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Conserved domains on  [gi|756142826|pdb|4TXQ|B]
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Chain B, Vacuolar protein sorting-associated protein VTA1 homolog

Protein Classification

Vta1 family protein( domain architecture ID 11152027)

Vta1 (VPS20-associated protein 1) family protein similar to vacuolar protein sorting-associated protein VTA1 that is involved in the endosomal multivesicular bodies (MVB) pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Vta1 pfam04652
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ...
 23-153 2.05e-62

Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region.


:

Pssm-ID: 461380  Cd Length: 133  Bit Score: 188.16  E-value: 2.05e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4TXQ_B         23 RTAQEHDKRDPVVAYYCRLYAMQTGMKIDSKT--PECRKFLSKLMDQLEALKKQLGDNEAITQEIVGCAHLENYALKMFL 100
Cdd:pfam04652   1 KRAQELEKADPVVAYYCRLYAVQQILKLGLHKkdKEVRAFLTKLLDKLEQFKKELGDNEAITDEVAAQAYVENFALKLFN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
4TXQ_B        101 YADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYI 153
Cdd:pfam04652  81 RADKEDRAGRATKQTAKTFYAAATFFEVLQIFGELDEEIAKKIKYAKWKAARI 133
 
Name Accession Description Interval E-value
Vta1 pfam04652
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ...
 23-153 2.05e-62

Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region.


Pssm-ID: 461380  Cd Length: 133  Bit Score: 188.16  E-value: 2.05e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4TXQ_B         23 RTAQEHDKRDPVVAYYCRLYAMQTGMKIDSKT--PECRKFLSKLMDQLEALKKQLGDNEAITQEIVGCAHLENYALKMFL 100
Cdd:pfam04652   1 KRAQELEKADPVVAYYCRLYAVQQILKLGLHKkdKEVRAFLTKLLDKLEQFKKELGDNEAITDEVAAQAYVENFALKLFN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
4TXQ_B        101 YADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYI 153
Cdd:pfam04652  81 RADKEDRAGRATKQTAKTFYAAATFFEVLQIFGELDEEIAKKIKYAKWKAARI 133
 
Name Accession Description Interval E-value
Vta1 pfam04652
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ...
 23-153 2.05e-62

Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region.


Pssm-ID: 461380  Cd Length: 133  Bit Score: 188.16  E-value: 2.05e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4TXQ_B         23 RTAQEHDKRDPVVAYYCRLYAMQTGMKIDSKT--PECRKFLSKLMDQLEALKKQLGDNEAITQEIVGCAHLENYALKMFL 100
Cdd:pfam04652   1 KRAQELEKADPVVAYYCRLYAVQQILKLGLHKkdKEVRAFLTKLLDKLEQFKKELGDNEAITDEVAAQAYVENFALKLFN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
4TXQ_B        101 YADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYI 153
Cdd:pfam04652  81 RADKEDRAGRATKQTAKTFYAAATFFEVLQIFGELDEEIAKKIKYAKWKAARI 133
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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