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Conserved domains on  [gi|1020307|gb|AAA89162|]
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FK506 binding protein 51 [Mus musculus]

Protein Classification

FKBP_C and TPR domain-containing protein( domain architecture ID 11991378)

FKBP_C and TPR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
44-135 7.56e-38

FKBP-type peptidyl-prolyl cis-trans isomerase;


:

Pssm-ID: 459735  Cd Length: 94  Bit Score: 133.09  E-value: 7.56e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307     44 DEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQ-KI 122
Cdd:pfam00254   2 PEKAKKGDRVTVHYTGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGpVI 81

                          90
                  ....*....|...
gi 1020307    123 PSNATLFFEIELL 135
Cdd:pfam00254  82 PPNATLVFEVELL 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
274-403 3.90e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 3.90e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  274 KGTVYFKGGKYTQAVIQYRKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKG 353
Cdd:COG0457  14 LGLAYRRLGRYEEAIEDYEKA---LELDPDDAE------------ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 1020307  354 LYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG0457  79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128
 
Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
44-135 7.56e-38

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 133.09  E-value: 7.56e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307     44 DEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQ-KI 122
Cdd:pfam00254   2 PEKAKKGDRVTVHYTGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGpVI 81

                          90
                  ....*....|...
gi 1020307    123 PSNATLFFEIELL 135
Cdd:pfam00254  82 PPNATLVFEVELL 94
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
 36-137 1.78e-37

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 132.23  E-value: 1.78e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307   36 IVKRVGTSdEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGS 115
Cdd:COG0545   4 KVLKEGTG-AKPKAGDTVTVHYTGTLLDGTVFDSSYDRGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPELAYGE 82

                        90       100
                ....*....|....*....|..
gi 1020307  116 AGHLQKIPSNATLFFEIELLDF 137
Cdd:COG0545  83 RGAGGVIPPNSTLVFEVELLDV 104
PRK10902 PRK10902
FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional
 28-138 3.85e-22

FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 236791 [Multi-domain]  Cd Length: 269  Bit Score: 95.60  E-value: 3.85e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    28 KKDRGVLKIVKRVGTSDeAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLgqGQVIKAWDIGVSTMKKGEICHLLC 107
Cdd:PRK10902 143 TTSTGLLYKVEKEGTGE-APKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRL--DGVIPGWTEGLKNIKKGGKIKLVI 219

                         90       100       110
                 ....*....|....*....|....*....|.
gi 1020307   108 KPEYAYGSAGhLQKIPSNATLFFEIELLDFK 138
Cdd:PRK10902 220 PPELAYGKAG-VPGIPANSTLVFDVELLDVK 249
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
274-403 3.90e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 3.90e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  274 KGTVYFKGGKYTQAVIQYRKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKG 353
Cdd:COG0457  14 LGLAYRRLGRYEEAIEDYEKA---LELDPDDAE------------ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 1020307  354 LYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG0457  79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 230-397 9.13e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 54.60  E-value: 9.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    230 KPKF-GIDPNAELMYEVTLKSFEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEY-GLSEK 307
Cdd:TIGR00990 274 KPRPaGLEDSNELDEETGNGQLQLGLKSPESKADESYEEAARAFEKALDLGKLGEKEAIALNLRGTFKCLKGKHlEALAD 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    308 ESKASESF--LLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNR 385
Cdd:TIGR00990 354 LSKSIELDprVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFI 433

                         170
                  ....*....|..
gi 1020307    386 AARLQISMCQRK 397
Cdd:TIGR00990 434 FSHIQLGVTQYK 445
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 319-350 3.66e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 43.20  E-value: 3.66e-06
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1020307     319 AFLNLAMCYLKLREYNKAVECCDKALGLDSAN 350
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
319-347 5.10e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.79  E-value: 5.10e-06
                          10        20
                  ....*....|....*....|....*....
gi 1020307    319 AFLNLAMCYLKLREYNKAVECCDKALGLD 347
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELN 31
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 305-403 1.86e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 43.62  E-value: 1.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307   305 SEKESKASESFL-----LAA----------------FLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Cdd:PLN03088   3 KDLEDKAKEAFVdddfaLAVdlytqaidldpnnaelYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMK 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 1020307   364 MNDFESAKGDFEKVLAVNPQN-RAARLqISMCQRKAKEHNE 403
Cdd:PLN03088  83 LEEYQTAKAALEKGASLAPGDsRFTKL-IKECDEKIAEEEK 122
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 318-382 8.50e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.07  E-value: 8.50e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1020307  318 AAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNP 382
Cdd:cd24142   1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
 
Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
44-135 7.56e-38

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 133.09  E-value: 7.56e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307     44 DEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQ-KI 122
Cdd:pfam00254   2 PEKAKKGDRVTVHYTGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGpVI 81

                          90
                  ....*....|...
gi 1020307    123 PSNATLFFEIELL 135
Cdd:pfam00254  82 PPNATLVFEVELL 94
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
 36-137 1.78e-37

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 132.23  E-value: 1.78e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307   36 IVKRVGTSdEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGS 115
Cdd:COG0545   4 KVLKEGTG-AKPKAGDTVTVHYTGTLLDGTVFDSSYDRGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPELAYGE 82

                        90       100
                ....*....|....*....|..
gi 1020307  116 AGHLQKIPSNATLFFEIELLDF 137
Cdd:COG0545  83 RGAGGVIPPNSTLVFEVELLDV 104
PRK10902 PRK10902
FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional
 28-138 3.85e-22

FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 236791 [Multi-domain]  Cd Length: 269  Bit Score: 95.60  E-value: 3.85e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    28 KKDRGVLKIVKRVGTSDeAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLgqGQVIKAWDIGVSTMKKGEICHLLC 107
Cdd:PRK10902 143 TTSTGLLYKVEKEGTGE-APKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRL--DGVIPGWTEGLKNIKKGGKIKLVI 219

                         90       100       110
                 ....*....|....*....|....*....|.
gi 1020307   108 KPEYAYGSAGhLQKIPSNATLFFEIELLDFK 138
Cdd:PRK10902 220 PPELAYGKAG-VPGIPANSTLVFDVELLDVK 249
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
274-403 3.90e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 3.90e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  274 KGTVYFKGGKYTQAVIQYRKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKG 353
Cdd:COG0457  14 LGLAYRRLGRYEEAIEDYEKA---LELDPDDAE------------ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 1020307  354 LYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG0457  79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
275-403 2.06e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 72.73  E-value: 2.06e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  275 GTVYFKGGKYTQAVIQYRKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGL 354
Cdd:COG0457  49 GLAYLRLGRYEEALADYEQA---LELDPDDAE------------ALNNLGLALQALGRYEEALEDYDKALELDPDDAEAL 113

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 1020307  355 YRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG0457 114 YNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 250-403 1.07e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.91  E-value: 1.07e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  250 FEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVswlemeyglsekeskASESFLLAAFLNLAMCYLK 329
Cdd:COG2956  58 YDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLL---------------ELDPDDAEALRLLAEIYEQ 122

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1020307  330 LREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG2956 123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
319-403 3.68e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 66.18  E-value: 3.68e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  319 AFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKA 398
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89


                ....*
gi 1020307  399 KEHNE 403
Cdd:COG0457  90 GRYEE 94
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
268-406 3.97e-12

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 65.71  E-value: 3.97e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  268 AAIVKEKGTVYFKGGKYTQAVIQYRKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYNKAVECCDKALGLD 347
Cdd:COG4785  73 AQLYYERGVAYDSLGDYDLAIADFDQA---LELDPDLAE------------AYNNRGLAYLLLGDYDAALEDFDRALELD 137

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 1020307  348 SANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDR 406
Cdd:COG4785 138 PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKALAL 196
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
247-438 1.01e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 64.64  E-value: 1.01e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  247 LKSFEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIvswLEMEYGLSEkeskasesfllaAFLNLAMC 326
Cdd:COG0457  55 LGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKA---LELDPDDAE------------ALYNLGLA 119

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  327 YLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDR 406
Cdd:COG0457 120 LLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLAL 199

                       170       180       190
                ....*....|....*....|....*....|..
gi 1020307  407 RVYANMFKKFAERDAKEEASKAGSKKAVEGAA 438
Cdd:COG0457 200 LLALEQALRKKLAILTLAALAELLLLALALLL 231
PRK11570 PRK11570
peptidyl-prolyl cis-trans isomerase; Provisional
 47-136 1.15e-11

peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 183207 [Multi-domain]  Cd Length: 206  Bit Score: 64.05  E-value: 1.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    47 PMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLgqGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNA 126
Cdd:PRK11570 117 PARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPV--NGVIPGWIEALTLMPVGSKWELTIPHELAYGERGAGASIPPFS 194

                         90
                 ....*....|
gi 1020307   127 TLFFEIELLD 136
Cdd:PRK11570 195 TLVFEVELLE 204
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 275-389 2.26e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.18  E-value: 2.26e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  275 GTVYFKGGKYTQAVIQYRKIVSwlemeygLSEKESkasesfllAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGL 354
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALR-------LDPDNA--------DALLDLAEALLAAGDTEEAEELLERALALDPDNPEAL 88

                        90       100       110
                ....*....|....*....|....*....|....*
gi 1020307  355 YRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARL 389
Cdd:COG4235  89 YLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 319-403 3.70e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.40  E-value: 3.70e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  319 AFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKA 398
Cdd:COG4235  19 GWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQ 98


                ....*
gi 1020307  399 KEHNE 403
Cdd:COG4235  99 GDYAE 103
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 275-406 1.05e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.86  E-value: 1.05e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  275 GTVYFKGGKYTQAVIQYRKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGL 354
Cdd:COG3914 119 GNLLLALGRLEEALAALRRA---LALNPDFAE------------AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEAL 183

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 1020307  355 YRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDR 406
Cdd:COG3914 184 NNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDR 235
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 315-403 2.43e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.82  E-value: 2.43e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  315 FLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMC 394
Cdd:COG5010  52 KAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAAL 131


                ....*....
gi 1020307  395 QRKAKEHNE 403
Cdd:COG5010 132 LLSLGQDDE 140
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 250-403 3.08e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.90  E-value: 3.08e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  250 FEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIvswlemeyglsEKESKASESFLLaaflNLAMCYLK 329
Cdd:COG2956  92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERL-----------LKLGPENAHAYC----ELAELYLE 156

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1020307  330 LREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG2956 157 QGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 267-403 1.22e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.35  E-value: 1.22e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  267 QAAIVKEKGTVYFKGGKYTQAVIQYRKIVswlemeyglseKESKASEsfllAAFLNLAMCYLKLREYNKAVECCDKALGL 346
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKAL-----------ELDPDNP----EAFALLGEILLQLGDLDEAIVLLHEALEL 67

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 1020307  347 DSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG4783  68 DPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDE 124
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 274-384 1.43e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.35  E-value: 1.43e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  274 KGTVYFKGGKYTQAVIQYRKIVSwlemeygLSEKESkasesfllAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKG 353
Cdd:COG4783  44 LGEILLQLGDLDEAIVLLHEALE-------LDPDEP--------EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEA 108

                        90       100       110
                ....*....|....*....|....*....|.
gi 1020307  354 LYRRGEAQLLMNDFESAKGDFEKVLAVNPQN 384
Cdd:COG4783 109 YLRLARAYRALGRPDEAIAALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 263-382 1.93e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.12  E-value: 1.93e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  263 EKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSwlemeygLSEKESkasesfllAAFLNLAMCYLKLREYNKAVECCDK 342
Cdd:COG5010  49 KLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ-------LDPNNP--------ELYYNLALLYSRSGDKDEAKEYYEK 113

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 1020307  343 ALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNP 382
Cdd:COG5010 114 ALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
SlpA COG1047
Peptidyl-prolyl cis-trans isomerase, FKBP type [Posttranslational modification, protein ...
 50-144 3.48e-09

Peptidyl-prolyl cis-trans isomerase, FKBP type [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440668 [Multi-domain]  Cd Length: 138  Bit Score: 55.11  E-value: 3.48e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307   50 GDKVYVHYKGMLSDGKKFDSSHDRkKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGsaghlqkiPSNATLF 129
Cdd:COG1047   4 GDVVTLHYTLKLEDGEVFDSTFEG-EPLEFLHGAGQLIPGLEEALEGMEVGDKKTVTLPPEEAYG--------ERDPELV 74

                        90
                ....*....|....*
gi 1020307  130 FEIELLDFKGEDLFE 144
Cdd:COG1047  75 QTVPREQFPEDEELE 89
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 267-403 3.55e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.85  E-value: 3.55e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  267 QAAIVKEKGTVYFKGGKYTQAVIQYRKIVswlemeyglsekeskASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGL 346
Cdd:COG3914  77 LAALLELAALLLQALGRYEEALALYRRAL---------------ALNPDNAEALFNLGNLLLALGRLEEALAALRRALAL 141

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 1020307  347 DSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG3914 142 NPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEE 198
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
316-389 1.85e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.92  E-value: 1.85e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1020307  316 LLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARL 389
Cdd:COG4785  72 LAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYL 145
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 273-403 5.36e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 5.36e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  273 EKGTVYFKGGKYTQAVIQYRKIVswlemeyglsEKESKASEsfllaAFLNLAMCYLKLREYNKAVECCDKALGLDSANEK 352
Cdd:COG2956  13 FKGLNYLLNGQPDKAIDLLEEAL----------ELDPETVE-----AHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAE 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 1020307  353 GLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG2956  78 ALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEK 128
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
326-403 7.88e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.78  E-value: 7.88e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1020307  326 CYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKgDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDE 77
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 230-397 9.13e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 54.60  E-value: 9.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    230 KPKF-GIDPNAELMYEVTLKSFEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEY-GLSEK 307
Cdd:TIGR00990 274 KPRPaGLEDSNELDEETGNGQLQLGLKSPESKADESYEEAARAFEKALDLGKLGEKEAIALNLRGTFKCLKGKHlEALAD 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    308 ESKASESF--LLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNR 385
Cdd:TIGR00990 354 LSKSIELDprVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFI 433

                         170
                  ....*....|..
gi 1020307    386 AARLQISMCQRK 397
Cdd:TIGR00990 434 FSHIQLGVTQYK 445
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
277-386 1.39e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.40  E-value: 1.39e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  277 VYFKGGKYTQAVIQYRKIVSwLEMEYGlsekeskasesfllAAFLNLAMCYLKLREYNKAVECcDKALGLDSANEKGLYR 356
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALE-LDPDNA--------------DALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLN 64

                        90       100       110
                ....*....|....*....|....*....|
gi 1020307  357 RGEAQLLMNDFESAKGDFEKVLAVNPQNRA 386
Cdd:COG3063  65 LAELLLELGDYDEALAYLERALELDPSALR 94
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 278-389 2.27e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 49.22  E-value: 2.27e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  278 YFKGGKYTQAVIQYRKIVSwlemeyglsekesKASESFLLA-AFLNLAMCYLKLREYNKAVECCDKALGLDSANEK---G 353
Cdd:COG1729   3 LLKAGDYDEAIAAFKAFLK-------------RYPNSPLAPdALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdA 69

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 1020307  354 LYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARL 389
Cdd:COG1729  70 LLKLGLSYLELGDYDKARATLEELIKKYPDSEAAKE 105
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 275-393 1.21e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 1.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    275 GTVYFKGGKYTQAVIQYRKIVswlemeyglsekesKASESFLLAAFLnLAMCYLKLREYNKAVECCDKALGLDSANEKGL 354
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQIL--------------KYAPNSHQARRL-LASIQLRLGRVDEAIATLSPALGLDPDDPAAL 366

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1020307    355 YRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISM 393
Cdd:TIGR02917 367 SLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGI 405
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 275-400 2.52e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 2.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    275 GTVYFKGGKYTQAVIQYRKIVSwlemeYGLSEKeskasesfllAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGL 354
Cdd:TIGR02917  63 GKIYLALGDYAAAEKELRKALS-----LGYPKN----------QVLPLLARAYLLQGKFQQVLDELPGKTLLDDEGAAEL 127

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1020307    355 YR-RGEAQLLMNDFESAKGDFEKVLAVNPQNRAARL---QISMCQRKAKE 400
Cdd:TIGR02917 128 LAlRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLglaQLALAENRFDE 177
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 319-350 3.66e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 43.20  E-value: 3.66e-06
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1020307     319 AFLNLAMCYLKLREYNKAVECCDKALGLDSAN 350
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
319-347 5.10e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.79  E-value: 5.10e-06
                          10        20
                  ....*....|....*....|....*....
gi 1020307    319 AFLNLAMCYLKLREYNKAVECCDKALGLD 347
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELN 31
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 335-403 1.28e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.61  E-value: 1.28e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1020307  335 KAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEE 69
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 315-403 1.44e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.65  E-value: 1.44e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  315 FLLAAF----LNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQ 390
Cdd:COG2956   2 LLPVAAalgwYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLE 81

                        90
                ....*....|...
gi 1020307  391 ISMCQRKAKEHNE 403
Cdd:COG2956  82 LAQDYLKAGLLDR 94
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 263-423 3.61e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 46.13  E-value: 3.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    263 EKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVswlemeyglsekESKASESFllaaFLNLAMCYLKLREYNKAVECCDK 342
Cdd:TIGR00990 122 ERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAI------------ECKPDPVY----YSNRAACHNALGDWEKVVEDTTA 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    343 ALGLDSANEKGLYRRGEAQLLMNDFESAKGDFeKVLAVNPQNRaarlqismcqrkakehNERDRRVYANMFKKFAERDAK 422
Cdd:TIGR00990 186 ALELDPDYSKALNRRANAYDGLGKYADALLDL-TASCIIDGFR----------------NEQSAQAVERLLKKFAESKAK 248


                  .
gi 1020307    423 E 423
Cdd:TIGR00990 249 E 249
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 295-409 7.45e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 7.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    295 VSWLEMEYGLSEKEskasesflLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDF 374
Cdd:TIGR02917 553 VAWLEKAAELNPQE--------IEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1020307    375 EKVLAVNPQNRAARLQISMCQRKAKEhNERDRRVY 409
Cdd:TIGR02917 625 KKLLALQPDSALALLLLADAYAVMKN-YAKAITSL 658
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 305-403 1.86e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 43.62  E-value: 1.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307   305 SEKESKASESFL-----LAA----------------FLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Cdd:PLN03088   3 KDLEDKAKEAFVdddfaLAVdlytqaidldpnnaelYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMK 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 1020307   364 MNDFESAKGDFEKVLAVNPQN-RAARLqISMCQRKAKEHNE 403
Cdd:PLN03088  83 LEEYQTAKAALEKGASLAPGDsRFTKL-IKECDEKIAEEEK 122
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
292-391 3.69e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 42.18  E-value: 3.69e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  292 RKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYNKAVECCDKAL-GLDSANEKGLYRRGEAQLLMNDFESA 370
Cdd:COG4700  64 RAARNALDPGRELRELEKALEFADTVQNRVRLADALLELGRYDEAIELYEEALtGIFADDPHILLGLAQALFELGRYAEA 143

                        90       100
                ....*....|....*....|.
gi 1020307  371 KGDFEKVLAVNPQNRAARLQI 391
Cdd:COG4700 144 LETLEKLIAKNPDFKSSDAHL 164
TPR_1 pfam00515
Tetratricopeptide repeat;
352-384 5.09e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 5.09e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1020307    352 KGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQN 384
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_12 pfam13424
Tetratricopeptide repeat;
315-383 5.48e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.52  E-value: 5.48e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1020307    315 FLLAAFLNLAMCYLKLREYNKAVECCDKAL-------GLDSANEKGLYRR-GEAQLLMNDFESAKGDFEKVLAVNPQ 383
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALeiarrllGPDHPLTATTLLNlGRLYLELGRYEEALELLERALALAEK 77
TPR_9 pfam13371
Tetratricopeptide repeat;
326-389 6.55e-04

Tetratricopeptide repeat;


Pssm-ID: 463860 [Multi-domain]  Cd Length: 73  Bit Score: 38.35  E-value: 6.55e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1020307    326 CYLKLREYNKAVECCDKALGLDSaNEKGLYR-RGEAQLLMNDFESAKGDFEKVLAVNPQNRAARL 389
Cdd:pfam13371   4 IYLREEDWERALAVVERLLLLAP-DDPEERRdRGLLYAQLGCFQAALEDLEAYLELAPDAPDAEA 67
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 318-382 8.50e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.07  E-value: 8.50e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1020307  318 AAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNP 382
Cdd:cd24142   1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 352-384 1.65e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.89  E-value: 1.65e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1020307     352 KGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQN 384
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 344-419 1.77e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.10  E-value: 1.77e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1020307  344 LGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHnERDRRVYANMFKKFAER 419
Cdd:COG2956   1 LLLPVAAALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEY-DRAIRIHQKLLERDPDR 75
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
275-412 2.83e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.48  E-value: 2.83e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  275 GTVYFKGGKYTQAVIQYRKIVSwlemeyGLSEKEskasesflLAAFLNLAMCYLKLREYNKAVECCDKALGLDSAnekgl 354
Cdd:COG4700  96 ADALLELGRYDEAIELYEEALT------GIFADD--------PHILLGLAQALFELGRYAEALETLEKLIAKNPD----- 156

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1020307  355 YRRGEAQLL-------MNDFESAKGDFEKVLAVNPqNRAARLQISMCQRKAKEHNERdRRVYANM 412
Cdd:COG4700 157 FKSSDAHLLyaraleaLGDLEAAEAELEALARRYS-GPEARYRYAKFLARQGRTAEA-KELLEEI 219
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 281-389 3.03e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    281 GGKYTQAVIQYRKIVSWLEMEYGLSEKESKASESFLLAAFLN-------LAMCYLKL--REYNKAVECCDKALGLDSANE 351
Cdd:TIGR02917 114 PGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDprslyakLGLAQLALaeNRFDEARALIDEVLTADPGNV 193

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1020307    352 KGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARL 389
Cdd:TIGR02917 194 DALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLL 231
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 247-425 4.06e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.68  E-value: 4.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    247 LKSFEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVswlEMEYGLSEKESKASESFL--------LA 318
Cdd:TIGR02917 376 LGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAA---QLDPELGRADLLLILSYLrsgqfdkaLA 452

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    319 A--------------FLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQN 384
Cdd:TIGR02917 453 AakklekkqpdnaslHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKN 532

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1020307    385 RAARLQISmcQRKAKEHNERDrrvYANMFKKFAERDAKEEA 425
Cdd:TIGR02917 533 LRAILALA--GLYLRTGNEEE---AVAWLEKAAELNPQEIE 568
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
344-403 4.80e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.45  E-value: 4.80e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307  344 LGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNE 403
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEE 60
TPR_8 pfam13181
Tetratricopeptide repeat;
319-349 5.08e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 34.68  E-value: 5.08e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1020307    319 AFLNLAMCYLKLREYNKAVECCDKALGLDSA 349
Cdd:pfam13181   3 AYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 319-347 6.19e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 34.42  E-value: 6.19e-03
                          10        20
                  ....*....|....*....|....*....
gi 1020307    319 AFLNLAMCYLKLREYNKAVECCDKALGLD 347
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELD 31
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 301-395 7.29e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 7.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1020307    301 EYGLSEKESKASESFL----------LAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESA 370
Cdd:TIGR02917 575 QYYLGKGQLKKALAILneaadaapdsPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKA 654

                          90       100
                  ....*....|....*....|....*
gi 1020307    371 KGDFEKVLAVNPQNRaaRLQISMCQ 395
Cdd:TIGR02917 655 ITSLKRALELKPDNT--EAQIGLAQ 677
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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