|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
1-806 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1429.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 1 MSQVLPVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAA 80
Cdd:PRK05560 2 GDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 81 IYDTLVRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALP 160
Cdd:PRK05560 82 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 161 NLLVNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAK-LSRRGIKEAYATGRGSLKVRA 239
Cdd:PRK05560 162 NLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIiLGRSGIREAYRTGRGSIVMRA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 240 RVRNEDKNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRL 319
Cdd:PRK05560 242 KAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 320 QTSFTVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEA 399
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 400 RAGLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGDQRRTQ 479
Cdd:PRK05560 402 KEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRTE 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 480 ITEFEEGFSLEDLIEDEPMVITLTSQGFVKRTPLEAYRAQGRGGMGAQAGKTKEEDEAISVFVASMHDTLLIFTNRGRVY 559
Cdd:PRK05560 482 IIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVY 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 560 GEKVHELPEASRQARGTHIVSLLPLQEGEEVAALLNVRDLTQEGYFVFATKNGLIKKTEIKEYQNLSSAGLIAINLLEND 639
Cdd:PRK05560 562 RLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGD 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 640 ALVGVAIAQEGDQVMLATQSGQAIRFELSDVRATGRASQGVTGIRFKEGrdDRVVSLVILpKGEESEVLAVGSHGYGKRT 719
Cdd:PRK05560 642 ELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREG--DEVVSMDVV-REDSQEILTVTENGYGKRT 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 720 PISEYPLQGRGGMGVITFNTNEKVGQLAALMRVQGNEDLLVLSRRGNAIRTKVSSIAQYGRATSGVRVMNLSDKDEIASA 799
Cdd:PRK05560 719 PVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDKVVSV 798
|
....*..
gi 290469794 800 FVIAPQD 806
Cdd:PRK05560 799 ARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
2-799 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1365.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 2 SQVLPVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAI 81
Cdd:COG0188 8 ERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHGDSAV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 82 YDTLVRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPN 161
Cdd:COG0188 88 YDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPARFPN 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 162 LLVNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAK-LSRRGIKEAYATGRGSLKVRAR 240
Cdd:COG0188 168 LLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIiVGREGIREAYETGRGSIRVRAK 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 241 VR-NEDKNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRL 319
Cdd:COG0188 248 AEiEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQLYKHTQL 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 320 QTSFTVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEA 399
Cdd:COG0188 328 QTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRASKDPDEA 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 400 RAGLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGDQRRTQ 479
Cdd:COG0188 408 KEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTE 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 480 ITEFEEGFSLEDLIEDEPMVITLTSQGFVKRTPLEAYRAQGRGGMGAQAGKTKEEDEAISVFVASMHDTLLIFTNRGRVY 559
Cdd:COG0188 488 IEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVY 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 560 GEKVHELPEASRQARGTHIVSLLPLQEGEEVAALLNVRDLTQEGYFVFATKNGLIKKTEIKEYQNLSSAGLIAINLLEND 639
Cdd:COG0188 568 RLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGD 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 640 ALVGVAIAQEGDQVMLATQSGQAIRFELSDVRATGRASQGVTGIRFKEGrdDRVVSLVILPkgEESEVLAVGSHGYGKRT 719
Cdd:COG0188 648 ELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEG--DEVVGMAVVD--EEDDLLTVTENGYGKRT 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 720 PISEYPLQGRGGMGVITFNTNEKVGQLAALMRVQGNEDLLVLSRRGNAIRTKVSSIAQYGRATSGVRVMNLSDKDEIASA 799
Cdd:COG0188 724 PLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
4-798 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1162.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 4 VLPVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYD 83
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 84 TLVRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLL 163
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 164 VNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAK-LSRRGIKEAYATGRGSLKVRARVR 242
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIiLGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 243 -NEDKNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRLQT 321
Cdd:TIGR01063 241 iEEDSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 322 SFTVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEARA 401
Cdd:TIGR01063 321 SFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAKT 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 402 GLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGDQRRTQIT 481
Cdd:TIGR01063 401 RLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEIV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 482 -EFEEGFSLEDLIEDEPMVITLTSQGFVKRTPLEAYRAQGRGGMGAQAGKTKEEDEAISVFVASMHDTLLIFTNRGRVYG 560
Cdd:TIGR01063 481 yDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYW 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 561 EKVHELPEASRQARGTHIVSLLPLQEGEEVAALLNVRDLTQEGYFVFATKNGLIKKTEIKEYQNLSSAGLIAINLLENDA 640
Cdd:TIGR01063 561 LKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 641 LVGVAIAQEGDQVMLATQSGQAIRFELSDVRATGRASQGVTGIRFKEGrdDRVVSLVILPkgEESEVLAVGSHGYGKRTP 720
Cdd:TIGR01063 641 LISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNE--DFVVSLLVVS--EESYLLIVTENGYGKRTS 716
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 290469794 721 ISEYPLQGRGGMGVITFNTNEKVGQLAALMRVQGNEDLLVLSRRGNAIRTKVSSIAQYGRATSGVRVMNLSDKDEIAS 798
Cdd:TIGR01063 717 IEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLVS 794
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
26-468 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 668.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 26 VDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLVRLAQPWNLRYPLIDGQGNF 105
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 106 GSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLLVNGSAGIAVGMATSLPPHNLGE 185
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 186 VVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAKL-SRRGIKEAYATGRGSLKVRARVRNEDKNGRAMLVFTEIPYQVNKA 264
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIeGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQVNKA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 265 DLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRLQTSFTVNLLAIV-KGEPKVLTLLEL 343
Cdd:cd00187 241 KLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKLNLKEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 344 MRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSqdaAEARAGLMGRF---SLTEVQAQAILDM 420
Cdd:cd00187 321 LQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQADAILDM 397
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 290469794 421 RLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAI 468
Cdd:cd00187 398 RLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
28-465 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 639.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 28 RALPDVRDGLKPVQRRILYGAYQDgVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLVRLAQPWNLRYPLIDGQGNFGS 107
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 108 V-DGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLLVNGSAGIAVGMATSLPPHNLGEV 186
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 187 VDALVLMIDNPEVTLeeVMKVLPGPDFPTGA-KLSRRGIKEAYATGRGSLKVRARVRNEDKNGramLVFTEIPYQVNKAD 265
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGgIIGKGGIKEAYKTGRGKITVRAKVEIEDRKT---IVITELPYGVWTSD 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 266 LIAQIASLVRNKVIDEIAALRDESDRqGMRIAVELKRGANPQVVLNKLYKHSRLQTSFTVNLLAIVKGEPKVLTLLELMR 345
Cdd:pfam00521 235 LIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEILK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 346 HYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEARAGLMGRfsLTEVQAQAILDMRLQRL 425
Cdd:pfam00521 314 EFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE--LSEIQADYLLDMRLRRL 391
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 290469794 426 VGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDEL 465
Cdd:pfam00521 392 TKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
7-458 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 634.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 7 VEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLV 86
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 87 RLAQPWNLRYPLIDGQGNFGSV-DGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLLVN 165
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 166 GSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGaklsrrGIKeayaTGRGSLKVRARVRNED 245
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTG------GEI----VGPGKYVVRGKIEIED 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 246 KNGramLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDES-DRQGMRIAVELKRGANPQVVLNKLYKHSRLQTSFT 324
Cdd:smart00434 231 DNT---IVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTTFS 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 325 VNLLAIV-KGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKAR-ERAHVLEGLLIALDHIDEVIALIRGSQD-AAEARA 401
Cdd:smart00434 308 INMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDlAKEAKE 387
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 290469794 402 GLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLW 458
Cdd:smart00434 388 KLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
6-118 |
6.55e-58 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 214.97 E-value: 6.55e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 6 PVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTL 85
Cdd:NF038098 4 PVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYDTL 83
|
90 100 110
....*....|....*....|....*....|...
gi 290469794 86 VRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRY 118
Cdd:NF038098 84 VRMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
1-806 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1429.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 1 MSQVLPVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAA 80
Cdd:PRK05560 2 GDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 81 IYDTLVRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALP 160
Cdd:PRK05560 82 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 161 NLLVNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAK-LSRRGIKEAYATGRGSLKVRA 239
Cdd:PRK05560 162 NLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIiLGRSGIREAYRTGRGSIVMRA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 240 RVRNEDKNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRL 319
Cdd:PRK05560 242 KAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 320 QTSFTVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEA 399
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 400 RAGLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGDQRRTQ 479
Cdd:PRK05560 402 KEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRTE 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 480 ITEFEEGFSLEDLIEDEPMVITLTSQGFVKRTPLEAYRAQGRGGMGAQAGKTKEEDEAISVFVASMHDTLLIFTNRGRVY 559
Cdd:PRK05560 482 IIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVY 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 560 GEKVHELPEASRQARGTHIVSLLPLQEGEEVAALLNVRDLTQEGYFVFATKNGLIKKTEIKEYQNLSSAGLIAINLLEND 639
Cdd:PRK05560 562 RLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGD 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 640 ALVGVAIAQEGDQVMLATQSGQAIRFELSDVRATGRASQGVTGIRFKEGrdDRVVSLVILpKGEESEVLAVGSHGYGKRT 719
Cdd:PRK05560 642 ELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREG--DEVVSMDVV-REDSQEILTVTENGYGKRT 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 720 PISEYPLQGRGGMGVITFNTNEKVGQLAALMRVQGNEDLLVLSRRGNAIRTKVSSIAQYGRATSGVRVMNLSDKDEIASA 799
Cdd:PRK05560 719 PVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDKVVSV 798
|
....*..
gi 290469794 800 FVIAPQD 806
Cdd:PRK05560 799 ARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
2-799 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1365.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 2 SQVLPVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAI 81
Cdd:COG0188 8 ERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHGDSAV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 82 YDTLVRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPN 161
Cdd:COG0188 88 YDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPARFPN 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 162 LLVNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAK-LSRRGIKEAYATGRGSLKVRAR 240
Cdd:COG0188 168 LLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIiVGREGIREAYETGRGSIRVRAK 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 241 VR-NEDKNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRL 319
Cdd:COG0188 248 AEiEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQLYKHTQL 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 320 QTSFTVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEA 399
Cdd:COG0188 328 QTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRASKDPDEA 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 400 RAGLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGDQRRTQ 479
Cdd:COG0188 408 KEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTE 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 480 ITEFEEGFSLEDLIEDEPMVITLTSQGFVKRTPLEAYRAQGRGGMGAQAGKTKEEDEAISVFVASMHDTLLIFTNRGRVY 559
Cdd:COG0188 488 IEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVY 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 560 GEKVHELPEASRQARGTHIVSLLPLQEGEEVAALLNVRDLTQEGYFVFATKNGLIKKTEIKEYQNLSSAGLIAINLLEND 639
Cdd:COG0188 568 RLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGD 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 640 ALVGVAIAQEGDQVMLATQSGQAIRFELSDVRATGRASQGVTGIRFKEGrdDRVVSLVILPkgEESEVLAVGSHGYGKRT 719
Cdd:COG0188 648 ELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEG--DEVVGMAVVD--EEDDLLTVTENGYGKRT 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 720 PISEYPLQGRGGMGVITFNTNEKVGQLAALMRVQGNEDLLVLSRRGNAIRTKVSSIAQYGRATSGVRVMNLSDKDEIASA 799
Cdd:COG0188 724 PLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
4-798 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1162.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 4 VLPVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYD 83
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 84 TLVRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLL 163
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 164 VNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAK-LSRRGIKEAYATGRGSLKVRARVR 242
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIiLGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 243 -NEDKNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRLQT 321
Cdd:TIGR01063 241 iEEDSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 322 SFTVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEARA 401
Cdd:TIGR01063 321 SFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAKT 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 402 GLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGDQRRTQIT 481
Cdd:TIGR01063 401 RLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEIV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 482 -EFEEGFSLEDLIEDEPMVITLTSQGFVKRTPLEAYRAQGRGGMGAQAGKTKEEDEAISVFVASMHDTLLIFTNRGRVYG 560
Cdd:TIGR01063 481 yDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYW 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 561 EKVHELPEASRQARGTHIVSLLPLQEGEEVAALLNVRDLTQEGYFVFATKNGLIKKTEIKEYQNLSSAGLIAINLLENDA 640
Cdd:TIGR01063 561 LKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 641 LVGVAIAQEGDQVMLATQSGQAIRFELSDVRATGRASQGVTGIRFKEGrdDRVVSLVILPkgEESEVLAVGSHGYGKRTP 720
Cdd:TIGR01063 641 LISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNE--DFVVSLLVVS--EESYLLIVTENGYGKRTS 716
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 290469794 721 ISEYPLQGRGGMGVITFNTNEKVGQLAALMRVQGNEDLLVLSRRGNAIRTKVSSIAQYGRATSGVRVMNLSDKDEIAS 798
Cdd:TIGR01063 717 IEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLVS 794
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-734 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 894.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 1 MSQVLPVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAA 80
Cdd:PRK05561 7 LEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHGDSS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 81 IYDTLVRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALP 160
Cdd:PRK05561 87 IYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPARFP 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 161 NLLVNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAKL--SRRGIKEAYATGRGSLKVR 238
Cdd:PRK05561 167 NLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGEIitGRDGIRKAYETGRGSIRVR 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 239 ARVRNED-KNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQG-MRIAVELK-RGANPQVVLNKLYK 315
Cdd:PRK05561 247 ARWEIEDlAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENpVRIVIEPKsNRVDPEALMNHLFA 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 316 HSRLQTSFTVNLLAI-VKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQ 394
Cdd:PRK05561 327 TTDLESSYRVNMNAIgLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRIIRESD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 395 DaaeARAGLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGD 474
Cdd:PRK05561 407 E---PKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAKKFGD 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 475 QRRTQITE--FEEGFSLEDLIEDEPMVITLTSQGFVKRTpleayraQGRgGMGAQAGKTKEEDEAISVFVASMHDTLLIF 552
Cdd:PRK05561 484 PRRTPIEEaeEAIAIDEEALIPDEPVTVVLSKKGWVRRA-------KGH-SIDASGLSFKEGDSLLFAFEARTTDKLLLF 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 553 TNRGRVYGEKVHELPEASRQarGTHIVSLLPLQEGEEVAALLnvrDLTQEGYFVFATKNGLIKKTEIKEYQNLSSAGLIA 632
Cdd:PRK05561 556 TSTGRVYSLPVHELPSARGD--GEPLTGLVDLAPGEEIVHVL---AFDPDQKLLLASSAGYGFVVTLEDLVARTRAGKAV 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 633 INLLENDALVGVAIAQEGDQVMLATQSGQAIRFELSDVRATGRAsQGVTGIRFKeGRDDRVVSLVILpKGEESEVLAVGS 712
Cdd:PRK05561 631 INLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELPELGKG-KGVKLINLP-KDDDGLVDLRVL-NPEDGLVLLTAG 707
|
730 740
....*....|....*....|...
gi 290469794 713 HGYGKRTPISEYPLQG-RGGMGV 734
Cdd:PRK05561 708 KRKLKLKPSELEKYRGkRARRGR 730
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
26-468 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 668.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 26 VDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLVRLAQPWNLRYPLIDGQGNF 105
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 106 GSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLLVNGSAGIAVGMATSLPPHNLGE 185
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 186 VVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAKL-SRRGIKEAYATGRGSLKVRARVRNEDKNGRAMLVFTEIPYQVNKA 264
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIeGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQVNKA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 265 DLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRLQTSFTVNLLAIV-KGEPKVLTLLEL 343
Cdd:cd00187 241 KLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKLNLKEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 344 MRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSqdaAEARAGLMGRF---SLTEVQAQAILDM 420
Cdd:cd00187 321 LQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQADAILDM 397
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 290469794 421 RLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAI 468
Cdd:cd00187 398 RLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
9-743 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 642.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 9 ITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLVRL 88
Cdd:TIGR01061 6 LEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVRM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 89 AQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLLVNGSA 168
Cdd:TIGR01061 86 SQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 169 GIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAKLS-RRGIKEAYATGRGSLKVRARVRNE-DK 246
Cdd:TIGR01061 166 GIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQgEDGISKAYETGKGKFIIRAKIEIEvNK 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 247 NGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRLQTSFTVN 326
Cdd:TIGR01061 246 NGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQINYNFN 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 327 LLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEARAGLMGR 406
Cdd:TIGR01061 326 MVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKENLIDN 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 407 FSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGDQRRTQITEF--E 484
Cdd:TIGR01061 406 FKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIEDFinQ 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 485 EGFSLEDLIEDEPMVITLTSQGFVKRTPLEAYRAQGRGGMGaqagkTKEEDEAISVFVASMHDTLLIFTNRGRVYGEKVH 564
Cdd:TIGR01061 486 IKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFG-----SKDDDILFAQTIANTTDQILIFTSLGNIINIPVH 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 565 ELPEASRQARGTHIVSLLPLQEGEEVAAL--LNVRDLTQEgYFVFATKNGLIKKTEIKEYQ-NLSSAGLIAINLLENDAL 641
Cdd:TIGR01061 561 KLADIRWKDLGEHLSNKITFDENETIVFVgtMNEFDVDQP-ILVLASKLGMVKRIELTELNiKRNSKATLCIKLKDKDHL 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 642 VGVAIAQEGDQVMLATQSGQAIRFELSDVRATGRASQGVTGIRFKEgrDDRVVSLVILPKgEESEVLaVGSHGYGKRTPI 721
Cdd:TIGR01061 640 ISAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKE--DDQVKSGVIFEA-NESLVL-LTQRGSVKRLSI 715
|
730 740
....*....|....*....|..
gi 290469794 722 SEYPLQGRGGMGVITFNTNEKV 743
Cdd:TIGR01061 716 SELVVTSRAATGKKLLPLKKKP 737
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
28-465 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 639.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 28 RALPDVRDGLKPVQRRILYGAYQDgVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLVRLAQPWNLRYPLIDGQGNFGS 107
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 108 V-DGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLLVNGSAGIAVGMATSLPPHNLGEV 186
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 187 VDALVLMIDNPEVTLeeVMKVLPGPDFPTGA-KLSRRGIKEAYATGRGSLKVRARVRNEDKNGramLVFTEIPYQVNKAD 265
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGgIIGKGGIKEAYKTGRGKITVRAKVEIEDRKT---IVITELPYGVWTSD 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 266 LIAQIASLVRNKVIDEIAALRDESDRqGMRIAVELKRGANPQVVLNKLYKHSRLQTSFTVNLLAIVKGEPKVLTLLELMR 345
Cdd:pfam00521 235 LIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEILK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 346 HYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRGSQDAAEARAGLMGRfsLTEVQAQAILDMRLQRL 425
Cdd:pfam00521 314 EFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE--LSEIQADYLLDMRLRRL 391
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 290469794 426 VGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDEL 465
Cdd:pfam00521 392 TKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
7-458 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 634.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 7 VEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLV 86
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 87 RLAQPWNLRYPLIDGQGNFGSV-DGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLLVN 165
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 166 GSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGaklsrrGIKeayaTGRGSLKVRARVRNED 245
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTG------GEI----VGPGKYVVRGKIEIED 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 246 KNGramLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDES-DRQGMRIAVELKRGANPQVVLNKLYKHSRLQTSFT 324
Cdd:smart00434 231 DNT---IVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTTFS 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 325 VNLLAIV-KGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKAR-ERAHVLEGLLIALDHIDEVIALIRGSQD-AAEARA 401
Cdd:smart00434 308 INMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDlAKEAKE 387
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 290469794 402 GLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLW 458
Cdd:smart00434 388 KLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
2-802 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 627.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 2 SQVLPVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAI 81
Cdd:PRK13979 11 NNIIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 82 YDTLVRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPN 161
Cdd:PRK13979 91 YDAMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 162 LLVNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAKL-SRRGIKEAYATGRGSLKVRAR 240
Cdd:PRK13979 171 LLVNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILiGKKSLLSAYETGEGKVTLRAK 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 241 VRNED-KNGRAMLVFTEIPYQVNKADLIAQIASLVRNK----VIDEIAALRDESDRQGMRIAVELKRGANPQV---VLNK 312
Cdd:PRK13979 251 TKIEKlENGRLGIVITEFPYRRNKAKLLQTISEMTADKkhskALENISDIRDESDRNGIRAVIEFKKSADEDVaekVLKY 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 313 LYKHSRLQTSFTVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRG 392
Cdd:PRK13979 331 LYKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRS 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 393 SQDAAEARAGLMGRFSLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKY 472
Cdd:PRK13979 411 SKSKKDASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVKEKY 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 473 GDQRRTQITEFEE--GFSLEDLIEDEPMVITLTSQGFVKRTPLEAYRaqgRGGMGAQAGKTKEEDEAISVFVASMHDTLL 550
Cdd:PRK13979 491 GDERRTSIIEDDEkaKIDVEELIVVEDVVITLSNEGFIKRIPLKSYN---RSNSNVEDIEYREGDFNKFLIQSNTKDTLL 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 551 IFTNRGRVYGEKVHELPEASRQARGT---HIVSLLPLQEgEEVAALLNVRDLTQEGYFVFATKNGLIKKTEIKEYQNlSS 627
Cdd:PRK13979 568 IFTDKGNMYQIKGINIPEFKWKEKGErldEIIKGIDLES-EKIIEAYSIEDFTPQKDFIFITDSGGIKKTSLDKFVT-NY 645
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 628 AGLIAINLLENDALVGVAIA---QEGDQVMLATQSG-----------------------------QAIRFELSD------ 669
Cdd:PRK13979 646 TKLMALKLKKGEKLIKVKLVdrtREEKFIKIKTKKGlsftveepelepvdrniigyqlfdllpndSIKKVDFCDnyeyke 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 670 -------------VRATGRASQGV------TGIRF-KEGR------------DDRVVSLV-----------------ILP 700
Cdd:PRK13979 726 fyvninkkgiikiSDKDNKSSISVftnsskNLLIFsDEGKvykipafmlqniKNEGINISaltgdfekdekiikiisIFE 805
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 701 KGEESEVLAVGSHGYGKRTPISEYplQGRGGMGVITFNTNEKVGQLAALMRVQGNEDLLVLSRRGNAIRTKVSSIAQYGR 780
Cdd:PRK13979 806 FEEDLSIYFFSKKGLVKKTLLNEF--KGEGNSTQAYKFKHKEDELVNVDIKEHEEKNILLITEKGMAIRFKSEAVNPMGK 883
|
890 900
....*....|....*....|..
gi 290469794 781 ATSGVRVMNLSDKDEIASAFVI 802
Cdd:PRK13979 884 IASGVTGISLKDEDKVIYGSII 905
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
14-701 |
0e+00 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 544.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 14 KQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLVRLAQPWN 93
Cdd:TIGR01062 11 EEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 94 LRYPLIDGQGNFGSVDG-DPPAAQRYTEARLSNIGLELLQDLDKETVPFVPNYDGTQEQPEVLPAALPNLLVNGSAGIAV 172
Cdd:TIGR01062 91 YRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNILLNGTTGIAV 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 173 GMATSLPPHNLGEVVDALVLMIDNPEVTLEEVMKVLPGPDFPTGAKL--SRRGIKEAYATGRGSLKVRARVRNEDkngrA 250
Cdd:TIGR01062 171 GMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAEIidKAEEIRKIYETGRGSFRMRARWKKED----G 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 251 MLVFTEIPYQVNKADLIAQIASLVRNKVIDEIAALRDESDRQG-MRIAVELK-RGANPQVVLNKLYKHSRLQTSFTVNLL 328
Cdd:TIGR01062 247 QIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENpIRVVIVPRsNRVDPDIVMEHLFATTDLEKSYRLNMN 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 329 AI-VKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHVLEGLLIALDHIDEVIALIRgsqDAAEARAGLMGRF 407
Cdd:TIGR01062 327 MIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIR---EEDEPKTILMERF 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 408 SLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAIKDKYGDQRRTQITEFEEG- 486
Cdd:TIGR01062 404 KLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLARRSSLEEREEAk 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 487 -FSLEDLIEDEPMVITLTSQGFVKrtpleayRAQGRgGMGAQAGKTKEEDEAISVFVASMHDTLLIFTNRGRVYGEKVHE 565
Cdd:TIGR01062 484 qVSEIDMIPKEPVTIILSKMGWVR-------SAKGH-DIDLSTLKYKAGDSEKAIIEGKSNQKVVFIDSTGRSYALDPDN 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 566 LPEASRQARGTHIVSLLPLqeGEEVAALLNVRD------LTQEGYFVFATKNGLIKKTEikeyqnlssAGLIAINLLENd 639
Cdd:TIGR01062 556 LPSARGQGEPLTGKLLLPI--GATITNILMYSPnqlllmASDAGYGFLCNFNDLIARNK---------AGKALINLPEN- 623
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 290469794 640 ALVGVAIAQEGDQVMLA--TQSGQAIRFELSDVRATGRAsQGVTGIRFKEG----RDDRVVSLVILPK 701
Cdd:TIGR01062 624 ASVIAPLPVNGDSDMIAaiTEAGRMLVFPIDDLPELSKG-KGNKLIRIPSAnakrGEDGLLDLKIFNK 690
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
14-485 |
5.45e-80 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 269.66 E-value: 5.45e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 14 KQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQ--DGvlpsRKHvKCAKIVGEVMgKFHPHGDAAIYDTLVRLAqp 91
Cdd:PRK09631 9 KDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFEmhDG----KFH-KVANVVGNTM-KYHPHGDASIYEALVNLA-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 92 wNLRYpLIDGQGNFGSV-DGDPPAAQRYTEARLSNIGLELLqdLDKETVPFVPNYDGTQEQPEVLPAALPNLLVNGSAGI 170
Cdd:PRK09631 81 -NKDL-FIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILIQGAEGI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 171 AVGMATSLPPHNLGEVvdalvlmidnpevtLEEVMKVLPG------PDFPTGaklsrrGIKEA--YATGRGSLKVRARVR 242
Cdd:PRK09631 157 AVGMATKILPHNFNEI--------------LQAVKSELLGesfalyPDFPTG------GIVDVseYADGNGKVLVRAKIE 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 243 NEDKNgraMLVFTEIPYQVNKADLIAQIASLVR-NKV-IDEIaalrdeSDRQGMRIAVELK--RGANPQVVLNKLYKHSR 318
Cdd:PRK09631 217 TKDEK---TIVIREIPFGTTTESLIASIEKAARkGKIkISSI------NDYTAENVEIEIKlpRGVYASEVIEALYAYTD 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 319 LQTSFTVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARER--AHVLEGLLIAlDHIDEVIALIRGSQDA 396
Cdd:PRK09631 288 CEVSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKifAKTLEQIFIE-ERIYKRIETISSEEDV 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 397 AEARAGLMGRFS------LTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILGDEKRLWRVVRDELLAikd 470
Cdd:PRK09631 367 ISIVLSELKPFKeelsrdVTEEDIENLLKIPIRRISLFDIDKNQKEIRILNKELKSVEKNLKSIKGYAINFIDKLLA--- 443
|
490
....*....|....*..
gi 290469794 471 KYGD--QRRTQITEFEE 485
Cdd:PRK09631 444 KYSKeyPRKTEISLIKS 460
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
17-565 |
3.63e-67 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 239.52 E-value: 3.63e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 17 FINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQ--DGvlpsrKHVKCAKIVGEVMgKFHPHGDAAIYDTLVRLAQPwNL 94
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMKEmdDG-----RYNKVANVVGHTM-QYHPHGDASIGDALVQLGQK-DL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 95 rypLIDGQGNFGSV-DGDPPAAQRYTEARLSNIGLELLqdLDKETVPFVPNYDGTQEQPEVLPAALPNLLVNGSAGIAVG 173
Cdd:PRK12758 104 ---LIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVG 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 174 MATSLPPHNLGEVVDALVLMIDNPEVTLEevmkvlpgPDFPTGaklsrrGIKE--AYATGR--GSLKVRARVRNEDKNgr 249
Cdd:PRK12758 179 LSTKILPHNFNELIDASIAYLKGKEFKLY--------PDFPTG------GIIDvsNYNDGErgGRVRVRAKIEKLDKK-- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 250 aMLVFTEIPYQVNKADLIAQIASLVRN------KVIDEIAAlrdesdrqGMRIAVELKRGANPQVVLNKLYKHSRLQTSF 323
Cdd:PRK12758 243 -TLVITEIPYGTTTSSLIDSILKANDKgkikikKVEDNTAA--------DVEILVHLAPGVSPDKTIDALYAFTDCEVSI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 324 TVNLLAIVKGEPKVLTLLELMRHYLDHRGLVVRKRTEYELRKARERAHV--LEGLLIAlDHIDEVIALIRGSQDAAEA-R 400
Cdd:PRK12758 314 SPNACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHFasLEKIFIE-ERIYKEIEEAETWEAVIEAiD 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 401 AGL---MGRF--SLTEVQAQAILDMRLQRLVGLERDKLQAEYRELMEEIGRLEAILgdeKRLWRVVRDELLAIKDKYGDQ 475
Cdd:PRK12758 393 KGLepfKKQFirEVTEDDIVRLTEIKIKRISKFDSDKADELIARLEAEIAEVKHHL---AHLTDYAIAYFTNLKKKYGKG 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 476 --RRTQITEFeegfsleDLIEDEPMVItltsqgfvKRTPLEAYRAQGRGGMGAQagktKEEdeaisvFVA--SMHDTLLI 551
Cdd:PRK12758 470 reRKTEIRNF-------DTIEATKVVE--------ANQKLYVNREEGFIGTGLK----KDE------YVAdcSDIDDVIV 524
|
570
....*....|....
gi 290469794 552 FTNRGRVYGEKVHE 565
Cdd:PRK12758 525 FRRDGKYMVTKVAD 538
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
6-118 |
6.55e-58 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 214.97 E-value: 6.55e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 6 PVEITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTL 85
Cdd:NF038098 4 PVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYDTL 83
|
90 100 110
....*....|....*....|....*....|...
gi 290469794 86 VRLAQPWNLRYPLIDGQGNFGSVDGDPPAAQRY 118
Cdd:NF038098 84 VRMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
8-345 |
1.02e-55 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 199.35 E-value: 1.02e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 8 EITDEVKQSFINYAMSVIVDRALPDVRDGLKPVQRRILYGAYQ--DGvlpsrKHVKCAKIVGEVMGkFHPHGDAAIYDTL 85
Cdd:PRK09630 3 DVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFRmdDG-----KMHKVANIAGRTMA-LHPHGDAPIVEAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 86 VRLAqpwNLRYpLIDGQGNFGS-VDGDPPAAQRYTEARLSNIGLELLQDLDkeTVPFVPNYDGTQEQPEVLPAALPNLLV 164
Cdd:PRK09630 77 VVLA---NKGY-LIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVLFNTD--LMTFHDSYDGREKEPDILPAKLPLLLL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 165 NGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTLEevmkvlpgPDFPTGaklsrrGIKEA--YATGRGSLKVRARVR 242
Cdd:PRK09630 151 HGVDGIAVGMTTKIFPHNFCELLEAQIAILNDQPFTLL--------PDFPSG------GTMDAseYQDGLGSITLRASID 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 243 NEDKNgraMLVFTEIPYQVNKADLIAQIASLVRNKVIdEIAALRDESDRQGmRIAVELKRGANPQVVLNKLYKHSRLQTS 322
Cdd:PRK09630 217 IINDK---TLLIKEICPSTTTETLIRSIENAAKRGII-KIDSIQDFSTDLP-HIEIKLPKGIYAKDLLRPLFTHTECQVI 291
|
330 340
....*....|....*....|...
gi 290469794 323 FTVNLLAIVKGEPKVLTLLELMR 345
Cdd:PRK09630 292 LTSRPTAIYQNKPVETSISEILR 314
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
15-443 |
2.25e-47 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 174.47 E-value: 2.25e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 15 QSFIN-----YAMSVIVDRALPDVRDGLKPVQRRILYGAYQDGVLPSRKHVKCAKIVGEVMGKFHPHGDAAIYDTLVRLA 89
Cdd:PHA02592 9 KSIVNnealeYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVADLGYHHGETSAQDAGALMA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 90 QPWNLRYPLIDGQGNFGSVDGDPPAAQRYTEARLSniglELLQDLDKETvpfvpNYDGTQEQPEVLPAA-----LPNLLV 164
Cdd:PHA02592 89 NTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARVH----DNFRKIYKDE-----DLAPVHEDPEHIPPAfylpiIPMVLL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 165 NGSAGIAVGMATSLPPHNLGEVVDALVLMIDNPEVTleevmkvLPGPDFPtgaklsrrGIK-EAYATGRGSLKVRARVRn 243
Cdd:PHA02592 160 NGVSGIATGYATNILPHSPKSVIKAVLAALNGKDIT-------EPKVQFP--------EFKgEVVEIEPGSYEIRGTYE- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 244 edKNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVIDEIaalrDESDRQGMRIAVELKRGANPQVVLNKLYKHSRLQTSF 323
Cdd:PHA02592 224 --LNGKTKLHITEIPVKYDRETYVAVLDPLEEKGKIVSY----DDCTEDGFRFKVTLKREENEEATHEKIMKDFGLIERV 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 324 TVNLLAIV-KGEPKVL-TLLELMRHYLDHRGLVVRKRTEYELRKARERahvLEGLLIALDHIDEVIALIRGSQDaaEARA 401
Cdd:PHA02592 298 SQNITVINeNGKLKVYeNAEDLIRDFVEIRKTYVQKRIQYEIKETEEA---FDLALAKAEFIKRVIAGEIVLQG--KTRS 372
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 290469794 402 GLMgrfslTEVQAQAILDMRLQRLVGL--------ERDKLQAEYRELMEE 443
Cdd:PHA02592 373 ELT-----EELSDNKDFGEYADKLVAMniysmtsdEREKLQKEAEELEKE 417
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
7-565 |
1.13e-23 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 107.82 E-value: 1.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 7 VEITDEVKQSFINYAmsvIVD--RALPDVRDGLKPVQRRILYGAYqdgvlpsRKH----VKCAKIVGEVMGK--FHpHGD 78
Cdd:PTZ00108 660 LTYSDFVNKELILFS---IADneRSIPSLVDGLKPGQRKILFACF-------KRNlkneIKVAQLSGYVSEHsaYH-HGE 728
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 79 AAIYDTLVRLAQPW------NLRYPliDGQgnFGS--VDGDPPAAQRYTEARLSNIGLELLQDLDKetvpFVPNY---DG 147
Cdd:PTZ00108 729 QSLQQTIVGMAQNFvgsnniNLLYP--CGQ--FGSrlQGGKDHAAARYIFTKLSKITRYIFPEEDD----PILDYledDG 800
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 148 TQEQPEVLPAALPNLLVNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNpevtlEEVMKVLPgpdFPTGAKlsrrGIKEA 227
Cdd:PTZ00108 801 QSVEPFYYVPIIPMVLVNGAEGIGTGFSTSIPNYNPLDIIDNLRRRLNG-----EEVRPLVP---WYRGFK----GTIER 868
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 228 YATGRGSLKVRARVRNEDKngramLVFTEIPYQVNKADLIAQIASLVrNKVIDEIAALRDESDRQGMRIAVELKRGANPQ 307
Cdd:PTZ00108 869 NPKGKFISKGIYEKVPDGT-----VEITELPIGKWTEDYKEFLESET-LKEKDVIVDYRDYSTANTVHFTVKLNDGVLEQ 942
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 308 VVLNKLYKHSRLQTSFTVNLLAIVKGE---PKVLTLLELMRHYLDHRGLVVRKRTEY---ELRKARER--------AHVL 373
Cdd:PTZ00108 943 WEEEGIEKVFKLKSTISTTNMVLFDENgkiKKYSDALDILKEFYLVRLDLYKKRKEYllgKLERELARlsnkvrfiKHVI 1022
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 374 EGLLI----------------ALDHIDEVIAL------IRGSQDAAEARAGLMGRFSLTEVQAQA---ILDMRLQRLVgL 428
Cdd:PTZ00108 1023 NGELVitnakkkdlvkelkklGYVRFKDIIKKksekitAEEEEGAEEDDEADDEDDEEELGAAVSydyLLSMPIWSLT-K 1101
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 429 ER-DKLQAEYRELMEEIGRLEAIlgDEKRLWrvvRDELLAIKDKYGDQRRTQITEFEEGFSLEdliedepmVITLTSQGF 507
Cdd:PTZ00108 1102 EKvEKLNAELEKKEKELEKLKNT--TPKDMW---LEDLDKFEEALEEQEEVEEKEIAKEQRLK--------SKTKGKASK 1168
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 290469794 508 VKRTPLEAYRAQGRggmgaqaGKTKEEDEAISVFVASMHDTLLIFTNRGRVYGEKVHE 565
Cdd:PTZ00108 1169 LRKPKLKKKEKKKK-------KSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSN 1219
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
16-377 |
5.26e-21 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 99.01 E-value: 5.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 16 SFINYAM----SVIVDRALPDVRDGLKPVQRRILYGAYQDGVlpsRKHVKCAKIVGEVM--GKFHpHGDAAIYDTLVRLA 89
Cdd:PLN03128 657 DFINKELilfsQADLARSIPSMVDGLKPSQRKVLFACFKRNL---KSEIKVAQLSGYVAehSAYH-HGEASLASTIIGMA 732
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 90 QPW------NLRYPlidgQGNFGS--VDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVpNYDGTQEQPEVLPAALPN 161
Cdd:PLN03128 733 QDFvgsnniNLLTP----SGQFGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYL-NEDGQSIEPEWYCPIIPM 807
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 162 LLVNGSAGIAVGMATSLPPHNLGEVVDALVLMIDNpevtlEEVMKVLPgpdFPTGAKlsrRGIKEAYATGRGSLKVRARV 241
Cdd:PLN03128 808 VLVNGSEGIGTGWSTFIPNYNPRDIIANIRRLLRG-----EELEPMHP---WYRGFK---GTITEVSTSRSGSYTVTGII 876
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 242 rneDKNGRAMLVFTEIPYQVNKADLIAQIASLVRNKVID--EIAALRDESDRQGMRIAVELKRGANPQVVLNKLYKHSRL 319
Cdd:PLN03128 877 ---EQIGDTTIRITELPVRKWTQDYKEFLEALLTGTKKKepEIKDFKENHTDTTVHFTVTLSEEKMARALAEGLEKKFKL 953
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 290469794 320 QTSF-TVNLLA------IVKGEPKVLTLLELMRHYLDH---RGLVVRKRTEYELRKARERAHVLEGLL 377
Cdd:PLN03128 954 STTIsTSNMHLfdkdgkIKKYDSPEDILEEFFHLRLDLyvkRKEVLLENLEYELKKLDNKARFILAVV 1021
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
7-188 |
3.76e-16 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 83.37 E-value: 3.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 7 VEITDEVKQSFINYAMSVIvDRALPDVRDGLKPVQRRILYGAYQDGVlpsRKHVKCAKIVGEV--MGKFHpHGDAAIYDT 84
Cdd:PLN03237 678 VKYSDFVNKELILFSMADL-QRSIPSMVDGLKPGQRKILFCSFKRNF---VKEAKVAQLSGYVseHSAYH-HGEQSLAST 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 290469794 85 LVRLAQPW------NLRYPlidgQGNFG--SVDGDPPAAQRYTEARLSNIGLELLQDLDKETVPFVpNYDGTQEQPEVLP 156
Cdd:PLN03237 753 IIGMAQDFvgsnniNLLLP----NGQFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYM 827
|
170 180 190
....*....|....*....|....*....|..
gi 290469794 157 AALPNLLVNGSAGIAVGMATSLPPHNLGEVVD 188
Cdd:PLN03237 828 PIIPTVLVNGAEGIGTGWSTFIPNYNPRDIVA 859
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
651-700 |
2.94e-11 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 59.04 E-value: 2.94e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 290469794 651 DQVMLATQSGQAIRFELSDVRATGRASQGVTGIRFKEgrDDRVVSLVILP 700
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKE--GDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
756-802 |
7.15e-11 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 57.88 E-value: 7.15e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 290469794 756 EDLLVLSRRGNAIRTKVSSIAQYGRATSGVRVMNLSDKDEIASAFVI 802
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
498-544 |
6.03e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 55.19 E-value: 6.03e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 290469794 498 MVITLTSQGFVKRTPLEAYRAQGRGGMGAQAGKTKEEDEAISVFVAS 544
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
706-752 |
1.02e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.72 E-value: 1.02e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 290469794 706 EVLAVGSHGYGKRTPISEYPLQGRGGMGVITFNTNEKvGQLAALMRV 752
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEG-DKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
547-597 |
4.11e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 44.40 E-value: 4.11e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 290469794 547 DTLLIFTNRGRVYGEKVHELPEASRQARGTHIVSllpLQEGEEVAALLNVR 597
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN---LKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
604-646 |
5.52e-06 |
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DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 44.02 E-value: 5.52e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 290469794 604 YFVFATKNGLIKKTEIKEYQNLS--SAGLIAINLLENDALVGVAI 646
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGrgAKGVKGINLKEGDKVVSVLV 46
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