Conserved Protein Domain Family
GTPase_binding
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pfam09027: GTPase_binding (this model, PSSM-Id:401099 is obsolete and has been replaced by 430374)
GTPase binding
The GTPase binding domain binds to the G protein Cdc42, inhibiting both its intrinsic and stimulated GTPase activity. The domain is largely unstructured in the absence of Cdc42.
Links
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Statistics
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PSSM-Id: 401099
Aligned: 30 rows
Threshold Bit Score: 76.2483
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_017719459  481 LSAQDISQPLQNSFIHTGHGDSDPRHCWGFPDRID-ELYLGnpM--DPPDl---LSVELSTSRPPQHLGGVK 546  black snub-nosed monkey
4_pfamImport    1 PNASFISTPLKGSLQHTGHGDVHPQRSWGTPDSLDdEASIGppPrpPPPNf----------KRPNMKSQRRP 62  
XP_014432547  440 MP--RISLPVRSSFQHMGHGDLDPGRSWGAPDSMD-D-RKGkpR--DSKEs---AGLKLGG---QQLLRLTR 499  Chinese soft-shelled ...
RWS11635      473 IHPEVISLPLKNSFIHTGHGGIDGR-IWGSPRSID-EMYIKnpM--KPPDvtnnFHRDLPS--PPKLLNRNK 538  Dinothrombium tinctorium
ETN77200      208 IGNTMISLPIRGSFIHAAHGDVLGKESWGSPKKID-DIYLNhpVvgDPIDt---IV---------DIPDRVS 266  Necator americanus
EYC38147      140 ATKEKLSVEILGSFIHAGHGDVLGKESWGTPERID-DLYLRnpVlgDPLNv-----TMMGV------PAMVS 199  Ancylostoma ceylanicum
PAV68664      468 QNNSRISLPVKGSFIHAGHGDARTGQTWGDPGKIN-DVYLKnpV----------LGQPLTLSNGAMLVPTVH 528  Diploscapter pachys
OZF99701      476 DRTSRISMPVAGSFIHTGHGDPLGGQSWGNPSTID-DTYLKnpV----------KGVPLSS-----MSNGAQ 531  Caenorhabditis latens
Q10925        471 DRTSKISMPVAGSFIHTGHGDPLGGQSWGNPATIA-DMYLKnpV--NGAPl-----SSMSS-------GAEI 527  Caenorhabditis elegans
XP_020305596  271 IDNY-ISKPVRGSFIHAGHGDINVEQSWGQPDYID-DIYLKnpI----------LRKEEST---------YD 321  eye worm
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