|
Name |
Accession |
Description |
Interval |
E-value |
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
1-918 |
0e+00 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 1749.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 1 MDKTYQPASIETQWYQTWEKNGYFKPS--GKGDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTD 78
Cdd:COG0525 3 LPKTYDPKEVEAKWYQYWEENGYFKADpdSDKEPFTIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWQPGTD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 79 HAGIATQMVVERLLDAEGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLY 158
Cdd:COG0525 83 HAGIATQAVVERQLAEEGKSRHDLGREKFLERVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVFVRLY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 159 KDGLIYRGKRLVNWDPKLHTAVSDLEVISEEEKGFLWHFRYPLADGSGHIVVATTRPETMLGDTAVAVHPEDERYQQLVG 238
Cdd:COG0525 163 EKGLIYRGKRLVNWDPKLKTALSDLEVEHEEVKGHLWHIRYPLADGSGYIVVATTRPETMLGDTAVAVHPEDERYKHLIG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 239 KMIKLPLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNDDvPEKYRGMERFAARKQI 318
Cdd:COG0525 243 KTVILPLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKRHNLPMINILDEDGTINEN-AGKYRGLDRFEARKAI 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 319 VADFEALGLLEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEDGDIKFVPQQYENMYFSWMRDIQDWC 398
Cdd:COG0525 322 VADLEELGLLVKVEPHKHSVGHSDRSGTVIEPYLSDQWFVKMKPLAKPAIEAVEDGEIKFVPERWEKTYFHWMENIRDWC 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 399 ISRQLWWGHRIPAWYDAEGNIYVGRSEADVRAENnlpDDLELKQDDDVLDTWFSSGLWTFGTLGWPENTEELKTFHPTDV 478
Cdd:COG0525 402 ISRQLWWGHRIPAWYCPDGEVYVARTEPEACAKA---GSVNLTQDEDVLDTWFSSALWPFSTLGWPEKTEDLKYFYPTSV 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 479 LVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDgidleslvakrtagmmqphl 558
Cdd:COG0525 479 LVTGFDIIFFWVARMIMMGLHFTGEVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLDLID-------------------- 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 559 rdkiekqtrkefpdginAYGTDALRYTYYSLASTGRDIKFDVGRIEGFRNFCNKIWNATNYVLMNCEDQDCGADGSADyE 638
Cdd:COG0525 539 -----------------KYGADALRFTLAALASPGRDIKFDEERVEGYRNFANKLWNASRFVLMNLEGFDPGLDPDPE-E 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 639 LSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDDNasAAQKKGTRRTLIRVLEVIL 718
Cdd:COG0525 601 LSLADRWILSRLNKTIAEVTEALEKYRFDEAAQALYDFVWNEFCDWYLELAKPRLYGGD--EAAKRETRATLVYVLEQIL 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 719 RLAHPLMPFITEEIWQKVKTlaGQSGDTIMHQPYPVADTSKIDAAAIADLEWIKQAVVAVRNIRGEMNIAPGKAIPVLVV 798
Cdd:COG0525 679 RLLHPFMPFITEEIWQKLPP--RKEGESIMLAPWPEADEELIDEEAEAEFEWLKEVISAIRNIRAEMNIPPSKKLPLLLK 756
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 799 NANTDDLRRIEENRPFLTKLANLESIAPLEGEAP-MSATALVGKMELLVPMAGLIDTAAELARLDKEIEKLTKEVVKTEG 877
Cdd:COG0525 757 GADEADRARLEENAAYIKRLARLEEITILVDEKPeGAASAVVGGAEVFLPLEGLIDVEAERARLEKELAKLEKEIARVEK 836
|
890 900 910 920
....*....|....*....|....*....|....*....|.
gi 409026056 878 KLNNPKFVDKAPTEVVDKERERLADFQASIAKLTEQKAKMA 918
Cdd:COG0525 837 KLSNEGFVAKAPAEVVEKEREKLAEAEAKLEKLEEQLARLK 877
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
1-919 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 1672.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 1 MDKTYQPASIETQWYQTWEKNGYFKPSG-KGDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDH 79
Cdd:PRK05729 5 LPKTYDPKEVEAKWYQKWEEKGYFKPDDnSKKPFSIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWLPGTDH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 80 AGIATQMVVERLLDAEGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYK 159
Cdd:PRK05729 85 AGIATQMVVERQLAAEGKSRHDLGREKFLEKVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVFVRLYE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 160 DGLIYRGKRLVNWDPKLHTAVSDLEVISEEEKGFLWHFRYPLADGSGHIVVATTRPETMLGDTAVAVHPEDERYQQLVGK 239
Cdd:PRK05729 165 KGLIYRGKRLVNWDPKLQTALSDLEVEYKEVKGKLWHIRYPLADGSDYLVVATTRPETMLGDTAVAVNPEDERYKHLIGK 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 240 MIKLPLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNDDvPEKYRGMERFAARKQIV 319
Cdd:PRK05729 245 TVILPLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKRHNLPMINIMDEDGTINEN-PGEYQGLDRFEARKAIV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 320 ADFEALGLLEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEDGDIKFVPQQYENMYFSWMRDIQDWCI 399
Cdd:PRK05729 324 ADLEELGLLVKIEPHTHSVGHSDRSGVVIEPYLSDQWFVKMKPLAKPALEAVENGEIKFVPERWEKTYFHWMENIQDWCI 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 400 SRQLWWGHRIPAWYDAEGNIYVGRSEADVRAENNlpddleLKQDDDVLDTWFSSGLWTFGTLGWPENTEELKTFHPTDVL 479
Cdd:PRK05729 404 SRQLWWGHRIPAWYDEDGEVYVGREEPEAREKAL------LTQDEDVLDTWFSSALWPFSTLGWPEKTEDLKRFYPTSVL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 480 VTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDgidleslvakrtagmmqphlr 559
Cdd:PRK05729 478 VTGFDIIFFWVARMIMMGLHFTGQVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLDLID--------------------- 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 560 dkiekqtrkefpdginAYGTDALRYTYYSLASTGRDIKFDVGRIEGFRNFCNKIWNATNYVLMNCEDQDCGADGSADyEL 639
Cdd:PRK05729 537 ----------------KYGADALRFTLAALASPGRDIRFDEERVEGYRNFANKLWNASRFVLMNLEGADVGELPDPE-EL 599
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 640 SLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDdnasaAQKKGTRRTLIRVLEVILR 719
Cdd:PRK05729 600 SLADRWILSRLNRTVAEVTEALDKYRFDEAARALYEFIWNEFCDWYLELAKPVLQE-----AAKRATRATLAYVLEQILR 674
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 720 LAHPLMPFITEEIWQKVKTLAGQsgDTIMHQPYPVADTSKiDAAAIADLEWIKQAVVAVRNIRGEMNIAPGKAIPVLVVN 799
Cdd:PRK05729 675 LLHPFMPFITEELWQKLAPLGIE--ESIMLAPWPEADEAI-DEAAEAEFEWLKELITAIRNIRAEMNIPPSKKLPLLLKG 751
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 800 ANTDDLRRIEENRPFLTKLANLESI---APLEGEAPMSATALVGKMELLVPMAGLIDTAAELARLDKEIEKLTKEVVKTE 876
Cdd:PRK05729 752 ADAEDRARLEANEAYIKRLARLESLeilADDEEAPEGAASAVVGGAELFLPLEGLIDVEAELARLEKELAKLEKEIERVE 831
|
890 900 910 920
....*....|....*....|....*....|....*....|...
gi 409026056 877 GKLNNPKFVDKAPTEVVDKERERLADFQASIAKLTEQKAKMAA 919
Cdd:PRK05729 832 KKLSNEGFVAKAPEEVVEKEREKLAEYEEKLAKLKERLARLKA 874
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
1-901 |
0e+00 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 1262.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 1 MDKTYQPASIETQWYQTWEKNGYFKPSGKGD--PYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTD 78
Cdd:TIGR00422 1 MPKDYDPHEVEKKWYKKWEKSGFFKPDGNSNkpPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGTD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 79 HAGIATQMVVERLLDAEGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLY 158
Cdd:TIGR00422 81 HAGIATQVKVEKKLGAEGKTKHDLGREEFREKIWEWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKEAFVRLY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 159 KDGLIYRGKRLVNWDPKLHTAVSDLEVISEEEKGFLWHFRYPLADGS-GHIVVATTRPETMLGDTAVAVHPEDERYQQLV 237
Cdd:TIGR00422 161 EKGLIYRGEYLVNWDPKLNTAISDIEVEYKEVKGKLYYIRYPLANGSkDYLVVATTRPETMFGDTAVAVHPEDERYKHLI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 238 GKMIKLPLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNDDVPeKYRGMERFAARKQ 317
Cdd:TIGR00422 241 GKKVILPLTGRKIPIIADEYVDMEFGTGAVKVTPAHDFNDYEWGKRHNLEFINILDEDGLLNENAG-KYQGLTRFEARKK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 318 IVADFEALGLLEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEDGDIKFVPQQYENMYFSWMRDIQDW 397
Cdd:TIGR00422 320 IVEDLKEEGLLVKIEPHTHNVGTCWRSGTVVEPLLSKQWFVKVEKLADKALEAAEEGEIKFVPKRMEKRYLNWLRNIKDW 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 398 CISRQLWWGHRIPAWY-DAEGNIYVGRSEADVRAENNLPDDLELKQDDDVLDTWFSSGLWTFGTLGWPENTEELKTFHPT 476
Cdd:TIGR00422 400 CISRQLIWGHRIPVWYcKECGEVYVAKEEPLPDDKTNTGPSVELEQDTDVLDTWFSSSLWPFSTLGWPDETKDLKKFYPT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 477 DVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDgidleslvakrtagmmqp 556
Cdd:TIGR00422 480 DLLVTGYDIIFFWVARMIFRSLALTGQVPFKEVYIHGLVRDEQGRKMSKSLGNVIDPLDVIE------------------ 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 557 hlrdkiekqtrkefpdginAYGTDALRYTYYSLASTGRDIKFDVGRIEGFRNFCNKIWNATNYVLMNCEDQDCGADGsaD 636
Cdd:TIGR00422 542 -------------------KYGADALRFTLASLVTPGDDINFDWKRVESARNFLNKLWNASRFVLMNLSDDLELSGG--E 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 637 YELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDDNasAAQKKGTRRTLIRVLEV 716
Cdd:TIGR00422 601 EKLSLADRWILSKLNRTIKEVRKALDKYRFAEAAKALYEFIWNDFCDWYIELVKYRLYNGN--EAEKKAARDTLYYVLDK 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 717 ILRLAHPLMPFITEEIWQKVKtlagQSGDTIMHQPYPVADTSKIDAAAIADLEWIKQAVVAVRNIRGEMNIAPGKAIPVL 796
Cdd:TIGR00422 679 ALRLLHPFMPFITEEIWQHFK----EGADSIMLQSYPVVDAEFVDEEAEKAFELLKEIIVSIRNLKAESNIPPNAPLKVL 754
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 797 VVNANTDDLRRIEENRPFLTKLANLESIAPLEG--EAPMSATALVGKMELLVPMAGLIDTAAELARLDKEIEKLTKEVVK 874
Cdd:TIGR00422 755 LIYTEAETAERLKLNAVDIKGAINFSEVEVVIEkpEVTEAVVELVPGFEIIIPVKGLINKAKELARLQKQLDKEKKEVIR 834
|
890 900
....*....|....*....|....*..
gi 409026056 875 TEGKLNNPKFVDKAPTEVVDKERERLA 901
Cdd:TIGR00422 835 IEGKLENEGFVKKAPKEVIEKEKEKLE 861
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
1-920 |
0e+00 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 1081.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 1 MDKTYQPASIETQWYQTWEKNGYFKPS------GKGDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQ 74
Cdd:PTZ00419 24 MAASYDPKEVESGWYEWWEKSGFFKPAedakslNSGKKFVIVLPPPNVTGYLHIGHALTGAIQDSLIRYHRMKGDETLWV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 75 VGTDHAGIATQMVVER-LLDAEGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEV 153
Cdd:PTZ00419 104 PGTDHAGIATQVVVEKkLMKEENKTRHDLGREEFLKKVWEWKDKHGNNICNQLRRLGSSLDWSREVFTMDEQRSKAVKEA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 154 FIQLYKDGLIYRGKRLVNWDPKLHTAVSDLEVISEE----------------EKGFLWHFRYPLAD-GSGHIVVATTRPE 216
Cdd:PTZ00419 184 FVRLYEDGLIYRDTRLVNWCCYLKTAISDIEVEFEEiekptkitipgydkkvEVGVLWHFAYPLEDsGQEEIVVATTRIE 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 217 TMLGDTAVAVHPEDERYQQLVGKMIKLPLT-DREIPIIADD-YVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTD 294
Cdd:PTZ00419 264 TMLGDVAVAVHPKDERYKKLHGKELIHPFIpDRKIPIIADDeLVDMEFGTGAVKITPAHDPNDYEIAKRHNLPFINIFTL 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 295 DADLNDDVPEkYRGMERFAARKQIVADFEALGLLEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEDG 374
Cdd:PTZ00419 344 DGKINENGGE-FAGMHRFDCRRKIEEELKEMGLLRDKVPNPMRLPRCSRSGDIVEPMLIPQWYVNCKDMAKRAVEAVRNG 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 375 DIKFVPQQYENMYFSWMRDIQDWCISRQLWWGHRIPAW----------YDAEGNIYVGRSEADVRAE-----NNLPDDLE 439
Cdd:PTZ00419 423 ELKIIPSSHENVWYHWLENIQDWCISRQLWWGHRIPAYrviskgpetdPSDEEPWVVARSEEEALEKakkkfGLSEEDFE 502
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 440 LKQDDDVLDTWFSSGLWTFGTLGWPENTEELKTFHPTDVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVRDSQ 519
Cdd:PTZ00419 503 LEQDEDVLDTWFSSGLFPFSTLGWPDQTDDLQRFFPTSLLETGSDILFFWVARMVMMSLHLTDKLPFKTVFLHAMVRDSQ 582
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 520 GQKMSKSKGNVLDPIDLIDGIDLESLVAKRTAGMMQPHLRDKIEKQTRKEFPDGINAYGTDALRYTYYSLASTGRDIKFD 599
Cdd:PTZ00419 583 GEKMSKSKGNVIDPLEVIEGISLQDLNQKLYEGNLPEKEIKRAIELQKKEFPNGIPECGTDALRFGLLAYTQQGRNINLD 662
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 600 VGRIEGFRNFCNKIWNATNYVLMNCEDQD----CGADGSADYE-LSLADKWIISKLQETEIAVAEGVESYRLDLASQALY 674
Cdd:PTZ00419 663 INRVVGYRHFCNKLWNAVKFALMKLLKDFnlpnSTLFKPNNVEsLPWEDKWILHRLNVAIKEVTEGFKEYDFSEATQATY 742
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 675 DFVWNEYCAWYLELSKPVLwDDNASAAQKKGTRRTLIRVLEVILRLAHPLMPFITEEIWQKVKTLaGQSGDTIMHQPYPV 754
Cdd:PTZ00419 743 NFWLYELCDVYLELIKPRL-SKQSDGERKQHAQDVLHTVLDIGLRLLHPMMPFITEELYQRLPNY-LRKSESISIAKYPQ 820
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 755 ADTSKIDAAAIADLEWIKQAVVAVRNIRGEMNIAPGKAIPVLVVNANTDDLRRIEENRPFLTKLANLES---IAPLEGEA 831
Cdd:PTZ00419 821 PNPGWNNEALDEEMKIIMSIVKSIRSLIATLGIPNKTKPDCYVTAKDAELIELIESAENLISTLAKIGSvsvIPPIEEEA 900
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 832 PMSATALV----GKMELLVPMAGLIDTAAELARLDKEIEKLTKEVVKTEGKLNNPKFVDKAPTEVVDKERERLADFQASI 907
Cdd:PTZ00419 901 EVPKGCGFdvvdNKVIIYLNLDEFIDLKKELAKLEKKLAKLQKSLESYLKKISIPNYEDKVPEDVRKLNDEKIDELNEEI 980
|
970
....*....|...
gi 409026056 908 AKLTEQKAKMAAL 920
Cdd:PTZ00419 981 KQLEQAIEELKSL 993
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
1-918 |
0e+00 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 1034.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 1 MDKTYQPASIETQWYQTWEKNGYFK----PSGKgDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVG 76
Cdd:PRK14900 15 LAKGYEHREVEARWYPFWQERGYFHgdehDRTR-PPFSIVLPPPNVTGSLHLGHALTATLQDVLIRWKRMSGFNTLWLPG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 77 TDHAGIATQMVVER-LLDAEGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFI 155
Cdd:PRK14900 94 TDHAGIATQMIVEKeLKKTEKKSRHDLGREAFLERVWAWKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAVREVFV 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 156 QLYKDGLIYRGKRLVNWDPKLHTAVSDLEVISEEEK-GFLWHFRYPLADGSGHIVVATTRPETMLGDTAVAVHPEDERYQ 234
Cdd:PRK14900 174 RLHEEGLIYREKKLINWCPDCRTALSDLEVEHEEAHqGELWSFAYPLADGSGEIVVATTRPETMLGDTAVAVHPLDPRYM 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 235 QLVGKMIKLPLTDREIPIIAD-DYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNDDVpEKYRGMERFA 313
Cdd:PRK14900 254 ALHGKKVRHPITGRTFPIVADaILVDPKFGTGAVKVTPAHDFNDFEVGKRHGLEMITVIGPDGRMTAEA-GPLAGLDRFE 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 314 ARKQIVADFEALGLLEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEDGDIKFVPQQYENMYFSWMRD 393
Cdd:PRK14900 333 ARKEVKRLLAEQGLDRGAKPHVLPLGRCQRSATILEPLLSDQWYVRIEPLARPAIEAVEQGRTRFIPEQWTNTYMAWMRN 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 394 IQDWCISRQLWWGHRIPAWYDAEGNIYVGRSEAdvrAENNLPDDLELKQDDDVLDTWFSSGLWTFGTLGWPENTEELKTF 473
Cdd:PRK14900 413 IHDWCISRQLWWGHQIPAWYCPDGHVTVARETP---EACSTCGKAELRQDEDVLDTWFSSGLWPFSTMGWPEQTDTLRTF 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 474 HPTDVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDgidleslvakrtagm 553
Cdd:PRK14900 490 YPTSVMETGHDIIFFWVARMMMMGLHFMGEVPFRTVYLHPMVRDEKGQKMSKTKGNVIDPLVITE--------------- 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 554 mqphlrdkiekqtrkefpdginAYGTDALRYTYYSLASTGRDIKFDVGRIEGFRNFCNKIWNATNYVLMNCEDQDCGADG 633
Cdd:PRK14900 555 ----------------------QYGADALRFTLAALTAQGRDIKLAKERIEGYRAFANKLWNASRFALMNLSGYQERGED 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 634 SADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDDNASAaqKKGTRRTLIRV 713
Cdd:PRK14900 613 PARLARTPADRWILARLQRAVNETVEALEAFRFNDAANAVYAFVWHELCDWYIELAKEALASEDPEA--RRSVQAVLVHC 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 714 LEVILRLAHPLMPFITEEIWQKVKTLAGQSG--DTIMHQPYPVADtsKIDAAAIADLEWIKQAVVAVRNIRGEMNIAP-- 789
Cdd:PRK14900 691 LQTSYRLLHPFMPFITEELWHVLRAQVGASAwaDSVLAAEYPRKG--EADEAAEAAFRPVLGIIDAVRNIRGEMGIPWkv 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 790 --GKAIPVLV--VNANTDDLRRIEEnRPFLTKLANLESIAPLEGEA----PMSATALVGKMELLVPMAGLIDTAAELARL 861
Cdd:PRK14900 769 klGAQAPVEIavADPALRDLLQAGE-LARVHRVAGVEGSRLVVAAAtapaPQSAVGVGPGFEVRVPLAGVIDLAAETARV 847
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*..
gi 409026056 862 DKEIEKLTKEVVKTEGKLNNPKFVDKAPTEVVDKERERLADFQASIAKLTEQKAKMA 918
Cdd:PRK14900 848 DKEIGKVDQDLAVLERKLQNPSFVQNAPPAVVEKDRARAEELREKRGKLEAHRAMLS 904
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
3-920 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 866.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 3 KTYQPASiETQWYQTWEKNGYFKPSGK--GDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHA 80
Cdd:PLN02943 59 KSFDFTS-EERIYNWWESQGYFKPNFDrgGDPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIPGTDHA 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 81 GIATQMVVERLLDAEGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKD 160
Cdd:PLN02943 138 GIATQLVVEKMLASEGIKRTDLGRDEFTKRVWEWKEKYGGTITNQIKRLGASCDWSRERFTLDEQLSRAVVEAFVRLHEK 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 161 GLIYRGKRLVNWDPKLHTAVSDLEVISEEEKGFLWHFRYPLADGSG-HIVVATTRPETMLGDTAVAVHPEDERYQQLVGK 239
Cdd:PLN02943 218 GLIYQGSYMVNWSPNLQTAVSDLEVEYSEEPGTLYYIKYRVAGGSEdFLTIATTRPETLFGDVAIAVNPEDDRYSKYIGK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 240 MIKLPLT-DREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNDDVpekyrGMERFAARKQI 318
Cdd:PLN02943 298 MAIVPMTyGRHVPIIADRYVDKDFGTGVLKISPGHDHNDYLLARKLGLPILNVMNKDGTLNEVA-----GLYWFEAREKL 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 319 VADFEALGLLEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEDGDIKFVPQQYENMYFSWMRDIQDWC 398
Cdd:PLN02943 373 WSDLEETGLAVKKEPHTLRVPRSQRGGEVIEPLVSKQWFVTMEPLAEKALKAVENGELTIIPERFEKIYNHWLSNIKDWC 452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 399 ISRQLWWGHRIPAWY----DAEGNIYVGRSEADV--RAENNLPDDLELKQDDDVLDTWFSSGLWTFGTLGWPE-NTEELK 471
Cdd:PLN02943 453 ISRQLWWGHRIPVWYivgkDCEEDYIVARSAEEAleKAREKYGKDVEIYQDPDVLDTWFSSALWPFSTLGWPDvSAEDFK 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 472 TFHPTDVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIdgidleslvakrta 551
Cdd:PLN02943 533 KFYPTTVLETGHDILFFWVARMVMMGIEFTGTVPFSYVYLHGLIRDSQGRKMSKTLGNVIDPLDTI-------------- 598
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 552 gmmqphlrdkiekqtrKEfpdginaYGTDALRYTyYSLASTGRDIKFDVGRIEGFRNFCNKIWNATNYVLMNCEDQ---- 627
Cdd:PLN02943 599 ----------------KE-------FGTDALRFT-LALGTAGQDLNLSTERLTSNKAFTNKLWNAGKFVLQNLPSQsdts 654
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 628 ------DCGADGSADY-ELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDDNASA 700
Cdd:PLN02943 655 awehilACKFDKEESLlSLPLPECWVVSKLHELIDSVTTSYDKYFFGDVGREIYDFFWSDFADWYIEASKTRLYHSGDNS 734
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 701 AQKKgTRRTLIRVLEVILRLAHPLMPFITEEIWQKVKtlagQSGDTIMHQPYPVADTSKiDAAAIADLEWIKQAVVAVRN 780
Cdd:PLN02943 735 ALSR-AQAVLLYVFENILKLLHPFMPFVTEELWQALP----YRKEALIVSPWPQTSLPK-DLKSIKRFENLQSLTRAIRN 808
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 781 IRGEMNIAPGKAIPVLVVnANTDDLRRIEENRPFLTKLANLE-------SIAPleGEAPMSATALVGK-MELLVPMAGLI 852
Cdd:PLN02943 809 ARAEYSVEPAKRISASIV-ASAEVIEYISKEKEVLALLSRLDlqnvhftDSPP--GDANQSVHLVASEgLEAYLPLADMV 885
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 409026056 853 DTAAELARLDKEIEKLTKEVVKTEGKLNNPKFVDKAPTEVVDKERERLADFQASIaKLTeqKAKMAAL 920
Cdd:PLN02943 886 DISAEVERLSKRLSKMQTEYDALAARLSSPKFVEKAPEDVVRGVREKAAEAEEKI-KLT--KNRLAFL 950
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
1-919 |
0e+00 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 823.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 1 MDKTYQPASIETQWYQTWEKNGYFKPSGKGD--PYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTD 78
Cdd:PLN02381 96 MAKQYSPSAVEKSWYAWWEKSGYFGADAKSSkpPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRMSGYNALWVPGVD 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 79 HAGIATQMVVER-LLDAEGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQL 157
Cdd:PLN02381 176 HAGIATQVVVEKkLMRERHLTRHDIGREEFVSEVWKWKDEYGGTILNQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRL 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 158 YKDGLIYRGKRLVNWDPKLHTAVSDLEV----ISEE------------EKGFLWHFRYPLADGSGHIVVATTRPETMLGD 221
Cdd:PLN02381 256 YKEGLIYRDIRLVNWDCTLRTAISDVEVdyidIKERtllkvpgydkpvEFGVLTSFAYPLEGGLGEIVVATTRIETMLGD 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 222 TAVAVHPEDERYQQLVGKMIKLPLTDREIPIIAD-DYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLND 300
Cdd:PLN02381 336 TAIAIHPDDERYKHLHGKFAVHPFNGRKLPIICDaILVDPNFGTGAVKITPAHDPNDFEVGKRHNLEFINIFTDDGKINS 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 301 DVPEKYRGMERFAARKQIVADFEALGLLEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEDGDIK--- 377
Cdd:PLN02381 416 NGGSEFAGMPRFAAREAVIEALQKKGLYRGAKNNEMRLGLCSRTNDVVEPMIKPQWFVNCSSMAKQALDAAIDGENKkle 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 378 FVPQQYENMYFSWMRDIQDWCISRQLWWGHRIPAWY-----DAEGNI-------YVGRSEADVRAENNLP---DDLELKQ 442
Cdd:PLN02381 496 FIPKQYLAEWKRWLENIRDWCISRQLWWGHRIPAWYvtledDQLKELgsyndhwVVARNESDALLEASQKfpgKKFELSQ 575
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 443 DDDVLDTWFSSGLWTFGTLGWPENTEELKTFHPTDVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVRDSQGQK 522
Cdd:PLN02381 576 DPDVLDTWFSSGLFPLSVLGWPDDTDDLKAFYPTSVLETGHDILFFWVARMVMMGMQLGGDVPFRKVYLHPMIRDAHGRK 655
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 523 MSKSKGNVLDPIDLIDGIDLESLVAKRTAGMMQPHLRDKIEKQTRKEFPDGINAYGTDALRYTYYSLASTGRDIKFDVGR 602
Cdd:PLN02381 656 MSKSLGNVIDPLEVINGISLEGLHKRLEEGNLDPKELVVAKEGQKKDFPNGIAECGTDALRFALVSYTAQSDKINLDILR 735
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 603 IEGFRNFCNKIWNATNYVLMNcedqdCGADGSADYELSLAD-----KWIISKLQETEIAVAEGVESYRLDLASQALYDFV 677
Cdd:PLN02381 736 VVGYRQWCNKLWNAVRFAMSK-----LGDDYTPPATLSVETmpfscKWILSVLNKAISKTVSSLDAYEFSDAASTVYSWW 810
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 678 WNEYCAWYLELSKPVLWDDNAS-AAQKKGTRRTLIRVLEVILRLAHPLMPFITEEIWQKVKTLAGQS-GDTIMHQPYPVA 755
Cdd:PLN02381 811 QYQFCDVFIEAIKPYFAGDNPEfASERAAAQDTLWICLDTGLRLLHPFMPFVTEELWQRLPQPKDHTrKDSIMISEYPSA 890
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 756 DTSKIDAAAIADLEWIKQAVVAVRNIRGE-MNIAPGKAIPVLVVNANTDDLRRIEENRPFLTKLANLESIAPLEGE---- 830
Cdd:PLN02381 891 VEAWTNEKVEYEMDLVLSTVKCLRSLRAEvLEKQKNERLPAFALCRNQEIAAIIKSHQLEILTLANLSSLKVLLSEndap 970
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 831 APMSATALVGK-MELLVPMAGLIDTAAELARLDKEIEKLTKEVVKTEGKLNNPKFVDKAPTEVVDKERERLADFQASIAK 909
Cdd:PLN02381 971 PAGCAFENVNEnLKVYLQAQGAVNAEAELEKLRNKMDEIQKQQEKLEKKMNASGYKEKVPANIQEEDARKLTKLLQELEF 1050
|
970
....*....|
gi 409026056 910 LTEQKAKMAA 919
Cdd:PLN02381 1051 FEKESKRLEA 1060
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
13-599 |
0e+00 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 761.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 13 QWYQTWEKNGYFKPSGKGD----PYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGIATQMVV 88
Cdd:pfam00133 1 QIYEFWDEQGYFKPELEKRkgkpSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTEQVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 89 ERLLDA-EGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLIYRGK 167
Cdd:pfam00133 81 EKKLGIkEKKTRHKYGREEFREKCREWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIYRGK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 168 RLVNWDPKLHTAVSDLEVISEEEKGFLWHFRYPLADGSG-HIVVATTRPETMLGDTAVAVHPE----------------- 229
Cdd:pfam00133 161 KLVNWSPALNTALSNLEVEYKDVKGPSIHVAFPLADDEGaSLVIWTTTPWTLPGNTAVAVNPEfdyvitgegyilaeall 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 230 --------------DERYQQLVGKMIKLPLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDD 295
Cdd:pfam00133 241 kslykkgtdkkileDFRGKELEGKEAIHPFVNREIPIITDDYVDMEFGTGAVHIAPAHGENDYEVGQRHNLEVINPVDDD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 296 ADLNDDVPEkYRGMERFAARKQIVADFEALGLLEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEdgD 375
Cdd:pfam00133 321 GTFTEEAPD-FQGVYRFDARKKIVELLTEKGLLLKIEPFTHSYPFCWRSGTPIIPRATPQWFVRMDELADQALEAVE--K 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 376 IKFVPQQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDAE-GNIYV---------GRSEADVRAENNLPD--------D 437
Cdd:pfam00133 398 VQFVPKSGEKRYFNWLANIQDWCISRQRWWGHPIPAWVSKDtEEVVCrgelfelvaGRFEEEGSIKWLHREakdklgygK 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 438 LELKQDDDVLDTWFSSGLWTFGTLGWPE-NTEELKTFHPTDVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVR 516
Cdd:pfam00133 478 GTLEQDEDVLDTWFSSGSWPFSTLGWPFvNTEEFKKFFPADMLLEGSDQTRGWFYRMIMLSTALTGSVPFKNVLVHGLVR 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 517 DSQGQKMSKSKGNVLDPIDLIDgidleslvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRYtYYSLASTGRDI 596
Cdd:pfam00133 558 DEQGRKMSKSLGNVIDPLDVID-------------------------------------KYGADALRL-WLANSDYGRDI 599
|
...
gi 409026056 597 KFD 599
Cdd:pfam00133 600 NLS 602
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
31-598 |
0e+00 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 578.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 31 DPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGIATQMVVERLLDAEGVSRHDLGREKFLEK 110
Cdd:cd00817 1 PVFVIDTPPPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQVVVEKKLGIEGKTRHDLGREEFLEK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 111 VWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLIYRGKRLVNWDPKLHTAVSDLEViseee 190
Cdd:cd00817 81 CWEWKEESGGKIREQLKRLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLIYRDNRLVNWCPKLRTAISDIEV----- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 191 kgflwhfrypladgsghivvattrpetmlgdtavavhpederyqqlvgkmiklpltdreipiiaddyvdkdfgtgcvkit 270
Cdd:cd00817 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 271 pahdfndyemgkrhnlpiiniltddadlnddvpekyrgmerfaarkqivadfealgllekiddhvlkvprGDRTGVVIEP 350
Cdd:cd00817 156 ----------------------------------------------------------------------CSRSGDVIEP 165
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 351 YLTDQWYVKTAPLAEQAIKAVEDGDIKFVPQQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDAEGN-IYVGRSEADVR 429
Cdd:cd00817 166 LLKPQWFVKVKDLAKKALEAVKEGDIKFVPERMEKRYENWLENIRDWCISRQLWWGHRIPAWYCKDGGhWVVAREEDEAI 245
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 430 -----AENNLPDDLELKQDDDVLDTWFSSGLWTFGTLGWPENTEELKTFHPTDVLVTGFDIIFFWVARMIMLTLHFRKEI 504
Cdd:cd00817 246 dkaapEACVPCGGEELKQDEDVLDTWFSSSLWPFSTLGWPEETKDLKKFYPTSLLVTGHDIIFFWVARMIMRGLKLTGKL 325
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 505 PFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDGidleslvakrtagmmqphlrdkiekqtrkefpdginaYGTDALRY 584
Cdd:cd00817 326 PFKEVYLHGLVRDEDGRKMSKSLGNVIDPLDVIDG-------------------------------------YGADALRF 368
|
570
....*....|....
gi 409026056 585 TYYSLASTGRDIKF 598
Cdd:cd00817 369 TLASAATQGRDINL 382
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
1-839 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 571.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 1 MDKTYQPASIETQWYQTWEKNGY--FKPSGKGDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTD 78
Cdd:PRK13208 6 LPKKYDPEELEEKWQKIWEEEGTykFDPDERKPVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVFFPQGWD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 79 HAGIATQMVVERLLdaeGVSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLY 158
Cdd:PRK13208 86 DNGLPTERKVEKYY---GIRKDDISREEFIELCRELTDEDEKKFRELWRRLGLSVDWSLEYQTISPEYRRISQKSFLDLY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 159 KDGLIYRGKRLVNWDPKLHTAVSDLEVISEEEKGFLWHFRYPLADGsGHIVVATTRPETMLGDTAVAVHPEDERYQQLVG 238
Cdd:PRK13208 163 KKGLIYRAEAPVLWCPRCETAIAQAEVEYREREGKLNYIKFPVEDG-EEIEIATTRPELLPACVAVVVHPDDERYKHLVG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 239 KMIKLPLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNdDVPEKYRGMERFAARKQI 318
Cdd:PRK13208 242 KTAIVPLFGVEVPILADPLVDPDFGTGAVMICTFGDKTDVTWWRELNLPTRIIIDEDGRMT-EAAGKLAGLTIEEARKKI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 319 VADFEALGLLEKIDDHVLKVP---RGDRTgvvIEPYLTDQWYVKTAPLAEQAIKAVEdgDIKFVPQQYENMYFSWMRDIQ 395
Cdd:PRK13208 321 VEDLKSGGLLGKQEPIKHNVKfceRCDTP---LEILVTRQWFIKVLDLKEELLERGK--EINWYPEHMRVRLENWIEGLN 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 396 -DWCISRQLWWGHRIPAWY--DAEGNIYVGRSEADVRAENNLP--------DDLELKQDDDVLDTWFSSGL-WTFGTlGW 463
Cdd:PRK13208 396 wDWCISRQRYFGTPIPVWYckDCGHPILPDEEDLPVDPTKDEPpgykcpqcGSPGFEGETDVMDTWATSSItPLIVT-GW 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 464 PENTEELKTFHPTDVLVTGFDIIFFW----VARMIMLTlhfrKEIPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLidg 539
Cdd:PRK13208 475 ERDEDLFEKVFPMDLRPQGHDIIRTWlfytILRAYLLT----GKLPWKNIMISGMVLDPDGKKMSKSKGNVVTPEEL--- 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 540 idleslvakrtagmmqphlrdkIEKqtrkefpdginaYGTDALRYtYYSLASTGRDIKFDVGRIEGFRNFCNKIWNATNY 619
Cdd:PRK13208 548 ----------------------LEK------------YGADAVRY-WAASARLGSDTPFDEKQVKIGRRLLTKLWNASRF 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 620 VLMncedQDCGADGSADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDDNAS 699
Cdd:PRK13208 593 VLH----FSADPEPDKAEVLEPLDRWILAKLAKVVEKATEALENYDFAKALEEIESFFWHVFCDDYLELVKSRAYGEDEE 668
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 700 AAQkKGTRRTLIRVLEVILRLAHPLMPFITEEIWQKVKtlagqsGDTIMHQPYPVADTSKIDAAAIADLEWIKQAVVAVR 779
Cdd:PRK13208 669 EEQ-KSARYTLYTVLDTLLRLLAPFLPFITEEVWSWLY------GGSVHRASWPEPDEELIDEEDEELGELAKEILSAVR 741
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 780 NIRGEMNIAPGKAIPVLVVNANtDDLRRIEENRPFLTKLANLESIAPLEGEAPMSATALV 839
Cdd:PRK13208 742 KYKSEAGLSLNAPLKKVEVYGP-ADLELLEAAEEDLKAAGNIEELELVEGDPELEVEIIA 800
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
7-838 |
5.54e-113 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 368.64 E-value: 5.54e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 7 PASIETQWYQTWEKNGYFKPS---GKGDPYCIMIP-PPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTD-HaG 81
Cdd:COG0060 18 LPKREPEILKFWEENDIYEKSreaRAGRPKFVLHDgPPYANGDIHIGHALNKILKDIIVRYKTMRGFDVPYVPGWDcH-G 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 82 --IATQmvVERLLDAEGVSRHDLGREKFLEK----VWQWKEEsggtITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFI 155
Cdd:COG0060 97 lpIELK--VEKELGIKKKDIEKVGIAEFREKcreyALKYVDE----QREDFKRLGVWGDWDNPYLTMDPEYEESIWWALK 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 156 QLYKDGLIYRGKRLVNWDPKLHTAVSDLEVISEEEK------GFlwhfryPLADGSG-------HIVVATTRPETMLGDT 222
Cdd:COG0060 171 KLYEKGLLYKGLKPVPWCPRCGTALAEAEVEYKDVTspsiyvKF------PVKDEKAlllledaYLVIWTTTPWTLPANL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 223 AVAVHPE----------DERY---------------------------QQLVGK-----MIKLPLTDREIPIIADDYVDK 260
Cdd:COG0060 245 AVAVHPDidyvlvevtgGERLilaealveavlkelgiedyevlatfkgAELEGLryehpFYYVVGYDRAHPVILGDYVTT 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 261 DFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNDDVPEkYRGMERFAARKQIVADFEALGLLEKIDDHVLKVPR 340
Cdd:COG0060 325 EDGTGIVHTAPGHGEDDFEVGKKYGLPVLNPVDDDGRFTEEAPL-FAGLFVKDANPAIIEDLKERGALLAREKITHSYPH 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 341 GDRTGvviEP---YLTDQWYVKTAPLAEQAIKAVEDgdIKFVPQQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDAEG 417
Cdd:COG0060 404 CWRCK---TPliyRATPQWFISMDKLRDRALEAIEK--VNWIPEWGEGRFGNMLENRPDWCISRQRYWGVPIPIWVCEDC 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 418 N------IYVGRSEADVRAENN------------LPDDL-------ELKQDDDVLDTWFSSGLWTFGTLgwpENTEELKt 472
Cdd:COG0060 479 GelhrteEVIGSVAELLEEEGAdawfeldlhrpfLDETLkcpkcggTMRRVPDVLDVWFDSGSMHFAVL---ENREELH- 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 473 fHPTDVLVTGFDII---FFwvarmimlTLH-----FRKEIPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDgidles 544
Cdd:COG0060 555 -FPADFYLEGSDQTrgwFY--------SSLltstaLFGRAPYKNVLTHGFVLDEDGRKMSKSLGNVVDPQEVID------ 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 545 lvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRYtYYSLASTGRDIKFDVGRIEGFRNFCNKIWNATNYVLMNC 624
Cdd:COG0060 620 -------------------------------KYGADILRL-WVASSDYWGDLRFSDEILKEVRDVYRRLRNTYRFLLANL 667
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 625 EDQDCGADGSADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDDNASAAQKK 704
Cdd:COG0060 668 DDFDPAEDAVPYEDLPELDRWILSRLNELIKEVTEAYDNYDFHRAYRALHNFCVEDLSNWYLDISKDRLYTEAADSLDRR 747
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 705 GTRRTLIRVLEVILRLAHPLMPFITEEIWQkvkTLAGQSGDTIMHQPYPVADTSKIDAAAIADLEWIKQAVVAVR----N 780
Cdd:COG0060 748 AAQTTLYEVLETLVRLLAPILPFTAEEIWQ---NLPGEAEESVHLADWPEVDEELIDEELEAKWDLVREVRSAVLkaleA 824
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*....
gi 409026056 781 IRGEMNI-APGKAIPVLVVNAntDDLRRIEENRPFLTKLANLESIAPLEGEAPMSATAL 838
Cdd:COG0060 825 ARKEKLIrQPLEAAVVLYADE--ELAAALESLGDLLAEELNVSEVELVDDAEDLGKDAL 881
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
32-598 |
2.97e-75 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 248.87 E-value: 2.97e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 32 PYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGIATQMVVERLLDAEGVSRHdlgREKFLEKV 111
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAERKGGRKKKTIW---IEEFREDP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 112 WQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLIYRGKRLVnwdpklhtavsdleviseeek 191
Cdd:cd00668 78 KEFVEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYRGTHPV--------------------- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 192 gflwhfrypladgsghivvattrpetmlgdtavavhpederyqqlvgkmiklpltdreipiiaddyvdkdfgtgcvkitp 271
Cdd:cd00668 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 272 ahdfndyemgkrhnlpiiniltddadlnddvpekyrgmerfaarkqivadfealgllekiddhvlkvprgdrtgvviepY 351
Cdd:cd00668 137 -------------------------------------------------------------------------------R 137
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 352 LTDQWYVKTAPLAEQAIKAVEDGdiKFVPQQYENMYFSWMRDIQDWCISRQLWWGHRIPAWydaegniyvgrseadvrae 431
Cdd:cd00668 138 ITEQWFFDMPKFKEKLLKALRRG--KIVPEHVKNRMEAWLESLLDWAISRQRYWGTPLPED------------------- 196
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 432 nnlpddlelkqdddVLDTWFSSGLWTFGTLGWPENTEELKTFHPTDVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYV 511
Cdd:cd00668 197 --------------VFDVWFDSGIGPLGSLGYPEEKEWFKDSYPADWHLIGKDILRGWANFWITMLVALFGEIPPKNLLV 262
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 512 HGLVRDSQGQKMSKSKGNVLDPIDLidgidleslvakrtagmmqphlrdkiekqtrkefpdgINAYGTDALRYTYYSLAS 591
Cdd:cd00668 263 HGFVLDEGGQKMSKSKGNVIDPSDV-------------------------------------VEKYGADALRYYLTSLAP 305
|
....*..
gi 409026056 592 TGRDIKF 598
Cdd:cd00668 306 YGDDIRL 312
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
598-735 |
2.92e-61 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 203.94 E-value: 2.92e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 598 FDVGRIEGFRNFCNKIWNATNYVLMNCEDQDCGADGSAdyELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFV 677
Cdd:cd07962 1 FDEKRVEGGRNFCNKLWNAARFVLMNLEDDDEPEEDPE--SLSLADRWILSRLNKTVEEVTEALENYRFSEAATALYEFF 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 409026056 678 WNEYCAWYLELSKPVLWDDnaSAAQKKGTRRTLIRVLEVILRLAHPLMPFITEEIWQK 735
Cdd:cd07962 79 WNDFCDWYLELVKPRLYGE--DEEEKKAARATLYYVLETILRLLHPFMPFITEELWQR 134
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
11-734 |
8.73e-61 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 223.88 E-value: 8.73e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 11 ETQWYQTWEKNGYFK---PSGKGDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGIATQMV 87
Cdd:PLN02843 9 EPEIQKLWEENQVYKrvsDRNNGESFTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWDCHGLPIELK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 88 VERLLDAEgvSRHDLGREKFLEKVWQWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLIYRGK 167
Cdd:PLN02843 89 VLQSLDQE--ARKELTPIKLRAKAAKFAKKTVDTQRESFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLNGYIYRGR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 168 RLVNWDPKLHTAVSDLE-----------------VISEEEKGFLWHfRYPLADGSghIVVATTRPETMLGDTAVAVHP-- 228
Cdd:PLN02843 167 KPVHWSPSSRTALAEAEleypeghvsksiyvafpVVSPSETSPEEL-EEFLPGLS--LAIWTTTPWTMPANAAVAVNDkl 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 229 -----------EDERY-----------------------------------------------QQLVGKMIKLPLTDREI 250
Cdd:PLN02843 244 qysvvevqsfsEDESTsggnkkkrpgnvlkeqqklflivatdlvpaleakwgvklvvlktfpgSDLEGCRYIHPLYNRES 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 251 PIIAD-DYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNDDVPEkYRGMERFAA-RKQIVADFEALGLL 328
Cdd:PLN02843 324 PVVIGgDYITTESGTGLVHTAPGHGQEDYITGLKYGLPLLSPVDDAGKFTEEAGQ-FSGLSVLGEgNAAVVEALDEAGSL 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 329 EKIDDHVLKVPRGDRTGvviEPYL---TDQWYVKTAPLAEQAIKAVEdgDIKFVPQQYENMYFSWMRDIQDWCISRQLWW 405
Cdd:PLN02843 403 LMEEAYGHKYPYDWRTK---KPTIfraTEQWFASVEGFRQAALDAID--KVKWIPAQGENRIRAMVSGRSDWCISRQRTW 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 406 GHRIPAWYDAEGNIYVGRSE--ADVRA---------------ENNLPDDLELKQDD-----DVLDTWFSSGLWTFGTLGw 463
Cdd:PLN02843 478 GVPIPVFYHVETKEPLMNEEtiAHVKSivaqkgsdawwymdvEDLLPEKYRDKASDyekgtDTMDVWFDSGSSWAGVLG- 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 464 peNTEELKtfHPTDVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDGidle 543
Cdd:PLN02843 557 --SREGLS--YPADLYLEGSDQHRGWFQSSLLTSVATKGKAPYKSVLTHGFVLDEKGFKMSKSLGNVVDPRLVIEG---- 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 544 slvakrtagmmqphlrdkieKQTRKEFPdginAYGTDALRYTYYSLASTGrDIKFDVGRIEGFRNFCNKIWNATNYVLMN 623
Cdd:PLN02843 629 --------------------GKNQKQEP----AYGADVLRLWVASVDYTG-DVLIGPQILKQMSDIYRKLRGTLRYLLGN 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 624 CEDQDcgADGSADYE-LSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDDNASAAQ 702
Cdd:PLN02843 684 LHDWK--PDNAVPYEdLPSIDKYALFQLENVVNEIEESYDNYQFFKIFQILQRFTIVDLSNFYLDVAKDRLYVGGTTSFT 761
|
810 820 830
....*....|....*....|....*....|..
gi 409026056 703 KKGTRRTLIRVLEVILRLAHPLMPFITEEIWQ 734
Cdd:PLN02843 762 RRSCQTVLAAHLLSLLRAIAPILPHLAEDAWQ 793
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
1-790 |
4.37e-57 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 211.45 E-value: 4.37e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 1 MDKTYQPASIETQWYQTWEKNGYFK---PSGKGDPYC-IMIPPPnvTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVG 76
Cdd:COG0495 1 MQERYNPKEIEKKWQKYWEENGTFKadeDSSKPKYYVlDMFPYP--SGRLHMGHVRNYTIGDVVARYKRMQGYNVLHPMG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 77 TD-------HAGIATqmvverlldaeGVSRHDlgrekflekvwqWKEESGGTITRQLRRLGASPDWSRERFTMDDGFYKA 149
Cdd:COG0495 79 WDafglpaeNAAIKN-----------GVHPAE------------WTYENIANMRRQLKRLGLSYDWSREIATCDPEYYKW 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 150 VQEVFIQLYKDGLIYRGKRLVNWDPKLHTAVSDLEVI---SE------EEKG----FL---------------------- 194
Cdd:COG0495 136 TQWIFLQLYEKGLAYRKEAPVNWCPVDQTVLANEQVIdgrCWrcgapvEKKElpqwFLkitdyadellddldkldgwpek 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 195 -------W-------HFRYPLADGSGHIVVATTRPETMLGDTAVAV---HP------------EDERYQQLVGKMIKL-- 243
Cdd:COG0495 216 vktmqrnWigrsegaEVDFPVEGSDEKITVFTTRPDTLFGATFMVLapeHPlvkelatpeqnaAVAAFIEEAKKKSEIer 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 244 ------------------PLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIIN-ILTDDADLNDDVPE 304
Cdd:COG0495 296 tsetkektgvftglyainPLTGEKIPIWIADYVLMDYGTGAVMAVPAHDQRDFEFAKKYGLPIKQvIAPEDGDDPDILEE 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 305 ------------KYRGMERFAARKQIVADFEALGLLEKiddhvlKVprgdrtgvviepyltdqwyvktaplaeqaikave 372
Cdd:COG0495 376 aytgdgvlinsgEFDGLDSEEAKEAIIEWLEEKGLGKR------KV---------------------------------- 415
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 373 dgdikfvpqQYenmyfswmRdIQDWCISRQLWWGHRIPAWYDAEGNIyVGRSEAD--VRaennLPDDLE--------LKQ 442
Cdd:COG0495 416 ---------NY--------R-LRDWLISRQRYWGEPIPIIHCEDCGV-VPVPEDQlpVE----LPEDVDfdptggspLAR 472
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 443 DD------------------DVLDTWF-SSglwtfgtlgW-------PENTEElktfhPTDVlvtgfDIIFFWvarM--- 493
Cdd:COG0495 473 APewvnvtcpkcggparretDTMDTFVdSS---------WyylrytdPHNDEA-----PFDP-----EAANYW---Lpvd 530
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 494 ---------IMLTLHFR--------------KEiPFHTVYVHGLVRD--------SQGQKMSKSKGNVLDPIDLIDgidl 542
Cdd:COG0495 531 qyiggiehaILHLLYARfftkvlrdlglvsfDE-PFKRLLTQGMVLEvgkdgvviGGIEKMSKSKGNVVDPDEIIE---- 605
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 543 eslvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRyTYysLASTG---RDIKF-DVGrIEGFRNFCNKIWNatn 618
Cdd:COG0495 606 ---------------------------------KYGADTLR-LF--EMFAGppeRDLEWsDSG-VEGAYRFLNRVWR--- 645
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 619 yvLMNCEDQDCGADGSadyELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVwNeycawylELSKPVLWDDNA 698
Cdd:COG0495 646 --LVVDEAEALKLDVA---DLSEADKELRRALHKTIKKVTEDIERLRFNTAIAALMELV-N-------ALYKAKDSGEAD 712
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 699 SAAQKKGtrrtlirvLEVILRLAHPLMPFITEEIWQKVktlaGQSGDtIMHQPYPVADtskiDAAAIADlewIKQAVVAV 778
Cdd:COG0495 713 RAVLREA--------LETLVLLLAPFAPHIAEELWERL----GHEGS-VADAPWPEAD----EAALVED---EVTIVVQV 772
|
970
....*....|....
gi 409026056 779 rN--IRGEMNIAPG 790
Cdd:COG0495 773 -NgkVRGKIEVPAD 785
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
46-909 |
4.57e-50 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 191.23 E-value: 4.57e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 46 LHMGHGFQESIMDALIRYNRMKGKNTL----WQV-GTDHAGIATQM------VVERLLDAEGVSRHDLgrEKF---LEKV 111
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLfpmaFHVtGTPILGIAERIargdpeTIELYKSLYGIPEEEL--EKFkdpEYIV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 112 WQWKEEsggtITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLIYRGKRLVNWDPKLHTAVSDLEVISEEEK 191
Cdd:PRK12300 79 EYFSEE----AKEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPVGDHDLLDGEEP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 192 GFL-WHFRYPLADGSGHIVVATTRPETMLGDTAVAVHPEDE---------------------RYQ-------------QL 236
Cdd:PRK12300 155 EIVeYTLIKFEESEDLILPAATLRPETIFGVTNLWVNPDATyvkaevdgekwivskeaaeklSFQdrdveiieeikgsEL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 237 VGKMIKLPLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDY----EMGKRHNL-------PIINI-------------- 291
Cdd:PRK12300 235 IGKKVKNPVTGKEVPILPADFVDPDNGTGVVMSVPAHAPYDYvalrDLKKNKELldviepiPLIEVegygefpakevvek 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 292 --LTDDAD-------------------LNDDVPEkYRGMERFAARKQIVADFEALGLLEKI----DDHVlkVPR-GDRTG 345
Cdd:PRK12300 315 lgIKSQEDpeleeatkevyraefhkgvLKENTGE-YAGKPVREAREKITKDLIEKGIADIMyefsNRPV--YCRcGTECV 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 346 VVIepyLTDQWYVK-TAP-LAEQAIKAVEdgDIKFVPQQY-ENM--YFSWMRdiqDWCISRQLWWGHRIPaWyDAEgniY 420
Cdd:PRK12300 392 VKV---VKDQWFIDySDPeWKELAHKALD--NMEIIPEEYrKEFenTIDWLK---DRACARRRGLGTRLP-W-DEE---W 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 421 VGRSEAD-------------VRAENNLPDDLelkqDDDVLDTWF---------SSGlwtfgtLGWPENT-----EELKTF 473
Cdd:PRK12300 459 IIESLSDstiymayytiahkIREYGIKPEQL----TPEFFDYVFlgkgdpeevSKK------TGIPKEIleemrEEFLYW 528
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 474 HPTDVLVTGFDII-----FFwvarmIMltlH----FRKEIPFHTVYVHGLVRdSQGQKMSKSKGNVLDpidlidgidles 544
Cdd:PRK12300 529 YPVDWRHSGKDLIpnhltFF-----IF---NhvaiFPEEKWPRGIVVNGFVL-LEGKKMSKSKGNVIP------------ 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 545 lvakrtagmmqphLRDKIEKqtrkefpdginaYGTDALRYTYYSLASTGRDIKFD-------VGRIEGFRNFCNKIwnat 617
Cdd:PRK12300 588 -------------LRKAIEE------------YGADVVRLYLTSSAELLQDADWRekevesvRRQLERFYELAKEL---- 638
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 618 nyvlmncedqdcgADGSADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQ-ALYDFVwnEYCAWYLELSkpvlwdd 696
Cdd:PRK12300 639 -------------IEIGGEEELRFIDKWLLSRLNRIIKETTEAMESFQTRDAVQeAFYELL--NDLRWYLRRV------- 696
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 697 nasaaqKKGTRRTLIRVLEVILRLAHPLMPFITEEIWQKVktlaGQSGdTIMHQPYPVADTSKIDAAAIADLEWIKQAVV 776
Cdd:PRK12300 697 ------GEANNKVLREVLEIWIRLLAPFTPHLAEELWHKL----GGEG-FVSLEKWPEPDESKIDEEAELAEEYVKRLIE 765
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 777 AVRNIRGEMNIAPGKAIPVLVVNANTDDLRRIEENRPFltklanlesiapleGEApmsatalvgkmellvpMAGLIDtAA 856
Cdd:PRK12300 766 DIREILKVAKIKPKKVYIYVAPDWKYEVLEIAAENGDV--------------KEA----------------IKELMK-DE 814
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|...
gi 409026056 857 ELARLDKEIEKLTKEVVKTEGKLnnPKFVDKAPTEVVDkERERLADFQASIAK 909
Cdd:PRK12300 815 ELRKHGKEVAKLAQKIVKEVLKL--DKEVRKLILKNID-EEEVLEEAKDFLEK 864
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
643-797 |
1.69e-42 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 151.40 E-value: 1.69e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 643 DKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKPVLWDDNASAAqkkgTRRTLIRVLEVILRLAH 722
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLSDWYLELIKDRLYGEEPDSR----AQTTLYEVLETLLRLLA 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 409026056 723 PLMPFITEEIWQKvktlagqsgDTIMHQPYPVaDTSKIDAAAIADLEWIKQAVVAVRNIRGEMNIAPGKAIPVLV 797
Cdd:pfam08264 77 PFMPFITEELWQK---------ESIHLAPWPE-DAELEEAELEEAFELRQEIVQAIRKLRSELKIKKSLPLEVVI 141
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
5-758 |
2.02e-42 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 167.69 E-value: 2.02e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 5 YQPASIETQWYQTWEKNGYFKP-----SGKGDPYCI-MIPPPNVTGsLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTD 78
Cdd:PLN02563 80 YPFHEIEPKWQRYWEENRTFRTpddvdTSKPKFYVLdMFPYPSGAG-LHVGHPEGYTATDILARYKRMQGYNVLHPMGWD 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 79 HAGI-ATQMVVERLLDAEGVSRHDLGREKflekvwqwkeesggtitRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQL 157
Cdd:PLN02563 159 AFGLpAEQYAIETGTHPKITTLKNIARFR-----------------SQLKSLGFSYDWDREISTTEPEYYKWTQWIFLQL 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 158 YKDGLIYRGKRLVNWDPKLHTAVSDLEVIS------------------------------EEEKGFLW------------ 195
Cdd:PLN02563 222 LKRGLAYQAEVPVNWCPALGTVLANEEVVDglsergghpvirkpmrqwmlkitayadrllEDLDDLDWpesikemqrnwi 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 196 ------HFRYPLADGSG-----HIVVATTRPETMLGDTAVAVHPEDERYQQLV--------------------------- 237
Cdd:PLN02563 302 grsegaELDFSVLDGEGkerdeKITVYTTRPDTLFGATYLVVAPEHPLLSSLTtaeqkeaveeyvdaasrksdlertelq 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 238 --------GKMIKLPLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIINILTDDADLNDDVPEKYRGM 309
Cdd:PLN02563 382 kektgvftGSYAINPATGEAIPIWVADYVLGSYGTGAIMAVPAHDTRDFEFAQKFDLPIKWVVKPADGNEDDAEKAYTGE 461
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 310 ERFAARKQIVADFEalGLLEKiddhvlkvprgDRTGVVIEpyltdqWyvktaplAEQAIKAVEDGDIKfvpqqyenmyfs 389
Cdd:PLN02563 462 GVIVNSSSSGLDIN--GLSSK-----------EAAKKVIE------W-------LEETGNGKKKVNYK------------ 503
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 390 wmrdIQDWCISRQLWWGHRIPAWYDAEGNIYVGRSEADvraennLPddLELKQDDDVLDT------------WF-----S 452
Cdd:PLN02563 504 ----LRDWLFARQRYWGEPIPVVFLEDSGEPVPVPESD------LP--LTLPELDDFTPTgtgepplakavsWVntvdpS 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 453 SGLW----TFGTLGW------------PENTEEL------KTFHPTDVLVTG-----FDIIF--FW--VARMIMLTLHfr 501
Cdd:PLN02563 572 SGKParreTNTMPQWagscwyylrfmdPKNSNALvdkekeKYWMPVDLYVGGaehavLHLLYarFWhkVLYDIGVVST-- 649
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 502 KEiPFHTVYVHGLV---------RDSQGQKMSKSKGNVLDPIDliDGIDLESLVAKRTAGMMQ---PHLR-----DKIEK 564
Cdd:PLN02563 650 KE-PFQCLVNQGMIlgeveytafKDSDGEYVSADTADRLGELQ--QEKIPEEKVIKSGDSFVLkddPSIRliaraHKMSK 726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 565 qTRKEF--PDGI-NAYGTDALRYtYYSLASTGRDIK-FDVGRIEGFRNFCNKIWNATNYVLMN---CEDQDCGADGSADY 637
Cdd:PLN02563 727 -SRGNVvnPDDVvSEYGADSLRL-YEMFMGPLRDSKtWSTSGVEGVHRFLGRTWRLVVGAPLPdgsFRDGTVVTDEEPSL 804
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 638 ELSLADKWIISKlqeteiaVAEGVESYRLDLASQALYDFVwneycawylelskpvlwddnaSAAQKKGTR-RTLIRVLEV 716
Cdd:PLN02563 805 EQLRLLHKCIAK-------VTEEIESTRFNTAISAMMEFT---------------------NAAYKWDKVpREAIEPFVL 856
|
890 900 910 920
....*....|....*....|....*....|....*....|..
gi 409026056 717 ILRlahPLMPFITEEIWQKVktlaGQSGdTIMHQPYPVADTS 758
Cdd:PLN02563 857 LLS---PYAPHLAEELWFRL----GHSN-SLAYEPWPEANPS 890
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
16-808 |
2.77e-38 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 154.88 E-value: 2.77e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 16 QTWEKNGYFKPSGK---GDP-YCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGIATQMVVERL 91
Cdd:PLN02882 19 SLWSEIDAFKTQLKrteGLPeYIFYDGPPFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFGWDCHGLPVEYEIDKK 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 92 LdaeGVSRHD----LGREKFLEK----VWQWKEESGGTITRqlrrLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLI 163
Cdd:PLN02882 99 L---GIKRRDdvlkMGIDKYNEEcrsiVTRYSKEWEKTVTR----TGRWIDFENDYKTMDPKFMESVWWVFKQLFEKGLV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 164 YRGKR-----------LVNWDPKL-HTAVSDLEVIseeekgflwhFRYPLADGS-GHIVVA-TTRPETMLGDTAVAVHPE 229
Cdd:PLN02882 172 YKGFKvmpystacktpLSNFEAGLnYKDVSDPAVM----------VSFPIVGDPdNASFVAwTTTPWTLPSNLALCVNPN 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 230 -----------------------------------------DERYQ--------QLVGKMIK------LPLTDREIPIIA 254
Cdd:PLN02882 242 ftyvkvrnkytgkvyivaesrlsalptakpkskkgskpenaAEGYEvlakvpgsSLVGKKYEplfdyfSEFSDTAFRVVA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 255 DDYVDKDFGTGCVKITPAHDFNDYEMGKRHNlpII---NILTDDADLN----DDVPEkYRGMERFAARKQIVADFEALGL 327
Cdd:PLN02882 322 DDYVTDDSGTGVVHCAPAFGEDDYRVCLANG--IIekgGNLPVPVDDDgcftEKVTD-FSGRYVKDADKDIIAAIKAKGR 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 328 LEKIDDHVLKVPRGDRTGVVIEPYLTDQWYVKTAPLAEQAIKAVEDgdIKFVPQQY-ENMYFSWMRDIQDWCISRQLWWG 406
Cdd:PLN02882 399 LVKSGSITHSYPFCWRSDTPLIYRAVPSWFVKVEEIKDRLLENNKQ--TYWVPDYVkEKRFHNWLENARDWAVSRSRFWG 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 407 HRIPAWYDAEGN-IYVGRSEAD------VRAEN---NLPDDLE-----------LKQDDDVLDTWFSSGLWTFGTLGWP- 464
Cdd:PLN02882 477 TPLPIWISDDGEeVVVIGSIAEleklsgVKVTDlhrHFIDHITipssrgpefgvLRRVDDVFDCWFESGSMPYAYIHYPf 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 465 ENTEELKTFHPTDVLVTGFDIIFFWV-ARMIMLTLHFRKEiPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDgidle 543
Cdd:PLN02882 557 ENKELFEKNFPADFVAEGLDQTRGWFyTLMVLSTALFDKP-AFKNLICNGLVLAEDGKKMSKSLKNYPDPNEVID----- 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 544 slvakrtagmmqphlrdkiekqtrkefpdginAYGTDALR-YTYYSLASTGRDIKFdvgRIEGFRNFCNKI----WNATN 618
Cdd:PLN02882 631 --------------------------------KYGADALRlYLINSPVVRAEPLRF---KEEGVFGVVKDVflpwYNAYR 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 619 YVLMNCEDQDcgADGSADY-ELSLA---------DKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNeYCAWYLEL 688
Cdd:PLN02882 676 FLVQNAKRLE--VEGGAPFvPLDLAklqnsanvlDRWINSATQSLVKFVREEMGAYRLYTVVPYLVKFIDN-LTNIYVRF 752
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 689 SKPVLW-----DDNASAAQkkgtrrTLIRVLEVILRLAHPLMPFITEEIWQKVKTLAGQSGDTIMHQPYPVADTSKIDAA 763
Cdd:PLN02882 753 NRKRLKgrtgeEDCRTALS------TLYNVLLTSCKVMAPFTPFFTEVLYQNLRKVLPGSEESIHYCSFPQVDEGELDER 826
|
890 900 910 920
....*....|....*....|....*....|....*....|....*...
gi 409026056 764 AIADLEWIKQAVVAVRNIRGEMNI---APGKAIpvLVVNANTDDLRRI 808
Cdd:PLN02882 827 IEQSVSRMQTVIELARNIRERHNKplkTPLKEM--VVVHPDAEFLDDI 872
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
39-598 |
3.03e-38 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 146.22 E-value: 3.03e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 39 PPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGIATQMVVERLLDAEGVS-RHDLGREKFLEK----VWQ 113
Cdd:cd00818 9 PPYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIELKVEKELGISGKKdIEKMGIAEFNAKcrefALR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 114 WKEESggtiTRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLIYRGKRLVNWdpklhtavsdleviseeekgf 193
Cdd:cd00818 89 YVDEQ----EEQFQRLGVWVDWENPYKTMDPEYMESVWWVFKQLHEKGLLYRGYKVVPW--------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 194 lwhfrypladgsghivvattrpetmlgdtavavhpederyqqlvgkmiklpltdreipiiaddyvdkdfgtgcvkitpah 273
Cdd:cd00818 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 274 dfndyemgkrhnlPIIniltddadlnddvpekYRgmerfaarkqivadfealgllekiddhvlkvprgdrtgvviepyLT 353
Cdd:cd00818 144 -------------PLI----------------YR--------------------------------------------AT 150
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 354 DQWYVKTAPLAEQAIKAVEDgdIKFVPQQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDAEGniyvgrseadvraenn 433
Cdd:cd00818 151 PQWFIRVTKIKDRLLEANDK--VNWIPEWVKNRFGNWLENRRDWCISRQRYWGTPIPVWYCEDC---------------- 212
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 434 lpDDLELKQDDDVLDTWFSSGLWTFGTLGWPENTEELKTFHPTDVLVTGFDIIFFWVARMIMLTLHFRKEIPFHTVYVHG 513
Cdd:cd00818 213 --GEVLVRRVPDVLDVWFDSGSMPYAQLHYPFENEDFEELFPADFILEGSDQTRGWFYSLLLLSTALFGKAPYKNVIVHG 290
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 514 LVRDSQGQKMSKSKGNVLDPIDLIDgidleslvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRYTYYSLASTG 593
Cdd:cd00818 291 FVLDEDGRKMSKSLGNYVDPQEVVD-------------------------------------KYGADALRLWVASSDVYA 333
|
....*
gi 409026056 594 RDIKF 598
Cdd:cd00818 334 EDLRF 338
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
18-796 |
4.53e-36 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 148.19 E-value: 4.53e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 18 WEKNGYFKPSGK----GDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGIATQMVVER--- 90
Cdd:PTZ00427 85 WKSIDAFNTSNKlaknKKAYIFYDGPPFATGLPHYGHLLAGIIKDCVTRYFYQCGFSVERKFGWDCHGLPIEYEIEKenn 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 91 LLDAEGVSRH--DLGREKFLEKVWQWKEESGGTItrqlRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLIYRGKR 168
Cdd:PTZ00427 165 INKKEDILKMgiDVYNEKCRGIVLKYSNEWVKTV----ERIGRWIDFKNDYKTMDKTFMESVWWVFSELYKNNYVYKSFK 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 169 LVNWDPKLHTAVSDLE-------------VIS----------------EEEKGFLWHFRYPLAD---------------- 203
Cdd:PTZ00427 241 VMPYSCKCNTPISNFElnlnykdtpdpsiIISfvlcsdfpkveeecniEEDKQLLGEKYSVLYNnkrensnngnnnstnn 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 204 ----GSGHIVVATTRPETMLGDTAVAV----------HPEDERY-------------------------QQLVGKMIK-- 242
Cdd:PTZ00427 321 vcyaQHSEILAWTTTPWTLPSNLALCVnehftylrihHVKSNRVvivgecrlewimkelkwnvedlkivNRFKGKELKgl 400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 243 --LPL----------TDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNL--PIINILTDDADLNDdvpekyrg 308
Cdd:PTZ00427 401 ryKPLftnfyekynfKERAYKILADDFVTDDAGTGIVHCAPTYGEDDFRVCKKNGVidPEKNIFIDPLDANG-------- 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 309 meRFAARKQIVADfealgLLEKIDDHVLK--VPRGDR-----TGVVIEPYLtdqWYVKTaPLAEQAIKA----------- 370
Cdd:PTZ00427 473 --YFTNEVEEVQN-----LYIKEADNVIKkkLKNENRllsnnTIVHSYPFC---WRSDT-PLIYRAIPAwfirvsnstne 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 371 -VEDGDIKF-VPQQY-ENMYFSWMRDIQDWCISRQLWWGHRIPAWYDAE-------------------GNI------YVG 422
Cdd:PTZ00427 542 lVKNNETTYwIPAHIkEKKFHNWIKDAKDWCISRNRYWGTPIPIWADEKmetvicvesikhleelsgvKNIndlhrhFID 621
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 423 RSEADVRAENNLPddlELKQDDDVLDTWFSSGLWTFGTLGWPENTEElKTFH---PTDVLVTGFDIIFFWVARMIML-TL 498
Cdd:PTZ00427 622 HIEIKNPKGKTYP---KLKRIPEVFDCWFESGSMPYAKVHYPFSTEK-EDFHkifPADFIAEGLDQTRGWFYTLLVIsTL 697
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 499 HFRKEiPFHTVYVHGLVRDSQGQKMSKSKGNVLDPIDLIDgidleslvakrtagmmqphlrdkiekqtrkefpdginAYG 578
Cdd:PTZ00427 698 LFDKA-PFKNLICNGLVLASDGKKMSKRLKNYPDPLYILD-------------------------------------KYG 739
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 579 TDALR-YTYYSLASTGRDIKFD---VGRI---------EGFRNFCNKIwnaTNYVLMNcEDQDCGADGSADYELSLADKW 645
Cdd:PTZ00427 740 ADSLRlYLINSVAVRAENLKFQekgVNEVvksfilpfyHSFRFFSQEV---TRYECLN-KKQFLFNTDYIYKNDNIMDQW 815
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 646 IISKLQETEIAVAEGVESYRLDLASQALYDFVWNeYCAWYLELSKpvlwDDNASAAQKKGTRR---TLIRVLEVILRLAH 722
Cdd:PTZ00427 816 IFSSVQSLTKSVHTEMKAYKLYNVLPKLLQFIEN-LTNWYIRLNR----DRMRGSLGEENCLQslcTTYRTLHLFTVLMA 890
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 723 PLMPFITEEIWQKVK----------------TLAGQSGDTIMHQPY------PVADTSKIDAAAIADLEWIKQAVVAVRN 780
Cdd:PTZ00427 891 PFTPFITEYIYQQLRrvkstnehnennetgnTKEGDLNRGVIHKSVhfimlpQVDEKYIIDYEIIELIEKMKDVILLGRV 970
|
970
....*....|....*....
gi 409026056 781 IRGEMNIA---PGKAIPVL 796
Cdd:PTZ00427 971 LRERRKVAskkPLKSITIL 989
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
607-779 |
1.65e-27 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 109.95 E-value: 1.65e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 607 RNFCNKIWNA----TNYvlMNCEDQDCGADGSADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVwNEYC 682
Cdd:cd07961 11 RKVLLPLWNAyrffVTY--ANLDGFDPGKDDDAVASLNVLDRWILSRLNSLIKEVTEEMEAYDLYTAVRALLEFI-DELT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 683 AWYLELSKPVLWDDNASAAqKKGTRRTLIRVLEVILRLAHPLMPFITEEIWQKVKTLAGQSGDTIMHQPYPVADTSKIDA 762
Cdd:cd07961 88 NWYIRRNRKRFWGEEGDDD-KLAAYATLYEVLLTLSRLMAPFTPFITEEIYQNLRRELGDAPESVHLLDWPEVDESLIDE 166
|
170
....*....|....*..
gi 409026056 763 AAIADLEWIKQAVVAVR 779
Cdd:cd07961 167 ELEEAMELVREIVELGR 183
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
35-191 |
3.03e-22 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 98.47 E-value: 3.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 35 IMIPPPNvtGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDhagiATQMVVERLLDAEGVSRHDlgrekflekvwqW 114
Cdd:cd00812 6 VMFPYPS--GALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFD----AFGLPAENAAIKIGRDPED------------W 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 115 KEESGGTITRQLRRLGASPDWSRERFTMDDGFYKAVQEVFIQLYKDGLIYRGKRLVNWD----------------PKLHT 178
Cdd:cd00812 68 TEYNIKKMKEQLKRMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNWCklldqwflkysetewkEKLLK 147
|
170
....*....|...
gi 409026056 179 AVSDLEVISEEEK 191
Cdd:cd00812 148 DLEKLDGWPEEVR 160
|
|
| Val_tRNA-synt_C |
pfam10458 |
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA ... |
853-918 |
1.18e-21 |
|
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA synthetases.
Pssm-ID: 431296 [Multi-domain] Cd Length: 66 Bit Score: 89.25 E-value: 1.18e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 409026056 853 DTAAELARLDKEIEKLTKEVVKTEGKLNNPKFVDKAPTEVVDKERERLADFQASIAKLTEQKAKMA 918
Cdd:pfam10458 1 DVEKERARLEKELAKLQKEIERVQGKLANPGFVAKAPAEVVEEEKAKLAELEEQAEKLRERLSKLG 66
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
395-734 |
1.27e-20 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 96.49 E-value: 1.27e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 395 QDWCISRQ-LWWGhrIPawydaegniyvgrseadvraennLPDDlelkqDDDVLDTWFSsGLWTFGT-LGWPENTEEL-- 470
Cdd:PRK11893 199 KDLSISRTnFDWG--IP-----------------------VPGD-----PKHVIYVWFD-ALTNYLTaLGYPDDEELLae 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 471 --KTFHPTDVLVTGFDIIFF----WVARMIMLTLHFRKeipfhTVYVHG-LVRDsqGQKMSKSKGNVLDPIDLIDgidle 543
Cdd:PRK11893 248 lfNKYWPADVHLIGKDILRFhavyWPAFLMAAGLPLPK-----RVFAHGfLTLD--GEKMSKSLGNVIDPFDLVD----- 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 544 slvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRYTYYSLASTGRDIKFDVGRIEGFRN--FCNKIWNATNYVL 621
Cdd:PRK11893 316 --------------------------------EYGVDAVRYFLLREIPFGQDGDFSREAFINRINadLANDLGNLAQRTL 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 622 -MNceDQDCGADGSADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVwneYCAW-YLELSKPvlWddNAS 699
Cdd:PRK11893 364 sMI--AKNFDGKVPEPGALTEADEALLEAAAALLERVRAAMDNLAFDKALEAILALV---RAANkYIDEQAP--W--SLA 434
|
330 340 350
....*....|....*....|....*....|....*...
gi 409026056 700 AAQKKGTRRTLIRVLEVILRLA---HPLMPFITEEIWQ 734
Cdd:PRK11893 435 KTDPERLATVLYTLLEVLRGIAvllQPVMPELAAKILD 472
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
612-778 |
1.04e-17 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 81.80 E-value: 1.04e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 612 KIWNATNYVLMNCEDQDCGADGSADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEYCAWYLELSKP 691
Cdd:cd07960 15 KIRNTFRFLLGNLNDFDPAKDAVPYEELLELDRYALHRLNELIKEVREAYENYEFHKVYQALNNFCTVDLSAFYLDIIKD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 692 VLWDDNASAAQKKGTRRTLIRVLEVILRLAHPLMPFITEEIWQKVKtlAGQSGDTIMHQPYPVADTSKIDAAAIADLEWI 771
Cdd:cd07960 95 RLYCDAKDSLERRSAQTVLYHILDALLKLLAPILPFTAEEVWEHLP--GEKKEESVFLEDWPELPEEWKDEELEEKWEKL 172
|
....*..
gi 409026056 772 KQAVVAV 778
Cdd:cd07960 173 LALRDEV 179
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
389-734 |
3.64e-16 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 82.85 E-value: 3.64e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 389 SWMRD-IQDWCISRQLWWGHRIPawyDAEGN-IYVgrseadvraennlpddlelkqdddvldtWF-------SSglwtfg 459
Cdd:COG0143 217 SWLKEgLQDLSISRDFDWGIPVP---GDPGKvFYV----------------------------WFdaligyiSA------ 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 460 TLGWPENT---EELKTFHPTD----VLVTGFDIIFF----WVArMIM---LTLhfrkeiPfHTVYVHG--LVRdsqGQKM 523
Cdd:COG0143 260 TKGYADDRglpEDFEKYWPAPdtelVHFIGKDIIRFhaiiWPA-MLMaagLPL------P-KKVFAHGflTVE---GEKM 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 524 SKSKGNVLDPIDLIDgidleslvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRYTYYSLASTGRDIKFDVgri 603
Cdd:COG0143 329 SKSRGNVIDPDDLLD-------------------------------------RYGPDALRYYLLREVPFGQDGDFSW--- 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 604 EGFRNFCN-----KIWNATNYVL-M---NCedqdcgaDG--SADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQA 672
Cdd:COG0143 369 EDFVARVNsdlanDLGNLASRTLsMihkYF-------DGkvPEPGELTEADEELLAEAEAALEEVAEAMEAFEFRKALEE 441
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 409026056 673 LYDFVW--NEycawYLELSKPvlW----DDNASAAQKkgTRRTLIRVLEVILRLAHPLMPFITEEIWQ 734
Cdd:COG0143 442 IMALARaaNK----YIDETAP--WklakDEDPERLAT--VLYTLLEALRILAILLKPFLPETAEKILE 501
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
197-323 |
2.73e-13 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 69.11 E-value: 2.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 197 FRYPLADGSGHIVVATTRPETMLGDTAVAVHPED-----------------ERYQQL------VGKMIKL---------- 243
Cdd:pfam13603 12 ITFPVEGTDEKIEVFTTRPDTLMGVTFVALAPEHplveklaeknpevaafiEECKNTseiertSETKEKEgvftglyaih 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 244 PLTDREIPIIADDYVDKDFGTGCVKITPAHDFNDYEMGKRHNLPIIN-ILTDDADLNDDVPEK-------------YRGM 309
Cdd:pfam13603 92 PITGEKIPIWIANFVLMEYGTGAVMAVPAHDQRDFEFAKKYNLPIKPvIQPEDGDLDLDIMTEayteegilvnsgeFDGL 171
|
170
....*....|....
gi 409026056 310 ERFAARKQIVADFE 323
Cdd:pfam13603 172 DSEEAKEAIIKKLE 185
|
|
| Anticodon_Ia_like |
cd07375 |
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This ... |
602-725 |
4.09e-12 |
|
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This domain is found in a variety of class Ia aminoacyl tRNA synthetases, C-terminal to the catalytic core domain. It recognizes and specifically binds to the anticodon of the tRNA. Aminoacyl tRNA synthetases catalyze the transfer of cognate amino acids to the 3'-end of their tRNAs by specifically recognizing cognate from non-cognate amino acids. Members include valyl-, leucyl-, isoleucyl-, cysteinyl-, arginyl-, and methionyl-tRNA synthethases. This superfamily also includes a domain from MshC, an enzyme in the mycothiol biosynthetic pathway.
Pssm-ID: 153408 [Multi-domain] Cd Length: 117 Bit Score: 63.68 E-value: 4.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 602 RIEGFRNFCNKIWNATNYVLMNCEDQDCGADGSadyELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVWNEY 681
Cdd:cd07375 3 RLKQARAFLNRLYRLLSFFRKALGGTQPKWDNE---LLEEADRELLARLQEFIKRTTNALEALDPTTAVQELFKFTNELN 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 409026056 682 caWYLELSKPVLWDDNASAAqkkgTRRTLIRVLEVILRLAHPLM 725
Cdd:cd07375 80 --WYLDELKPALQTEELREA----VLAVLRAALVVLTKLLAPFT 117
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
638-736 |
1.76e-11 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 61.84 E-value: 1.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 638 ELSLADKWIISKLQETEIAVAEGVESYRLDLASQ-ALYDFvWNEYcAWYLELSKPvlwddnasaaqkKGTRRTLIRVLEV 716
Cdd:cd07959 32 ELTFIDRWLLSRLNRLIKETTEAYENMQFREALKeGLYEL-QNDL-DWYRERGGA------------GMNKDLLRRFIEV 97
|
90 100
....*....|....*....|
gi 409026056 717 ILRLAHPLMPFITEEIWQKV 736
Cdd:cd07959 98 WTRLLAPFAPHLAEEIWHEL 117
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
461-584 |
1.55e-10 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 64.82 E-value: 1.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 461 LGWP-ENTEELKTFHPTDVLVTGFDIIFF----WVARMIMLTLhfrkEIPFHtVYVHG-LVRDsqGQKMSKSKGNVLDPI 534
Cdd:PRK12267 239 LGYGsDDDELFKKFWPADVHLVGKDILRFhaiyWPIMLMALGL----PLPKK-VFAHGwWLMK--DGKMSKSKGNVVDPE 311
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 409026056 535 DLIDgidleslvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRY 584
Cdd:PRK12267 312 ELVD-------------------------------------RYGLDALRY 324
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
40-598 |
1.85e-10 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 63.85 E-value: 1.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 40 PNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGIATQMVVErlldAEGVSRHDLgrekflekVWQWKEEsg 119
Cdd:pfam09334 8 PYANGPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAE----KEGITPEEL--------VDRYHEI-- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 120 gtITRQLRRLGASPD-WSRerfTMDDGFYKAVQEVFIQLYKDGLIYRgkrlvnwdpklhtavsdleviseeekgflwhfr 198
Cdd:pfam09334 74 --HREDFKKFNISFDdYGR---TTSERHHELVQEFFLKLYENGYIYE--------------------------------- 115
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 199 ypladgsghivvattrpetmlGDTAVAVHPEDERYqqlvgkmiklpLTDREIPiiaddyvdkdfGTgCvkitpahdfndy 278
Cdd:pfam09334 116 ---------------------KEIEQFYCPSDERF-----------LPDRYVE-----------GT-C------------ 139
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 279 emgkrhnlPIINILTDDADlnddvpeKYRGMERfaarkqivadfealgLLEKIDdhvLKVPRGDRTGVVIEPYLTDQWYV 358
Cdd:pfam09334 140 --------PHCGSEDARGD-------QCENCGR---------------HLEPTE---LINPKCVICGTTPEVKETEHYFF 186
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 359 KTAPLAEQAIKAVEDGDiKFVPQQYENMYFSWMRD-IQDWCISRQLWWGHRIPA--------WYDAEGNiYVGRSEadvr 429
Cdd:pfam09334 187 DLSKFQDKLREWIEENN-PEWPENVKNMVLEWLKEgLKDRAISRDLDWGIPVPGaegkvfyvWLDAPIG-YISATK---- 260
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 430 aennlpddlELKQDDDVLDTWfssglwtfgtlgWPENTeELKTFHptdvlVTGFDIIFF----WVArmIMLTLHFRKeiP 505
Cdd:pfam09334 261 ---------ELSGNEEKWKEW------------WPNDP-DTELVH-----FIGKDIIYFhtifWPA--MLLGAGYRL--P 309
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 506 fHTVYVHGLVrDSQGQKMSKSKGNVLDPIDLIDgidleslvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRYT 585
Cdd:pfam09334 310 -TTVFAHGYL-TYEGGKMSKSRGNVVWPSEALD-------------------------------------RFPPDALRYY 350
|
570
....*....|...
gi 409026056 586 YYSLASTGRDIKF 598
Cdd:pfam09334 351 LARNRPETKDTDF 363
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
380-598 |
2.49e-08 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 56.77 E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 380 PQQYENMYFSWMRD-IQDWCISRQLW-WGHRIPawyDAEGN-IYVgrseadvraennlpddlelkqdddvldtWF----- 451
Cdd:cd00814 164 PENARNEVLSWLKEgLKDLSITRDLFdWGIPVP---LDPGKvIYV----------------------------WFdalig 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 452 ---SSGLWTfgtlGWPENTEELKTFHPTDVLVTGFDIIffwvarmimltlhfrkeiPFHTVY-----------------V 511
Cdd:cd00814 213 yisATGYYN----EEWGNSWWWKDGWPELVHFIGKDII------------------RFHAIYwpamllgaglplptrivA 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 512 HGLVRDSqGQKMSKSKGNVLDPIDLIDgidleslvakrtagmmqphlrdkiekqtrkefpdginAYGTDALRYTYYSLAS 591
Cdd:cd00814 271 HGYLTVE-GKKMSKSRGNVVDPDDLLE-------------------------------------RYGADALRYYLLRERP 312
|
....*..
gi 409026056 592 TGRDIKF 598
Cdd:cd00814 313 EGKDSDF 319
|
|
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
9-757 |
1.81e-05 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 48.91 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 9 SIETQWYQTWEKNGYF------KPSGKGDPYCIMIPPPNVTGSLHMGHGFQESIMDALIRYNRMKGKNTLWQVGTDHAGI 82
Cdd:PLN02959 17 EIEVAVQKWWEEEKVFeaeagdEPPKPGEKFFGNFPYPYMNGLLHLGHAFSLSKLEFAAAYHRLRGANVLLPFAFHCTGM 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 83 ----------------------------ATQMVVERLLDAEGVSRHDlgrEKFLEKVWQWKEESGGTIT----------- 123
Cdd:PLN02959 97 pikasadklareiqqygnppvfpeededEAAAVAAAKAEAEAAAAPP---DKFKGKKSKAVAKSGTQKYqweimrsfglp 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 124 ----------------------RQLRRLGASPDWSRERFTMD-DGFYKA-VQEVFIQLYKDGLIYRGKRLVNWDPKLHTA 179
Cdd:PLN02959 174 dseiakfqdpyhwlsyfpplakEDLKAFGLGCDWRRSFITTDvNPYYDAfVRWQFRKLKKKGKIVKDKRYTIYSPLDGQP 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 180 VSD------------------LEVISEeekgFLWHFRyPLADGSGHIVVATTRPETMLGDTAVAVHPE------------ 229
Cdd:PLN02959 254 CADhdrasgegvgpqeyvlikMEVLPP----FPGKLK-ALEGKKVFLAAATLRPETMYGQTNCWVLPDgkygayeindte 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 230 ----DER------YQQ------------------LVGKMIKLPLTDREI----PIIAddyVDKDFGTGCVKITPAHDFND 277
Cdd:PLN02959 329 vfilTARaalnlaYQNfskvpgkptclveltgydLIGLPLKSPLAFNEViyalPMLT---ILTDKGTGVVTSVPSDSPDD 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 278 Y----EMGKRHNL-----------------PIINI--LTDDA------DL-----NDDvpEKYRGMER------FAARKQ 317
Cdd:PLN02959 406 YmalsDLKAKPALrakygvkdewvlpfevvPIINIpeFGDKSaekvceDLkiksqNDK--EKLAEAKRltylkgFTDGTM 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 318 IVADFEALG-----------LLEKIDDHVLKVPRG---DRTG---VVIepyLTDQWYVKTAplAEQAIKAVEDGDIKFvp 380
Cdd:PLN02959 484 LVGEYAGRKvqeakplikkkLIEAGQAILYSEPEKkvmSRSGdecVVA---LTDQWYLTYG--EEEWKKKAEKCLSKM-- 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 381 qqyeNMY-----------FSWMRdiqDWCISRQLWWGHRIP-----------------AWYDA-----EGNIYvGRSEAD 427
Cdd:PLN02959 557 ----NLYsdetrhgfehtLGWLN---QWACSRSFGLGTRIPwdeqflieslsdstiymAYYTVahllqGGDMY-GKDKSS 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 428 VRaennlPDDLelkqDDDVLDTWFSSGLWTFGTLGWPENTEELKT----FHPTDVLVTGFDII------FFWVARMIMLT 497
Cdd:PLN02959 629 IK-----PEQM----TDEVWDFVFCGGPLPKSSDIPAELLEKMKQefeyWYPFDLRVSGKDLIqnhltfAIYNHTAIWAE 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 498 LHFRKEIpfhtvYVHG-LVRDSqgQKMSKSKGNVldpidlidgidleslvakRTagmmqphLRDKIEKqtrkefpdgina 576
Cdd:PLN02959 700 EHWPRGF-----RCNGhLMLNS--EKMSKSTGNF------------------LT-------LRQAIEE------------ 735
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 577 YGTDALRytyYSLASTGRDIKfDVgriegfrNFCNKIWNATNYVLMNcED---QDCGADGS---ADYELSLADKWIiskL 650
Cdd:PLN02959 736 FSADATR---FALADAGDGVD-DA-------NFVFETANAAILRLTK-EIawmEEVLAAESslrTGPPSTYADRVF---E 800
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 651 QETEIAVAEGVESYRLDLASQALydfvwneYCAWY-LELSKpvlwDDNASAAQKKGTRRTLI-RVLEVILRLAHPLMPFI 728
Cdd:PLN02959 801 NEINIAIAETEKNYEAMMFREAL-------KSGFYdLQAAR----DEYRLSCGSGGMNRDLVwRFMDVQTRLITPICPHY 869
|
970 980
....*....|....*....|....*....
gi 409026056 729 TEEIWQKvktLAGQSGdTIMHQPYPVADT 757
Cdd:PLN02959 870 AEHVWRE---ILKKEG-FAVTAGWPVAGE 894
|
|
| Anticodon_Ia_Leu_BEm |
cd07958 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; ... |
603-735 |
9.94e-05 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes bacterial and eukaryotic mitochondrial members, as well as LeuRS from the archaeal Halobacteria. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153412 [Multi-domain] Cd Length: 117 Bit Score: 42.59 E-value: 9.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 409026056 603 IEGFRNFCNKIWNATNyvlmncEDQDCGADGSADYELSLADKWIISKLQETEIAVAEGVESYRLDLASQALYDFVwNEyc 682
Cdd:cd07958 6 VEGAYRFLNRVWRLVT------ELAEALAAPAAAAELSEEDKELRRKLHKTIKKVTEDIERLRFNTAIAALMELV-NA-- 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 409026056 683 awyleLSKpVLWDDNASAAQKKgtrrtliRVLEVILRLAHPLMPFITEEIWQK 735
Cdd:cd07958 77 -----LYK-YKKKDAQHAAVLR-------EALETLVLLLAPFAPHIAEELWEE 116
|
|
| Plantacyanin |
cd11013 |
Plantacyanin is a subclass of phytocyanins, plant type I copper proteins; Plantacyanins belong ... |
453-480 |
7.90e-03 |
|
Plantacyanin is a subclass of phytocyanins, plant type I copper proteins; Plantacyanins belong to the phytocyanin family of blue copper proteins, a ubiquitous family of plant cupredoxins. Plantacyanin is involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. The exact function of plantacyanin is unknown. However plantacyanin is shown to play a role in reproduction in Arabidopsis. Plantacyanins may also be stress-related proteins and be involved in plant defense responses.
Pssm-ID: 259899 Cd Length: 95 Bit Score: 36.56 E-value: 7.90e-03
10 20
....*....|....*....|....*...
gi 409026056 453 SGLWTFGTLGWPENteelKTFHPTDVLV 480
Cdd:cd11013 8 SIGWTFGVVGWPNG----KTFRAGDVLV 31
|
|
| LysS |
COG1384 |
Lysyl-tRNA synthetase, class I [Translation, ribosomal structure and biogenesis]; Lysyl-tRNA ... |
505-545 |
9.45e-03 |
|
Lysyl-tRNA synthetase, class I [Translation, ribosomal structure and biogenesis]; Lysyl-tRNA synthetase, class I is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440994 [Multi-domain] Cd Length: 525 Bit Score: 39.41 E-value: 9.45e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 409026056 505 PFHTVYvhGLVRDSQGQKMSKSKGNVLDPIDLIDGIDLESL 545
Cdd:COG1384 272 PEGFVY--ELFLDENGEKISKSKGNGLTVEEWLEYAEPESL 310
|
|
| |
