NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|28175702|gb|AAH45147|]
View 

Myocyte enhancer factor 2B [Mus musculus]

Protein Classification

MEF2 family transcription factor( domain architecture ID 13416711)

MEF2 family transcription factor is a MADS (MCM1, Agamous, Deficiens, and SRF)-box transcription factor, similar to human myocyte-specific enhancer factor 2C, a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 2-78 3.12e-37

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


:

Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 128.05  E-value: 3.12e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28175702   2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHES 78
Cdd:cd00265   1 GRGKIEIKRIENSTNRQVTFSKRRNGLLKKAHELSVLCDAEVALIIFSSSGKLYEFSSPSMEKIIERYQKTSGSSLW 77
ARG80 super family cl34888
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 1-215 4.86e-09

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


The actual alignment was detected with superfamily member COG5068:

Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 57.33  E-value: 4.86e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVL------LKYTEYSE 74
Cdd:COG5068  81 VTGRKIGISYITNKTKRSVTFSKRKHGINKKAFELSVLTGTEVLLLVISENGLVHTFTTPKLESVVkslegkSLIQSPCS 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702  75 PHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPPPRiYPVAPAMSVSELSYRVPPATPgcd 154
Cdd:COG5068 161 NAPSDSSEEPSSSASFSVDPNDNNPMGSFQHNGSPQTNFIPLQNPQTQQYQQHSS-RKDHPTVPHSNTNNGRPPAKF--- 236

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28175702 155 pgglgEAPSVHSRPPHFR-PPGLGHPIFSPSHLASKTPPPLYLATDGRRPDLPPGLRSLYSG 215
Cdd:COG5068 237 -----MIPELHSSHSTLDlPSDFISDSGFPNQSSTSIFPLDSAIIQITPPHLPNNPPQENRH 293
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 117-338 1.51e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   117 LGGDRGSASPPPRIYPVAPAMSVSELSYRVPpatpgcdpgGLGEAPSVHSRPPHFRPPGLGHPIFSPSHLASKTPPPlyl 196
Cdd:PHA03247 2638 PDPHPPPTVPPPERPRDDPAPGRVSRPRRAR---------RLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPP--- 2705

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   197 atdgRRPDLPPglRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPPTRDAVDPARPVARSLCKEGP 276
Cdd:PHA03247 2706 ----PTPEPAP--HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP 2779

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28175702   277 PSRGASPPTPPVSIKSERLsPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHRLTPDSWP 338
Cdd:PHA03247 2780 PRRLTRPAVASLSESRESL-PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840
 
Name Accession Description Interval E-value
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 2-78 3.12e-37

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 128.05  E-value: 3.12e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28175702   2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHES 78
Cdd:cd00265   1 GRGKIEIKRIENSTNRQVTFSKRRNGLLKKAHELSVLCDAEVALIIFSSSGKLYEFSSPSMEKIIERYQKTSGSSLW 77
MADS smart00432
MADS domain;
2-60 2.87e-30

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 109.57  E-value: 2.87e-30
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 28175702      2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASS 60
Cdd:smart00432   1 GRRKIEIKRIENKTNRQVTFSKRRNGLFKKAHELSVLCDAEVALIVFSPTGKLYEFASP 59
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
10-57 3.22e-23

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 90.56  E-value: 3.22e-23
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 28175702    10 RILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQY 57
Cdd:pfam00319   1 RIENKRARQVTFSKRRKGLFKKASELSVLCGAEVAVIVFSPTGKLYTF 48
ARG80 COG5068
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 1-215 4.86e-09

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 57.33  E-value: 4.86e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVL------LKYTEYSE 74
Cdd:COG5068  81 VTGRKIGISYITNKTKRSVTFSKRKHGINKKAFELSVLTGTEVLLLVISENGLVHTFTTPKLESVVkslegkSLIQSPCS 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702  75 PHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPPPRiYPVAPAMSVSELSYRVPPATPgcd 154
Cdd:COG5068 161 NAPSDSSEEPSSSASFSVDPNDNNPMGSFQHNGSPQTNFIPLQNPQTQQYQQHSS-RKDHPTVPHSNTNNGRPPAKF--- 236

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28175702 155 pgglgEAPSVHSRPPHFR-PPGLGHPIFSPSHLASKTPPPLYLATDGRRPDLPPGLRSLYSG 215
Cdd:COG5068 237 -----MIPELHSSHSTLDlPSDFISDSGFPNQSSTSIFPLDSAIIQITPPHLPNNPPQENRH 293
PHA03247 PHA03247
large tegument protein UL36; Provisional
 117-338 1.51e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   117 LGGDRGSASPPPRIYPVAPAMSVSELSYRVPpatpgcdpgGLGEAPSVHSRPPHFRPPGLGHPIFSPSHLASKTPPPlyl 196
Cdd:PHA03247 2638 PDPHPPPTVPPPERPRDDPAPGRVSRPRRAR---------RLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPP--- 2705

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   197 atdgRRPDLPPglRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPPTRDAVDPARPVARSLCKEGP 276
Cdd:PHA03247 2706 ----PTPEPAP--HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP 2779

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28175702   277 PSRGASPPTPPVSIKSERLsPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHRLTPDSWP 338
Cdd:PHA03247 2780 PRRLTRPAVASLSESRESL-PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840
PHA03247 PHA03247
large tegument protein UL36; Provisional
 94-329 5.31e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 5.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702    94 GLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPPPRIYPVAPAMSVSELSYRVPPA-----TPGCDPGGLGEAPSVHSRP 168
Cdd:PHA03247 2539 GLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQsarprAPVDDRGDPRGPAPPSPLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   169 PHFRPPglGHPIFSPSHLASKTPPPLYLATDG-----------------------------------RRPDLPPGLRSLY 213
Cdd:PHA03247 2619 PDTHAP--DPPPPSPSPAANEPDPHPPPTVPPperprddpapgrvsrprrarrlgraaqassppqrpRRRAARPTVGSLT 2696

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   214 SgLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQG------PLQPSPWPPTRDAVDPA--RPVARSLCKEGPPSrgASPPT 285
Cdd:PHA03247 2697 S-LADPPPPPPTPEPAPHALVSATPLPPGPAAARqaspalPAAPAPPAVPAGPATPGgpARPARPPTTAGPPA--PAPPA 2773

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 28175702   286 PPVSIKSERLSPVTGTSGDFPR-SFPYPLLLARPLAEPLRPSASL 329
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESReSLPSPWDPADPPAAVLAPAAAL 2818
 
Name Accession Description Interval E-value
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 2-78 3.12e-37

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 128.05  E-value: 3.12e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28175702   2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHES 78
Cdd:cd00265   1 GRGKIEIKRIENSTNRQVTFSKRRNGLLKKAHELSVLCDAEVALIIFSSSGKLYEFSSPSMEKIIERYQKTSGSSLW 77
MADS smart00432
MADS domain;
2-60 2.87e-30

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 109.57  E-value: 2.87e-30
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 28175702      2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASS 60
Cdd:smart00432   1 GRRKIEIKRIENKTNRQVTFSKRRNGLFKKAHELSVLCDAEVALIVFSPTGKLYEFASP 59
MADS cd00120
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ...
 2-60 5.39e-27

MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238067 [Multi-domain]  Cd Length: 59  Bit Score: 100.67  E-value: 5.39e-27
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 28175702   2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASS 60
Cdd:cd00120   1 GRGKIEIKRIENKTSRQVTFSKRRNGLFKKASELSVLCDAEVAVIVFSPSGKLYEFWSS 59
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
 2-83 4.98e-24

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 93.86  E-value: 4.98e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDM-DRVLLKYTEYSEPHESRT 80
Cdd:cd00266   1 GRKKIKIKRIENKKKRAVTFSKRRQGLFKKASELSTLCGAEVAVIVYSPSGKLYVFWPSSEvEGVISRFEVLSALERKKK 80


                ...
gi 28175702  81 NAD 83
Cdd:cd00266  81 AVD 83
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
10-57 3.22e-23

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 90.56  E-value: 3.22e-23
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 28175702    10 RILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQY 57
Cdd:pfam00319   1 RIENKRARQVTFSKRRKGLFKKASELSVLCGAEVAVIVFSPTGKLYTF 48
ARG80 COG5068
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 1-215 4.86e-09

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 57.33  E-value: 4.86e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVL------LKYTEYSE 74
Cdd:COG5068  81 VTGRKIGISYITNKTKRSVTFSKRKHGINKKAFELSVLTGTEVLLLVISENGLVHTFTTPKLESVVkslegkSLIQSPCS 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702  75 PHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPPPRiYPVAPAMSVSELSYRVPPATPgcd 154
Cdd:COG5068 161 NAPSDSSEEPSSSASFSVDPNDNNPMGSFQHNGSPQTNFIPLQNPQTQQYQQHSS-RKDHPTVPHSNTNNGRPPAKF--- 236

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28175702 155 pgglgEAPSVHSRPPHFR-PPGLGHPIFSPSHLASKTPPPLYLATDGRRPDLPPGLRSLYSG 215
Cdd:COG5068 237 -----MIPELHSSHSTLDlPSDFISDSGFPNQSSTSIFPLDSAIIQITPPHLPNNPPQENRH 293
PHA03247 PHA03247
large tegument protein UL36; Provisional
 117-338 1.51e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   117 LGGDRGSASPPPRIYPVAPAMSVSELSYRVPpatpgcdpgGLGEAPSVHSRPPHFRPPGLGHPIFSPSHLASKTPPPlyl 196
Cdd:PHA03247 2638 PDPHPPPTVPPPERPRDDPAPGRVSRPRRAR---------RLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPP--- 2705

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   197 atdgRRPDLPPglRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPPTRDAVDPARPVARSLCKEGP 276
Cdd:PHA03247 2706 ----PTPEPAP--HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP 2779

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28175702   277 PSRGASPPTPPVSIKSERLsPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHRLTPDSWP 338
Cdd:PHA03247 2780 PRRLTRPAVASLSESRESL-PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840
PHA03247 PHA03247
large tegument protein UL36; Provisional
 106-338 6.47e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 6.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   106 PEGPGEKLLR-TLGGDRGSASPPP-------------RIYPVAPAMSVSELSYRVPPATPGCDPGGLGEAPSVHSRPPHF 171
Cdd:PHA03247 2680 PQRPRRRAARpTVGSLTSLADPPPppptpepaphalvSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPAR 2759

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   172 RPPGLGHPIFSPSHLASKTPPPLylATDGRRPDLPPGLRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQP 251
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPPRR--LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   252 SPwPPTRDAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHR 331
Cdd:PHA03247 2838 AP-PPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPP 2916


                  ....*..
gi 28175702   332 LTPDSWP 338
Cdd:PHA03247 2917 PQPQPQP 2923
PHA03247 PHA03247
large tegument protein UL36; Provisional
 115-331 4.71e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 4.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   115 RTLGGDRGSASPPPRIYPVAPAMSVSELSYRVPPATPGCDPgglgEAPSVHSRPPHFRPPG-LGHPIFSPSHLASKTPPP 193
Cdd:PHA03247 2668 RRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP----EPAPHALVSATPLPPGpAAARQASPALPAAPAPPA 2743

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   194 LYLATDGRRPDLPPGLRSLYSGLQSPGAP-GPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPPTRDAVDPARPVARSLC 272
Cdd:PHA03247 2744 VPAGPATPGGPARPARPPTTAGPPAPAPPaAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAAS 2823

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28175702   273 KEGP------PSRGASPPTPPVSIKSERLSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHR 331
Cdd:PHA03247 2824 PAGPlppptsAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLAR 2888
PHA03247 PHA03247
large tegument protein UL36; Provisional
 131-338 4.79e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 4.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   131 YPVAPAmsvselsYRVPP-------ATPGCDPGGLGeaPSVHSRPPhfrPPGLGHPIFSPSHLASKTPPPLY-------- 195
Cdd:PHA03247 2474 FPGAPV-------YRRPAearfpfaAGAAPDPGGGG--PPDPDAPP---APSRLAPAILPDEPVGEPVHPRMltwirgle 2541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   196 -LATD---GRRPDLPPGL------RSLYSGLQSPGAPGPALGSFAFLPS-------GSTDCSPGDAAQGPLQPSPWPPTR 258
Cdd:PHA03247 2542 eLASDdagDPPPPLPPAAppaapdRSVPPPRPAPRPSEPAVTSRARRPDappqsarPRAPVDDRGDPRGPAPPSPLPPDT 2621

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   259 DAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVTgtsgdFPRSfpyplllARPLAEPLRPSASLHRLTPDSWP 338
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVS-----RPRR-------ARRLGRAAQASSPPQRPRRRAAR 2689
PHA03247 PHA03247
large tegument protein UL36; Provisional
 94-329 5.31e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 5.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702    94 GLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPPPRIYPVAPAMSVSELSYRVPPA-----TPGCDPGGLGEAPSVHSRP 168
Cdd:PHA03247 2539 GLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQsarprAPVDDRGDPRGPAPPSPLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   169 PHFRPPglGHPIFSPSHLASKTPPPLYLATDG-----------------------------------RRPDLPPGLRSLY 213
Cdd:PHA03247 2619 PDTHAP--DPPPPSPSPAANEPDPHPPPTVPPperprddpapgrvsrprrarrlgraaqassppqrpRRRAARPTVGSLT 2696

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   214 SgLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQG------PLQPSPWPPTRDAVDPA--RPVARSLCKEGPPSrgASPPT 285
Cdd:PHA03247 2697 S-LADPPPPPPTPEPAPHALVSATPLPPGPAAARqaspalPAAPAPPAVPAGPATPGgpARPARPPTTAGPPA--PAPPA 2773

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 28175702   286 PPVSIKSERLSPVTGTSGDFPR-SFPYPLLLARPLAEPLRPSASL 329
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESReSLPSPWDPADPPAAVLAPAAAL 2818
PHA03247 PHA03247
large tegument protein UL36; Provisional
 121-333 1.16e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 1.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   121 RGSASPPPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEAPSVhSRPPHFRPPGLGHPIFSPSHLASKTPP---PLYLA 197
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA-ALPPAASPAGPLPPPTSAQPTAPPPPPgppPPSLP 2851

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   198 TDG----------RRPDLPPGL------RSLYSGLQSPgAPGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPPTRDAV 261
Cdd:PHA03247 2852 LGGsvapggdvrrRPPSRSPAAkpaapaRPPVRRLARP-AVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ 2930

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28175702   262 DPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHRLT 333
Cdd:PHA03247 2931 PPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLS 3002
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 179-334 5.86e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 38.53  E-value: 5.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28175702   179 PIFSPSHLASKTP-PPLYLATDGRRPDLPPGLRSLYSGLQSPGAPGPALgsfaflPSGSTDCSPGDAAQGPLQPSPwpPT 257
Cdd:PRK10263  743 PLFTPIVEPVQQPqQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQY------QQPQQPVAPQPQYQQPQQPVA--PQ 814

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28175702   258 RDAVDPARPVArslckegPPSRGASPPTPPVSIKSERL-SPVTGTSGDfprsfpyplllARPLAEPLRPSASLHRLTP 334
Cdd:PRK10263  815 PQYQQPQQPVA-------PQPQYQQPQQPVAPQPQDTLlHPLLMRNGD-----------SRPLHKPTTPLPSLDLLTP 874
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH