEILVMQHGHIA 528

                        250
                 ....*....|..
gi 694160455 234 EVAPSKQILESP 245
Cdd:PRK10789 529 QRGNHDQLAQQS 540

PRK10762

D-ribose transporter ATP binding protein; Provisional

26-232

7.89e-14

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 71.96 E-value: 7.89e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKStvafSLMRLHKPPAFITGGEVIFNGENILNYSDERMQA---FRWSE---------- 92
Cdd:PRK10762 269 NDVSFTLRKGEILGVSGLMGAGRT----ELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLAngiVYISEdrkrdglvlg 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  93 ------MSMV----FQSAMNALNPvlPMEEQFCDVIMRHTNM---TREQARkraeGLLeivdihpsrltdyphqfSGGMR 159
Cdd:PRK10762 345 msvkenMSLTalryFSRAGGSLKH--ADEQQAVSDFIRLFNIktpSMEQAI----GLL-----------------SGGNQ 401

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 160 QRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK10762 402 QKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGRI 473

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

26-230

1.27e-13

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 71.25 E-value: 1.27e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITGGEVIFNGENILNySDERM----QAFRWSEMSMVFQSAM 101
Cdd:COG0488   15 DDVSLSINPGDRIGLVGRNGAGKST----LLKI------LAGELEPDSGEVSIP-KGLRIgylpQEPPLDDDLTVLDTVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 102 NALNPVLPMEEQFCDVIMRHTNMTREQARK-----------------RAEGLLEIVDIHPSRLTDYPHQFSGGMRQRLVI 164
Cdd:COG0488   84 DGDAELRALEAELEELEAKLAEPDEDLERLaelqeefealggweaeaRAEEILSGLGFPEEDLDRPVSELSGGWRRRVAL 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 165 AIALALNPKMIIMDEPTTALDV-VVQ--REILQKiyalkeeFGFSILFITHDLSL-------MVEFSDRIGIMYSG 230
Cdd:COG0488  164 ARALLSEPDLLLLDEPTNHLDLeSIEwlEEFLKN-------YPGTVLVVSHDRYFldrvatrILELDRGKLTLYPG 232

PRK15056

manganese/iron ABC transporter ATP-binding protein;

1-239

1.67e-13

manganese/iron ABC transporter ATP-binding protein;

Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 69.53 E-value: 1.67e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   1 MTAPLISIRNLCVDYITAAGDVRacnNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafITGGEVIFNGENIlny 80
Cdd:PRK15056   2 MQQAGIVVNDVTVTWRNGHTALR---DASFTVPGGSIAALVGVNGSGKSTLFKALMGFVR----LASGKISILGQPT--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 sderMQAFRWSEMSMVFQSA-MNALNPVLpMEeqfcDVIM--RHTNM-----TREQARKRAEGLLEIVDihpsrLTDYPH 152
Cdd:PRK15056  72 ----RQALQKNLVAYVPQSEeVDWSFPVL-VE----DVVMmgRYGHMgwlrrAKKRDRQIVTAALARVD-----MVEFRH 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 153 ----QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIgIMY 228
Cdd:PRK15056 138 rqigELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCDYT-VMV 215

                        250
                 ....*....|.
gi 694160455 229 SGELIEVAPSK 239
Cdd:PRK15056 216 KGTVLASGPTE 226

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

4-224

2.47e-13

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 70.48 E-value: 2.47e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITG------GEVIFnGENI 77
Cdd:COG0488  314 KVLELEGLSKSY----GDKTLLDDLSLRIDRGDRIGLIGPNGAGKST----LLKL------LAGelepdsGTVKL-GETV 378

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  78 -LNYSDERMQAFRwSEMSMVfqsamnalnpvlpmeeqfcDVIMRH-TNMTREQARKRAEGLLeivdIHPSRLTDYPHQFS 155
Cdd:COG0488  379 kIGYFDQHQEELD-PDKTVL-------------------DELRDGaPGGTEQEVRGYLGRFL----FSGDDAFKPVGVLS 434

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 156 GGMRQRLVIAIALALNPKMIIMDEPTTALDVVVqREILQKiyALkEEFGFSILFITHDLSLMVEFSDRI 224
Cdd:COG0488  435 GGEKARLALAKLLLSPPNVLLLDEPTNHLDIET-LEALEE--AL-DDFPGTVLLVSHDRYFLDRVATRI 499

thiQ

TIGR01277

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...

29-232

2.74e-13

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]

Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 67.96 E-value: 2.74e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   29 SFDIAPGEVFGLAGESGCGKSTVaFSLMRLHKPPAfitGGEVIFNGENILNYSDERmqafrwSEMSMVFQSamNALNPVL 108
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTL-LNLIAGFIEPA---SGSIKVNDQSHTGLAPYQ------RPVSMLFQE--NNLFAHL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  109 PMEEQFCDVIMRHTNMTREQARKraeglleIVDIHPSR-LTDY----PHQFSGGMRQRLVIAIALALNPKMIIMDEPTTA 183
Cdd:TIGR01277  86 TVRQNIGLGLHPGLKLNAEQQEK-------VVDAAQQVgIADYldrlPEQLSGGQRQRVALARCLVRPNPILLLDEPFSA 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 694160455  184 LDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:TIGR01277 159 LDPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKI 207

ABC_ThiQ_thiamine_transporter

cd03298

ATP-binding cassette domain of the thiamine transport system; Part of the ...

27-212

3.27e-13

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 67.52 E-value: 3.27e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFD--IAPGEVFGLAGESGCGKSTvafsLMRLhkppafITGGEVIFNGENILNYSDerMQAFRWSE--MSMVFQSamN 102
Cdd:cd03298   14 PMHFDltFAQGEITAIVGPSGSGKST----LLNL------IAGFETPQSGRVLINGVD--VTAAPPADrpVSMLFQE--N 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 103 ALNPVLPMEeQFCDVIMRHTNMTREQARKRAEGLLEIVDIHpSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTT 182
Cdd:cd03298   80 NLFAHLTVE-QNVGLGLSPGLKLTAEDRQAIEVALARVGLA-GLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFA 157

                        170       180       190
                 ....*....|....*....|....*....|
gi 694160455 183 ALDVVVQREILQKIYALKEEFGFSILFITH 212
Cdd:cd03298  158 ALDPALRAEMLDLVLDLHAETKMTVLMVTH 187

thiQ

PRK10771

thiamine ABC transporter ATP-binding protein ThiQ;

29-214

8.72e-13

thiamine ABC transporter ATP-binding protein ThiQ;

Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 66.91 E-value: 8.72e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  29 SFDIAPGEVFGLAGESGCGKSTVaFSLMRLHKPPAfitGGEVIFNGENILNYSDERmqafrwSEMSMVFQSamNALNPVL 108
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTL-LNLIAGFLTPA---SGSLTLNGQDHTTTPPSR------RPVSMLFQE--NNLFSHL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 109 PMEEQF---CDVIMRHTNMTREQARKRAE--GLLEIVDihpsRLtdyPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTA 183
Cdd:PRK10771  87 TVAQNIglgLNPGLKLNAAQREKLHAIARqmGIEDLLA----RL---PGQLSGGQRQRVALARCLVREQPILLLDEPFSA 159

                        170       180       190
                 ....*....|....*....|....*....|.
gi 694160455 184 LDVVVQREILQKIYALKEEFGFSILFITHDL 214
Cdd:PRK10771 160 LDPALRQEMLTLVSQVCQERQLTLLMVSHSL 190

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

20-231

1.16e-12

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 68.61 E-value: 1.16e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVafslMrlhK------PP----AFITGGEVifNGENIlnysDERM---- 85
Cdd:NF033858 277 GDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTT----M---KmltgllPAsegeAWLFGQPV--DAGDI----ATRRrvgy 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 --QAFR-WSEMSmVFQsamnalNPVLpmeeqfcdvimrHT---NMTREQARKRAEGLLEIVDihpsrLTDYPHQFSG--- 156
Cdd:NF033858 344 msQAFSlYGELT-VRQ------NLEL------------HArlfHLPAAEIAARVAEMLERFD-----LADVADALPDslp 399

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 157 -GMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSIlFI-THdlsLMVEFS--DRIGIMYSGE 231
Cdd:NF033858 400 lGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTI-FIsTH---FMNEAErcDRISLMHAGR 474

ABCF_EF-3

cd03221

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...

26-224

1.83e-12

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.

Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 64.01 E-value: 1.83e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITGGEVIFNGenilnysdermqafrwsemsmvfqsamnaln 105
Cdd:cd03221   17 KDISLTINPGDRIGLVGRNGAGKST----LLKL------IAGELEPDEG------------------------------- 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 pvlpmeeqfcdvimrhtnmtreqarkraeglleIVDIHPSRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALD 185
Cdd:cd03221   56 ---------------------------------IVTWGSTVKIGYFEQLSGGEKMRLALAKLLLENPNLLLLDEPTNHLD 102

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 694160455 186 vVVQREILQKiyALKeEFGFSILFITHDLSLMVEFSDRI 224
Cdd:cd03221  103 -LESIEALEE--ALK-EYPGTVILVSHDRYFLDQVATKI 137

BtuD

COG4138

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...

28-242

1.97e-12

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];

Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 66.02 E-value: 1.97e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  28 VSFDIAPGEVFGLAGESGCGKSTVafsLMRLhkppA-FITG-GEVIFNGENILNYSDERMQAFRwsemSMVFQSAMNALN 105
Cdd:COG4138   15 ISAQVNAGELIHLIGPNGAGKSTL---LARM----AgLLPGqGEILLNGRPLSDWSAAELARHR----AYLSQQQSPPFA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 -----------PVLPMEEQFCDVIMRHTnmtreqarkraeGLLEIVDIHPSRLTdyphQFSGGMRQRLVIAIAL-----A 169
Cdd:COG4138   84 mpvfqylalhqPAGASSEAVEQLLAQLA------------EALGLEDKLSRPLT----QLSGGEWQRVRLAAVLlqvwpT 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 170 LNP--KMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQIL 242
Cdd:COG4138  148 INPegQLLLLDEPMNSLDVAQQAALDRLLRELCQQ-GITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVM 221

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

21-235

2.11e-12

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 67.50 E-value: 2.11e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  21 DVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafITGGEVIFNGENIL---------------------- 78
Cdd:PRK09700 275 DRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDK----RAGGEIRLNGKDISprspldavkkgmayitesrrdn 350

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 ----NYSDERMQAFRWSEMSMVFQSAMNALNPVlpmEEQfcdvimrhtnmtreqarKRAEGLLEIVDIHPSRLTDYPHQF 154
Cdd:PRK09700 351 gffpNFSIAQNMAISRSLKDGGYKGAMGLFHEV---DEQ-----------------RTAENQRELLALKCHSVNQNITEL 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:PRK09700 411 SGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489


                 .
gi 694160455 235 V 235
Cdd:PRK09700 490 I 490

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

27-232

2.13e-12

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 68.12 E-value: 2.13e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    27 NVSFdiAPGEVFGLAGESGCGKSTVaFSLMRLHKPPafiTGGEVIFNGENIlnysDERMQAFRWSeMSMVFQSamNALNP 106
Cdd:TIGR01257  950 NITF--YENQITAFLGHNGAGKTTT-LSILTGLLPP---TSGTVLVGGKDI----ETNLDAVRQS-LGMCPQH--NILFH 1016

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   107 VLPMEEQfcdvIMRHTNM---TREQARKRAEGLLEIVDIHPSRlTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTA 183
Cdd:TIGR01257 1017 HLTVAEH----ILFYAQLkgrSWEEAQLEMEAMLEDTGLHHKR-NEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSG 1091

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 694160455   184 LDVVVQREILQKIyaLKEEFGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:TIGR01257 1092 VDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRL 1138

ATM1

COG5265

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...

26-234

2.17e-12

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 67.54 E-value: 2.17e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAfrwsEMSMVFQsamnalN 105
Cdd:COG5265  375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDV----TSGRILIDGQDIRDVTQASLRA----AIGIVPQ------D 440

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 PVLpmeeqFCDVIM------RhTNMTREQARKRAEglleIVDIHP--SRLtdyPHQF-----------SGGMRQRlvIAI 166
Cdd:COG5265  441 TVL-----FNDTIAyniaygR-PDASEEEVEAAAR----AAQIHDfiESL---PDGYdtrvgerglklSGGEKQR--VAI 505

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 167 ALAL--NPKMIIMDEPTTALDVVVQREILQkiyALKE-EFGFSILFITHDLSLMVEfSDRIGIMYSGELIE 234
Cdd:COG5265  506 ARTLlkNPPILIFDEATSALDSRTERAIQA---ALREvARGRTTLVIAHRLSTIVD-ADEILVLEAGRIVE 572

ugpC

PRK11650

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

6-230

2.30e-12

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 66.79 E-value: 2.30e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHKppafITGGEVIFNGENIlnys 81
Cdd:PRK11650   4 LKLQAVRKSY---DGKTQVIKGIDLDVADGEFIVLVGPSGCGKST----LLRmvagLER----ITSGEIWIGGRVV---- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  82 DERMQAFRwsEMSMVFQsamN-ALNPVLPMEEQfcdviM----RHTNMTREQARKR---AEGLLEIVDIhpsrLTDYPHQ 153
Cdd:PRK11650  69 NELEPADR--DIAMVFQ---NyALYPHMSVREN-----MayglKIRGMPKAEIEERvaeAARILELEPL----LDRKPRE 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALD----VVVQREILQkiyaLKEEFGFSILFITHDlslMVE---FSDRIGI 226
Cdd:PRK11650 135 LSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDaklrVQMRLEIQR----LHRRLKTTSLYVTHD---QVEamtLADRVVV 207


                 ....
gi 694160455 227 MYSG 230
Cdd:PRK11650 208 MNGG 211

ccmA

TIGR01189

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...

27-212

2.40e-12

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]

Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 64.69 E-value: 2.40e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERMQAFRWSemsmvfqSAMNALNP 106
Cdd:TIGR01189  18 GLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRP----DSGEVRWNGTPLAEQRDEPHENILYL-------GHLPGLKP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  107 VLPMEE--QFCDVIMRHTNMTREQArkraeglLEIVDIhpSRLTDYP-HQFSGGMRQRLVIAIALALNPKMIIMDEPTTA 183
Cdd:TIGR01189  87 ELSALEnlHFWAAIHGGAQRTIEDA-------LAAVGL--TGFEDLPaAQLSAGQQRRLALARLWLSRRPLWILDEPTTA 157

                         170       180
                  ....*....|....*....|....*....
gi 694160455  184 LDVVVQrEILQKIYALKEEFGFSILFITH 212
Cdd:TIGR01189 158 LDKAGV-ALLAGLLRAHLARGGIVLLTTH 185

PTZ00265

multidrug resistance protein (mdr1); Provisional

6-231

2.80e-12

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 67.75 E-value: 2.80e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    6 ISIRNLCVDYITAAgDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENilNYSDERM 85
Cdd:PTZ00265  383 IQFKNVRFHYDTRK-DVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDP----TEGDIIINDSH--NLKDINL 455

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   86 QAFRwSEMSMVFQS--------------AMNALNPVLPMEEQ-------------------------FCDVIMRHTNMTR 126
Cdd:PTZ00265  456 KWWR-SKIGVVSQDpllfsnsiknnikySLYSLKDLEALSNYynedgndsqenknkrnscrakcagdLNDMSNTTDSNEL 534

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  127 EQARKRAEGL--LEIVD------IHP--SRLTDY--------PHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVV 188
Cdd:PTZ00265  535 IEMRKNYQTIkdSEVVDvskkvlIHDfvSALPDKyetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKS 614

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 694160455  189 QREILQKIYALKEEFGFSILFITHDLSlMVEFSDRIGIMYSGE 231
Cdd:PTZ00265  615 EYLVQKTINNLKGNENRITIIIAHRLS-TIRYANTIFVLSNRE 656

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

4-230

2.93e-12

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 67.00 E-value: 2.93e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLH---KPPafiTGGEVIFNGENILNY 80
Cdd:PRK15439  10 PLLCARSISKQY----SGVEVLKGIDFTLHAGEVHALLGGNGAGKST----LMKIIagiVPP---DSGTLEIGGNPCARL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  81 SDERMQAFrwsEMSMVFQSAMnaLNPVLPMEEQFCDVIMRHTNMTREQARKRAE-----------GLLEIVDihpsrltd 149
Cdd:PRK15439  79 TPAKAHQL---GIYLVPQEPL--LFPNLSVKENILFGLPKRQASMQKMKQLLAAlgcqldldssaGSLEVAD-------- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 150 yphqfsggmRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYS 229
Cdd:PRK15439 146 ---------RQIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRD 215


                 .
gi 694160455 230 G 230
Cdd:PRK15439 216 G 216

GguA

NF040905

sugar ABC transporter ATP-binding protein;

22-234

3.79e-12

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 66.74 E-value: 3.79e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  22 VRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMR----LHkpPAFITGGEVIFNGEnILNYSDermqaFRWSE---MS 94
Cdd:NF040905  14 VKALDDVNLSVREGEIHALCGENGAGKST----LMKvlsgVY--PHGSYEGEILFDGE-VCRFKD-----IRDSEalgIV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  95 MVFQSAmnALNPVLPMEEqfcdvimrhtNM--TREQAR----------KRAEGLLEIV--DIHPS-RLTDYphqfsGGMR 159
Cdd:NF040905  82 IIHQEL--ALIPYLSIAE----------NIflGNERAKrgvidwnetnRRARELLAKVglDESPDtLVTDI-----GVGK 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 160 QRLV-IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILfITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:NF040905 145 QQLVeIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSII-ISHKLNEIRRVADSITVLRDGRTIE 219

PRK10762

D-ribose transporter ATP binding protein; Provisional

22-233

4.75e-12

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 66.57 E-value: 4.75e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  22 VRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITG------GEVIFNGENILNYSDERMQAfrwSEMSM 95
Cdd:PRK10762  17 VKALSGAALNVYPGRVMALVGENGAGKST----MMKV------LTGiytrdaGSILYLGKEVTFNGPKSSQE---AGIGI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  96 VFQSamnaLN--PVLPMEE------QFCDVIMR--HTNMTREqarkrAEGLLEIVDI--HPSRLTDyphQFSGGMRQRLV 163
Cdd:PRK10762  84 IHQE----LNliPQLTIAEniflgrEFVNRFGRidWKKMYAE-----ADKLLARLNLrfSSDKLVG---ELSIGEQQMVE 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:PRK10762 152 IAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDGQFI 220

type_I_sec_PrtD

TIGR01842

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...

13-242

8.29e-12

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 65.83 E-value: 8.29e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   13 VDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERmqafrwse 92
Cdd:TIGR01842 322 VTIVPPGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPP----TSGSVRLDGADLKQWDRET-------- 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   93 msmvfqsamnaLNP---VLPMEEQFCD-----VIMRHT-NMTREQ--ARKRAEGLLEIV----DIHPSRLTDYPHQFSGG 157
Cdd:TIGR01842 390 -----------FGKhigYLPQDVELFPgtvaeNIARFGeNADPEKiiEAAKLAGVHELIlrlpDGYDTVIGPGGATLSGG 458

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  158 MRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMvEFSDRIGIMYSGELIEVAP 237
Cdd:TIGR01842 459 QRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKAR-GITVVVITHRPSLL-GCVDKILVLQDGRIARFGE 536


                  ....*
gi 694160455  238 SKQIL 242
Cdd:TIGR01842 537 RDEVL 541

PLN03232

ABC transporter C family member; Provisional

28-258

8.63e-12

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 66.15 E-value: 8.63e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   28 VSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafITGGEVIFNGENILNY--SDERmqafrwSEMSMVFQSamnaln 105
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVE----LEKGRIMIDDCDVAKFglTDLR------RVLSIIPQS------ 1318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  106 PVL-PMEEQF-CDVIMRHTNMTREQARKRAEgLLEIVDIHP----SRLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDE 179
Cdd:PLN03232 1319 PVLfSGTVRFnIDPFSEHNDADLWEALERAH-IKDVIDRNPfgldAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDE 1397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  180 PTTALDVVVQREILQKIyalKEEF-GFSILFITHDLSLMVEfSDRIGIMYSGELIEVAPSKQILESPYHPYTKGLGSSFP 258
Cdd:PLN03232 1398 ATASVDVRTDSLIQRTI---REEFkSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRDTSAFFRMVHSTGP 1473

PRK10790

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

6-244

1.06e-11

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 65.51 E-value: 1.06e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAfSLMRLHKPPafiTGGEVIFNGENILNYSDerm 85
Cdd:PRK10790 341 IDIDNVSFAY---RDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLA-SLLMGYYPL---TEGEIRLDGRPLSSLSH--- 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQsamnalNPVLpMEEQFCDVIMRHTNMTREQ-------------ARKRAEGlleivdIHpSRLTDYPH 152
Cdd:PRK10790 411 SVLR-QGVAMVQQ------DPVV-LADTFLANVTLGRDISEEQvwqaletvqlaelARSLPDG------LY-TPLGEQGN 475

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfgFSILFITHDLSLMVEfSDRIGIMYSGEL 232
Cdd:PRK10790 476 NLSVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREH--TTLVVIAHRLSTIVE-ADTILVLHRGQA 552

                        250
                 ....*....|..
gi 694160455 233 IEVAPSKQILES 244
Cdd:PRK10790 553 VEQGTHQQLLAA 564

PhnK

COG1101

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

22-233

1.12e-11

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 63.95 E-value: 1.12e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  22 VRACNNVSFDIAPGEVFGLAGESGCGKST----VAFSLMrlhkppafITGGEVIFNGENILNYSDERmqafRWSEMSMVF 97
Cdd:COG1101   19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTllnaIAGSLP--------PDSGSILIDGKDVTKLPEYK----RAKYIGRVF 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  98 QSAMNALNPVLPMEEQFCDVIMRHTNMT---------REQARKRAEGL---LEivdihpSRLTDYPHQFSGGMRQrlvia 165
Cdd:COG1101   87 QDPMMGTAPSMTIEENLALAYRRGKRRGlrrgltkkrRELFRELLATLglgLE------NRLDTKVGLLSGGQRQ----- 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 166 iALAL------NPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:COG1101  156 -ALSLlmatltKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRII 228

PRK13546

teichoic acids export ABC transporter ATP-binding subunit TagH;

24-234

1.26e-11

teichoic acids export ABC transporter ATP-binding subunit TagH;

Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 64.07 E-value: 1.26e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  24 ACNNVSFDIAPGEVFGLAGESGCGKSTVAfSLMRLHKPPafiTGGEVIFNGEnilnysdermqafrwseMSMVfqsAMNA 103
Cdd:PRK13546  39 ALDDISLKAYEGDVIGLVGINGSGKSTLS-NIIGGSLSP---TVGKVDRNGE-----------------VSVI---AISA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 104 -LNPVLPMEEQFcDVIMRHTNMTREQARKRAEGLLEIvdihpSRLTDYPHQ----FSGGMRQRLVIAIALALNPKMIIMD 178
Cdd:PRK13546  95 gLSGQLTGIENI-EFKMLCMGFKRKEIKAMTPKIIEF-----SELGEFIYQpvkkYSSGMRAKLGFSINITVNPDILVID 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 179 EPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIE 234
Cdd:PRK13546 169 EALSVGDQTFAQKCLDKIYEFKEQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKD 223

PRK11174

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

6-234

1.49e-11

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 65.25 E-value: 1.49e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCvdyITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKStvafSLMRLhkppafITG-----GEVIFNGE--NIL 78
Cdd:PRK11174 350 IEAEDLE---ILSPDGKTLAGPLNFTLPAGQRIALVGPSGAGKT----SLLNA------LLGflpyqGSLKINGIelREL 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 NYSDERMQafrwseMSMVFQsamnalNPVLPMEEQFCDVIMRHTNMTREQ---ARKRAeGLLEIVDIHPSRLtDYPHQ-- 153
Cdd:PRK11174 417 DPESWRKH------LSWVGQ------NPQLPHGTLRDNVLLGNPDASDEQlqqALENA-WVSEFLPLLPQGL-DTPIGdq 482

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 154 ---FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQkiyALKEE-FGFSILFITHDLSLMVEFsDRIGIMYS 229
Cdd:PRK11174 483 aagLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLVMQ---ALNAAsRRQTTLMVTHQLEDLAQW-DQIWVMQD 558


                 ....*
gi 694160455 230 GELIE 234
Cdd:PRK11174 559 GQIVQ 563

ABC_RNaseL_inhibitor_domain1

cd03236

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

33-228

1.84e-11

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 63.15 E-value: 1.84e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  33 APGEVFGLAGESGCGKSTVAFslmrlhkppafITGGEVIfngENILNYS-----DERMQAFRWSEMSMVFQSAMNA-LNP 106
Cdd:cd03236   24 REGQVLGLVGPNGIGKSTALK-----------ILAGKLK---PNLGKFDdppdwDEILDEFRGSELQNYFTKLLEGdVKV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 107 VlpMEEQFCDVIMRHT------NMTREQARKRAEGLLEIVDIHP--SRLTDyphQFSGGMRQRLVIAIALALNPKMIIMD 178
Cdd:cd03236   90 I--VKPQYVDLIPKAVkgkvgeLLKKKDERGKLDELVDQLELRHvlDRNID---QLSGGELQRVAIAAALARDADFYFFD 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 694160455 179 EPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMY 228
Cdd:cd03236  165 EPSSYLDIKQRLNAARLIRELAED-DNYVLVVEHDLAVLDYLSDYIHCLY 213

modC

PRK11144

molybdenum ABC transporter ATP-binding protein ModC;

147-245

2.06e-11

molybdenum ABC transporter ATP-binding protein ModC;

Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 64.13 E-value: 2.06e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 147 LTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGI 226
Cdd:PRK11144 122 LDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVV 201

                         90
                 ....*....|....*....
gi 694160455 227 MYSGELIEVAPSKQILESP 245
Cdd:PRK11144 202 LEQGKVKAFGPLEEVWASS 220

PRK10522

multidrug transporter membrane component/ATP-binding component; Provisional

6-234

3.96e-11

multidrug transporter membrane component/ATP-binding component; Provisional

Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 63.84 E-value: 3.96e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVracNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENIlnySDERM 85
Cdd:PRK10522 323 LELRNVTFAYQDNGFSV---GPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQS----GEILLDGKPV---TAEQP 392

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFqSAMNALNPVL-----PMEEQFCDVIMRHTNMTREqarkraeglLEIVDihpSRLTDYphQFSGGMRQ 160
Cdd:PRK10522 393 EDYR-KLFSAVF-TDFHLFDQLLgpegkPANPALVEKWLERLKMAHK---------LELED---GRISNL--KLSKGQKK 456

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 161 RLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDlSLMVEFSDRIGIMYSGELIE 234
Cdd:PRK10522 457 RLALLLALAEERDILLLDEWAADQDPHFRREFYQVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQLSE 529

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

20-216

5.38e-11

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 60.71 E-value: 5.38e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILNYSDERmqafrwsemsmvfqs 99
Cdd:NF040873   3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRP----TSGTVRRAGGARVAYVPQR--------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 100 amNALNPVLPMEEQFCdVIM---RHTNMTRE---QARKRAEGLLEIVDIHpsRLTDYP-HQFSGGMRQRLVIAIALALNP 172
Cdd:NF040873  64 --SEVPDSLPLTVRDL-VAMgrwARRGLWRRltrDDRAAVDDALERVGLA--DLAGRQlGELSGGQRQRALLAQGLAQEA 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 694160455 173 KMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSL 216
Cdd:NF040873 139 DLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLEL 181

ABC_RNaseL_inhibitor_domain2

cd03237

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

31-245

6.92e-11

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 61.66 E-value: 6.92e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  31 DIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnysdermqAFRWSEMSMVFQSAMNALnpvlpm 110
Cdd:cd03237   21 SISESEVIGILGPNGIGKTTFIKMLAGVLKP----DEGDIEIELDTV---------SYKPQYIKADYEGTVRDL------ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 111 eeqFCDVIMRHTnmTREQARKRAEGLLEIVDIHPSRLTDyphqFSGGMRQRLVIAIALALNPKMIIMDEPTTALDvVVQR 190
Cdd:cd03237   82 ---LSSITKDFY--THPYFKTEIAKPLQIEQILDREVPE----LSGGELQRVAIAACLSKDADIYLLDEPSAYLD-VEQR 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 191 EILQKI---YALKEEFGfsILFITHDLSLMVEFSDRIgIMYSGElievaPSKQILESP 245
Cdd:cd03237  152 LMASKVirrFAENNEKT--AFVVEHDIIMIDYLADRL-IVFEGE-----PSVNGVANP 201

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

28-232

6.92e-11

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 63.01 E-value: 6.92e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  28 VSFDIAPGEVFGLAGESGCGKStvafSLMRLHKPPAFITGGEVIFNGENIlnysdermqafrwsemsmVFQSAMNALN-- 105
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRS----ELMKLLYGATRRTAGQVYLDGKPI------------------DIRSPRDAIRag 329

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 --------------PVLPMEEQFCDVIMRHTNMTREQARKRAEGllEIVDIHPSRL---TDYPHQ----FSGGMRQRLVI 164
Cdd:PRK11288 330 imlcpedrkaegiiPVHSVADNINISARRHHLRAGCLINNRWEA--ENADRFIRSLnikTPSREQlimnLSGGNQQKAIL 407

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 165 AIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK11288 408 GRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQ-GVAVLFVSSDLPEVLGVADRIVVMREGRI 474

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

24-230

7.11e-11

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 63.49 E-value: 7.11e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    24 ACNNVSFDIAPGEVFGLAGESGCGKSTVafslMRLHKPPAFITGGEVIFNGENILNYSDERMQafrwsemSMVFQSAMNA 103
Cdd:TIGR01257 1954 AVDRLCVGVRPGECFGLLGVNGAGKTTT----FKMLTGDTTVTSGDATVAGKSILTNISDVHQ-------NMGYCPQFDA 2022

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   104 LNPVLPMEEQFCdVIMRHTNMTREQARKRAEGLLEIV--DIHPSRLTDyphQFSGGMRQRLVIAIALALNPKMIIMDEPT 181
Cdd:TIGR01257 2023 IDDLLTGREHLY-LYARLRGVPAEEIEKVANWSIQSLglSLYADRLAG---TYSGGNKRKLSTAIALIGCPPLVLLDEPT 2098

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 694160455   182 TALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSG 230
Cdd:TIGR01257 2099 TGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKG 2146

tagH

PRK13545

teichoic acids export protein ATP-binding subunit; Provisional

24-252

7.74e-11

teichoic acids export protein ATP-binding subunit; Provisional

Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 62.99 E-value: 7.74e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  24 ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENILnysdermqafrwsemsMVFQSAMNa 103
Cdd:PRK13545  39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMP----NKGTVDIKGSAAL----------------IAISSGLN- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 104 lNPVLPMEEQFCDVIMrhTNMTREQARKRAEGLLEIVDIhpSRLTDYP-HQFSGGMRQRLVIAIALALNPKMIIMDEPTT 182
Cdd:PRK13545  98 -GQLTGIENIELKGLM--MGLTKEKIKEIIPEIIEFADI--GKFIYQPvKTYSSGMKSRLGFAISVHINPDILVIDEALS 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 183 ALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILESpYHPYTKG 252
Cdd:PRK13545 173 VGDQTFTKKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDH-YDEFLKK 240

PTZ00243

ABC transporter; Provisional

26-256

1.01e-10

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 62.87 E-value: 1.01e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafITGGEVIFNGENILNYS-DERMQAFrwsemSMVFQsamnal 104
Cdd:PTZ00243 1327 RGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVE----VCGGEIRVNGREIGAYGlRELRRQF-----SMIPQ------ 1391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  105 NPVL----------PMEEQFCDVIMRHTNMT--REQARKRAEGLleivdihPSRLTDYPHQFSGGMRQRLVIAIA-LALN 171
Cdd:PTZ00243 1392 DPVLfdgtvrqnvdPFLEASSAEVWAALELVglRERVASESEGI-------DSRVLEGGSNYSVGQRQLMCMARAlLKKG 1464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  172 PKMIIMDEPTTALDVVVQREILQKIYAlkeefGFS---ILFITHDLSLMVEFsDRIGIMYSGELIEVAPSKQILESP--- 245
Cdd:PTZ00243 1465 SGFILMDEATANIDPALDRQIQATVMS-----AFSaytVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSPRELVMNRqsi 1538

                         250
                  ....*....|.
gi 694160455  246 YHPYTKGLGSS 256
Cdd:PTZ00243 1539 FHSMVEALGRS 1549

PRK13549

xylose transporter ATP-binding subunit; Provisional

155-232

1.04e-10

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 62.25 E-value: 1.04e-10

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK13549 407 SGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGKL 483

YddA

COG4178

ABC-type uncharacterized transport system, permease and ATPase components [General function ...

6-224

1.38e-10

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];

Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 62.13 E-value: 1.38e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDyiTAAGDVRAcNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRlhkppAfITG------GEVIF-NGENIL 78
Cdd:COG4178  363 LALEDLTLR--TPDGRPLL-EDLSLSLKPGERLLITGPSGSGKST----LLR-----A-IAGlwpygsGRIARpAGARVL 429

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  79 ------------------------NYSDERMQAfrwsemsmvfqsAMNALNpvLPmeeqfcdvimrhtnmtreqarkrae 134
Cdd:COG4178  430 flpqrpylplgtlreallypataeAFSDAELRE------------ALEAVG--LG------------------------- 470

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 135 GLLEIVDIHpsrlTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQkiyALKEEF-GFSILFITHD 213
Cdd:COG4178  471 HLAERLDEE----ADWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQ---LLREELpGTTVISVGHR 543

                        250
                 ....*....|.
gi 694160455 214 LSLMvEFSDRI 224
Cdd:COG4178  544 STLA-AFHDRV 553

PRK13540

cytochrome c biogenesis protein CcmA; Provisional

5-216

1.62e-10

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 59.58 E-value: 1.62e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENIlnysDER 84
Cdd:PRK13540   1 MLDVIELDFDY----HDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEK----GEILFERQSI----KKD 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 MQAFrwsEMSMVFQSAMNALNPVLPMEEQ-FCDVIMRHTNMtreqarkraeGLLEIVDIHP-SRLTDYP-HQFSGGMRQR 161
Cdd:PRK13540  69 LCTY---QKQLCFVGHRSGINPYLTLRENcLYDIHFSPGAV----------GITELCRLFSlEHLIDYPcGLLSSGQKRQ 135

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 162 LVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSL 216
Cdd:PRK13540 136 VALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQEHRAKGGAVLLTSHQDLPL 190

PRK09984

phosphonate ABC transporter ATP-binding protein;

23-240

2.15e-10

phosphonate ABC transporter ATP-binding protein;

Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 60.41 E-value: 2.15e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  23 RACNNVSFDIAPGEVFGLAGESGCGKSTVafslmrLHKPPAFITGGEVIFNGENILNYSDER----MQAFRWS--EMSMV 96
Cdd:PRK09984  18 QALHAVDLNIHHGEMVALLGPSGSGKSTL------LRHLSGLITGDKSAGSHIELLGRTVQRegrlARDIRKSraNTGYI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  97 FQSaMNALNPVLPMEE---------QFCDVIMRHtnMTREQARKRAEGLLEIVDIHpsrltdYPHQ----FSGGMRQRLV 163
Cdd:PRK09984  92 FQQ-FNLVNRLSVLENvligalgstPFWRTCFSW--FTREQKQRALQALTRVGMVH------FAHQrvstLSGGQQQRVA 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 164 IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQ 240
Cdd:PRK09984 163 IARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQ 239

3a01204

TIGR00955

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...

26-307

2.60e-10

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 61.22 E-value: 2.60e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLhKPPAFITGGEVIFNGENILNYSDERMQAFrwsemsmVFQSAMNAln 105
Cdd:TIGR00955  42 KNVSGVAKPGELLAVMGSSGAGKTTLMNALAFR-SPKGVKGSGSVLLNGMPIDAKEMRAISAY-------VQQDDLFI-- 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  106 PVLPMEEQFcdVIMRHTNM----TREQARKRAEGLLEIVDIHPSRLT-----DYPHQFSGGMRQRLVIAIALALNPKMII 176
Cdd:TIGR00955 112 PTLTVREHL--MFQAHLRMprrvTKKEKRERVDEVLQALGLRKCANTrigvpGRVKGLSGGERKRLAFASELLTDPPLLF 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  177 MDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLS--LMVEFsDRIGIMYSGELIevapskqILESPYH--PYTKG 252
Cdd:TIGR00955 190 CDEPTSGLDSFMAYSVVQVLKGLAQK-GKTIICTIHQPSseLFELF-DKIILMAEGRVA-------YLGSPDQavPFFSD 260

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455  253 LGSSFPPLTGPK----TKLTGIPGNplnllEIPQGCRFQARCDrvHEACTKIPTQLKQI 307
Cdd:TIGR00955 261 LGHPCPENYNPAdfyvQVLAVIPGS-----ENESRERIEKICD--SFAVSDIGRDMLVN 312

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

20-233

3.03e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 60.52 E-value: 3.03e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  20 GDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFslmrlhkpPAFITGGEvifngenilnySDERMQAFR-WSEMSMVFQ 98
Cdd:NF000106  24 GEVKAVDGVDLDVREGTVLGVLGP*GAA**RGAL--------PAHV*GPD-----------AGRRPWRF*tWCANRRALR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  99 SAMNALNPVLP-MEEQFCD-----VIMRHTNMTREQARKRAEGLLEIVDIHPSRlTDYPHQFSGGMRQRLVIAIALALNP 172
Cdd:NF000106  85 RTIG*HRPVR*gRRESFSGrenlyMIGR*LDLSRKDARARADELLERFSLTEAA-GRAAAKYSGGMRRRLDLAASMIGRP 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 694160455 173 KMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:NF000106 164 AVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVI 223

PLN03130

ABC transporter C family member; Provisional

28-234

7.32e-10

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 60.14 E-value: 7.32e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   28 VSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENILNY--SDERmqafrwSEMSMVFQSamnaln 105
Cdd:PLN03130 1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELER----GRILIDGCDISKFglMDLR------KVLGIIPQA------ 1321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  106 PVL----------PMEEqfcdvimrHTNMTREQARKRAEgLLEIVDIHP----SRLTDYPHQFSGGMRQRLVIAIALALN 171
Cdd:PLN03130 1322 PVLfsgtvrfnldPFNE--------HNDADLWESLERAH-LKDVIRRNSlgldAEVSEAGENFSVGQRQLLSLARALLRR 1392

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455  172 PKMIIMDEPTTALDVVVQrEILQKiyALKEEF-GFSILFITHDLSLMVEfSDRIGIMYSGELIE 234
Cdd:PLN03130 1393 SKILVLDEATAAVDVRTD-ALIQK--TIREEFkSCTMLIIAHRLNTIID-CDRILVLDAGRVVE 1452

PRK03695

vitamin B12-transporter ATPase; Provisional

28-233

8.23e-10

vitamin B12-transporter ATPase; Provisional

Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 58.41 E-value: 8.23e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  28 VSFDIAPGEVFGLAGESGCGKSTVafslmrLHKPPAFITG-GEVIFNGENILNYSD---ERMQAFRWSEMSMVFqsAMna 103
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTL------LARMAGLLPGsGSIQFAGQPLEAWSAaelARHRAYLSQQQTPPF--AM-- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 104 lnPVLpmeeQFCDvIMRHTNMTREQARKRAEGLLEIVdihpsRLTDYPH----QFSGGMRQRLVIAIAL-----ALNP-- 172
Cdd:PRK03695  85 --PVF----QYLT-LHQPDKTRTEAVASALNEVAEAL-----GLDDKLGrsvnQLSGGEWQRVRLAAVVlqvwpDINPag 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 173 KMIIMDEPTTALDvVVQREILqkiYALKEEF---GFSILFITHDLSLMVEFSDRIGIMYSGELI 233
Cdd:PRK03695 153 QLLLLDEPMNSLD-VAQQAAL---DRLLSELcqqGIAVVMSSHDLNHTLRHADRVWLLKQGKLL 212

ABCC_SUR2

cd03288

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...

6-234

1.56e-09

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 57.61 E-value: 1.56e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVraCNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLhkppAFITGGEVIFNGENIlnySDERM 85
Cdd:cd03288   20 IKIHDLCVRYENNLKPV--LKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRM----VDIFDGKIVIDGIDI---SKLPL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRwSEMSMVFQsamnalNPVLpmeeqFCDVIMRHTNMTREQARKRAEGLLEIVDIH------PSRL----TDYPHQFS 155
Cdd:cd03288   91 HTLR-SRLSIILQ------DPIL-----FSGSIRFNLDPECKCTDDRLWEALEIAQLKnmvkslPGGLdavvTEGGENFS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 156 GGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQrEILQKIY--ALKEEfgfSILFITHDLSLMVEfSDRIGIMYSGELI 233
Cdd:cd03288  159 VGQRQLFCLARAFVRKSSILIMDEATASIDMATE-NILQKVVmtAFADR---TVVTIAHRVSTILD-ADLVLVLSRGILV 233


                 .
gi 694160455 234 E 234
Cdd:cd03288  234 E 234

ABCG_PDR_domain1

cd03233

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...

26-233

2.17e-09

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 56.50 E-value: 2.17e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAFITGgEVIFNGENilnySDERMQAFRwSEMSMVFQSamnaln 105
Cdd:cd03233   24 KDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVSVEG-DIHYNGIP----YKEFAEKYP-GEIIYVSEE------ 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 pvlpmeeqfcdvimrhtnmtreqarkraeglleivDIHPSRLT--------------DYPHQFSGGMRQRLVIAIALALN 171
Cdd:cd03233   92 -----------------------------------DVHFPTLTvretldfalrckgnEFVRGISGGERKRVSIAEALVSR 136

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 172 PKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSL-MVEFSDRIGIMYSGELI 233
Cdd:cd03233  137 ASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDeIYDLFDKVLVLYEGRQI 199

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

9-232

2.65e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 58.58 E-value: 2.65e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455     9 RNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRlHKPPAFITGGEVIFNGENiLNYSDERM--- 85
Cdd:TIGR00956  763 RNLTYEVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAE-RVTTGVITGGDRLVNGRP-LDSSFQRSigy 840

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    86 --QAFRWSEMSMV-----FQSAMNALNPVlPMEEQ--FCDVIMRHTNMTreqarKRAEGLLEIVDIhpsrltdyphQFSG 156
Cdd:TIGR00956  841 vqQQDLHLPTSTVreslrFSAYLRQPKSV-SKSEKmeYVEEVIKLLEME-----SYADAVVGVPGE----------GLNV 904

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   157 GMRQRLVIAIALALNPKMII-MDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLS--LMVEFsDRIGIM------ 227
Cdd:TIGR00956  905 EQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADH-GQAILCTIHQPSaiLFEEF-DRLLLLqkggqt 982


                   ....*.
gi 694160455   228 -YSGEL 232
Cdd:TIGR00956  983 vYFGDL 988

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

34-213

3.77e-09

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 54.69 E-value: 3.77e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    34 PGEVFGLAGESGCGKSTVAFSLMRLHKPPafiTGGEVIFNGENILNYSDERMQAFRwsemsmvfqsamnalnpvlpmeeq 113
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPP---GGGVIYIDGEDILEEVLDQLLLII------------------------ 53

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   114 fcdvimrhtnmtreqarkraeglleivdihpsrLTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREIL 193
Cdd:smart00382  54 ---------------------------------VGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLL 100

                          170       180
                   ....*....|....*....|....*
gi 694160455   194 QKIYA-----LKEEFGFSILFITHD 213
Cdd:smart00382 101 LLEELrllllLKSEKNLTVILTTND 125

ABCD_peroxisomal_ALDP

cd03223

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...

6-212

3.81e-09

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).

Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 54.85 E-value: 3.81e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVdyITAAGDVRaCNNVSFDIAPGEVFGLAGESGCGKStvafSLMR------------LHKPPafitGGEVIFn 73
Cdd:cd03223    1 IELENLSL--ATPDGRVL-LKDLSFEIKPGDRLLITGPSGTGKS----SLFRalaglwpwgsgrIGMPE----GEDLLF- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  74 genilnysdermqafrwsemsmvfqsamnalnpvLPmeeqfcdvimRHTNMTReqarkraeGLLEIVDIHPSRltdypHQ 153
Cdd:cd03223   69 ----------------------------------LP----------QRPYLPL--------GTLREQLIYPWD-----DV 91

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVvvqrEILQKIYALKEEFGFSILFITH 212
Cdd:cd03223   92 LSGGEQQRLAFARLLLHKPKFVFLDEATSALDE----ESEDRLYQLLKELGITVISVGH 146

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

137-231

3.83e-09

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 57.51 E-value: 3.83e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 137 LEIVDIHPSRLTDyphqFSGGMRQRLVIAIALALNPKMIIMDEPTTALDvVVQREILQK-IYALKEEFGFSILFITHDLS 215
Cdd:PRK13409 441 LQLERLLDKNVKD----LSGGELQRVAIAACLSRDADLYLLDEPSAHLD-VEQRLAVAKaIRRIAEEREATALVVDHDIY 515

                         90
                 ....*....|....*.
gi 694160455 216 LMVEFSDRIgIMYSGE 231
Cdd:PRK13409 516 MIDYISDRL-MVFEGE 530

ABCC_CFTR2

cd03289

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...

6-219

3.90e-09

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 56.79 E-value: 3.90e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVraCNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLhkppaFITGGEVIFNGeniLNYSDERM 85
Cdd:cd03289    3 MTVKDLTAKYTEGGNAV--LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL-----LNTEGDIQIDG---VSWNSVPL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  86 QAFRWS-----EMSMVFQSAMNA-LNPVlpmeEQFCDvimrhtnmtrEQARKRAE--GLLEIVDIHPSR----LTDYPHQ 153
Cdd:cd03289   73 QKWRKAfgvipQKVFIFSGTFRKnLDPY----GKWSD----------EEIWKVAEevGLKSVIEQFPGQldfvLVDGGCV 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455 154 FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQrEILQKIyaLKEEF-GFSILFITHDLSLMVE 219
Cdd:cd03289  139 LSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITY-QVIRKT--LKQAFaDCTVILSEHRIEAMLE 202

PTZ00265

multidrug resistance protein (mdr1); Provisional

38-224

4.86e-09

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 57.73 E-value: 4.86e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   38 FGLAGESGCGKSTVAFSlmrlhkppafiTGGEVIFNGENILNYSDERMQAFrwseMSMVFQSamnalnPVLPMEEQFCDV 117
Cdd:PTZ00265 1258 FSLTKEGGSGEDSTVFK-----------NSGKILLDGVDICDYNLKDLRNL----FSIVSQE------PMLFNMSIYENI 1316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  118 IMRHTNMTREQARKRAE--GLLEIVDIHPSR----LTDYPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQRE 191
Cdd:PTZ00265 1317 KFGKEDATREDVKRACKfaAIDEFIESLPNKydtnVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKL 1396

                         170       180       190
                  ....*....|....*....|....*....|...
gi 694160455  192 ILQKIYALKEEFGFSILFITHDLSlMVEFSDRI 224
Cdd:PTZ00265 1397 IEKTIVDIKDKADKTIITIAHRIA-SIKRSDKI 1428

sufC

PRK09580

cysteine desulfurase ATPase component; Reviewed

5-234

5.99e-09

cysteine desulfurase ATPase component; Reviewed

Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 55.95 E-value: 5.99e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVdyitAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMrlHKPPAFITGGEVIFNGENILNYSDER 84
Cdd:PRK09580   1 MLSIKDLHV----SVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLA--GREDYEVTGGTVEFKGKDLLELSPED 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 ------MQAFRWS-EMSMV-----FQSAMNALNPVLPMEE----QFCDVImrhtnmtreqarkraEGLLEIVDIHPSRLT 148
Cdd:PRK09580  75 ragegiFMAFQYPvEIPGVsnqffLQTALNAVRSYRGQEPldrfDFQDLM---------------EEKIALLKMPEDLLT 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 149 DYPHQ-FSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFS-DRIGI 226
Cdd:PRK09580 140 RSVNVgFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDG-KRSFIIVTHYQRILDYIKpDYVHV 218


                 ....*...
gi 694160455 227 MYSGELIE 234
Cdd:PRK09580 219 LYQGRIVK 226

PRK13539

cytochrome c biogenesis protein CcmA; Provisional

27-186

7.31e-09

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 54.88 E-value: 7.31e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlNYSDERMQafrwsemsMVFQSAMNALNP 106
Cdd:PRK13539  20 GLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPP----AAGTIKLDGGDI-DDPDVAEA--------CHYLGHRNAMKP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 107 VLPMEE--QFcdviMRHTNMTREQARKRAeglLEIVDIHPsrLTDYPHQF-SGGMRQRLVIAIALALNPKMIIMDEPTTA 183
Cdd:PRK13539  87 ALTVAEnlEF----WAAFLGGEELDIAAA---LEAVGLAP--LAHLPFGYlSAGQKRRVALARLLVSNRPIWILDEPTAA 157


                 ...
gi 694160455 184 LDV 186
Cdd:PRK13539 158 LDA 160

ABCC_SUR1_N

cd03290

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...

15-230

8.03e-09

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 55.03 E-value: 8.03e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  15 YITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMrlhkppafitgGEV-IFNGENILNYSDERMQAFRWSEM 93
Cdd:cd03290    7 YFSWGSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAIL-----------GEMqTLEGKVHWSNKNESEPSFEATRS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  94 SMVFQSAMNALNPVL---PMEEQFcdVIMRHTNMTREQARKRAEGLLEIVDIHP----SRLTDYPHQFSGGMRQRLVIAI 166
Cdd:cd03290   76 RNRYSVAYAAQKPWLlnaTVEENI--TFGSPFNKQRYKAVTDACSLQPDIDLLPfgdqTEIGERGINLSGGQRQRICVAR 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 167 ALALNPKMIIMDEPTTALDVVVQREILQK-IYALKEEFGFSILFITHDLSLMVEfSDRIGIMYSG 230
Cdd:cd03290  154 ALYQNTNIVFLDDPFSALDIHLSDHLMQEgILKFLQDDKRTLVLVTHKLQYLPH-ADWIIAMKDG 217

PRK10636

putative ABC transporter ATP-binding protein; Provisional

26-224

8.57e-09

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 56.72 E-value: 8.57e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLHKPPAFITGGEVIFNGENILNYSDERMQA---------------FRW 90
Cdd:PRK10636  18 DNATATINPGQKVGLVGKNGCGKST----LLALLKNEISADGGSYTFPGNWQLAWVNQETPAlpqpaleyvidgdreYRQ 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  91 SEMSMVFQSAMNALNPVLPMEEQFcDVIMRHTnmtreqARKRAEGLLEIVDIHPSRLTDYPHQFSGGMRQRLVIAIALAL 170
Cdd:PRK10636  94 LEAQLHDANERNDGHAIATIHGKL-DAIDAWT------IRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALIC 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 171 NPKMIIMDEPTTALDV--VVQREILQKIYAlkeefGFSILfITHDLSLMVEFSDRI 224
Cdd:PRK10636 167 RSDLLLLDEPTNHLDLdaVIWLEKWLKSYQ-----GTLIL-ISHDRDFLDPIVDKI 216

ABC_CcmA_heme_exporter

cd03231

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...

11-216

1.27e-08

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.

Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 54.04 E-value: 1.27e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  11 LCVDYITAAGDVRAC-NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfitgGEVIFNGENILNYSDERMQAFR 89
Cdd:cd03231    1 LEADELTCERDGRALfSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLA----GRVLLNGGPLDFQRDSIARGLL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  90 WsemsMVFQSAMNALNPVLPMEEQFCDVimrHTNMTREQARKRAeGLleivdihpSRLTDYP-HQFSGGMRQRLVIAIAL 168
Cdd:cd03231   77 Y----LGHAPGIKTTLSVLENLRFWHAD---HSDEQVEEALARV-GL--------NGFEDRPvAQLSAGQQRRVALARLL 140

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 694160455 169 ALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSL 216
Cdd:cd03231  141 LSGRPLWILDEPTTALDKAGVARFAEAMAGHCARGGMVVLTTHQDLGL 188

ABCG_PDR_domain2

cd03232

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...

6-185

1.79e-08

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 53.40 E-value: 1.79e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRL--HKPPAFITGGEVIFNGenilnysde 83
Cdd:cd03232    4 LTWKNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTT----LLDVlaGRKTAGVITGEILING--------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  84 rmqafrwsemsmvfqsamnalnpvLPMEEQFcdvimrhtnmtreqarKRAEGLLEIVDIHPSRLTDY-PHQFSGGMR--- 159
Cdd:cd03232   71 ------------------------RPLDKNF----------------QRSTGYVEQQDVHSPNLTVReALRFSALLRgls 110

                        170       180       190
                 ....*....|....*....|....*....|
gi 694160455 160 ----QRLVIAIALALNPKMIIMDEPTTALD 185
Cdd:cd03232  111 veqrKRLTIGVELAAKPSILFLDEPTSGLD 140

PLN03211

ABC transporter G-25; Provisional

26-199

2.95e-08

ABC transporter G-25; Provisional

Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 54.89 E-value: 2.95e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLM-RLHkppAFITGGEVIFNGENILNYSDERMQafrwsemsmvFQSAMNAL 104
Cdd:PLN03211  85 NGVTGMASPGEILAVLGPSGSGKSTLLNALAgRIQ---GNNFTGTILANNRKPTKQILKRTG----------FVTQDDIL 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 105 NPVLPMEEQ--FCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQF----SGGMRQRLVIAIALALNPKMIIMD 178
Cdd:PLN03211 152 YPHLTVRETlvFCSLLRLPKSLTKQEKILVAESVISELGLTKCENTIIGNSFirgiSGGERKRVSIAHEMLINPSLLILD 231

                        170       180
                 ....*....|....*....|.
gi 694160455 179 EPTTALDVVVQREILQKIYAL 199
Cdd:PLN03211 232 EPTSGLDATAAYRLVLTLGSL 252

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

155-231

4.00e-08

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 54.41 E-value: 4.00e-08

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDvVVQREILQK-IYALKEEFGFSILFITHDLSLMVEFSDRIgIMYSGE 231
Cdd:COG1245  457 SGGELQRVAIAACLSRDADLYLLDEPSAHLD-VEQRLAVAKaIRRFAENRGKTAMVVDHDIYLIDYISDRL-MVFEGE 532

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

6-219

7.37e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 54.15 E-value: 7.37e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455     6 ISIRNLCVDYITAAGDVraCNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKppafiTGGEVIFNGeniLNYSDERM 85
Cdd:TIGR01271 1218 MDVQGLTAKYTEAGRAV--LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-----TEGEIQIDG---VSWNSVTL 1287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    86 QAFRWS-----EMSMVFQSA--MNaLNPvlpmEEQFCDvimrhtnmtrEQARKRAE--GLLEIVDIHPSR----LTDYPH 152
Cdd:TIGR01271 1288 QTWRKAfgvipQKVFIFSGTfrKN-LDP----YEQWSD----------EEIWKVAEevGLKSVIEQFPDKldfvLVDGGY 1352

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 694160455   153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQrEILQKiyALKEEFG-FSILFITHDLSLMVE 219
Cdd:TIGR01271 1353 VLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTL-QIIRK--TLKQSFSnCTVILSEHRVEALLE 1417

PRK13538

cytochrome c biogenesis heme-transporting ATPase CcmA;

27-186

9.07e-08

cytochrome c biogenesis heme-transporting ATPase CcmA;

Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 51.73 E-value: 9.07e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  27 NVSFDIAPGEVFGLAGESGCGKStvafSLMRLhkppafITG------GEVIFNGENILNYSDERMQafrwsemSMVFQSA 100
Cdd:PRK13538  19 GLSFTLNAGELVQIEGPNGAGKT----SLLRI------LAGlarpdaGEVLWQGEPIRRQRDEYHQ-------DLLYLGH 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 101 MNALNPVLPMEE--QFcdvIMRHTNMTREQARKRAeglLEIVDIhpSRLTDYP-HQFSGGMRQRlvIAIA-LAL-NPKMI 175
Cdd:PRK13538  82 QPGIKTELTALEnlRF---YQRLHGPGDDEALWEA---LAQVGL--AGFEDVPvRQLSAGQQRR--VALArLWLtRAPLW 151

                        170
                 ....*....|.
gi 694160455 176 IMDEPTTALDV 186
Cdd:PRK13538 152 ILDEPFTAIDK 162

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

34-231

1.28e-07

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 52.89 E-value: 1.28e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  34 PGEVFGLAGESGCGKSTVafslMRlhkppafITGGEVIFN-GENILNYS-DERMQAFRWSEMSMVFQS-AMNALNPVL-P 109
Cdd:PRK13409  98 EGKVTGILGPNGIGKTTA----VK-------ILSGELIPNlGDYEEEPSwDEVLKRFRGTELQNYFKKlYNGEIKVVHkP 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 110 meeQFCDVIMRHTN------MTREQARKRAEGLLEIVDIHPsrLTDYP-HQFSGGMRQRLVIAIALALNPKMIIMDEPTT 182
Cdd:PRK13409 167 ---QYVDLIPKVFKgkvrelLKKVDERGKLDEVVERLGLEN--ILDRDiSELSGGELQRVAIAAALLRDADFYFFDEPTS 241

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 694160455 183 ALDvVVQR-EILQKIYALKEefGFSILFITHDLSLMVEFSDRIGIMYsGE 231
Cdd:PRK13409 242 YLD-IRQRlNVARLIRELAE--GKYVLVVEHDLAVLDYLADNVHIAY-GE 287

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

26-240

1.57e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 52.42 E-value: 1.57e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSL--MRLHKppafitGGEVIFNGENILNYS-------------DERMQAFRW 90
Cdd:PRK10982 265 RDVSFDLHKGEILGIAGLVGAKRTDIVETLfgIREKS------AGTITLHGKKINNHNaneainhgfalvtEERRSTGIY 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  91 SEMSMVFQSAMNALNpvlpmeeqfcdvimRHTNMTREQARKRAEGLLEIVdIHPSRLTDYPHQ-----FSGGMRQRLVIA 165
Cdd:PRK10982 339 AYLDIGFNSLISNIR--------------NYKNKVGLLDNSRMKSDTQWV-IDSMRVKTPGHRtqigsLSGGNQQKVIIG 403

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 166 IALALNPKMIIMDEPTTALDVVVQREILQKIYAL-KEEFGfsILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQ 240
Cdd:PRK10982 404 RWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELaKKDKG--IIIISSEMPELLGITDRILVMSNGLVAGIVDTKT 477

ABC_Class2

cd03227

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...

152-228

1.64e-07

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.

Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 50.05 E-value: 1.64e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 152 HQFSGGMRQRLVIAIALALNPK----MIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLsLMVEFSDRIGIM 227
Cdd:cd03227   76 LQLSGGEKELSALALILALASLkprpLYILDEIDRGLDPRDGQALAEAILEHLVK-GAQVIVITHLP-ELAELADKLIHI 153


                 .
gi 694160455 228 Y 228
Cdd:cd03227  154 K 154

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

34-231

1.64e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 52.48 E-value: 1.64e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  34 PGEVFGLAGESGCGKSTVafslMRlhkppafITGGEVIFN---GENILNYsDERMQAFRWSEMSMVFQSAMN-----ALN 105
Cdd:COG1245   98 KGKVTGILGPNGIGKSTA----LK-------ILSGELKPNlgdYDEEPSW-DEVLKRFRGTELQDYFKKLANgeikvAHK 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 106 PvlpmeeQFCDVI-MRHTNMTRE-----QARKRAEGLLEIVDIHPSRLTDYpHQFSGGMRQRLVIAIALALNPKMIIMDE 179
Cdd:COG1245  166 P------QYVDLIpKVFKGTVREllekvDERGKLDELAEKLGLENILDRDI-SELSGGELQRVAIAAALLRDADFYFFDE 238

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 694160455 180 PTTALDvVVQR----EILQKiyaLKEEfGFSILFITHDLSLMVEFSDRIGIMYsGE 231
Cdd:COG1245  239 PSSYLD-IYQRlnvaRLIRE---LAEE-GKYVLVVEHDLAILDYLADYVHILY-GE 288

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

3-212

2.08e-07

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 52.32 E-value: 2.08e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   3 APLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVaFSLmrlhkppafITGGE--------VIF-- 72
Cdd:PRK10938 258 EPRIVLNNGVVSY----NDRPILHNLSWQVNPGEHWQIVGPNGAGKSTL-LSL---------ITGDHpqgysndlTLFgr 323

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  73 ---NGENIlnYSDERMQAFRWSEMSMVFQSAMNALNPVLpmeEQFCDVIMRHTNMTREQaRKRAEGLLEIVDIhPSRLTD 149
Cdd:PRK10938 324 rrgSGETI--WDIKKHIGYVSSSLHLDYRVSTSVRNVIL---SGFFDSIGIYQAVSDRQ-QKLAQQWLDILGI-DKRTAD 396

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455 150 YP-HQFSGGmRQRLV-IAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITH 212
Cdd:PRK10938 397 APfHSLSWG-QQRLAlIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSH 460

MK0520

COG2401

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...

26-212

2.10e-07

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];

Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 50.73 E-value: 2.10e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPPAfiTGGEVIFNGENIlnysdermqafrWSEMSMV--------F 97
Cdd:COG2401   47 RDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTP--VAGCVDVPDNQF------------GREASLIdaigrkgdF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  98 QSAMNALNPVlpmeeqfcdvimrhtnmtreqarkraeGLLEIVdihpSRLTDYPHqFSGGMRQRLVIAIALALNPKMIIM 177
Cdd:COG2401  113 KDAVELLNAV---------------------------GLSDAV----LWLRRFKE-LSTGQKFRFRLALLLAERPKLLVI 160

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 694160455 178 DEPTTALDVVVQREILQKIYALKEEFGFSILFITH 212
Cdd:COG2401  161 DEFCSHLDRQTAKRVARNLQKLARRAGITLVVATH 195

PRK10636

putative ABC transporter ATP-binding protein; Provisional

4-232

9.74e-07

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 50.17 E-value: 9.74e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   4 PLISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLHKPPAFITGGEV-IFNGENILNYSD 82
Cdd:PRK10636 311 PLLKMEKVSAGY----GDRIILDSIKLNLVPGSRIGLLGRNGAGKST----LIKLLAGELAPVSGEIgLAKGIKLGYFAQ 382

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  83 ERMQAFRWSEmsmvfqSAMNALNPVLPMEeqfcdvimrhtnmTREQARKRAEGLleivDIHPSRLTDYPHQFSGGMRQRL 162
Cdd:PRK10636 383 HQLEFLRADE------SPLQHLARLAPQE-------------LEQKLRDYLGGF----GFQGDKVTEETRRFSGGEKARL 439

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 163 VIAIALALNPKMIIMDEPTTALDVVVQReilqkiyALKE---EFGFSILFITHDLSLMVEFSDRIGIMYSGEL 232
Cdd:PRK10636 440 VLALIVWQRPNLLLLDEPTNHLDLDMRQ-------ALTEaliDFEGALVVVSHDRHLLRSTTDDLYLVHDGKV 505

3a01203

TIGR00954

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...

13-216

2.28e-06

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 48.98 E-value: 2.28e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   13 VDYITAAGDVrACNNVSFDIAPGEVFGLAGESGCGKStvafSLMRLHKPPAFITGGEVIFNGENILNYSDERMQAFRWSE 92
Cdd:TIGR00954 457 IPLVTPNGDV-LIESLSFEVPSGNNLLICGPNGCGKS----SLFRILGELWPVYGGRLTKPAKGKLFYVPQRPYMTLGTL 531

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   93 MSMVfqsamnalnpVLPME-EQFCDvimrhtnmtREQARKRAEGLLEIVDIHP--------SRLTDYPHQFSGGMRQRLV 163
Cdd:TIGR00954 532 RDQI----------IYPDSsEDMKR---------RGLSDKDLEQILDNVQLTHilereggwSAVQDWMDVLSGGEKQRIA 592

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 694160455  164 IAIALALNPKMIIMDEPTTALDVVVQreilQKIYALKEEFGFSILFITHDLSL 216
Cdd:TIGR00954 593 MARLFYHKPQFAILDECTSAVSVDVE----GYMYRLCREFGITLFSVSHRKSL 641

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

6-243

2.75e-06

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 49.17 E-value: 2.75e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455     6 ISIRNlcVDYITAAGDVRACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLM-RLHKppafiTGGEVIFNGEniLNYSDEr 84
Cdd:TIGR00957  637 ITVHN--ATFTWARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLaEMDK-----VEGHVHMKGS--VAYVPQ- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    85 mQAfrWSEMSMVFQSAM--NALNPvlpmeeqfcdvimrhtnmTREQARKRAEGLLEIVDIHPS----RLTDYPHQFSGGM 158
Cdd:TIGR00957  707 -QA--WIQNDSLRENILfgKALNE------------------KYYQQVLEACALLPDLEILPSgdrtEIGEKGVNLSGGQ 765

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   159 RQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEF-GFSILFITHDLSLMVEfSDRIGIMYSGELIEVAP 237
Cdd:TIGR00957  766 KQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFEHVIGPEGVLkNKTRILVTHGISYLPQ-VDVIIVMSGGKISEMGS 844


                   ....*.
gi 694160455   238 SKQILE 243
Cdd:TIGR00957  845 YQELLQ 850

ABC_RNaseL_inhibitor

cd03222

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...

155-228

5.94e-06

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 46.03 E-value: 5.94e-06

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMY 228
Cdd:cd03222   73 SGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVFE 146

PLN03073

ABC transporter F family; Provisional

26-186

1.04e-05

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 47.16 E-value: 1.04e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  26 NNVSFDIAPGEVFGLAGESGCGKSTVaFSLMRLHKppafITG---------------GEVIFNGENILNYSDERMQAF-- 88
Cdd:PLN03073 194 VDASVTLAFGRHYGLVGRNGTGKTTF-LRYMAMHA----IDGipkncqilhveqevvGDDTTALQCVLNTDIERTQLLee 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  89 --------RWSEMSMVFQSAMNALNPVL---PMEEQFCDVIMRHTNMTREQARKRAEGLLEIVDIHPSRLTDYPHQFSGG 157
Cdd:PLN03073 269 eaqlvaqqRELEFETETGKGKGANKDGVdkdAVSQRLEEIYKRLELIDAYTAEARAASILAGLSFTPEMQVKATKTFSGG 348

                        170       180
                 ....*....|....*....|....*....
gi 694160455 158 MRQRLVIAIALALNPKMIIMDEPTTALDV 186
Cdd:PLN03073 349 WRMRIALARALFIEPDLLLLDEPTNHLDL 377

ABCC_MRP_domain1

cd03250

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...

6-231

1.05e-05

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 45.54 E-value: 1.05e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVRAC-NNVSFDIAPGEVFGLAGESGCGKSTVAFSLM-RLHKPPAFIT-GGEV--------IFNG 74
Cdd:cd03250    1 ISVEDASFTWDSGEQETSFTlKDINLEVPKGELVAIVGPVGSGKSSLLSALLgELEKLSGSVSvPGSIayvsqepwIQNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  75 ---ENIL---NYSDERmqafrwsemsmvFQSAMNA--LNPVLpmeEQFCDVIM-----RHTNMtreqarkraeglleivd 141
Cdd:cd03250   81 tirENILfgkPFDEER------------YEKVIKAcaLEPDL---EILPDGDLteigeKGINL----------------- 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 142 ihpsrltdyphqfSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIY--ALKEefGFSILFITHDLSLMVE 219
Cdd:cd03250  129 -------------SGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRHIFENCIlgLLLN--NKTRILVTHQLQLLPH 193

                        250
                 ....*....|..
gi 694160455 220 FsDRIGIMYSGE 231
Cdd:cd03250  194 A-DQIVVLDNGR 204

PRK11147

ABC transporter ATPase component; Reviewed

5-224

1.66e-05

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 46.48 E-value: 1.66e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   5 LISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLM-----------------------RLHK- 60
Cdd:PRK11147   3 LISIHGAWLSF----SDAPLLDNAELHIEDNERVCLVGRNGAGKST----LMkilngevllddgriiyeqdlivaRLQQd 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  61 PPAFITGGEVIFNGENILNYSDERMQAFRWSEMSMVFQSAMNaLNPVLPMEEQfcdviMRHTNMTreQARKRAEGLLEIV 140
Cdd:PRK11147  75 PPRNVEGTVYDFVAEGIEEQAEYLKRYHDISHLVETDPSEKN-LNELAKLQEQ-----LDHHNLW--QLENRINEVLAQL 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 141 DIHP-SRLTDyphqFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVvvqrEILQKIYALKEEFGFSILFITHDLSLMVE 219
Cdd:PRK11147 147 GLDPdAALSS----LSGGWLRKAALGRALVSNPDVLLLDEPTNHLDI----ETIEWLEGFLKTFQGSIIFISHDRSFIRN 218


                 ....*
gi 694160455 220 FSDRI 224
Cdd:PRK11147 219 MATRI 223

ABC_UvrA

cd03238

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...

22-235

1.69e-05

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 44.62 E-value: 1.69e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  22 VRACNNVSFDIAPGEVFGLAGESGCGKSTVAFslmrlhkppafitggEVIF-NGENILNYSDERmqafrWSEMSMVFQSA 100
Cdd:cd03238    8 VHNLQNLDVSIPLNVLVVVTGVSGSGKSTLVN---------------EGLYaSGKARLISFLPK-----FSRNKLIFIDQ 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 101 MNALnpvlpmeeqfcdVIMRHTNMTREQARkraeglleivdihpSRLtdyphqfSGGMRQRLVIAIALALNPK--MIIMD 178
Cdd:cd03238   68 LQFL------------IDVGLGYLTLGQKL--------------STL-------SGGELQRVKLASELFSEPPgtLFILD 114

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 694160455 179 EPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMvEFSDRIGIM------YSGELIEV 235
Cdd:cd03238  115 EPSTGLHQQDINQLLEVIKGLIDL-GNTVILIEHNLDVL-SSADWIIDFgpgsgkSGGKVVFS 175

GguA

NF040905

sugar ABC transporter ATP-binding protein;

155-236

6.26e-05

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 44.40 E-value: 6.26e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEfGFSILFITHDLSLMVEFSDRIGIMYSGELI- 233
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLGMCDRIYVMNEGRITg 484


                 ...
gi 694160455 234 EVA 236
Cdd:NF040905 485 ELP 487

COG1106

ATPase/GTPase, AAA15 family [General function prediction only];

42-222

6.74e-05

ATPase/GTPase, AAA15 family [General function prediction only];

Pssm-ID: 440723 [Multi-domain] Cd Length: 330 Bit Score: 43.88 E-value: 6.74e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  42 GESGCGKSTV--AFSLMR------------LHKPPAFITGG-------EVIFNGENI-----LNYSDER----------- 84
Cdd:COG1106   36 GANASGKSNLleALYFLRnlvlnssqpgdkLVEPFLLDSESknepsefEILFLLDGVryeygFELDKERiisewlyflst 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  85 ---------MQAFRWSEMSMVFQSAMNALNPVLPMEEQFCDVIMRH-----TNMTR---EQARKRAEGLLEIVDIHPSRL 147
Cdd:COG1106  116 aaqlnvpllSPLYDWFDNNISLDTSSDGLTLLLKEDESLKEELLELlkiadPGIEDievEEEEIEDLVERKLIFKHKGGN 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 694160455 148 TDYP-HQFSGGMRQ--RLVIAIALAL-NPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSD 222
Cdd:COG1106  196 VPLPlSEESDGTKRllALAGALLDALaKGGVLLIDEIEASLHPSLLRKLLKLFLDLANKNNAQLIFTTHSTELLDAFLE 274

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

6-185

1.02e-04

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 43.96 E-value: 1.02e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYitaaGDVRACNNVSFDIAPGEVFGLAGESGCGKSTvafsLMRLhkppafITG------GEVIFNGENILN 79
Cdd:NF033858   2 ARLEGVSHRY----GKTVALDDVSLDIPAGCMVGLIGPDGVGKSS----LLSL------IAGarkiqqGRVEVLGGDMAD 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  80 YSDERMQAFRWSEMSmvfQSAMNALNPVLPMEE--QFcdvIMRHTNMTREQARKRAEGLLEIVDIHPSRltDYPH-QFSG 156
Cdd:NF033858  68 ARHRRAVCPRIAYMP---QGLGKNLYPTLSVFEnlDF---FGRLFGQDAAERRRRIDELLRATGLAPFA--DRPAgKLSG 139

                        170       180
                 ....*....|....*....|....*....
gi 694160455 157 GMRQRLVIAIALALNPKMIIMDEPTTALD 185
Cdd:NF033858 140 GMKQKLGLCCALIHDPDLLILDEPTTGVD 168

PvdE

COG4615

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...

6-97

1.24e-04

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];

Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 43.63 E-value: 1.24e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   6 ISIRNLCVDYITAAGDVR-ACNNVSFDIAPGEVFGLAGESGCGKSTVAFSLMRLHKPpafiTGGEVIFNGENIlnySDER 84
Cdd:COG4615  328 LELRGVTYRYPGEDGDEGfTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRP----ESGEILLDGQPV---TADN 400

                         90
                 ....*....|...
gi 694160455  85 MQAFRwSEMSMVF 97
Cdd:COG4615  401 REAYR-QLFSAVF 412

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

153-224

1.61e-04

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 43.39 E-value: 1.61e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 694160455  153 QFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVvvqrEILQkiyALKE---EFGFSILFITHDLSlmveFSDRI 224
Cdd:TIGR03719 443 QLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDV----ETLR---ALEEallNFAGCAVVISHDRW----FLDRI 506

PLN03140

ABC transporter G family member; Provisional

159-185

1.75e-04

ABC transporter G family member; Provisional

Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 43.30 E-value: 1.75e-04

                          10        20
                  ....*....|....*....|....*..
gi 694160455  159 RQRLVIAIALALNPKMIIMDEPTTALD 185
Cdd:PLN03140 1025 RKRLTIAVELVANPSIIFMDEPTSGLD 1051

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

32-243

2.67e-04

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 42.79 E-value: 2.67e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455    32 IAPGEVFGLAGESGCGKST----VAFSLMRLHKPpafiTGGEVIFNGenilnYSDERMQAFRWSEmsmVFQSAMNALN-P 106
Cdd:TIGR00956   84 IKPGELTVVLGRPGSGCSTllktIASNTDGFHIG----VEGVITYDG-----ITPEEIKKHYRGD---VVYNAETDVHfP 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455   107 VLPMEEQFCDVIM------RHTNMTREQ-ARKRAEGLLEIVDIHPSRLT----DYPHQFSGGMRQRLVIAIALALNPKMI 175
Cdd:TIGR00956  152 HLTVGETLDFAARcktpqnRPDGVSREEyAKHIADVYMATYGLSHTRNTkvgnDFVRGVSGGERKRVSIAEASLGGAKIQ 231

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 694160455   176 IMDEPTTALDVVVQREIlqkIYALKEefgfsILFITHDLSLMV---------EFSDRIGIMYSGELIEVAPSKQILE 243
Cdd:TIGR00956  232 CWDNATRGLDSATALEF---IRALKT-----SANILDTTPLVAiyqcsqdayELFDKVIVLYEGYQIYFGPADKAKQ 300

ABC_Rad50

cd03240

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...

147-213

2.78e-04

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.

Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 41.44 E-value: 2.78e-04

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 694160455 147 LTDYPHQFSGGMRQRLVIAIALAL------NPKMIIMDEPTTALDVVVQREILQKIY-ALKEEFGFSILFITHD 213
Cdd:cd03240  109 LLDMRGRCSGGEKVLASLIIRLALaetfgsNCGILALDEPTTNLDEENIEESLAEIIeERKSQKNFQLIVITHD 182

PLN03130

ABC transporter C family member; Provisional

155-234

3.49e-04

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 42.42 E-value: 3.49e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKiyALKEEF-GFSILFITHDLSLMVEFsDRIGIMYSGELI 233
Cdd:PLN03130  742 SGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFDK--CIKDELrGKTRVLVTNQLHFLSQV-DRIILVHEGMIK 818


                  .
gi 694160455  234 E 234
Cdd:PLN03130  819 E 819

PRK11147

ABC transporter ATPase component; Reviewed

155-213

1.07e-03

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 40.70 E-value: 1.07e-03

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455 155 SGGMRQRLVIAiALALNP-KMIIMDEPTTALDVvvqrEILQKIYALKEEFGFSILFITHD 213
Cdd:PRK11147 442 SGGERNRLLLA-RLFLKPsNLLILDEPTNDLDV----ETLELLEELLDSYQGTVLLVSHD 496

PLN03232

ABC transporter C family member; Provisional

155-234

6.65e-03

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 38.42 E-value: 6.65e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 694160455  155 SGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKiyALKEEF-GFSILFITHDLSLMVEFsDRIGIMYSGELI 233
Cdd:PLN03232  742 SGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDS--CMKDELkGKTRVLVTNQLHFLPLM-DRIILVSEGMIK 818


                  .
gi 694160455  234 E 234
Cdd:PLN03232  819 E 819

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01