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Conserved domains on  [gi|154519778|gb|ABS82771|]
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violaxanthin de-epoxidase, partial [Arbutus unedo]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Lipocalin super family cl21528
Lipocalin / cytosolic fatty-acid binding protein family; Lipocalins are transporters for small ...
 1-83 7.86e-16

Lipocalin / cytosolic fatty-acid binding protein family; Lipocalins are transporters for small hydrophobic molecules, such as lipids, steroid hormones, bilins, and retinoids. The family also encompasses the enzyme prostaglandin D synthase (EC:5.3.99.2). Alignment subsumes both the lipocalin and fatty acid binding protein signatures from PROSITE. This is supported on structural and functional grounds. The structure is an eight-stranded beta barrel.


The actual alignment was detected with superfamily member PLN02372:

Pssm-ID: 473899 [Multi-domain]  Cd Length: 455  Bit Score: 70.26  E-value: 7.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154519778   1 DFSGKWFITSGLNPTFDTFNCQRP*F*TE-SD**VGYW*RRILIPVG*LLSSG*L**H*LEIRTASLGYSY*GD*gdLHY 79
Cdd:PLN02372 205 DFNGRWYITSGLNKTFDTFDCQLHEFTAEdPDKLVGNLNWRINTPDGGFFTRSAVQRFVQDPNQPGILYNHDNEY--LHY 282


                 ....
gi 154519778  80 QDDW 83
Cdd:PLN02372 283 QDDW 286
 
Name Accession Description Interval E-value
PLN02372 PLN02372
violaxanthin de-epoxidase
 1-83 7.86e-16

violaxanthin de-epoxidase


Pssm-ID: 215212 [Multi-domain]  Cd Length: 455  Bit Score: 70.26  E-value: 7.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154519778   1 DFSGKWFITSGLNPTFDTFNCQRP*F*TE-SD**VGYW*RRILIPVG*LLSSG*L**H*LEIRTASLGYSY*GD*gdLHY 79
Cdd:PLN02372 205 DFNGRWYITSGLNKTFDTFDCQLHEFTAEdPDKLVGNLNWRINTPDGGFFTRSAVQRFVQDPNQPGILYNHDNEY--LHY 282


                 ....
gi 154519778  80 QDDW 83
Cdd:PLN02372 283 QDDW 286
lipocalin_VDE cd19420
lipocalin domain of violaxanthin deepoxidase and similar proteins; Plant violaxanthin ...
 1-83 1.56e-14

lipocalin domain of violaxanthin deepoxidase and similar proteins; Plant violaxanthin de-epoxidase (VDE, EC 1.23.5.1) participates in the xanthophyll cycle for controlling the concentration of zeaxanthin in chloroplasts. It catalyzes the conversion of violaxanthin to antheraxanthin and zeaxanthin in strong light, and plays a central role in adjusting photosynthetic activity to changing light conditions. In addition, maize VDE has been shown to interact with sugarcane mosaic virus helper component-proteinase, HC-(SCMV), and to attenuate the RNA silencing suppression activity of the latter. VDE belongs to the lipocalin/cytosolic fatty-acid binding protein family which have a large beta-barrel ligand-binding cavity. Lipocalins are mainly low molecular weight extracellular proteins that bind principally small hydrophobic ligands, and form covalent or non-covalent complexes with soluble macromolecules, as well as membrane bound-receptors. They participate in processes such as ligand transport, modulation of cell growth and metabolism, regulation of immune response, smell reception, tissue development and animal behavior. Cytosolic fatty-acid binding proteins, also bind hydrophobic ligands in a non-covalent, reversible manner, and have been implicated in intracellular uptake, transport and storage of hydrophobic ligands, regulation of lipid metabolism and sequestration of excess toxic fatty acids, as well as in signaling, gene expression, inflammation, cell growth and proliferation, and cancer development.


Pssm-ID: 381195  Cd Length: 177  Bit Score: 64.48  E-value: 1.56e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154519778   1 DFSGKWFITSGLNPTFDTFNCQRP*F*TE-SD**VGYW*RRILIPVG*LLSSG*L**H*LEIRTASLGYSY*gD*GDLHY 79
Cdd:cd19420   21 DFNGKWYITAGLNPTFDTFDCQLHFFHVEgDDKLVGKINWRIKTPDGGFFTRSAVQRFVQDPNQPGILYNH--DNEYLHY 98


                 ....
gi 154519778  80 QDDW 83
Cdd:cd19420   99 QDDW 102
VDE pfam07137
VDE lipocalin domain; This family represents a conserved region approximately 150 residues ...
 1-83 3.35e-12

VDE lipocalin domain; This family represents a conserved region approximately 150 residues long within plant violaxanthin de-epoxidase (VDE). In higher plants, violaxanthin de-epoxidase forms part of a conserved system that dissipates excess energy as heat in the light-harvesting complexes of photosystem II (PSII), thus protecting them from photo-inhibitory damage.


Pssm-ID: 462099 [Multi-domain]  Cd Length: 240  Bit Score: 59.26  E-value: 3.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154519778    1 DFSGKWFITSGLNPTFDTFNCQRP*F*TESD**vGYW*RRI--LIPVG*llSSG*L**H*LE---IRTASLGYSY*GD*G 75
Cdd:pfam07137  93 SFEGRWYIVAGLNPAFDCFDCQRHTFSAPEP---GKLVGKLnwRVPRP---DGGFFTRSLVQtfvQDPHTPGILFNHDNE 166


                  ....*...
gi 154519778   76 DLHYQDDW 83
Cdd:pfam07137 167 YLHYQDDW 174
 
Name Accession Description Interval E-value
PLN02372 PLN02372
violaxanthin de-epoxidase
 1-83 7.86e-16

violaxanthin de-epoxidase


Pssm-ID: 215212 [Multi-domain]  Cd Length: 455  Bit Score: 70.26  E-value: 7.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154519778   1 DFSGKWFITSGLNPTFDTFNCQRP*F*TE-SD**VGYW*RRILIPVG*LLSSG*L**H*LEIRTASLGYSY*GD*gdLHY 79
Cdd:PLN02372 205 DFNGRWYITSGLNKTFDTFDCQLHEFTAEdPDKLVGNLNWRINTPDGGFFTRSAVQRFVQDPNQPGILYNHDNEY--LHY 282


                 ....
gi 154519778  80 QDDW 83
Cdd:PLN02372 283 QDDW 286
lipocalin_VDE cd19420
lipocalin domain of violaxanthin deepoxidase and similar proteins; Plant violaxanthin ...
 1-83 1.56e-14

lipocalin domain of violaxanthin deepoxidase and similar proteins; Plant violaxanthin de-epoxidase (VDE, EC 1.23.5.1) participates in the xanthophyll cycle for controlling the concentration of zeaxanthin in chloroplasts. It catalyzes the conversion of violaxanthin to antheraxanthin and zeaxanthin in strong light, and plays a central role in adjusting photosynthetic activity to changing light conditions. In addition, maize VDE has been shown to interact with sugarcane mosaic virus helper component-proteinase, HC-(SCMV), and to attenuate the RNA silencing suppression activity of the latter. VDE belongs to the lipocalin/cytosolic fatty-acid binding protein family which have a large beta-barrel ligand-binding cavity. Lipocalins are mainly low molecular weight extracellular proteins that bind principally small hydrophobic ligands, and form covalent or non-covalent complexes with soluble macromolecules, as well as membrane bound-receptors. They participate in processes such as ligand transport, modulation of cell growth and metabolism, regulation of immune response, smell reception, tissue development and animal behavior. Cytosolic fatty-acid binding proteins, also bind hydrophobic ligands in a non-covalent, reversible manner, and have been implicated in intracellular uptake, transport and storage of hydrophobic ligands, regulation of lipid metabolism and sequestration of excess toxic fatty acids, as well as in signaling, gene expression, inflammation, cell growth and proliferation, and cancer development.


Pssm-ID: 381195  Cd Length: 177  Bit Score: 64.48  E-value: 1.56e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154519778   1 DFSGKWFITSGLNPTFDTFNCQRP*F*TE-SD**VGYW*RRILIPVG*LLSSG*L**H*LEIRTASLGYSY*gD*GDLHY 79
Cdd:cd19420   21 DFNGKWYITAGLNPTFDTFDCQLHFFHVEgDDKLVGKINWRIKTPDGGFFTRSAVQRFVQDPNQPGILYNH--DNEYLHY 98


                 ....
gi 154519778  80 QDDW 83
Cdd:cd19420   99 QDDW 102
VDE pfam07137
VDE lipocalin domain; This family represents a conserved region approximately 150 residues ...
 1-83 3.35e-12

VDE lipocalin domain; This family represents a conserved region approximately 150 residues long within plant violaxanthin de-epoxidase (VDE). In higher plants, violaxanthin de-epoxidase forms part of a conserved system that dissipates excess energy as heat in the light-harvesting complexes of photosystem II (PSII), thus protecting them from photo-inhibitory damage.


Pssm-ID: 462099 [Multi-domain]  Cd Length: 240  Bit Score: 59.26  E-value: 3.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 154519778    1 DFSGKWFITSGLNPTFDTFNCQRP*F*TESD**vGYW*RRI--LIPVG*llSSG*L**H*LE---IRTASLGYSY*GD*G 75
Cdd:pfam07137  93 SFEGRWYIVAGLNPAFDCFDCQRHTFSAPEP---GKLVGKLnwRVPRP---DGGFFTRSLVQtfvQDPHTPGILFNHDNE 166


                  ....*...
gi 154519778   76 DLHYQDDW 83
Cdd:pfam07137 167 YLHYQDDW 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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