|
Name |
Accession |
Description |
Interval |
E-value |
| COG3292 |
COG3292 |
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; |
25-1035 |
4.39e-72 |
|
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];
Pssm-ID: 442521 [Multi-domain] Cd Length: 924 Bit Score: 259.92 E-value: 4.39e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 25 AKSIRQFNVQSWTRQTGLPADKIGDVVQTPDGFIWLGTQNGLVRFDGLEFKVVpitlpyaggqdvaklsiapdgalwfai 104
Cdd:COG3292 16 AQAAQQYRFRHLTVEDGLPQNSVNSIAQDSDGFLWIGTEDGLNRYDGYEFKVF--------------------------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 105 nrggfgrfdgqKFSPIDDARFQDPRIAAgtILVGRDGAIWTGTVNGLNRWvkDRPAESF---YAESVQPSGTVLALHEDA 181
Cdd:COG3292 69 -----------RHDPGDPNSLPSNYIRA--LLEDSDGRLWIGTDGGLSRY--DPKTDKFtryPLDPGLPNNSIRSIAEDS 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 182 AGRMWVGTGGsGLYYHD--GKSLHELRDESLRGYSTVALTSDARGAIWlatarslrrlapgaertevlltempvsavlVD 259
Cdd:COG3292 134 DGNIWVGTSN-GLYRYDpkTGKFKRFTLDGLPSNTITSLAEDADGNLW------------------------------VD 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 260 RQGVVWFGTTSRGLGRY--ADGEFTFLGK---AEGLASDNVFSLFEDREGSLWVGT-PEGLSQL--TDLKFPIF--SKPE 329
Cdd:COG3292 183 SDGNLWIGTDGNGLYRLdpNTGKFEHITHdpdPNSLSSNSIYSLFEDREGNLWVGTyGGGLNYLdpNNSKFKSYrhNDPN 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 330 GLLEGSAIAVTPARAGGVWAAM-----ASGVSYFDGRRAHNIT-DRELLPNPYQRTIFEARNGDLYVGDGDRNIHvfrdd 403
Cdd:COG3292 263 GLSGNSVRSIAEDSDGNLWIRLwigtyGGGLFRLDPKTGKFKRyNPNGLPSNSVYSILEDSDGNLWIGTSGGGLY----- 337
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 404 rllyrvhtelwpdamtedhesvlvgvgwmLYRLREGGLQPFEFQPGQDPNlgWINRLYVNADGTIWAGTNSGVARI--RD 481
Cdd:COG3292 338 -----------------------------RYDPKTGKFTKFSEDNGLSNN--FIRSILEDSDGNLWVGTNGGLYRLdpKT 386
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 482 GLVTRW---SPAQGLSSDRVHFVFVDVDGAVWAGlpT---GLARI--KDERVANVRLADGLPDQRIFAIVPDEVGNFWIS 553
Cdd:COG3292 387 GKFTNFthdPDKNGLSSNYINSIFEDSDGRLWIG--TdggGLYRYdpKTGKFKHFTTKDGLPSNTIYSILEDDNGNLWNF 464
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 554 SGrgvfraareklnaiadgqpvelgaelfggleAVKFTDRTDQGFSGCRSNDGRIWFPNPLGVMTIDPTKYFRNPIAPPV 633
Cdd:COG3292 465 NS-------------------------------ASNLGLLSLLGGLLGGLNLGNAIKLPLSNLGLLLTLLLLGINLSLVR 513
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 634 HLEQVRVNGEERPVTEKLVLQPGENRVEFTFTALSYIAPRKLRARYRLHGLEEEWVDAGPRRSALYSRLAPGNYTFQVQA 713
Cdd:COG3292 514 SLISLLTLLLLALLLLLSLLLLLLLLLLLLLLLLLLLLLLLLLILLLLLLRLLLLLLLLELLERLLALLLEIELLLTLLL 593
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 714 CNADGVWNTTGAELSFRLLPPFHETGWFYALCGLVSLAAVVGGHRWRVRHMEVARLKLQAERDLLETKVTERTAELAHEH 793
Cdd:COG3292 594 LLLLLLLLLLLLLILLLLLLLLLLLLILLLLLLLLLLLLILLLLLLLLLLLLLLLLRLLLELLLLELELLLELLLLLAEL 673
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 794 ALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSGALIGRSDAELMPDSDVRAALAGEQEIIRTGQPLIGQVEVE 873
Cdd:COG3292 674 ILELLLILLLLLLLLLLALLLLLLLLLALKLLLLLLLILLLLLLLLGLLLLLLDLVLLLLLLILLIILLLLILLEELLLA 753
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 874 SEQAGNKRWLLTSKMPLRNKAGEIIGTFGISKDITMLKEAEAKLIEAHRQLLVTSRQAGMAEVATSVLHNVGNVLNSVNV 953
Cdd:COG3292 754 NDIELEGILLLILLVLELLLELALGLILLLKLLLLLLNLLIGLIKETVSEGSILLKLLVLELELAESVLIALEGLGKIDL 833
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 954 SASLVSEKMRNARLDHLEKAVAMLQAHAGDLAEFLVSDPKGRKLPEFFALLSSQLTAERDEIARELEHLRKNVDHIKEVV 1033
Cdd:COG3292 834 LDILELILLELELGLLLGLLLLLLLEILLLSLVELLLELLEGIILALDLLLGSLSLVILLGLNELLLAELEEIDALLIEL 913
|
..
gi 177841171 1034 AM 1035
Cdd:COG3292 914 LL 915
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
784-1198 |
8.52e-40 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 153.58 E-value: 8.52e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 784 ERTAELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSDVRAALagEQEIIRTG 863
Cdd:COG5000 80 EQREELEERRRYLETILENLPAGVIVLDADGRITLANPAAERLLGIPLE-ELIGKPLEELLPELDLAELL--REALERGW 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 864 QpliGQVEVeseQAGNKRWLLTSKMPLRNkageiIGTFGISKDITMLKEAEaklieahrqllvtsRQAGMAEVATSVLHN 943
Cdd:COG5000 157 Q---EEIEL---TRDGRRTLLVRASPLRD-----DGYVIVFDDITELLRAE--------------RLAAWGELARRIAHE 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 944 VGNVLNSVNVSASLVSEKmrnarldhlekavamlqahagdlaeflvsdpkgrklpeffalLSSQLTAERDEIARELEHLR 1023
Cdd:COG5000 212 IKNPLTPIQLSAERLRRK------------------------------------------LADKLEEDREDLERALDTII 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1024 KNVDHIKEVVAMQQSYAKV-AGVAESMPLTDVVDDALRMYELELARHQITLDRDYQAQ-PVLRTDRHKLMQILVNLIQNA 1101
Cdd:COG5000 250 RQVDRLKRIVDEFLDFARLpEPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDlPEVLADRDQLEQVLINLLKNA 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1102 KYACKEsnrpDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLhsgALVAK---ELGGSLTAE 1178
Cdd:COG5000 330 IEAIEE----GGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGL---AIVKKiveEHGGTIELE 402
|
410 420
....*....|....*....|
gi 177841171 1179 SgGAGEGATFTVELPLQASA 1198
Cdd:COG5000 403 S-RPGGGTTFTIRLPLAEEA 421
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
788-1201 |
1.81e-39 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 150.77 E-value: 1.81e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 788 ELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSDVRAALAgeQEIIRTGQPLI 867
Cdd:COG3852 1 ALRESEELLRAILDSLPDAVIVLDADGRITYVNPAAERLLGLSAE-ELLGRPLAELFPEDSPLRELL--ERALAEGQPVT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 868 -GQVEVESEQaGNKRWLLTSKMPLRNKAGEIiGTFGISKDITMLKEAEaklieahRQLLVTSRQAGMAEVATSVLHNVGN 946
Cdd:COG3852 78 eREVTLRRKD-GEERPVDVSVSPLRDAEGEG-GVLLVLRDITERKRLE-------RELRRAEKLAAVGELAAGLAHEIRN 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 947 VLNSVnvsaslvsekmRNArldhlekavamlqahagdlAEFLVSDPKGRKLPEFFALLSSQltAER-DEIARELEHLRKN 1025
Cdd:COG3852 149 PLTGI-----------RGA-------------------AQLLERELPDDELREYTQLIIEE--ADRlNNLVDRLLSFSRP 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1026 VDHIKEVVAmqqsyakvagvaesmpLTDVVDDALRMYELELARHqITLDRDYQAQ-PVLRTDRHKLMQILVNLIQNAKYA 1104
Cdd:COG3852 197 RPPEREPVN----------------LHEVLERVLELLRAEAPKN-IRIVRDYDPSlPEVLGDPDQLIQVLLNLVRNAAEA 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1105 CKESN------RPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLhsgALVAK---ELGGSL 1175
Cdd:COG3852 260 MPEGGtitirtRVERQVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKEKGTGLGL---AIVQKiveQHGGTI 336
|
410 420
....*....|....*....|....*.
gi 177841171 1176 TAESgGAGEGATFTVELPLQASAGQE 1201
Cdd:COG3852 337 EVES-EPGKGTTFRIYLPLEQAEEEP 361
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
824-1195 |
2.24e-39 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 150.72 E-value: 2.24e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 824 AEALGLSSSGALIGRSDAELMPDSDVRAALAGEQEIIRTGQPLIGQVEVESEQAGNKRWLLTSKMPLRNKAGEIIGTFGI 903
Cdd:COG4191 33 LALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEEL 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 904 SKDITMLKEAEAKLIEAHRQLLVTSRQAGMAEVATSVLHNVGNVLNSVNVSASLVSEKMRNarldhlekavamlQAHAGD 983
Cdd:COG4191 113 ERDITELERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGNAELLRRRLED-------------EPDPEE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 984 LAEFLvsdpkgrklpeffallssqltaerDEIARELEHLRKNVDHIKEVVAMQQSyakvagVAESMPLTDVVDDALRMYE 1063
Cdd:COG4191 180 LREAL------------------------ERILEGAERAAEIVRSLRAFSRRDEE------EREPVDLNELIDEALELLR 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1064 LELARHQITLDRDYQAQ-PVLRTDRHKLMQILVNLIQNAKYACKEsnRPDRKIILRVTQADGRARVAVVDNGIGIPRESL 1142
Cdd:COG4191 230 PRLKARGIEVELDLPPDlPPVLGDPGQLEQVLLNLLINAIDAMEE--GEGGRITISTRREGDYVVISVRDNGPGIPPEVL 307
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 177841171 1143 SRIFAHGYTTRKDGHGFGL-----HSgalVAKELGGSLTAESgGAGEGATFTVELPLQ 1195
Cdd:COG4191 308 ERIFEPFFTTKPVGKGTGLglsisYG---IVEKHGGRIEVES-EPGGGTTFTITLPLA 361
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
769-1195 |
1.89e-33 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 136.01 E-value: 1.89e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 769 LKLQAERDLLETKVTErtAELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSD 848
Cdd:COG5805 134 AAILALRDITKKKKIE--EILQEQEERLQTLIENSPDLICVIDTDGRILFINESIERLFGAPRE-ELIGKNLLELLHPCD 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 849 VRAALAGEQEIIRTGQPLIGQVEVESEQaGNKRWLLTSKMPLRNKAGEIIGTFGISKDITMLKEAEaklieahrQLLVTS 928
Cdd:COG5805 211 KEEFKERIESITEVWQEFIIEREIITKD-GRIRYFEAVIVPLIDTDGSVKGILVILRDITEKKEAE--------ELMARS 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 929 RQAGMA-EVATSVLHNVGNVLNSVNVSASLVSEKMRNAR------LDHLEKAVAMLQahagdlaEFLVsdpkgrklpeff 1001
Cdd:COG5805 282 EKLSIAgQLAAGIAHEIRNPLTSIKGFLQLLQPGIEDKEeyfdimLSELDRIESIIS-------EFLA------------ 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1002 allssqltaerdeIARELEHLRKNVD---HIKEVVAMQQSYAKVAGVAESMPLTDVVddalrmyelelarhqitldrdyq 1078
Cdd:COG5805 343 -------------LAKPQAVNKEKENineLIQDVVTLLETEAILHNIQIRLELLDED----------------------- 386
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1079 aqPVLRTDRHKLMQILVNLIQNAKYACkesnrPDRKII-LRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGH 1157
Cdd:COG5805 387 --PFIYCDENQIKQVFINLIKNAIEAM-----PNGGTItIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKEKGT 459
|
410 420 430
....*....|....*....|....*....|....*...
gi 177841171 1158 GFGLHSGALVAKELGGSLTAESgGAGEGATFTVELPLQ 1195
Cdd:COG5805 460 GLGLMVSYKIIENHNGTIDIDS-KVGKGTTFTITLPLS 496
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
1003-1195 |
3.11e-32 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 128.87 E-value: 3.11e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1003 LLSSQLTAERDE----IARELEHLRKNVDHIKEVVAMQQSyaKVAGVAESMPLTDVVDDALRMYELELARHQITLDRDYQ 1078
Cdd:COG0642 134 LLLEELDEEQREyletILRSADRLLRLINDLLDLSRLEAG--KLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLP 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1079 AQPV-LRTDRHKLMQILVNLIQNA-KYAckesnRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTT---- 1152
Cdd:COG0642 212 DDLPtVRGDPDRLRQVLLNLLSNAiKYT-----PEGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTdpsr 286
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 177841171 1153 RKDGHGFGLhsgALV---AKELGGSLTAESgGAGEGATFTVELPLQ 1195
Cdd:COG0642 287 RGGGTGLGL---AIVkriVELHGGTIEVES-EPGKGTTFTVTLPLA 328
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
1013-1197 |
7.97e-31 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 121.94 E-value: 7.97e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1013 DEIARELEHLRKNVDHIKEVVAMQQsyAKVAGVAESMPLTDVVDDALRMYELELARHQITLDRDYQAQ-PVLRTDRHKLM 1091
Cdd:COG2205 57 EIIRESAERLLRLIEDLLDLSRLES--GKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPElPLVYADPELLE 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1092 QILVNLIQNA-KYAckesnRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGY----TTRKDGHGFGLhsgAL 1166
Cdd:COG2205 135 QVLANLLDNAiKYS-----PPGGTITISARREGDGVRISVSDNGPGIPEEELERIFERFYrgdnSRGEGGTGLGL---AI 206
|
170 180 190
....*....|....*....|....*....|....
gi 177841171 1167 V---AKELGGSLTAESGGaGEGATFTVELPLQAS 1197
Cdd:COG2205 207 VkriVEAHGGTIWVESEP-GGGTTFTVTLPLAES 239
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
775-1203 |
1.67e-28 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 121.23 E-value: 1.67e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 775 RDLLETKVTErtAELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSDVRAALA 854
Cdd:COG5809 124 RDITERKRME--EALRESEEKFRLIFNHSPDGIIVTDLDGRIIYANPAACKLLGISIE-ELIGKSILELIHSDDQENVAA 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 855 GEQEIIRTGQPLIGQVEVESEQaGNKRWLLTSKMPLrNKAGEIIGTFGISKDITMLKEAEaklieahRQLLVTSRQAGMA 934
Cdd:COG5809 201 FISQLLKDGGIAQGEVRFWTKD-GRWRLLEASGAPI-KKNGEVDGIVIIFRDITERKKLE-------ELLRKSEKLSVVG 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 935 EVATSVLHNVGNVLNSVNVSASLVSEKMRNARLDHLEkavAMLQAhaGDLAEFLVSdpkgrklpEFFALlssqltAERDE 1014
Cdd:COG5809 272 ELAAGIAHEIRNPLTSLKGFIQLLKDTIDEEQKTYLD---IMLSE--LDRIESIIS--------EFLVL------AKPQA 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1015 IARElehlRKNVDHI-KEVVAMQQSYAKvagvaesmpLTDVvddalrmyelelarhQITLDRDYQAQPVLrTDRHKLMQI 1093
Cdd:COG5809 333 IKYE----PKDLNTLiEEVIPLLQPQAL---------LKNV---------------QIELELEDDIPDIL-GDENQLKQV 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1094 LVNLIQNAKYACKEsnrpDRKIILRVT-QADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLHSGALVAKELG 1172
Cdd:COG5809 384 FINLLKNAIEAMPE----GGNITIETKaEDDDKVVISVTDEGCGIPEERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHG 459
|
410 420 430
....*....|....*....|....*....|.
gi 177841171 1173 GSLTAESgGAGEGATFTVELPLQASAGQESS 1203
Cdd:COG5809 460 GKITVES-EVGKGTTFSITLPIKLSEQVSMN 489
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
1015-1197 |
3.75e-26 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 112.34 E-value: 3.75e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1015 IARELEHLRKNVDHIKEVVAMQQSYAKVAgvAESMPLTDVVDDALRMYELELARHQITLDRDYQAQPV-LRTDRHKLMQI 1093
Cdd:COG5002 208 ILEEAERLSRLVNDLLDLSRLESGELKLE--KEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLlVLGDPDRLEQV 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1094 LVNLIQNA-KYackesNRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIF------AHGYTTRKDGHGFGLhsgAL 1166
Cdd:COG5002 286 LTNLLDNAiKY-----TPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFerfyrvDKSRSRETGGTGLGL---AI 357
|
170 180 190
....*....|....*....|....*....|....*
gi 177841171 1167 VaKEL----GGSLTAESgGAGEGATFTVELPLQAS 1197
Cdd:COG5002 358 V-KHIveahGGRIWVES-EPGKGTTFTITLPLARE 390
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
777-1195 |
1.18e-25 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 110.71 E-value: 1.18e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 777 LLETKVTERTAELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSssgaLIGRSDAELMpdsdvraalage 856
Cdd:COG3290 67 LLAALLLKLLEEIARLVEEREAVLESIREGVIAVDRDGRITLINDAARRLLGLD----AIGRPIDEVL------------ 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 857 QEIIRTGQpligqveVESEQAGNKRWLLTSKMPLRNKaGEIIGTFGISKDITMLKEAEAKLIEAHRQLLVTSRQAgmaev 936
Cdd:COG3290 131 AEVLETGE-------RDEEILLNGRVLVVNRVPIRDD-GRVVGAVATFRDRTELERLEEELEGVKELAEALRAQR----- 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 937 atsvlHNVGNVLNSVnvsASLVSekmrnarLDHLEKAVAMLQahagdlaeflvsdpkgrklpeffallssQLTAERDEIA 1016
Cdd:COG3290 198 -----HDFRNHLHTI---SGLLQ-------LGEYDEALEYID----------------------------EISEELQELI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1017 RELehlrknVDHIKEVVAmqqsyakvagvaesmpltdvvdDALRMYELELAR-HQITLDRDYQAQ-PVLRTDRHKLMQIL 1094
Cdd:COG3290 235 DSL------LSRIGNPVL----------------------AALLLGKAARAReRGIDLTIDIDSDlPDLPLSDTDLVTIL 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1095 VNLIQNAKYACKESNRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTT-RKDGHGFGLHSGALVAKELGG 1173
Cdd:COG3290 287 GNLLDNAIEAVEKLPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTkLGEGRGLGLALVKQIVEKYGG 366
|
410 420
....*....|....*....|..
gi 177841171 1174 SLTAESGGaGEGATFTVELPLQ 1195
Cdd:COG3290 367 TIEVESEE-GEGTVFTVRLPKE 387
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
1085-1195 |
1.36e-23 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 96.56 E-value: 1.36e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1085 TDRHKLMQILVNLIQNA-KYAckesnRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKD-----GHG 1158
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAiKYT-----PEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRsrkigGTG 75
|
90 100 110
....*....|....*....|....*....|....*..
gi 177841171 1159 FGLHSGALVAKELGGSLTAESgGAGEGATFTVELPLQ 1195
Cdd:smart00387 76 LGLSIVKKLVELHGGEISVES-EPGGGTTFTITLPLE 111
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
722-1197 |
8.82e-23 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 103.71 E-value: 8.82e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 722 TTGAELSFRLLPPFHETGWFYALCGLVSLAAVVGGHRWRVRHMEVARLKLQAERDLLETKVTERTAELAHEHALLTTLLD 801
Cdd:COG4251 27 VLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALLLVLLLLLAL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 802 SSPDQIYFKDTESRYLKASQARAEALGLSSSGALIGRSDAELMPDSDVRAALAGEQEIIRTGQPLIGQVEVESEQAGNKR 881
Cdd:COG4251 107 LLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 882 WLLTSKMPLRNKAGEIIGTFGISKDITMLKEAEAKLIEAHRQLLVTSRQAGMAEVATSVLHNVGNVLNSVNVSASLVSEK 961
Cdd:COG4251 187 VLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEE 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 962 MRNARLDHLEKAVAMLQ------AHagDLAEFLvsdpkgRKLPEFFALLSSQLTAERDEIARE-LEHLRKNVDHikevva 1034
Cdd:COG4251 267 ELEERTAELERSNEELEqfayvaSH--DLREPL------RKISGFSQLLEEDYGDKLDEEGREyLERIRDAAER------ 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1035 MQQ------SYAKVAGVA---ESMPLTDVVDDALRMYELELARHQITLDrdYQAQPVLRTDRHKLMQILVNLIQNA-KYa 1104
Cdd:COG4251 333 MQAliddllAYSRVGRQElefEPVDLNELLEEVLEDLEPRIEERGAEIE--VGPLPTVRGDPTLLRQVFQNLISNAiKY- 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1105 ckesNRPDR--KIILRVTQADGRARVAVVDNGIGIPRESLSRIFA-----HGyTTRKDGHGFGLhsgALVAK---ELGGS 1174
Cdd:COG4251 410 ----SRPGEppRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEifqrlHS-RDEYEGTGIGL---AIVKKiveRHGGR 481
|
490 500
....*....|....*....|...
gi 177841171 1175 LTAESgGAGEGATFTVELPLQAS 1197
Cdd:COG4251 482 IWVES-EPGEGATFYFTLPKAPA 503
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
798-1200 |
6.40e-20 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 95.42 E-value: 6.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 798 TLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMP-DSD----VRAALAGEQEIIrtgqpligQVEV 872
Cdd:PRK11360 266 LILESIADGVIAIDRQGKITTMNPAAEVITGLQRH-ELVGKPYSELFPpNTPfaspLLDTLEHGTEHV--------DLEI 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 873 ESEQAGNKRWLLTSKMPLRNKAGEIIGTFGISKDITMLKEAEAKLieaHRQllvtSRQAGMAEVATSVLHNVGNVLNSVN 952
Cdd:PRK11360 337 SFPGRDRTIELSVSTSLLHNTHGEMIGALVIFSDLTERKRLQRRV---ARQ----ERLAALGELVAGVAHEIRNPLTAIR 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 953 VSAslvsekmrnarldhlekavamlqahagdlaEFLVSDPKGRKLPEFFALlssqltaerdeIARELEHLRKNVDHIKEV 1032
Cdd:PRK11360 410 GYV------------------------------QIWRQQTSDPPSQEYLSV-----------VLREVDRLNKVIDQLLEF 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1033 VAMQQSY-AKVAgvaesmpLTDVVDDALRMYELELARHQITLDRDYQAQ-PVLRTDRHKLMQILVNLIQNAKYACKESNR 1110
Cdd:PRK11360 449 SRPRESQwQPVS-------LNALVEEVLQLFQTAGVQARVDFETELDNElPPIWADPELLKQVLLNILINAVQAISARGK 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1111 pdrkiiLRVT---QADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLHsgalVAKEL----GGSLTAESgGAG 1183
Cdd:PRK11360 522 ------IRIRtwqYSDGQVAVSIEDNGCGIDPELLKKIFDPFFTTKAKGTGLGLA----LSQRIinahGGDIEVES-EPG 590
|
410
....*....|....*..
gi 177841171 1184 EGATFTVELPLQASAGQ 1200
Cdd:PRK11360 591 VGTTFTLYLPINPQGNQ 607
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
1090-1192 |
8.74e-20 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 85.35 E-value: 8.74e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNA-KYAckesnRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKD----GHGFGLHSG 1164
Cdd:cd00075 1 LEQVLSNLLDNAlKYS-----PPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSreggGTGLGLAIV 75
|
90 100
....*....|....*....|....*...
gi 177841171 1165 ALVAKELGGSLTAESgGAGEGATFTVEL 1192
Cdd:cd00075 76 RRIVEAHGGRITVES-EPGGGTTFTVTL 102
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
1051-1197 |
9.55e-19 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 90.58 E-value: 9.55e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1051 LTDVVDDALRMYELELARHQITLDRDYQAQPVL-RTDRHKLMQILVNLIQNAKYACKESNrpdrKIILRVTQADGRARVA 1129
Cdd:COG5808 312 LNELIEEILSIIDSEANLKNIRVEKQSLDEPLHiKCDKDRIKQVLLNLIKNAIEAMKEGG----KLTISIENDDEKAVIE 387
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 177841171 1130 VVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLHSGALVAKELGGSLTAESgGAGEGATFTVELPLQAS 1197
Cdd:COG5808 388 VIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIES-EEGKGTTFTIRLPLKKE 454
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
768-1205 |
3.02e-18 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 90.77 E-value: 3.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 768 RLKLQAER----DLLETKVTERTA---ELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSGaLIGRSD 840
Cdd:PRK11091 122 REKAEEARqeafEQLKNEIKEREEtqiELEQQSSLLRSFLDASPDLVYYRNEDGEFSGCNRAMELLTGKSEKQ-LIGLTP 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 841 AELMPDSDVRAALAGEQEIIRTGQPLIgqveveSEQ-----AGNKRWLLTSKMPLRNKAGEIIGTFGISKDITMLKEAEA 915
Cdd:PRK11091 201 KDVYSPEAAEKVIETDEKVFRHNVSLT------YEQwldypDGRKACFELRKVPFYDRVGKRHGLMGFGRDITERKRYQD 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 916 KLIEAHRqllvtsrqagmaEVAT---SVLHNVGNVLNSVnVSASlvseKMrnarldhlekavamlqahagdlaeflvsdp 992
Cdd:PRK11091 275 ALEKASR------------DKTTfisTISHELRTPLNGI-VGLS----RI------------------------------ 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 993 kgrklpeffaLLSSQLTAErdeiarelehlrknvdhikevvamQQSYAK---VAGVAESMPLTDVVD-DALRMYELELAR 1068
Cdd:PRK11091 308 ----------LLDTELTAE------------------------QRKYLKtihVSAITLGNIFNDIIDmDKMERRKLQLDN 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1069 HQITLdRDY----------QAQPV-LR--------------TDRHKLMQILVNLIQNAKYACKESnrpdrKIILRVtQAD 1123
Cdd:PRK11091 354 QPIDF-TDFladlenlsglQAEQKgLRfdlepllplphkviTDGTRLRQILWNLISNAVKFTQQG-----GVTVRV-RYE 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1124 GRARVA--VVDNGIGIPRESLSRIFAHGYTTrKDGHGfGLHS-----GALVAKEL----GGSLTAESgGAGEGATFTVEL 1192
Cdd:PRK11091 427 EGDMLTfeVEDSGIGIPEDELDKIFAMYYQV-KDSHG-GKPAtgtgiGLAVSKRLaqamGGDITVTS-EEGKGSCFTLTI 503
|
490
....*....|...
gi 177841171 1193 PLQASAGQESSPP 1205
Cdd:PRK11091 504 HAPAVAEEVEDAF 516
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
1085-1195 |
4.27e-18 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 80.88 E-value: 4.27e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1085 TDRHKLMQILVNLIQNA-KYACKESnrpdrKIILRVTQaDGRARVAVVDNGIGIPRESLSRIFAHGYTTRKD---GHGFG 1160
Cdd:pfam02518 1 GDELRLRQVLSNLLDNAlKHAAKAG-----EITVTLSE-GGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRgggGTGLG 74
|
90 100 110
....*....|....*....|....*....|....*
gi 177841171 1161 LHSGALVAKELGGSLTAESgGAGEGATFTVELPLQ 1195
Cdd:pfam02518 75 LSIVRKLVELLGGTITVES-EPGGGTTVTLTLPLA 108
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
784-936 |
1.09e-17 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 84.31 E-value: 1.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 784 ERTAELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSDVRAALAGEQEIIRTG 863
Cdd:COG2202 1 TAEEALEESERRLRALVESSPDAIIITDLDGRILYVNPAFERLTGYSAE-ELLGKTLRDLLPPEDDDEFLELLRAALAGG 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 177841171 864 QPLIGQVEVESEQaGNKRWLLTSKMPLRNKAGEIIGTFGISKDITMLKEAEAKLIEAHRQL--LVTSRQAGMAEV 936
Cdd:COG2202 80 GVWRGELRNRRKD-GSLFWVELSISPVRDEDGEITGFVGIARDITERKRAEEALRESEERLrlLVENAPDGIFVL 153
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1193 |
1.55e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 76.28 E-value: 1.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNAKYACKESNRPDRKIILRVTQADGRA-RVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLHSGALVA 1168
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGGCERRELTIRTSPADDRAvTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSII 80
|
90 100
....*....|....*....|....*
gi 177841171 1169 KELGGSLTAESGGAGeGATFTVELP 1193
Cdd:cd16920 81 EAHGGRLSVESPAGG-GATFQFTLP 104
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
1088-1196 |
5.00e-15 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 79.57 E-value: 5.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1088 HKLMQILVNLIQNAKYACkeSNRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLhsgALV 1167
Cdd:PRK11086 432 HELITILGNLIENALEAV--GGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGL---YLV 506
|
90 100 110
....*....|....*....|....*....|..
gi 177841171 1168 ---AKELGGSLTAESgGAGEGATFTVELPLQA 1196
Cdd:PRK11086 507 kqsVENLGGSIAVES-EPGVGTQFFVQIPWDG 537
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
1016-1209 |
5.13e-15 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 80.11 E-value: 5.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1016 ARELEHLRKNVDHIKEVVAMQQSY-AKVAGVAESMPLTDVVDDALRMYELELARHqITLDRDYQAQPVLRT-DRHKLMQI 1093
Cdd:PRK13837 486 ARYIDEIISAGARARLIIDQILAFgRKGERNTKPFDLSELVTEIAPLLRVSLPPG-VELDFDQDQEPAVVEgNPAELQQV 564
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1094 LVNLIQNAKYACKESNRpdrkIILRVTQADGRA---------------RVAVVDNGIGIPRESLSRIFAHGYTTRKDGHG 1158
Cdd:PRK13837 565 LMNLCSNAAQAMDGAGR----VDISLSRAKLRApkvlshgvlppgryvLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTG 640
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 177841171 1159 FGLHSGALVAKELGGSLTAESgGAGEGATFTVELPLqasagqeSSPPPAAS 1209
Cdd:PRK13837 641 LGLATVHGIVSAHAGYIDVQS-TVGRGTRFDVYLPP-------SSKVPVAP 683
|
|
| PAS_4 |
pfam08448 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
800-912 |
6.35e-15 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain is associated to signalling systems and works as a signal sensor domain. It recognizes differently substituted aromatic hydrocarbons, oxygen, different dodecanoic acids, autoinducers, 3,5-dimethyl-pyrazin-2-ol and N-alanyl-aminoacetone (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 312075 [Multi-domain] Cd Length: 110 Bit Score: 72.06 E-value: 6.35e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 800 LDSSPDQIYFKDTESRYLKASQARAEALGLSSsGALIGRSDAELMPDSDVRAALAGEQEIIRTGQPLIGQVEVESEqaGN 879
Cdd:pfam08448 1 LDSLPDALAVLDPDGRVRYANAAAAELFGLPP-EELLGKTLAELLPPEDAARLERALRRALEGEEPIDFLEELLLN--GE 77
|
90 100 110
....*....|....*....|....*....|...
gi 177841171 880 KRWLLTSKMPLRNKAGEIIGTFGISKDITMLKE 912
Cdd:pfam08448 78 ERHYELRLTPLRDPDGEVIGVLVISRDITERRR 110
|
|
| Y_Y_Y |
pfam07495 |
Y_Y_Y domain; This domain is mostly found at the end of the beta propellers (pfam07494) in a ... |
668-732 |
6.56e-15 |
|
Y_Y_Y domain; This domain is mostly found at the end of the beta propellers (pfam07494) in a family of two component regulators. However they are also found tandemly repeated in Swiss:Q891H4 without other signal conduction domains being present. It's named after the conserved tyrosines found in the alignment. The exact function is not known.
Pssm-ID: 400051 [Multi-domain] Cd Length: 65 Bit Score: 70.46 E-value: 6.56e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 177841171 668 SYIAPRKLRARYRLHGLEEEWVDAGPRRSALYSRLAPGNYTFQVQACNADGVWNTTGAELSFRLL 732
Cdd:pfam07495 1 NYDGPENLLYRYRLEGFDGEWVELGDYSEASYTNLPPGKYTLKVKAKDNDGNWSYDDASLNFTIL 65
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1087-1194 |
8.60e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 71.30 E-value: 8.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1087 RHKLMQILVNLIQNAKYACKESNRpdrkIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTR--KDGHGFGLHSG 1164
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGRGR----ITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKpvGEGTGLGLSLS 76
|
90 100 110
....*....|....*....|....*....|
gi 177841171 1165 ALVAKELGGSLTAESgGAGEGATFTVELPL 1194
Cdd:cd16943 77 YRIIQKHGGTIRVAS-VPGGGTRFTIILPI 105
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
1090-1194 |
3.06e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 69.83 E-value: 3.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNA-KYAckesnrPDRKIILRV-----TQADGRARVAVVDNGIGIPRESLSRIF-----AHGYTTRK-DGH 1157
Cdd:cd16922 1 LRQILLNLLGNAiKFT------EEGEVTLRVsleeeEEDGVQLRFSVEDTGIGIPEEQQARLFepfsqADSSTTRKyGGT 74
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 177841171 1158 GFGLhsgALV---AKELGGSLTAESGGaGEGATFTVELPL 1194
Cdd:cd16922 75 GLGL---AISkklVELMGGDISVESEP-GQGSTFTFTLPL 110
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1192 |
3.52e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 69.41 E-value: 3.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNAKYACKESNRPDRKIILRVtqADGRARVAVVDNGIGIPRESLSRIFAHGYTTRK--DGHGFGLHSGALV 1167
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENPRIRIAARR--LGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPvgKGTGLGLSISYGI 78
|
90 100
....*....|....*....|....*
gi 177841171 1168 AKELGGSLTAESGGAGeGATFTVEL 1192
Cdd:cd16976 79 VEEHGGRLSVANEEGA-GARFTFDL 102
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
49-283 |
8.25e-14 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 73.13 E-value: 8.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 49 DVVQTPDGFIWLGTQNG--LVRFD--GLEFKVVPItlpyAGGQDVAKLSIAPDGALWFAINRGG-FGRFDgqkfsPIDDA 123
Cdd:COG4257 21 DVAVDPDGAVWFTDQGGgrIGRLDpaTGEFTEYPL----GGGSGPHGIAVDPDGNLWFTDNGNNrIGRID-----PKTGE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 124 --RFQDPRIAAG--TILVGRDGAIWTgTVNGLNRWVKDRPAE------SFYAESVQPSGTVLalheDAAGRMWVG-TGGS 192
Cdd:COG4257 92 itTFALPGGGSNphGIAFDPDGNLWF-TDQGGNRIGRLDPATgevtefPLPTGGAGPYGIAV----DPDGNLWVTdFGAN 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 193 GLYY--HDGKSLHELRDESlRGYSTVALTSDARGAIWLA--TARSLRRLAPGAER-TEVLLTEMPVS--AVLVDRQGVVW 265
Cdd:COG4257 167 AIGRidPDTGTLTEYALPT-PGAGPRGLAVDPDGNLWVAdtGSGRIGRFDPKTGTvTEYPLPGGGARpyGVAVDGDGRVW 245
|
250 260
....*....|....*....|
gi 177841171 266 FGTTSRG-LGRYA-DGEFTF 283
Cdd:COG4257 246 FAESGANrIVRFDpDTELTE 265
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1193 |
1.00e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 68.47 E-value: 1.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNAKYACKESNRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDG-HGFGLHSGALVA 1168
Cdd:cd16915 1 LITIVGNLIDNALDALAATGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGeRGIGLALVRQSV 80
|
90 100
....*....|....*....|....*
gi 177841171 1169 KELGGSLTAESgGAGEGATFTVELP 1193
Cdd:cd16915 81 ERLGGSITVES-EPGGGTTFSIRIP 104
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1193 |
2.92e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 67.21 E-value: 2.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNAKyackeSNRPDR--KIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLHS--GA 1165
Cdd:cd16953 1 LGQVLRNLIGNAI-----SFSPPDtgRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGQHSglGL 75
|
90 100 110
....*....|....*....|....*....|....*
gi 177841171 1166 LVAKEL----GGSLTAES---GGAGEGATFTVELP 1193
Cdd:cd16953 76 SISRQIieahGGISVAENhnqPGQVIGARFTVQLP 110
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
782-917 |
3.26e-12 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 68.13 E-value: 3.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 782 VTERT---AELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSDVRAALAGEQE 858
Cdd:COG2202 122 ITERKraeEALRESEERLRLLVENAPDGIFVLDLDGRILYVNPAAEELLGYSPE-ELLGKSLLDLLHPEDRERLLELLRR 200
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 177841171 859 IIRTGQPlIGQVEVESEQAGNKRWLLTSKMPLRNKAGEIIGTFGISKDITMLKEAEAKL 917
Cdd:COG2202 201 LLEGGRE-SYELELRLKDGDGRWVWVEASAVPLRDGGEVIGVLGIVRDITERKRAEEAL 258
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
1047-1198 |
6.18e-12 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 70.44 E-value: 6.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1047 ESMPLTDVVDDALRMYELELARHQITLdRDYQAQPV---LRTDRHKLMQILVNLIQNakyACKESnrPDRKIILRVTQAD 1123
Cdd:PRK15347 469 EETALLPLLDQAMLTIQGPAQSKSLTL-RTFVGAHVplyLHLDSLRLRQILVNLLGN---AVKFT--ETGGIRLRVKRHE 542
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 177841171 1124 GRARVAVVDNGIGIPRESLSRIFA--HGYTTRKDGHGFGLHSGALVAKELGGSLTAESgGAGEGATFTVELPLQASA 1198
Cdd:PRK15347 543 QQLCFTVEDTGCGIDIQQQQQIFTpfYQADTHSQGTGLGLTIASSLAKMMGGELTLFS-TPGVGSCFSLVLPLNEYA 618
|
|
| RocR |
COG3829 |
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ... |
784-929 |
1.91e-11 |
|
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 443041 [Multi-domain] Cd Length: 448 Bit Score: 67.87 E-value: 1.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 784 ERTAELAHEHALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSDVRaalageqEIIRTG 863
Cdd:COG3829 1 AEELELKELEEELEAILDSLDDGIIVVDADGRITYVNRAAERILGLPRE-EVIGKNVTELIPNSPLL-------EVLKTG 72
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 177841171 864 QPLIGQVeveSEQAGNKRWLLTSKMPLRNKaGEIIGTFGISKDITMLKEAEAKLIEAHRQLLVTSR 929
Cdd:COG3829 73 KPVTGVI---QKTGGKGKTVIVTAIPIFED-GEVIGAVETFRDITELKRLERKLREEELERGLSAK 134
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1086-1182 |
3.01e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 61.40 E-value: 3.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1086 DRHKLMQILVNLIQNAKYACKEsnRPDRKIILRV---TQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLh 1162
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEG--RPSDVGEVRIrveADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGL- 77
|
90 100
....*....|....*....|....*.
gi 177841171 1163 sgALVAK---ELGGSLT---AESGGA 1182
Cdd:cd16944 78 --AIVKKimeEHGGRISlsnREAGGA 101
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1085-1193 |
6.60e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 60.38 E-value: 6.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1085 TDRHKLMQILVNLIQNA-KYACKESnrpdrKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTT---RKDGH--G 1158
Cdd:cd16948 1 TDAKWLSFIIGQIVSNAlKYSKQGG-----KIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGengRNFQEstG 75
|
90 100 110
....*....|....*....|....*....|....*
gi 177841171 1159 FGLHSGALVAKELGGSLTAESgGAGEGATFTVELP 1193
Cdd:cd16948 76 MGLYLVKKLCDKLGHKIDVES-EVGEGTTFTITFP 109
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
1047-1196 |
7.44e-11 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 66.60 E-value: 7.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1047 ESMPLTDVVDDALRMYELELARHQITLDRDyQAQPVLRTDRHKLMQILVNLIQNA-KYAckesnRPDRKIILRVTQADGR 1125
Cdd:PRK10490 737 EWLTLEEVVGSALQMLEPGLSGHPINLSLP-EPLTLIHVDGPLFERVLINLLENAvKYA-----GAQAEIGIDAHVEGER 810
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 177841171 1126 ARVAVVDNGIGIPRESLSRIFAHGYTTRKD----GHGFGLHSGALVAKELGGSLTAESGGAGeGATFTVELPLQA 1196
Cdd:PRK10490 811 LQLDVWDNGPGIPPGQEQLIFDKFARGNKEsaipGVGLGLAICRAIVEVHGGTIWAENRPEG-GACFRVTLPLET 884
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
1016-1196 |
9.41e-11 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 65.58 E-value: 9.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1016 AREL-EHLRKNVDHIKEVVAMQQSYAKVAGVA-ESMPLTDVVDDALRMYELELARHQITLD-RDYQAQPVLRTDRHKLMQ 1092
Cdd:PRK10364 272 AHQLaQVMAKEADRLNRVVSELLELVKPTHLAlQAVDLNDLINHSLQLVSQDANSREIQLRfTANDTLPEIQADPDRLTQ 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1093 ILVNLIQNAKYACKESNRpdrkIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGLHSGALVAKELG 1172
Cdd:PRK10364 352 VLLNLYLNAIQAIGQHGV----ISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHG 427
|
170 180
....*....|....*....|....
gi 177841171 1173 GSLTAESgGAGEGATFTVELPLQA 1196
Cdd:PRK10364 428 GTIQVAS-QEGKGATFTLWLPVNI 450
|
|
| sensory_box |
TIGR00229 |
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain ... |
794-917 |
3.18e-10 |
|
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain occupies the central portion of the PAS domain but is more widely distributed. It is often tandemly repeated. Known prosthetic groups bound in the S-box domain include heme in the oxygen sensor FixL, FAD in the redox potential sensor NifL, and a 4-hydroxycinnamyl chromophore in photoactive yellow protein. Proteins containing the domain often contain other regulatory domains such as response regulator or sensor histidine kinase domains. Other S-box proteins include phytochromes and the aryl hydrocarbon receptor nuclear translocator. [Regulatory functions, Small molecule interactions]
Pssm-ID: 272971 [Multi-domain] Cd Length: 124 Bit Score: 58.84 E-value: 3.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 794 ALLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSGaLIGRSDAELMPDSDvRAALAGEQEIIRTGQPLIGQVEVE 873
Cdd:TIGR00229 3 ERYRAIFESSPDAIIVIDLEGNILYVNPAFEEIFGYSAEE-LIGRNVLELIPEED-REEVRERIERRLEGEPEPVSEERR 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 177841171 874 SEQA-GNKRWLLTSKMPLRnKAGEIIGTFGISKDITMLKEAEAKL 917
Cdd:TIGR00229 81 VRRKdGSEIWVEVSVSPIR-TNGGELGVVGIVRDITERKEAEEAL 124
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1193 |
3.37e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 58.57 E-value: 3.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNAKYACKESnrpDRKIILR------VTQADGR----ARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGF 1159
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGS---GGEIILRtrtqrqVTLGHPRhrlaLRVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGL 77
|
90 100 110
....*....|....*....|....*....|....*
gi 177841171 1160 GLHSGALVAKELGGSLTAESggaGEGAT-FTVELP 1193
Cdd:cd16918 78 GLAIAQNIVSQHGGVIECDS---QPGHTvFSVSLP 109
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
961-1209 |
4.01e-10 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 64.54 E-value: 4.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 961 KMRNARLDHL--EKAVAMLQAHAGDLAE--FLVSDPKGRKLPEFFALLSSQLTAERDEIARELEHLRKNVDHIKEVVAMQ 1036
Cdd:PRK11466 417 KARTAELQELviEHRQARAEAEKASQAKsaFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTIL 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1037 QS---YAKVAGVAESMPLTD-------VVDDALRMYELELARHQITLDRDYQAQ--PVLRTDRHKLMQILVNLIQNAKYA 1104
Cdd:PRK11466 497 NDildYSAIEAGGKNVSVSDepfeprpLLESTLQLMSGRVKGRPIRLATDIADDlpTALMGDPRRIRQVITNLLSNALRF 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1105 CKESNrpdrkIILRVTQADGRARVAVVDNGIGIPRESLSRIFAH--GYTTRKDGHGFGLHSGALVAKELGGSLTAESgGA 1182
Cdd:PRK11466 577 TDEGS-----IVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPfvQVSGKRGGTGLGLTISSRLAQAMGGELSATS-TP 650
|
250 260
....*....|....*....|....*..
gi 177841171 1183 GEGATFTVELPLQASAgqesSPPPAAS 1209
Cdd:PRK11466 651 EVGSCFCLRLPLRVAT----APVPKTV 673
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
1007-1179 |
1.20e-09 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 62.40 E-value: 1.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1007 QLTAERDEIARE----LEHLRKNVDHIkeVVAMQQSYAKVAGVAESMPLTDVVDDALRMYELELARHQITL----DRDYQ 1078
Cdd:COG4192 461 ALEQENYAQLPTsldkIEGLIERMDKI--IKSLRQFSRKSDTPLQPVDLRQVIEQAWELVESRAKPQQITLhipdDLMVQ 538
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1079 AQPVLrtdrhkLMQILVNLIQNAKYACKESnrpdRKIILRVTQADGRARVAVVDNGIGIPreSLSRIFAHGYTTRKDGHG 1158
Cdd:COG4192 539 GDQVL------LEQVLVNLLVNALDAVATQ----PQISVDLLSNAENLRVAISDNGNGWP--LVDKLFTPFTTTKEVGLG 606
|
170 180
....*....|....*....|.
gi 177841171 1159 FGLHSGALVAKELGGSLTAES 1179
Cdd:COG4192 607 LGLSICRSIMQQFGGDLYLAS 627
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1053-1192 |
3.85e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 56.10 E-value: 3.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1053 DVVDDALRMYELELARHQITLDRDYQAQPVLRTDRHKLMQILVNLIQNAkyaCKESnrpDRKIILRVTQADGRARVAVVD 1132
Cdd:cd16954 1 PLLDSLCSALNKVYQRKGVSISLDISPELRFPGERNDLMELLGNLLDNA---CKWC---LEFVEVTARQTDGGLHLIVDD 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 177841171 1133 NGIGIPRESLSRIFAHGytTRKD----GHGFGLHSGALVAKELGGSLTAESGGAGeGATFTVEL 1192
Cdd:cd16954 75 DGPGVPESQRSKIFQRG--QRLDeqrpGQGLGLAIAKEIVEQYGGELSLSDSPLG-GARFEVVF 135
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
1057-1195 |
6.21e-09 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 59.65 E-value: 6.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1057 DALRMY-ELELARH------QITLDRDYQAQPVLRtdrhKLMQILVNliqNAKYACKESNRPDRKIILRVTQADGRARVA 1129
Cdd:COG2972 304 ELIKSYlEIQKLRFgdrlevEIEIDEELLDLLIPK----LILQPLVE---NAIEHGIEPKEGGGTIRISIRKEGDRLVIT 376
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 177841171 1130 VVDNGIGIPRESLSRIFAhGYTTRKDGHGFGLHSgalVAKEL------GGSLTAESgGAGEGATFTVELPLQ 1195
Cdd:COG2972 377 VEDNGVGMPEEKLEKLLE-ELSSKGEGRGIGLRN---VRERLklyygeEYGLEIES-EPGEGTTVTIRIPLE 443
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1193 |
1.01e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 54.26 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNA-KYackesNRPDRKIILRVTQAD--GRARVAVVDNGIGIPRESLSRIFA-----HGyttRKDGHGFGL 1161
Cdd:cd16921 1 LGQVLTNLLGNAiKF-----RRPRRPPRIEVGAEDvgEEWTFYVRDNGIGIDPEYAEKVFGifqrlHS---REEYEGTGV 72
|
90 100 110
....*....|....*....|....*....|....*.
gi 177841171 1162 hsGALVAKEL----GGSLTAESgGAGEGATFTVELP 1193
Cdd:cd16921 73 --GLAIVRKIierhGGRIWLES-EPGEGTTFYFTLP 105
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
737-1198 |
1.62e-08 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 58.76 E-value: 1.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 737 ETGWFYALCGLVSLAAVVGGHRWRVRHMEVARLKLQAERDLLETKVTERTAELAHEHALLTTLLDSSPDQIYFKDTESRY 816
Cdd:COG3920 108 AGLLLLAALLLLRLVALLAALALLALLLLLLLLLAILALAELAVALAELAAALLLLAEELAALRLAAAALLLLLAALLDL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 817 LKASQARAEALGLSSSGALIGRSDAELMPDSDVRAALAGEQEIIRTGQPLIGQVEVESEQAGNKRWLLTSKMPLRNKAGE 896
Cdd:COG3920 188 GLALAALAAAALLALLLALELLLALLLLLLLLLALLLVLLAALLRLRAAVLEELERRRRARGLGRLLLLLLLLLLLLRAL 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 897 IIGTFGISKDITMLKEAEAKLIEAHRQllvtsRQAGMAEVAtsvlHNVGNVLNSVnvsASLVSEKMRNARldhlekavam 976
Cdd:COG3920 268 LLLAAGIRLVITERKRAEEELEASLEE-----KELLLRELH----HRVKNNLQVV---SSLLRLQARRAD---------- 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 977 lqahagdlaeflvsDPKGRklpEFFALLSSQLTAerdeIARELEHLRKNVDhikevvamqqsyakvagvAESMPLTDVVD 1056
Cdd:COG3920 326 --------------DPEAR---EALEESQNRIQA----LALVHELLYQSED------------------WEGVDLRDYLR 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1057 DALRMYELELARHQITLDRDY--------QAQPVLrtdrhklmqILVN-LIQNA-KYACKEsnRPDRKIILRVTQADGRA 1126
Cdd:COG3920 367 ELLEPLRDSYGGRGIRIELDGpdvelpadAAVPLG---------LILNeLVTNAlKHAFLS--GEGGRIRVSWRREDGRL 435
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 177841171 1127 RVAVVDNGIGIPREslsrifahgyTTRKDGHGFGLhsgALV---AKELGGSLTAESggaGEGATFTVELPLQASA 1198
Cdd:COG3920 436 RLTVSDNGVGLPED----------VDPPARKGLGL---RLIralVRQLGGTLELDR---PEGTRVRITFPLAELA 494
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
847-1211 |
6.06e-08 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 56.99 E-value: 6.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 847 SDVRAALAGEQEIirtgqpligQVEV-ESEQAGNKRW--LLTSkmPLRNKAGEIIGTFGISKDITMLKEAEAKLIEAHRQ 923
Cdd:PRK13557 92 AEVRDAIAERREI---------ATEIlNYRKDGSSFWnaLFVS--PVYNDAGDLVYFFGSQLDVSRRRDAEDALRQAQKM 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 924 LLVTSRQAGMAevatsvlHNVGNVLNSVnvsaslvsekmrnarLDHLEKAVAMLQAHAGDLAEFLVSDPKGRKLPEFFAL 1003
Cdd:PRK13557 161 EALGQLTGGIA-------HDFNNLLQVM---------------SGYLDVIQAALSHPDADRGRMARSVENIRAAAERAAT 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1004 LSSQLTAerdeIARElEHLRKNVDHIKevvamqqsyakvaGVAESMPltdvvddalrmyelELARH----QITLDRDYQa 1079
Cdd:PRK13557 219 LTQQLLA----FARK-QRLEGRVLNLN-------------GLVSGMG--------------ELAERtlgdAVTIETDLA- 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1080 qPVL---RTDRHKLMQILVNLIQNAKYAC------------KESNRPDRKIILRVtqADGR-ARVAVVDNGIGIPRESLS 1143
Cdd:PRK13557 266 -PDLwncRIDPTQAEVALLNVLINARDAMpeggrvtirtrnVEIEDEDLAMYHGL--PPGRyVSIAVTDTGSGMPPEILA 342
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 177841171 1144 RIFAHGYTTRKDGHGFGLhsG-ALV---AKELGGSLTAESgGAGEGATFTVELPlqASAGQESSPPPAASIS 1211
Cdd:PRK13557 343 RVMDPFFTTKEEGKGTGL--GlSMVygfAKQSGGAVRIYS-EVGEGTTVRLYFP--ASDQAENPEQEPKARA 409
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
1047-1194 |
4.04e-07 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 54.08 E-value: 4.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1047 ESMPLTDVVDDALRMYELELARHQITLDrdYQAQPV-LRTDRHKLMQILVNLIQNAKYACKESNRpdrkIILRVTQADGR 1125
Cdd:PRK11100 327 EPVALAALLEELVEAREAQAAAKGITLR--LRPDDArVLGDPFLLRQALGNLLDNAIDFSPEGGT----ITLSAEVDGEQ 400
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 177841171 1126 ARVAVVDNGIGIPRESLSRIFAHGYTT-RKDGH----GFGLHSGALVAKELGGSLTAESgGAGEGATFTVELPL 1194
Cdd:PRK11100 401 VALSVEDQGPGIPDYALPRIFERFYSLpRPANGrkstGLGLAFVREVARLHGGEVTLRN-RPEGGVLATLTLPR 473
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1086-1193 |
4.87e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 49.38 E-value: 4.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1086 DRHKLMQILVNLIQNA-KYAckesnRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGY---TTRK---DGHG 1158
Cdd:cd16946 1 DRDRLQQLFVNLLENSlRYT-----DTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYrveSSRNrasGGSG 75
|
90 100 110
....*....|....*....|....*....|....*
gi 177841171 1159 FGLHSGALVAKELGGSLTAESGGAGeGATFTVELP 1193
Cdd:cd16946 76 LGLAICHNIALAHGGTISAEHSPLG-GLRLVLTLP 109
|
|
| HATPase_AgrC-ComD-like |
cd16935 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1057-1192 |
9.37e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.
Pssm-ID: 340412 [Multi-domain] Cd Length: 134 Bit Score: 49.11 E-value: 9.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1057 DALRMYELELAR-HQITLD---RDYQAQPVLRTDrhkLMQILVNLIQNAKYACKESNRPDRKIILRVTQADGRArVAVVD 1132
Cdd:cd16935 3 DSLLSEKLELAReKGIEFTieiDIPILLPISPLD---LCIIFGNLLDNAIEACAKIDKENRFIHLKIRQKKGFL-IISIE 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 177841171 1133 NGIgipRESLSRIFAHGYTTRKD-GHGFGLHSGALVAKELGGSLTAESggagEGATFTVEL 1192
Cdd:cd16935 79 NSY---EGELKKKNGLFLSTKKDkNHGIGLKSIREIVKKYNGNLSIEY----ENGIFTLSI 132
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
1090-1193 |
9.63e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 48.92 E-value: 9.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNAKYACKESNRPDRKIILRVTQADGRAR-----------VAVVDNGIGIPRESLSRIFAHGYTTRKDGHG 1158
Cdd:cd16919 1 LELAILNLAVNARDAMPEGGRLTIETSNQRVDADYALNyrdlipgnyvcLEVSDTGSGMPAEVLRRAFEPFFTTKEVGKG 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 177841171 1159 FGLHSGAL--VAKELGGSLTAESgGAGEGATFTVELP 1193
Cdd:cd16919 81 TGLGLSMVygFVKQSGGHLRIYS-EPGVGTTVRIYLP 116
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
1043-1206 |
1.14e-06 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 52.93 E-value: 1.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1043 AG--VAESMP--LTDVVDDALRMY-------ELELarhqiTLDRDYQAQPVLRTDRHKLMQILVNLIQNA-KYAckESNR 1110
Cdd:PRK11107 356 AGklVLENIPfsLRETLDEVVTLLahsahekGLEL-----TLNIDPDVPDNVIGDPLRLQQIITNLVGNAiKFT--ESGN 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1111 PDRKIILRvTQADGRA--RVAVVDNGIGIPRESLSRIF-----AHGYTTRKDGhGFGLhsgALV-----AKELGGSLTAE 1178
Cdd:PRK11107 429 IDILVELR-ALSNTKVqlEVQIRDTGIGISERQQSQLFqafrqADASISRRHG-GTGL---GLVitqklVNEMGGDISFH 503
|
170 180
....*....|....*....|....*...
gi 177841171 1179 SGgAGEGATFTVELPLQASAGQESSPPP 1206
Cdd:PRK11107 504 SQ-PNRGSTFWFHLPLDLNPNPIIDGLP 530
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
1002-1197 |
1.00e-05 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 48.46 E-value: 1.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1002 ALLSSQLTAERDEIARELEHLRKNVDHIKEVV--AMQQSYAKVAGVAESMPLTDVVDDALRMYELELARH---QITLDRD 1076
Cdd:COG4585 70 SAIKLQLEAARRLLDADPEAAREELEEIRELAreALAELRRLVRGLRPPALDDLGLAAALEELAERLLRAagiRVELDVD 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1077 YQAQPVLRTDRHKLMQILVNLIQNA-KYAckesnrPDRKIILRVTQADGRARVAVVDNGIGIPRESLSrifahgyttrkd 1155
Cdd:COG4585 150 GDPDRLPPEVELALYRIVQEALTNAlKHA------GATRVTVTLEVDDGELTLTVRDDGVGFDPEAAP------------ 211
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 177841171 1156 GHGFGLHSGALVAKELGGSLTAESgGAGEGATFTVELPLQAS 1197
Cdd:COG4585 212 GGGLGLRGMRERAEALGGTLTIGS-APGGGTRVRATLPLAAA 252
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
1086-1193 |
1.33e-05 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 48.79 E-value: 1.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1086 DRHKLMQILVNLIQNA-KYAckesnrPD----RKIIL-RVTQadgRARVAVVDNGIGIPRESLSRIFAHGY----TTRKD 1155
Cdd:PRK09303 269 DQERIRQVLLNLLDNAiKYT------PEggtiTLSMLhRTTQ---KVQVSICDTGPGIPEEEQERIFEDRVrlprDEGTE 339
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 177841171 1156 GHGFGL---------HSGAL-VAKELggsltaesggaGEGATFTVELP 1193
Cdd:PRK09303 340 GYGIGLsvcrrivrvHYGQIwVDSEP-----------GQGSCFHFTLP 376
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
1054-1164 |
1.77e-05 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 48.54 E-value: 1.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1054 VVDDALRMYELELArHQITLDRDYQAQ-PVLRTDRHKLMQILVNLIQNAKYACKEsnrPDRKIILR---VTQAD--GR-- 1125
Cdd:PRK11073 202 VAERVVQLVSLELP-DNVRLIRDYDPSlPELAHDPDQIEQVLLNIVRNALQALGP---EGGTITLRtrtAFQLTlhGEry 277
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 177841171 1126 ---ARVAVVDNGIGIPRESLSRIFAHGYTTRKDGHGFGL---------HSG 1164
Cdd:PRK11073 278 rlaARIDIEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLsiarnlidqHSG 328
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
1066-1201 |
1.99e-05 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 48.48 E-value: 1.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1066 LARHQITLDRDYQAQPVLRTDRHKLMQILVNLIQNA-KYACKESnrpdrKIILRVTQADGRARVAVVDNGIGIPRESLSR 1144
Cdd:PRK10549 329 FASRGLTLQLSLPDSATVFGDPDRLMQLFNNLLENSlRYTDSGG-----SLHISAEQRDKTLRLTFADSAPGVSDEQLQK 403
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 177841171 1145 IFAHGYTTRKD------GHGFGLHSGALVAKELGGSLTAESGGAGeGATFTVELPLQASAGQE 1201
Cdd:PRK10549 404 LFERFYRTEGSrnrasgGSGLGLAICLNIVEAHNGRIIAAHSPFG-GVSITVELPLERDLQRE 465
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
1086-1193 |
4.56e-05 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 44.02 E-value: 4.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1086 DRHKLMQILVNLIQNAKYACKESNRPdrKIILRVTQAdGRARVAVVDNGIGIPRESLSRIFAH-----GYTTRKDGhGFG 1160
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRI--RCILEKFRL-NRFLLTVSDSGPGIPPNLREEIFERfrqgdGSSTRAHG-GTG 76
|
90 100 110
....*....|....*....|....*....|....*..
gi 177841171 1161 LhsGALVAKEL----GGSLTAeSGGAGEGATFTVELP 1193
Cdd:cd16925 77 L--GLSIVKEFvelhGGTVTV-SDAPGGGALFQVELP 110
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
1015-1161 |
6.13e-05 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 46.88 E-value: 6.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1015 IAReLEHLRKNVDHIKEVVAMQQSYAkvAGVAESMPLTDVVDDALR--MYELELARHQITLDRDYQAQPVLRTDRHKLMQ 1092
Cdd:PRK10755 174 IAR-LDQMMHTVEQLLQLARAGQSFS--SGHYQTVKLLEDVILPSQdeLSEMLEQRQQTLLLPESAADITVQGDATLLRL 250
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 177841171 1093 ILVNLIQNA-KYACKESNrpdrkIILRVTQADGRARVAVVDNGIGIP---RESLSRIFaHGYTTRKDGHGFGL 1161
Cdd:PRK10755 251 LLRNLVENAhRYSPEGST-----ITIKLSQEDGGAVLAVEDEGPGIDeskCGELSKAF-VRMDSRYGGIGLGL 317
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1194 |
1.09e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 42.42 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNA-KYAckesnrpDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFA------HGYTTRKDGHGFGLH 1162
Cdd:cd16939 1 MARALDNLLRNAlRYA-------HRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEpfvrldPSRDRATGGFGLGLA 73
|
90 100 110
....*....|....*....|....*....|..
gi 177841171 1163 SGALVAKELGGSLTAESGGAGeGATFTVELPL 1194
Cdd:cd16939 74 IVHRVALWHGGHVECDDSELG-GACFRLTWPR 104
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1086-1192 |
1.13e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 43.27 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1086 DRHKLMQILVNLIQNA-KYAckesnrPDRKIiLRVTQADGRARVA--VVDNGIGIPRESLSRIFAHGYT------TRKDG 1156
Cdd:cd16947 17 NTEALQRILKNLISNAiKYG------SDGKF-LGMTLREDEKHVYidIWDKGKGISETEKDHVFERLYTledsrnSAKQG 89
|
90 100 110
....*....|....*....|....*....|....*.
gi 177841171 1157 HGFGLHSGALVAKELGGSLTAESgGAGEGATFTVEL 1192
Cdd:cd16947 90 NGLGLTITKRLAESMGGSIYVNS-KPYEKTVFTVTL 124
|
|
| COG1389 |
COG1389 |
DNA topoisomerase VI, subunit B [Replication, recombination and repair]; |
1090-1147 |
1.62e-04 |
|
DNA topoisomerase VI, subunit B [Replication, recombination and repair];
Pssm-ID: 440999 [Multi-domain] Cd Length: 530 Bit Score: 45.59 E-value: 1.62e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 177841171 1090 LMQILVNLIQNAKYACKESNR-PDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFA 1147
Cdd:COG1389 36 LYTTVKEAVDNSLDACEEAGIlPDIKVSIERVDGKDIYRVTVEDNGPGIPPEQIPKVFG 94
|
|
| PAS |
pfam00989 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
798-907 |
1.81e-04 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain can bind gases (O2, CO and NO), FAD, 4-hydroxycinnamic acid and NAD+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395786 [Multi-domain] Cd Length: 113 Bit Score: 42.02 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 798 TLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSDVRAALAGEQEIIRTGQP-LIGQVEVESEQ 876
Cdd:pfam00989 5 AILESLPDGIFVVDEDGRILYVNAAAEELLGLSRE-EVIGKSLLDLIPEEDDAEVAELLRQALLQGEEsRGFEVSFRVPD 83
|
90 100 110
....*....|....*....|....*....|.
gi 177841171 877 aGNKRWLLTSKMPLRNKAGEIIGTFGISKDI 907
Cdd:pfam00989 84 -GRPRHVEVRASPVRDAGGEILGFLGVLRDI 113
|
|
| HATPase_PDK-like |
cd16929 |
Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain ... |
1050-1175 |
3.58e-04 |
|
Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of all four PDK isoforms (pyruvate dehydrogenase kinases 1-4) that have been described in mammals, and other PDKs including Saccharomyces Pkp1p and Pkp2p. PDKs and phosphatases tightly regulate the mitochondrial pyruvate dehydrogenase complex (PDC) by reversible phosphorylation. PDC catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA, connecting glycolysis and the TCA acid cycle. Also included in this family is mammalian branched-chain alpha-ketoacid dehydrogenase kinase (BDK), a mitochondrial protein kinase that phosphorylates a subunit of the branched-chain a-ketoacid dehydrogenase (BCKD) complex, which catalyzes the oxidative decarboxylation of branched-chain alpha-ketoacids derived from leucine, isoleucine, and valine, a rate-limiting step in the oxidative degradation of these branched-chain amino acids.
Pssm-ID: 340406 [Multi-domain] Cd Length: 169 Bit Score: 42.71 E-value: 3.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1050 PLTDVVDDALrmyelELARHQItlDRDYQAQPVLRTDRHK----------LMQILVNLIQNAKYACKES------NRPDR 1113
Cdd:cd16929 1 SPKKVVEDAS-----EEARVLC--DDYYLSSPELEIEGDPsirfpyvpshLYYILFELLKNAMRATVEShgddsdDLPPI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1114 KIILRVTQADgrARVAVVDNGIGIPRESLSRIFAHGYTTRKD-------------------GHGFGLHSGALVAKELGGS 1174
Cdd:cd16929 74 KVTVAKGDED--LTIKISDRGGGIPREDLARLFSYMYSTAPQpslddfsdlisgtqpsplaGFGYGLPMSRLYAEYFGGD 151
|
.
gi 177841171 1175 L 1175
Cdd:cd16929 152 L 152
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
221-311 |
4.35e-04 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 43.73 E-value: 4.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 221 DARGAIWLA--TARSLRRLAPGAERTEV-LLTEMPVSAVLVDRQGVVWFGTTSRGLGRY--ADGEFTFL----GKAEGLA 291
Cdd:COG3386 16 DPDGRLYWVdiPGGRIHRYDPDGGAVEVfAEPSGRPNGLAFDPDGRLLVADHGRGLVRFdpADGEVTVLadeyGKPLNRP 95
|
90 100
....*....|....*....|
gi 177841171 292 SDNVFslfeDREGSLWVGTP 311
Cdd:COG3386 96 NDGVV----DPDGRLYFTDM 111
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1189 |
5.43e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 40.52 E-value: 5.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNAKYACkesnrPDRKIILRVTQADGR-ARVAVVDNGIGIPRESLSRIFAHGYT-----TRKDGHGFGLHS 1163
Cdd:cd16945 5 LRQAINNLLDNAIDFS-----PEGGLIALQLEADTEgIELLVFDEGSGIPDYALNRVFERFYSlprphSGQKSTGLGLAF 79
|
90 100
....*....|....*....|....*.
gi 177841171 1164 GALVAKELGGSLTAESGGAGEGATFT 1189
Cdd:cd16945 80 VQEVAQLHGGRITLRNRPDGVLAFLT 105
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
1094-1193 |
7.49e-04 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 41.80 E-value: 7.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1094 LVNLIQNAKYACKESnRPDR---------KIILRVTQADGRARVAVVDNGIGIPRESLSR-------------------- 1144
Cdd:cd16916 43 LTHLLRNAVDHGIEA-PEERlaagkppegTITLRAEHQGNQVVIEVSDDGRGIDREKIREkaierglitadeaatlsdde 121
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 177841171 1145 ----IFAHGYTTRKD-----GHGFGLHSGALVAKELGGSLTAESgGAGEGATFTVELP 1193
Cdd:cd16916 122 vlnlIFAPGFSTAEQvtdvsGRGVGMDVVKRSIESLGGTIEVES-EPGQGTTFTIRLP 178
|
|
| PRK04184 |
PRK04184 |
DNA topoisomerase VI subunit B; Validated |
1090-1147 |
7.67e-04 |
|
DNA topoisomerase VI subunit B; Validated
Pssm-ID: 235246 [Multi-domain] Cd Length: 535 Bit Score: 43.73 E-value: 7.67e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNAKYACKESN-RPDRKI-ILRVTQADGRARVAVVDNGIGIPRESLSRIFA 1147
Cdd:PRK04184 37 LYTTVKELVDNSLDACEEAGiLPDIKIeIKRVDEGKDHYRVTVEDNGPGIPPEEIPKVFG 96
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1086-1180 |
7.96e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 40.47 E-value: 7.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1086 DRHKLMQILVNLIQNAKYACKESNRPDRKIilrvtQADGRARVAVVDNGIGIPRESLSRIFAHGYttRKD-----GHGFG 1160
Cdd:cd16940 10 DALLLFLLLRNLVDNAVRYSPQGSRVEIKL-----SADDGAVIRVEDNGPGIDEEELEALFERFY--RSDgqnygGSGLG 82
|
90 100
....*....|....*....|
gi 177841171 1161 LHSGALVAKELGGSLTAESG 1180
Cdd:cd16940 83 LSIVKRIVELHGGQIFLGNA 102
|
|
| PAS_9 |
pfam13426 |
PAS domain; This domain is found in many signalling proteins in which it functions as a sensor ... |
813-908 |
7.98e-04 |
|
PAS domain; This domain is found in many signalling proteins in which it functions as a sensor domain. It recognizes FMN, Zn(II), FAD and riboflavin (MAtilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 463873 [Multi-domain] Cd Length: 93 Bit Score: 39.75 E-value: 7.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 813 ESRYLKASQARAEALGLSSsGALIGRSDAELMPDSDVRAALAgeqEIIRTGQPLIGQVEVESEQAGNKRWLLTSKMPLRN 892
Cdd:pfam13426 1 DGRIIYVNDAALRLLGYTR-EELLGKSITDLFAEPEDSERLR---EALREGKAVREFEVVLYRKDGEPFPVLVSLAPIRD 76
|
90
....*....|....*.
gi 177841171 893 KAGEIIGTFGISKDIT 908
Cdd:pfam13426 77 DGGELVGIIAILRDIT 92
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
1086-1193 |
8.98e-04 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 43.28 E-value: 8.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1086 DRHKLMQILVNLIQNAKYACKESNRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTTRKDG---HGFGLH 1162
Cdd:PRK15053 429 DSTEFAAIVGNLLDNAFEASLRSDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEpgeHGIGLY 508
|
90 100 110
....*....|....*....|....*....|.
gi 177841171 1163 SGALVAKELGGSLTAESGGAgEGATFTVELP 1193
Cdd:PRK15053 509 LIASYVTRCGGVITLEDNDP-CGTLFSIFIP 538
|
|
| HATPase_TopVIB-like |
cd16933 |
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ... |
1090-1147 |
1.01e-03 |
|
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain] Cd Length: 203 Bit Score: 41.95 E-value: 1.01e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 177841171 1090 LMQILVNLIQNAKYACKESN-RPDRKIILRVTQADgRARVAVVDNGIGIPRESLSRIFA 1147
Cdd:cd16933 20 LYTTVRELVENSLDATEEAGiLPDIKVEIEEIGKD-HYKVIVEDNGPGIPEEQIPKVFG 77
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1193 |
1.11e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 39.74 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNA-KYAckesnrpdRKIILRVTQADG-RARVAVVDNGIGIPRESLSRI---FAHGYTTRK-DGHGFGLHS 1163
Cdd:cd16950 1 LKRVLSNLVDNAlRYG--------GGWVEVSSDGEGnRTRIQVLDNGPGIAPEEVDELfqpFYRGDNARGtSGTGLGLAI 72
|
90 100 110
....*....|....*....|....*....|
gi 177841171 1164 GALVAKELGGSLTAeSGGAGEGATFTVELP 1193
Cdd:cd16950 73 VQRISDAHGGSLTL-ANRAGGGLCARIELP 101
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1118-1193 |
1.15e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 39.07 E-value: 1.15e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 177841171 1118 RVTQADGRARVAVVDNGIGIPREslsrifahgytTRKDGHGFGLHSGALVAKELGGSLTAESgGAGEGATFTVELP 1193
Cdd:cd16917 24 TLSYTADELTLTVVDDGVGFDGP-----------APPGGGGFGLLGMRERAELLGGTLTIGS-RPGGGTRVTARLP 87
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
781-949 |
1.25e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 43.12 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 781 KVTERTAELAHehaLLTTLLDSSPDQIYFKDTESRYLKASQARAEALGLSSSgALIGRSDAELMPDSDVRAALAGEQEII 860
Cdd:PRK13560 194 RAEERIDEALH---FLQQLLDNIADPAFWKDEDAKVFGCNDAACLACGFRRE-EIIGMSIHDFAPAQPADDYQEADAAKF 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 861 RTgqPLIGQVEVESEQAGNKRW---LLTSKMPLRNKAGEIIGTFGISKDITMLKEAEAKLIEAHRQLLVTSRQAGMAEVA 937
Cdd:PRK13560 270 DA--DGSQIIEAEFQNKDGRTRpvdVIFNHAEFDDKENHCAGLVGAITDISGRRAAERELLEKEDMLRAIIEAAPIAAIG 347
|
170
....*....|..
gi 177841171 938 TSVLHNVGNVLN 949
Cdd:PRK13560 348 LDADGNICFVNN 359
|
|
| HATPase_c_5 |
pfam14501 |
GHKL domain; This family represents the structurally related ATPase domains of histidine ... |
1093-1192 |
1.35e-03 |
|
GHKL domain; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433996 [Multi-domain] Cd Length: 102 Bit Score: 39.51 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1093 ILVNLIQNAKYACKESNRPdRKIILRVTQaDGRARVAVVDNgigiPRESLSRIFAHGYTTRKDG--HGFGLHSGALVAKE 1170
Cdd:pfam14501 9 IFGNLLDNAIEACSKIDDN-RFIRLKIRE-KQNFLIIRIEN----TYEGELKFEGKLPSTKTKGdgHGIGLKSIRRIVKK 82
|
90 100
....*....|....*....|..
gi 177841171 1171 LGGSLTAESggagEGATFTVEL 1192
Cdd:pfam14501 83 YGGNLSTEI----ENGIFTLSI 100
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
1082-1195 |
1.50e-03 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 42.80 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1082 VLRTDRHKLMQILVNLIQNAKYACKESNRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGYTT----RKDGH 1157
Cdd:PRK09959 821 LVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTsagrQQTGS 900
|
90 100 110
....*....|....*....|....*....|....*...
gi 177841171 1158 GFGLHSGALVAKELGGSLTAESgGAGEGATFTVELPLQ 1195
Cdd:PRK09959 901 GLGLMICKELIKNMQGDLSLES-HPGIGTTFTITIPVE 937
|
|
| Reg_prop |
pfam07494 |
Two component regulator propeller; A large group of two component regulator proteins appear to ... |
289-310 |
1.56e-03 |
|
Two component regulator propeller; A large group of two component regulator proteins appear to have the same N-terminal structure of 14 tandem repeats. These repeats show homology to pfam01011 and pfam00400 indicating that they are likely to form a beta-propeller. This family has been built with artificially high cut-offs in order to avoid overlaps with other beta-propeller families. The fourteen repeats are likely to form two propellers; it is not clear if these structures are likely to recruit other proteins or interact with DNA.
Pssm-ID: 400050 [Multi-domain] Cd Length: 24 Bit Score: 36.91 E-value: 1.56e-03
|
| top6b |
TIGR01052 |
DNA topoisomerase VI, B subunit; This model describes DNA topoisomerase VI, an archaeal type ... |
1090-1146 |
1.62e-03 |
|
DNA topoisomerase VI, B subunit; This model describes DNA topoisomerase VI, an archaeal type II DNA topoisomerase (DNA gyrase). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273417 [Multi-domain] Cd Length: 488 Bit Score: 42.50 E-value: 1.62e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 177841171 1090 LMQILVNLIQNAKYACKESN-RPDRKIILRVTQADgRARVAVVDNGIGIPRESLSRIF 1146
Cdd:TIGR01052 29 LTTVIHELVTNSLDACEEAGiLPDIKVEIEKIGKD-HYKVTVEDNGPGIPEEYIPKVF 85
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
1069-1194 |
2.72e-03 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 41.51 E-value: 2.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1069 HQITLDRDYQAQPvLRTDRHKLMQILVNLIQNA-KYACKesnrpdrKIILRVTQADGRARVAVVDNGIGIPRESLSRIFA 1147
Cdd:PRK10604 300 KTVRLDTPHQGDY-GALDMRLMERVLDNLLNNAlRYAHS-------RVRVSLLLDGNQACLIVEDDGPGIPPEERERVFE 371
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 177841171 1148 HgyTTRKD--------GHGFGLHSGALVAKELGGSLTAESGGAGeGATFTVELPL 1194
Cdd:PRK10604 372 P--FVRLDpsrdratgGCGLGLAIVHSIALAMGGSVNCDESELG-GARFSFSWPV 423
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
1086-1162 |
4.26e-03 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 38.74 E-value: 4.26e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 177841171 1086 DRHKLMQILVNLIQNA-KYACKesNRPDRKIILRVTQADGRARVAVVDNGIGIPRESLsrifAHGYTTRKDGhGFGLH 1162
Cdd:COG2172 31 DADDLVLAVSEAVTNAvRHAYG--GDPDGPVEVELELDPDGLEIEVRDEGPGFDPEDL----PDPYSTLAEG-GRGLF 101
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1096-1193 |
4.98e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 37.95 E-value: 4.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1096 NLIQNA-KYAckesnRPDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGY------TTRKDGHGFGLHSGALVA 1168
Cdd:cd16952 7 NLVSNAvKYT-----PPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYrvdierCRNTGGTGLGLAIVKHVM 81
|
90 100
....*....|....*....|....*
gi 177841171 1169 KELGGSLTAESgGAGEGATFTVELP 1193
Cdd:cd16952 82 SRHDARLLIAS-ELGKGSRFTCLFP 105
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
1090-1194 |
5.39e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 37.69 E-value: 5.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177841171 1090 LMQILVNLIQNA-KYAckesnrpDRKIILRVTQADGRARVAVVDNGIGIPRESLSRIFAHGY------TTRKDGHGFGLH 1162
Cdd:cd16949 1 LARALENVLRNAlRYS-------PSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYrvdsarDRESGGTGLGLA 73
|
90 100 110
....*....|....*....|....*....|..
gi 177841171 1163 SGALVAKELGGSLTAESGGAGeGATFTVELPL 1194
Cdd:cd16949 74 IAERAIEQHGGKIKASNRKPG-GLRVRIWLPA 104
|
|
| |
