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Conserved domains on  [gi|21113345|gb|AAM41490|]
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conserved hypothetical protein [Xanthomonas campestris pv. campestris str. ATCC 33913]

Protein Classification

BolA family protein( domain architecture ID 10000955)

BolA family protein may be a stress-responsive transcriptional regulator and may also participate in iron metabolism; similar to mammalian BolA-like proteins that act as iron-sulfur (Fe-S) cluster assembly factors that facilitate [2Fe-2S] cluster insertion into a subset of cytosolic proteins, and to Haemophilus influenzae DNA-binding transcriptional regulator BolA

CATH:  3.30.300.90

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 1-88 1.71e-42

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


:

Pssm-ID: 440041  Cd Length: 90  Bit Score: 133.39  E-value: 1.71e-42
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21113345  1 MSRVDRIRAALQAALAPVELEVVDDSHRHAGHAGArDGRGHFNVRVVSSVFAGKAPLARHRAVYAAVGEMMQTDIHALSI 80
Cdd:COG0271  1 MSRQERIEEKLTAALAPEHLEVIDESHLHAGHAGA-GGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAI 79


               ....*...
gi 21113345 81 EALAPGEA 88
Cdd:COG0271 80 HAYTPEEW 87
 
Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 1-88 1.71e-42

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 133.39  E-value: 1.71e-42
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21113345  1 MSRVDRIRAALQAALAPVELEVVDDSHRHAGHAGArDGRGHFNVRVVSSVFAGKAPLARHRAVYAAVGEMMQTDIHALSI 80
Cdd:COG0271  1 MSRQERIEEKLTAALAPEHLEVIDESHLHAGHAGA-GGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAI 79


               ....*...
gi 21113345 81 EALAPGEA 88
Cdd:COG0271 80 HAYTPEEW 87
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 11-87 1.66e-33

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 110.24  E-value: 1.66e-33
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21113345   11 LQAALAPVELEVVDDSHRHAGHAGArdGRGHFNVRVVSSVFAGKAPLARHRAVYAAVGEMMQTDIHALSIEALAPGE 87
Cdd:pfam01722  1 LTEALAPTHLEVEDESHKHAGHAGG--GETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKTYTPEE 75
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 5-87 2.29e-15

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 65.19  E-value: 2.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21113345    5 DRIRAALQAALAPVELEVVDDSHRHAGHAGARDgrgHFNVRVVSSVFAGKAPLARHRAVYAAVGEMMQTDIHALSIEALA 84
Cdd:PRK11628   5 EQIEEKLRAAFQPVFLEVVDESYRHNVPAGSES---HFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYT 81


                 ...
gi 21113345   85 PGE 87
Cdd:PRK11628  82 IKE 84
 
Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 1-88 1.71e-42

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 133.39  E-value: 1.71e-42
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21113345  1 MSRVDRIRAALQAALAPVELEVVDDSHRHAGHAGArDGRGHFNVRVVSSVFAGKAPLARHRAVYAAVGEMMQTDIHALSI 80
Cdd:COG0271  1 MSRQERIEEKLTAALAPEHLEVIDESHLHAGHAGA-GGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAI 79


               ....*...
gi 21113345 81 EALAPGEA 88
Cdd:COG0271 80 HAYTPEEW 87
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 11-87 1.66e-33

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 110.24  E-value: 1.66e-33
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21113345   11 LQAALAPVELEVVDDSHRHAGHAGArdGRGHFNVRVVSSVFAGKAPLARHRAVYAAVGEMMQTDIHALSIEALAPGE 87
Cdd:pfam01722  1 LTEALAPTHLEVEDESHKHAGHAGG--GETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKTYTPEE 75
IbaG COG5007
Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];
7-87 1.19e-18

Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];


Pssm-ID: 444031  Cd Length: 81  Bit Score: 72.49  E-value: 1.19e-18
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21113345  7 IRAALQAALAPVELEVVDDSHrhaghagardgrgHFNVRVVSSVFAGKAPLARHRAVYAAVGEMMQTD-IHALSIEALAP 85
Cdd:COG5007  6 IKQLIEAGLPCAEVEVEGDGS-------------HFEAIVVSDAFEGLSRVKRQQLVYAPLGDYIASGeIHALSIKTYTP 72


               ..
gi 21113345 86 GE 87
Cdd:COG5007 73 EE 74
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 5-87 2.29e-15

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 65.19  E-value: 2.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21113345    5 DRIRAALQAALAPVELEVVDDSHRHAGHAGARDgrgHFNVRVVSSVFAGKAPLARHRAVYAAVGEMMQTDIHALSIEALA 84
Cdd:PRK11628   5 EQIEEKLRAAFQPVFLEVVDESYRHNVPAGSES---HFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYT 81


                 ...
gi 21113345   85 PGE 87
Cdd:PRK11628  82 IKE 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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