NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|357542055|gb|AET84815|]
View 

hypothetical protein MPXG_00017 [Micromonas pusilla virus SP1]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 10789277)

class I SAM-dependent methyltransferase is an enzyme that uses S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyl transfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0008168|GO:1904047
PubMed:  12826405
SCOP:  3000118

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 10-123 1.94e-19

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


:

Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 80.81  E-value: 1.94e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  10 DTKKSLIQSVA-KEGQSILDVGCGFGGDLQKWHKCGVNINMCDPEPSALVEARSRAKNMHIRVNFYEGDIHNCP--NRKY 86
Cdd:COG2226    9 DGREALLAALGlRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGLNVEFVVGDAEDLPfpDGSF 88

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 357542055  87 DILCYNFSLHYIfkskSYFFSSIREIKKRLKPGGKLI 123
Cdd:COG2226   89 DLVISSFVLHHL----PDPERALAEIARVLKPGGRLV 121
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 10-123 1.94e-19

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 80.81  E-value: 1.94e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  10 DTKKSLIQSVA-KEGQSILDVGCGFGGDLQKWHKCGVNINMCDPEPSALVEARSRAKNMHIRVNFYEGDIHNCP--NRKY 86
Cdd:COG2226    9 DGREALLAALGlRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGLNVEFVVGDAEDLPfpDGSF 88

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 357542055  87 DILCYNFSLHYIfkskSYFFSSIREIKKRLKPGGKLI 123
Cdd:COG2226   89 DLVISSFVLHHL----PDPERALAEIARVLKPGGRLV 121
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 26-120 1.11e-16

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 72.21  E-value: 1.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   26 ILDVGCGFGGDLQKWHK-CGVNINMCDPEPSALVEARSRAKNMHIRVNFYEGDIHNCP--NRKYDILCYNFSLHYIfkSK 102
Cdd:pfam13649   1 VLDLGCGTGRLTLALARrGGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAEDLPfpDGSFDLVVSSGVLHHL--PD 78

                          90
                  ....*....|....*...
gi 357542055  103 SYFFSSIREIKKRLKPGG 120
Cdd:pfam13649  79 PDLEAALREIARVLKPGG 96
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 26-123 1.50e-10

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 56.28  E-value: 1.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  26 ILDVGCGFGGDLQKWHK-CGVNINMCDPEPSALVEARS-RAKNMHIRVNFYEGDIHN---CPNRKYDILCYNFSLHYIFK 100
Cdd:cd02440    2 VLDLGCGTGALALALASgPGARVTGVDISPVALELARKaAAALLADNVEVLKGDAEElppEADESFDVIISDPPLHHLVE 81

                         90       100
                 ....*....|....*....|...
gi 357542055 101 SksyFFSSIREIKKRLKPGGKLI 123
Cdd:cd02440   82 D---LARFLEEARRLLKPGGVLV 101
PRK08317 PRK08317
hypothetical protein; Provisional
 21-142 7.84e-06

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 45.31  E-value: 7.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  21 KEGQSILDVGCGFGGDLQKW--------HKCGVninmcDPEPSALVEARSRAKNMHIRVNFYEGDIHNCPNRK--YDILC 90
Cdd:PRK08317  18 QPGDRVLDVGCGPGNDARELarrvgpegRVVGI-----DRSEAMLALAKERAAGLGPNVEFVRGDADGLPFPDgsFDAVR 92

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 357542055  91 YNFSLHYIfKSKSyffSSIREIKKRLKPGGKLIGIIPDSEKIMFRIPYRDDM 142
Cdd:PRK08317  93 SDRVLQHL-EDPA---RALAEIARVLRPGGRVVVLDTDWDTLVWHSGDRALM 140
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 24-123 4.04e-03

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 37.27  E-value: 4.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   24 QSILDVGCGFGGDLQKWHKCG--VNINMCDPEPSALVEARSRAKnmhIRVNFYEGDIHNCP--NRKYDILCYNFSLHYiF 99
Cdd:TIGR02072  36 ASVLDIGCGTGYLTRALLKRFpqAEFIALDISAGMLAQAKTKLS---ENVQFICGDAEKLPleDSSFDLIVSNLALQW-C 111

                          90       100
                  ....*....|....*....|....
gi 357542055  100 KSKSYFFSSIREIkkrLKPGGKLI 123
Cdd:TIGR02072 112 DDLSQALSELARV---LKPGGLLA 132
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 10-123 1.94e-19

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 80.81  E-value: 1.94e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  10 DTKKSLIQSVA-KEGQSILDVGCGFGGDLQKWHKCGVNINMCDPEPSALVEARSRAKNMHIRVNFYEGDIHNCP--NRKY 86
Cdd:COG2226    9 DGREALLAALGlRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGLNVEFVVGDAEDLPfpDGSF 88

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 357542055  87 DILCYNFSLHYIfkskSYFFSSIREIKKRLKPGGKLI 123
Cdd:COG2226   89 DLVISSFVLHHL----PDPERALAEIARVLKPGGRLV 121
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 14-123 7.61e-17

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 73.51  E-value: 7.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  14 SLIQSVAKEGQSILDVGCGFGGDLQKWHKCGVNINMCDPEPSALVEARSRAKnmHIRVNFYEGDIHNCP--NRKYDILCY 91
Cdd:COG2227   16 ALLARLLPAGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAA--ELNVDFVQGDLEDLPleDGSFDLVIC 93

                         90       100       110
                 ....*....|....*....|....*....|..
gi 357542055  92 NFSLHYIFKSKSYffssIREIKKRLKPGGKLI 123
Cdd:COG2227   94 SEVLEHLPDPAAL----LRELARLLKPGGLLL 121
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 26-120 1.11e-16

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 72.21  E-value: 1.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   26 ILDVGCGFGGDLQKWHK-CGVNINMCDPEPSALVEARSRAKNMHIRVNFYEGDIHNCP--NRKYDILCYNFSLHYIfkSK 102
Cdd:pfam13649   1 VLDLGCGTGRLTLALARrGGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAEDLPfpDGSFDLVVSSGVLHHL--PD 78

                          90
                  ....*....|....*...
gi 357542055  103 SYFFSSIREIKKRLKPGG 120
Cdd:pfam13649  79 PDLEAALREIARVLKPGG 96
Pox_MCEL pfam03291
mRNA capping enzyme; This family of enzymes are related to pfam03919.
 6-132 2.34e-16

mRNA capping enzyme; This family of enzymes are related to pfam03919.


Pssm-ID: 281307 [Multi-domain]  Cd Length: 332  Bit Score: 76.32  E-value: 2.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055    6 RNHNDTKKS-LIQSVAKEG------QSILDVGCGFGGDLQKWHKCGVNINMC-DPEPSALVEARSR-----AKNMHIRVN 72
Cdd:pfam03291  40 RNFNNWIKSlLISLYASKTfqnsnkRKVLDLGCGKGGDLEKWFKGGISQLIGtDIAEVSIEQCRERynklrSGNKSKYYK 119

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 357542055   73 F-YE-----------GDIHNCPNRKYDILCYNFSLHYIFKSKSYFFSSIREIKKRLKPGGKLIGIIPDSEKI 132
Cdd:pfam03291 120 FdAEfitgdcfvsslREVFEDPFGKFDIVSCQFAIHYSFESEEKARTMLRNVAELLASGGVFIGTTPDSDFI 191
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 21-160 1.50e-15

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 71.87  E-value: 1.50e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  21 KEGQSILDVGCGFGGDLQ------KWHKCGVninmcDPEPSALVEARSRAKNMHI-RVNFYEGDIHNC---PNRKYDILC 90
Cdd:COG0500   25 PKGGRVLDLGCGTGRNLLalaarfGGRVIGI-----DLSPEAIALARARAAKAGLgNVEFLVADLAELdplPAESFDLVV 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  91 YNFSLHYIfkSKSYFFSSIREIKKRLKPGGKLIGIIPDSEKIMFRIPYRDDMGNYFLMSKHCGGGYGEKM 160
Cdd:COG0500  100 AFGVLHHL--PPEEREALLRELARALKPGGVLLLSASDAAAALSLARLLLLATASLLELLLLLRLLALEL 167
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 27-122 1.82e-11

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 58.53  E-value: 1.82e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   27 LDVGCGFGGDLQKW--HKCGVNINMCDPEPSALVEARSRAKNMHI----RVNFYEGDIHNCPNRKYDILCYNFSLHYIFk 100
Cdd:pfam08242   1 LEIGCGTGTLLRALleALPGLEYTGLDISPAALEAARERLAALGLlnavRVELFQLDLGELDPGSFDVVVASNVLHHLA- 79

                          90       100
                  ....*....|....*....|..
gi 357542055  101 sksYFFSSIREIKKRLKPGGKL 122
Cdd:pfam08242  80 ---DPRAVLRNIRRLLKPGGVL 98
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 26-123 1.50e-10

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 56.28  E-value: 1.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  26 ILDVGCGFGGDLQKWHK-CGVNINMCDPEPSALVEARS-RAKNMHIRVNFYEGDIHN---CPNRKYDILCYNFSLHYIFK 100
Cdd:cd02440    2 VLDLGCGTGALALALASgPGARVTGVDISPVALELARKaAAALLADNVEVLKGDAEElppEADESFDVIISDPPLHHLVE 81

                         90       100
                 ....*....|....*....|...
gi 357542055 101 SksyFFSSIREIKKRLKPGGKLI 123
Cdd:cd02440   82 D---LARFLEEARRLLKPGGVLV 101
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
22-123 1.61e-10

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 55.99  E-value: 1.61e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  22 EGQSILDVGCGFGGD----LQKWHKC---GVninmcDPEPSALVEARSRAKNmhirVNFYEGDIHN-CPNRKYDILCYNF 93
Cdd:COG4106    1 PPRRVLDLGCGTGRLtallAERFPGArvtGV-----DLSPEMLARARARLPN----VRFVVADLRDlDPPEPFDLVVSNA 71

                         90       100       110
                 ....*....|....*....|....*....|
gi 357542055  94 SLHYIFKSKSYFfssiREIKKRLKPGGKLI 123
Cdd:COG4106   72 ALHWLPDHAALL----ARLAAALAPGGVLA 97
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 27-123 9.47e-10

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 53.82  E-value: 9.47e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   27 LDVGCGFGGDLQKWHKCGVNINMCDPEPSALVEARSRAKNMHirVNFYEGDIHNCP--NRKYDILCYNFSLHYIfkskSY 104
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREG--LTFVVGDAEDLPfpDNSFDLVLSSEVLHHV----ED 74

                          90
                  ....*....|....*....
gi 357542055  105 FFSSIREIKKRLKPGGKLI 123
Cdd:pfam08241  75 PERALREIARVLKPGGILI 93
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 21-123 2.85e-09

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 54.17  E-value: 2.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  21 KEGQSILDVGCGFGGD---LQKWHKC---GVNInmcDPEPSALVEARSRAKNMHIRVNFYEGDIHN-CPNRKYD-ILCYN 92
Cdd:COG2230   50 KPGMRVLDIGCGWGGLalyLARRYGVrvtGVTL---SPEQLEYARERAAEAGLADRVEVRLADYRDlPADGQFDaIVSIG 126

                         90       100       110
                 ....*....|....*....|....*....|...
gi 357542055  93 FSLHyiFKSKSY--FFssiREIKKRLKPGGKLI 123
Cdd:COG2230  127 MFEH--VGPENYpaYF---AKVARLLKPGGRLL 154
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 21-131 9.49e-09

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 52.42  E-value: 9.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   21 KEGQSILDVGCGFGGDLQKWH-KCGVNINMC--DPEPSALVEARSRA-KNMHIRVNFYEGDIHNCPN----RKYDILCYN 92
Cdd:pfam13847   2 DKGMRVLDLGCGTGHLSFELAeELGPNAEVVgiDISEEAIEKARENAqKLGFDNVEFEQGDIEELPElledDKFDVVISN 81

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 357542055   93 FSLHYIFKSKSYFfssiREIKKRLKPGGKLIGIIPDSEK 131
Cdd:pfam13847  82 CVLNHIPDPDKVL----QEILRVLKPGGRLIISDPDSLA 116
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 21-130 1.59e-06

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 46.27  E-value: 1.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   21 KEGQSILDVGCGFGGDLQKWHKCGVNINMCDPEPsalvEARSRAKNMHIRVNFYEGDIhNCPNRKYDILCYNFSLHYIFK 100
Cdd:pfam13489  21 PSPGRVLDFGCGTGIFLRLLRAQGFSVTGVDPSP----IAIERALLNVRFDQFDEQEA-AVPAGKFDVIVAREVLEHVPD 95

                          90       100       110
                  ....*....|....*....|....*....|
gi 357542055  101 SKSYffssIREIKKRLKPGGKLIGIIPDSE 130
Cdd:pfam13489  96 PPAL----LRQIAALLKPGGLLLLSTPLAS 121
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
20-130 4.75e-06

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 45.37  E-value: 4.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  20 AKEGQSILDVGCGFGGDLQKWHKCGVNINMCDPEPSALVEARSRAknmhIRVNFYEGDIHNC--PNRKYDILCYNFSLHY 97
Cdd:COG4976   44 PGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKG----VYDRLLVADLADLaePDGRFDLIVAADVLTY 119

                         90       100       110
                 ....*....|....*....|....*....|...
gi 357542055  98 IFKSKSYFfssiREIKKRLKPGGKLIGIIPDSE 130
Cdd:COG4976  120 LGDLAAVF----AGVARALKPGGLFIFSVEDAD 148
PRK08317 PRK08317
hypothetical protein; Provisional
 21-142 7.84e-06

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 45.31  E-value: 7.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  21 KEGQSILDVGCGFGGDLQKW--------HKCGVninmcDPEPSALVEARSRAKNMHIRVNFYEGDIHNCPNRK--YDILC 90
Cdd:PRK08317  18 QPGDRVLDVGCGPGNDARELarrvgpegRVVGI-----DRSEAMLALAKERAAGLGPNVEFVRGDADGLPFPDgsFDAVR 92

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 357542055  91 YNFSLHYIfKSKSyffSSIREIKKRLKPGGKLIGIIPDSEKIMFRIPYRDDM 142
Cdd:PRK08317  93 SDRVLQHL-EDPA---RALAEIARVLRPGGRVVVLDTDWDTLVWHSGDRALM 140
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
15-126 1.01e-04

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 42.08  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055  15 LIQSVAKEGQSILDVGCGFG----GDLQKWHKcgvNINMCDPEPSALVEARSRAK--NMHIRVNFYEGDIhnCPNRKYDI 88
Cdd:COG2264  141 ALEKLLKPGKTVLDVGCGSGilaiAAAKLGAK---RVLAVDIDPVAVEAARENAElnGVEDRIEVVLGDL--LEDGPYDL 215

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 357542055  89 LCYNfslhyifksksyffssI---------REIKKRLKPGGKLI--GII 126
Cdd:COG2264  216 VVAN----------------IlanplielaPDLAALLKPGGYLIlsGIL 248
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 24-123 4.04e-03

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 37.27  E-value: 4.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   24 QSILDVGCGFGGDLQKWHKCG--VNINMCDPEPSALVEARSRAKnmhIRVNFYEGDIHNCP--NRKYDILCYNFSLHYiF 99
Cdd:TIGR02072  36 ASVLDIGCGTGYLTRALLKRFpqAEFIALDISAGMLAQAKTKLS---ENVQFICGDAEKLPleDSSFDLIVSNLALQW-C 111

                          90       100
                  ....*....|....*....|....
gi 357542055  100 KSKSYFFSSIREIkkrLKPGGKLI 123
Cdd:TIGR02072 112 DDLSQALSELARV---LKPGGLLA 132
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
21-151 5.22e-03

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 37.03  E-value: 5.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357542055   21 KEGQSILDVGCGFGG---DLQKWHKCGVNINMCDPEPSALVEARSRAKNM-HIRVNFYEGDIHNCPNRK--YDILCYNFS 94
Cdd:pfam01209  41 KRGNKFLDVAGGTGDwtfGLSDSAGSSGKVVGLDINENMLKEGEKKAKEEgKYNIEFLQGNAEELPFEDdsFDIVTISFG 120

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 357542055   95 LhyifKSKSYFFSSIREIKKRLKPGGKLIgIIPDSEKIMFriPYRDdmgNYFLMSKH 151
Cdd:pfam01209 121 L----RNFPDYLKVLKEAFRVLKPGGRVV-CLEFSKPENP--LLSQ---AYELYFKY 167
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH