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Conserved domains on  [gi|317457033|gb|ADV29598|]
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At5g37260-like protein, partial [Solanum habrochaites]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 10446569)

SANT/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor

CATH:  1.20.58.1880
Gene Ontology:  GO:0003677|GO:0006355|GO:0003700
PubMed:  8882580
SCOP:  4000317

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 40-83 6.04e-14

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 65.60  E-value: 6.04e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 317457033   40 RERWSEEEHKKFLEALKLHGRAWRRIEEHVGTKTAVQIRSHAQK 83
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
 
Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 40-83 6.04e-14

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 65.60  E-value: 6.04e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 317457033   40 RERWSEEEHKKFLEALKLHGRAWRRIEEHVGTKTAVQIRSHAQK 83
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
myb_SHAQKYF TIGR01557
myb-like DNA-binding domain, SHAQKYF class; This model describes a DNA-binding domain ...
 38-88 2.48e-13

myb-like DNA-binding domain, SHAQKYF class; This model describes a DNA-binding domain restricted to (but common in) plant proteins, many of which also contain a response regulator domain. The domain appears related to the Myb-like DNA-binding domain described by pfam00249. It is distinguished in part by a well-conserved motif SH[AL]QKY[RF] at the C-terminal end of the motif.


Pssm-ID: 130620 [Multi-domain]  Cd Length: 57  Bit Score: 64.35  E-value: 2.48e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 317457033   38 KQRERWSEEEHKKFLEAL-KLHGRAW---RRI-EEHVGTK-TAVQIRSHAQKFFSKV 88
Cdd:TIGR01557   1 KPRVVWTEDLHDRFLQAVqKLGGPDWatpKRIlELMVVDGlTRDQVASHLQKYRLKQ 57
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
40-87 5.93e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 57.23  E-value: 5.93e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 317457033    40 RERWSEEEHKKFLEALKLHG-RAWRRIEEHVGTKTAVQIRSHAQKFFSK 87
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 42-85 3.96e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 54.89  E-value: 3.96e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 317457033  42 RWSEEEHKKFLEALKLHG-RAWRRIEEHVGTKTAVQIRSHAQKFF 85
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 40-83 6.04e-14

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 65.60  E-value: 6.04e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 317457033   40 RERWSEEEHKKFLEALKLHGRAWRRIEEHVGTKTAVQIRSHAQK 83
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
myb_SHAQKYF TIGR01557
myb-like DNA-binding domain, SHAQKYF class; This model describes a DNA-binding domain ...
 38-88 2.48e-13

myb-like DNA-binding domain, SHAQKYF class; This model describes a DNA-binding domain restricted to (but common in) plant proteins, many of which also contain a response regulator domain. The domain appears related to the Myb-like DNA-binding domain described by pfam00249. It is distinguished in part by a well-conserved motif SH[AL]QKY[RF] at the C-terminal end of the motif.


Pssm-ID: 130620 [Multi-domain]  Cd Length: 57  Bit Score: 64.35  E-value: 2.48e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 317457033   38 KQRERWSEEEHKKFLEAL-KLHGRAW---RRI-EEHVGTK-TAVQIRSHAQKFFSKV 88
Cdd:TIGR01557   1 KPRVVWTEDLHDRFLQAVqKLGGPDWatpKRIlELMVVDGlTRDQVASHLQKYRLKQ 57
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
40-87 5.93e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 57.23  E-value: 5.93e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 317457033    40 RERWSEEEHKKFLEALKLHG-RAWRRIEEHVGTKTAVQIRSHAQKFFSK 87
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 42-85 3.96e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 54.89  E-value: 3.96e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 317457033  42 RWSEEEHKKFLEALKLHG-RAWRRIEEHVGTKTAVQIRSHAQKFF 85
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT_MTA3_like cd11661
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ...
 43-68 7.38e-03

Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.


Pssm-ID: 212559 [Multi-domain]  Cd Length: 46  Bit Score: 34.51  E-value: 7.38e-03
                         10        20
                 ....*....|....*....|....*.
gi 317457033  43 WSEEEHKKFLEALKLHGRAWRRIEEH 68
Cdd:cd11661    2 WSESEAKLFEEGLRKYGKDFHDIRQD 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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