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Conserved domains on  [gi|484576765|gb|AGK53563|]
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TrkA-N domain-containing protein [Bacillus sp. 1NLA3E]

Protein Classification

potassium channel family protein( domain architecture ID 11426271)

potassium channel family protein spans the cell membrane to form a conduction pathway or pore, through which selective ions such as potassium, sodium, and calcium translocate across cell membranes, similar to Trk system potassium uptake protein TrkA

CATH:  1.20.5.870|3.30.70.1450|3.40.50.720
Gene Ontology:  GO:0016020|GO:0022857|GO:0030001|GO:0034220
PubMed:  15816170|9525859|11836519|1772658|11178249
SCOP:  4000005|4000027
TCDB:  1.A.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 17-312 3.50e-64

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


:

Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 204.92  E-value: 3.50e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  17 IITGTLGFMWTEKLSLFDSIWLSAVSILTIGYGDIAPVTLYGKIFTLIIIPVAIGLVTYILAQFASSIIDGNLAREVKKR 96
Cdd:COG0569    6 LLLVLLFAMGIEGLVLLDALYGLLITLTTVTTLGGGLLDPVTLVAAIFLIGVVIIPLGYTLITFGDAVLFGGLLEALRRR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  97 MMDKKINKLKNHIIICGYGRVGRQVVSQLQNENKSFVIIEKNVDVIDSFPDY-CLYIFGDAKEEQTLFDAGIDKASSIIL 175
Cdd:COG0569   86 RMERGIKKLKMHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEdVLVIVGDATDEEVLEEAGIEDADAVIA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 176 TLPDDADNLFITLTAKGINsSIQTISRAENNHSEKILYQAGVDTVINTSNIGGKRMAMSVLKPHSVEYVDTLlhnnDEAY 255
Cdd:COG0569  166 ATGDDEANILACLLAKELG-VPRIIARANDPEYADLLERLGADVVISPERLAARRIARLLLRPGVLDVLELA----DGDA 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 484576765 256 SLEEIKISSSSPLVNSSLKESKIREIFGVSIVAIKRNNHVIsNPKADEQIQAHDLII 312
Cdd:COG0569  241 EIVEVTVPEGSPLVGKTLKELDLRERYGVTVVAIKRGGEVI-IPSGDTVLEAGDELI 296
 
Name Accession Description Interval E-value
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 17-312 3.50e-64

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 204.92  E-value: 3.50e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  17 IITGTLGFMWTEKLSLFDSIWLSAVSILTIGYGDIAPVTLYGKIFTLIIIPVAIGLVTYILAQFASSIIDGNLAREVKKR 96
Cdd:COG0569    6 LLLVLLFAMGIEGLVLLDALYGLLITLTTVTTLGGGLLDPVTLVAAIFLIGVVIIPLGYTLITFGDAVLFGGLLEALRRR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  97 MMDKKINKLKNHIIICGYGRVGRQVVSQLQNENKSFVIIEKNVDVIDSFPDY-CLYIFGDAKEEQTLFDAGIDKASSIIL 175
Cdd:COG0569   86 RMERGIKKLKMHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEdVLVIVGDATDEEVLEEAGIEDADAVIA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 176 TLPDDADNLFITLTAKGINsSIQTISRAENNHSEKILYQAGVDTVINTSNIGGKRMAMSVLKPHSVEYVDTLlhnnDEAY 255
Cdd:COG0569  166 ATGDDEANILACLLAKELG-VPRIIARANDPEYADLLERLGADVVISPERLAARRIARLLLRPGVLDVLELA----DGDA 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 484576765 256 SLEEIKISSSSPLVNSSLKESKIREIFGVSIVAIKRNNHVIsNPKADEQIQAHDLII 312
Cdd:COG0569  241 EIVEVTVPEGSPLVGKTLKELDLRERYGVTVVAIKRGGEVI-IPSGDTVLEAGDELI 296
TrkA_N pfam02254
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ...
 109-222 8.51e-30

TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.


Pssm-ID: 426679 [Multi-domain]  Cd Length: 115  Bit Score: 109.92  E-value: 8.51e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  109 IIICGYGRVGRQVVSQLQnENKSFVIIEKNVDVIDSF-PDYCLYIFGDAKEEQTLFDAGIDKASSIILTLPDDADNLFIT 187
Cdd:pfam02254   1 IIIIGYGRVGRSLAEELS-EGGDVVVIDKDEERVEELrEEGVPVVVGDATDEEVLEEAGIEEADAVIAATGDDEANILIV 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 484576765  188 LTAKGINSSIQTISRAENNHSEKILYQAGVDTVIN 222
Cdd:pfam02254  80 LLARELNPDKKIIARANDPEHAELLRRLGADHVIS 114
PRK10537 PRK10537
voltage-gated potassium channel protein;
30-233 9.29e-22

voltage-gated potassium channel protein;


Pssm-ID: 236711 [Multi-domain]  Cd Length: 393  Bit Score: 94.70  E-value: 9.29e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  30 LSLFDSIWLSAVSILTIGYGDIAPVTLYGKIFTLIIIPVAIGLVTYILAQFASSIIDGNLAREVKKRmmdKKINKLKNHI 109
Cdd:PRK10537 167 ESLSTAFYFSIVTMSTVGYGDIVPVSESARLFTISVIILGITVFATSISAIFGPVIRGNLKRLVKGR---ISHMHRKDHF 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 110 IICGYGRVGRQVVSQLQNENKSFVIIeKNVDVIDSFPDYCLYIFGDAKEEQTLFDAGIDKASSIILTLPDDADNLFITLT 189
Cdd:PRK10537 244 IICGHSPLAINTYLGLRQRGQAVTVI-VPLGLEHRLPDDADLIPGDSSDSAVLKKAGAARARAILALRDNDADNAFVVLA 322

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 484576765 190 AKGINSSIQTISRAENN-HSEKIlYQAGVDTVINTSNIGGKRMAM 233
Cdd:PRK10537 323 AKEMSSDVKTVAAVNDSkNLEKI-KRVHPDMIFSPQLLGSELLAR 366
 
Name Accession Description Interval E-value
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 17-312 3.50e-64

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 204.92  E-value: 3.50e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  17 IITGTLGFMWTEKLSLFDSIWLSAVSILTIGYGDIAPVTLYGKIFTLIIIPVAIGLVTYILAQFASSIIDGNLAREVKKR 96
Cdd:COG0569    6 LLLVLLFAMGIEGLVLLDALYGLLITLTTVTTLGGGLLDPVTLVAAIFLIGVVIIPLGYTLITFGDAVLFGGLLEALRRR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  97 MMDKKINKLKNHIIICGYGRVGRQVVSQLQNENKSFVIIEKNVDVIDSFPDY-CLYIFGDAKEEQTLFDAGIDKASSIIL 175
Cdd:COG0569   86 RMERGIKKLKMHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEdVLVIVGDATDEEVLEEAGIEDADAVIA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 176 TLPDDADNLFITLTAKGINsSIQTISRAENNHSEKILYQAGVDTVINTSNIGGKRMAMSVLKPHSVEYVDTLlhnnDEAY 255
Cdd:COG0569  166 ATGDDEANILACLLAKELG-VPRIIARANDPEYADLLERLGADVVISPERLAARRIARLLLRPGVLDVLELA----DGDA 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 484576765 256 SLEEIKISSSSPLVNSSLKESKIREIFGVSIVAIKRNNHVIsNPKADEQIQAHDLII 312
Cdd:COG0569  241 EIVEVTVPEGSPLVGKTLKELDLRERYGVTVVAIKRGGEVI-IPSGDTVLEAGDELI 296
Kch COG1226
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];
60-237 1.04e-31

Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];


Pssm-ID: 440839 [Multi-domain]  Cd Length: 279  Bit Score: 119.83  E-value: 1.04e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  60 IFTLIIIPVAIGLVTYILAQFASSIIDGNLAREVKKRMMDKKINKLKNHIIICGYGRVGRQVVSQLQNENKSFVIIEKNV 139
Cdd:COG1226   78 ALLLLLVLLLLLLLLLLLLLLALLLLLLALAAREEEAEAAEDAIDLEGHVIIAGFGRVGQIVARLLRAEGIPFVVIDLDP 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 140 DVIDS-----FPdyclYIFGDAKEEQTLFDAGIDKASSIILTLPDDADNLFITLTAKGINSSIQTISRAEN-NHSEKiLY 213
Cdd:COG1226  158 ERVEElrrfgIK----VYYGDATRPDVLEAAGIERARALVVAIDDPEAALRIVELARELNPDLKIIARARDrEHAEE-LR 232

                        170       180
                 ....*....|....*....|....
gi 484576765 214 QAGVDTVINTSNIGGKRMAMSVLK 237
Cdd:COG1226  233 QAGADEVVRETFESALQLARHALE 256
TrkA_N pfam02254
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ...
 109-222 8.51e-30

TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.


Pssm-ID: 426679 [Multi-domain]  Cd Length: 115  Bit Score: 109.92  E-value: 8.51e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  109 IIICGYGRVGRQVVSQLQnENKSFVIIEKNVDVIDSF-PDYCLYIFGDAKEEQTLFDAGIDKASSIILTLPDDADNLFIT 187
Cdd:pfam02254   1 IIIIGYGRVGRSLAEELS-EGGDVVVIDKDEERVEELrEEGVPVVVGDATDEEVLEEAGIEEADAVIAATGDDEANILIV 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 484576765  188 LTAKGINSSIQTISRAENNHSEKILYQAGVDTVIN 222
Cdd:pfam02254  80 LLARELNPDKKIIARANDPEHAELLRRLGADHVIS 114
PRK10537 PRK10537
voltage-gated potassium channel protein;
30-233 9.29e-22

voltage-gated potassium channel protein;


Pssm-ID: 236711 [Multi-domain]  Cd Length: 393  Bit Score: 94.70  E-value: 9.29e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  30 LSLFDSIWLSAVSILTIGYGDIAPVTLYGKIFTLIIIPVAIGLVTYILAQFASSIIDGNLAREVKKRmmdKKINKLKNHI 109
Cdd:PRK10537 167 ESLSTAFYFSIVTMSTVGYGDIVPVSESARLFTISVIILGITVFATSISAIFGPVIRGNLKRLVKGR---ISHMHRKDHF 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 110 IICGYGRVGRQVVSQLQNENKSFVIIeKNVDVIDSFPDYCLYIFGDAKEEQTLFDAGIDKASSIILTLPDDADNLFITLT 189
Cdd:PRK10537 244 IICGHSPLAINTYLGLRQRGQAVTVI-VPLGLEHRLPDDADLIPGDSSDSAVLKKAGAARARAILALRDNDADNAFVVLA 322

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 484576765 190 AKGINSSIQTISRAENN-HSEKIlYQAGVDTVINTSNIGGKRMAM 233
Cdd:PRK10537 323 AKEMSSDVKTVAAVNDSkNLEKI-KRVHPDMIFSPQLLGSELLAR 366
trkA PRK09496
Trk system potassium transporter TrkA;
108-325 3.36e-16

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 79.01  E-value: 3.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 108 HIIICGYGRVGRQVVSQLQNENKSFVIIEKNVDVIDSFPDY--CLYIFGDAKEEQTLFDAGIDKASSIILTLPDDADNLF 185
Cdd:PRK09496   2 KIIIVGAGQVGYTLAENLSGENNDVTVIDTDEERLRRLQDRldVRTVVGNGSSPDVLREAGAEDADLLIAVTDSDETNMV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 186 ITLTAKGINSSIQTISRAENNH---SEKILYQA--GVDTVINTSNIGGKRMAMSVLKPHSVEYVDTLlhnnDEAYSLEEI 260
Cdd:PRK09496  82 ACQIAKSLFGAPTTIARVRNPEyaeYDKLFSKEalGIDLLISPELLVAREIARLIEYPGALDVEEFA----DGRVQLVEV 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 484576765 261 KISSSSPLVNSSLKEskIREIF---GVSIVAIKRNNHVISnPKADEQIQAHDLIIVFGAEDQMKIFEK 325
Cdd:PRK09496 158 KVYEGSPLVGKPLSD--LREHFpdiDVRVVAIFRGGRLII-PRGDTVIEAGDEVYFIGAREHIRAVMS 222
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 16-86 4.11e-13

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 63.83  E-value: 4.11e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 484576765   16 TIITGTLGFMWTE--KLSLFDSIWLSAVSILTIGYGDIAPVTLYGKIFTLIIIPVAIGLVTYILAQFASSIID 86
Cdd:pfam07885   6 VLIFGTVYYLLEEgwEWSFLDALYFSFVTLTTVGYGDIVPLTDAGRLFTIFYILIGIPLFAIFLAVLGRFLTE 78
trkA PRK09496
Trk system potassium transporter TrkA;
100-314 1.73e-11

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 64.76  E-value: 1.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 100 KKINKLKNHIIICGYGRVGRQVVSQLQNENKSFVIIEKN----VDVIDSFPDyCLYIFGDAKEEQTLFDAGIDKASSIIL 175
Cdd:PRK09496 225 GRLEKPVKRVMIVGGGNIGYYLAKLLEKEGYSVKLIERDperaEELAEELPN-TLVLHGDGTDQELLEEEGIDEADAFIA 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 176 TLPDDADNLFITLTAK--GINSSIQTISRAENnhsEKILYQAGVDTVINtsniggKRMAM--SVLKpH----SVEYVDTL 247
Cdd:PRK09496 304 LTNDDEANILSSLLAKrlGAKKVIALVNRPAY---VDLVEGLGIDIAIS------PRQATasEILR-HvrrgDIVAVHSL 373

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 484576765 248 LHNNDEAYsleEIKISSSSPLVNSSLKESKIREifGVSIVAIKRNNHVISnPKADEQIQAHDLIIVF 314
Cdd:PRK09496 374 RRGAAEAI---EAVAHETSKVVGKPLKDLKLPK--GVLIGAIVRGGEVII-PTGDTVIEPGDHVIVF 434
KhtT COG0490
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) ...
 230-325 3.31e-11

K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440256 [Multi-domain]  Cd Length: 140  Bit Score: 60.32  E-value: 3.31e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 230 RMAMSVLKPHSVEYVDTLLHNNDEAYSLEEIKISSSSPLVNSSLKESKIREIFGVSIVAIKRNNHVISNPKADEQIQAHD 309
Cdd:COG0490   43 LALLLLLLGELLRLLTRLLIELVLLLAIEEVKVPPGSPLVGKTLGELNLRQRTGVTVVAIRRGGEVILSPGPDTVLEAGD 122

                         90
                 ....*....|....*.
gi 484576765 310 LIIVFGAEDQMKIFEK 325
Cdd:COG0490  123 TLVVVGTREQLERLEE 138
COG3273 COG3273
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only];
273-327 3.89e-08

Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only];


Pssm-ID: 442504 [Multi-domain]  Cd Length: 387  Bit Score: 54.29  E-value: 3.89e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 484576765 273 LKESKIREIFGVSIVAIKRNNHVISNPKADEQIQAHDLIIVFGAEDQMKIFEKVA 327
Cdd:COG3273  331 LGELKLETETGVRVIAIRRGGGWIYDPDGDTRLRAGDVLIVKGTREGLERLEELA 385
TrkA_C pfam02080
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ...
 273-325 1.55e-07

TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.


Pssm-ID: 460440 [Multi-domain]  Cd Length: 70  Bit Score: 47.99  E-value: 1.55e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 484576765  273 LKESKIREIFGVSIVAIKRNNHVISnPKADEQIQAHDLIIVFGAEDQMKIFEK 325
Cdd:pfam02080  17 LKELNLPERFGVRIVAIRRGGRLII-PSGDTVLEAGDRLLVIGTPDDLAALRE 68
PRK10669 PRK10669
putative cation:proton antiport protein; Provisional
 107-236 1.85e-07

putative cation:proton antiport protein; Provisional


Pssm-ID: 182633 [Multi-domain]  Cd Length: 558  Bit Score: 52.41  E-value: 1.85e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 107 NHIIICGYGRVGRQVVSQLQNENKSFVIIEKNVDVIDSFPDYCL-YIFGDAKEEQTLFDAGIDKASSIILTLPDDADNLF 185
Cdd:PRK10669 418 NHALLVGYGRVGSLLGEKLLAAGIPLVVIETSRTRVDELRERGIrAVLGNAANEEIMQLAHLDCARWLLLTIPNGYEAGE 497

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 484576765 186 ITLTAKGINSSIQTISRAENNHSEKILYQAGVDTVIntsnIGGKRMAMSVL 236
Cdd:PRK10669 498 IVASAREKRPDIEIIARAHYDDEVAYITERGANQVV----MGEREIARTML 544
PRK03562 PRK03562
glutathione-regulated potassium-efflux system protein KefC; Provisional
 89-236 3.55e-07

glutathione-regulated potassium-efflux system protein KefC; Provisional


Pssm-ID: 235131 [Multi-domain]  Cd Length: 621  Bit Score: 51.53  E-value: 3.55e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765  89 LAREVKKRMMDKK----INKLKNHIIICGYGRVGRQVVSQLQNENKSFVIIEKNVDVIDSFPDYCLYIF-GDAKEEQTLF 163
Cdd:PRK03562 379 LDRLEQSRTEEAReadeIDEQQPRVIIAGFGRFGQIVGRLLLSSGVKMTVLDHDPDHIETLRKFGMKVFyGDATRMDLLE 458

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 484576765 164 DAGIDKASSIILTLPDDADNLFITLTAKGINSSIQTISRAEN-NHSEKiLYQAGVDTVINTSNIGGKRMAMSVL 236
Cdd:PRK03562 459 SAGAAKAEVLINAIDDPQTSLQLVELVKEHFPHLQIIARARDvDHYIR-LRQAGVEKPERETFEGALKSGRLVL 531
PRK03659 PRK03659
glutathione-regulated potassium-efflux system protein KefB; Provisional
 109-218 8.44e-05

glutathione-regulated potassium-efflux system protein KefB; Provisional


Pssm-ID: 179625 [Multi-domain]  Cd Length: 601  Bit Score: 44.25  E-value: 8.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484576765 109 IIICGYGRVGrQVVSQLQNENKSFV-IIEKNVDVIDSFPDYCLYIF-GDAKEEQTLFDAGIDKASSIILTLPDDADNLFI 186
Cdd:PRK03659 403 VIIVGFGRFG-QVIGRLLMANKMRItVLERDISAVNLMRKYGYKVYyGDATQLELLRAAGAEKAEAIVITCNEPEDTMKI 481

                         90       100       110
                 ....*....|....*....|....*....|..
gi 484576765 187 TLTAKGINSSIQTISRAENNHSEKILYQAGVD 218
Cdd:PRK03659 482 VELCQQHFPHLHILARARGRVEAHELLQAGVT 513
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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