|
Name |
Accession |
Description |
Interval |
E-value |
| Involucrin_N |
pfam10583 |
Involucrin of squamous epithelia N-terminus; This is the N-terminal three beta strands of ... |
1-69 |
3.95e-15 |
|
Involucrin of squamous epithelia N-terminus; This is the N-terminal three beta strands of involucrin, a protein present in keratinocytes of epidermis and other stratified squamous epithelia. Involucrin first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane. Apigenin is a plant-derived flavanoid that has significant promise as a skin cancer chemopreventive agent. It has been found that apigenin regulates normal human keratinocyte differentiation by suppressing it and this is associated with reduced cell proliferation without apoptosis. The downstream part of the protein is represented by the family Involucrin, pfam00904.
Pssm-ID: 431372 Cd Length: 69 Bit Score: 70.29 E-value: 3.95e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536827 1 MSLQHTLPVTLSPALSQELLKTVPPPVNTQQEQMKPPTPLPPPCQKVPVKLPVEVPSKQEEKHMTAVKG 69
Cdd:pfam10583 1 MSQQHTLPVTLPPALSQEPLKTVSPPADTQQEQVKQPTPLPAPCQKVPSELPGEVPSEHEEKHTTPVKG 69
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
96-580 |
1.48e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 1.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 96 EEHQKAENPEQQLKQEKAQRDQQLNKQLEEEKKLLDQ--QLDQELVKRDEQLGMKKEQLLELPEQREGELKHLEQQKGQL 173
Cdd:COG1196 260 AELAELEAELEELRLELEELELELEEAQAEEYELLAElaRLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 174 ELpEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLElpEQQEGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQL 253
Cdd:COG1196 340 EE-LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE--ELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 254 KHLEQQKGQLELPEQQEGQLELPEQQEGQlelpEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQLNYLEQQEGQL 333
Cdd:COG1196 417 ERLEEELEELEEALAELEEEEEEEEEALE----EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 334 KHLDQQ-EKQPELPEQQVGQLKHLEKQEGQPKHL-------EQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGL 405
Cdd:COG1196 493 LLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 406 PEQQVRQLKQLEKEEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQEGQLEHLVQQEGQLEQQEGQVEHLEQQVGQLKHLEE 485
Cdd:COG1196 573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 486 QEGQLKHLEQQQGQLGVPEQQVGQPNNLEQEEKQLELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHLEQQEKQLEHPEQ 565
Cdd:COG1196 653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732
|
490
....*....|....*
gi 536827 566 QDGQLKHLEQQEGQL 580
Cdd:COG1196 733 EREELLEELLEEEEL 747
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
120-437 |
4.23e-09 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 60.01 E-value: 4.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 120 NKQLEEEKKlldQQLDQELVKRDEQLGMKKEQLLELPEQReGELKHLEQQK---GQLELPEQQEGQLELPEQQEGQLKHL 196
Cdd:TIGR00927 605 NKQIELWVK---EQLSRRPVAKVMALGDLSKGDVAEAEHT-GERTGEEGERpteAEGENGEESGGEAEQEGETETKGENE 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 197 EQQKGQLELPEQQEGQLELPEQQ---EGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQLkhlEQQKGQLELPEQQEGQL 273
Cdd:TIGR00927 681 SEGEIPAERKGEQEGEGEIEAKEadhKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEE---VEDEGEGEAEGKHEVET 757
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 274 ElPEQQEGQLELPEQQEGQLkhlEQQEGQLKHLENQEGQLEVPEEQVGQLNYLEQQEGQLKHLDQQEKQPELPEQQVGQl 353
Cdd:TIGR00927 758 E-GDRKETEHEGETEAEGKE---DEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDET- 832
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 354 khlEKQEGQPkhleqqEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVRQLKQLEKEEGQPKHLEEEEGQL 433
Cdd:TIGR00927 833 ---GEQELNA------ENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQ 903
|
....
gi 536827 434 KHLV 437
Cdd:TIGR00927 904 KQAI 907
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
96-391 |
4.40e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.06 E-value: 4.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 96 EEHQKAEnpEQQLKQEKAQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQL-----GMKKEQLLELPEQREG-ELKHLE-- 167
Cdd:PTZ00121 1480 EEAKKAD--EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeeAKKADEAKKAEEKKKAdELKKAEel 1557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 168 ---QQKGQLELPEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLE 244
Cdd:PTZ00121 1558 kkaEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ 1637
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 245 LPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQL--ELPEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQ 322
Cdd:PTZ00121 1638 LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKaeEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536827 323 LNYLEQQEGQLKHLDQQEKQPElpEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEG 391
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEA--EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
95-421 |
1.94e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.50 E-value: 1.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 95 HEEHQKAENPEQQLKQEKAQRDQQLNKQLEEEKKLLDQQLDQELVKRDE-QLGMKKEQLLELPEQREGELKHLEQQKGQL 173
Cdd:pfam02463 176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEyLLYLDYLKLNEERIDLLQELLRDEQEEIES 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 174 ELPEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQL 253
Cdd:pfam02463 256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 254 KHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQE-----GQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQLNYLEQ 328
Cdd:pfam02463 336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEeellaKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 329 QEGQLKHLDQQEKQPELPEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQ 408
Cdd:pfam02463 416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495
|
330
....*....|...
gi 536827 409 QVRQLKQLEKEEG 421
Cdd:pfam02463 496 EERSQKESKARSG 508
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Involucrin_N |
pfam10583 |
Involucrin of squamous epithelia N-terminus; This is the N-terminal three beta strands of ... |
1-69 |
3.95e-15 |
|
Involucrin of squamous epithelia N-terminus; This is the N-terminal three beta strands of involucrin, a protein present in keratinocytes of epidermis and other stratified squamous epithelia. Involucrin first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane. Apigenin is a plant-derived flavanoid that has significant promise as a skin cancer chemopreventive agent. It has been found that apigenin regulates normal human keratinocyte differentiation by suppressing it and this is associated with reduced cell proliferation without apoptosis. The downstream part of the protein is represented by the family Involucrin, pfam00904.
Pssm-ID: 431372 Cd Length: 69 Bit Score: 70.29 E-value: 3.95e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536827 1 MSLQHTLPVTLSPALSQELLKTVPPPVNTQQEQMKPPTPLPPPCQKVPVKLPVEVPSKQEEKHMTAVKG 69
Cdd:pfam10583 1 MSQQHTLPVTLPPALSQEPLKTVSPPADTQQEQVKQPTPLPAPCQKVPSELPGEVPSEHEEKHTTPVKG 69
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
96-580 |
1.48e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 1.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 96 EEHQKAENPEQQLKQEKAQRDQQLNKQLEEEKKLLDQ--QLDQELVKRDEQLGMKKEQLLELPEQREGELKHLEQQKGQL 173
Cdd:COG1196 260 AELAELEAELEELRLELEELELELEEAQAEEYELLAElaRLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 174 ELpEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLElpEQQEGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQL 253
Cdd:COG1196 340 EE-LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE--ELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 254 KHLEQQKGQLELPEQQEGQLELPEQQEGQlelpEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQLNYLEQQEGQL 333
Cdd:COG1196 417 ERLEEELEELEEALAELEEEEEEEEEALE----EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 334 KHLDQQ-EKQPELPEQQVGQLKHLEKQEGQPKHL-------EQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGL 405
Cdd:COG1196 493 LLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 406 PEQQVRQLKQLEKEEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQEGQLEHLVQQEGQLEQQEGQVEHLEQQVGQLKHLEE 485
Cdd:COG1196 573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 486 QEGQLKHLEQQQGQLGVPEQQVGQPNNLEQEEKQLELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHLEQQEKQLEHPEQ 565
Cdd:COG1196 653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732
|
490
....*....|....*
gi 536827 566 QDGQLKHLEQQEGQL 580
Cdd:COG1196 733 EREELLEELLEEEEL 747
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
105-457 |
5.14e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.65 E-value: 5.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 105 EQQLKQ-----EKAQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQREGELKHLEQQKGQLELpEQQ 179
Cdd:COG1196 199 ERQLEPlerqaEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL-ELE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 180 EGQLELPEQQEGQLKHLEQQkgqlelpEQQEGQLELPEQQEGQLELpEQQEGQLKHLEQQEGQLELPEQQEGQLKHLEQQ 259
Cdd:COG1196 278 ELELELEEAQAEEYELLAEL-------ARLEQDIARLEERRRELEE-RLEELEEELAELEEELEELEEELEELEEELEEA 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 260 KGQLELPEQQEGQLELpEQQEGQLELPEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQvgqlnyLEQQEGQLKHLDQQ 339
Cdd:COG1196 350 EEELEEAEAELAEAEE-ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA------EEALLERLERLEEE 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 340 EKQPELPEQQVGQLKHLEKQEgqpkHLEQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVRQLKQLEKE 419
Cdd:COG1196 423 LEELEEALAELEEEEEEEEEA----LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
|
330 340 350
....*....|....*....|....*....|....*...
gi 536827 420 EGQPKHLEEEEGQLKHLVQQEGQLEHLVQQEGQLEHLV 457
Cdd:COG1196 499 AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
96-592 |
1.48e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 1.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 96 EEHQKAENPEQQLKQEKAQRDQQLNKQLEEEKKLLDQQLdQELVKRDEQLGMKKEQLLELPEQREGELKHLEQQKGQL-- 173
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLEL-EELELELEEAQAEEYELLAELARLEQDIARLEERRRELee 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 174 -------ELPEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLE--LPEQQEGQLELPEQQEGQLKHLEQQEGQLE 244
Cdd:COG1196 317 rleeleeELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEeaLLEAEAELAEAEEELEELAEELLEALRAAA 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 245 LPEQQEGQLKHLEQQKGQLELpEQQEGQLELPEQQEGQLELPEQQEGQLkhLEQQEGQLKHLENQEGQLEVPEEQVGQLN 324
Cdd:COG1196 397 ELAAQLEELEEAEEALLERLE-RLEEELEELEEALAELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAA 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 325 YLEQQEGQLKHLDQQEKQPELPEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLG 404
Cdd:COG1196 474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVV 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 405 LPEQQVRQLKQLEKEEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQEGQLEHLVQQEGQLEQQEGQVEHLEQQVGQLKHLE 484
Cdd:COG1196 554 EDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 485 EQEGQLKHLEQQQGQLGVPEQQVGQPNNLEQEEKQLELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHLEQQEKQLEHPE 564
Cdd:COG1196 634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
|
490 500
....*....|....*....|....*...
gi 536827 565 QQDGQLKHLEQQEGQLKDLEQQKGQLEQ 592
Cdd:COG1196 714 EERLEEELEEEALEEQLEAEREELLEEL 741
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
120-437 |
4.23e-09 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 60.01 E-value: 4.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 120 NKQLEEEKKlldQQLDQELVKRDEQLGMKKEQLLELPEQReGELKHLEQQK---GQLELPEQQEGQLELPEQQEGQLKHL 196
Cdd:TIGR00927 605 NKQIELWVK---EQLSRRPVAKVMALGDLSKGDVAEAEHT-GERTGEEGERpteAEGENGEESGGEAEQEGETETKGENE 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 197 EQQKGQLELPEQQEGQLELPEQQ---EGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQLkhlEQQKGQLELPEQQEGQL 273
Cdd:TIGR00927 681 SEGEIPAERKGEQEGEGEIEAKEadhKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEE---VEDEGEGEAEGKHEVET 757
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 274 ElPEQQEGQLELPEQQEGQLkhlEQQEGQLKHLENQEGQLEVPEEQVGQLNYLEQQEGQLKHLDQQEKQPELPEQQVGQl 353
Cdd:TIGR00927 758 E-GDRKETEHEGETEAEGKE---DEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDET- 832
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 354 khlEKQEGQPkhleqqEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVRQLKQLEKEEGQPKHLEEEEGQL 433
Cdd:TIGR00927 833 ---GEQELNA------ENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQ 903
|
....
gi 536827 434 KHLV 437
Cdd:TIGR00927 904 KQAI 907
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
96-592 |
5.39e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.10 E-value: 5.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 96 EEHQKAENPEQQLKQEKAQRDQQLNKQLEEekklldqqLDQELVKRDEQLGMKKEQLLELPEQREGELKHLEQQKGQLEl 175
Cdd:COG1196 298 ARLEQDIARLEERRRELEERLEELEEELAE--------LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL- 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 176 pEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLElpEQQEGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQLKH 255
Cdd:COG1196 369 -EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE--EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 256 LEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQLNYLEQQEGQLKH 335
Cdd:COG1196 446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 336 LDQQEKQPELPEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEG---------QLKHLEQQEGQLEHLEHQEGQLGLP 406
Cdd:COG1196 526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratflpldKIRARAALAAALARGAIGAAVDLVA 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 407 EQQVRQLKQLEKEEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQEGQLEHLVQQEGQLEQQEGQVEHLEQQVGQLKHLEEQ 486
Cdd:COG1196 606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 487 EGQLKHLEQQQGQLGVPEQQVGQPNNLEQEEKQLELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHLEQQEKQLEHPEQQ 566
Cdd:COG1196 686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 536827 567 DGQLKHLEQQ-------------------------EGQLKDLEQQKGQLEQ 592
Cdd:COG1196 766 ERELERLEREiealgpvnllaieeyeeleerydflSEQREDLEEARETLEE 816
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
187-516 |
6.62e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 52.63 E-value: 6.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 187 EQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELpEQQEGQLKHLEQQEGQLELP-EQQEGQLKHLEQQKGQLEL 265
Cdd:COG1196 196 GELERQLEPLERQAEKAERYRELKEELKELEAELLLLKL-RELEAELEELEAELEELEAElEELEAELAELEAELEELRL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 266 pEQQEGQLELPEQQEGQLEL---PEQQEGQLKHLEQQ----EGQLKHLENQEGQLEvpEEQVGQLNYLEQQEGQLKHLDQ 338
Cdd:COG1196 275 -ELEELELELEEAQAEEYELlaeLARLEQDIARLEERrrelEERLEELEEELAELE--EELEELEEELEELEEELEEAEE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 339 QEKQPELPEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEgqlglpEQQVRQLKQLEK 418
Cdd:COG1196 352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL------ERLERLEEELEE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 419 EEGQPKHLEEEEGQLKHLVQ--QEGQLEHLVQQEGQLEHLVQQEGQLEQQEGQVEHLEQQVGQLKHLEEQEGQLKHLEQQ 496
Cdd:COG1196 426 LEEALAELEEEEEEEEEALEeaAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
|
330 340
....*....|....*....|
gi 536827 497 QGQLGVPEQQVGQPNNLEQE 516
Cdd:COG1196 506 FLEGVKAALLLAGLRGLAGA 525
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
237-553 |
1.27e-05 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 48.45 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 237 EQQEGQLELPEQQEGqlKHLEQQKGQLELPEQQEGQLElpEQQEGqlELPEQQEGqlkhleQQEGqlkhlenqEGQLEVP 316
Cdd:TIGR00927 643 ERTGEEGERPTEAEG--ENGEESGGEAEQEGETETKGE--NESEG--EIPAERKG------EQEG--------EGEIEAK 702
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 317 EEQVGQlnylEQQEGQLKHLDQQEKQPELPEQqvgqlkhlEKQEGQPKHLEQQEGqlehleEQEGQLKHLEQQEGQLEHL 396
Cdd:TIGR00927 703 EADHKG----ETEAEEVEHEGETEAEGTEDEG--------EIETGEEGEEVEDEG------EGEAEGKHEVETEGDRKET 764
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 397 EHQEGQLGLPEQQVRQLKQLEKEEGQPKHLEEEEGQLKHlvqqegqlEHLVQQEGQLEHLVQQEGQLEQQEGQVEHLEQQ 476
Cdd:TIGR00927 765 EHEGETEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEH--------EGETEAGEKDEHEGQSETQADDTEVKDETGEQE 836
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536827 477 VGQLKHLEEQEGQLKHLEQQQGQLGVPEQQVGQPNNLEQEEKQLELPEQQEGQlkhlEKQEAQLELPEQQVGQPKHL 553
Cdd:TIGR00927 837 LNAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEE----NEEPLSLEWPETRQKQAIYL 909
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
96-391 |
4.40e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.06 E-value: 4.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 96 EEHQKAEnpEQQLKQEKAQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQL-----GMKKEQLLELPEQREG-ELKHLE-- 167
Cdd:PTZ00121 1480 EEAKKAD--EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeeAKKADEAKKAEEKKKAdELKKAEel 1557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 168 ---QQKGQLELPEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLE 244
Cdd:PTZ00121 1558 kkaEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ 1637
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 245 LPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQL--ELPEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQ 322
Cdd:PTZ00121 1638 LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKaeEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536827 323 LNYLEQQEGQLKHLDQQEKQPElpEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEG 391
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEA--EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
257-563 |
5.12e-05 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 46.53 E-value: 5.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 257 EQQKGQLELPEQQEGqlELPEQQEGQLELPEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQLNylEQQEGQLKHL 336
Cdd:TIGR00927 643 ERTGEEGERPTEAEG--ENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKG--ETEAEEVEHE 718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 337 DQQEKQPELPEQqvgqlkhlEKQEGQPKHLEQQEGqlehleEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVRQLKQL 416
Cdd:TIGR00927 719 GETEAEGTEDEG--------EIETGEEGEEVEDEG------EGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQ 784
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 417 EKEEGQPKHLEEEEGQLKHLVQQEGQLEhlVQQEGQLEhlvqqegqleqqegqvehlEQQVGQLKHLEEQEGQLK---HL 493
Cdd:TIGR00927 785 AGEDGEMKGDEGAEGKVEHEGETEAGEK--DEHEGQSE-------------------TQADDTEVKDETGEQELNaenQG 843
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 494 EQQQGQLGVPEQQVGQPNNLEQEEKQLELPEQQEgqlkhlekQEAQLElpeqqvgqpkhlEQQEKQLEHP 563
Cdd:TIGR00927 844 EAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEE--------EEEEEE------------EEEEEENEEP 893
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
96-457 |
6.40e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 46.29 E-value: 6.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 96 EEHQKAEnpEQQLKQEKAQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQllelPEQREGELKHLEQQKGQLEL 175
Cdd:PTZ00121 1441 EEAKKAD--EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEE----AKKKADEAKKAAEAKKKADE 1514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 176 PEQQEgqlelPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEgQLKHLEQQEGQLELPEQQEGQLKH 255
Cdd:PTZ00121 1515 AKKAE-----EAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKK-KAEEAKKAEEDKNMALRKAEEAKK 1588
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 256 LEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEgQLKHLEQQEGQLKHLENQEgqlevpEEQVGQLNYLEQQEGQLKH 335
Cdd:PTZ00121 1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE-ELKKAEEEKKKVEQLKKKE------AEEKKKAEELKKAEEENKI 1661
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 336 LDQQEKQPElpEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQE-GQLEHLEHQEGQLGLPEQQVRqlK 414
Cdd:PTZ00121 1662 KAAEEAKKA--EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEkKKAEELKKAEEENKIKAEEAK--K 1737
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 536827 415 QLEKEEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQEGQLEHLV 457
Cdd:PTZ00121 1738 EAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
53-579 |
7.08e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 46.29 E-value: 7.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 53 VEVPSKQEEKHMTAVKGLPEQECEQQQQEPQEQEPQQQHWEQHEEHQKAE---NPEQQLKQEKAQRDQQLNKQLEEEKKL 129
Cdd:PTZ00121 1232 AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADelkKAEEKKKADEAKKAEEKKKADEAKKKA 1311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 130 LDQQLDQELVKRDEQLGMKKEQLLELPEQ--REGELKHLEQQKGQLELPEQQEGQLELPEQQEGQLKHLEQQKGQLELPE 207
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKKAEEakKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 208 QQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELPE 287
Cdd:PTZ00121 1392 KADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 288 QQEGQLKHLEQQEGQLKHLENQEG-----QLEVPEEQVGQLNYLEQQE-----GQLKHLDQQEKQPELPE-QQVGQLKHL 356
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAkkkadEAKKAAEAKKKADEAKKAEeakkaDEAKKAEEAKKADEAKKaEEKKKADEL 1551
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 357 EKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVR----QLKQLEKEEGQPKHLEEEEGQ 432
Cdd:PTZ00121 1552 KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKmkaeEAKKAEEAKIKAEELKKAEEE 1631
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 433 LKHLVQQEGQLEHLVQQEGQLEHlvQQEGQLEQQEGQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLGVPEQQVGQPNN 512
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKK--AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536827 513 LEQEEKQL--ELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHLEQQEKQLEHPEQQDGQLKHLEQQEGQ 579
Cdd:PTZ00121 1710 KEAEEKKKaeELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
54-629 |
1.87e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 44.75 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 54 EVPSKQEEKHMTAVKGLPEQECEQQQQEPQEQEPQQQHWEQHEEHQKAENPEQQ--LKQEKAQRDQQLNKQleEEKKLLD 131
Cdd:PTZ00121 1216 EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQaaIKAEEARKADELKKA--EEKKKAD 1293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 132 QQLDQELVKRDEQLGMKKEqllELPEQREGELKHLEQQKGQLELPEQQEgqlELPEQQEGQLKHLEQQKGQLELPEQQEG 211
Cdd:PTZ00121 1294 EAKKAEEKKKADEAKKKAE---EAKKADEAKKKAEEAKKKADAAKKKAE---EAKKAAEAAKAEAEAAADEAEAAEEKAE 1367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 212 QLELPEQQEGQL--ELPEQQEGQLKHLEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQ 289
Cdd:PTZ00121 1368 AAEKKKEEAKKKadAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAD 1447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 290 EGQLKHLEQQEGQlkhlenqegQLEVPEEQVGQLNYLEQQEGQLKHLDQQEKQPELPEQQVGQLKHLEKQEGQPKHLEQQ 369
Cdd:PTZ00121 1448 EAKKKAEEAKKAE---------EAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 370 E-----GQLEHLEEQEG--QLKHLEQQEGQLEHLEHQEGQLGLPEQQVRQLKQLEKEEGQPKHLEEEEGQLKHLVQQEGQ 442
Cdd:PTZ00121 1519 EeakkaDEAKKAEEAKKadEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 443 LEHLVQQEGQLEHLVQQEGQLEQQEG--QVEHLEQQVGQLKHLEEQE-GQLKHLEQQQGQLGVPEQQVGQPNnlEQEEKQ 519
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEElkKAEEEKKKVEQLKKKEAEEkKKAEELKKAEEENKIKAAEEAKKA--EEDKKK 1676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 520 LELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHLEQQEKQLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAP 599
Cdd:PTZ00121 1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756
|
570 580 590
....*....|....*....|....*....|
gi 536827 600 GQVQDIQPALPTKGELLLPVEHQQQKQEVQ 629
Cdd:PTZ00121 1757 KKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
96-394 |
2.91e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 96 EEHQKAENPEQQLKQEKAQRDQQLNkQLEEEKKLLDQQLdQELVKRDEQLGMKKEQLLELPEQREGELKHLEQQKGQLEl 175
Cdd:TIGR02169 681 ERLEGLKRELSSLQSELRRIENRLD-ELSQELSDASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK- 757
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 176 PEQQEGQLELPEQQEgqlkHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQ---QEGQLKHLEQQEGQLELPEQQ-EG 251
Cdd:TIGR02169 758 SELKELEARIEELEE----DLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEvsrIEARLREIEQKLNRLTLEKEYlEK 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 252 QLKHLEQQKGQLELPEQQEGQlelpEQQEGQLELPEQQEgqlkHLEQQEGQLKHLENQEGQLEvpeeqvGQLNYLEQQEG 331
Cdd:TIGR02169 834 EIQELQEQRIDLKEQIKSIEK----EIENLNGKKEELEE----ELEELEAALRDLESRLGDLK------KERDELEAQLR 899
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536827 332 QLKH-LDQQEKQPELPEQQVGQLK-HLEKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEGQLE 394
Cdd:TIGR02169 900 ELERkIEELEAQIEKKRKRLSELKaKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVE 964
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
296-592 |
2.91e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.16 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 296 LEQQEGQLKHLENQEGQLEVPEEQVGQLNYLEQQEGQLKHLDQQEKQpelpEQQVGQLKHLEKQegqpkhLEQQEGQLEH 375
Cdd:COG1196 195 LGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEL----EELEAELEELEAE------LEELEAELAE 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 376 LEEQEGQLKhLEQQEGQLEHLEHQEGQLGLPEQQVRQLKQLEKEEGQPKHLEEEEGQLKhlVQQEGQLEHLVQQEGQLEH 455
Cdd:COG1196 265 LEAELEELR-LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE--EELAELEEELEELEEELEE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 456 LVQQEGQLEQQEGQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLGVPEQQVGQPNNLEQEEKQLELPEQQEGQLKHLEK 535
Cdd:COG1196 342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 536827 536 QEAQLELPEQQVGQPKHLEQQEKQlehpEQQDGQLKHLEQQEGQLKDLEQQKGQLEQ 592
Cdd:COG1196 422 ELEELEEALAELEEEEEEEEEALE----EAAEEEAELEEEEEALLELLAELLEEAAL 474
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
107-415 |
3.04e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.89 E-value: 3.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 107 QLKQEKAQRDQQLNKQLEEEKKLLD----QQLDQELVKRDEQLGMKKEQLLEL-PEQREGELKHLEQQKGQLELPEQQEG 181
Cdd:TIGR02168 206 ERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELtAELQELEEKLEELRLEVSELEEEIEE 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 182 QLELPEQQEGQLKHLEQQKGQL--ELPEQQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLElpEQQEGQLKHLEQQ 259
Cdd:TIGR02168 286 LQKELYALANEISRLEQQKQILreRLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK--EELESLEAELEEL 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 260 KGQLELPEQQEGQLE--LPEQQEGQLELPEQQEGQLKHLEQQEGQLKHLEnqegqlevpEEQVGQLNYLEQQEGQLKHLD 337
Cdd:TIGR02168 364 EAELEELESRLEELEeqLETLRSKVAQLELQIASLNNEIERLEARLERLE---------DRRERLQQEIEELLKKLEEAE 434
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536827 338 QQEKQPELPEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEGQLK-HLEQQEGQLEHLEHQEGQLGLPEQQVRQLKQ 415
Cdd:TIGR02168 435 LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAErELAQLQARLDSLERLQENLEGFSEGVKALLK 513
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
359-592 |
9.63e-04 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 42.29 E-value: 9.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 359 QEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVRQLKQLEKEEGQPKHLEEEEGQLKHLVQ 438
Cdd:TIGR00927 653 TEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEI 732
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 439 QEGQLEHLVQQEGQLEHLVQQEGQLEQQEGQVEHLEQQVGQLKHlEEQEGQLKHLEQQQGQLGVPEQQVGQPNNLEQEEK 518
Cdd:TIGR00927 733 ETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKE-DEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGE 811
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536827 519 QLELPEQQEGQlkhLEKQEAQLELPEQQVGQPKHLE--QQEKQLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQ 592
Cdd:TIGR00927 812 KDEHEGQSETQ---ADDTEVKDETGEQELNAENQGEakQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEE 884
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
100-353 |
1.87e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.58 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 100 KAENPEQQLKQEKAQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQREGELKHLEQQKGQL-ELPEQ 178
Cdd:TIGR02168 273 RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLeELKEE 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 179 QEGQLELPEQQEGQLKHLEQQKGQL-ELPEQQEGQLELPEQQEGQLELP-EQQEGQLKHLEqqegqlelpEQQEGQLKHL 256
Cdd:TIGR02168 353 LESLEAELEELEAELEELESRLEELeEQLETLRSKVAQLELQIASLNNEiERLEARLERLE---------DRRERLQQEI 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 257 EQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQ-LNYLEQQEGQLKH 335
Cdd:TIGR02168 424 EELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArLDSLERLQENLEG 503
|
250
....*....|....*...
gi 536827 336 LDQQEKQPELPEQQVGQL 353
Cdd:TIGR02168 504 FSEGVKALLKNQSGLSGI 521
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
95-421 |
1.94e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.50 E-value: 1.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 95 HEEHQKAENPEQQLKQEKAQRDQQLNKQLEEEKKLLDQQLDQELVKRDE-QLGMKKEQLLELPEQREGELKHLEQQKGQL 173
Cdd:pfam02463 176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEyLLYLDYLKLNEERIDLLQELLRDEQEEIES 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 174 ELPEQQEGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQL 253
Cdd:pfam02463 256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 254 KHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQE-----GQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQLNYLEQ 328
Cdd:pfam02463 336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEeellaKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 329 QEGQLKHLDQQEKQPELPEQQVGQLKHLEKQEGQPKHLEQQEGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQ 408
Cdd:pfam02463 416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495
|
330
....*....|...
gi 536827 409 QVRQLKQLEKEEG 421
Cdd:pfam02463 496 EERSQKESKARSG 508
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
190-490 |
5.56e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 40.04 E-value: 5.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 190 EGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLELPEQQEGQLKHLEQQKGQLELpEQQ 269
Cdd:TIGR02168 199 ERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL-EVS 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 270 EGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLKHLENQEGQLEVPEEQVGQ--------LNYLEQQEGQLK--HLDQQ 339
Cdd:TIGR02168 278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESkldelaeeLAELEEKLEELKeeLESLE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536827 340 EKQPELPEQQVGQLKHLEKQEgqpKHLEQQEGQLEHLEEQEGQL-KHLEQQEGQLEHLEHQEGQLglpEQQVRQLKQLEK 418
Cdd:TIGR02168 358 AELEELEAELEELESRLEELE---EQLETLRSKVAQLELQIASLnNEIERLEARLERLEDRRERL---QQEIEELLKKLE 431
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536827 419 EEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQEGQLEHLVQQEGQLEQQEGqvEHLEQQVGQLKHLEEQEGQL 490
Cdd:TIGR02168 432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAE--RELAQLQARLDSLERLQENL 501
|
|
| |
