|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
1-387 |
0e+00 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 694.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 1 MNKEELLTEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNV-DGDIVEFDI 79
Cdd:PRK05322 1 MMKEELKKKFAEVFGEEAEDVFFSPGRINLIGEHTDYNGGHVFPAAITLGTYGAARKRDDKKVRLYSANFeDLGIIEFDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 80 DDTTVEKDDRfWANYFKGMITYLREKYDNINHGFNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDVDRIVLAKMGQ 159
Cdd:PRK05322 81 DDLSFDKEDD-WANYPKGVLKFLQEAGYKIDHGFDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLDLDRLELVKLGQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 160 RTENEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGEYEIIIMATNKPHTLADSAYNDRVRECHDAVKKLQ 239
Cdd:PRK05322 160 KTENEFIGVNSGIMDQFAIGMGKKDHAILLDCNTLEYEYVPLDLGDYVIVIMNTNKRRELADSKYNERRAECEKALEELQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 240 QKLDIKALGELDNDTFDEYSYLIDNETELKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHYDYEVTGKELD 319
Cdd:PRK05322 240 KKLDIKSLGELTEEEFDEYSYLIKDETLLKRARHAVTENQRTLKAVKALKAGDLEKFGRLMNASHVSLRDDYEVTGLELD 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 327183963 320 TLAEASWKQPGVLGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIYRDKIGYDASFYDAEIVDGTKRI 387
Cdd:PRK05322 320 TLVEAAWKQEGVLGARMTGAGFGGCAIAIVKKDKVEAFKENVGKAYEEKIGYAASFYVAEIGDGAREL 387
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
3-387 |
5.47e-180 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 505.08 E-value: 5.47e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 3 KEELLTEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNVDgDIVEFDIDDT 82
Cdd:COG0153 2 LERLIEAFEEAFGEEPEGVFSAPGRVNLIGEHTDYNGGFVLPAAIDRGTYAAARPRDDRKVRVYSADFD-EEVEFDLDDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 83 TVEKDDRfWANYFKGMITYLREKYDNInHGFNLYIK-------------AnlpsgsglsssaaIEMLMGIILKDEFNLDV 149
Cdd:COG0153 81 EPGEEDG-WANYVRGVAWALQERGYKL-GGFDLVIDgdvplgaglsssaA-------------LEVAVALALNDLFGLGL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 150 DRIVLAKMGQRTENEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGEYEIIIMATNKPHTLADSAYNDRVR 229
Cdd:COG0153 146 DPVELAKIGQRAENEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPLEGYALVIVDTNVKHSLADSEYNERRA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 230 ECHDAVKKLqqklDIKALGELDNDTFDEYSYLIDNETELKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHY 309
Cdd:COG0153 226 ECEAAAAIL----GVKSLRDVTLEDLEAARARLGDEVLRRRARHVVTENQRVLEAVEALRAGDLEAFGKLMNASHASLRD 301
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 327183963 310 DYEVTGKELDTLAEASWKQPGVLGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIYRDKIGYDASFYDAEIVDGTKRI 387
Cdd:COG0153 302 DYEVSCPELDTLVELALAEAGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEKTGLEPDFYVVKPSDGARRL 379
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
3-383 |
2.98e-118 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 348.35 E-value: 2.98e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 3 KEELLTEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNVDGDIVEFDIDDT 82
Cdd:TIGR00131 1 CESIQKIFASAFGAKPDFTARAPGRVNLIGEHTDYNDGSVLPCAIDFGTLCAVAVRDDKNVRIYLANADNKFAERSLDLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 83 TVEKDDRFWANYFKGMITYLREKYDNINHGFNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDVDRIVLAKMGQRTE 162
Cdd:TIGR00131 81 LDGSEVSDWANYFKGVLHVAQERFNSFPLGADIVCSGNVPTGSGLSSSAAFECAVGAVLQNMGHLPLDSKQILLRIQVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 163 NEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGEYEIIIMATNKPHTLADSAYNDRVRECHDAVKKLQQKl 242
Cdd:TIGR00131 161 NHFVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKFPQLGIAFVIANTNVKRTLAPSNYNTRRQECTTAANFLAAT- 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 243 DIKALGELDNDTFDEY---SYLIDNETElKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHYDYEVTGKELD 319
Cdd:TIGR00131 240 DKGALRDFMNEYFARYiarLTKMLPLVE-ERAKHVVSENLRVLKAVKAMKDNDFKQFGALMNESHASCDDDYECTCPEID 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 327183963 320 TLAEASWKQPGVLGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIYRDKIGYDASFYDAEIVDG 383
Cdd:TIGR00131 319 ELVCSAALVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKYPKKTGLELTFYVIVSKPG 382
|
|
| GalKase_gal_bdg |
pfam10509 |
Galactokinase galactose-binding signature; This is the highly conserved galactokinase ... |
8-57 |
4.58e-21 |
|
Galactokinase galactose-binding signature; This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Pssm-ID: 463125 [Multi-domain] Cd Length: 50 Bit Score: 85.20 E-value: 4.58e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 327183963 8 TEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGP 57
Cdd:pfam10509 1 EAFEELFGKEPVGVASAPGRVNLIGEHTDYNGGFVLPAAINLDTYVAVSP 50
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
1-387 |
0e+00 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 694.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 1 MNKEELLTEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNV-DGDIVEFDI 79
Cdd:PRK05322 1 MMKEELKKKFAEVFGEEAEDVFFSPGRINLIGEHTDYNGGHVFPAAITLGTYGAARKRDDKKVRLYSANFeDLGIIEFDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 80 DDTTVEKDDRfWANYFKGMITYLREKYDNINHGFNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDVDRIVLAKMGQ 159
Cdd:PRK05322 81 DDLSFDKEDD-WANYPKGVLKFLQEAGYKIDHGFDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLDLDRLELVKLGQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 160 RTENEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGEYEIIIMATNKPHTLADSAYNDRVRECHDAVKKLQ 239
Cdd:PRK05322 160 KTENEFIGVNSGIMDQFAIGMGKKDHAILLDCNTLEYEYVPLDLGDYVIVIMNTNKRRELADSKYNERRAECEKALEELQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 240 QKLDIKALGELDNDTFDEYSYLIDNETELKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHYDYEVTGKELD 319
Cdd:PRK05322 240 KKLDIKSLGELTEEEFDEYSYLIKDETLLKRARHAVTENQRTLKAVKALKAGDLEKFGRLMNASHVSLRDDYEVTGLELD 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 327183963 320 TLAEASWKQPGVLGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIYRDKIGYDASFYDAEIVDGTKRI 387
Cdd:PRK05322 320 TLVEAAWKQEGVLGARMTGAGFGGCAIAIVKKDKVEAFKENVGKAYEEKIGYAASFYVAEIGDGAREL 387
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
3-387 |
5.47e-180 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 505.08 E-value: 5.47e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 3 KEELLTEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNVDgDIVEFDIDDT 82
Cdd:COG0153 2 LERLIEAFEEAFGEEPEGVFSAPGRVNLIGEHTDYNGGFVLPAAIDRGTYAAARPRDDRKVRVYSADFD-EEVEFDLDDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 83 TVEKDDRfWANYFKGMITYLREKYDNInHGFNLYIK-------------AnlpsgsglsssaaIEMLMGIILKDEFNLDV 149
Cdd:COG0153 81 EPGEEDG-WANYVRGVAWALQERGYKL-GGFDLVIDgdvplgaglsssaA-------------LEVAVALALNDLFGLGL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 150 DRIVLAKMGQRTENEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGEYEIIIMATNKPHTLADSAYNDRVR 229
Cdd:COG0153 146 DPVELAKIGQRAENEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPLEGYALVIVDTNVKHSLADSEYNERRA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 230 ECHDAVKKLqqklDIKALGELDNDTFDEYSYLIDNETELKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHY 309
Cdd:COG0153 226 ECEAAAAIL----GVKSLRDVTLEDLEAARARLGDEVLRRRARHVVTENQRVLEAVEALRAGDLEAFGKLMNASHASLRD 301
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 327183963 310 DYEVTGKELDTLAEASWKQPGVLGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIYRDKIGYDASFYDAEIVDGTKRI 387
Cdd:COG0153 302 DYEVSCPELDTLVELALAEAGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEKTGLEPDFYVVKPSDGARRL 379
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
3-383 |
2.98e-118 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 348.35 E-value: 2.98e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 3 KEELLTEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNVDGDIVEFDIDDT 82
Cdd:TIGR00131 1 CESIQKIFASAFGAKPDFTARAPGRVNLIGEHTDYNDGSVLPCAIDFGTLCAVAVRDDKNVRIYLANADNKFAERSLDLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 83 TVEKDDRFWANYFKGMITYLREKYDNINHGFNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDVDRIVLAKMGQRTE 162
Cdd:TIGR00131 81 LDGSEVSDWANYFKGVLHVAQERFNSFPLGADIVCSGNVPTGSGLSSSAAFECAVGAVLQNMGHLPLDSKQILLRIQVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 163 NEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGEYEIIIMATNKPHTLADSAYNDRVRECHDAVKKLQQKl 242
Cdd:TIGR00131 161 NHFVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKFPQLGIAFVIANTNVKRTLAPSNYNTRRQECTTAANFLAAT- 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 243 DIKALGELDNDTFDEY---SYLIDNETElKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHYDYEVTGKELD 319
Cdd:TIGR00131 240 DKGALRDFMNEYFARYiarLTKMLPLVE-ERAKHVVSENLRVLKAVKAMKDNDFKQFGALMNESHASCDDDYECTCPEID 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 327183963 320 TLAEASWKQPGVLGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIYRDKIGYDASFYDAEIVDG 383
Cdd:TIGR00131 319 ELVCSAALVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKYPKKTGLELTFYVIVSKPG 382
|
|
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
3-376 |
8.45e-93 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 283.35 E-value: 8.45e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 3 KEELLTEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNVDGDIVEFDIDDT 82
Cdd:PRK05101 4 KQKTQSLFAQQFGYPPTHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAKRDDRIVRVIAADYDNQQDEFSLDAP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 83 TVEKDDRFWANYFKGMITYLREKYDNINhGFNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDVDRIVLAKMGQRTE 162
Cdd:PRK05101 84 IVPHPEQQWANYVRGVVKHLQERNPDFG-GADLVISGNVPQGAGLSSSASLEVAVGQTFQQLYHLPLSGAEIALNGQEAE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 163 NEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGeYEIIIMATNKPHTLADSAYNDRVRECHDAVKKLQQkl 242
Cdd:PRK05101 163 NQFVGCNCGIMDQLISALGKKDHALLIDCRSLETKAVPMPEG-VAVVIINSNVKRGLVDSEYNTRRQQCETAARFFGV-- 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 243 diKALGELDNDTFDEYSYLIDNETeLKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHYDYEVTGKELDTLA 322
Cdd:PRK05101 240 --KALRDVTLEQFNAVAAELDPVV-AKRARHVITENARTLEAASALAAGDLKRMGELMAESHASMRDDFEITVPQIDTLV 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 327183963 323 E---ASWKQPGvlGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIYRDKIGYDASFY 376
Cdd:PRK05101 317 EivkAVIGDQG--GVRMTGGGFGGCIVALVPEELVEAVRQAVAEQYEAKTGLKETFY 371
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
24-387 |
2.20e-92 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 281.11 E-value: 2.20e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 24 SPGRINVIGEHTDYNGGHVFPAAISLgvYGVYGPREDKKVRLFSGNVdGDIVEFDIDDttVEKDDRfWANYFKGMITYLR 103
Cdd:PRK03817 5 SPGRVNLIGEHTDYNDGYVLPFAINL--YTFLEIEKSEKFIFYSENF-NEEKTFELDK--LEKLNS-WADYIKGVIWVLE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 104 EKYDNINhGFNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDVDRIVLAKMGQRTENEFVGLNSGIMDQFACIMGKK 183
Cdd:PRK03817 79 KRGYEVG-GVKGKVSSNLPIGAGLSSSASLEVAVAYALNEAYNLNLSKLELALLAREAENEFVGVPCGIMDQFAVAFGKK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 184 DSAIFLDCNTLKYEYMPLAlGEYEIIIMATNKPHTLADSAYNDRVRECHDAVKKlqqkldikalgeLDNDTFDEYSY--- 260
Cdd:PRK03817 158 DHAIFLDTMTLEYEYVPFP-EDYEILVFDTGVKRELASSEYNERRQECEEALKI------------LGKKSSKEVTEedl 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 261 --LidNETELKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHYDYEVTGKELDTLAEASwKQPGVLGARMIG 338
Cdd:PRK03817 225 skL--PPLLRKRAGYVLRENERVLKVRDALKEGDIETLGELLTESHWDLADNYEVSCEELDFFVEFA-LELGAYGARLTG 301
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 327183963 339 GGFGGSAIAIVKKSEAENFKKNVGDIYRDKIGYDASFYDAEIVDGTKRI 387
Cdd:PRK03817 302 AGFGGSAIALVDKGKFESIGEELLEEYKKRFGIDPKYFVVESSDGVRKI 350
|
|
| PRK00555 |
PRK00555 |
galactokinase; Provisional |
22-355 |
6.26e-56 |
|
galactokinase; Provisional
Pssm-ID: 179063 [Multi-domain] Cd Length: 363 Bit Score: 187.37 E-value: 6.26e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 22 FFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNVDGDIVefdIDDTTVEKDDRFWANYFKGMITY 101
Cdd:PRK00555 5 YAAPGRINLIGEHTDYNLGFALPIALPQRTVVTFTPEHTDAITASSDRADGSAR---IPLDTTPGQVTGWAAYAAGVIWA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 102 LREKYDNINHGfNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDVDRIVLAKMGQRTENEFVGLNSGIMDQFACIMG 181
Cdd:PRK00555 82 LRGAGHPVPGG-AMSITSDVEIGSGLSSSAALECAVLGAVGAATGTRIDRLEQARLAQRAENEYVGAPTGLLDQLAALFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 182 KKDSAIFLDCNTLKYEYMPLALGEYEIIIMATNK--PHTLADSAYNDRVRECHDAVKKLQQKlDIKALGELDNDTFDEys 259
Cdd:PRK00555 161 APKTALLIDFRDLTVRPVAFDPDAAGVVLLLMDSraRHRHAGGEYAARRASCERAAADLGVS-SLRAVQDRGLAALGA-- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 260 ylIDNETELKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVSLHYDYEVTGKELDTLAEASWKQpGVLGARMIGG 339
Cdd:PRK00555 238 --IADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHASMRDDFEITTERIDLIADSAVRA-GALGARMTGG 314
|
330
....*....|....*.
gi 327183963 340 GFGGSAIAIVKKSEAE 355
Cdd:PRK00555 315 GFGGCVIALVPADRAE 330
|
|
| PLN02865 |
PLN02865 |
galactokinase |
15-366 |
6.86e-46 |
|
galactokinase
Pssm-ID: 215466 [Multi-domain] Cd Length: 423 Bit Score: 162.66 E-value: 6.86e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 15 GEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSGNVDGDiVEFDIDDTTV---------- 84
Cdd:PLN02865 26 NSGEVRVVVSPYRICPLGAHIDHQGGTVSAMTINKGILLGFVPSGDPEVLLRSAQFEGE-VRFRVDEIQHpianvssdsk 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 85 EKDDrfWANYFKGMITYLREKYDNINHGFNLYI---KANLPSGSGLSSSAAIEMLMGiiLKDEFNLDVDRIVLAKMGQRT 161
Cdd:PLN02865 105 EESN--WGDYARGAVYALQSRGHALSQGITGYIsgsEGLDSSGLSSSAAVGVAYLLA--LENANNLTVSPEDNIELDRLI 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 162 ENEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGE------YEIIIMATNKPHTLAD-SAYNDRVRECHDA 234
Cdd:PLN02865 181 ENEYLGLRNGILDQSAILLSRYGCLTFMDCKTLDHKLVSLQFQQpggekpFKILLAFSGLRHALTNkPGYNLRVSECQEA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 235 VKKLqqkldIKALGE------LDNDTFDEYSYL--IDNETELKRARHAVSENQRTLRATKAMKDGDLEKLGRLIDASHVS 306
Cdd:PLN02865 261 ARFL-----LEASGNdeleplLCNVEPEVYEAHkcKLEAVLARRAEHYFSENMRVIKGVEAWASGNLEEFGKLISASGLS 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 307 LHYDYEVTGKELDTLAEASWKQPGVLGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIYR 366
Cdd:PLN02865 336 SIENYECGCEPLIQLYEILLKAPGVYGARFSGAGFRGCCVAFVDAEMAEEAASFVRDEYE 395
|
|
| PTZ00290 |
PTZ00290 |
galactokinase; Provisional |
23-383 |
1.26e-33 |
|
galactokinase; Provisional
Pssm-ID: 240347 [Multi-domain] Cd Length: 468 Bit Score: 130.33 E-value: 1.26e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 23 FSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGpR----EDKKVRlFSGNVDGdivEFDIDDTTVEKDDRFWANYFKGM 98
Cdd:PTZ00290 41 FAPGRVNFIGEHVDYMGGYVCPAAVLEGCHILVG-RvkhfCDHKLR-FATETDE---HFVLDHLGGAKHNKAWTTFVRGA 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 99 ITyLRekydnINHgFNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDV----------------------------- 149
Cdd:PTZ00290 116 AT-LR-----LNR-LGVAIDAPSLQGVCMVVHGTLPMGAGMSASASFGVALlnaintvvtrrykgcptspgrrysilppm 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 150 ---DRIVLAKMGQRTENEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLA--LGEYE--IIIMATNKPHTLADS 222
Cdd:PTZ00290 189 skeELIELAKQARRIETEFCGVNVGIMDQFISAFAEEDKFMFLDCKSLTFESHDMTplLGDGAcfLLIDSMIKHDLLGGT 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 223 A--YNDRVRECHDAVKKL-QQKLDIKA--LGELDNDTfDEYSYLIDNET------------ELKRARHAVSENQRTLR-- 283
Cdd:PTZ00290 269 AgmYNTVRSDQEGAQKKIgKHRYRGKPftFSDLVRNP-KKYTFDGDVVAfmesckplmtpgEFERGTYNIMEQIRTLEfi 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 284 -----ATKAMKDGDLEKLGRLIDASHVSLHYDYEVTGKELDTLAEASWKQPGVLGARMIGGGFGGSAIAIVKKSEAENFK 358
Cdd:PTZ00290 348 klndpELPLSREERFRKAGEILNAGHQGMRDLMKITTPELDFIHELINEEKGVAGGRMMGGGFGGCIILLLKKNAVDRVV 427
|
410 420
....*....|....*....|....*
gi 327183963 359 KNVGDIYRDKIGYDASFYDAEIVDG 383
Cdd:PTZ00290 428 AHVREKFKARFGVENDVYPVVAGDG 452
|
|
| PLN02521 |
PLN02521 |
galactokinase |
6-365 |
8.66e-32 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 125.59 E-value: 8.66e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 6 LLTEYEKTFGEKgQDVFF-SPGRINVIGEHTDYNGGHVFPAAISLG-VYGVYGPREDKKVRLfsGNVDGD--IVEFDID- 80
Cdd:PLN02521 35 LKAAFVEVYGAK-PDLFArSPGRVNLIGEHIDYEGYSVLPMAIRQDtIVAIRRAEGSKKLRI--ANVNDKytTCTFPADp 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 81 DTTVEKDDRFWANYF----KGMITYLREKYDNINH--GFNLYIKANLPSGSGLSSSAAIEMLMGIILKDEFNLDVDRIVL 154
Cdd:PLN02521 112 DQEVDLANHKWGNYFicgyKGVFEFLKSKGVDVGPpvGLDVVVDGTVPTGSGLSSSAALVCSAAIAIMAALGLNFTKKEV 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 155 AKMGQRTEnEFVGLNSGIMDQFACIMGKKDSAIFLDCNTLKYEYMPLALGEYEII---IMATNKPHTlADSAYNDRVREC 231
Cdd:PLN02521 192 AQFTCKCE-RHIGTQSGGMDQAISIMAQQGVAKLIDFNPVRATDVQLPAGGTFVIansLAESNKAVT-AATNYNNRVVEC 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 232 H---------------DAVKKLQQKLDIKAL-GELDNDT------------FDEYSYLIDNETEL--------------- 268
Cdd:PLN02521 270 RlaaivlavklgmsaeEAISKVKTLSDVEGLcVSFAGSHgssdpavavkelLHEGPYTAEEIEEIlgesltsifknspts 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 269 -------------KRARHAVSENQRTL--RATKAMKDGD---LEKLGRLIDASHVSLHYDYEVTGKELDTLAEASwKQPG 330
Cdd:PLN02521 350 lavlkaakhfklhQRAVHVYSEAKRVHafRDTVSSSLSEeekLKKLGDLMNESHYSCSVLYECSCPELEELVKVC-RDNG 428
|
410 420 430
....*....|....*....|....*....|....*
gi 327183963 331 VLGARMIGGGFGGSAIAIVKKSEAENFKKNVGDIY 365
Cdd:PLN02521 429 ALGARLTGAGWGGCAVALVKEAIVPQFILALKEKF 463
|
|
| GalKase_gal_bdg |
pfam10509 |
Galactokinase galactose-binding signature; This is the highly conserved galactokinase ... |
8-57 |
4.58e-21 |
|
Galactokinase galactose-binding signature; This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Pssm-ID: 463125 [Multi-domain] Cd Length: 50 Bit Score: 85.20 E-value: 4.58e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 327183963 8 TEYEKTFGEKGQDVFFSPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGP 57
Cdd:pfam10509 1 EAFEELFGKEPVGVASAPGRVNLIGEHTDYNGGFVLPAAINLDTYVAVSP 50
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
24-349 |
2.58e-12 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 66.40 E-value: 2.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 24 SPGRINVIGEHTDYNGGHVFPAAISLGVYGVYGPREDKKVRLFSgnvDGDIVEFDIDDTTvekDDRFwaNYFKGMITYLR 103
Cdd:COG1577 1 APGKLILFGEHAVVYGQPAIAVAVDRRATVTVEPSDDDKLRIES---PDLGGTLDLDPLA---DAAL--RYIKAAIEAAL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 104 EKYDNINHGFNLYIKANlpsgsglsssaaIEMLMG----------II--LKDEFNLDVDRIVLAKMGQRTENEFVGLNSG 171
Cdd:COG1577 73 EYLGLPLKGFDIEIDSE------------IPRKRGlgssaavavaVIraLAAFYGVELSKEELFKLALEAEKIVHGNPSG 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 172 iMDQFACIMGKkdsAIFLDCNTlKYEYMPLALGEYeIIImatnkphtladsAYNDRVRECHDAVKKLQQKLDikALGELD 251
Cdd:COG1577 141 -LDTAASTYGG---PIYYQRGD-RAEPLELPKNLP-LVV------------GDTGVPASTKELVAKVRKLKE--RNPELY 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 252 NDTFDEYSYLidnetelkrarhavsenqrTLRATKAMKDGDLEKLGRLIDASHVSLhYDYEVTGKELDTLAEASwKQPGV 331
Cdd:COG1577 201 EAFLEEIGDL-------------------VEEAIEALEEGDLEALGELMNENHGLL-RALGVSTPELDRLVEAA-RKAGA 259
|
330
....*....|....*...
gi 327183963 332 LGARMIGGGFGGSAIAIV 349
Cdd:COG1577 260 LGAKLTGAGGGGCVIALA 277
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
284-367 |
4.17e-07 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 47.46 E-value: 4.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 284 ATKAMKDGDLEKLGRLIDASHVSL--HYDYEVTGKELDTLAEASwKQPGvLGARMIGGGFGGSAIAIVK-KSEAENFKKN 360
Cdd:pfam08544 1 LLEALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEAL-LELG-LGAKLSGSGGGPTVFALFKdEDDAEEVARA 78
|
....*..
gi 327183963 361 VGDIYRD 367
Cdd:pfam08544 79 LREAGKK 85
|
|
| PTZ00298 |
PTZ00298 |
mevalonate kinase; Provisional |
268-353 |
1.44e-05 |
|
mevalonate kinase; Provisional
Pssm-ID: 240351 [Multi-domain] Cd Length: 328 Bit Score: 46.38 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327183963 268 LKRARHAVSEnqrtlrATKAMKDGDLEKLGRLIDASHvSLHYDYEVTGKELDTLAEASwKQPGVLGARMIGGGFGGSAIA 347
Cdd:PTZ00298 220 LENYNACVSE------AKEALQKGNLFRVGELMNANH-DLCQKLTVSCRELDSIVQTC-RTYGALGAKMSGTGRGGLVVA 291
|
....*.
gi 327183963 348 IVKKSE 353
Cdd:PTZ00298 292 LAASED 297
|
|
| |
