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Conserved domains on  [gi|171904065|gb|ACB56641|]
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MADS-box transcription factor APETALA1, partial [Eucalyptus occidentalis]

Protein Classification

MADS-box domain-containing protein( domain architecture ID 10210286)

MADS (MCM1, AGAMOUS, DEFICIENS, and SRF, serum response factor)-box domain-containing protein functions as a transcription factor and may be involved in various important aspects of development and differentiation

CATH:  3.40.1810.10
Gene Ontology:  GO:0003700|GO:0046983
PubMed:  29802068|12949148
SCOP:  4001594

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
K-box pfam01486
K-box region; The K-box region is commonly found associated with SRF-type transcription ...
 48-138 3.80e-31

K-box region; The K-box region is commonly found associated with SRF-type transcription factors see pfam00319. The K-box is a possible coiled-coil structure. Possible role in multimer formation.


:

Pssm-ID: 460228 [Multi-domain]  Cd Length: 91  Bit Score: 108.32  E-value: 3.80e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171904065   48 SETESIGSWTLEHAKLKARLEVLHRNYRHFMGKDLDSLSLKDLQNLEQQLESALKHIRSRKNQLMHESISALQKKDRALQ 127
Cdd:pfam01486   1 SEENEQENWQQEAAKLKKEIENLQRSQRQLLGEDLSSLSLKELQQLEQQLEKSLKRIRSRKNQLLLEQIEELKKKERILQ 80

                          90
                  ....*....|.
gi 171904065  128 EQNNLLTKKVK 138
Cdd:pfam01486  81 EENKELRKKLE 91
MADS super family cl00109
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ...
 1-44 1.14e-15

MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


The actual alignment was detected with superfamily member cd00265:

Pssm-ID: 469617 [Multi-domain]  Cd Length: 77  Bit Score: 67.96  E-value: 1.14e-15
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 171904065   1 SVLCDAEVALIIFSAKGKLFEYSTdSCMERILERYERYSYAEHQ 44
Cdd:cd00265   35 SVLCDAEVALIIFSSSGKLYEFSS-PSMEKIIERYQKTSGSSLW 77
 
Name Accession Description Interval E-value
K-box pfam01486
K-box region; The K-box region is commonly found associated with SRF-type transcription ...
 48-138 3.80e-31

K-box region; The K-box region is commonly found associated with SRF-type transcription factors see pfam00319. The K-box is a possible coiled-coil structure. Possible role in multimer formation.


Pssm-ID: 460228 [Multi-domain]  Cd Length: 91  Bit Score: 108.32  E-value: 3.80e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171904065   48 SETESIGSWTLEHAKLKARLEVLHRNYRHFMGKDLDSLSLKDLQNLEQQLESALKHIRSRKNQLMHESISALQKKDRALQ 127
Cdd:pfam01486   1 SEENEQENWQQEAAKLKKEIENLQRSQRQLLGEDLSSLSLKELQQLEQQLEKSLKRIRSRKNQLLLEQIEELKKKERILQ 80

                          90
                  ....*....|.
gi 171904065  128 EQNNLLTKKVK 138
Cdd:pfam01486  81 EENKELRKKLE 91
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 1-44 1.14e-15

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 67.96  E-value: 1.14e-15
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 171904065   1 SVLCDAEVALIIFSAKGKLFEYSTdSCMERILERYERYSYAEHQ 44
Cdd:cd00265   35 SVLCDAEVALIIFSSSGKLYEFSS-PSMEKIIERYQKTSGSSLW 77
MADS smart00432
MADS domain;
1-25 2.06e-08

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 48.71  E-value: 2.06e-08
                           10        20
                   ....*....|....*....|....*
gi 171904065     1 SVLCDAEVALIIFSAKGKLFEYSTD 25
Cdd:smart00432  35 SVLCDAEVALIVFSPTGKLYEFASP 59
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
1-22 8.85e-07

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 43.96  E-value: 8.85e-07
                          10        20
                  ....*....|....*....|..
gi 171904065    1 SVLCDAEVALIIFSAKGKLFEY 22
Cdd:pfam00319  27 SVLCGAEVAVIVFSPTGKLYTF 48
 
Name Accession Description Interval E-value
K-box pfam01486
K-box region; The K-box region is commonly found associated with SRF-type transcription ...
 48-138 3.80e-31

K-box region; The K-box region is commonly found associated with SRF-type transcription factors see pfam00319. The K-box is a possible coiled-coil structure. Possible role in multimer formation.


Pssm-ID: 460228 [Multi-domain]  Cd Length: 91  Bit Score: 108.32  E-value: 3.80e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171904065   48 SETESIGSWTLEHAKLKARLEVLHRNYRHFMGKDLDSLSLKDLQNLEQQLESALKHIRSRKNQLMHESISALQKKDRALQ 127
Cdd:pfam01486   1 SEENEQENWQQEAAKLKKEIENLQRSQRQLLGEDLSSLSLKELQQLEQQLEKSLKRIRSRKNQLLLEQIEELKKKERILQ 80

                          90
                  ....*....|.
gi 171904065  128 EQNNLLTKKVK 138
Cdd:pfam01486  81 EENKELRKKLE 91
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 1-44 1.14e-15

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 67.96  E-value: 1.14e-15
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 171904065   1 SVLCDAEVALIIFSAKGKLFEYSTdSCMERILERYERYSYAEHQ 44
Cdd:cd00265   35 SVLCDAEVALIIFSSSGKLYEFSS-PSMEKIIERYQKTSGSSLW 77
MADS smart00432
MADS domain;
1-25 2.06e-08

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 48.71  E-value: 2.06e-08
                           10        20
                   ....*....|....*....|....*
gi 171904065     1 SVLCDAEVALIIFSAKGKLFEYSTD 25
Cdd:smart00432  35 SVLCDAEVALIVFSPTGKLYEFASP 59
MADS cd00120
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ...
 1-24 3.86e-07

MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238067 [Multi-domain]  Cd Length: 59  Bit Score: 45.20  E-value: 3.86e-07
                         10        20
                 ....*....|....*....|....
gi 171904065   1 SVLCDAEVALIIFSAKGKLFEYST 24
Cdd:cd00120   35 SVLCDAEVAVIVFSPSGKLYEFWS 58
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
1-22 8.85e-07

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 43.96  E-value: 8.85e-07
                          10        20
                  ....*....|....*....|..
gi 171904065    1 SVLCDAEVALIIFSAKGKLFEY 22
Cdd:pfam00319  27 SVLCGAEVAVIVFSPTGKLYTF 48
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
 1-37 4.71e-06

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 43.02  E-value: 4.71e-06
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 171904065   1 SVLCDAEVALIIFSAKGKLFEYSTDSCMERILERYER 37
Cdd:cd00266   35 STLCGAEVAVIVYSPSGKLYVFWPSSEVEGVISRFEV 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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