5FGK,4F6S,5ICP,5XQX


Conserved Protein Domain Family
CYCLIN_CCNC_rpt2
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cd20514: CYCLIN_CCNC_rpt2 
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second cyclin box found in cyclin-C (CCNC) and similar proteins
CCNC, also termed CycC, or SRB11, is a component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. It mediates stress-induced mitochondrial fission and apoptosis. CCNC contains two cyclin boxes. This model corresponds to the second one. The cyclin box is a protein binding domain.
Links
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Statistics
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PSSM-Id: 410218
Aligned: 32 rows
Threshold Bit Score: 92.6827
Created: 12-Apr-2019
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5FGK_B       156 HPYRPLLQYVQDMGq---eDMLLPLAWRIVNDTYRTDLCLlYPPFMIALACLHVACVVQq---------kDARQWFAELS 223 human
CBY23085     174 HPYRPLLQFLQDLNikesdDRLSLMAWRVLNDSYRSDVMLqYPPYMIALAALHMSGIQLnymerqvhgrpKLSDWFAELS 253 Oikopleura dioica
XP_002682418 171 HSHTSLMTYVKDAEl---dKSLYQICWNIVNDSFYSEVVLkYPPYLVSLTSIYMTSILKndeen-ninkeKARKWFDQLY 246 Naegleria grube...
KJE91914     124 HPYRPLTHYCHGLDd----KQLLTTAWFILNDSYRTDLCLqYPPYMIALAALYLACIMKekq-----lspKMVEWFAELN 194 Capsaspora owcz...
PRW60744     108 SPYPSLSKFLRDSGlv-ahTKACEAAWSVLSDSYRTPLHVmHPPHVIALGALCLAATITq---------lDLRSWLNGLD 177 Chlorella sorok...
XP_005709979 151 HPYRPLVQYCADANm----TDLLTSAWPILNDSYRTDACLrYPPYLIAVACIFIAGTLQd---------rDMKEWLQKLG 217 carragheen
PRP80693     148 HPYRSLIDYLSDCKl---sKGPMDMAWNLLNDSYCTELSLtCSPYIIALAAIYIASTVCe---------vDLRGWFSELN 215 Planoprotosteli...
XP_004367458 105 HPYRALTQFTSDAVm---sLNFLENAWYLVNDSYRTDVMLmYPPHIVALAAMMMIAHKDg---------vNLRPWLATLN 172 Acanthamoeba ca...
CEP00638     136 HPYRPITLYLSHIGl----NECLQTAWAIANDSYCTDVCLlYPPHVIAVACIQMAANFHe---------kDIREWSQKLR 202 Plasmodiophora ...
Q9FJK6       146 HPYRSLSEFLQDAAln--dVNMNQITWGIVNDTYKMDLILvHPPYRIALACIYIASVHRe---------kDITAWFEDLH 214 thale cress

5FGK_B       224 VDMeKILEIIRVILKLYEQWKNFD 247 human
CBY23085     254 LDLkQLAKITKDILNMYGVWAKFP 277 Oikopleura dioica
XP_002682418 247 VDMkVIGDITEEILNMYSILRRIN 270 Naegleria gruberi strain NEG-M
KJE91914     195 VNPeELIEIATPILALYETWETFS 218 Capsaspora owczarzaki ATCC 30864
PRW60744     178 ADFaAAHEVAAEMLSFYERHATPI 201 Chlorella sorokiniana
XP_005709979 218 IDLqELGDVTQYLSTLYVNPNPVR 241 carragheen
PRP80693     216 VEMrEVMAASSELLEYYESIKRME 239 Planoprotostelium fungivorum
XP_004367458 173 VDMkEVWVVLETLLDLYIVWNKMS 196 Acanthamoeba castellanii str. Neff
CEP00638     203 IKMdQVFEVIAEILSYYDYRSKHT 226 Plasmodiophora brassicae
Q9FJK6       215 EDMnLVKNIAMEILDFYENYRTIT 238 thale cress
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