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Conserved domains on  [gi|124389587|gb|ABN10977|]
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nitrogenase iron protein, partial [Thioalkalispira microaerophila]

Protein Classification

P-loop NTPase family protein( domain architecture ID 1562424)

P-loop NTPase (nucleoside triphosphate hydrolase) family protein contains two conserved sequence signatures, the Walker A motif (the P-loop proper) and Walker B motif which bind, respectively, the beta and gamma phosphate moieties of the bound nucleotide (typically ATP or GTP), and a Mg(2+) cation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NifH/CfbC super family cl43394
Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport ...
 1-127 2.80e-88

Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport and metabolism, Inorganic ion transport and metabolism];


The actual alignment was detected with superfamily member COG1348:

Pssm-ID: 440959  Cd Length: 276  Bit Score: 257.41  E-value: 2.80e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGsvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:COG1348   21 NLSAALAEMGKKVMQIGCDPKADSTRLLLGGKRIPTVLDTLREKG--EDVELEDIVFEGFGGVKCVEAGGPEPGVGCAGR 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:COG1348   99 GIITAIELLEELGAYEEDLDVVIYDVLGDVVCGGFAMPIREGYADEI 145
 
Name Accession Description Interval E-value
NifH/CfbC COG1348
Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport ...
 1-127 2.80e-88

Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440959  Cd Length: 276  Bit Score: 257.41  E-value: 2.80e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGsvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:COG1348   21 NLSAALAEMGKKVMQIGCDPKADSTRLLLGGKRIPTVLDTLREKG--EDVELEDIVFEGFGGVKCVEAGGPEPGVGCAGR 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:COG1348   99 GIITAIELLEELGAYEEDLDVVIYDVLGDVVCGGFAMPIREGYADEI 145
nifH TIGR01287
nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also ...
 1-127 2.08e-82

nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also called nitrogenase reductase or nitrogenase component II. This model includes molybdenum-iron nitrogenase reductase (nifH), vanadium-iron nitrogenase reductase (vnfH), and iron-iron nitrogenase reductase (anfH). The model excludes the homologous protein from the light-independent protochlorophyllide reductase. [Central intermediary metabolism, Nitrogen fixation]


Pssm-ID: 273538  Cd Length: 275  Bit Score: 242.68  E-value: 2.08e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587    1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:TIGR01287  19 NIAAALAEMGKKVMIVGCDPKADSTRLLLGGKAQPTVLDVLREKGA-EDLELEDVIKEGFGGIRCVESGGPEPGVGCAGR 97

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 124389587   81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:TIGR01287  98 GVITAINLLEELGAYEDDLDFVFYDVLGDVVCGGFAMPIREGKAQEI 144
NifH cd02040
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ...
 1-127 6.53e-80

nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia.


Pssm-ID: 349759  Cd Length: 265  Bit Score: 235.87  E-value: 6.53e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGsvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:cd02040   19 NLSAALAEMGKKVLHVGCDPKADSTRLLLGGKAIPTVLDTLREKG--EVEELEDVIKEGFNGIKCVESGGPEPGVGCAGR 96

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:cd02040   97 GIITAINLLEELGAYEEDLDVVFYDVLGDVVCGGFAMPIREGYADEV 143
Fer4_NifH pfam00142
4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;
1-127 1.39e-71

4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;


Pssm-ID: 395090  Cd Length: 271  Bit Score: 215.00  E-value: 1.39e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587    1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSVEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:pfam00142  19 NLSAALAEMGKKVLVVGCDPKADSTRLLLGGKLQPTVLDTAREKGYVEDVEVEDVVYKGYGGVKCVESGGPEPGVGCAGR 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 124389587   81 GVITAINFLEEEGAYDeDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:pfam00142  99 GVITAINLLEELGAYD-DLDFVLYDVLGDVVCGGFAMPIREGKAQEI 144
F430_CfbC NF033200
Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, ...
 1-127 4.69e-64

Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, very closely related to the nitrogenase iron protein, was identified as a subunit involved in biosynthesis of coenzyme F430 in archaeal methanogens and archaeal anaerobic methanotrophs.


Pssm-ID: 380202  Cd Length: 260  Bit Score: 195.48  E-value: 4.69e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGsveDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:NF033200  19 NLAAALSEEGKKVMVIGCDPKADSTRTLMGGRRIPTILDLLRENK---NIKEEDVVFEGYGGVRCVESGGPEPGVGCAGR 95

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:NF033200  96 GIIVAMQLLEKLGAFMEDLDVIIYDVLGDVVCGGFAVPLREGYADEV 142
nifH PRK13233
nitrogenase iron protein;
1-127 1.07e-62

nitrogenase iron protein;


Pssm-ID: 183905  Cd Length: 275  Bit Score: 192.34  E-value: 1.07e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAE-AGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAG 79
Cdd:PRK13233  21 NTAAAMAYfHDKKVFIHGCDPKADSTRLILGGKPQTTMMDTLRELGE-EKVTPDKVIKTGFKDIRCVESGGPEPGVGCAG 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 124389587  80 RGVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:PRK13233 100 RGVITAIDLMEENGAYTDDLDFVFFDVLGDVVCGGFAMPIRDGKAQEV 147
 
Name Accession Description Interval E-value
NifH/CfbC COG1348
Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport ...
 1-127 2.80e-88

Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440959  Cd Length: 276  Bit Score: 257.41  E-value: 2.80e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGsvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:COG1348   21 NLSAALAEMGKKVMQIGCDPKADSTRLLLGGKRIPTVLDTLREKG--EDVELEDIVFEGFGGVKCVEAGGPEPGVGCAGR 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:COG1348   99 GIITAIELLEELGAYEEDLDVVIYDVLGDVVCGGFAMPIREGYADEI 145
nifH TIGR01287
nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also ...
 1-127 2.08e-82

nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also called nitrogenase reductase or nitrogenase component II. This model includes molybdenum-iron nitrogenase reductase (nifH), vanadium-iron nitrogenase reductase (vnfH), and iron-iron nitrogenase reductase (anfH). The model excludes the homologous protein from the light-independent protochlorophyllide reductase. [Central intermediary metabolism, Nitrogen fixation]


Pssm-ID: 273538  Cd Length: 275  Bit Score: 242.68  E-value: 2.08e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587    1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:TIGR01287  19 NIAAALAEMGKKVMIVGCDPKADSTRLLLGGKAQPTVLDVLREKGA-EDLELEDVIKEGFGGIRCVESGGPEPGVGCAGR 97

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 124389587   81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:TIGR01287  98 GVITAINLLEELGAYEDDLDFVFYDVLGDVVCGGFAMPIREGKAQEI 144
NifH cd02040
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ...
 1-127 6.53e-80

nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia.


Pssm-ID: 349759  Cd Length: 265  Bit Score: 235.87  E-value: 6.53e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGsvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:cd02040   19 NLSAALAEMGKKVLHVGCDPKADSTRLLLGGKAIPTVLDTLREKG--EVEELEDVIKEGFNGIKCVESGGPEPGVGCAGR 96

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:cd02040   97 GIITAINLLEELGAYEEDLDVVFYDVLGDVVCGGFAMPIREGYADEV 143
Fer4_NifH pfam00142
4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;
1-127 1.39e-71

4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;


Pssm-ID: 395090  Cd Length: 271  Bit Score: 215.00  E-value: 1.39e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587    1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSVEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:pfam00142  19 NLSAALAEMGKKVLVVGCDPKADSTRLLLGGKLQPTVLDTAREKGYVEDVEVEDVVYKGYGGVKCVESGGPEPGVGCAGR 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 124389587   81 GVITAINFLEEEGAYDeDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:pfam00142  99 GVITAINLLEELGAYD-DLDFVLYDVLGDVVCGGFAMPIREGKAQEI 144
F430_CfbC NF033200
Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, ...
 1-127 4.69e-64

Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, very closely related to the nitrogenase iron protein, was identified as a subunit involved in biosynthesis of coenzyme F430 in archaeal methanogens and archaeal anaerobic methanotrophs.


Pssm-ID: 380202  Cd Length: 260  Bit Score: 195.48  E-value: 4.69e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGsveDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:NF033200  19 NLAAALSEEGKKVMVIGCDPKADSTRTLMGGRRIPTILDLLRENK---NIKEEDVVFEGYGGVRCVESGGPEPGVGCAGR 95

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:NF033200  96 GIIVAMQLLEKLGAFMEDLDVIIYDVLGDVVCGGFAVPLREGYADEV 142
nifH PRK13233
nitrogenase iron protein;
1-127 1.07e-62

nitrogenase iron protein;


Pssm-ID: 183905  Cd Length: 275  Bit Score: 192.34  E-value: 1.07e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAE-AGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAG 79
Cdd:PRK13233  21 NTAAAMAYfHDKKVFIHGCDPKADSTRLILGGKPQTTMMDTLRELGE-EKVTPDKVIKTGFKDIRCVESGGPEPGVGCAG 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 124389587  80 RGVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:PRK13233 100 RGVITAIDLMEENGAYTDDLDFVFFDVLGDVVCGGFAMPIRDGKAQEV 147
NifH-like cd02117
NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) ...
 1-127 2.26e-61

NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) of the protochlorophyllide reductase, and the BchX subunit of the Chlorophyllide reductase. Members of this family use energy from ATP hydrolysis and transfer electrons through a Fe4-S4 cluster to other subunit for substrate reduction


Pssm-ID: 349761  Cd Length: 266  Bit Score: 188.73  E-value: 2.26e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSVEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:cd02117   19 NLSAALAEGGKKVLHVGCDPKHDSTLLLTGGKVPPTIDEMLTEDGTAEELRREDLLFSGFNGVDCVEAGGPEPGVGCGGR 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:cd02117   99 GIGTMLELLEEHGLLDDDYDVVIFDVLGDVVCGGFAAPLRRGFAQKV 145
PRK13230 PRK13230
nitrogenase reductase-like protein; Reviewed
 1-127 4.49e-49

nitrogenase reductase-like protein; Reviewed


Pssm-ID: 183903  Cd Length: 279  Bit Score: 157.63  E-value: 4.49e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAqTTVMHLAAEAGsVEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:PRK13230  20 NIAAALAESGKKVLVVGCDPKADCTRNLVGEKI-PTVLDVLREKG-IDNLGLEDIIYEGFNGIYCVESGGPEPGYGCAGR 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 124389587  81 GVITAINFLEEEGAYDE-DLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:PRK13230  98 GVITAIDLLKKLGVFEElGPDVVIYDILGDVVCGGFAMPLQKGLADDV 145
PRK13231 PRK13231
nitrogenase reductase-like protein; Reviewed
 1-127 1.31e-42

nitrogenase reductase-like protein; Reviewed


Pssm-ID: 183904  Cd Length: 264  Bit Score: 140.70  E-value: 1.31e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEaGKKVMIVGCDPKADSTRlILHSKAQTTVMHLAAEAgsvEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:PRK13231  21 NMAAAYSN-DHRVLVIGCDPKADTTR-TLCGKRIPTVLDTLKDN---RKPELEDIIHEGFNGILCVESGGPEPGVGCAGR 95

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 124389587  81 GVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:PRK13231  96 GVIVAMNLLENLGVFDEDIDVVIYDVLGDVVCGGFSVPLREDYADEV 142
Bchl-like cd02032
L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. ...
 1-119 2.74e-34

L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. Protochlorophyllide reductase catalyzes the reductive formation of chlorophyllide from protochlorophyllide during biosynthesis of chlorophylls and bacteriochlorophylls. Three genes, bchL, bchN and bchB, are involved in light-independent protochlorophyllide reduction in bacteriochlorophyll biosynthesis. In cyanobacteria, algae, and gymnosperms, three similar genes, chlL, chlN and chlB are involved in protochlorophyllide reduction during chlorophylls biosynthesis. BchL/chlL, bchN/chlN and bchB/chlB exhibit significant sequence similarity to the nifH, nifD and nifK subunits of nitrogenase, respectively. Nitrogenase catalyzes the reductive formation of ammonia from dinitrogen.


Pssm-ID: 349752  Cd Length: 267  Bit Score: 119.32  E-value: 2.74e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSVEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:cd02032   19 NLSAAFAKRGKKVLQIGCDPKHDSTFTLTGFLIPTVIDVLQSVDFHYEEVWPEDVIFTGYGGVDCVEAGGPPAGTGCGGY 98

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 124389587  81 GVITAINFLEEEGAYDeDLDFVFYDVLGVVVCGGFAMPI 119
Cdd:cd02032   99 VVGETVKLLKELNAFD-EYDVILFDVLGDVVCGGFAAPL 136
chlL PRK13185
protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional
 1-119 3.41e-31

protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional


Pssm-ID: 237293  Cd Length: 270  Bit Score: 111.59  E-value: 3.41e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSVEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:PRK13185  21 NLSAAFAKLGKKVLQIGCDPKHDSTFTLTGKLVPTVIDILEEVDFHSEELRPEDFVYEGYNGVDCVEAGGPPAGTGCGGY 100

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 124389587  81 GVITAINFLEEEGAYDeDLDFVFYDVLGVVVCGGFAMPI 119
Cdd:PRK13185 101 VVGETVKLLKEHHLLD-DYDVILFDVLGDVVCGGFAAPL 138
BchX cd02033
X-subunit of protochlorophyllide reductase; Chlorophyllide reductase converts chlorophylls ...
 1-127 1.56e-28

X-subunit of protochlorophyllide reductase; Chlorophyllide reductase converts chlorophylls into bacteriochlorophylls by reducing the chlorin B-ring. This family contains the X subunit of this three-subunit enzyme. Sequence and structure similarity between bchX, protochlorophyllide reductase L subunit (bchL and chlL) and nitrogenase Fe protein (nifH gene) suggest their functional similarity. Members of the BchX family serve as the unique electron donors to their respective catalytic subunits (bchN-bchB, bchY-bchZ and nitrogenase component 1). Mechanistically, they hydrolyze ATP and transfer electrons through a Fe4-S4 cluster.


Pssm-ID: 349753  Cd Length: 329  Bit Score: 105.68  E-value: 1.56e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAE---AGsvEDLELEDVlCVGYGDVKCVESGGPEPGVGC 77
Cdd:cd02033   50 NLSYMMAQQGKRVLLIGCDPKSDTTSLLFGGKACPTIIETSTRkklAG--EEVKIGDV-CFKRGGVFAMELGGPEVGRGC 126

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 124389587  78 AGRGVITAINFLEEEGAYDEDLDFVFYDVLGVVVCGGFAMPIRENKAQEI 127
Cdd:cd02033  127 GGRGIIHGFELLEKLGFHDWGFDYVLLDFLGDVVCGGFGLPIARDMCQKV 176
chlL CHL00072
photochlorophyllide reductase subunit L
 1-119 3.29e-28

photochlorophyllide reductase subunit L


Pssm-ID: 177011  Cd Length: 290  Bit Score: 104.05  E-value: 3.29e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLILHSKAQTTVMHLAAEAGSVEDLELEDVLCVGYGDVKCVESGGPEPGVGCAGR 80
Cdd:CHL00072  19 NISIALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQSKDYHYEDVWPEDVIYKGYGGVDCVEAGGPPAGAGCGGY 98

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 124389587  81 GVITAINFLEEEGAYDEdLDFVFYDVLGVVVCGGFAMPI 119
Cdd:CHL00072  99 VVGETVKLLKELNAFYE-YDIILFDVLGDVVCGGFAAPL 136
AAA_31 pfam13614
AAA domain; This family includes a wide variety of AAA domains including some that have lost ...
 1-56 1.24e-05

AAA domain; This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.


Pssm-ID: 433350 [Multi-domain]  Cd Length: 177  Bit Score: 42.19  E-value: 1.24e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 124389587    1 NLVAALAEAGKKVMIVGCDPKADSTR--LILHSKAQTTVMHLAAEAGSVEDLELEDVL 56
Cdd:pfam13614  21 NLAAALAKKGKKVLLIDLDPQGNATSglGIDKNNVEKTIYELLIGECNIEEAIIKTVI 78
ParA COG1192
ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein ...
 1-50 1.19e-03

ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440805 [Multi-domain]  Cd Length: 253  Bit Score: 37.15  E-value: 1.19e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRL--ILHSKAQTTVMHLAAEAGSVEDL 50
Cdd:COG1192   21 NLAAALARRGKRVLLIDLDPQGNLTSGlgLDPDDLDPTLYDLLLDDAPLEDA 72
ParAB_family cd02042
partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved ...
 1-28 1.35e-03

partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.


Pssm-ID: 349760 [Multi-domain]  Cd Length: 130  Bit Score: 35.98  E-value: 1.35e-03
                         10        20
                 ....*....|....*....|....*...
gi 124389587   1 NLVAALAEAGKKVMIVGCDPKADSTRLI 28
Cdd:cd02042   20 NLAAALALRGKRVLLIDLDPQGSLTSWL 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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