?cl00061: FH Superfamily (this model, PSSM-Id:381782 is obsolete and has been replaced by 469596)
Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as monomers, are also found in the Hepatocyte nuclear factor (HNF) proteins, which provide tissue-specific gene regulation. The structure contains 2 flexible loops or "wings" in the C-terminal region, hence the term winged helix.
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Jiyao W et al.(2023). "The conserved domain database in 2023.",