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Conserved domains on  [gi|159162127|pdb|1BQZ|A]
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Chain A, DNAJ

Protein Classification

molecular chaperone DnaJ( domain architecture ID 1000952)

molecular chaperone DnaJ, part of the DnaK-DnaJ-GrpE system, prevents the aggregation of unfolded substrate and acts primarily by stimulating the ATPase activity of Hsp70

CATH:  2.10.230.10
Gene Ontology:  GO:0051082|GO:0005524|GO:0009408|GO:0006457
PubMed:  8016869|15063739|29290615
SCOP:  4003813|4002149

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10767 super family cl35946
chaperone protein DnaJ; Provisional
 1-77 1.26e-59

chaperone protein DnaJ; Provisional


The actual alignment was detected with superfamily member PRK10767:

Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 184.96  E-value: 1.26e-59
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK10767   2 AKRDYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKEAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAAFEQGG 78
 
Name Accession Description Interval E-value
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 1-77 1.26e-59

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 184.96  E-value: 1.26e-59
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK10767   2 AKRDYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKEAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAAFEQGG 78
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 4-77 2.41e-45

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 147.75  E-value: 2.41e-45
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1BQZ_A          4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNK-DKEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGG 73
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 4-66 1.54e-32

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 106.79  E-value: 1.54e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
1BQZ_A         4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYD 66
Cdd:pfam00226  1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
1-70 4.22e-32

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 114.92  E-value: 4.22e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNqGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGH 70
Cdd:NF037946   3 EKRDYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRN-KAPDAAEIFAEINEAYEVLSNPEKRANYDKYGH 71
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 4-74 5.36e-31

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 105.55  E-value: 5.36e-31
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1BQZ_A        4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFE 74
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAEL 71
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 4-58 1.81e-24

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 86.06  E-value: 1.81e-24
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....*
1BQZ_A       4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTD 58
Cdd:cd06257  1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAEEKFKEINEAYEVLSD 55
DnaJ smart00271
DnaJ molecular chaperone homology domain;
3-61 2.06e-23

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 83.82  E-value: 2.06e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A          3 QDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDK-EAEAKFKEIKEAYEVLTDSQK 61
Cdd:smart00271  1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKeEAEEKFKEINEAYEVLSDPEK 60
 
Name Accession Description Interval E-value
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 1-77 1.26e-59

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 184.96  E-value: 1.26e-59
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK10767   2 AKRDYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKEAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAAFEQGG 78
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 4-77 2.41e-45

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 147.75  E-value: 2.41e-45
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1BQZ_A          4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNK-DKEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGG 73
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 1-77 1.28e-40

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 136.47  E-value: 1.28e-40
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14277   3 AKKDYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGDKEAEQKFKEINEAYEILSDPQKRAQYDQFGHAAFDPGG 79
PRK14297 PRK14297
molecular chaperone DnaJ;
1-77 5.28e-38

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 129.52  E-value: 5.28e-38
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14297   2 ASKDYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNKEAEEKFKEINEAYQVLSDPQKKAQYDQFGTADFNGAG 78
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 2-77 1.82e-35

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 122.57  E-value: 1.82e-35
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         2 KQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14294   3 KRDYYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPGDKEAEELFKEAAEAYEVLSDPKKRGIYDQYGHEGLSGTG 78
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 1-77 1.72e-34

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 120.26  E-value: 1.72e-34
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14291   1 AKKDYYEILGVSRNATQEEIKKAYRRLARKYHPDFNK-NPEAEEKFKEINEAYQVLSDPEKRKLYDQFGHAAFSGSG 76
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 2-71 1.81e-33

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 117.99  E-value: 1.81e-33
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A         2 KQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHA 71
Cdd:PRK14281   2 KRDYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDNKEAEEHFKEVNEAYEVLSNDDKRRRYDQFGHA 71
PRK14289 PRK14289
molecular chaperone DnaJ;
1-71 1.98e-33

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 117.62  E-value: 1.98e-33
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHA 71
Cdd:PRK14289   3 EKRDYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGDKEAEEKFKEAAEAYDVLSDPDKRSRYDQFGHA 73
PRK14280 PRK14280
molecular chaperone DnaJ;
1-76 3.15e-33

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 116.74  E-value: 3.15e-33
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQG 76
Cdd:PRK14280   2 AKRDYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINK-EEGADEKFKEISEAYEVLSDDQKRAQYDQFGHAGPNQG 76
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 2-77 3.33e-33

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 116.77  E-value: 3.33e-33
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         2 KQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14301   3 QRDYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDNPEAEQKFKEAAEAYEVLRDAEKRARYDRFGHAGVNGNG 78
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 4-66 1.54e-32

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 106.79  E-value: 1.54e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
1BQZ_A         4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYD 66
Cdd:pfam00226  1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 1-76 1.93e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 114.80  E-value: 1.93e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQG 76
Cdd:PRK14276   2 NNTEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINK-EPGAEEKYKEVQEAYETLSDPQKRAAYDQYGAAGANGG 76
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
1-70 4.22e-32

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 114.92  E-value: 4.22e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNqGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGH 70
Cdd:NF037946   3 EKRDYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRN-KAPDAAEIFAEINEAYEVLSNPEKRANYDKYGH 71
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 2-71 5.87e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 113.41  E-value: 5.87e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A         2 KQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHA 71
Cdd:PRK14298   4 TRDYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNK-EPDAEEKFKEISEAYAVLSDAEKRAQYDRFGHA 72
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 2-77 6.64e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 113.16  E-value: 6.64e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         2 KQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14285   2 KRDYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGNKEAESIFKEATEAYEVLIDDNKRAQYDRFGHTAFEGGG 77
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 1-74 1.91e-31

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 112.23  E-value: 1.91e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFE 74
Cdd:PRK14283   3 EKRDYYEVLGVDRNADKKEIKKAYRKLARKYHPDVSE-EEGAEEKFKEISEAYAVLSDDEKRQRYDQFGHAGMD 75
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 4-74 5.36e-31

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 105.55  E-value: 5.36e-31
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1BQZ_A        4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFE 74
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAEL 71
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 1-77 2.31e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 109.31  E-value: 2.31e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14286   2 SERSYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNKESEEKFKEATEAYEILRDPKKRQAYDQFGKAGVNAGA 78
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 1-70 2.62e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 109.11  E-value: 2.62e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGD-KEAEAKFKEIKEAYEVLTDSQKRAAYDQYGH 70
Cdd:PRK14282   2 EKKDYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENrKEAEQKFKEIQEAYEVLSDPQKRAMYDRFGY 72
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 4-69 4.51e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 108.78  E-value: 4.51e-30
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYG 69
Cdd:PRK14284   2 DYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDAEAEKRFKEVSEAYEVLSDAQKRESYDRYG 67
PRK14295 PRK14295
molecular chaperone DnaJ;
2-77 1.84e-29

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 107.24  E-value: 1.84e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A         2 KQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQ----YGHAAFEQGG 77
Cdd:PRK14295   8 EKDYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKGDAKAEERFKEISEAYDVLSDEKKRKEYDEarslFGNGGFRPGP 87
PRK14293 PRK14293
molecular chaperone DnaJ;
4-71 2.65e-29

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 106.23  E-value: 2.65e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A         4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNqgdKE--AEAKFKEIKEAYEVLTDSQKRAAYDQYGHA 71
Cdd:PRK14293   4 DYYEILGVSRDADKDELKRAYRRLARKYHPDVN---KEpgAEDRFKEINRAYEVLSDPETRARYDQFGEA 70
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 1-74 2.87e-28

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 103.49  E-value: 2.87e-28
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFE 74
Cdd:PRK14296   2 KKKDYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLNK-SPDAHDKMVEINEAADVLLDKDKRKQYDQFGHAAFD 74
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 1-76 3.29e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 99.63  E-value: 3.29e-27
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQG 76
Cdd:PRK14299   2 AYKDYYAILGVPKNASQDEIKKAFKKLARKYHPDVNK-SPGAEEKFKEINEAYTVLSDPEKRRIYDTYGTTAASAG 76
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 4-77 9.76e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 99.74  E-value: 9.76e-27
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1BQZ_A         4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNqGDKEAEAKFKEIKEAYEVLTDSQKRAAYDqYGHAAFEQGG 77
Cdd:PRK14278   4 DYYGLLGVSRNASDAEIKRAYRKLARELHPDVN-PDEEAQEKFKEISVAYEVLSDPEKRRIVD-LGGDPLESAG 75
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 3-74 1.32e-26

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 99.32  E-value: 1.32e-26
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
1BQZ_A         3 QDYYEILGVSKTAEEREIRKAYKRLAMKYHPDrNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFE 74
Cdd:PRK14300   3 QDYYQILGVSKTASQADLKKAYLKLAKQYHPD-TTDAKDAEKKFKEINAAYDVLKDEQKRAAYDRFGHDAFQ 73
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 3-77 9.16e-26

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 96.92  E-value: 9.16e-26
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         3 QDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDK-EAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14290   3 KDYYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNKaEAEEKFKEISEAYEVLSDPQKRRQYDQTGTVDFGAGG 78
PRK14279 PRK14279
molecular chaperone DnaJ;
1-77 1.03e-25

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 97.11  E-value: 1.03e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYgHAAFEQGG 77
Cdd:PRK14279   7 VEKDFYKELGVSSDASAEEIKKAYRKLARELHPDANPGDPAAEERFKAVSEAHDVLSDPAKRKEYDET-RRLFAGGG 82
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 1-76 4.44e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 95.08  E-value: 4.44e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQG 76
Cdd:PRK14287   2 SKRDYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNK-APDAEDKFKEVKEAYDTLSDPQKKAHYDQFGHTDPNQG 76
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 4-71 8.94e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 94.19  E-value: 8.94e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
1BQZ_A         4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHA 71
Cdd:PRK14292   3 DYYELLGVSRTASADEIKSAYRKLALKYHPDRNK-EKGAAEKFAQINEAYAVLSDAEKRAHYDRFGTA 69
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 4-58 1.81e-24

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 86.06  E-value: 1.81e-24
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....*
1BQZ_A       4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTD 58
Cdd:cd06257  1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAEEKFKEINEAYEVLSD 55
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 4-64 3.28e-24

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 85.82  E-value: 3.28e-24
                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|.
1BQZ_A       4 DYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAA 64
Cdd:COG5407  1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDPKAEERFKEINEAYELLSDAEKRAR 61
termin_org_DnaJ TIGR03835
terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ ...
 2-70 9.93e-24

terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ homolog and probable assembly protein of the Mycoplasma terminal organelle. The terminal organelle is involved in both cytadherence and gliding motility. [Cellular processes, Chemotaxis and motility]


Pssm-ID: 274808 [Multi-domain]  Cd Length: 871  Bit Score: 92.57  E-value: 9.93e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
1BQZ_A          2 KQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGH 70
Cdd:TIGR03835   1 KRDYYEVLGIDRDADEQEIKKAFRKLAKKYHPDRNK-APDAASIFAEINEANDVLSNPKKRANYDKYGH 68
DnaJ smart00271
DnaJ molecular chaperone homology domain;
3-61 2.06e-23

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 83.82  E-value: 2.06e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A          3 QDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDK-EAEAKFKEIKEAYEVLTDSQK 61
Cdd:smart00271  1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKeEAEEKFKEINEAYEVLSDPEK 60
PRK10266 PRK10266
curved DNA-binding protein;
3-67 2.04e-22

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 87.18  E-value: 2.04e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
1BQZ_A         3 QDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQgDKEAEAKFKEIKEAYEVLTDSQKRAAYDQ 67
Cdd:PRK10266   4 KDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSK-EPDAEARFKEVAEAWEVLSDEQRRAEYDQ 67
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
3-67 6.12e-22

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 80.92  E-value: 6.12e-22
                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|....*.
1BQZ_A       3 QDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKE-AEAKFKEIKEAYEVLTDSQKRAAYDQ 67
Cdd:COG2214  5 KDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKAlAEELFQRLNEAYEVLSDPERRAEYDR 70
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 5-77 2.60e-21

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 85.26  E-value: 2.60e-21
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
1BQZ_A         5 YYEILGVSKTAEEREIRKAYKRLAMKYHPDRNqGDKEaeaKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PTZ00037  30 LYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKG-GDPE---KFKEISRAYEVLSDPEKRKIYDEYGEEGLEGGE 98
PRK14288 PRK14288
molecular chaperone DnaJ;
5-77 2.40e-20

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 82.43  E-value: 2.40e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
1BQZ_A         5 YYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGG 77
Cdd:PRK14288   5 YYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQAG 77
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
3-64 6.31e-12

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 54.80  E-value: 6.31e-12
                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|....*...
1BQZ_A       3 QDYYEILGVSKTAEEREIRKAYKRLAMKYHPDR---NQGDKE---AEAKFKEIKEAYEVLTDSQKRAA 64
Cdd:COG1076  4 DDAFELLGLPPDADDAELKRAYRKLQREHHPDRlaaGLPEEEqrlALQKAAAINEAYETLKDPRGIDL 71
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 5-75 9.63e-12

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 58.26  E-value: 9.63e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1BQZ_A          5 YYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDkEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQ 75
Cdd:PTZ00341  575 FYDILGVGVNADMKEISERYFKLAENYYPPKRSGN-EGFHKFKKINEAYQILGDIDKKKMYNKFGYDGIKG 644
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 2-66 1.02e-07

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 46.95  E-value: 1.02e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A        2 KQDYYEILGVSK---TAEEREIRKAYKRLAMKYHPDRNQ--GDKEAEAKFKEIKEAYEVLTDSQKRAAYD 66
Cdd:COG5269  42 KVDLYALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAagGNKGCDEFFKLIQKAREVLGDRKLRLQYD 111
djlA PRK09430
co-chaperone DjlA;
3-56 4.67e-07

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 44.80  E-value: 4.67e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
1BQZ_A         3 QDYYEILGVSKTAEEREIRKAYKRLAMKYHPDR--NQGDKE-----AEAKFKEIKEAYEVL 56
Cdd:PRK09430 200 EDAYKVLGVSESDDDQEIKRAYRKLMSEHHPDKlvAKGLPPemmemAKEKAQEIQAAYELI 260
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
 1-51 1.02e-06

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 42.53  E-value: 1.02e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
1BQZ_A         1 AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDrNQGDKEAEAKFKEIKE 51
Cdd:PTZ00100  63 SKSEAYKILNISPTASKERIREAHKQLMLRNHPD-NGGSTYIASKVNEAKD 112
PHA03102 PHA03102
Small T antigen; Reviewed
 7-69 3.00e-05

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 39.27  E-value: 3.00e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
1BQZ_A         7 EILGVSKTAEERE--IRKAYKRLAMKYHPDRNqGDkeaEAKFKEIKEAYEVLTDSQKRAAYDQYG 69
Cdd:PHA03102   9 DLLGLPRSAWGNLplMRKAYLRKCLEFHPDKG-GD---EEKMKELNTLYKKFRESVKSLRDLDGE 69
PHA02624 PHA02624
large T antigen; Provisional
 7-75 2.88e-04

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 37.27  E-value: 2.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BQZ_A         7 EILGVSKTAEERE--IRKAYKRLAMKYHPDRNqGDkeaEAKFKEIKEAYEVLTDSQKRA-----AYD-----QYGHAAFE 74
Cdd:PHA02624  15 DLLGLPMAAWGNLplMRKAYLRKCKEYHPDKG-GD---EEKMKRLNSLYKKLQEGVKSArqsfgTQDsseipTYGTPEWE 90


                 .
1BQZ_A        75 Q 75
Cdd:PHA02624  91 Q 91
hscB PRK01356
co-chaperone HscB; Provisional
 3-65 4.16e-04

co-chaperone HscB; Provisional


Pssm-ID: 167217 [Multi-domain]  Cd Length: 166  Bit Score: 36.39  E-value: 4.16e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
1BQZ_A         3 QDYYEILGVSKT--AEEREIRKAYKRLAMKYHPDRNQGDKEAEAKF---KEIKEAYEVLTDSQKRAAY 65
Cdd:PRK01356   2 QNYFQLLGLPQEynIDLKILEKQYFAMQVKYHPDKAKTLQEKEQNLiiaSELNNAYSTLKDALKRAEY 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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