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Conserved domains on  [gi|624725|gb|AAA61251|]
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UDP-glucuronosyltransferase [Homo sapiens]

Protein Classification

UDP-glycosyltransferase family protein( domain architecture ID 11989770)

UDP-glycosyltransferase family protein similar to UDP-glucuronosyltransferase (UDPGT), which is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds

EC:  2.4.-.-
Gene Ontology:  GO:0008194|GO:0006486
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
27-522 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


:

Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 853.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725      27 DKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKEYK--YYTRKIYPVPYDQEELKNRYQSFGNNHFAERSF 104
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGPGKpsNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     105 LTaPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFS- 183
Cdd:pfam00201  81 GT-VWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     184 RSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEKLASAVLKRDVDII-TLSEVSVWLLRYDFVLEY 262
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPeLMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     263 PRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKNPQTVLWRYTGTRPSN 342
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     343 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 422
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     423 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 502
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 624725     503 ITFKCCPYGYPKCLGKKGRV 522
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
27-522 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 853.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725      27 DKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKEYK--YYTRKIYPVPYDQEELKNRYQSFGNNHFAERSF 104
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGPGKpsNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     105 LTaPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFS- 183
Cdd:pfam00201  81 GT-VWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     184 RSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEKLASAVLKRDVDII-TLSEVSVWLLRYDFVLEY 262
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPeLMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     263 PRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKNPQTVLWRYTGTRPSN 342
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     343 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 422
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     423 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 502
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 624725     503 ITFKCCPYGYPKCLGKKGRV 522
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 29-444 2.83e-76

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 246.31  E-value: 2.83e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    29 LLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLllkeykyytrkiypvPYDQEELKNRYQSFGNNHFAERSFLTAP 108
Cdd:cd03784   4 LFVPFPGQGHVNPMLPLAKALAARGHEVTVATPPFNF---------------ADLVEAAGLTFVPVGDDPDELELDSETN 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   109 QTEYRNNMIVIGLYFINCQSLlqdRDTLNFFKES-KFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPD 187
Cdd:cd03784  69 LGPDSLLELLRRLLKAADELL---DDLLAALRSSwKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSAYLHPFGV 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   188 PVSYIPrcytKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEKLasavLKRDVDIItlseVSVWllrydFVLEYPRPVM 267
Cdd:cd03784 146 LNLLLS----SLLEPELFLDPLLEVLDRLRERLGLPPFSLVLLLL----RLVPPLYV----IGPT-----FPSLPPDRPR 208

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   268 PNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKNPQTVLWRYTGTRPS---NLA 344
Cdd:cd03784 209 LPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRLP 288

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   345 NNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENA 424
Cdd:cd03784 289 DNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAKA 368

                       410       420
                ....*....|....*....|
gi 624725   425 LKAVINDKSYKENIMRLSSL 444
Cdd:cd03784 369 VREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 15-505 8.54e-46

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 167.83  E-value: 8.54e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     15 VFFLALWGMVVGDKLLVV-PQDG-SHWLSMKDIVEVLSDRGHEIVVVVPevnlllKEYKYYTRKIYP--------VPYDQ 84
Cdd:PHA03392   9 LLLLLLLSGVRAARILAVfPTPAySHHSVFKVYVEALAERGHNVTVIKP------TLRVYYASHLCGniteidasLSVEY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     85 -EELKNRYQSFGNNHF-AERSFLTApqTEYRN--NMIVIGLYFINCQSLLQdrdtlnfFKESKFDALFTDPalpcgvila 160
Cdd:PHA03392  83 fKKLVKSSAVFRKRGVvADSSTVTA--DNYMGlvRMISDQFDLPNVKNLIA-------NKNNKFDLLVTEA--------- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    161 eYLGLPSVYlfrgfpcslEHTFSRSP-----------------DPVSYIPRCY-----TKFSDHMTFsQRVANFLVnllE 218
Cdd:PHA03392 145 -FLDYPLVF---------SHLFGDAPviqissgyglaenfetmGAVSRHPVYYpnlwrSKFGNLNVW-ETINEIYT---E 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    219 PYLfYCLFSKYEKLASAVLKRD--VDIITLSEV--SVWLLrydFVLEYP-----RPVMPNMVFIGGI--NCKKRKDLSQE 287
Cdd:PHA03392 211 LRL-YNEFSLLADEQNKLLKQQfgPDTPTIRELrnRVQLL---FVNVHPvfdnnRPVPPSVQYLGGLhlHKKPPQPLDDY 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    288 FEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKNPQTVLWRYTGT-RPSNLANNTILVKWLPQNDLLG 360
Cdd:PHA03392 287 LEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYNVLWKYDGEvEAINLPANVLTQKWFPQRAVLK 361

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    361 HPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 440
Cdd:PHA03392 362 HKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKE 441

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 624725    441 LSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsldVIGFLLAVVLTVAFITF 505
Cdd:PHA03392 442 LRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY----FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
260-442 1.98e-31

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 122.27  E-value: 1.98e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   260 LEYPRPVMP-NMVFIGGInckkRKDLSQEFEAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKNPQTVLWRYTGT 338
Cdd:COG1819  85 LEYPRPPDPaNVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGL 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   339 RPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE 415
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237

                       170       180
                ....*....|....*....|....*..
gi 624725   416 MTSEDLENALKAVINDKSYKENIMRLS 442
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 45-441 4.27e-23

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 101.30  E-value: 4.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725      45 IVEVLSDRGHEIVVVVPEvnlLLKEYKYYTR---KIYPVPYDQEELKNryqsfgnnHFAERSFLTAPQTEYRNNMIVIgl 121
Cdd:TIGR01426  15 VVEELVARGHRVTYATTE---EFAERVEAAGaefVLYGSALPPPDNPP--------ENTEEEPIDIIEKLLDEAEDVL-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     122 yfincQSLLQDrdtlnfFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHtfsrsPDPVSYIPRCYTKFSD 201
Cdd:TIGR01426  82 -----PQLEEA------YKGDRPDLIVYDIASWTGRLLARKWDVPVISSFPTFAANEEF-----EEMVSPAGEGSAEEGA 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     202 HMTFSQRvanflvnllepylfyclfsKYEKLASAVLKR-DVDIITLSEVSVwlLRYDFVLEY-PRPVMPN-------MVF 272
Cdd:TIGR01426 146 IAERGLA-------------------EYVARLSALLEEhGITTPPVEFLAA--PRRDLNLVYtPKAFQPAgetfddsFTF 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     273 IGGINCKKRKDLSqefeAYINASGeHGIVVFSLGSMVSEIPEKKAMAIaDALGKNP-QTVLWRYTGTRPSNLAN---NTI 348
Cdd:TIGR01426 205 VGPCIGDRKEDGS----WERPGDG-RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNVE 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     349 LVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAV 428
Cdd:TIGR01426 279 VRQWVPQLEILKK--ADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAV 356

                         410
                  ....*....|...
gi 624725     429 INDKSYKENIMRL 441
Cdd:TIGR01426 357 LSDPRYAERLRKM 369
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
27-522 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 853.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725      27 DKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKEYK--YYTRKIYPVPYDQEELKNRYQSFGNNHFAERSF 104
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGPGKpsNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     105 LTaPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFS- 183
Cdd:pfam00201  81 GT-VWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     184 RSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEKLASAVLKRDVDII-TLSEVSVWLLRYDFVLEY 262
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPeLMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     263 PRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKNPQTVLWRYTGTRPSN 342
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     343 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 422
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     423 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 502
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 624725     503 ITFKCCPYGYPKCLGKKGRV 522
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 29-444 2.83e-76

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 246.31  E-value: 2.83e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    29 LLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLllkeykyytrkiypvPYDQEELKNRYQSFGNNHFAERSFLTAP 108
Cdd:cd03784   4 LFVPFPGQGHVNPMLPLAKALAARGHEVTVATPPFNF---------------ADLVEAAGLTFVPVGDDPDELELDSETN 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   109 QTEYRNNMIVIGLYFINCQSLlqdRDTLNFFKES-KFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPD 187
Cdd:cd03784  69 LGPDSLLELLRRLLKAADELL---DDLLAALRSSwKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSAYLHPFGV 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   188 PVSYIPrcytKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEKLasavLKRDVDIItlseVSVWllrydFVLEYPRPVM 267
Cdd:cd03784 146 LNLLLS----SLLEPELFLDPLLEVLDRLRERLGLPPFSLVLLLL----RLVPPLYV----IGPT-----FPSLPPDRPR 208

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   268 PNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKNPQTVLWRYTGTRPS---NLA 344
Cdd:cd03784 209 LPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRLP 288

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   345 NNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENA 424
Cdd:cd03784 289 DNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAKA 368

                       410       420
                ....*....|....*....|
gi 624725   425 LKAVINDKSYKENIMRLSSL 444
Cdd:cd03784 369 VREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 15-505 8.54e-46

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 167.83  E-value: 8.54e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     15 VFFLALWGMVVGDKLLVV-PQDG-SHWLSMKDIVEVLSDRGHEIVVVVPevnlllKEYKYYTRKIYP--------VPYDQ 84
Cdd:PHA03392   9 LLLLLLLSGVRAARILAVfPTPAySHHSVFKVYVEALAERGHNVTVIKP------TLRVYYASHLCGniteidasLSVEY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     85 -EELKNRYQSFGNNHF-AERSFLTApqTEYRN--NMIVIGLYFINCQSLLQdrdtlnfFKESKFDALFTDPalpcgvila 160
Cdd:PHA03392  83 fKKLVKSSAVFRKRGVvADSSTVTA--DNYMGlvRMISDQFDLPNVKNLIA-------NKNNKFDLLVTEA--------- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    161 eYLGLPSVYlfrgfpcslEHTFSRSP-----------------DPVSYIPRCY-----TKFSDHMTFsQRVANFLVnllE 218
Cdd:PHA03392 145 -FLDYPLVF---------SHLFGDAPviqissgyglaenfetmGAVSRHPVYYpnlwrSKFGNLNVW-ETINEIYT---E 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    219 PYLfYCLFSKYEKLASAVLKRD--VDIITLSEV--SVWLLrydFVLEYP-----RPVMPNMVFIGGI--NCKKRKDLSQE 287
Cdd:PHA03392 211 LRL-YNEFSLLADEQNKLLKQQfgPDTPTIRELrnRVQLL---FVNVHPvfdnnRPVPPSVQYLGGLhlHKKPPQPLDDY 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    288 FEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKNPQTVLWRYTGT-RPSNLANNTILVKWLPQNDLLG 360
Cdd:PHA03392 287 LEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYNVLWKYDGEvEAINLPANVLTQKWFPQRAVLK 361

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    361 HPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 440
Cdd:PHA03392 362 HKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKE 441

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 624725    441 LSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsldVIGFLLAVVLTVAFITF 505
Cdd:PHA03392 442 LRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY----FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
260-442 1.98e-31

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 122.27  E-value: 1.98e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   260 LEYPRPVMP-NMVFIGGInckkRKDLSQEFEAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKNPQTVLWRYTGT 338
Cdd:COG1819  85 LEYPRPPDPaNVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGL 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   339 RPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE 415
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237

                       170       180
                ....*....|....*....|....*..
gi 624725   416 MTSEDLENALKAVINDKSYKENIMRLS 442
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 45-441 4.27e-23

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 101.30  E-value: 4.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725      45 IVEVLSDRGHEIVVVVPEvnlLLKEYKYYTR---KIYPVPYDQEELKNryqsfgnnHFAERSFLTAPQTEYRNNMIVIgl 121
Cdd:TIGR01426  15 VVEELVARGHRVTYATTE---EFAERVEAAGaefVLYGSALPPPDNPP--------ENTEEEPIDIIEKLLDEAEDVL-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     122 yfincQSLLQDrdtlnfFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHtfsrsPDPVSYIPRCYTKFSD 201
Cdd:TIGR01426  82 -----PQLEEA------YKGDRPDLIVYDIASWTGRLLARKWDVPVISSFPTFAANEEF-----EEMVSPAGEGSAEEGA 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     202 HMTFSQRvanflvnllepylfyclfsKYEKLASAVLKR-DVDIITLSEVSVwlLRYDFVLEY-PRPVMPN-------MVF 272
Cdd:TIGR01426 146 IAERGLA-------------------EYVARLSALLEEhGITTPPVEFLAA--PRRDLNLVYtPKAFQPAgetfddsFTF 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     273 IGGINCKKRKDLSqefeAYINASGeHGIVVFSLGSMVSEIPEKKAMAIaDALGKNP-QTVLWRYTGTRPSNLAN---NTI 348
Cdd:TIGR01426 205 VGPCIGDRKEDGS----WERPGDG-RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNVE 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     349 LVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAV 428
Cdd:TIGR01426 279 VRQWVPQLEILKK--ADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAV 356

                         410
                  ....*....|...
gi 624725     429 INDKSYKENIMRL 441
Cdd:TIGR01426 357 LSDPRYAERLRKM 369
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 147-433 1.87e-14

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 75.48  E-value: 1.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    147 LFTDPALPCGVILAEYLGLPSVYLFRGFPcSLEHTfsrspDPVSYIPRCYTKFSDHMTFsQRVANFLVNLLEPYLFYCLF 226
Cdd:PLN02152 133 LWIQPAFVFDIYYNYSTGNNSVFEFPNLP-SLEIR-----DLPSFLSPSNTNKAAQAVY-QELMEFLKEESNPKILVNTF 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    227 SKYEKLASAVLKrDVDIITLSevsvwllrydfvleyprPVMPNMVFIGGINCKK--RKDLSQEFEAYINASGEHGIVVFS 304
Cdd:PLN02152 206 DSLEPEFLTAIP-NIEMVAVG-----------------PLLPAEIFTGSESGKDlsVRDQSSSYTLWLDSKTESSVIYVS 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    305 LGSMVsEIPEKKAMAIADAL--GKNP-------------------QTVLWRYTGTRpSNLANNTILVKWLPQNDLLGHPM 363
Cdd:PLN02152 268 FGTMV-ELSKKQIEELARALieGKRPflwvitdklnreakiegeeETEIEKIAGFR-HELEEVGMIVSWCSQIEVLRHRA 345

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 624725    364 TRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME---TKGAGVTLNVLEMTSE-DLENALKAVINDKS 433
Cdd:PLN02152 346 VGCFVTHCGWSSSLESLVLGVPVVAFPMWSDQPANAKLLEeiwKTGVRVRENSEGLVERgEIRRCLEAVMEEKS 419
PLN02410 PLN02410
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 291-403 6.36e-13

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 178032 [Multi-domain]  Cd Length: 451  Bit Score: 70.84  E-value: 6.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    291 YINASGEHGIVVFSLGSM-VSEIPEkkAMAIADALGKNPQTVLWRytgTRPSNLANNT-----------------ILVKW 352
Cdd:PLN02410 257 WLNKQKKNSVIFVSLGSLaLMEINE--VMETASGLDSSNQQFLWV---IRPGSVRGSEwieslpkefskiisgrgYIVKW 331

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 624725    353 LPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME 403
Cdd:PLN02410 332 APQKEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLE 382
PLN02210 PLN02210
UDP-glucosyl transferase
 291-428 8.56e-10

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 60.82  E-value: 8.56e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    291 YINASGEHGIVVFSLGSMVSEIpEKKAMAIADALGKNPQTVLWRytgTRPSNLANNT------------ILVKWLPQNDL 358
Cdd:PLN02210 262 WLDKQARSSVVYISFGSMLESL-ENQVETIAKALKNRGVPFLWV---IRPKEKAQNVqvlqemvkegqgVVLEWSPQEKI 337

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 624725    359 LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVL----EMTSEDLENALKAV 428
Cdd:PLN02210 338 LSHMAISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPIDARLLvDVFGIGVRMRNDavdgELKVEEVERCIEAV 412
PLN03015 PLN03015
UDP-glucosyl transferase
 291-419 2.37e-09

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 59.71  E-value: 2.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    291 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKNPQTVLW------RYTG-----------TRPSNLANNT-----I 348
Cdd:PLN03015 260 WLDKQGERSVVYVCLGSG-GTLTFEQTVELAWGLELSGQRFVWvlrrpaSYLGasssdddqvsaSLPEGFLDRTrgvglV 338

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 624725    349 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKrMETKGAGVTLNVLEMTSE 419
Cdd:PLN03015 339 VTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNAT-LLTEEIGVAVRTSELPSE 408
PLN02555 PLN02555
limonoid glucosyltransferase
 349-440 6.17e-09

limonoid glucosyltransferase


Pssm-ID: 178170 [Multi-domain]  Cd Length: 480  Bit Score: 58.27  E-value: 6.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    349 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL------NVLEMTSEDL 421
Cdd:PLN02555 341 IVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYLvDVFKTGVRLcrgeaeNKLITREEVA 420

                         90       100
                 ....*....|....*....|.
gi 624725    422 ENALKAVINDKS--YKENIMR 440
Cdd:PLN02555 421 ECLLEATVGEKAaeLKQNALK 441
PLN03004 PLN03004
UDP-glycosyltransferase
 268-443 6.65e-09

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 58.16  E-value: 6.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    268 PNMVFIGGINCKKRKDLSQEFEA-----YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKNPQTVLWryTGTRPSN 342
Cdd:PLN03004 235 RNIYPIGPLIVNGRIEDRNDNKAvsclnWLDSQPEKSVVFLCFGSL-GLFSKEQVIEIAVGLEKSGQRFLW--VVRNPPE 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    343 LANNTILVK--------------------WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 402
Cdd:PLN03004 312 LEKTELDLKsllpegflsrtedkgmvvksWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMI 391

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 624725    403 -ETKGAGVTLNVLE---MTSEDLENALKAVINDKSYKENIMRLSS 443
Cdd:PLN03004 392 vDEIKIAISMNESEtgfVSSTEVEKRVQEIIGECPVRERTMAMKN 436
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 265-444 7.39e-09

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 58.12  E-value: 7.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    265 PVMPNMVFIGGINCKKRKDLSQeFEA--------YINASGEHGIVVFSLGSMV---SEIPEKKAMAIADAlgknpqTVLW 333
Cdd:PLN02173 224 PTVPSMYLDQQIKSDNDYDLNL-FDLkeaalctdWLDKRPQGSVVYIAFGSMAklsSEQMEEIASAISNF------SYLW 296

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    334 RYTGTRPSNL---------ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME- 403
Cdd:PLN02173 297 VVRASEESKLppgfletvdKDKSLVLKWSPQLQVLSNKAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQd 376

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 624725    404 TKGAGVTLNVLEMTS----EDLENALKAVIN---DKSYKENIMRLSSL 444
Cdd:PLN02173 377 VWKVGVRVKAEKESGiakrEEIEFSIKEVMEgekSKEMKENAGKWRDL 424
PLN00164 PLN00164
glucosyltransferase; Provisional
 301-399 9.15e-09

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 57.76  E-value: 9.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    301 VVF-SLGSMVSeIPEKKAMAIADALGKNPQTVLWRYTGTRP--------SNLA-----------NNTILV--KWLPQNDL 358
Cdd:PLN00164 274 VVFlCFGSMGF-FDAPQVREIAAGLERSGHRFLWVLRGPPAagsrhptdADLDellpegflertKGRGLVwpTWAPQKEI 352

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 624725    359 LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 399
Cdd:PLN00164 353 LAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNA 393
PLN02534 PLN02534
UDP-glycosyltransferase
 348-413 1.40e-08

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 57.18  E-value: 1.40e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 624725    348 ILVK-WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNV 413
Cdd:PLN02534 346 LLIKgWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQFLNEKLIvEVLRIGVRVGV 413
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 352-399 2.45e-08

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 56.53  E-value: 2.45e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 624725    352 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 399
Cdd:PLN02992 345 WAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNA 392
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 141-400 2.34e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 53.09  E-value: 2.34e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    141 ESKFDALFTDPALPCGVILAEYLGLP-------SVYLFrgfpcSLEHTFSRSP-------DP-------VSYIPRCY-TK 198
Cdd:PLN02448 106 EPPVTAIVADTYLFWAVGVGNRRNIPvaslwtmSATFF-----SVFYHFDLLPqnghfpvELsesgeerVDYIPGLSsTR 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    199 FSDHMTFSQRVANFLVNL-LEPYLF-----YCLF-SKYEKLASAV--LKRDVDIITlsevsvwllrydfvleYP-RPVMP 268
Cdd:PLN02448 181 LSDLPPIFHGNSRRVLKRiLEAFSWvpkaqYLLFtSFYELEAQAIdaLKSKFPFPV----------------YPiGPSIP 244

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    269 NMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKNPQTVLW---RYTGTRPSNLAN 345
Cdd:PLN02448 245 YMELKDNSSSSNNEDNEPDYFQWLDSQPEGSVLYVSLGSFLS-VSSAQMDEIAAGLRDSGVRFLWvarGEASRLKEICGD 323

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 624725    346 NTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAK 400
Cdd:PLN02448 324 MGLVVPWCDQLKVLCHSSVGGFWTHCGWNSTLEAVFAGVPMLTFPLFWDQPLNSK 378
PLN02562 PLN02562
UDP-glycosyltransferase
 300-441 3.69e-07

UDP-glycosyltransferase


Pssm-ID: 215305  Cd Length: 448  Bit Score: 52.58  E-value: 3.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    300 IVVFSLGSMVSEIPEKKAMAIADALGKNPQTVLWRYT-----GTRPS---NLANNTILVKWLPQNDLLGHPMTRAFITHA 371
Cdd:PLN02562 275 VIYISFGSWVSPIGESNVRTLALALEASGRPFIWVLNpvwreGLPPGyveRVSKQGKVVSWAPQLEVLKHQAVGCYLTHC 354

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 624725    372 GSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNvlEMTSEDLENALKAVINDKSYKENIMRL 441
Cdd:PLN02562 355 GWNSTMEAIQCQKRLLCYPVAGDQFVNCAYIvDVWKIGVRIS--GFGQKEVEEGLRKVMEDSGMGERLMKL 423
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 301-442 5.26e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 52.10  E-value: 5.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    301 VVF-SLGSMvSEIPEKKAMAIADALGKNPQTVLW-------RYTGTRPSNLAN-NTIL--------------VKWLPQND 357
Cdd:PLN02554 276 VVFlCFGSM-GGFSEEQAREIAIALERSGHRFLWslrraspNIMKEPPGEFTNlEEILpegfldrtkdigkvIGWAPQVA 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    358 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL-----------NVLEMTSEDLENAL 425
Cdd:PLN02554 355 VLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEMvEELGLAVEIrkywrgdllagEMETVTAEEIERGI 434

                        170
                 ....*....|....*...
gi 624725    426 KAVI-NDKSYKENIMRLS 442
Cdd:PLN02554 435 RCLMeQDSDVRKRVKEMS 452
PLN02167 PLN02167
UDP-glycosyltransferase family protein
 262-402 3.16e-06

UDP-glycosyltransferase family protein


Pssm-ID: 215112 [Multi-domain]  Cd Length: 475  Bit Score: 49.80  E-value: 3.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    262 YPrPVMPnmvfIGGINCKKRK-----DLSQ--EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKNPQTVLW- 333
Cdd:PLN02167 242 YP-PVYP----VGPILSLKDRtspnlDSSDrdRIMRWLDDQPESSVVFLCFGSLGS-LPAPQIKEIAQALELVGCRFLWs 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    334 -RYTGTR--------PSNLANNT----ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAK 400
Cdd:PLN02167 316 iRTNPAEyaspyeplPEGFMDRVmgrgLVCGWAPQVEILAHKAIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQLNAF 395


                 ..
gi 624725    401 RM 402
Cdd:PLN02167 396 TM 397
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 290-399 3.89e-06

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 49.48  E-value: 3.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    290 AYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKNPQTVLW------RYTGTR---PSNLANNT-----ILVKWLPQ 355
Cdd:PLN02863 275 TWLDTCEDHKVVYVCFGSQVV-LTKEQMEALASGLEKSGVHFIWcvkepvNEESDYsniPSGFEDRVagrglVIRGWAPQ 353

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 624725    356 NDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 399
Cdd:PLN02863 354 VAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQFVNA 397
PLN02207 PLN02207
UDP-glycosyltransferase
 282-402 6.80e-06

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 48.50  E-value: 6.80e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    282 KDLSQ--EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKNPQTVLWRYTGTRPSN-----------LANNTI 348
Cdd:PLN02207 257 QDLARrdELMKWLDDQPEASVVFLCFGSMGR-LRGPLVKEIAHGLELCQYRFLWSLRTEEVTNddllpegfldrVSGRGM 335

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 624725    349 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 402
Cdd:PLN02207 336 ICGWSPQVEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNAFLM 389
PLN03007 PLN03007
UDP-glucosyltransferase family protein
 300-444 1.00e-05

UDP-glucosyltransferase family protein


Pssm-ID: 178584 [Multi-domain]  Cd Length: 482  Bit Score: 47.93  E-value: 1.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    300 IVVFSLGSMVSeIPEKKAMAIADALGKNPQTVLW--RYTGTRPSN------------LANNTILVKWLPQNDLLGHPMTR 365
Cdd:PLN03007 287 VIYLSFGSVAS-FKNEQLFEIAAGLEGSGQNFIWvvRKNENQGEKeewlpegfeertKGKGLIIRGWAPQVLILDHQATG 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    366 AFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLEM--------TSEDLENALKAVINDKSYKE 436
Cdd:PLN03007 366 GFVTHCGWNSLLEGVAAGLPMVTWPVGAEQFYNEKLVtQVLRTGVSVGAKKLvkvkgdfiSREKVEKAVREVIVGEEAEE 445


                 ....*...
gi 624725    437 NIMRLSSL 444
Cdd:PLN03007 446 RRLRAKKL 453
PLN02208 PLN02208
glycosyltransferase family protein
 352-433 1.08e-05

glycosyltransferase family protein


Pssm-ID: 177858  Cd Length: 442  Bit Score: 48.09  E-value: 1.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    352 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALK 426
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQV-LFTRLMTEEFEVSVEVSRektgwFSKESLSNAIK 396


                 ....*..
gi 624725    427 AVINDKS 433
Cdd:PLN02208 397 SVMDKDS 403
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 368-448 2.88e-05

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 44.63  E-value: 2.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725     368 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSS 443
Cdd:pfam04101  76 ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNPLRLAEMAKASK 155


                  ....*
gi 624725     444 LHKDR 448
Cdd:pfam04101 156 ASGFK 160
PLN00414 PLN00414
glycosyltransferase family protein
 299-463 5.78e-05

glycosyltransferase family protein


Pssm-ID: 177807 [Multi-domain]  Cd Length: 446  Bit Score: 45.78  E-value: 5.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    299 GIVVFSLGSMVSEIPEKKAMAIADALgknPQTVLWRYTGtrpsnlaNNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYE 378
Cdd:PLN00414 276 GMELTGLPFLIAVMPPKGSSTVQEAL---PEGFEERVKG-------RGIVWEGWVEQPLILSHPSVGCFVNHCGFGSMWE 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    379 SICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALKAVINDKSYKENIMRLSSLH-KDRPVEP 452
Cdd:PLN00414 346 SLVSDCQIVFIPQLADQV-LITRLLTEELEVSVKVQRedsgwFSKESLRDTVKSVMDKDSEIGNLVKRNHKKlKETLVSP 424

                        170
                 ....*....|.
gi 624725    453 LDLAVFWVEFV 463
Cdd:PLN00414 425 GLLSGYADKFV 435
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 368-442 8.36e-05

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 44.90  E-value: 8.36e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   368 ITHAGSHGVYESICNGVPMVMMPLF----GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 439
Cdd:cd03785 257 ISRAGASTIAELTAAGKPAILIPYPyaadDHQEANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDperlKKMAEAAK 336


                ...
gi 624725   440 RLS 442
Cdd:cd03785 337 KLA 339
MurG COG0707
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ...
 368-442 1.84e-04

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440471 [Multi-domain]  Cd Length: 363  Bit Score: 43.96  E-value: 1.84e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   368 ITHAGSHGVYESICNGVPMVMMPL-F---GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 439
Cdd:COG0707 263 ISRAGASTVAELAALGKPAILVPLpHaadDHQTKNARALVEAGAAVLIPQSELTPEKLAEALEELLEDperlAKMAEAAR 342


                ...
gi 624725   440 RLS 442
Cdd:COG0707 343 ALA 345
PLN02764 PLN02764
glycosyltransferase family protein
 352-440 2.28e-04

glycosyltransferase family protein


Pssm-ID: 178364  Cd Length: 453  Bit Score: 43.90  E-value: 2.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725    352 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKgAGVTLNVLE-----MTSEDLENALK 426
Cdd:PLN02764 324 WVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIVLVPQLGDQVLNTRLLSDE-LKVSVEVAReetgwFSKESLRDAIN 402

                         90
                 ....*....|....
gi 624725    427 AVINDKSYKENIMR 440
Cdd:PLN02764 403 SVMKRDSEIGNLVK 416
PLN02670 PLN02670
transferase, transferring glycosyl groups
 348-409 3.18e-04

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 43.35  E-value: 3.18e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 624725    348 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 409
Cdd:PLN02670 342 IHVGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQGLNTRLLHGKKLGL 403
murG PRK00726
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
 368-440 1.42e-03

undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional


Pssm-ID: 234825 [Multi-domain]  Cd Length: 357  Bit Score: 40.88  E-value: 1.42e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 624725    368 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 440
Cdd:PRK00726 257 ICRAGASTVAELAAAGLPAILVPLphaaDDHQTANARALVDAGAALLIPQSDLTPEKLAEKLLELLSDPERLEAMAE 333
GT28_Beta-DGS-like cd17507
beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol ...
 356-441 1.89e-03

beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340861 [Multi-domain]  Cd Length: 364  Bit Score: 40.76  E-value: 1.89e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 624725   356 NDLLGhpMTRAFITHAGSHGVYESICNGVPMVM-MPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSY 434
Cdd:cd17507 262 NELMA--ASDLVITKPGGLTISEALARGLPVIIyDPIPGQEEENADFLENNGAGIIARDPEELLEIVARLIDPPSLLRMM 339


                ....*..
gi 624725   435 KENIMRL 441
Cdd:cd17507 340 SEAAKEL 346
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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