?cl09653: Btz Superfamily (this model, PSSM-Id:415684 is obsolete and has been replaced by 447763)
CASC3/Barentsz eIF4AIII binding This domain is found on CASC3 (cancer susceptibility candidate gene 3 protein) which is also known as Barentsz (Btz). CASC3 is a component of the EJC (exon junction complex) which is a complex that is involved in post-transcriptional regulation of mRNA in metazoa. The complex is formed by the association of four proteins (eIF4AIII, Barentsz, Mago, and Y14), mRNA, and ATP. This domain wraps around eIF4AIII and stacks against the 5' nucleotide. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",