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Conserved domains on  [gi|15082415|gb|AAH12123|]
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Golgi phosphoprotein 3 (coat-protein) [Homo sapiens]

Protein Classification

GPP34 family phosphoprotein( domain architecture ID 10529731)

golgi phosphoprotein 3 (GPP34) family protein similar to eukaryotic GPP34, whose functions include a role in golgi membrane trafficking, anterograde transport from the golgi to the plasma membrane, cell migration, and regulation of mitochondrial lipids biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GPP34 pfam05719
Golgi phosphoprotein 3 (GPP34); This family consists of several eukaryotic GPP34 like proteins. ...
 62-273 6.68e-50

Golgi phosphoprotein 3 (GPP34); This family consists of several eukaryotic GPP34 like proteins. GPP34 localizes to the Golgi complex and is conserved from yeast to humans. The cytosolic-ally exposed location of GPP34 predict a role for a novel coat protein in Golgi trafficking.


:

Pssm-ID: 428605  Cd Length: 198  Bit Score: 164.03  E-value: 6.68e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15082415    62 LMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGmrrkslltRKVICKSDAPTGDVLLDEALKHVK 141
Cdd:pfam05719   1 LAEELLLLALDDESGRPSLGARALSYALAGALLLELALAGRVAVDGEG--------GRVVVVDPRPTGDPLLDEALALLK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15082415   142 ETQPPETVQNWIELLSgetwnplklhyqlRNVRERLAKNLVEKGVLTTEKQNFL-LFDMTTHPLTNNNIKQRLIKKVQEA 220
Cdd:pfam05719  73 AEKRPRKVKDWLRKLS-------------RGLRERVLARLVAKGVLRRERRRVLgLFPRTRYPVVDPAAEAALRARLRAA 139

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 15082415   221 VLDKWVNDPhrmdrRLLALIYLAHASDVLENAFApllDEQYDLATKRVRQLLD 273
Cdd:pfam05719 140 LLGGEPPDP-----RTAALAALLAAAGLLRKVLP---DLERRRARARAKELLE 184
 
Name Accession Description Interval E-value
GPP34 pfam05719
Golgi phosphoprotein 3 (GPP34); This family consists of several eukaryotic GPP34 like proteins. ...
 62-273 6.68e-50

Golgi phosphoprotein 3 (GPP34); This family consists of several eukaryotic GPP34 like proteins. GPP34 localizes to the Golgi complex and is conserved from yeast to humans. The cytosolic-ally exposed location of GPP34 predict a role for a novel coat protein in Golgi trafficking.


Pssm-ID: 428605  Cd Length: 198  Bit Score: 164.03  E-value: 6.68e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15082415    62 LMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGmrrkslltRKVICKSDAPTGDVLLDEALKHVK 141
Cdd:pfam05719   1 LAEELLLLALDDESGRPSLGARALSYALAGALLLELALAGRVAVDGEG--------GRVVVVDPRPTGDPLLDEALALLK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15082415   142 ETQPPETVQNWIELLSgetwnplklhyqlRNVRERLAKNLVEKGVLTTEKQNFL-LFDMTTHPLTNNNIKQRLIKKVQEA 220
Cdd:pfam05719  73 AEKRPRKVKDWLRKLS-------------RGLRERVLARLVAKGVLRRERRRVLgLFPRTRYPVVDPAAEAALRARLRAA 139

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 15082415   221 VLDKWVNDPhrmdrRLLALIYLAHASDVLENAFApllDEQYDLATKRVRQLLD 273
Cdd:pfam05719 140 LLGGEPPDP-----RTAALAALLAAAGLLRKVLP---DLERRRARARAKELLE 184
 
Name Accession Description Interval E-value
GPP34 pfam05719
Golgi phosphoprotein 3 (GPP34); This family consists of several eukaryotic GPP34 like proteins. ...
 62-273 6.68e-50

Golgi phosphoprotein 3 (GPP34); This family consists of several eukaryotic GPP34 like proteins. GPP34 localizes to the Golgi complex and is conserved from yeast to humans. The cytosolic-ally exposed location of GPP34 predict a role for a novel coat protein in Golgi trafficking.


Pssm-ID: 428605  Cd Length: 198  Bit Score: 164.03  E-value: 6.68e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15082415    62 LMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGmrrkslltRKVICKSDAPTGDVLLDEALKHVK 141
Cdd:pfam05719   1 LAEELLLLALDDESGRPSLGARALSYALAGALLLELALAGRVAVDGEG--------GRVVVVDPRPTGDPLLDEALALLK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15082415   142 ETQPPETVQNWIELLSgetwnplklhyqlRNVRERLAKNLVEKGVLTTEKQNFL-LFDMTTHPLTNNNIKQRLIKKVQEA 220
Cdd:pfam05719  73 AEKRPRKVKDWLRKLS-------------RGLRERVLARLVAKGVLRRERRRVLgLFPRTRYPVVDPAAEAALRARLRAA 139

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 15082415   221 VLDKWVNDPhrmdrRLLALIYLAHASDVLENAFApllDEQYDLATKRVRQLLD 273
Cdd:pfam05719 140 LLGGEPPDP-----RTAALAALLAAAGLLRKVLP---DLERRRARARAKELLE 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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