|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
266-769 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 774.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 266 KTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVSAHTTRVEIDRGRIAEPCSCV--HCHTTHSMALIHNRS 343
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPprECQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 344 FFSDKQMIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPirVNPRVSNVKSVYK--THIDVIHYR 421
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP--YGFKLNTVKGLPVfaTYIEANHVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 422 KTDAKRLHGLDEEAEQKlFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGrgKFRA 501
Cdd:smart00350 159 KLDYKRSFEDSSFSVQS-LSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGM--KIRG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 502 EINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNES 581
Cdd:smart00350 236 DINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDS 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 582 TRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRL 661
Cdd:smart00350 316 DRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDREL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 662 AHHLVSLYYQSEEQVEEEF---LDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIGSSRGMVSAYP---RQLES 735
Cdd:smart00350 396 AKHVVDLHRYSHPEEDEAFeppLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTESRSSIPitvRQLES 475
|
490 500 510
....*....|....*....|....*....|....
gi 15341837 736 LIRLAEAHAKVRFSNKVEAIDVEEAKRLHREALK 769
Cdd:smart00350 476 IIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
192-849 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 616.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 192 YMQQLGEI--NITGEPFLNVNCEHIKSFSKNLYRQLISYPQEVIPTFDMAVNEIffDRYPDSILEHQIQVRPFNALKTKS 269
Cdd:COG1241 18 YRDEILELaqEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREI--DLEPYDVSLGDAHVRITNLPETVP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 270 MRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVSAHTTRVEIDRGRIAEPCSCVHCHTTHSMALIHNRSFFSDKQ 349
Cdd:COG1241 96 IRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQGPFKLLPEKSEFIDAQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 350 MIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVnprvSNVKS-VYKTHIDVIHYRKTDaKRL 428
Cdd:COG1241 176 KIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTS----GRGKStIFDLYLEANSIEVEE-KEF 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 429 hgldEEAEqklFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRK---DFSHTgrgkfRAEINI 505
Cdd:COG1241 251 ----EEIE---ITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKvlpDGSRI-----RGDIHI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 506 LLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPE-TRQLVLQTGALVLSDNGICCIDEFDKMNESTRS 584
Cdd:COG1241 319 LLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRS 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 585 VLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHH 664
Cdd:COG1241 399 ALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARH 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 665 LVSLYY------QSEEQVEEEF---LDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIGSSR-GMVSAYPRQLE 734
Cdd:COG1241 479 ILKVHRagelleQEIEEETEEVkpeIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFYVDMRKKGEDEdSPVPITARQLE 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 735 SLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALRKLiLSKGKT 814
Cdd:COG1241 559 ALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFDIDVIETGTSKSQRDKMKLIKDIIKEL-EEESSG 637
|
650 660 670
....*....|....*....|....*....|....*
gi 15341837 815 PAlKYQQLFEDIRGQsdtAITKDMFEEALRALADD 849
Cdd:COG1241 638 GA-PIEDVIEEAEEE---GIDREKAEELIEKLKRK 668
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
460-767 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 601.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 460 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFsHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 539
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDF-TKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 540 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 619
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 620 ESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQS-EEQVEEEFLDMAVLKDYIAYAHSTIM 698
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDtPEHIQDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 699 PRLSEEASQALIEAYVNMRKIGSS-RGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREA 767
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKMGSDaRKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
162-846 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 556.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 162 KENFQRFLQCFTDPLAKEEenvgiditqplYMQQLGEINITGEPFLNVNCEHIKSFSKNLYRQLISYPQEVIPTFDMAVN 241
Cdd:NF040949 2 GEKFKEFIRTFRDSFGNEK-----------YKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALK 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 242 EIFFDRYPDSILEHQ-IQVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVSAHTTRV----EI 316
Cdd:NF040949 71 EIVEEEDPEYAEEVAkFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWpeeeEE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 317 DRGRIAEPCSCVHCHTTHSMALIHNRSFFSDKQMIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAV 396
Cdd:NF040949 151 SYEIVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 397 PIRVNPRvsNVKSVYKTHIDVIHYrktdakrlhgldeEAEQKLF-----SEKRVKLLKELSRKPDIYERLASALAPSIYE 471
Cdd:NF040949 231 PDSSLKK--GSRPIFKNYIEANHI-------------EVSQKELeeveiTEEDEEKILELAKDPWIREKIIASIAPSIYG 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 472 HEDIKKGILLQLFGGTRKDFSHTGRgkFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPE 551
Cdd:NF040949 296 HWEIKEAIALLLFGGVPKVLPDGTR--IRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKL 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 552 TRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIE 631
Cdd:NF040949 374 TGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAE 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 632 NIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLyYQSEEQVEEEfLDMAVLKDYIAYAHSTIMPRLSEEASQALIE 711
Cdd:NF040949 454 NIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDV-HSGKEKVKPE-IDPDLLKKYIAYARKYVRPKLTEEAKKLIED 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 712 AYVNMRK-IGSSRGMVSAYP---RQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTT 787
Cdd:NF040949 532 FYVEMRKsSKSSEDPDSPIPitaRQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETGKIDIDTIMT 611
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 15341837 788 GMSATSRKRKEELAEALRKLILSKGKTPalkyqqLFEDIRGQSDTAITKDMFEEALRAL 846
Cdd:NF040949 612 GKPKSKREKMSKIVEIIKELEEEEECVK------IKELIKEAEKKGIDEEKVEELISDL 664
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
155-846 |
1.16e-161 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 494.90 E-value: 1.16e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 155 DVNVATCKENFQRFLQCFT---DPLAKEEENVGIDITQPLY----MQQLGEINITGE--------PFlNVNCEHIKSFSK 219
Cdd:PTZ00111 82 DNRLEELSERFTNFLKNFTefsDVLEFKDEQQSKPEYTELYylwkLMNFIKENLRDHstgysrilPF-EVDLMHVYSFDK 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 220 NLYRQLISYPQEVIPTFDMAV----NEIFFDRYPDSILEHQI---QVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTS 292
Cdd:PTZ00111 161 VLYKLLVTFPADCIAELDKVLvklfNELLSKHYSDLSLENNSffpRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQT 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 293 QLIPEMQEAFFQCQVSAHTTRVEID-----------RGRIAEPCSCVHCHTTHSMALIHNRSFFSDKQMIKLQESPEDMP 361
Cdd:PTZ00111 241 WIVPEITMACFRCRGQKKIGLNDYQpctcehyeyviQGEVNEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLN 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 362 AGQTP--------------------HTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYR 421
Cdd:PTZ00111 321 NPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNVIHVK 400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 422 ---KTDAKR-LHGLDEEAEQKLFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGG--TRKDFSHTG 495
Cdd:PTZ00111 401 vinSTNANQpEKGLKYLGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGnkNSSDFNKSP 480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 496 RG-----KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYV-MKDPETRQLVLQTGALVLSDNGI 569
Cdd:PTZ00111 481 DAcykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGV 560
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 570 CCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLM 649
Cdd:PTZ00111 561 CCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLV 640
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 650 LDPQDE---------------------------AYDRRLAHHLVSLYYQSEEQVEEEFLDMavLKDYIAYAHSTIMPRLS 702
Cdd:PTZ00111 641 LDHIDQdtdqlislsiakdfllphmtgsgndedTYDRSNTMHVEDESLRSEKDYNKNDLDM--LRMYIKFSKLHCFPKLS 718
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 703 EEASQALIEAYVNMRKIG------------------------SSRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVE 758
Cdd:PTZ00111 719 DEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyqsSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADAL 798
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 759 EAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALRKLILSKGKTPALKYQQL----------FEDIRG 828
Cdd:PTZ00111 799 QAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQMYEQVLSVLTRSSNQDSNKSLDLnevlslchktFKDNRD 878
|
810
....*....|....*...
gi 15341837 829 QSDTAITKdMFEEALRAL 846
Cdd:PTZ00111 879 HKDGEIYK-LISEVLNKM 895
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
444-669 |
1.35e-136 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 405.38 E-value: 1.35e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 444 RVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKdfSHTGRGKFRAEINILLCGDPGTSKSQLLQYVY 523
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKK--ILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 524 NLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGII 603
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15341837 604 CQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLY 669
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
162-263 |
1.25e-18 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 81.57 E-value: 1.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 162 KENFQRFLQCFTDPLAKEeenvgiditqPLYMQQLGEINITGEPFLNVNCEHIKSFSKNLYRQLISYPQEVIPTFDMAVN 241
Cdd:pfam14551 1 KRKFKDFLEEFREDGDGE----------FKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALK 70
|
90 100
....*....|....*....|....*
gi 15341837 242 EIFFDRYPDS---ILEHQIQVRPFN 263
Cdd:pfam14551 71 EVVKELSEDPdyaEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
266-769 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 774.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 266 KTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVSAHTTRVEIDRGRIAEPCSCV--HCHTTHSMALIHNRS 343
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPprECQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 344 FFSDKQMIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPirVNPRVSNVKSVYK--THIDVIHYR 421
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP--YGFKLNTVKGLPVfaTYIEANHVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 422 KTDAKRLHGLDEEAEQKlFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGrgKFRA 501
Cdd:smart00350 159 KLDYKRSFEDSSFSVQS-LSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGM--KIRG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 502 EINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNES 581
Cdd:smart00350 236 DINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDS 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 582 TRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRL 661
Cdd:smart00350 316 DRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDREL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 662 AHHLVSLYYQSEEQVEEEF---LDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIGSSRGMVSAYP---RQLES 735
Cdd:smart00350 396 AKHVVDLHRYSHPEEDEAFeppLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTESRSSIPitvRQLES 475
|
490 500 510
....*....|....*....|....*....|....
gi 15341837 736 LIRLAEAHAKVRFSNKVEAIDVEEAKRLHREALK 769
Cdd:smart00350 476 IIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
192-849 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 616.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 192 YMQQLGEI--NITGEPFLNVNCEHIKSFSKNLYRQLISYPQEVIPTFDMAVNEIffDRYPDSILEHQIQVRPFNALKTKS 269
Cdd:COG1241 18 YRDEILELaqEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREI--DLEPYDVSLGDAHVRITNLPETVP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 270 MRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVSAHTTRVEIDRGRIAEPCSCVHCHTTHSMALIHNRSFFSDKQ 349
Cdd:COG1241 96 IRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQGPFKLLPEKSEFIDAQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 350 MIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVnprvSNVKS-VYKTHIDVIHYRKTDaKRL 428
Cdd:COG1241 176 KIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTS----GRGKStIFDLYLEANSIEVEE-KEF 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 429 hgldEEAEqklFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRK---DFSHTgrgkfRAEINI 505
Cdd:COG1241 251 ----EEIE---ITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKvlpDGSRI-----RGDIHI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 506 LLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPE-TRQLVLQTGALVLSDNGICCIDEFDKMNESTRS 584
Cdd:COG1241 319 LLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRS 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 585 VLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHH 664
Cdd:COG1241 399 ALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARH 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 665 LVSLYY------QSEEQVEEEF---LDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIGSSR-GMVSAYPRQLE 734
Cdd:COG1241 479 ILKVHRagelleQEIEEETEEVkpeIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFYVDMRKKGEDEdSPVPITARQLE 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 735 SLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALRKLiLSKGKT 814
Cdd:COG1241 559 ALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFDIDVIETGTSKSQRDKMKLIKDIIKEL-EEESSG 637
|
650 660 670
....*....|....*....|....*....|....*
gi 15341837 815 PAlKYQQLFEDIRGQsdtAITKDMFEEALRALADD 849
Cdd:COG1241 638 GA-PIEDVIEEAEEE---GIDREKAEELIEKLKRK 668
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
460-767 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 601.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 460 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFsHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 539
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDF-TKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 540 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 619
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 620 ESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQS-EEQVEEEFLDMAVLKDYIAYAHSTIM 698
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDtPEHIQDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 699 PRLSEEASQALIEAYVNMRKIGSS-RGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREA 767
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKMGSDaRKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
162-846 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 556.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 162 KENFQRFLQCFTDPLAKEEenvgiditqplYMQQLGEINITGEPFLNVNCEHIKSFSKNLYRQLISYPQEVIPTFDMAVN 241
Cdd:NF040949 2 GEKFKEFIRTFRDSFGNEK-----------YKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALK 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 242 EIFFDRYPDSILEHQ-IQVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVSAHTTRV----EI 316
Cdd:NF040949 71 EIVEEEDPEYAEEVAkFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWpeeeEE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 317 DRGRIAEPCSCVHCHTTHSMALIHNRSFFSDKQMIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAV 396
Cdd:NF040949 151 SYEIVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 397 PIRVNPRvsNVKSVYKTHIDVIHYrktdakrlhgldeEAEQKLF-----SEKRVKLLKELSRKPDIYERLASALAPSIYE 471
Cdd:NF040949 231 PDSSLKK--GSRPIFKNYIEANHI-------------EVSQKELeeveiTEEDEEKILELAKDPWIREKIIASIAPSIYG 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 472 HEDIKKGILLQLFGGTRKDFSHTGRgkFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPE 551
Cdd:NF040949 296 HWEIKEAIALLLFGGVPKVLPDGTR--IRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKL 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 552 TRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIE 631
Cdd:NF040949 374 TGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAE 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 632 NIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLyYQSEEQVEEEfLDMAVLKDYIAYAHSTIMPRLSEEASQALIE 711
Cdd:NF040949 454 NIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDV-HSGKEKVKPE-IDPDLLKKYIAYARKYVRPKLTEEAKKLIED 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 712 AYVNMRK-IGSSRGMVSAYP---RQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTT 787
Cdd:NF040949 532 FYVEMRKsSKSSEDPDSPIPitaRQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETGKIDIDTIMT 611
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 15341837 788 GMSATSRKRKEELAEALRKLILSKGKTPalkyqqLFEDIRGQSDTAITKDMFEEALRAL 846
Cdd:NF040949 612 GKPKSKREKMSKIVEIIKELEEEEECVK------IKELIKEAEKKGIDEEKVEELISDL 664
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
155-846 |
1.16e-161 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 494.90 E-value: 1.16e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 155 DVNVATCKENFQRFLQCFT---DPLAKEEENVGIDITQPLY----MQQLGEINITGE--------PFlNVNCEHIKSFSK 219
Cdd:PTZ00111 82 DNRLEELSERFTNFLKNFTefsDVLEFKDEQQSKPEYTELYylwkLMNFIKENLRDHstgysrilPF-EVDLMHVYSFDK 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 220 NLYRQLISYPQEVIPTFDMAV----NEIFFDRYPDSILEHQI---QVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTS 292
Cdd:PTZ00111 161 VLYKLLVTFPADCIAELDKVLvklfNELLSKHYSDLSLENNSffpRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQT 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 293 QLIPEMQEAFFQCQVSAHTTRVEID-----------RGRIAEPCSCVHCHTTHSMALIHNRSFFSDKQMIKLQESPEDMP 361
Cdd:PTZ00111 241 WIVPEITMACFRCRGQKKIGLNDYQpctcehyeyviQGEVNEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLN 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 362 AGQTP--------------------HTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYR 421
Cdd:PTZ00111 321 NPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNVIHVK 400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 422 ---KTDAKR-LHGLDEEAEQKLFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGG--TRKDFSHTG 495
Cdd:PTZ00111 401 vinSTNANQpEKGLKYLGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGnkNSSDFNKSP 480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 496 RG-----KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYV-MKDPETRQLVLQTGALVLSDNGI 569
Cdd:PTZ00111 481 DAcykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGV 560
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 570 CCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLM 649
Cdd:PTZ00111 561 CCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLV 640
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 650 LDPQDE---------------------------AYDRRLAHHLVSLYYQSEEQVEEEFLDMavLKDYIAYAHSTIMPRLS 702
Cdd:PTZ00111 641 LDHIDQdtdqlislsiakdfllphmtgsgndedTYDRSNTMHVEDESLRSEKDYNKNDLDM--LRMYIKFSKLHCFPKLS 718
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 703 EEASQALIEAYVNMRKIG------------------------SSRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVE 758
Cdd:PTZ00111 719 DEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyqsSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADAL 798
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 759 EAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALRKLILSKGKTPALKYQQL----------FEDIRG 828
Cdd:PTZ00111 799 QAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQMYEQVLSVLTRSSNQDSNKSLDLnevlslchktFKDNRD 878
|
810
....*....|....*...
gi 15341837 829 QSDTAITKdMFEEALRAL 846
Cdd:PTZ00111 879 HKDGEIYK-LISEVLNKM 895
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
460-767 |
7.87e-137 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 409.43 E-value: 7.87e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 460 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFShtGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 539
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILE--DGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 540 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 619
Cdd:cd17706 79 AGLTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 620 ESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLY--YQSEEQVEEEF----LDMAVLKDYIAYA 693
Cdd:cd17706 159 GGRYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHrgSDPEEQVKPEEdgipIDIELLRKYILYA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15341837 694 hSTIMPRLSEEASQALIEAYVNMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREA 767
Cdd:cd17706 239 -RQIHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
444-669 |
1.35e-136 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 405.38 E-value: 1.35e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 444 RVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKdfSHTGRGKFRAEINILLCGDPGTSKSQLLQYVY 523
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKK--ILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 524 NLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGII 603
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15341837 604 CQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLY 669
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
460-763 |
1.44e-124 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 377.52 E-value: 1.44e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 460 RLASALAPSIYEHEDIKKGILLQLFGGTRKdfshTGRG-KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSS 538
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDK----RGDGmKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 539 AVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANP 618
Cdd:cd17758 77 GVGLTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 619 IESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHlVSLYYQSEEQVEEEF--LDMAVLKDYIAYAhST 696
Cdd:cd17758 157 AYGRYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEH-VTYVHQHNKQPDSDFepLDPKLLRAYIALA-KR 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15341837 697 IMPRLSEEASQALIEAYVNMRKiGSSRGMVSAY--PRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRL 763
Cdd:cd17758 235 KRPTVPPALADYIVQAYVEMRQ-EAKRSKDFTFttPRTLLAILRLSQALARLRLSDSVEIDDVEEALRL 302
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
460-771 |
2.96e-122 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 371.32 E-value: 2.96e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 460 RLASALAPSIYEHEDIKKGILLQLFGGTRKdfSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 539
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHK--ITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 540 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 619
Cdd:cd17757 79 AGLTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 620 ESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQSEEQVEEEFlDMAVLKDYIAYAHsTIMP 699
Cdd:cd17757 159 GGRYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAIEPPF-TAEQLKRYIAYAR-TFKP 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15341837 700 RLSEEASQALIEAYVNMRKIGSSRGMVSAYP---RQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLhreaLKQS 771
Cdd:cd17757 237 KLTKEAKDELVEQYKELRQDDASGSTRSSYRitvRQLESLIRLSEAIARLHCSDEVTPEHVEEAARL----LKKS 307
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
460-763 |
1.48e-120 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 367.48 E-value: 1.48e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 460 RLASALAPSIYEHEDIKKGILLQLFGGTRKdfsHTGRG-KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSS 538
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRK---RLPDGmRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 539 AVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANP 618
Cdd:cd17756 78 AAGLTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 619 IESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYY----QSEEQVEEEFLDMAVLKDYIAYAH 694
Cdd:cd17756 158 VFGRYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHAsarkASQSQENEGEIPISKLKRYIAYCR 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15341837 695 STIMPRLSEEASQALIEAYVNMRK----IGSSRGMVSAYP---RQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRL 763
Cdd:cd17756 238 AKCAPRLSEEAAEKLSNHYVTIRKdvrqNELESDNRSSIPitvRQLEAIIRISESLAKMELSPIATEKHVEEAIRL 313
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
459-765 |
8.25e-114 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 349.44 E-value: 8.25e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 459 ERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRgkFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSS 538
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTR--IRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGST 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 539 AVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANP 618
Cdd:cd17761 79 AAGLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 619 IESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQSEEQVEEEFLDMAVLKDYIAYAHSTIM 698
Cdd:cd17761 159 KFGRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPEIDPDLLRKYIAYARKNVR 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15341837 699 PRLSEEASQALIEAYVNMRKIGSSRGM-VSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHR 765
Cdd:cd17761 239 PVLTEEAKQLIKDFYVEMRKSGQETPSpVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
461-767 |
8.23e-108 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 333.66 E-value: 8.23e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 461 LASALAPSIYEHEDIKKGILLQLFGGTRKDFshTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAV 540
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNL--ENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 541 GLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIE 620
Cdd:cd17754 80 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 621 SQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQseeqveeefldMAVLKDYIAYAHSTIMPR 700
Cdd:cd17754 160 GRYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY-----------IKFLRKYIHYAKERIKPK 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15341837 701 LSEEASQALIEAYVNMRKIGS----SRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREA 767
Cdd:cd17754 229 LTQEAAEYIAEEYADLRNDDNtktdKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
460-763 |
3.12e-103 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 322.48 E-value: 3.12e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 460 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFShtGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 539
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPG--GKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 540 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 619
Cdd:cd17753 79 VGLTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 620 ESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQSEEQVEE-------------------EF 680
Cdd:cd17753 159 GGRYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEdregeeeknqrqrpketkvEP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 681 LDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEA 760
Cdd:cd17753 239 IPQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMA 318
|
...
gi 15341837 761 KRL 763
Cdd:cd17753 319 IRV 321
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
460-767 |
6.14e-89 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 283.66 E-value: 6.14e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 460 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 539
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 540 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNeSTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 619
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMG-SQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 620 ESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHlvslyyqseeqveeefldMAVLKDYIAYAHSTIMP 699
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH------------------HQLLRKYISYARQYVNP 221
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15341837 700 RLSEEASQALIEAYVNMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREA 767
Cdd:cd17759 222 VLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
461-757 |
1.31e-75 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 248.61 E-value: 1.31e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 461 LASALAPSIYEHEDIKKGILLQLFGGT-RKDFSHTgrgKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 539
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVqRIDASGT---RVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 540 VGLTAYVMKDpeTRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPi 619
Cdd:cd17760 79 AGLTVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 620 ESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHhlVSLYYQSEEQVEEEFLDMAVLKDYIAYAhSTIMP 699
Cdd:cd17760 156 KGQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISS--FILENKGEPSKSSKLWSMEKMRTYFCLI-KNLRP 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 15341837 700 RLSEEASQALIeAYVNMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDV 757
Cdd:cd17760 233 VLSDEANAILL-RYYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDA 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
269-397 |
1.18e-50 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 173.82 E-value: 1.18e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 269 SMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVSAHTTRVeidrgRIAEP--CSCVHCHTTHSMALIHNRSFFS 346
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGV-----KITEPtkCPNPECGNKDPFKLVHEKSKFV 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 15341837 347 DKQMIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVP 397
Cdd:pfam17207 76 DFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
686-768 |
2.41e-30 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 114.56 E-value: 2.41e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 686 LKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIGS-SRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLH 764
Cdd:pfam17855 3 LRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTgSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIRLL 82
|
....
gi 15341837 765 REAL 768
Cdd:pfam17855 83 KESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
162-263 |
1.25e-18 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 81.57 E-value: 1.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 162 KENFQRFLQCFTDPLAKEeenvgiditqPLYMQQLGEINITGEPFLNVNCEHIKSFSKNLYRQLISYPQEVIPTFDMAVN 241
Cdd:pfam14551 1 KRKFKDFLEEFREDGDGE----------FKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALK 70
|
90 100
....*....|....*....|....*
gi 15341837 242 EIFFDRYPDS---ILEHQIQVRPFN 263
Cdd:pfam14551 71 EVVKELSEDPdyaEEEKEFQVRFYN 95
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
504-643 |
8.12e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 43.44 E-value: 8.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 504 NILLCGDPGTSKSQLLQYVYNLVPRGQYTsgkgssAVGLTAYVMKDPETRQLVLQTGALVLSDN---------GICCIDE 574
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVF------YVQLTRDTTEEDLFGRRNIDPGGASWVDGplvraaregEIAVLDE 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 575 FDKMNESTRSVLHEVMEQQTLSIAKAGIICQL-NARTSVLAAANPIESQWNPkkttieniqLPHTLLSRF 643
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERRLLLPDGGELVKAaPDGFRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
504-649 |
2.46e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 42.13 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 504 NILLCGDPGTSKSQLLQYVYNLVPRGQYT--SGKGSSAVGLTAYVMKDpETRQLVLQTGALVLSDNGICCIDEFDKMNES 581
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPGAPflYLNASDLLEGLVVAELF-GHFLVRLLFELAEKAKPGVLFIDEIDSLSRG 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15341837 582 TRSVLHEVMEQQTLSIAKagiicqlNARTSVLAAANPIESqwnpkkttienIQLPHTLLSRFDLIFLM 649
Cdd:cd00009 100 AQNALLRVLETLNDLRID-------RENVRVIGATNRPLL-----------GDLDRALYDRLDIRIVI 149
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
505-769 |
2.96e-03 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 40.54 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 505 ILLCGDPGTSKSQLLQYV-------YNLVprgQYTSG-KGSSAVGLTAYvmkDPETRQLVLQTGAL----VLsdngiccI 572
Cdd:COG0714 34 LLLEGVPGVGKTTLAKALaralglpFIRI---QFTPDlLPSDILGTYIY---DQQTGEFEFRPGPLfanvLL-------A 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 573 DEFDKMNESTRSVLHEVMEQQTLSIakAGIICQLNARTSVLAAANPIESQwnpkkTTIEniqLPHTLLSRFdLIFLMLDP 652
Cdd:COG0714 101 DEINRAPPKTQSALLEAMEERQVTI--PGGTYKLPEPFLVIATQNPIEQE-----GTYP---LPEAQLDRF-LLKLYIGY 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15341837 653 QDEaydrrlahhlvslyyqseeqvEEEfldMAVLKDYIAYAHSTIMPRLSEEASQAL------------IEAYVnMRKIG 720
Cdd:COG0714 170 PDA---------------------EEE---REILRRHTGRHLAEVEPVLSPEELLALqelvrqvhvseaVLDYI-VDLVR 224
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 15341837 721 SSRGMVSAY----PRQLESLIRLAEAHAKVRFSNKVEAIDVeeaKRLHREALK 769
Cdd:COG0714 225 ATREHPDLRkgpsPRASIALLRAARALALLDGRDYVTPDDV---KAVAGPVLK 274
|
|
| |
