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Conserved domains on  [gi|51451771|gb|AAU03327|]
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maturase, partial (mitochondrion) [Micrantheum hexandrum]

Protein Classification

reverse transcriptase/maturase family protein( domain architecture ID 10108727)

reverse transcriptase/maturase family protein similar to reverse transcriptases with group II intron origin that transcribe DNA using RNA as template

EC:  2.7.7.49
Gene Ontology:  GO:0006278|GO:0003723|GO:0003964
PubMed:  8828137

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RT_G2_intron cd01651
RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA ...
 1-136 5.74e-31

RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with both gag-like and pol-like genes. This subfamily of proteins appears to have captured the RT sequences from transposable elements, which lack long terminal repeats (LTRs).


:

Pssm-ID: 238828 [Multi-domain]  Cd Length: 226  Bit Score: 120.38  E-value: 5.74e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771   1 MVLESIYDPEFPDTSH-FRSGRGCHSVLRRIKE-EWGTSRWFLEFDIRNCFHTIDRHRLISIFKEEIDDPKFFDSIQKVF 78
Cdd:cd01651  31 LVLEPIYEPRFSDCSYgFRPGRSAHDALKAIRRnVKGGYTWVIEGDIKGFFDNIDHDLLLKILKRRIGDKRVLRLIRKWL 110

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771  79 SAGRLVGGEKGPDS--VPHSVLLSALPGNIYLHKLDQEIGRIRQKYEIPIVQRIRSVLLR 136
Cdd:cd01651 111 KAGVLEDGKLVETEkgTPQGGVISPLLANIYLHELDKFVEEKLKEYYDTSDPKFRRLRYV 170
 
Name Accession Description Interval E-value
RT_G2_intron cd01651
RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA ...
 1-136 5.74e-31

RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with both gag-like and pol-like genes. This subfamily of proteins appears to have captured the RT sequences from transposable elements, which lack long terminal repeats (LTRs).


Pssm-ID: 238828 [Multi-domain]  Cd Length: 226  Bit Score: 120.38  E-value: 5.74e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771   1 MVLESIYDPEFPDTSH-FRSGRGCHSVLRRIKE-EWGTSRWFLEFDIRNCFHTIDRHRLISIFKEEIDDPKFFDSIQKVF 78
Cdd:cd01651  31 LVLEPIYEPRFSDCSYgFRPGRSAHDALKAIRRnVKGGYTWVIEGDIKGFFDNIDHDLLLKILKRRIGDKRVLRLIRKWL 110

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771  79 SAGRLVGGEKGPDS--VPHSVLLSALPGNIYLHKLDQEIGRIRQKYEIPIVQRIRSVLLR 136
Cdd:cd01651 111 KAGVLEDGKLVETEkgTPQGGVISPLLANIYLHELDKFVEEKLKEYYDTSDPKFRRLRYV 170
RVT_1 pfam00078
Reverse transcriptase (RNA-dependent DNA polymerase); A reverse transcriptase gene is usually ...
 15-128 3.30e-03

Reverse transcriptase (RNA-dependent DNA polymerase); A reverse transcriptase gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. Reverse transcriptases occur in a variety of mobile elements, including retrotransposons, retroviruses, group II introns, bacterial msDNAs, hepadnaviruses, and caulimoviruses.


Pssm-ID: 395031 [Multi-domain]  Cd Length: 189  Bit Score: 38.82  E-value: 3.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771    15 SHFRSGRGCHsvlrrikeewGTSRWFLEFDIRNCFHTIDRHRLISIFKEEIDDPKFFDSIQKvFSAGRLVggEKGpdsVP 94
Cdd:pfam00078  41 PGFRPGLAKL----------KKAKWFLKLDLKKAFDQVPLDELDRKLTAFTTPPININWNGE-LSGGRYE--WKG---LP 104

                          90       100       110
                  ....*....|....*....|....*....|....
gi 51451771    95 HSVLLSALPGNIYLHKLDQEigrIRQKYEIPIVQ 128
Cdd:pfam00078 105 QGLVLSPALFQLFMNELLRP---LRKRAGLTLVR 135
 
Name Accession Description Interval E-value
RT_G2_intron cd01651
RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA ...
 1-136 5.74e-31

RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with both gag-like and pol-like genes. This subfamily of proteins appears to have captured the RT sequences from transposable elements, which lack long terminal repeats (LTRs).


Pssm-ID: 238828 [Multi-domain]  Cd Length: 226  Bit Score: 120.38  E-value: 5.74e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771   1 MVLESIYDPEFPDTSH-FRSGRGCHSVLRRIKE-EWGTSRWFLEFDIRNCFHTIDRHRLISIFKEEIDDPKFFDSIQKVF 78
Cdd:cd01651  31 LVLEPIYEPRFSDCSYgFRPGRSAHDALKAIRRnVKGGYTWVIEGDIKGFFDNIDHDLLLKILKRRIGDKRVLRLIRKWL 110

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771  79 SAGRLVGGEKGPDS--VPHSVLLSALPGNIYLHKLDQEIGRIRQKYEIPIVQRIRSVLLR 136
Cdd:cd01651 111 KAGVLEDGKLVETEkgTPQGGVISPLLANIYLHELDKFVEEKLKEYYDTSDPKFRRLRYV 170
RT_Bac_retron_I cd01646
RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The ...
 44-124 1.88e-05

RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.


Pssm-ID: 238824 [Multi-domain]  Cd Length: 158  Bit Score: 45.01  E-value: 1.88e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771  44 DIRNCFHTIDRHRLISIFKEEIDDPK-------FFDSIQKvFSAGRLVGGEKGpdsVPHSVLLSALPGNIYLHKLDQEIG 116
Cdd:cd01646   2 DISNFYDSIYTHSLPWALHGKIKAKQllkllrlLGNLLDL-LLLSSQYGQTNG---LPIGPLTSRFLANIYLNDVDHELK 77


                ....*...
gi 51451771 117 RIRQKYEI 124
Cdd:cd01646  78 SKLKGVDY 85
RVT_1 pfam00078
Reverse transcriptase (RNA-dependent DNA polymerase); A reverse transcriptase gene is usually ...
 15-128 3.30e-03

Reverse transcriptase (RNA-dependent DNA polymerase); A reverse transcriptase gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. Reverse transcriptases occur in a variety of mobile elements, including retrotransposons, retroviruses, group II introns, bacterial msDNAs, hepadnaviruses, and caulimoviruses.


Pssm-ID: 395031 [Multi-domain]  Cd Length: 189  Bit Score: 38.82  E-value: 3.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51451771    15 SHFRSGRGCHsvlrrikeewGTSRWFLEFDIRNCFHTIDRHRLISIFKEEIDDPKFFDSIQKvFSAGRLVggEKGpdsVP 94
Cdd:pfam00078  41 PGFRPGLAKL----------KKAKWFLKLDLKKAFDQVPLDELDRKLTAFTTPPININWNGE-LSGGRYE--WKG---LP 104

                          90       100       110
                  ....*....|....*....|....*....|....
gi 51451771    95 HSVLLSALPGNIYLHKLDQEigrIRQKYEIPIVQ 128
Cdd:pfam00078 105 QGLVLSPALFQLFMNELLRP---LRKRAGLTLVR 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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