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Conserved domains on  [gi|315418079|gb|ADU14719|]
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methyl-accepting chemotaxis sensory transducer [Asticcacaulis excentricus CB 48]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
34-577 5.08e-55

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 194.85  E-value: 5.08e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  34 ILALVAAFAIIASAITGLGLATIGDYNKILASYGNANQNAYNGEKLNRLVTLVVMESRGVYMAESTEKAKKFADGVDKGL 113
Cdd:COG0840    3 ILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 114 DDIQALLTSWKATLEPNEL-PAFAAVEAKAQQFITFRREIARVGRDIAPEEANALGNNEANRANRSGFQKDIDAMVTAIR 192
Cdd:COG0840   83 ALLLALLLLLLALLALALAaLALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 193 ADLEKSQAEVAAYSQTRSTLFLLMAVTGILALLAVSLWVAIKVISRPIQNIDRSVTRISEGAYDTPIPEHTaKDEIGSLW 272
Cdd:COG0840  163 LAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDS-KDEIGQLA 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 273 RSIRVLRDRaaeaeqlkveqqmaekrayqelmaernriaaefekhMGELATRFISSSRTVAEAARGLNETAEDashraas 352
Cdd:COG0840  242 DAFNRMIEN------------------------------------LRELVGQVRESAEQVASASEELAASAEE------- 278

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 353 VSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKK---------------------TEEAIQTLST 411
Cdd:COG0840  279 LAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEggevveeavegieeiresveeTAETIEELGE 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 412 AAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTVGSID 491
Cdd:COG0840  359 SSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAME 438

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 492 AIVRTIETIGGLTG-------SIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSSELE 564
Cdd:COG0840  439 EGSEEVEEGVELVEeagealeEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELA 518

                        570
                 ....*....|...
gi 315418079 565 ERSADLQGEVVAF 577
Cdd:COG0840  519 ELAEELQELVSRF 531
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
34-577 5.08e-55

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 194.85  E-value: 5.08e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  34 ILALVAAFAIIASAITGLGLATIGDYNKILASYGNANQNAYNGEKLNRLVTLVVMESRGVYMAESTEKAKKFADGVDKGL 113
Cdd:COG0840    3 ILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 114 DDIQALLTSWKATLEPNEL-PAFAAVEAKAQQFITFRREIARVGRDIAPEEANALGNNEANRANRSGFQKDIDAMVTAIR 192
Cdd:COG0840   83 ALLLALLLLLLALLALALAaLALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 193 ADLEKSQAEVAAYSQTRSTLFLLMAVTGILALLAVSLWVAIKVISRPIQNIDRSVTRISEGAYDTPIPEHTaKDEIGSLW 272
Cdd:COG0840  163 LAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDS-KDEIGQLA 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 273 RSIRVLRDRaaeaeqlkveqqmaekrayqelmaernriaaefekhMGELATRFISSSRTVAEAARGLNETAEDashraas 352
Cdd:COG0840  242 DAFNRMIEN------------------------------------LRELVGQVRESAEQVASASEELAASAEE------- 278

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 353 VSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKK---------------------TEEAIQTLST 411
Cdd:COG0840  279 LAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEggevveeavegieeiresveeTAETIEELGE 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 412 AAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTVGSID 491
Cdd:COG0840  359 SSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAME 438

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 492 AIVRTIETIGGLTG-------SIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSSELE 564
Cdd:COG0840  439 EGSEEVEEGVELVEeagealeEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELA 518

                        570
                 ....*....|...
gi 315418079 565 ERSADLQGEVVAF 577
Cdd:COG0840  519 ELAEELQELVSRF 531
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 331-571 1.11e-38

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 142.81  E-value: 1.11e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079   331 TVAEAARGLNETAEDASHRAASVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAV-------EEAKKTE 403
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAItamdqirEVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079   404 EAIQTLSTAAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSAT 483
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079   484 AVTVGSIDAIVRTIETIGGLTG-------SIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQL 556
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEetgdaleEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250
                   ....*....|....*
gi 315418079   557 LGLSSELEERSADLQ 571
Cdd:smart00283 241 SAAAEELSGLAEELD 255
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 352-536 3.77e-35

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 131.21  E-value: 3.77e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 352 SVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKKTEEAIQTLSTAAQQIGEVINLIQAIAAQTN 431
Cdd:cd11386    2 ELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQTN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 432 LLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTVGSIDA-------IVRTIETIGGLT 504
Cdd:cd11386   82 LLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEEtseeveeGVELVEETGRAF 161

                        170       180       190
                 ....*....|....*....|....*....|..
gi 315418079 505 GSIAASVEQQGAATNEIAANTNRAATGTRDVT 536
Cdd:cd11386  162 EEIVASVEEVADGIQEISAATQEQSASTQEIA 193
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
114-577 4.09e-30

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 124.41  E-value: 4.09e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 114 DDIQALLTSWKATLEPNE--LPAFAAVEAKAQQFITFRREI----ARVGRDIApEEANALGNNEAN-------RANRSGF 180
Cdd:PRK09793  81 DDIKTLMTTARASLTQSTtlFKSFMAMTAGNEHVRALQKETeksfARWHNDLE-HQATWLESNQLSdfltapvQGSQNAF 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 181 QKDIDAMVTAIRADLEKSQAEVAAYSQTRSTLFLLMAVTGILaLLAVSLWVAIKVISRPIQNIDRSVTRISEGAYDTPIP 260
Cdd:PRK09793 160 DVNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAI-YISSALWWTRKMIVQPLAIIGSHFDSIAAGNLARPIA 238

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 261 EHtAKDEIGSLWRSIRvlrdraaeAEQLKVEQQMAEKRAyqelmaernriaAEFEKHMGelatrfisssrtVAEAARGLN 340
Cdd:PRK09793 239 VY-GRNEITAIFASLK--------TMQQALRGTVSDVRK------------GSQEMHIG------------IAEIVAGNN 285

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 341 ETAEDASHRAASVSQAAidaannvqnvaAATEELSASVGEINHQVVRTAEVTQSAVEEAKK-------TEEAIQTLSTAA 413
Cdd:PRK09793 286 DLSSRTEQQAASLAQTA-----------ASMEQLTATVGQNADNARQASELAKNAATTAQAggvqvstMTHTMQEIATSS 354

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 414 QQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEiqSATAVTVGSidai 493
Cdd:PRK09793 355 QKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKGLIEE--SVNRVQQGS---- 428

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 494 vRTIETIGGLTGSIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSSELEERSADLQGE 573
Cdd:PRK09793 429 -KLVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSR 507


                 ....
gi 315418079 574 VVAF 577
Cdd:PRK09793 508 VAVF 511
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 388-544 2.90e-23

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 96.73  E-value: 2.90e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  388 TAEVTQSAVEEAKKTEEAIqtlSTAAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAK 467
Cdd:pfam00015  10 EAQDGGKEVANVVGQMEQI---AQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQ 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  468 ATDDIRAKISEIQSATAVTVGSIDAIVRTIETIGGLTGS-------IAASVEQQGAATNEIAANTNRAATGTRDVTGHIS 540
Cdd:pfam00015  87 AAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVEStgealkeIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVA 166


                  ....
gi 315418079  541 GVDQ 544
Cdd:pfam00015 167 RMDQ 170
Mtu_fam_mce TIGR00996
virulence factor Mce family protein; Members of this paralogous family are found as six tandem ...
 410-570 5.22e-03

virulence factor Mce family protein; Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis]


Pssm-ID: 273384 [Multi-domain]  Cd Length: 291  Bit Score: 39.19  E-value: 5.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  410 STAAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKG--FAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTV 487
Cdd:TIGR00996 126 TTVPLELDDLLGSLTRLLNGLDPEKLNAILNALAQALAGQGpqLRNLLDGLAQLTAALNERDGDIGELIRNLNRVLDVLA 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  488 GSIDAIVRTIETIGGLTGSIAasveQQGAATNEIAANTNRAATGTRDVtghisgVDQAAQMTGHAAQQLLGLSSELEERS 567
Cdd:TIGR00996 206 DRSDQLDRLLDNLPTLIATLA----DRSDALDDALAALSAASAQVRDL------LAENRPNLGQALANLAPVLTLLVDYS 275


                  ...
gi 315418079  568 ADL 570
Cdd:TIGR00996 276 PEL 278
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
34-577 5.08e-55

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 194.85  E-value: 5.08e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  34 ILALVAAFAIIASAITGLGLATIGDYNKILASYGNANQNAYNGEKLNRLVTLVVMESRGVYMAESTEKAKKFADGVDKGL 113
Cdd:COG0840    3 ILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 114 DDIQALLTSWKATLEPNEL-PAFAAVEAKAQQFITFRREIARVGRDIAPEEANALGNNEANRANRSGFQKDIDAMVTAIR 192
Cdd:COG0840   83 ALLLALLLLLLALLALALAaLALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 193 ADLEKSQAEVAAYSQTRSTLFLLMAVTGILALLAVSLWVAIKVISRPIQNIDRSVTRISEGAYDTPIPEHTaKDEIGSLW 272
Cdd:COG0840  163 LAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDS-KDEIGQLA 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 273 RSIRVLRDRaaeaeqlkveqqmaekrayqelmaernriaaefekhMGELATRFISSSRTVAEAARGLNETAEDashraas 352
Cdd:COG0840  242 DAFNRMIEN------------------------------------LRELVGQVRESAEQVASASEELAASAEE------- 278

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 353 VSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKK---------------------TEEAIQTLST 411
Cdd:COG0840  279 LAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEggevveeavegieeiresveeTAETIEELGE 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 412 AAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTVGSID 491
Cdd:COG0840  359 SSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAME 438

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 492 AIVRTIETIGGLTG-------SIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSSELE 564
Cdd:COG0840  439 EGSEEVEEGVELVEeagealeEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELA 518

                        570
                 ....*....|...
gi 315418079 565 ERSADLQGEVVAF 577
Cdd:COG0840  519 ELAEELQELVSRF 531
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 331-571 1.11e-38

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 142.81  E-value: 1.11e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079   331 TVAEAARGLNETAEDASHRAASVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAV-------EEAKKTE 403
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAItamdqirEVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079   404 EAIQTLSTAAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSAT 483
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079   484 AVTVGSIDAIVRTIETIGGLTG-------SIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQL 556
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEetgdaleEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250
                   ....*....|....*
gi 315418079   557 LGLSSELEERSADLQ 571
Cdd:smart00283 241 SAAAEELSGLAEELD 255
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 352-536 3.77e-35

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 131.21  E-value: 3.77e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 352 SVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKKTEEAIQTLSTAAQQIGEVINLIQAIAAQTN 431
Cdd:cd11386    2 ELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQTN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 432 LLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTVGSIDA-------IVRTIETIGGLT 504
Cdd:cd11386   82 LLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEEtseeveeGVELVEETGRAF 161

                        170       180       190
                 ....*....|....*....|....*....|..
gi 315418079 505 GSIAASVEQQGAATNEIAANTNRAATGTRDVT 536
Cdd:cd11386  162 EEIVASVEEVADGIQEISAATQEQSASTQEIA 193
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
114-577 4.09e-30

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 124.41  E-value: 4.09e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 114 DDIQALLTSWKATLEPNE--LPAFAAVEAKAQQFITFRREI----ARVGRDIApEEANALGNNEAN-------RANRSGF 180
Cdd:PRK09793  81 DDIKTLMTTARASLTQSTtlFKSFMAMTAGNEHVRALQKETeksfARWHNDLE-HQATWLESNQLSdfltapvQGSQNAF 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 181 QKDIDAMVTAIRADLEKSQAEVAAYSQTRSTLFLLMAVTGILaLLAVSLWVAIKVISRPIQNIDRSVTRISEGAYDTPIP 260
Cdd:PRK09793 160 DVNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAI-YISSALWWTRKMIVQPLAIIGSHFDSIAAGNLARPIA 238

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 261 EHtAKDEIGSLWRSIRvlrdraaeAEQLKVEQQMAEKRAyqelmaernriaAEFEKHMGelatrfisssrtVAEAARGLN 340
Cdd:PRK09793 239 VY-GRNEITAIFASLK--------TMQQALRGTVSDVRK------------GSQEMHIG------------IAEIVAGNN 285

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 341 ETAEDASHRAASVSQAAidaannvqnvaAATEELSASVGEINHQVVRTAEVTQSAVEEAKK-------TEEAIQTLSTAA 413
Cdd:PRK09793 286 DLSSRTEQQAASLAQTA-----------ASMEQLTATVGQNADNARQASELAKNAATTAQAggvqvstMTHTMQEIATSS 354

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 414 QQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEiqSATAVTVGSidai 493
Cdd:PRK09793 355 QKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKGLIEE--SVNRVQQGS---- 428

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 494 vRTIETIGGLTGSIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSSELEERSADLQGE 573
Cdd:PRK09793 429 -KLVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSR 507


                 ....
gi 315418079 574 VVAF 577
Cdd:PRK09793 508 VAVF 511
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
309-577 2.33e-26

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 113.13  E-value: 2.33e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 309 RIAAEFEKHMGELAT--RFISSS--RTVAEAARGLNETAEDASHRAA---SVSQAAIDAANNVQNVAAATEELSASVGEI 381
Cdd:PRK15041 240 PIEVDGSNEMGQLAEslRHMQGElmRTVGDVRNGANAIYSGASEIATgnnDLSSRTEQQAASLEETAASMEQLTATVKQN 319

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 382 NHQVVRTAEVTQSAVEEAKK----TEEAIQTL---STAAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVV 454
Cdd:PRK15041 320 AENARQASHLALSASETAQRggkvVDNVVQTMrdiSTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV 399

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 455 ASEVKQLAQQTAKATDDIRAKISEiqsatavTVGSIDAIVRTIETIGGLTGSIAASVEQQGAATNEIAANTNRAATGTRD 534
Cdd:PRK15041 400 AGEVRNLAQRSAQAAREIKSLIED-------SVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQ 472

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 315418079 535 VTGHISGVDQAAQMTGHAAQQLLGLSSELEERSADLQGEVVAF 577
Cdd:PRK15041 473 VGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTEAVAVF 515
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 388-544 2.90e-23

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 96.73  E-value: 2.90e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  388 TAEVTQSAVEEAKKTEEAIqtlSTAAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAK 467
Cdd:pfam00015  10 EAQDGGKEVANVVGQMEQI---AQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQ 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  468 ATDDIRAKISEIQSATAVTVGSIDAIVRTIETIGGLTGS-------IAASVEQQGAATNEIAANTNRAATGTRDVTGHIS 540
Cdd:pfam00015  87 AAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVEStgealkeIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVA 166


                  ....
gi 315418079  541 GVDQ 544
Cdd:pfam00015 167 RMDQ 170
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 318-577 8.67e-23

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 102.39  E-value: 8.67e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 318 MGELATRFISSSR----TVAEAARGLNETAEDASHRAA---SVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAE 390
Cdd:PRK15048 247 MGDLAQSVSHMQRsltdTVTHVREGSDAIYAGTREIAAgntDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQ 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 391 VTQSAVEEAKKTEEAI-------QTLSTAAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQ 463
Cdd:PRK15048 327 LAQSASDTAQHGGKVVdgvvktmHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAS 406

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 464 QTAKATDDIRAKISEiqSATAVTVGSIdaivrTIETIGGLTGSIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVD 543
Cdd:PRK15048 407 RSAQAAKEIKALIED--SVSRVDTGSV-----LVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMD 479

                        250       260       270
                 ....*....|....*....|....*....|....
gi 315418079 544 QAAQMTGHAAQQLLGLSSELEERSADLQGEVVAF 577
Cdd:PRK15048 480 RVTQQNASLVQESAAAAAALEEQASRLTQAVSAF 513
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
21-584 1.26e-07

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 54.73  E-value: 1.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  21 TEFGVKKMSIKFKILALVAAFAIIASAITGLGLATIGDYNKILASYGNANQNAYNGEKLNRLVTLVVMESRGVYMAESTE 100
Cdd:COG2770   22 AGALLVLALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 101 KAKKFADGVDKGLDDIQALLTSWKATLEPNELPAFAAVEAKAQQFITFRREIARVGRDIAPEEANALGNNEANRANRSGF 180
Cdd:COG2770  102 LLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAA 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 181 QKDIDAMVTAIRADLEKSQAEVAAYSQTRSTLFLLMAVTGILALLAVSLWVAiKVISRPIQNIDRSVTRISEGAYDTPIP 260
Cdd:COG2770  182 AIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLA-RRITRPLRRLAEAARRIAAGDLDVRIP 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 261 EHTaKDEIGSLWRSIRVLRDRAAEAEQLKVEQQMAEKRAYQELMAERNRIAAEFEKHMGELATRFISSSRTVAEAARGLN 340
Cdd:COG2770  261 VSR-KDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLA 339

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 341 ETAEDASHRAASVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKKTEEAIQTLSTAAQQIGEVI 420
Cdd:COG2770  340 LLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLAL 419

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 421 NLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTVGSIDAIVRTIETI 500
Cdd:COG2770  420 ALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAG 499

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 501 GGLTGSIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSSELEERSADLQGEVVAFVQR 580
Cdd:COG2770  500 AAAEELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALLALLLALAAVEAAALLLAALLLAAVAAL 579


                 ....
gi 315418079 581 LRAA 584
Cdd:COG2770  580 LELA 583
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 206-293 1.03e-06

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 51.12  E-value: 1.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 206 SQTRSTLFLLMAVTGILALLAvSLWVAIKV---ISRPIQNIDRSVTRISEGAYDTPIPEhTAKDEIGSLWRSIRVLRDRA 282
Cdd:COG5000    1 SGLQILFLLLLLLIALLLLLL-ALWLALLLarrLTRPLRRLAEATRAVAAGDLSVRLPV-TGDDEIGELARAFNRMTDQL 78

                         90
                 ....*....|.
gi 315418079 283 AEAEQLKVEQQ 293
Cdd:COG5000   79 KEQREELEERR 89
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 265-572 2.02e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.62  E-value: 2.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 265 KDEIGSLWRSIRVLRDRAAEAEQLKVEQQMAEKRA-YQELMAERNRIAAEFEkhmgELATRFISSSRTVAEAARGLNETA 343
Cdd:COG1196  219 KEELKELEAELLLLKLRELEAELEELEAELEELEAeLEELEAELAELEAELE----ELRLELEELELELEEAQAEEYELL 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 344 EDASHRAASVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKKTEEAIQTLSTAAQQIGEVinLI 423
Cdd:COG1196  295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA--EA 372

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 424 QAIAAQTNLLALNATIESARAGEagkgfAVVASEVKQLAQQTAKATDDIRAKISEIQSATAvtvgsidAIVRTIETIGGL 503
Cdd:COG1196  373 ELAEAEEELEELAEELLEALRAA-----AELAAQLEELEEAEEALLERLERLEEELEELEE-------ALAELEEEEEEE 440

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 315418079 504 TGSIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSSELEERSADLQG 572
Cdd:COG1196  441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 237-281 5.22e-04

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 37.81  E-value: 5.22e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 315418079 237 SRPIQNIDRSVTRISEGAYDTPIPEHTaKDEIGSLWRSIRVLRDR 281
Cdd:cd06225    1 TRPLRRLTEAARRIAEGDLDVRVPVRS-KDEIGELARAFNQMAER 44
PRK11466 PRK11466
hybrid sensory histidine kinase TorS; Provisional
 180-316 1.13e-03

hybrid sensory histidine kinase TorS; Provisional


Pssm-ID: 236914 [Multi-domain]  Cd Length: 914  Bit Score: 42.20  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 180 FQKDIDAMVTAIRADLEKSQAEVAAYSQTRSTLFLLMAVTGILALLAVSLWVAIKVISRPIQNIDRSVTRISEGAYDTPI 259
Cdd:PRK11466 300 FSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLLLLGMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPF 379

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 315418079 260 PEHTAKDEIGSLWR-------SIRVL-RDRAAEAEQlkVEQQMAEkraYQELMAERNRIAAEFEK 316
Cdd:PRK11466 380 PETAGVRELDTIGRlmdafrsNVHALnRHREQLAAQ--VKARTAE---LQELVIEHRQARAEAEK 439
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 261-584 1.81e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 1.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 261 EHTAKDEIGSLWRSIRVLRDRAAEA---------EQLKVEQQMAEKrayQELMAERNRIAAEFEKHMGELATRFISSSRT 331
Cdd:COG1196  290 EYELLAELARLEQDIARLEERRRELeerleeleeELAELEEELEEL---EEELEELEEELEEAEEELEEAEAELAEAEEA 366

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 332 VAEAARGLNETAEDASHRAASVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKKTEEAIQTLST 411
Cdd:COG1196  367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 412 AAQQIG----EVINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTV 487
Cdd:COG1196  447 AAEEEAeleeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 488 GSIDAIVRTIET------IGGLTGSIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSS 561
Cdd:COG1196  527 AVLIGVEAAYEAaleaalAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS 606

                        330       340
                 ....*....|....*....|...
gi 315418079 562 ELEERSADLQGEVVAFVQRLRAA 584
Cdd:COG1196  607 DLREADARYYVLGDTLLGRTLVA 629
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 261-584 1.85e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 1.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 261 EHTAKDEIGSLWRSIRVLRDRAAEAEQLKVEQQMAEKRAyQELMAERNRIAAEFEKHMGELATRFISSSRTVAEAARGLN 340
Cdd:COG1196  374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL-LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 341 ETAEDASHRAASVSQAAIDAANNVQNVAAATEELS--ASVGEINHQVVRTAEVTQSAVEEAKKTEEAIQTLSTAAQQIGE 418
Cdd:COG1196  453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAeaAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 419 VINLIQAIAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQTAKATDdiRAKISEIQSATAVTVGSIDAIVRTIE 498
Cdd:COG1196  533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRA--RAALAAALARGAIGAAVDLVASDLRE 610

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 499 TIGGLTGSIAASVEQQGAATNEIAANTNRAATGTR--DVTGHISGVDQAAQMTGHAAQQLLGLSSELEERSADLQGEVVA 576
Cdd:COG1196  611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRlrEVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690


                 ....*...
gi 315418079 577 FVQRLRAA 584
Cdd:COG1196  691 EELELEEA 698
PRK12472 PRK12472
hypothetical protein; Provisional
 333-464 3.22e-03

hypothetical protein; Provisional


Pssm-ID: 237110 [Multi-domain]  Cd Length: 508  Bit Score: 40.24  E-value: 3.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 333 AEAARGLNEtAEDASHRAASVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSA-VEEAK-KTEEAIQTLS 410
Cdd:PRK12472 190 ARAETLARE-AEDAARAADEAKTAAAAAAREAAPLKASLRKLERAKARADAELKRADKALAAAkTDEAKaRAEERQQKAA 268

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 315418079 411 TAAQQIGEVINLIQAiAAQTNLLALNATIESARAGEAGKGFAVVASEVKQLAQQ 464
Cdd:PRK12472 269 QQAAEAATQLDTAKA-DAEAKRAAAAATKEAAKAAAAKKAETAKAATDAKLALE 321
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
263-583 3.36e-03

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 40.39  E-value: 3.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 263 TAKDEIGSLWRSIRVLRDRAAEAEQLKVEQQMAEKRAYQELMAERNRIAAEFEKHMGELATRFISSSRTVAEAARGLNET 342
Cdd:COG0840   41 TALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLALLELLL 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 343 AEDASHRAASVSQAAIDAANNVQNVAAATEELSASVGEINHQVVRTAEVTQSAVEEAKKTEEAIQTLSTAAQQIGEVINL 422
Cdd:COG0840  121 AALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILAL 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 423 IQAIAAQTNLLALNATIESARAGEAGKGFAVVAS-EVKQLAQQTAKATDDIRAKISEIQSATavtvgsiDAIVRTIETIG 501
Cdd:COG0840  201 LLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKdEIGQLADAFNRMIENLRELVGQVRESA-------EQVASASEELA 273

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079 502 GLTGSIAASVEQQGAATNEIAANTNRAATGTRDVTGHISGVDQAAQMTGHAAQQLLGLSSELEERSADLQGEVVAFVQRL 581
Cdd:COG0840  274 ASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETI 353


                 ..
gi 315418079 582 RA 583
Cdd:COG0840  354 EE 355
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 309-421 4.57e-03

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 39.19  E-value: 4.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079   309 RIAAEFEKHMGELATRFISSSRTVAEAARGLNETAEDASHRAASVSQAAidaaNNVQNVAAATEELSASVGEINHQVVRT 388
Cdd:smart00283 151 SLIKEIQEETNEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIA----DLVQEIAAATDEQAAGSEEVNAAIDEI 226

                           90       100       110
                   ....*....|....*....|....*....|...
gi 315418079   389 AEVTQSAVEEAKKTEEAIQTLSTAAQQIGEVIN 421
Cdd:smart00283 227 AQVTQETAAMSEEISAAAEELSGLAEELDELVE 259
Mtu_fam_mce TIGR00996
virulence factor Mce family protein; Members of this paralogous family are found as six tandem ...
 410-570 5.22e-03

virulence factor Mce family protein; Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis]


Pssm-ID: 273384 [Multi-domain]  Cd Length: 291  Bit Score: 39.19  E-value: 5.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  410 STAAQQIGEVINLIQAIAAQTNLLALNATIESARAGEAGKG--FAVVASEVKQLAQQTAKATDDIRAKISEIQSATAVTV 487
Cdd:TIGR00996 126 TTVPLELDDLLGSLTRLLNGLDPEKLNAILNALAQALAGQGpqLRNLLDGLAQLTAALNERDGDIGELIRNLNRVLDVLA 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315418079  488 GSIDAIVRTIETIGGLTGSIAasveQQGAATNEIAANTNRAATGTRDVtghisgVDQAAQMTGHAAQQLLGLSSELEERS 567
Cdd:TIGR00996 206 DRSDQLDRLLDNLPTLIATLA----DRSDALDDALAALSAASAQVRDL------LAENRPNLGQALANLAPVLTLLVDYS 275


                  ...
gi 315418079  568 ADL 570
Cdd:TIGR00996 276 PEL 278
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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