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Conserved domains on  [gi|312207871|pdb|3L9X|B]
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Chain B, Glutathione-regulated potassium-efflux system protein kefC, linker, ancillary protein kefF

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK03562 super family cl35207
glutathione-regulated potassium-efflux system protein KefC; Provisional
 6-225 1.91e-145

glutathione-regulated potassium-efflux system protein KefC; Provisional


The actual alignment was detected with superfamily member PRK03562:

Pssm-ID: 235131 [Multi-domain]  Cd Length: 621  Bit Score: 427.10  E-value: 1.91e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B         6 RVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQL 85
Cdd:PRK03562 402 RVIIAGFGRFGQIVGRLLLSSGVKMTVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTSLQL 481

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        86 TEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 165
Cdd:PRK03562 482 VELVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKSGRLVLESLGLGPYEARERADRFRRHNLQMVEEMAP 561

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       166 VENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS 225
Cdd:PRK03562 562 HENDTKKRAAVAKQTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS 621
PRK00871 PRK00871
glutathione-regulated potassium-efflux system oxidoreductase KefF;
238-413 3.33e-138

glutathione-regulated potassium-efflux system oxidoreductase KefF;


:

Pssm-ID: 234852  Cd Length: 176  Bit Score: 392.23  E-value: 3.33e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       238 MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDK 317
Cdd:PRK00871   1 MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       318 VFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA 397
Cdd:PRK00871  81 VLSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATALYCGLNWLPPFAMHCTFICDDETLEGQA 160

                        170
                 ....*....|....*.
3L9X_B       398 RHYKQRLLEWQEAHHG 413
Cdd:PRK00871 161 RHYKQRLLEWQEAHHG 176
 
Name Accession Description Interval E-value
PRK03562 PRK03562
glutathione-regulated potassium-efflux system protein KefC; Provisional
 6-225 1.91e-145

glutathione-regulated potassium-efflux system protein KefC; Provisional


Pssm-ID: 235131 [Multi-domain]  Cd Length: 621  Bit Score: 427.10  E-value: 1.91e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B         6 RVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQL 85
Cdd:PRK03562 402 RVIIAGFGRFGQIVGRLLLSSGVKMTVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTSLQL 481

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        86 TEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 165
Cdd:PRK03562 482 VELVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKSGRLVLESLGLGPYEARERADRFRRHNLQMVEEMAP 561

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       166 VENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS 225
Cdd:PRK03562 562 HENDTKKRAAVAKQTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS 621
PRK00871 PRK00871
glutathione-regulated potassium-efflux system oxidoreductase KefF;
238-413 3.33e-138

glutathione-regulated potassium-efflux system oxidoreductase KefF;


Pssm-ID: 234852  Cd Length: 176  Bit Score: 392.23  E-value: 3.33e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       238 MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDK 317
Cdd:PRK00871   1 MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       318 VFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA 397
Cdd:PRK00871  81 VLSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATALYCGLNWLPPFAMHCTFICDDETLEGQA 160

                        170
                 ....*....|....*.
3L9X_B       398 RHYKQRLLEWQEAHHG 413
Cdd:PRK00871 161 RHYKQRLLEWQEAHHG 176
Kch COG1226
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];
6-159 1.90e-65

Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];


Pssm-ID: 440839 [Multi-domain]  Cd Length: 279  Bit Score: 210.36  E-value: 1.90e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        6 RVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQL 85
Cdd:COG1226 126 HVIIAGFGRVGQIVARLLRAEGIPFVVIDLDPERVEELRRFGIKVYYGDATRPDVLEAAGIERARALVVAIDDPEAALRI 205

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
3L9X_B       86 TEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQM 159
Cdd:COG1226 206 VELARELNPDLKIIARARDREHAEELRQAGADEVVRETFESALQLARHALEALGVPEEEAARAIQEFRRRDYER 279
MdaB COG2249
Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction ...
 239-408 3.92e-53

Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only];


Pssm-ID: 441850 [Multi-domain]  Cd Length: 190  Bit Score: 175.41  E-value: 3.92e-53
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B      239 ILIIYAHPYPhhSHANKRMLEQAR-TLE----GVEIRSLYQL-YP------------DFNIDIAAEQEALSRADLIVWQH 300
Cdd:COG2249   2 ILIIYAHPDP--SSFNAALAEAAAeGLEaaghEVTVHDLYAEgFDpvlsaadfyrdgPLPIDVAAEQELLLWADHLVFQF 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B      301 PMQWYSIPPLLKLWIDKVFSHGWAYGHG----GTALHGKHLLWAVTTGGGESHFEIGAHPGF--DVLsqpLQATAIYCGL 374
Cdd:COG2249  80 PLWWYSMPALLKGWIDRVLTPGFAYGYGggypGGLLKGKKALLVVTTGGPEEAYSRLGYGGPieELL---FRGTLGYCGM 156

                       170       180       190
                ....*....|....*....|....*....|....
3L9X_B      375 NWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQ 408
Cdd:COG2249 157 KVLPPFVLYGVDRSSDEERAAWLERVRELLAALA 190
Flavodoxin_2 pfam02525
Flavodoxin-like fold; This family consists of a domain with a flavodoxin-like fold. The family ...
 239-404 4.53e-46

Flavodoxin-like fold; This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.


Pssm-ID: 426816 [Multi-domain]  Cd Length: 193  Bit Score: 157.11  E-value: 4.53e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        239 ILIIYAHPYPHH--SHANKRMLEQARTLEG-VEIRSLYQL--------------YPDFNIDIAAEQEALSRADLIVWQHP 301
Cdd:pfam02525   3 ILIINAHPRPGSfsSRLADALVEALKAAGHeVTVRDLYALflpvldaedladltYPQGAADVESEQEELLAADVIVFQFP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        302 MQWYSIPPLLKLWIDKVFSHGWAY-----GHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDV--LSQPLQATAIYCGL 374
Cdd:pfam02525  83 LYWFSVPALLKGWIDRVLRAGFAFkyeegGPGGGGLLGKKVLVIVTTGGPEYAYGKGGYNGFSLdeLLPYLRGILGFCGI 162

                         170       180       190
                  ....*....|....*....|....*....|.
3L9X_B        375 NWLPPFAMHCTFICDDE-TLEGQARHYKQRL 404
Cdd:pfam02525 163 TDLPPFAVEGTAGPEDEaALAEALERYEERL 193
TrkA_N pfam02254
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ...
 7-116 3.38e-33

TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.


Pssm-ID: 426679 [Multi-domain]  Cd Length: 115  Bit Score: 120.71  E-value: 3.38e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B          7 VIIAGFGRFGQITGRLLLSSGvKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLT 86
Cdd:pfam02254   1 IIIIGYGRVGRSLAEELSEGG-DVVVIDKDEERVEELREEGVPVVVGDATDEEVLEEAGIEEADAVIAATGDDEANILIV 79

                          90       100       110
                  ....*....|....*....|....*....|
3L9X_B         87 EMVKEHFPHLQIIARARDVDHYIRLRQAGV 116
Cdd:pfam02254  80 LLARELNPDKKIIARANDPEHAELLRRLGA 109
 
Name Accession Description Interval E-value
PRK03562 PRK03562
glutathione-regulated potassium-efflux system protein KefC; Provisional
 6-225 1.91e-145

glutathione-regulated potassium-efflux system protein KefC; Provisional


Pssm-ID: 235131 [Multi-domain]  Cd Length: 621  Bit Score: 427.10  E-value: 1.91e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B         6 RVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQL 85
Cdd:PRK03562 402 RVIIAGFGRFGQIVGRLLLSSGVKMTVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTSLQL 481

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        86 TEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 165
Cdd:PRK03562 482 VELVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKSGRLVLESLGLGPYEARERADRFRRHNLQMVEEMAP 561

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       166 VENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS 225
Cdd:PRK03562 562 HENDTKKRAAVAKQTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS 621
PRK00871 PRK00871
glutathione-regulated potassium-efflux system oxidoreductase KefF;
238-413 3.33e-138

glutathione-regulated potassium-efflux system oxidoreductase KefF;


Pssm-ID: 234852  Cd Length: 176  Bit Score: 392.23  E-value: 3.33e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       238 MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDK 317
Cdd:PRK00871   1 MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       318 VFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA 397
Cdd:PRK00871  81 VLSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATALYCGLNWLPPFAMHCTFICDDETLEGQA 160

                        170
                 ....*....|....*.
3L9X_B       398 RHYKQRLLEWQEAHHG 413
Cdd:PRK00871 161 RHYKQRLLEWQEAHHG 176
Kch COG1226
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];
6-159 1.90e-65

Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];


Pssm-ID: 440839 [Multi-domain]  Cd Length: 279  Bit Score: 210.36  E-value: 1.90e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        6 RVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQL 85
Cdd:COG1226 126 HVIIAGFGRVGQIVARLLRAEGIPFVVIDLDPERVEELRRFGIKVYYGDATRPDVLEAAGIERARALVVAIDDPEAALRI 205

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
3L9X_B       86 TEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQM 159
Cdd:COG1226 206 VELARELNPDLKIIARARDREHAEELRQAGADEVVRETFESALQLARHALEALGVPEEEAARAIQEFRRRDYER 279
PRK03659 PRK03659
glutathione-regulated potassium-efflux system protein KefB; Provisional
 6-204 1.87e-54

glutathione-regulated potassium-efflux system protein KefB; Provisional


Pssm-ID: 179625 [Multi-domain]  Cd Length: 601  Bit Score: 190.24  E-value: 1.87e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B         6 RVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQL 85
Cdd:PRK03659 402 QVIIVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQLELLRAAGAEKAEAIVITCNEPEDTMKI 481

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        86 TEMVKEHFPHLQIIARARD-VDHYiRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMA 164
Cdd:PRK03659 482 VELCQQHFPHLHILARARGrVEAH-ELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQQHFRRLDMRMLRELM 560

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
3L9X_B       165 MVENDTKARAAVYKRTSAMLSEIITEDREHLSLiQRHGWQ 204
Cdd:PRK03659 561 PQHNGDVVQISRAKEARRELEEIFQREMQQERR-QLDGWD 599
MdaB COG2249
Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction ...
 239-408 3.92e-53

Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only];


Pssm-ID: 441850 [Multi-domain]  Cd Length: 190  Bit Score: 175.41  E-value: 3.92e-53
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B      239 ILIIYAHPYPhhSHANKRMLEQAR-TLE----GVEIRSLYQL-YP------------DFNIDIAAEQEALSRADLIVWQH 300
Cdd:COG2249   2 ILIIYAHPDP--SSFNAALAEAAAeGLEaaghEVTVHDLYAEgFDpvlsaadfyrdgPLPIDVAAEQELLLWADHLVFQF 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B      301 PMQWYSIPPLLKLWIDKVFSHGWAYGHG----GTALHGKHLLWAVTTGGGESHFEIGAHPGF--DVLsqpLQATAIYCGL 374
Cdd:COG2249  80 PLWWYSMPALLKGWIDRVLTPGFAYGYGggypGGLLKGKKALLVVTTGGPEEAYSRLGYGGPieELL---FRGTLGYCGM 156

                       170       180       190
                ....*....|....*....|....*....|....
3L9X_B      375 NWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQ 408
Cdd:COG2249 157 KVLPPFVLYGVDRSSDEERAAWLERVRELLAALA 190
PRK04930 PRK04930
glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional
 239-404 1.41e-48

glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional


Pssm-ID: 179895 [Multi-domain]  Cd Length: 184  Bit Score: 163.25  E-value: 1.41e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       239 ILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKV 318
Cdd:PRK04930   8 VLLLYAHPESQDSVANRVLLKPAQQLEHVTVHDLYAHYPDFFIDIPHEQALLREHDVIVFQHPLYTYSCPALLKEWLDRV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       319 FSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGA---HPGFDVLsQPLQATAIYCGLNWLPPFAMHCTFICDDETLEG 395
Cdd:PRK04930  88 LSRGFASGPGGNALAGKYWRSVITTGEPESAYRYDGynrYPMSDIL-RPFELTAAMCRMHWLSPIIIYWARRQSPEELAS 166


                 ....*....
3L9X_B       396 QARHYKQRL 404
Cdd:PRK04930 167 HARAYGDWL 175
Flavodoxin_2 pfam02525
Flavodoxin-like fold; This family consists of a domain with a flavodoxin-like fold. The family ...
 239-404 4.53e-46

Flavodoxin-like fold; This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.


Pssm-ID: 426816 [Multi-domain]  Cd Length: 193  Bit Score: 157.11  E-value: 4.53e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        239 ILIIYAHPYPHH--SHANKRMLEQARTLEG-VEIRSLYQL--------------YPDFNIDIAAEQEALSRADLIVWQHP 301
Cdd:pfam02525   3 ILIINAHPRPGSfsSRLADALVEALKAAGHeVTVRDLYALflpvldaedladltYPQGAADVESEQEELLAADVIVFQFP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        302 MQWYSIPPLLKLWIDKVFSHGWAY-----GHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDV--LSQPLQATAIYCGL 374
Cdd:pfam02525  83 LYWFSVPALLKGWIDRVLRAGFAFkyeegGPGGGGLLGKKVLVIVTTGGPEYAYGKGGYNGFSLdeLLPYLRGILGFCGI 162

                         170       180       190
                  ....*....|....*....|....*....|.
3L9X_B        375 NWLPPFAMHCTFICDDE-TLEGQARHYKQRL 404
Cdd:pfam02525 163 TDLPPFAVEGTAGPEDEaALAEALERYEERL 193
TrkA_N pfam02254
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ...
 7-116 3.38e-33

TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.


Pssm-ID: 426679 [Multi-domain]  Cd Length: 115  Bit Score: 120.71  E-value: 3.38e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B          7 VIIAGFGRFGQITGRLLLSSGvKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLT 86
Cdd:pfam02254   1 IIIIGYGRVGRSLAEELSEGG-DVVVIDKDEERVEELREEGVPVVVGDATDEEVLEEAGIEEADAVIAATGDDEANILIV 79

                          90       100       110
                  ....*....|....*....|....*....|
3L9X_B         87 EMVKEHFPHLQIIARARDVDHYIRLRQAGV 116
Cdd:pfam02254  80 LLARELNPDKKIIARANDPEHAELLRRLGA 109
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 5-147 1.51e-26

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 107.85  E-value: 1.51e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B        5 MRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQ 84
Cdd:COG0569  96 MHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEDVLVIVGDATDEEVLEEAGIEDADAVIAATGDDEANIL 175

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       85 LTEMVKEHFPhLQIIARARDVDHYIRLRQAGVEK---PERET---FEGALKTGR-LALESLGLGPYEARE 147
Cdd:COG0569 176 ACLLAKELGV-PRIIARANDPEYADLLERLGADVvisPERLAarrIARLLLRPGvLDVLELADGDAEIVE 244
PRK09739 PRK09739
NAD(P)H oxidoreductase;
239-406 1.82e-12

NAD(P)H oxidoreductase;


Pssm-ID: 236620 [Multi-domain]  Cd Length: 199  Bit Score: 65.88  E-value: 1.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       239 ILIIYAHPYPHH--SHANKRMLEQARTLeGVEIRSLyQLY-------------PDFNI-------DIAAEQEALSRADLI 296
Cdd:PRK09739   6 IYLVWAHPRHDSltAKVAEAIHQRAQER-GHQVEEL-DLYrsgfdpvltpedePDWKNpdkryspEVHQLYSELLEHDAL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B       297 VWQHPMQWYSIPPLLKLWIDKVFSHGWAYGhGGTALHGKHLLWAVTTGGGESHFEigaHPGFD-VLSQPLQA-TAIYCGL 374
Cdd:PRK09739  84 VFVFPLWWYSFPAMLKGYIDRVWNNGLAYG-DGHKLPFNKVRWVALVGGSKESFV---KRGWEkNMSDYLNVgMASYLGI 159

                        170       180       190
                 ....*....|....*....|....*....|....*
3L9X_B       375 NwlppfAMHCTFICD---DETLEGQARHYkQRLLE 406
Cdd:PRK09739 160 E-----DSDVTFLYNtlvFDGEELHASHY-QSLLS 188
trkA PRK09496
Trk system potassium transporter TrkA;
5-123 2.98e-07

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 52.43  E-value: 2.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B         5 MRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLR-KFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNL 83
Cdd:PRK09496   1 MKIIIVGAGQVGYTLAENLSGENNDVTVIDTDEERLRRLQdRLDVRTVVGNGSSPDVLREAGAEDADLLIAVTDSDETNM 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
3L9X_B        84 QLTEMVKEHFPHLQIIARARDVDhYIRLRQAGVEK---------PERET 123
Cdd:PRK09496  81 VACQIAKSLFGAPTTIARVRNPE-YAEYDKLFSKEalgidllisPELLV 128
PRK10669 PRK10669
putative cation:proton antiport protein; Provisional
 8-123 7.10e-07

putative cation:proton antiport protein; Provisional


Pssm-ID: 182633 [Multi-domain]  Cd Length: 558  Bit Score: 51.25  E-value: 7.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B         8 IIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTE 87
Cdd:PRK10669 421 LLVGYGRVGSLLGEKLLAAGIPLVVIETSRTRVDELRERGIRAVLGNAANEEIMQLAHLDCARWLLLTIPNGYEAGEIVA 500

                         90       100       110
                 ....*....|....*....|....*....|....*....
3L9X_B        88 MVKEHFPHLQIIARARDVDH--YIRLRQAG-VEKPERET 123
Cdd:PRK10669 501 SAREKRPDIEIIARAHYDDEvaYITERGANqVVMGEREI 539
trkA PRK09496
Trk system potassium transporter TrkA;
6-83 3.36e-06

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 48.97  E-value: 3.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B         6 RVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIE--------TLrkfgmkVFYGDATRMDLLESAGAAKAEVLINAID 77
Cdd:PRK09496 233 RVMIVGGGNIGYYLAKLLEKEGYSVKLIERDPERAEelaeelpnTL------VLHGDGTDQELLEEEGIDEADAFIALTN 306


                 ....*.
3L9X_B        78 DPQTNL 83
Cdd:PRK09496 307 DDEANI 312
WrbA COG0655
Multimeric flavodoxin WrbA, includes NAD(P)H:quinone oxidoreductase [Energy production and ...
 239-406 5.39e-05

Multimeric flavodoxin WrbA, includes NAD(P)H:quinone oxidoreductase [Energy production and conversion];


Pssm-ID: 440420 [Multi-domain]  Cd Length: 181  Bit Score: 43.76  E-value: 5.39e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B      239 ILIIYAhpYPHHSHANKRMLEQArtLEG-------VEIRSLYQLYPDFNI------------DIAAEQEALSRADLIVWQ 299
Cdd:COG0655   2 ILVING--SPRKNGNTAALAEAV--AEGaeeagaeVELIRLADLDIKPCIgcggtgkcvikdDMNAIYEKLLEADGIIFG 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3L9X_B      300 HPMQWYSIPPLLKLWIDKVFshgwAYGHGGTALHGKhLLWAVTTGGGEshfeiGAHPGFDVLSQPLQataiYCGLNWLPP 379
Cdd:COG0655  78 SPTYFGNMSAQLKAFIDRLY----ALWAKGKLLKGK-VGAVFTTGGHG-----GAEATLLSLNTFLL----HHGMIVVGL 143

                       170       180       190
                ....*....|....*....|....*....|...
3L9X_B      380 F---AMHCTF---ICDDETLEgQARHYKQRLLE 406
Cdd:COG0655 144 PpygAVGGGGpgdVLDEEGLA-TARELGKRLAE 175
FMN_red pfam03358
NADPH-dependent FMN reductase;
282-349 1.19e-04

NADPH-dependent FMN reductase;


Pssm-ID: 427259 [Multi-domain]  Cd Length: 152  Bit Score: 42.23  E-value: 1.19e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3L9X_B        282 DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFshgwaYGHGGTALHGKhLLWAVTTGGGESH 349
Cdd:pfam03358  59 DVQELREKIAAADAIIIVTPEYNGSVSGLLKNAIDWLS-----RLRGGKELRGK-PVAIVSTGGGRSG 120
PRK08306 PRK08306
dipicolinate synthase subunit DpsA;
3-76 6.02e-03

dipicolinate synthase subunit DpsA;


Pssm-ID: 181371 [Multi-domain]  Cd Length: 296  Bit Score: 38.28  E-value: 6.02e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
3L9X_B         3 HGMRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYgdatrMDLLESAgAAKAEVLINAI 76
Cdd:PRK08306 151 HGSNVLVLGFGRTGMTLARTLKALGANVTVGARKSAHLARITEMGLSPFH-----LSELAEE-VGKIDIIFNTI 218
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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