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Conserved domains on  [gi|283819543|gb|ADB41381|]
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transcriptional regulator, AraC family [Spirosoma linguale DSM 74]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 11454538)

AraC family transcriptional regulator controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_18 pfam12833
Helix-turn-helix domain;
211-290 3.06e-22

Helix-turn-helix domain;


:

Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 88.03  E-value: 3.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  211 YASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLL-FHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYRA 289
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 283819543  290 S 290
Cdd:pfam12833  81 R 81
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
126-292 5.27e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


:

Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.54  E-value: 5.27e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 126 HELLLTEADVMFVEDMLAKINAEYQQPNEWQQRMLTAYLTVLLTYLSRLYTEQFESKPASTDNLLLKKYQAKINEHFRER 205
Cdd:COG2207   89 LLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 206 HQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPA 285
Cdd:COG2207  169 LTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPS 248


                 ....*..
gi 283819543 286 EYRASIR 292
Cdd:COG2207  249 EYRKRLR 255
 
Name Accession Description Interval E-value
HTH_18 pfam12833
Helix-turn-helix domain;
211-290 3.06e-22

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 88.03  E-value: 3.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  211 YASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLL-FHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYRA 289
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 283819543  290 S 290
Cdd:pfam12833  81 R 81
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
126-292 5.27e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.54  E-value: 5.27e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 126 HELLLTEADVMFVEDMLAKINAEYQQPNEWQQRMLTAYLTVLLTYLSRLYTEQFESKPASTDNLLLKKYQAKINEHFRER 205
Cdd:COG2207   89 LLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 206 HQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPA 285
Cdd:COG2207  169 LTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPS 248


                 ....*..
gi 283819543 286 EYRASIR 292
Cdd:COG2207  249 EYRKRLR 255
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
208-288 1.18e-19

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 81.45  E-value: 1.18e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543   208 VSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEY 287
Cdd:smart00342   4 LEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPSEY 83


                   .
gi 283819543   288 R 288
Cdd:smart00342  84 R 84
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 195-292 1.72e-12

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 66.72  E-value: 1.72e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 195 QAKINEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNR 274
Cdd:COG4977  216 QAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRR 295

                         90
                 ....*....|....*...
gi 283819543 275 FFKRETELTPAEYRASIR 292
Cdd:COG4977  296 AFRRRFGVSPSAYRRRFR 313
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
198-294 2.30e-08

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 54.21  E-value: 2.30e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 198 INEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFK 277
Cdd:PRK10572 192 ISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFK 271

                         90
                 ....*....|....*..
gi 283819543 278 RETELTPAEYRASIREM 294
Cdd:PRK10572 272 KCTGASPSEFRARCEEK 288
adjacent_YSIRK TIGR04094
YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only ...
 174-288 1.07e-07

YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.


Pssm-ID: 274977 [Multi-domain]  Cd Length: 383  Bit Score: 52.37  E-value: 1.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  174 LYTEQFESKPASTDNLLLKKYQAKINEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLfHT 253
Cdd:TIGR04094 270 YFTELLHEISINHHSPLIRAVIQYINLNLYDPLKVEEIAKQFFMSESKLRKLFKKEMGISIQEYISKRKIEEAKYLL-RS 348

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 283819543  254 PQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYR 288
Cdd:TIGR04094 349 QIPVSEVSNELGFYDLSHFSRTFKKHTGVSPKQYQ 383
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
42-288 5.54e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 49.90  E-value: 5.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  42 LVPHRKDHYLLVFIRQAGSRQWIDMTPYVLKDNTFYFTGPDQIIVKEGFNQLWSTGIAFTKEflSFQENAALSK-LPLIQ 120
Cdd:PRK13501  31 FVEHTHQFCEIVIVWRGNGLHVLNDHPYRITCGDVFYIQAADHHSYESVHDLVLDNIIYCPE--RLHLNAQWHKlLPPLG 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 121 NPHNGHELLLTEADVMFVEDMLAKINAEYQQPNEWQqRMLTAYLTVLLTYLSRLYTEQFESKPASTD----NLLLKKYQA 196
Cdd:PRK13501 109 PEQNQGYWRLTTQGMAQARPIIQQLAQESRKTDSWS-IQLTEVLLLQLAIVLKRHRYRAEQAHLLPDgeqlDLIMSALQQ 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 197 KINE-----HFRERHQVSDYAsllnvsagyLSEVVKAQSGKpAITHIHERLVLEARRLLFHTPQSL-KEIAFDLGFSDAS 270
Cdd:PRK13501 188 SLGAyfdmaDFCHKNQLVERS---------LKQLFRQQTGM-SISHYLRQIRLCHAKCLLRGSEHRiSDIAARCGFEDSN 257

                        250
                 ....*....|....*...
gi 283819543 271 YFNRFFKRETELTPAEYR 288
Cdd:PRK13501 258 YFSAVFTREAGMTPRDYR 275
 
Name Accession Description Interval E-value
HTH_18 pfam12833
Helix-turn-helix domain;
211-290 3.06e-22

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 88.03  E-value: 3.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  211 YASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLL-FHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYRA 289
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 283819543  290 S 290
Cdd:pfam12833  81 R 81
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
126-292 5.27e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.54  E-value: 5.27e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 126 HELLLTEADVMFVEDMLAKINAEYQQPNEWQQRMLTAYLTVLLTYLSRLYTEQFESKPASTDNLLLKKYQAKINEHFRER 205
Cdd:COG2207   89 LLLVGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 206 HQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPA 285
Cdd:COG2207  169 LTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPS 248


                 ....*..
gi 283819543 286 EYRASIR 292
Cdd:COG2207  249 EYRKRLR 255
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
208-288 1.18e-19

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 81.45  E-value: 1.18e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543   208 VSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEY 287
Cdd:smart00342   4 LEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPSEY 83


                   .
gi 283819543   288 R 288
Cdd:smart00342  84 R 84
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 195-292 1.72e-12

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 66.72  E-value: 1.72e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 195 QAKINEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNR 274
Cdd:COG4977  216 QAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRR 295

                         90
                 ....*....|....*...
gi 283819543 275 FFKRETELTPAEYRASIR 292
Cdd:COG4977  296 AFRRRFGVSPSAYRRRFR 313
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 198-289 8.21e-11

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 61.99  E-value: 8.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 198 INEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLfHTPQSLKEIAFDLGFSDASYFNRFFK 277
Cdd:COG2169   93 IEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQLL-QTGLSVTDAAYAAGFGSLSRFYEAFK 171

                         90
                 ....*....|..
gi 283819543 278 RETELTPAEYRA 289
Cdd:COG2169  172 KLLGMTPSAYRR 183
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
198-294 2.30e-08

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 54.21  E-value: 2.30e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 198 INEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFK 277
Cdd:PRK10572 192 ISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFK 271

                         90
                 ....*....|....*..
gi 283819543 278 RETELTPAEYRASIREM 294
Cdd:PRK10572 272 KCTGASPSEFRARCEEK 288
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 251-292 7.60e-08

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 52.73  E-value: 7.60e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 283819543 251 FHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYRASIR 292
Cdd:PRK09685 261 AADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRRKFR 302
adjacent_YSIRK TIGR04094
YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only ...
 174-288 1.07e-07

YSIRK-targeted surface antigen transcriptional regulator; Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.


Pssm-ID: 274977 [Multi-domain]  Cd Length: 383  Bit Score: 52.37  E-value: 1.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  174 LYTEQFESKPASTDNLLLKKYQAKINEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLfHT 253
Cdd:TIGR04094 270 YFTELLHEISINHHSPLIRAVIQYINLNLYDPLKVEEIAKQFFMSESKLRKLFKKEMGISIQEYISKRKIEEAKYLL-RS 348

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 283819543  254 PQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYR 288
Cdd:TIGR04094 349 QIPVSEVSNELGFYDLSHFSRTFKKHTGVSPKQYQ 383
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
241-288 2.30e-07

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 51.22  E-value: 2.30e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 283819543 241 RLvLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYR 288
Cdd:PRK13503 224 RL-LKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSPRDIR 270
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
183-288 3.10e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 50.82  E-value: 3.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 183 PASTDNLLLKKYQAKINEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAF 262
Cdd:PRK13502 170 PATSRETLLDKLITALANSLECPFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISM 249

                         90       100
                 ....*....|....*....|....*.
gi 283819543 263 DLGFSDASYFNRFFKRETELTPAEYR 288
Cdd:PRK13502 250 QCGFEDSNYFSVVFTRETGMTPSQWR 275
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
42-288 5.54e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 49.90  E-value: 5.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  42 LVPHRKDHYLLVFIRQAGSRQWIDMTPYVLKDNTFYFTGPDQIIVKEGFNQLWSTGIAFTKEflSFQENAALSK-LPLIQ 120
Cdd:PRK13501  31 FVEHTHQFCEIVIVWRGNGLHVLNDHPYRITCGDVFYIQAADHHSYESVHDLVLDNIIYCPE--RLHLNAQWHKlLPPLG 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 121 NPHNGHELLLTEADVMFVEDMLAKINAEYQQPNEWQqRMLTAYLTVLLTYLSRLYTEQFESKPASTD----NLLLKKYQA 196
Cdd:PRK13501 109 PEQNQGYWRLTTQGMAQARPIIQQLAQESRKTDSWS-IQLTEVLLLQLAIVLKRHRYRAEQAHLLPDgeqlDLIMSALQQ 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 197 KINE-----HFRERHQVSDYAsllnvsagyLSEVVKAQSGKpAITHIHERLVLEARRLLFHTPQSL-KEIAFDLGFSDAS 270
Cdd:PRK13501 188 SLGAyfdmaDFCHKNQLVERS---------LKQLFRQQTGM-SISHYLRQIRLCHAKCLLRGSEHRiSDIAARCGFEDSN 257

                        250
                 ....*....|....*...
gi 283819543 271 YFNRFFKRETELTPAEYR 288
Cdd:PRK13501 258 YFSAVFTREAGMTPRDYR 275
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
40-288 6.49e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 50.10  E-value: 6.49e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  40 DLLVPHRKDHYLLVFIRQAGSRQWIDMTPYVLKDNTFYFTGPDQIIVKEGFNQLWSTGIAFTKEFLSFQENAAlSKLPLI 119
Cdd:PRK13500  59 DVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQ-GAIPGF 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 120 QNPHNGHELLLTEADVMFVEDMLAKINAEYQQPNEWQQRMLTAYLTVLLTYLSR-LYTEqfESKPASTDNLLLKKYQAKI 198
Cdd:PRK13500 138 SASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRhRYTS--DSLPPTSSETLLDKLITRL 215

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 199 NEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKR 278
Cdd:PRK13500 216 AASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTR 295

                        250
                 ....*....|
gi 283819543 279 ETELTPAEYR 288
Cdd:PRK13500 296 ETGMTPSQWR 305
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 251-288 7.37e-06

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 42.14  E-value: 7.37e-06
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 283819543  251 FHTPQSLKEIAFDLGFSdASYFNRFFKRETELTPAEYR 288
Cdd:pfam00165   5 LSTNLTIADIADELGFS-RSYFSRLFKKYTGVTPSQYR 41
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 239-292 8.94e-06

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 46.59  E-value: 8.94e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 283819543 239 HERLVLEARRLL---FHTPQSLKEIAFDLGFSdASYFNRFFKRETELTPAEYRASIR 292
Cdd:COG2169   82 RADLVARACRLIeagAEDRPSLEDLAARLGLS-PRHLRRLFKAHTGVTPKAYARARR 137
ftrA PRK09393
transcriptional activator FtrA; Provisional
 198-292 5.77e-05

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 43.80  E-value: 5.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 198 INEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGK-PAITHIHERLvLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFF 276
Cdd:PRK09393 227 MRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMtPAEWLLRERL-ARARDLLESSALSIDQIAERAGFGSEESLRHHF 305

                         90
                 ....*....|....*.
gi 283819543 277 KRETELTPAEYRASIR 292
Cdd:PRK09393 306 RRRAATSPAAYRKRFG 321
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
198-291 9.79e-05

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 41.06  E-value: 9.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 198 INEHFRERHQVSDYASLLNVSAGYLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFK 277
Cdd:PRK10219  14 IDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFR 93

                         90
                 ....*....|....
gi 283819543 278 RETELTPAEYRASI 291
Cdd:PRK10219  94 RQFDRTPSDYRHRL 107
PRK10296 PRK10296
DNA-binding transcriptional regulator ChbR; Provisional
 221-288 4.41e-04

DNA-binding transcriptional regulator ChbR; Provisional


Pssm-ID: 182362 [Multi-domain]  Cd Length: 278  Bit Score: 40.90  E-value: 4.41e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 283819543 221 YLSEVVKAQSGKPAITHIHERLVLEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYR 288
Cdd:PRK10296 204 YLTRATRRYYGKTPMQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPGSYR 271
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 66-289 2.64e-03

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 38.89  E-value: 2.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543  66 MTPYVLKDNTFYFTgPDQIIVKEGFN--QLWSTGIAFTKEFLSFqENAALSKlPLIQnPHNGHELLLTEADVMFVEDMLA 143
Cdd:PRK15186  65 MLIFLAKDQTIHIT-MEETHEQLNYNliELDSASIKNAYNFFLY-EHADFSA-PLTK-PTTKHLLAPIETGVARVFNLLH 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283819543 144 KINAEYQQPNEWQQrmltayltvlltYLSRLYTEQFESKPAS-------TDNLLLKKYQAKINEHFRERHQVSDYASLLN 216
Cdd:PRK15186 141 SSNKSQKLSQDKKE------------YLIRFLLSEFIYEPEAfalfrelSQNTLAENIYNIIISDISRKWALKDISDSLY 208

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 283819543 217 VSAGYLSEVVKAQSGKPAITHIHERLVlEARRLLFHTPQSLKEIAFDLGFSDASYFNRFFKRETELTPAEYRA 289
Cdd:PRK15186 209 MSCSTLKRKLKQENTSFSEVYLNARMN-KATKLLRNSEYNITRVAYMCGYDSASYFTCVFKKHFKTTPSEFLA 280
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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