|
Name |
Accession |
Description |
Interval |
E-value |
| cyclopro_CfaB |
NF040703 |
C17 cyclopropane fatty acid synthase CfaB; |
14-423 |
9.51e-101 |
|
C17 cyclopropane fatty acid synthase CfaB;
Pssm-ID: 468667 [Multi-domain] Cd Length: 393 Bit Score: 305.38 E-value: 9.51e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 14 LAALVSPLAGGALPVRLRAWDGSES--GPAGGPVLVIRDRKALRRLMW-SPDELGlaQAYIAGEIDVEGDLGAGLRqvwq 90
Cdd:NF040703 2 LAQLPPALRNLQLPLRLRLWDGKQLdlGPSPRVTLVVKDPSLLSQLTHpSLDLLG--SAYVEGRLDLEGPIMEVIR---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 91 qararglarggvrvgLGDKLRAvrtllrlGVLGPKPPAPDVQarivgDLHSRERDRAAISYHYDLSNEFYALILDERMAY 170
Cdd:NF040703 76 ---------------VGDELSQ-------ALLGDDDEAPPER-----TAHDKATDAAAISYHYDLSNDFYALWLDPDMVY 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 171 SCGYWTSdaPGYGLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARVG--G 248
Cdd:NF040703 129 SCAYFET--GTEDLAQAQQAKLRHLCRKLRLQPGERLLDVGCGWGGLARFAAREFGVEVFGITLSKEQLKLARERVAaeG 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 249 LP--VDFRLQDYRDV-ADGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRPEGrlLVqqMSRGATAP---------GGGA 316
Cdd:NF040703 207 LQdrVQLELLDYRDLpQDGRFDKVVSVGMFEHVGHANLPLYCQRLFGAVRPGG--LV--MNHGITARhtdgrpvgrGAGE 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 317 FIESYVAPDMHMRPVGQTVDLLEQAGLEVRDVHALREHYVRTVGVWLETLEARWDAVVALVGEPMARVWRLYLVGGALTF 396
Cdd:NF040703 283 FIGRYVFPHGELPHLATITASISEAGLEVVDVESLRLHYARTLEHWSARLEARLDEAARLVPERALRIWRLYLAGCAYGF 362
|
410 420
....*....|....*....|....*..
gi 556037765 397 EEGRMGVDQILAVRPTETGVSGMPATR 423
Cdd:NF040703 363 ARGWINLHQILAVKPLADGSHELPWTR 389
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
141-406 |
1.33e-91 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 277.67 E-value: 1.33e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 141 SRERDRAAISYHYDLSNEFYALILDERMAYSCGYWTSdaPGYGLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLH 220
Cdd:pfam02353 1 SKTRDAENIQAHYDLSNDFFALFLDPTMTYSCAYFER--PDMTLEEAQQAKLDLILDKLGLKPGMTLLDIGCGWGGLMRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 221 AAKNYGVTVTGVTLSREQLAFAQARVG--GLP--VDFRLQDYRDVaDGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRP 296
Cdd:pfam02353 79 AAERYDVNVVGLTLSKNQYKLARKRVAaeGLArkVEVLLQDYRDF-DEPFDRIVSVGMFEHVGHENYDTFFKKLYNLLPP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 297 EGRLLVQQMS---RGATAPGGGA--FIESYVAPDMHMRPVGQTVDLLEQAGLEVRDVHALREHYVRTVGVWLETLEARWD 371
Cdd:pfam02353 158 GGLMLLHTITglhPDETSERGLPlkFIDKYIFPGGELPSISMIVESSSEAGFTVEDVESLRPHYAKTLDLWAENLQANKD 237
|
250 260 270
....*....|....*....|....*....|....*
gi 556037765 372 AVVALVGEPMARVWRLYLVGGALTFEEGRMGVDQI 406
Cdd:pfam02353 238 EAIALQSEEFYRMWMLYLTGCAVAFRIGYIDVHQF 272
|
|
| PRK11705 |
PRK11705 |
cyclopropane fatty acyl phospholipid synthase; |
103-396 |
4.62e-77 |
|
cyclopropane fatty acyl phospholipid synthase;
Pssm-ID: 183282 Cd Length: 383 Bit Score: 243.99 E-value: 4.62e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 103 RVGLGDKLRA-VRTLLRLgvlgpkppapdVQARIVgDLHSRERDRAAISYHYDLSNEFYALILDERMAYSCGYW--TSDa 179
Cdd:PRK11705 81 RAGLDEKLPHhLKDTLRI-----------LRARLF-NLQSKKRAWIVGKEHYDLGNDLFEAMLDPRMQYSCGYWkdADT- 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 180 pgygLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARVGGLPVDFRLQDYR 259
Cdd:PRK11705 148 ----LEEAQEAKLDLICRKLQLKPGMRVLDIGCGWGGLARYAAEHYGVSVVGVTISAEQQKLAQERCAGLPVEIRLQDYR 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 260 DVaDGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRPEGRLLVQQMSRGATAPGGGAFIESYVAPDMHMRPVGQTVDLLE 339
Cdd:PRK11705 224 DL-NGQFDRIVSVGMFEHVGPKNYRTYFEVVRRCLKPDGLFLLHTIGSNKTDTNVDPWINKYIFPNGCLPSVRQIAQASE 302
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 556037765 340 qaGLEV-RDVHALREHYVRTVGVWLETLEARWDAVVALVGEPMARVWRLYLVGGALTF 396
Cdd:PRK11705 303 --GLFVmEDWHNFGADYDRTLMAWHENFEAAWPELADNYSERFYRMWRYYLLSCAGAF 358
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
151-303 |
1.52e-68 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 214.41 E-value: 1.52e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 151 YHYDLSNEFYALILDERMAYSCGYWTSdaPGYGLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVT 230
Cdd:COG2230 1 HHYDLGNDFYRLFLDPTMTYSCAYFED--PDDTLEEAQEAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVT 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556037765 231 GVTLSREQLAFAQARV--GGLP--VDFRLQDYRDV-ADGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRPEGRLLVQ 303
Cdd:COG2230 79 GVTLSPEQLEYARERAaeAGLAdrVEVRLADYRDLpADGQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLH 156
|
|
| mycolic_MTase |
NF040660 |
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include ... |
125-405 |
2.50e-52 |
|
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include tailoring enzymes that make site-specific modifications to mycolic acid precursor molecules. These include Mycobacterium tuberculosis enzymes MmaA1-MmaA4, CmaA1-CmaA2, and PcaA. The family also includes UmaA, reported to be the lone member of this family not involved in mycolic acid biosynthesis. No members of this family are found in species that lack mycolic acids. This model excludes two more distantly related paralogs, Rv0447c (UfaA1 ) and Rv3720, that are also encoded in the Mycobacterium tuberculosis H37Rv genome.
Pssm-ID: 468626 Cd Length: 283 Bit Score: 176.88 E-value: 2.50e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 125 KPPAPDVQArivgdlhsrerdraaisyHYDLSNEFYALILDERMAYSCGYWtsDAPGYGLAEAQTDKLDLVCRKLGLEPG 204
Cdd:NF040660 2 RPHFEDVQA------------------HYDLSDDFFALFLDPTQTYSCAYF--ERDDMTLEEAQIAKIDLALGKLNLEPG 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 205 MRLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARVGGLPV----DFRLQDYRDVADgPYDAISTIEMGEHVGQ 280
Cdd:NF040660 62 MTLLDIGCGWGATMRRAVEKYDVNVVGLTLSKNQAAHVQQVLDEIDTprsrRVLLQGWEEFDE-PVDRIVSIGAFEHFGH 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 281 GQYPVFAAQLHRLLRPEGRLLVQQMS---------RGATAPGGGA----FIESYVAPDMHMRPVGQTVDLLEQAGLEVRD 347
Cdd:NF040660 141 ERYDDFFKRAYNILPADGRMLLHTITglhrkemheRGLPLTMELArfikFIVTEIFPGGRLPSIEMVVEHAEKAGFTVTR 220
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 556037765 348 VHALREHYVRTVGVWLETLEARWDAVVALVGEPMARVWRLYLVGGALTFEEGRMGVDQ 405
Cdd:NF040660 221 VQSLQPHYARTLDLWADALQAHKDEAIAIQSEEVYERYMKYLTGCAKLFRDGYIDVNQ 278
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
206-303 |
3.51e-12 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 62.45 E-value: 3.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 206 RLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQ---ARVGGLPVDFRLQDYRDV---ADGPYDAISTIEMGEHVG 279
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARkaaAALLADNVEVLKGDAEELppeADESFDVIISDPPLHHLV 80
|
90 100
....*....|....*....|....
gi 556037765 280 QGQYPVFaAQLHRLLRPEGRLLVQ 303
Cdd:cd02440 81 EDLARFL-EEARRLLKPGGVLVLT 103
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
206-311 |
2.06e-07 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 51.65 E-value: 2.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 206 RLLDVGCGWGALGLHAAKNYG-VTVTGVTLSREQLAFAQARVGGLPVDFRLQ-DYRDVADGP----YDAISTIEMGEHVg 279
Cdd:smart00828 2 RVLDFGCGYGSDLIDLAERHPhLQLHGYTISPEQAEVGRERIRALGLQGRIRiFYRDSAKDPfpdtYDLVFGFEVIHHI- 80
|
90 100 110
....*....|....*....|....*....|...
gi 556037765 280 QGQYPVFAAqLHRLLRPEGRLLVQQ-MSRGATA 311
Cdd:smart00828 81 KDKMDLFSN-ISRHLKDGGHLVLADfIANLLSA 112
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| cyclopro_CfaB |
NF040703 |
C17 cyclopropane fatty acid synthase CfaB; |
14-423 |
9.51e-101 |
|
C17 cyclopropane fatty acid synthase CfaB;
Pssm-ID: 468667 [Multi-domain] Cd Length: 393 Bit Score: 305.38 E-value: 9.51e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 14 LAALVSPLAGGALPVRLRAWDGSES--GPAGGPVLVIRDRKALRRLMW-SPDELGlaQAYIAGEIDVEGDLGAGLRqvwq 90
Cdd:NF040703 2 LAQLPPALRNLQLPLRLRLWDGKQLdlGPSPRVTLVVKDPSLLSQLTHpSLDLLG--SAYVEGRLDLEGPIMEVIR---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 91 qararglarggvrvgLGDKLRAvrtllrlGVLGPKPPAPDVQarivgDLHSRERDRAAISYHYDLSNEFYALILDERMAY 170
Cdd:NF040703 76 ---------------VGDELSQ-------ALLGDDDEAPPER-----TAHDKATDAAAISYHYDLSNDFYALWLDPDMVY 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 171 SCGYWTSdaPGYGLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARVG--G 248
Cdd:NF040703 129 SCAYFET--GTEDLAQAQQAKLRHLCRKLRLQPGERLLDVGCGWGGLARFAAREFGVEVFGITLSKEQLKLARERVAaeG 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 249 LP--VDFRLQDYRDV-ADGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRPEGrlLVqqMSRGATAP---------GGGA 316
Cdd:NF040703 207 LQdrVQLELLDYRDLpQDGRFDKVVSVGMFEHVGHANLPLYCQRLFGAVRPGG--LV--MNHGITARhtdgrpvgrGAGE 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 317 FIESYVAPDMHMRPVGQTVDLLEQAGLEVRDVHALREHYVRTVGVWLETLEARWDAVVALVGEPMARVWRLYLVGGALTF 396
Cdd:NF040703 283 FIGRYVFPHGELPHLATITASISEAGLEVVDVESLRLHYARTLEHWSARLEARLDEAARLVPERALRIWRLYLAGCAYGF 362
|
410 420
....*....|....*....|....*..
gi 556037765 397 EEGRMGVDQILAVRPTETGVSGMPATR 423
Cdd:NF040703 363 ARGWINLHQILAVKPLADGSHELPWTR 389
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
141-406 |
1.33e-91 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 277.67 E-value: 1.33e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 141 SRERDRAAISYHYDLSNEFYALILDERMAYSCGYWTSdaPGYGLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLH 220
Cdd:pfam02353 1 SKTRDAENIQAHYDLSNDFFALFLDPTMTYSCAYFER--PDMTLEEAQQAKLDLILDKLGLKPGMTLLDIGCGWGGLMRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 221 AAKNYGVTVTGVTLSREQLAFAQARVG--GLP--VDFRLQDYRDVaDGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRP 296
Cdd:pfam02353 79 AAERYDVNVVGLTLSKNQYKLARKRVAaeGLArkVEVLLQDYRDF-DEPFDRIVSVGMFEHVGHENYDTFFKKLYNLLPP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 297 EGRLLVQQMS---RGATAPGGGA--FIESYVAPDMHMRPVGQTVDLLEQAGLEVRDVHALREHYVRTVGVWLETLEARWD 371
Cdd:pfam02353 158 GGLMLLHTITglhPDETSERGLPlkFIDKYIFPGGELPSISMIVESSSEAGFTVEDVESLRPHYAKTLDLWAENLQANKD 237
|
250 260 270
....*....|....*....|....*....|....*
gi 556037765 372 AVVALVGEPMARVWRLYLVGGALTFEEGRMGVDQI 406
Cdd:pfam02353 238 EAIALQSEEFYRMWMLYLTGCAVAFRIGYIDVHQF 272
|
|
| PRK11705 |
PRK11705 |
cyclopropane fatty acyl phospholipid synthase; |
103-396 |
4.62e-77 |
|
cyclopropane fatty acyl phospholipid synthase;
Pssm-ID: 183282 Cd Length: 383 Bit Score: 243.99 E-value: 4.62e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 103 RVGLGDKLRA-VRTLLRLgvlgpkppapdVQARIVgDLHSRERDRAAISYHYDLSNEFYALILDERMAYSCGYW--TSDa 179
Cdd:PRK11705 81 RAGLDEKLPHhLKDTLRI-----------LRARLF-NLQSKKRAWIVGKEHYDLGNDLFEAMLDPRMQYSCGYWkdADT- 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 180 pgygLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARVGGLPVDFRLQDYR 259
Cdd:PRK11705 148 ----LEEAQEAKLDLICRKLQLKPGMRVLDIGCGWGGLARYAAEHYGVSVVGVTISAEQQKLAQERCAGLPVEIRLQDYR 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 260 DVaDGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRPEGRLLVQQMSRGATAPGGGAFIESYVAPDMHMRPVGQTVDLLE 339
Cdd:PRK11705 224 DL-NGQFDRIVSVGMFEHVGPKNYRTYFEVVRRCLKPDGLFLLHTIGSNKTDTNVDPWINKYIFPNGCLPSVRQIAQASE 302
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 556037765 340 qaGLEV-RDVHALREHYVRTVGVWLETLEARWDAVVALVGEPMARVWRLYLVGGALTF 396
Cdd:PRK11705 303 --GLFVmEDWHNFGADYDRTLMAWHENFEAAWPELADNYSERFYRMWRYYLLSCAGAF 358
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
151-303 |
1.52e-68 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 214.41 E-value: 1.52e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 151 YHYDLSNEFYALILDERMAYSCGYWTSdaPGYGLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVT 230
Cdd:COG2230 1 HHYDLGNDFYRLFLDPTMTYSCAYFED--PDDTLEEAQEAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVT 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556037765 231 GVTLSREQLAFAQARV--GGLP--VDFRLQDYRDV-ADGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRPEGRLLVQ 303
Cdd:COG2230 79 GVTLSPEQLEYARERAaeAGLAdrVEVRLADYRDLpADGQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLH 156
|
|
| mycolic_MTase |
NF040660 |
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include ... |
125-405 |
2.50e-52 |
|
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include tailoring enzymes that make site-specific modifications to mycolic acid precursor molecules. These include Mycobacterium tuberculosis enzymes MmaA1-MmaA4, CmaA1-CmaA2, and PcaA. The family also includes UmaA, reported to be the lone member of this family not involved in mycolic acid biosynthesis. No members of this family are found in species that lack mycolic acids. This model excludes two more distantly related paralogs, Rv0447c (UfaA1 ) and Rv3720, that are also encoded in the Mycobacterium tuberculosis H37Rv genome.
Pssm-ID: 468626 Cd Length: 283 Bit Score: 176.88 E-value: 2.50e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 125 KPPAPDVQArivgdlhsrerdraaisyHYDLSNEFYALILDERMAYSCGYWtsDAPGYGLAEAQTDKLDLVCRKLGLEPG 204
Cdd:NF040660 2 RPHFEDVQA------------------HYDLSDDFFALFLDPTQTYSCAYF--ERDDMTLEEAQIAKIDLALGKLNLEPG 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 205 MRLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARVGGLPV----DFRLQDYRDVADgPYDAISTIEMGEHVGQ 280
Cdd:NF040660 62 MTLLDIGCGWGATMRRAVEKYDVNVVGLTLSKNQAAHVQQVLDEIDTprsrRVLLQGWEEFDE-PVDRIVSIGAFEHFGH 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 281 GQYPVFAAQLHRLLRPEGRLLVQQMS---------RGATAPGGGA----FIESYVAPDMHMRPVGQTVDLLEQAGLEVRD 347
Cdd:NF040660 141 ERYDDFFKRAYNILPADGRMLLHTITglhrkemheRGLPLTMELArfikFIVTEIFPGGRLPSIEMVVEHAEKAGFTVTR 220
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 556037765 348 VHALREHYVRTVGVWLETLEARWDAVVALVGEPMARVWRLYLVGGALTFEEGRMGVDQ 405
Cdd:NF040660 221 VQSLQPHYARTLDLWADALQAHKDEAIAIQSEEVYERYMKYLTGCAKLFRDGYIDVNQ 278
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
208-298 |
1.69e-19 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 83.00 E-value: 1.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 208 LDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARVG--GLPVDFRLQDYRD--VADGPYDAISTIEMGEHVGQGQY 283
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAeaGLNVEFVQGDAEDlpFPDGSFDLVVSSGVLHHLPDPDL 81
|
90
....*....|....*
gi 556037765 284 PVFAAQLHRLLRPEG 298
Cdd:pfam13649 82 EAALREIARVLKPGG 96
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
201-302 |
1.29e-18 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 81.22 E-value: 1.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 201 LEPGMRLLDVGCGWGALGLHAAKNyGVTVTGVTLSREQLAFAQARVGGLPVDFRLQDYRDVA--DGPYDAISTIEMGEHV 278
Cdd:COG2227 22 LPAGGRVLDVGCGTGRLALALARR-GADVTGVDISPEALEIARERAAELNVDFVQGDLEDLPleDGSFDLVICSEVLEHL 100
|
90 100
....*....|....*....|....
gi 556037765 279 gqGQYPVFAAQLHRLLRPEGRLLV 302
Cdd:COG2227 101 --PDPAALLRELARLLKPGGLLLL 122
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
175-307 |
6.50e-17 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 76.96 E-value: 6.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 175 WTSDAPGYglaeaqtDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKnYGVTVTGVTLSREQLAFAQARVG--GLPVD 252
Cdd:COG2226 1 FDRVAARY-------DGREALLAALGLRPGARVLDLGCGTGRLALALAE-RGARVTGVDISPEMLELARERAAeaGLNVE 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 556037765 253 FRLQDYRD--VADGPYDAISTIEMGEHVgqGQYPVFAAQLHRLLRPEGRLLVQQMSR 307
Cdd:COG2226 73 FVVGDAEDlpFPDGSFDLVISSFVLHHL--PDPERALAEIARVLKPGGRLVVVDFSP 127
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
169-303 |
2.48e-13 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 68.40 E-value: 2.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 169 AYSCGYWTSDAPGYglaeaqtdkLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARV-- 246
Cdd:COG0500 1 PWDSYYSDELLPGL---------AALLALLERLPKGGRVLDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARAak 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556037765 247 -GGLPVDFRLQDYRD---VADGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRPEGRLLVQ 303
Cdd:COG0500 72 aGLGNVEFLVADLAEldpLPAESFDLVVAFGVLHHLPPEEREALLRELARALKPGGVLLLS 132
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
203-303 |
7.57e-13 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 64.07 E-value: 7.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 203 PGMRLLDVGCGWGALGLHAAKNY-GVTVTGVTLSREQLAFAQARVGGlpVDFRLQDYRDVA-DGPYDAISTIEMGEHVgq 280
Cdd:COG4106 1 PPRRVLDLGCGTGRLTALLAERFpGARVTGVDLSPEMLARARARLPN--VRFVVADLRDLDpPEPFDLVVSNAALHWL-- 76
|
90 100
....*....|....*....|...
gi 556037765 281 GQYPVFAAQLHRLLRPEGRLLVQ 303
Cdd:COG4106 77 PDHAALLARLAAALAPGGVLAVQ 99
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
208-302 |
2.21e-12 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 62.68 E-value: 2.21e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 208 LDVGCGWGALGLHAAKnYGVTVTGVTLSREQLAFAQARVGGLPVDFRLQDYRDV--ADGPYDAISTIEMGEHVgqgQYPV 285
Cdd:pfam08241 1 LDVGCGTGLLTELLAR-LGARVTGVDISPEMLELAREKAPREGLTFVVGDAEDLpfPDNSFDLVLSSEVLHHV---EDPE 76
|
90
....*....|....*...
gi 556037765 286 -FAAQLHRLLRPEGRLLV 302
Cdd:pfam08241 77 rALREIARVLKPGGILII 94
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
206-303 |
3.51e-12 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 62.45 E-value: 3.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 206 RLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQ---ARVGGLPVDFRLQDYRDV---ADGPYDAISTIEMGEHVG 279
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARkaaAALLADNVEVLKGDAEELppeADESFDVIISDPPLHHLV 80
|
90 100
....*....|....*....|....
gi 556037765 280 QGQYPVFaAQLHRLLRPEGRLLVQ 303
Cdd:cd02440 81 EDLARFL-EEARRLLKPGGVLVLT 103
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
186-346 |
1.37e-11 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 63.09 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 186 EAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKnYGVTVTGVTLSREQLAFAQARvgGLPVDFRLQDYRDVA--D 263
Cdd:COG4976 29 EAPALLAEELLARLPPGPFGRVLDLGCGTGLLGEALRP-RGYRLTGVDLSEEMLAKAREK--GVYDRLLVADLADLAepD 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 264 GPYDAISTIEMGEHVGQGQyPVFAAqLHRLLRPEGRLLVQqmSRGATAPGGGAFIESYVapdmhmrpvgqtVDLLEQAGL 343
Cdd:COG4976 106 GRFDLIVAADVLTYLGDLA-AVFAG-VARALKPGGLFIFS--VEDADGSGRYAHSLDYV------------RDLLAAAGF 169
|
...
gi 556037765 344 EVR 346
Cdd:COG4976 170 EVP 172
|
|
| PLN02244 |
PLN02244 |
tocopherol O-methyltransferase |
149-314 |
1.61e-11 |
|
tocopherol O-methyltransferase
Pssm-ID: 215135 [Multi-domain] Cd Length: 340 Bit Score: 65.15 E-value: 1.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 149 ISYHYDLSNEFYALILDERMAYscGYWTSDAPGYGLAEAQTDKLDLVCRKLGL-----EPGMRLLDVGCGWGALGLHAAK 223
Cdd:PLN02244 61 IAEFYDESSGVWEDVWGEHMHH--GYYDPGASRGDHRQAQIRMIEESLAWAGVpdddeKRPKRIVDVGCGIGGSSRYLAR 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 224 NYGVTVTGVTLSREQLAFAQ--ARVGGL--PVDFRLQDYRD--VADGPYDAISTIEMGEHVgqgqypvfaaqlhrllrPE 297
Cdd:PLN02244 139 KYGANVKGITLSPVQAARANalAAAQGLsdKVSFQVADALNqpFEDGQFDLVWSMESGEHM-----------------PD 201
|
170
....*....|....*..
gi 556037765 298 GRLLVQQMSRGAtAPGG 314
Cdd:PLN02244 202 KRKFVQELARVA-APGG 217
|
|
| PLN02336 |
PLN02336 |
phosphoethanolamine N-methyltransferase |
198-344 |
3.65e-09 |
|
phosphoethanolamine N-methyltransferase
Pssm-ID: 177970 [Multi-domain] Cd Length: 475 Bit Score: 58.61 E-value: 3.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 198 KLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVTGVTLSREQLAFAQARVGGLP--VDFRLQD--YRDVADGPYDAISTIE 273
Cdd:PLN02336 261 KLDLKPGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALERAIGRKcsVEFEVADctKKTYPDNSFDVIYSRD 340
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556037765 274 MGEHVgQGQyPVFAAQLHRLLRPEGRLLVQQM--SRGATAPGGGAFIES--YvapDMH-MRPVGQtvdLLEQAGLE 344
Cdd:PLN02336 341 TILHI-QDK-PALFRSFFKWLKPGGKVLISDYcrSPGTPSPEFAEYIKQrgY---DLHdVQAYGQ---MLKDAGFD 408
|
|
| Methyltransf_12 |
pfam08242 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
208-300 |
6.20e-09 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 400515 [Multi-domain] Cd Length: 98 Bit Score: 53.14 E-value: 6.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 208 LDVGCGWGALGLH-AAKNYGVTVTGVTLSREQLAFAQARVGGLP------VDFRLQDYRDVADGPYDAISTIEMGEHVGQ 280
Cdd:pfam08242 1 LEIGCGTGTLLRAlLEALPGLEYTGLDISPAALEAARERLAALGllnavrVELFQLDLGELDPGSFDVVVASNVLHHLAD 80
|
90 100
....*....|....*....|
gi 556037765 281 GQypVFAAQLHRLLRPEGRL 300
Cdd:pfam08242 81 PR--AVLRNIRRLLKPGGVL 98
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
199-302 |
9.95e-09 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 54.81 E-value: 9.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 199 LGLEPGMRLLDVGCGWGALGLHAAKNYGV-TVTGVTLSREQLAFAQ---ARVGGLPVDFRLQD-YRDVADGPYDAIST-- 271
Cdd:COG2813 45 LPEPLGGRVLDLGCGYGVIGLALAKRNPEaRVTLVDVNARAVELARanaAANGLENVEVLWSDgLSGVPDGSFDLILSnp 124
|
90 100 110
....*....|....*....|....*....|....*.
gi 556037765 272 -IemgeHVGQGQYPVFAAQL----HRLLRPEGRLLV 302
Cdd:COG2813 125 pF----HAGRAVDKEVAHALiadaARHLRPGGELWL 156
|
|
| Methyltransf_23 |
pfam13489 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
199-345 |
3.29e-08 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 404385 [Multi-domain] Cd Length: 162 Bit Score: 52.82 E-value: 3.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 199 LGLEPGMRLLDVGCGWGALGLHAAKNyGVTVTGVTLSREQLAFAQARVGGLPVDfrlQDYRDVADGPYDAISTIEMGEHV 278
Cdd:pfam13489 18 PKLPSPGRVLDFGCGTGIFLRLLRAQ-GFSVTGVDPSPIAIERALLNVRFDQFD---EQEAAVPAGKFDVIVAREVLEHV 93
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 279 gqGQYPVFAAQLHRLLRPEGRLLVQQMSRGATAPGGGAFIEsYVAPD---MHMRPVGQTVDLLEQAGLEV 345
Cdd:pfam13489 94 --PDPPALLRQIAALLKPGGLLLLSTPLASDEADRLLLEWP-YLRPRnghISLFSARSLKRLLEEAGFEV 160
|
|
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
195-351 |
1.74e-07 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 51.69 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 195 VCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVT--VTGVTLSREQLAFAQARV----GGLPVDFRLQDYRD--VADGPY 266
Cdd:PRK00216 43 TIKWLGVRPGDKVLDLACGTGDLAIALAKAVGKTgeVVGLDFSEGMLAVGREKLrdlgLSGNVEFVQGDAEAlpFPDNSF 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 267 DAIStiemgehVGQG-----QYPVFAAQLHRLLRPEGRLLVQQMSRgATAPG----------------GGAF---IESYV 322
Cdd:PRK00216 123 DAVT-------IAFGlrnvpDIDKALREMYRVLKPGGRLVILEFSK-PTNPPlkkaydfylfkvlpliGKLIsknAEAYS 194
|
170 180 190
....*....|....*....|....*....|..
gi 556037765 323 --APDMHMRPVGQT-VDLLEQAGLEVRDVHAL 351
Cdd:PRK00216 195 ylAESIRAFPDQEElAAMLEEAGFERVRYRNL 226
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
206-311 |
2.06e-07 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 51.65 E-value: 2.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 206 RLLDVGCGWGALGLHAAKNYG-VTVTGVTLSREQLAFAQARVGGLPVDFRLQ-DYRDVADGP----YDAISTIEMGEHVg 279
Cdd:smart00828 2 RVLDFGCGYGSDLIDLAERHPhLQLHGYTISPEQAEVGRERIRALGLQGRIRiFYRDSAKDPfpdtYDLVFGFEVIHHI- 80
|
90 100 110
....*....|....*....|....*....|...
gi 556037765 280 QGQYPVFAAqLHRLLRPEGRLLVQQ-MSRGATA 311
Cdd:smart00828 81 KDKMDLFSN-ISRHLKDGGHLVLADfIANLLSA 112
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
197-302 |
5.04e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 50.32 E-value: 5.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 197 RKLGLEPGMRLLDVGCGWGALGLHAAKNYGVT--VTGVTLSREQLAFAQARV--GGLPVDFRLQD--YRDVADGPYDAIS 270
Cdd:PRK08317 13 ELLAVQPGDRVLDVGCGPGNDARELARRVGPEgrVVGIDRSEAMLALAKERAagLGPNVEFVRGDadGLPFPDGSFDAVR 92
|
90 100 110
....*....|....*....|....*....|..
gi 556037765 271 TIEMGEHVGQGQypVFAAQLHRLLRPEGRLLV 302
Cdd:PRK08317 93 SDRVLQHLEDPA--RALAEIARVLRPGGRVVV 122
|
|
| PRK14967 |
PRK14967 |
putative methyltransferase; Provisional |
179-269 |
2.06e-06 |
|
putative methyltransferase; Provisional
Pssm-ID: 184931 [Multi-domain] Cd Length: 223 Bit Score: 48.51 E-value: 2.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 179 APGYGLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGVTVTGVTLSRE--QLAFAQARVGGLPVDFRLQ 256
Cdd:PRK14967 12 APGVYRPQEDTQLLADALAAEGLGPGRRVLDLCTGSGALAVAAAAAGAGSVTAVDISRRavRSARLNALLAGVDVDVRRG 91
|
90
....*....|....
gi 556037765 257 DY-RDVADGPYDAI 269
Cdd:PRK14967 92 DWaRAVEFRPFDVV 105
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
201-303 |
3.30e-06 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 46.64 E-value: 3.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 201 LEPGMRLLDVGCGWGALGLHAAKNYG--VTVTGVTLSREQLAFAQARVGGLPVD---FRLQDYRD----VADGPYDAIST 271
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAEELGpnAEVVGIDISEEAIEKARENAQKLGFDnveFEQGDIEElpelLEDDKFDVVIS 80
|
90 100 110
....*....|....*....|....*....|..
gi 556037765 272 IEMGEHVGQGQyPVFaAQLHRLLRPEGRLLVQ 303
Cdd:pfam13847 81 NCVLNHIPDPD-KVL-QEILRVLKPGGRLIIS 110
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
206-302 |
4.42e-06 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 46.81 E-value: 4.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 206 RLLDVGCGWGALGLHAAKNYG-VTVTGVTLSREQLAFAQ--ARVGGLP-VDFRLQD-YRDVADGPYDAIST-------IE 273
Cdd:pfam05175 34 KVLDLGCGAGVLGAALAKESPdAELTMVDINARALESARenLAANGLEnGEVVASDvYSGVEDGKFDLIISnppfhagLA 113
|
90 100
....*....|....*....|....*....
gi 556037765 274 MGEHVGQGqypvFAAQLHRLLRPEGRLLV 302
Cdd:pfam05175 114 TTYNVAQR----FIADAKRHLRPGGELWI 138
|
|
| PLN02396 |
PLN02396 |
hexaprenyldihydroxybenzoate methyltransferase |
169-363 |
1.43e-05 |
|
hexaprenyldihydroxybenzoate methyltransferase
Pssm-ID: 178018 [Multi-domain] Cd Length: 322 Bit Score: 46.65 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 169 AYSCGYWTSDAPGYGLAEAQTDKLDLV----CRKLGLEP-------GMRLLDVGCGWGALGLHAAKnYGVTVTGVTLSRE 237
Cdd:PLN02396 86 AIADTWWHSEGPFKPLHQMNPTRLAFIrstlCRHFSKDPssakpfeGLKFIDIGCGGGLLSEPLAR-MGATVTGVDAVDK 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 238 QLAFAQARVGGLPVDFRLQDYRDVADG------PYDAISTIEMGEHVGQgqyPV-FAAQLHRLLRPEGRLLVQQMSRG-- 308
Cdd:PLN02396 165 NVKIARLHADMDPVTSTIEYLCTTAEKladegrKFDAVLSLEVIEHVAN---PAeFCKSLSALTIPNGATVLSTINRTmr 241
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556037765 309 --ATAPGGGAFI-----------ESYVAPDmhmrpvgQTVDLLEQAGLEVRDVHALRehYVRTVGVWL 363
Cdd:PLN02396 242 ayASTIVGAEYIlrwlpkgthqwSSFVTPE-------ELSMILQRASVDVKEMAGFV--YNPITGRWL 300
|
|
| COG4627 |
COG4627 |
Predicted SAM-depedendent methyltransferase [General function prediction only]; |
261-371 |
2.44e-04 |
|
Predicted SAM-depedendent methyltransferase [General function prediction only];
Pssm-ID: 443666 [Multi-domain] Cd Length: 161 Bit Score: 41.39 E-value: 2.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 261 VADGPYDAISTIEMGEHVGQGQYPVFAAQLHRLLRPEGRLLVqqmsrgaTAPGGGAFIESYVAPDMHMRPVGQTVDLLEQ 340
Cdd:COG4627 42 FPDNSVDAIYSSHVLEHLDYEEAPLALKECYRVLKPGGILRI-------VVPDLEHVARLYLAEYDAALDVAELRLAGPI 114
|
90 100 110
....*....|....*....|....*....|.
gi 556037765 341 AGLEVRDVHALREHYVRTVGVWLETLEARWD 371
Cdd:COG4627 115 DPLGIILGERLAGLAARHSVLFRTGFTRLAL 145
|
|
| Gcd14 |
COG2519 |
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ... |
198-307 |
7.92e-04 |
|
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442009 [Multi-domain] Cd Length: 249 Bit Score: 40.91 E-value: 7.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 198 KLGLEPGMRLLDVGCGWGALG---LHAAKNYGvTVTGVTLSREQLAFAQARVG--GLP--VDFRLQDYRDVAD-GPYDAI 269
Cdd:COG2519 86 RLDIFPGARVLEAGTGSGALTlalARAVGPEG-KVYSYERREDFAEIARKNLErfGLPdnVELKLGDIREGIDeGDVDAV 164
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 556037765 270 sTIEMGEhvgqgqyPVFA-AQLHRLLRPEGRLL-----VQQMSR 307
Cdd:COG2519 165 -FLDMPD-------PWEAlEAVAKALKPGGVLVayvptVNQVSK 200
|
|
| PRK07580 |
PRK07580 |
Mg-protoporphyrin IX methyl transferase; Validated |
198-269 |
1.22e-03 |
|
Mg-protoporphyrin IX methyl transferase; Validated
Pssm-ID: 236059 [Multi-domain] Cd Length: 230 Bit Score: 40.21 E-value: 1.22e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556037765 198 KLGLEPGMRLLDVGCGWGALGLHAAKNyGVTVTGVTLSREQLAFAQARV--GGLP--VDFRLQDYRDVAdGPYDAI 269
Cdd:PRK07580 58 ADGDLTGLRILDAGCGVGSLSIPLARR-GAKVVASDISPQMVEEARERApeAGLAgnITFEVGDLESLL-GRFDTV 131
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
201-269 |
3.26e-03 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 38.99 E-value: 3.26e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556037765 201 LEPGMRLLDVGCGWGALGLHAAKNY-GVTVTGVTLSREQLAFAQ---ARVGGLPVDFRLQD-YRDVADGPYDAI 269
Cdd:PRK09328 106 LKEPLRVLDLGTGSGAIALALAKERpDAEVTAVDISPEALAVARrnaKHGLGARVEFLQGDwFEPLPGGRFDLI 179
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
202-269 |
4.95e-03 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 37.96 E-value: 4.95e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556037765 202 EPGMRLLDVGCGWGALGLHAAKNyGVTVTGVTLSRE--QLAFAQARVGGL---PVDFRLQD-YRDVADGPYDAI 269
Cdd:PRK14968 22 KKGDRVLEVGTGSGIVAIVAAKN-GKKVVGVDINPYavECAKCNAKLNNIrnnGVEVIRSDlFEPFRGDKFDVI 94
|
|
| PCMT |
pfam01135 |
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); |
178-302 |
6.04e-03 |
|
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
Pssm-ID: 395902 [Multi-domain] Cd Length: 205 Bit Score: 37.73 E-value: 6.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556037765 178 DAP---GYGLAEAQTDKLDLVCRKLGLEPGMRLLDVGCGWGALGLHAAKNYGV--TVTGVTLSREQLAFAQARVGGLPVD 252
Cdd:pfam01135 45 DIPlsiGYGQTISAPHMHAMMLELLELKPGMRVLEIGSGSGYLTACFARMVGEvgRVVSIEHIPELVEIARRNLEKLGLE 124
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556037765 253 ---FRlqdyrdVADG--------PYDAIstiemgeHVGQGQyPVFAAQLHRLLRPEGRLLV 302
Cdd:pfam01135 125 nviVV------VGDGrqgwpefaPYDAI-------HVGAAA-PEIPEALIDQLKEGGRLVI 171
|
|
| |
