Conserved Protein Domain Family
zf-C4pol
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pfam14260: zf-C4pol (this model, PSSM-Id:372984 is obsolete and has been replaced by 464119)
C4-type zinc-finger of DNA polymerase delta
In fission yeast this zinc-finger domain appears is the region of Pol3 that binds directly to the B-subunit, Cdc1. Pol delta is a hetero-tetrameric enzyme comprising four evolutionarily well-conserved proteins: the catalytic subunit Pol3 and three smaller subunits Cdc1, Cdc27 and Cdm1.
Links
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Statistics
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PSSM-Id: 372984
Aligned: 255 rows
Threshold Bit Score: 36.5791
Created: 29-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
LoveMIT:GQ68_00626T0          1385 CLVCG-------------TnlprgnksKICRQCQnSPLEV--VTSLGAKIHNAEKKVQNIFNLCEFCssghalflpnfqn 1449 Komagataella phaffii GS115...
CCH60643                      1249 CVHCRvrsrkkdvdgvgwS--------QFCDEC--SQDRQklCVDLLTQKRNLETKHACVNWKCRGCnfaytgdi----- 1313 Tetrapisispora blattae CBS 6284...
CCE62779                      1398 CINCH-------------Qsftt-gistLCSDCSnQKSAT--AVNLIESIRKSETAYENIQTVCRVCsfky--------- 1452 Tetrapisispora phaffii CBS 4417...
WGS:AATM:SJAG_00153           1364 CCLCLknpvta-vpnaptS--------LLCEDC--RQHSDkaLMNTLYNLNSSSLLFNRLSHICEGC------------- 1419 Schizosaccharomyces japonicus yFS275...
EPY53375                      1390 CSSCLrnmvsn-qnssenK--------YLCDDC--LRNIPaaTTRVIQQSKDVAVRLARLEDICRGC------------- 1445 Schizosaccharomyces cryophilus OY26...
CCE89971                      1381 CIKCR-------------Geigk-sdsLLCENCLsDRPLT--ASQLILRTTSNESRLRSISTVCRTCcyry--------- 1435 Torulaspora delbrueckii...
XP_001949189                  1396 CILCSkl---------sqH--------GFCEQC--QQNPQylIVQLNHLLSKWTKKQDDLETICRSCcgr---------- 1446 pea aphid...
Q6CB61                        1246 CIVCKtaqt--------------sglsKLCATC--ESDPGhaTFVLNSDLRYREKRLDELNTICAQCsg----------- 1298 Yarrowia lipolytica...
Q233J3                        1670 CIACSnk---------tkN--------QICENC--LQDPSalIFILTQKKKINEMKLQKLIDKCTNCcnlsq-------- 1722 Tetrahymena thermophila SB210...
WGS:AAGF:cds.TTHERM_00437650A 1643 CIICYer---------csE--------DICNSC--LSDIPtlSYLLSHKQQIIHSQYQEIERKCKNC------------- 1690 Tetrahymena thermophila SB210...

LoveMIT:GQ68_00626T0          1450 fnsvKFLT------ASSCENQNCILYYKR 1472 Komagataella phaffii GS115
CCH60643                      1314 ---------ldagaaeRCISAECPIFFER 1333 Tetrapisispora blattae CBS 6284
CCE62779                      1453 shdaGPINsd---iSSNCISLDCPVYFSK 1478 Tetrapisispora phaffii CBS 4417
WGS:AATM:SJAG_00153           1420 ----SRISsv---dPIYCNSQNCCIYYER 1441 Schizosaccharomyces japonicus yFS275
EPY53375                      1446 -------ScisssdPVLCRSKSCKIYYDR 1467 Schizosaccharomyces cryophilus OY26
CCE89971                      1436 sndaSEVSdh---iGDCCNSYDCPVYFGR 1461 Torulaspora delbrueckii
XP_001949189                  1447 ------------nfELKCNSLNCQIYYga 1463 pea aphid
Q6CB61                        1299 ------------dfETRCESQDCPIYYSR 1315 Yarrowia lipolytica
Q233J3                        1723 -----------ieempQCIQYECYTYFEK 1740 Tetrahymena thermophila SB210
WGS:AAGF:cds.TTHERM_00437650A 1691 -----SSLenkeieEVPCVEYNCPYLYAK 1714 Tetrahymena thermophila SB210
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