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Conserved domains on  [gi|480312255|pdb|4J7C|J]
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Chain J, Ktr system potassium uptake protein B

Protein Classification

TrkH family potassium uptake protein( domain architecture ID 11489990)

TrkH family potassium uptake protein similar to Bacillus subtilis Ktr system potassium uptake protein B (KtrB) which is an integral membrane subunit of the KtrAB potassium uptake transporter

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a38 TIGR00933
potassium uptake protein, TrkH family; The proteins of the Trk family are derived from ...
54-437 1.57e-124

potassium uptake protein, TrkH family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds]


:

Pssm-ID: 273349  Cd Length: 391  Bit Score: 367.75  E-value: 1.57e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J         54 LLMLP--ISTTKPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMILGKKIGLKER 131
Cdd:TIGR00933   1 LLALPfvISSGLPLSFIDALFTATSAVTTTGLTVLDTLESLPKAGLFLRSLLQQIGGLGFMVLAVAILILLGKKISLGAR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        132 MLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGwsSGLFASLFHAISAFNNAGFSLWPDNLMSYVGD 211
Cdd:TIGR00933  81 LYLAEALGPLSDDKLLPLIKNTAKFIFVIYLLGTILLAVRFVLTGW--MPLFDAIFHSISAFNNGGFSTHSDSSIGYFHD 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        212 PTVNLVITFLFITGGIGFTVLFDVM---KNRRFKTFSLHTKLMLTGTLMLNAIAMLTVFILEYSNpgTLGHLHIVDKLWA 288
Cdd:TIGR00933 159 PSVNLVIAFLIILGGLGFTVHYDVYlhlRKRVFKSLSLDTKVRLFVTFLLLAIGFILFLLLERGN--TLYSYSFGALLLS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        289 SYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLR-GKKETVIFRRSIKYPI 367
Cdd:TIGR00933 237 AFFQSSTLRTAGFSTIDFAALPTATLVLLLLLMFIGGCSGSTAGGIKTTTFAILLKQVYREIRrGIHPRIIFSRRIGGKT 316
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
4J7C_J        368 IIKALAVSVTSLFIVFLGIFALTITE----QAPFLQIVFETFSAFGTVGLTMGL-TPELTTAGKCIIIVIMFIGR 437
Cdd:TIGR00933 317 IDKAILISVWSFFLVFALIFLLSILElissGYDFLTSLFEVVSAFGTVGLSVGLtTANLPDAGKLILIVLMFIGR 391
 
Name Accession Description Interval E-value
2a38 TIGR00933
potassium uptake protein, TrkH family; The proteins of the Trk family are derived from ...
54-437 1.57e-124

potassium uptake protein, TrkH family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273349  Cd Length: 391  Bit Score: 367.75  E-value: 1.57e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J         54 LLMLP--ISTTKPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMILGKKIGLKER 131
Cdd:TIGR00933   1 LLALPfvISSGLPLSFIDALFTATSAVTTTGLTVLDTLESLPKAGLFLRSLLQQIGGLGFMVLAVAILILLGKKISLGAR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        132 MLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGwsSGLFASLFHAISAFNNAGFSLWPDNLMSYVGD 211
Cdd:TIGR00933  81 LYLAEALGPLSDDKLLPLIKNTAKFIFVIYLLGTILLAVRFVLTGW--MPLFDAIFHSISAFNNGGFSTHSDSSIGYFHD 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        212 PTVNLVITFLFITGGIGFTVLFDVM---KNRRFKTFSLHTKLMLTGTLMLNAIAMLTVFILEYSNpgTLGHLHIVDKLWA 288
Cdd:TIGR00933 159 PSVNLVIAFLIILGGLGFTVHYDVYlhlRKRVFKSLSLDTKVRLFVTFLLLAIGFILFLLLERGN--TLYSYSFGALLLS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        289 SYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLR-GKKETVIFRRSIKYPI 367
Cdd:TIGR00933 237 AFFQSSTLRTAGFSTIDFAALPTATLVLLLLLMFIGGCSGSTAGGIKTTTFAILLKQVYREIRrGIHPRIIFSRRIGGKT 316
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
4J7C_J        368 IIKALAVSVTSLFIVFLGIFALTITE----QAPFLQIVFETFSAFGTVGLTMGL-TPELTTAGKCIIIVIMFIGR 437
Cdd:TIGR00933 317 IDKAILISVWSFFLVFALIFLLSILElissGYDFLTSLFEVVSAFGTVGLSVGLtTANLPDAGKLILIVLMFIGR 391
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
36-460 3.57e-116

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 347.07  E-value: 3.57e-116
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       36 PPQVLAIGFFLTIIIGAVLLMLPISTT-KPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTF 114
Cdd:COG0168   1 PAREGFLIVALVWLVGALLLALPFALSgGGLSFLDALFEAVSGVTTTGLTVVDTLDTLPKFGLLWRSLLQWLGGLGIIVL 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J      115 AVLIVMILgkkiGLKERMLVQ-EALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRlvpqygwSSGLFASLFHAISAF 193
Cdd:COG0168  81 AVAILPLL----GIGGRQLFQaELPNEKLLPRIVRTAKALWLIYLGLTLIGALLLWLA-------GMALFDAIFHAFSAF 149
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J      194 NNAGFSLWPDNLMSYvGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTFSLHTKLMLTGTLMLNAIAMLTVFILeysN 273
Cdd:COG0168 150 STGGFSTHDDSLGAF-NSPAIELVIIVFMILGGLGFPVHYDLLRYRRFRRLFSDTELRLYLTLILLVVGLLALFLW---N 225
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J      274 PGTLGHLHivDKLWASYFQAVTP-RTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLRG 352
Cdd:COG0168 226 NGTLGSLG--EALRAALFQVVSIlTTTGFATVDYGQWPPFSLLLLILLMFIGGSAGSTAGGIKVTRFAVLLKAIRRELRR 303
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J      353 KK------ETVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALTITEQAPFLQIVFETFSAFGTVGLTMGLTP-ELTTAG 425
Cdd:COG0168 304 LIhpnavrPVRIGGRRIPEEVIRKALAFFFLYLLLVVVGTLLLSLTEGLDFLTALFEVASAFGNVGLSLGITGaSLSDAG 383
                       410       420       430
                ....*....|....*....|....*....|....*
4J7C_J      426 KCIIIVIMFIGRIGPLTFVFSFAKTeqsnIRYPDG 460
Cdd:COG0168 384 KLVLIFLMLLGRLEILTVLVLLTPR----FRWREE 414
TrkH pfam02386
Cation transport protein; This family consists of various cation transport proteins (Trk) and ...
63-455 1.26e-55

Cation transport protein; This family consists of various cation transport proteins (Trk) and V-type sodium ATP synthase subunit J or translocating ATPase J EC:3.6.1.34. These proteins are involved in active sodium up-take utilizing ATP in the process. TrkH a member of the family from E. coli is a hydrophobic membrane protein and determines the specificity and kinetics of cation transport by the TrK system in E. coli.


Pssm-ID: 280534  Cd Length: 491  Bit Score: 192.25  E-value: 1.26e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J         63 KPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMILGK-KIGLKERMLVQEALNQP 141
Cdd:pfam02386  59 PSLTFLDALFEAVSGLTTTGLTVIDVETSLPRSGLFYRAQLQWIGGLGTMVLAVLSWPTLGRgSAFLYLSEMQGPELGGK 138
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        142 TIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGWSSG--LFASLFHAISAFNNAGFSLWPDNLMSYVGDPTVNLVIT 219
Cdd:pfam02386 139 EYPSLSELCKILWVYYFGLTILAFVAYFVFIYTAKGYLEVvpLWWAFFHSMSAFSNGGFSLTPNSIASFNTNPVILWVAT 218
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        220 FLFITGGIGFTVLFDVMKNRRFKT--------------------FSLHTKLMLTGTLMLNAIAM----LTVFILEYSNPG 275
Cdd:pfam02386 219 SFIILGGIGFPIHLRVIIWIMKKIlrfknfkeslsllldhprrcFTLLFASGFTWVLFLELAVLnvtdWILFMVLDFGSH 298
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        276 TLGHLHIVDKLWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLRGKKE 355
Cdd:pfam02386 299 VVGSIPKGYRVLNAFFQSVSTRTAGFSVVDISNLHPAIKVSYVLMMFIGGAPGSTAGGIKRTRVYEEFSLGKYEIHGDPE 378
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        356 -TVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALT---ITEQAPF--LQIVFETFSAFGTVGLTMG----LTPELTTAG 425
Cdd:pfam02386 379 pRAVSTKSIDGKHLTRQLSEDLWYLFLGLFIICICEglkLSDVGPFsfFDILFEVVSAYGTVGLSLGtnhsLSAQFTTIA 458
                         410       420       430
                  ....*....|....*....|....*....|
4J7C_J        426 KCIIIVIMFIGRIGPLTFVFSFAKTEQSNI 455
Cdd:pfam02386 459 KLVIIALMIRGRLEGLPVLLDFAILPSDKS 488
PRK10750 PRK10750
Trk system potassium transporter TrkH;
49-450 8.37e-05

Trk system potassium transporter TrkH;


Pssm-ID: 182698  Cd Length: 483  Bit Score: 44.82  E-value: 8.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        49 IIGAVLLMLPISTTKP-LSWIDALFTAASATTVTG---LAVVDTGTQFTVFGQTVIMGLiqiGGLGFMTFAVLIVMILGK 124
Cdd:PRK10750  79 VLGSVGALPFIFSESPnLTITDAFFESFSGLTTTGattLVGLDSLPHAILFYRQMLQWF---GGMGIIVLAVAILPILGV 155
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       125 KIGLKERMLVQEALNQPTIGGVIG-LVKVLFLFSISIELIAALILsirlvpqygWSSGL--FASLFHAISAFNNAGFSLw 201
Cdd:PRK10750 156 GGMQLYRAEMPGPLKDNKMRPRIAeTAKTLWLIYVLLTVACALAL---------WFAGMdaFDAIGHSFSTIAIGGFST- 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       202 PDNLMSYVGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTF--SLHTKLMLTGTLMLNAIAMLTVFILEYSNPGtlgh 279
Cdd:PRK10750 226 HDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYwrDPEFRMFIGVQLTLVVICTLVLWFHNVYSSA---- 301
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       280 lhiVDKLWASYFQAVT-PRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVIltsviaYLRGKKE-TV 357
Cdd:PRK10750 302 ---LMTLNQAFFQVVSmATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLL------FKQGNRElKR 372
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       358 IFRRSIKYPIII--KALAVSVTSLFIVFLGIFALT-ITEQAPFLQIVFETFSAFGTVGLTM-GLTPELTT---------- 423
Cdd:PRK10750 373 LVHPNAVYSIKLgnRALPERILEAVWGFFSAYALVfIVSMLAIIATGVDDFSAFASVVATLnNLGPGLGVvadnftsmnp 452
                        410       420
                 ....*....|....*....|....*..
4J7C_J       424 AGKCIIIVIMFIGRIGPLTFVFSFAKT 450
Cdd:PRK10750 453 VAKWILIANMLFGRLEVFTLLVLFTPT 479
 
Name Accession Description Interval E-value
2a38 TIGR00933
potassium uptake protein, TrkH family; The proteins of the Trk family are derived from ...
54-437 1.57e-124

potassium uptake protein, TrkH family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273349  Cd Length: 391  Bit Score: 367.75  E-value: 1.57e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J         54 LLMLP--ISTTKPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMILGKKIGLKER 131
Cdd:TIGR00933   1 LLALPfvISSGLPLSFIDALFTATSAVTTTGLTVLDTLESLPKAGLFLRSLLQQIGGLGFMVLAVAILILLGKKISLGAR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        132 MLVQEALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGwsSGLFASLFHAISAFNNAGFSLWPDNLMSYVGD 211
Cdd:TIGR00933  81 LYLAEALGPLSDDKLLPLIKNTAKFIFVIYLLGTILLAVRFVLTGW--MPLFDAIFHSISAFNNGGFSTHSDSSIGYFHD 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        212 PTVNLVITFLFITGGIGFTVLFDVM---KNRRFKTFSLHTKLMLTGTLMLNAIAMLTVFILEYSNpgTLGHLHIVDKLWA 288
Cdd:TIGR00933 159 PSVNLVIAFLIILGGLGFTVHYDVYlhlRKRVFKSLSLDTKVRLFVTFLLLAIGFILFLLLERGN--TLYSYSFGALLLS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        289 SYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLR-GKKETVIFRRSIKYPI 367
Cdd:TIGR00933 237 AFFQSSTLRTAGFSTIDFAALPTATLVLLLLLMFIGGCSGSTAGGIKTTTFAILLKQVYREIRrGIHPRIIFSRRIGGKT 316
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
4J7C_J        368 IIKALAVSVTSLFIVFLGIFALTITE----QAPFLQIVFETFSAFGTVGLTMGL-TPELTTAGKCIIIVIMFIGR 437
Cdd:TIGR00933 317 IDKAILISVWSFFLVFALIFLLSILElissGYDFLTSLFEVVSAFGTVGLSVGLtTANLPDAGKLILIVLMFIGR 391
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
36-460 3.57e-116

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 347.07  E-value: 3.57e-116
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       36 PPQVLAIGFFLTIIIGAVLLMLPISTT-KPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTF 114
Cdd:COG0168   1 PAREGFLIVALVWLVGALLLALPFALSgGGLSFLDALFEAVSGVTTTGLTVVDTLDTLPKFGLLWRSLLQWLGGLGIIVL 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J      115 AVLIVMILgkkiGLKERMLVQ-EALNQPTIGGVIGLVKVLFLFSISIELIAALILSIRlvpqygwSSGLFASLFHAISAF 193
Cdd:COG0168  81 AVAILPLL----GIGGRQLFQaELPNEKLLPRIVRTAKALWLIYLGLTLIGALLLWLA-------GMALFDAIFHAFSAF 149
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J      194 NNAGFSLWPDNLMSYvGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTFSLHTKLMLTGTLMLNAIAMLTVFILeysN 273
Cdd:COG0168 150 STGGFSTHDDSLGAF-NSPAIELVIIVFMILGGLGFPVHYDLLRYRRFRRLFSDTELRLYLTLILLVVGLLALFLW---N 225
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J      274 PGTLGHLHivDKLWASYFQAVTP-RTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLRG 352
Cdd:COG0168 226 NGTLGSLG--EALRAALFQVVSIlTTTGFATVDYGQWPPFSLLLLILLMFIGGSAGSTAGGIKVTRFAVLLKAIRRELRR 303
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J      353 KK------ETVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALTITEQAPFLQIVFETFSAFGTVGLTMGLTP-ELTTAG 425
Cdd:COG0168 304 LIhpnavrPVRIGGRRIPEEVIRKALAFFFLYLLLVVVGTLLLSLTEGLDFLTALFEVASAFGNVGLSLGITGaSLSDAG 383
                       410       420       430
                ....*....|....*....|....*....|....*
4J7C_J      426 KCIIIVIMFIGRIGPLTFVFSFAKTeqsnIRYPDG 460
Cdd:COG0168 384 KLVLIFLMLLGRLEILTVLVLLTPR----FRWREE 414
TrkH pfam02386
Cation transport protein; This family consists of various cation transport proteins (Trk) and ...
63-455 1.26e-55

Cation transport protein; This family consists of various cation transport proteins (Trk) and V-type sodium ATP synthase subunit J or translocating ATPase J EC:3.6.1.34. These proteins are involved in active sodium up-take utilizing ATP in the process. TrkH a member of the family from E. coli is a hydrophobic membrane protein and determines the specificity and kinetics of cation transport by the TrK system in E. coli.


Pssm-ID: 280534  Cd Length: 491  Bit Score: 192.25  E-value: 1.26e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J         63 KPLSWIDALFTAASATTVTGLAVVDTGTQFTVFGQTVIMGLIQIGGLGFMTFAVLIVMILGK-KIGLKERMLVQEALNQP 141
Cdd:pfam02386  59 PSLTFLDALFEAVSGLTTTGLTVIDVETSLPRSGLFYRAQLQWIGGLGTMVLAVLSWPTLGRgSAFLYLSEMQGPELGGK 138
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        142 TIGGVIGLVKVLFLFSISIELIAALILSIRLVPQYGWSSG--LFASLFHAISAFNNAGFSLWPDNLMSYVGDPTVNLVIT 219
Cdd:pfam02386 139 EYPSLSELCKILWVYYFGLTILAFVAYFVFIYTAKGYLEVvpLWWAFFHSMSAFSNGGFSLTPNSIASFNTNPVILWVAT 218
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        220 FLFITGGIGFTVLFDVMKNRRFKT--------------------FSLHTKLMLTGTLMLNAIAM----LTVFILEYSNPG 275
Cdd:pfam02386 219 SFIILGGIGFPIHLRVIIWIMKKIlrfknfkeslsllldhprrcFTLLFASGFTWVLFLELAVLnvtdWILFMVLDFGSH 298
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        276 TLGHLHIVDKLWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVILTSVIAYLRGKKE 355
Cdd:pfam02386 299 VVGSIPKGYRVLNAFFQSVSTRTAGFSVVDISNLHPAIKVSYVLMMFIGGAPGSTAGGIKRTRVYEEFSLGKYEIHGDPE 378
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        356 -TVIFRRSIKYPIIIKALAVSVTSLFIVFLGIFALT---ITEQAPF--LQIVFETFSAFGTVGLTMG----LTPELTTAG 425
Cdd:pfam02386 379 pRAVSTKSIDGKHLTRQLSEDLWYLFLGLFIICICEglkLSDVGPFsfFDILFEVVSAYGTVGLSLGtnhsLSAQFTTIA 458
                         410       420       430
                  ....*....|....*....|....*....|
4J7C_J        426 KCIIIVIMFIGRIGPLTFVFSFAKTEQSNI 455
Cdd:pfam02386 459 KLVIIALMIRGRLEGLPVLLDFAILPSDKS 488
2a38euk TIGR00934
potassium uptake protein, Trk family; The proteins of the Trk family are derived from ...
149-443 9.22e-20

potassium uptake protein, Trk family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. This family is specific for the eukaryotic Trk system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130009 [Multi-domain]  Cd Length: 800  Bit Score: 92.35  E-value: 9.22e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        149 LVKVLFLFSISIELIAALIL---------SIRLVPQYGWSSGLFaSLFHAISAFNNAGFSLWPDNLMSYVGDPTVNLVIT 219
Cdd:TIGR00934 451 LCSIVLVYFLGFNILGFVLLlpwinhvktYSEVVRSKGVSPTWW-GFFTAMSAFANLGLTLTPESMVSFNKNSYLLLLMI 529
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        220 FLFITGGIGFTVLF------------DVMKNRRFKTF--------------SLHTKLMLTGTLMLNAIAMLTVFILEYsN 273
Cdd:TIGR00934 530 WFIIIGNTGFPIFLrliiwilfkispDLSKRKESLGFlldhprrcftllfpSGATWWLFFTLVGLNAIDLILFIILDW-G 608
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        274 PGTLGHLHIVDKLWASYFQAVTPRTAGFNSLDFGSMREGTIVFTLLLMFIgaGSASTASGIKLTTFIVILTSVIAYLRGK 353
Cdd:TIGR00934 609 SSVVDGLSKGIKVLNGLFQSVSTRTAGFTVVDLSQLHPAIQVSYMLMMYV--SVLPLAISIRRTNVYEEQSLGLYNEENE 686
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        354 K-ETVIFRRSIKYPIIIKALAVsvtSLFIVFLGIFALTITE-------QAP---FLQIVFETFSAFGTVGLTMG------ 416
Cdd:TIGR00934 687 EhEGESSTKSFIGAHLRRQLSF---DLWYIFLGLFIICICEgrkiqdpDPPnfnVFNILFEVVSAYGTVGLSLGyscsny 763
                         330       340
                  ....*....|....*....|....*...
4J7C_J        417 -LTPELTTAGKCIIIVIMFIGRIGPLTF 443
Cdd:TIGR00934 764 sFSGQFTTLSKLVIIAMLIRGRHRGLPY 791
2a38euk TIGR00934
potassium uptake protein, Trk family; The proteins of the Trk family are derived from ...
26-112 5.74e-08

potassium uptake protein, Trk family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. This family is specific for the eukaryotic Trk system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130009 [Multi-domain]  Cd Length: 800  Bit Score: 55.37  E-value: 5.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J         26 DKVIKWVRFT----PPQVLAIGFFLTIIIGAVLLML--PiSTTKPLSWIDALFTAASATTVTGLAVVDTgTQFTVFGQTV 99
Cdd:TIGR00934  28 AKIAKVCRPLakyvFPFFIAVHYFYIISLTIIASILlyP-STVKNPAYIDALFLAAGALTQGGLNTVDM-NDLSLYQQIV 105
                          90
                  ....*....|...
4J7C_J        100 IMGLIQIGGLGFM 112
Cdd:TIGR00934 106 LYILMLLTTPIFV 118
PRK10750 PRK10750
Trk system potassium transporter TrkH;
49-450 8.37e-05

Trk system potassium transporter TrkH;


Pssm-ID: 182698  Cd Length: 483  Bit Score: 44.82  E-value: 8.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J        49 IIGAVLLMLPISTTKP-LSWIDALFTAASATTVTG---LAVVDTGTQFTVFGQTVIMGLiqiGGLGFMTFAVLIVMILGK 124
Cdd:PRK10750  79 VLGSVGALPFIFSESPnLTITDAFFESFSGLTTTGattLVGLDSLPHAILFYRQMLQWF---GGMGIIVLAVAILPILGV 155
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       125 KIGLKERMLVQEALNQPTIGGVIG-LVKVLFLFSISIELIAALILsirlvpqygWSSGL--FASLFHAISAFNNAGFSLw 201
Cdd:PRK10750 156 GGMQLYRAEMPGPLKDNKMRPRIAeTAKTLWLIYVLLTVACALAL---------WFAGMdaFDAIGHSFSTIAIGGFST- 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       202 PDNLMSYVGDPTVNLVITFLFITGGIGFTVLFDVMKNRRFKTF--SLHTKLMLTGTLMLNAIAMLTVFILEYSNPGtlgh 279
Cdd:PRK10750 226 HDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYwrDPEFRMFIGVQLTLVVICTLVLWFHNVYSSA---- 301
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       280 lhiVDKLWASYFQAVT-PRTAGFNSLDFGSMREGTIVFTLLLMFIGAGSASTASGIKLTTFIVIltsviaYLRGKKE-TV 357
Cdd:PRK10750 302 ---LMTLNQAFFQVVSmATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLL------FKQGNRElKR 372
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_J       358 IFRRSIKYPIII--KALAVSVTSLFIVFLGIFALT-ITEQAPFLQIVFETFSAFGTVGLTM-GLTPELTT---------- 423
Cdd:PRK10750 373 LVHPNAVYSIKLgnRALPERILEAVWGFFSAYALVfIVSMLAIIATGVDDFSAFASVVATLnNLGPGLGVvadnftsmnp 452
                        410       420
                 ....*....|....*....|....*..
4J7C_J       424 AGKCIIIVIMFIGRIGPLTFVFSFAKT 450
Cdd:PRK10750 453 VAKWILIANMLFGRLEVFTLLVLFTPT 479
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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