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Conserved domains on  [gi|480312246|pdb|4J7C|A]
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Chain A, Ktr system potassium uptake protein A

Protein Classification

potassium channel family protein( domain architecture ID 11426271)

potassium channel family protein spans the cell membrane to form a conduction pathway or pore, through which selective ions such as potassium, sodium, and calcium translocate across cell membranes, similar to Trk system potassium uptake protein TrkA

CATH:  1.20.5.870|3.30.70.1450|3.40.50.720
Gene Ontology:  GO:0016020|GO:0022857|GO:0030001|GO:0034220
PubMed:  15816170|9525859|11836519|1772658|11178249
SCOP:  4000005|4000027
TCDB:  1.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 5-206 6.76e-50

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


:

Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 164.08  E-value: 6.76e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A        5 KNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIG---AN 81
Cdd:COG0569  94 LKMHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEDVLVIVGDATDEEVLEEAGIEDADAVIAATGddeAN 173

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A       82 IQAStlttLLLKELDIPNIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSD-EYSIVELLATR 160
Cdd:COG0569 174 ILAC----LLAKELGVPRIIARANDPEYADLLERLGADVVISPERLAARRIARLLLRPGVLDVLELADgDAEIVEVTVPE 249

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
4J7C_A      161 --KLDSKSIIDLNVRAKYGCTILAIKHHGDIcLSPAPEDIIREQDCLV 206
Cdd:COG0569 250 gsPLVGKTLKELDLRERYGVTVVAIKRGGEV-IIPSGDTVLEAGDELI 296
 
Name Accession Description Interval E-value
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 5-206 6.76e-50

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 164.08  E-value: 6.76e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A        5 KNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIG---AN 81
Cdd:COG0569  94 LKMHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEDVLVIVGDATDEEVLEEAGIEDADAVIAATGddeAN 173

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A       82 IQAStlttLLLKELDIPNIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSD-EYSIVELLATR 160
Cdd:COG0569 174 ILAC----LLAKELGVPRIIARANDPEYADLLERLGADVVISPERLAARRIARLLLRPGVLDVLELADgDAEIVEVTVPE 249

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
4J7C_A      161 --KLDSKSIIDLNVRAKYGCTILAIKHHGDIcLSPAPEDIIREQDCLV 206
Cdd:COG0569 250 gsPLVGKTLKELDLRERYGVTVVAIKRGGEV-IIPSGDTVLEAGDELI 296
TrkA_N pfam02254
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ...
 9-124 5.36e-25

TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.


Pssm-ID: 426679 [Multi-domain]  Cd Length: 115  Bit Score: 94.51  E-value: 5.36e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A          9 FAVIGLGRFGGSIVKELHRmGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIGaNIQASTLT 88
Cdd:pfam02254   1 IIIIGYGRVGRSLAEELSE-GGDVVVIDKDEERVEELREEGVPVVVGDATDEEVLEEAGIEEADAVIAATG-DDEANILI 78

                          90       100       110
                  ....*....|....*....|....*....|....*..
4J7C_A         89 TLLLKEL-DIPNIWVKAQNYYHHKVLEKIGADRIIHP 124
Cdd:pfam02254  79 VLLARELnPDKKIIARANDPEHAELLRRLGADHVISP 115
trkA PRK09496
Trk system potassium transporter TrkA;
11-220 3.79e-09

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 55.90  E-value: 3.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A        11 VIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNaYASYAT--HAVIANATEENELLSLGIRNFEYVIVAIG---ANIQAS 85
Cdd:PRK09496   5 IVGAGQVGYTLAENLSGENNDVTVIDTDEERLR-RLQDRLdvRTVVGNGSSPDVLREAGAEDADLLIAVTDsdeTNMVAC 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A        86 tlttLLLKEL-DIPN--IWVKAQNYYHHKVL---EKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSD-EYSIVELLA 158
Cdd:PRK09496  84 ----QIAKSLfGAPTtiARVRNPEYAEYDKLfskEALGIDLLISPELLVAREIARLIEYPGALDVEEFADgRVQLVEVKV 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
4J7C_A       159 TR--KLDSKSIIDLN-VRAKYGCTILAIKHHGDIcLSPAPEDIIREQDCLVIMGHKKDIKRFENE 220
Cdd:PRK09496 160 YEgsPLVGKPLSDLReHFPDIDVRVVAIFRGGRL-IIPRGDTVIEAGDEVYFIGAREHIRAVMSE 223
NDP-sugDHase TIGR03026
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ...
 10-82 1.30e-03

nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.


Pssm-ID: 274399 [Multi-domain]  Cd Length: 409  Bit Score: 39.13  E-value: 1.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A         10 AVIGLGRFGGSIVKELHRMGHEVLAVDINEEKV---NAYASY----ATHAVIANATEENEL-----LSLGIRNFEYVIVA 77
Cdd:TIGR03026   4 AVIGLGYVGLPLAALLADLGHDVTGVDIDQEKVdklNKGKSPiyepGLDELLAKALKAGRLrattdYEEAIRDADVIIIC 83


                  ....*
4J7C_A         78 IGANI 82
Cdd:TIGR03026  84 VPTPL 88
 
Name Accession Description Interval E-value
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 5-206 6.76e-50

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 164.08  E-value: 6.76e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A        5 KNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIG---AN 81
Cdd:COG0569  94 LKMHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEDVLVIVGDATDEEVLEEAGIEDADAVIAATGddeAN 173

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A       82 IQAStlttLLLKELDIPNIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSD-EYSIVELLATR 160
Cdd:COG0569 174 ILAC----LLAKELGVPRIIARANDPEYADLLERLGADVVISPERLAARRIARLLLRPGVLDVLELADgDAEIVEVTVPE 249

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
4J7C_A      161 --KLDSKSIIDLNVRAKYGCTILAIKHHGDIcLSPAPEDIIREQDCLV 206
Cdd:COG0569 250 gsPLVGKTLKELDLRERYGVTVVAIKRGGEV-IIPSGDTVLEAGDELI 296
TrkA_N pfam02254
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ...
 9-124 5.36e-25

TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.


Pssm-ID: 426679 [Multi-domain]  Cd Length: 115  Bit Score: 94.51  E-value: 5.36e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A          9 FAVIGLGRFGGSIVKELHRmGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIGaNIQASTLT 88
Cdd:pfam02254   1 IIIIGYGRVGRSLAEELSE-GGDVVVIDKDEERVEELREEGVPVVVGDATDEEVLEEAGIEEADAVIAATG-DDEANILI 78

                          90       100       110
                  ....*....|....*....|....*....|....*..
4J7C_A         89 TLLLKEL-DIPNIWVKAQNYYHHKVLEKIGADRIIHP 124
Cdd:pfam02254  79 VLLARELnPDKKIIARANDPEHAELLRRLGADHVISP 115
KhtT COG0490
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) ...
 112-220 1.40e-12

K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440256 [Multi-domain]  Cd Length: 140  Bit Score: 62.63  E-value: 1.40e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A      112 VLEKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSDEYSI--VELLATRKLDSKSIIDLNVRAKYGCTILAIKHHGDI 189
Cdd:COG0490  29 GVLGLILRGLLLLELALLLLLLGELLRLLTRLLIELVLLLAIeeVKVPPGSPLVGKTLGELNLRQRTGVTVVAIRRGGEV 108

                        90       100       110
                ....*....|....*....|....*....|.
4J7C_A      190 CLSPAPEDIIREQDCLVIMGHKKDIKRFENE 220
Cdd:COG0490 109 ILSPGPDTVLEAGDTLVVVGTREQLERLEEL 139
Kch COG1226
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];
11-163 6.83e-12

Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];


Pssm-ID: 440839 [Multi-domain]  Cd Length: 279  Bit Score: 63.21  E-value: 6.83e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A       11 VIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGIRNFEYVIVAIgANIQASTLTTL 90
Cdd:COG1226 129 IAGFGRVGQIVARLLRAEGIPFVVIDLDPERVEELRRFGIKVYYGDATRPDVLEAAGIERARALVVAI-DDPEAALRIVE 207

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
4J7C_A       91 LLKEL--DIPnIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSlsdenVLNYIDLSDEYSIVELLATRKLD 163
Cdd:COG1226 208 LARELnpDLK-IIARARDREHAEELRQAGADEVVRETFESALQLARH-----ALEALGVPEEEAARAIQEFRRRD 276
TrkA_C pfam02080
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ...
 153-219 2.87e-09

TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.


Pssm-ID: 460440 [Multi-domain]  Cd Length: 70  Bit Score: 51.84  E-value: 2.87e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
4J7C_A        153 IVELLATRKLDSKSIIDLNVRAKYGCTILAIKHHGDIcLSPAPEDIIREQDCLVIMGHKKDIKRFEN 219
Cdd:pfam02080   3 EVTVPENSPLVGKTLKELNLPERFGVRIVAIRRGGRL-IIPSGDTVLEAGDRLLVIGTPDDLAALRE 68
trkA PRK09496
Trk system potassium transporter TrkA;
11-220 3.79e-09

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 55.90  E-value: 3.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A        11 VIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNaYASYAT--HAVIANATEENELLSLGIRNFEYVIVAIG---ANIQAS 85
Cdd:PRK09496   5 IVGAGQVGYTLAENLSGENNDVTVIDTDEERLR-RLQDRLdvRTVVGNGSSPDVLREAGAEDADLLIAVTDsdeTNMVAC 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A        86 tlttLLLKEL-DIPN--IWVKAQNYYHHKVL---EKIGADRIIHPEKDMGVKIAQSLSDENVLNYIDLSD-EYSIVELLA 158
Cdd:PRK09496  84 ----QIAKSLfGAPTtiARVRNPEYAEYDKLfskEALGIDLLISPELLVAREIARLIEYPGALDVEEFADgRVQLVEVKV 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
4J7C_A       159 TR--KLDSKSIIDLN-VRAKYGCTILAIKHHGDIcLSPAPEDIIREQDCLVIMGHKKDIKRFENE 220
Cdd:PRK09496 160 YEgsPLVGKPLSDLReHFPDIDVRVVAIFRGGRL-IIPRGDTVIEAGDEVYFIGAREHIRAVMSE 223
PRK09599 PRK09599
NADP-dependent phosphogluconate dehydrogenase;
8-53 1.89e-07

NADP-dependent phosphogluconate dehydrogenase;


Pssm-ID: 236582 [Multi-domain]  Cd Length: 301  Bit Score: 50.52  E-value: 1.89e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
4J7C_A         8 QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAV 53
Cdd:PRK09599   2 QLGMIGLGRMGGNMARRLLRGGHEVVGYDRNPEAVEALAEEGATGA 47
YqeC COG1023
6-phosphogluconate dehydrogenase (decarboxylating) [Carbohydrate transport and metabolism];
8-53 6.62e-07

6-phosphogluconate dehydrogenase (decarboxylating) [Carbohydrate transport and metabolism];


Pssm-ID: 440646 [Multi-domain]  Cd Length: 300  Bit Score: 48.93  E-value: 6.62e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
4J7C_A        8 QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAV 53
Cdd:COG1023   2 QIGMIGLGKMGGNMARRLLRHGHEVVGYDRNPEAVAALAAEGATGA 47
AdhP COG1064
D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family [Carbohydrate transport ...
 10-80 2.34e-06

D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family [Carbohydrate transport and metabolism];


Pssm-ID: 440684 [Multi-domain]  Cd Length: 332  Bit Score: 47.41  E-value: 2.34e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
4J7C_A       10 AVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVN-AYASYATHAVIANATEENELLsLGIRNFEYVIVAIGA 80
Cdd:COG1064 167 AVIGAGGLGHLAVQIAKALGAEVIAVDRSPEKLElARELGADHVVNSSDEDPVEAV-RELTGADVVIDTVGA 237
COG3273 COG3273
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only];
136-218 6.29e-06

Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only];


Pssm-ID: 442504 [Multi-domain]  Cd Length: 387  Bit Score: 46.20  E-value: 6.29e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A      136 LSDENVLNYIDLSDEYSIVELLATRK--LDSKSIIDLNVRAKYGCTILAIKHHGDICLSPAPEDIIREQDCLVIMGHKKD 213
Cdd:COG3273 298 LEDHPVVAEAVRESDERIVRVTVPPGspLVGKTLGELKLETETGVRVIAIRRGGGWIYDPDGDTRLRAGDVLIVKGTREG 377


                ....*
4J7C_A      214 IKRFE 218
Cdd:COG3273 378 LERLE 382
YbjL COG2985
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ...
 162-218 2.10e-04

Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];


Pssm-ID: 442224 [Multi-domain]  Cd Length: 543  Bit Score: 41.65  E-value: 2.10e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
4J7C_A      162 LDSKSIIDLNVRAKYGCTILAIKHHGDICLsPAPEDIIREQDCLVIMGHKKDIKRFE 218
Cdd:COG2985 214 LVGKTVAELEALLGTRVVISRIRRGGEIIV-PTPDTVLQEGDIVLVVGTREALEAAE 269
MurD COG0771
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ...
 4-76 8.24e-04

UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440534 [Multi-domain]  Cd Length: 445  Bit Score: 39.68  E-value: 8.24e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
4J7C_A        4 IKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVianATEENELLSLGIRNFEYVIV 76
Cdd:COG0771   2 LKGKKVLVLGLGKSGLAAARLLAKLGAEVTVSDDRPAPELAAAELEAPGV---EVVLGEHPEELLDGADLVVK 71
NDP-sugDHase TIGR03026
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ...
 10-82 1.30e-03

nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.


Pssm-ID: 274399 [Multi-domain]  Cd Length: 409  Bit Score: 39.13  E-value: 1.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4J7C_A         10 AVIGLGRFGGSIVKELHRMGHEVLAVDINEEKV---NAYASY----ATHAVIANATEENEL-----LSLGIRNFEYVIVA 77
Cdd:TIGR03026   4 AVIGLGYVGLPLAALLADLGHDVTGVDIDQEKVdklNKGKSPiyepGLDELLAKALKAGRLrattdYEEAIRDADVIIIC 83


                  ....*
4J7C_A         78 IGANI 82
Cdd:TIGR03026  84 VPTPL 88
NAD_binding_2 pfam03446
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of ...
 8-60 2.52e-03

NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold.


Pssm-ID: 427298 [Multi-domain]  Cd Length: 159  Bit Score: 37.06  E-value: 2.52e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
4J7C_A          8 QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYAsyATHAVIANATEE 60
Cdd:pfam03446   1 KIGFIGLGVMGSPMALNLLKAGYTVTVYNRTPEKVEELV--AAGAIAAASPAE 51
MmsB COG2084
3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport ...
 10-47 2.67e-03

3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport and metabolism];


Pssm-ID: 441687 [Multi-domain]  Cd Length: 285  Bit Score: 37.79  E-value: 2.67e-03
                        10        20        30
                ....*....|....*....|....*....|....*...
4J7C_A       10 AVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYAS 47
Cdd:COG2084   5 GFIGLGAMGAPMARNLLKAGHEVTVWNRTPAKAEALVA 42
YbjL COG2985
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ...
 145-219 4.64e-03

Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];


Pssm-ID: 442224 [Multi-domain]  Cd Length: 543  Bit Score: 37.41  E-value: 4.64e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
4J7C_A      145 IDLSDEYSIVELLATRK-LDSKSIIDLNVRAKYGCTILAIkHHGDICLSPAPEDIIREQDCLVIMGHKKDIKRFEN 219
Cdd:COG2985 280 ELLDSDLDVRRIVVTNKeVAGKTLGELNLRNRFGVVITRV-RRGGVELPATPDTVLQLGDRLTVVGPKEDVERVAK 354
PRK04148 PRK04148
hypothetical protein; Provisional
 3-43 5.60e-03

hypothetical protein; Provisional


Pssm-ID: 235226  Cd Length: 134  Bit Score: 35.75  E-value: 5.60e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
4J7C_A         3 RIKNKQFAVIGLGrFGGSIVKELHRMGHEVLAVDINEEKVN 43
Cdd:PRK04148  14 KGKNKKIVELGIG-FYFKVAKKLKESGFDVIVIDINEKAVE 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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