Conserved Protein Domain Family
MAD
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pfam05557: MAD (this model, PSSM-Id:368498 is obsolete and has been replaced by 461677)
Mitotic checkpoint protein
This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Links
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Statistics
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PSSM-Id: 368498
Aligned: 13 rows
Threshold Bit Score: 525.846
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ADK12653             53 AAERVRSHTSLIQLTQEKQQMELSHKRARIELEKEahsssrdLQREIDRNRDLQMKIRRLEERE-EKANQALNEQMENNK 131 zebrafish
P87169               54 NPKLASLEFQLENLKNDLKRKELEFEREQIELQRK-------LAEEHEQKNSLQLRLTLVEKQL-EEQSTSYQKEIEEVR 125 Schizosa...
XP_013025869         41 SSRVQSLEFALENAKNDLKQKEIESDRERNDLLAK-------LTEEREQSKAFQIRVSLLEKQE-HEREATNHETIERLR 112 Schizosa...
WGS:AAQB:GK15834-PA  83 RAELIESKAIVSQLQRDMEREAKEYRSELAISESKaaalkeqCDYTSAKMQELEKHLQVVRKREqVASESASRANVELAQ 162 Drosophi...
XP_002050330         85 RAELIESKAIVSQLQDQLAQQAKEQRSALALAESKatalkqqCDYTSAKLLEQDKQLQVVRKREhNARQEANRAMAEMAQ 164 Drosophi...
Q7KND8               80 RTELIETKAIVIQLRNEIEKKSREHKEAILLAENKstalkdqCDITSKKNLELQDDLKALRKRElVLKNEASRATAELNQ 159 fruit fly
XP_001959874         79 RADIIELKARNSQLQHEVERQIKEHRRAMAVAESKstalkqqCDITSKKMIEMERNVQIMRKREvALKEEACSARAELAQ 158 Drosophi...
EDW36037             82 RAELIETKARLSQVQDQLKQNETKRRMELSLAESKvsalktqCDFTSQKLLDLTKDMENRRGLEnSYKEEARRAKAELAG 161 Drosophi...
XP_005054501         54 QAGQIHSKSQLLQVEREKMQMELSHKRARIELEKAantnarnYEREADRNQELLTRIKQYQERE-AEAENKLKEQMEMNK 132 Collared...
Q9WTX8               54 RAEQIRSKSYLIQVEREKMQMELSHKRARVELERAastnarnYEREVDRNQELLARIRQLQECE-ATAEEKMREQLERHR 132 house mouse
NP_001095514         54 RAEQIRSKSHLIQVEREKMQMELSHKRARVELERAastsarnYEREVDRNQELLTRIRQLQERE-AEAQEKMKEQLERHR 132 cattle
XP_006637049         53 EAQKIFSKTHLLQMAQEKSQMEFSHKRARIELEKAahtsardLEREVDRNQDLLARIRKLEEKE-SEAGKALKEQTEISR 131 spotted gar
XP_018558114         52 AAEQVYSKNRYLQLDQEKKQMEMSHKRARFELEKAasdsardLEHEIDRNQELLGRIKKLEERE-TEAAKNLSEQVEANR 130 barramun...

ADK12653            132 alkrnleelhkkaNEKDSKLTEAEQIISELKDETRRLGQQIQIQESKFSTQNLEIQALQEQLDVQRKKFQDISQKY---- 207 zebrafish
P87169              126 -------------NEKEATQVKIHELLDAKWKEIAELKTQIEKNDQALSEKNHEVMVSNQALQMKDTNLTNLEKLFadsr 192 Schizosa...
XP_013025869        113 -------------SDNESLVLQLSELKSNLTQETAARATELEKTQQELREKIYKVEDFQQRNKLLEENASQMEIRNsslq 179 Schizosa...
WGS:AAQB:GK15834-PA 163 qktkyeaiinqleKTKMQQEGDARDVHLCIGNELNEYRRLAQRANLELQSTRNELERIQRRHDEYKARISNYEELK---- 238 Drosophi...
XP_002050330        165 qklkyetalsraeQEKTQLEEDAREVQHCINNELSEYKRISERAELELEATQSELERIRERHDEYKATAANYEQLQ---- 240 Drosophi...
Q7KND8              160 lrlkfdestlklqKEKYLQKEDARDVHLCINNELSEYRRIAQRADLELQSTRNELERLRQLNEELQARASGFEQLR---- 235 fruit fly
XP_001959874        159 lkmkfddsidslqKEKSQQEEDARDVQLCINNDLAEYRRMAHRADLELQATRTELERFRRRHDEFKARVSGHEDLR---- 234 Drosophi...
EDW36037            162 lklkydetvnklkNEKSQQEQDARDVQLCINNELGDYRRQAQRAELELQSTLKELECIRQRHDEYKARMSGYEELR---- 237 Drosophi...
XP_005054501        133 sykksmetmskkiQEKESKLAEANETITVLKGKISELQWNIMNQEMQMTSQDSEKQELMEQLDIEKKKWQEASQQI---- 208 Collared...
Q9WTX8              133 lckqnldavsqqlREQEDSLASAREMISSLKGRVSELQLSAMDQKVQVKRLESEKQELKEQLELQQRKWQEANQKI---- 208 house mouse
NP_001095514        133 lcqqsldaagrklREKEDGLAEAGETITTLKGRLSDLQWSMMNQEMQVKRLESEKQELKEQLDLQHQKWQEANQKV---- 208 cattle
XP_006637049        132 slkktiegqnkklEEKDSKLAEANETSRALRDEIRELHHKIKNQEIQLTTQTTENQGLQEQLELLHKKCQEATQKI---- 207 spotted gar
XP_018558114        131 alrknleglnkklEERDSRLNTANQTVSSLKDEIRELKQKIQNKDSTISTQTLENQELQEQLDLQRRKYQEVSQVC---- 206 barramun...

ADK12653            208 QNLQSSHSTSTESELKMKELERRLAL------QEQDSVIVKNMKSEV-ARLPEMEREIKRLREENSFLRETKENNSLLKE 280 zebrafish
P87169              193 EQLETKCKELAAAEQQLQELSVHNQQleesikQVSSSIELEKINAEQrLQISELEKLKAAQEERIEKLSSNNRNVEILKE 272 Schizosa...
XP_013025869        180 EQLNSKLKESLDKEQQVQTLIFEIEKlkesvnQASDSLELKDANQKLlERIAELEKLQEKHLYMIERYNTNSRNIEIVNE 259 Schizosa...
WGS:AAQB:GK15834-PA 239 SNYEKQQHSLKTANERIKELEYEIQS------YNDWKEVTKASQDRL-ASIPDMQAELDRLRGHNKHLNSLIGDKLLLEE 311 Drosophi...
XP_002050330        241 MSYEMQQQTLATANARIKELEYEIQS------YADWKEITKTSQARL-LSVPELQSELERLRAHNKQLNSLIGDKLLLEE 313 Drosophi...
Q7KND8              236 ANHEKQTQSLKVANDRIQELEFEIQS------YSDWKEVVKTSRERL-ASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEE 308 fruit fly
XP_001959874        235 SDFEKQSQSLKAANERIKELEYEIQS------YNDWKEVTKASQERL-ASVPDLQSEIERLRHHNKHLNTLIGDKLLLEE 307 Drosophi...
EDW36037            238 ANFEKQQQSLKVADERIKELEFEIQS------YTDWKQVTKVSQERL-ASIPEMDSELQRLRVHNKQLNKIIGDKLLLEE 310 Drosophi...
XP_005054501        209 QTLQASQSLLAEYEQKIKDLEQKLSQ------QEHDALIVKNMKAEL-ARFPKMERELRQLKEENAYFREMKENNGLLKE 281 Collared...
Q9WTX8              209 QELQASQDERAEHEQKIKDLEQKLCL------QEQDAAVVKSMKSEL-MRMPRMERELKRLHEENTHLREMKETNGLLTE 281 house mouse
NP_001095514        209 QELQASQEVRADQEQRIKDLEQKLSL------QEQDAAIVKNMRSEL-VRLPTMERELRQLREENACLRETQDTNGLLRE 281 cattle
XP_006637049        208 QALQMYPSLNSENELKIKELERRLAM------QEQDSVIVRNMKSEL-GRIPDMEKELQQLREENAYLRETKENNNLLKE 280 spotted gar
XP_018558114        207 QNLQAAQSSCSEHIIKIKELERRLAL------QEQDIAIVKTVKSEV-ARVPDLEKELKRLRDDNAFLRESRENCSLLKE 279 barramun...

ADK12653            281 ETEGLRRKLERLEKVMEEKIKVELEKEKMERELQAWENIGQAtg--lNIRKPEDLSREVIQIQQRELNFKQQNYSLNSSV 358 zebrafish
P87169              273 EKNDLESKLYRFEEYRDKVATLELENEKIQTELNSWKSLITN-----ELPTPEAVSNKLVFLQNTNANLGERVSSLESQL 347 Schizosa...
XP_013025869        260 EKADLEAKLYQYEDYKEKVAVLGVDNEKLQAELNSWKKTFM------DMNVPELAAEKFKTLQSENKTLSERVSDLTQQL 333 Schizosa...
WGS:AAQB:GK15834-PA 312 QVHHYKTRLEKEEGARAEAASLQVKLSHVEQELKEWVKIAQDhclanTLVSPIALRARIEQLLQEDIVHVAEKTSSESDS 391 Drosophi...
XP_002050330        314 QVHDYKTRLDREEGARAEAATLQVKLTHVEQELKEWVKVAQDhclpnTLVSPMALRTRIEQLLQDDIVRMAEKGSADSDS 393 Drosophi...
Q7KND8              309 QVYDYKTRLEREEGARAEAASLQVKLLHMEQELKEWVKVAQDhclanTLVSPMALRSRIEQLLKEDIIHVAEKTSSASDT 388 fruit fly
XP_001959874        308 KVHDYKTRLDREEGARAEAVSLQVKLSHVEQELKEWVKVAQDhclpnTLVSPMALRSRIEQLLQEDIVHVAEKTTSESDT 387 Drosophi...
EDW36037            311 QVHEYKARLDKEEGSRAEAAALQVKLSHTERELKEWVKVAQDhclanTLVSPVTLRSRIEQLLQGDIVHVSEKYASESES 390 Drosophi...
XP_005054501        282 EVEGLQRKLERYEKVQAQLVTVELENEKLLGKLQSWEKLDQStg--lNIRTPDDLSRQIVALQQRELALKEQNSTFMNSA 359 Collared...
Q9WTX8              282 ELEGLQRKLSRQEKMQEALVDLELEKEKLLAKLQSWENLDQTmg--lNLRTPEDLSRFVVELQQRELTLKEKNNSITSSA 359 house mouse
NP_001095514        282 ELEGLQRRLGRQEKMQETLVDLELEKERLLTKLQSWERLDQTtg--lSIRTPEDLSRFIVELQQRELALKDKNSAITSSA 359 cattle
XP_006637049        281 EAEGMRKKLERVEKMKEDLVKLELEKEKLSLKLQAWQNLEQMtg--lNIRRPEDLSGEIIQFQQREITLKQQNYSVTSSA 358 spotted gar
XP_018558114        280 EVEGLRRKLERMEKTKEELVNMELDKERLAEKLQAWENLGQStg--lNIRKPEDLSREVIQIQQREIALKEQNYTLNSRV 357 barramun...

ADK12653            359 RSVEKARSELLTEIAQLraKAQEEQKKRENQDSLVRRLQKRVLLLTKERDGMRAILESYDSE---LATSEYSPQLTLRVK 435 zebrafish
P87169              348 SNKPANQPLGANEKDAA--HITELETKLKELHEQNRRLQRQKSLATQEIDLLRENLKSYDDEeaiLSEKNTDMKKLERIE 425 Schizosa...
XP_013025869        334 LQERIQGPPMVIELKN---KVTDLKNENKETSEQIRRLQRQVFLANQEINLLRANLKSYDDEeaiMNNEKSGQKKLERIE 410 Schizosa...
WGS:AAQB:GK15834-PA 392 KHLHSTIKDLEQKCAAYlkNIEDLNIGLKRHKNFKERLQRKLIIVSKERDFYKQLLENFDKD---QTLNNTS-------- 460 Drosophi...
XP_002050330        394 KQLQSSLRELEQKCAVYlkNIEDMNVVLKRHKSFRERLQRKLLIVCKERDFYKQLLENFDKD---LNMTNAS-------- 462 Drosophi...
Q7KND8              389 KHLNTTIRDLEHKCAIYlkNIEDLNIGLKRHKNFKERLQRKLITVSKERDFYKQLVENFDKD---TTLSNAS-------- 457 fruit fly
XP_001959874        388 KHLQATVRELEQKCSVYlkNIEDLNIGLKRHKNFKERLQRKLITVSKERDFYKQMVENFDKD---LTMSNTS-------- 456 Drosophi...
EDW36037            391 KQMRNLVRDLEQKIRVYlkNIEDLNMSLKRHKNFKDRLQRKLRTVSRERDFYKQMVDNFDKD---LTMSNAS-------- 459 Drosophi...
XP_005054501        360 RMLEKARQQLQEEILSVqsQLLDEKKKREHQEALVRRLQKRVVLLTKERDGMRAILESYDSE---LSPAEHSPQLSRRMR 436 Collared...
Q9WTX8              360 RGLEKVQQQLQDEVRQAnaQLLEERKKRETHEALARRLQKRNALLTKERDGMRAILGSYDSE---LTQTEYSTQLTQRLW 436 house mouse
NP_001095514        360 RELEKARLQLQDEVRQLggQLLEERKRRETHEALARRLQKRVLLLTKERDGMRAILGSYDSE---LTPAEHSPQLTRRMR 436 cattle
XP_006637049        359 RALEKVRLELQNELLQLraKLLEEQKRREQQDALVRRLQKRVLLLTKERDGVRAILESYDNE---LTASEYSPQLSQRVK 435 spotted gar
XP_018558114        358 RSVERSQTELRAELSQQrsKTLEEQKKRESQDALVRRLQKRVLLLTKERDGMRAILESYDSE---LAPTEYSPQLSKRLR 434 barramun...

ADK12653            436 EAEDMLQKVQAHNAEMETQLSKAQeeagsfklqaQMVAAELEALKeQQVSNAERSSsvtaeeISSLRQKIEELEAERQR- 514 zebrafish
P87169              426 GLVKLVDEYKLKLESMPVSLDVDE----------TSDEVSLQKRR-RKNEHKDAGY------VTELYRKNQHLLFQVKEk 488 Schizosa...
XP_013025869        411 SLTQLIDEYKVLFENSKIynq-----------gaSADEQSLTLKRpRNEDQEDVGY------VTELYRENQHIQLQLQEk 473 Schizosa...
WGS:AAQB:GK15834-PA 461 -AADMTQDMH-----VRHRIEVLErtvtgykdicATLEREIQAMR-QQEQLHEPtn----egYDSVKKELDTLRLENER- 528 Drosophi...
XP_002050330        463 -TAEMTNDMQ-----VRYRVEVLErtltgykemcSTLEREMQSMR-QQESLNDPPise--ngYDSVKRELDTLRMENER- 532 Drosophi...
Q7KND8              458 -VADMTQDMQ-----VRVRMEVLErtvtgykdmcATLEREIQSLR-QQELVNEPag----egYDSVKKELDTLRMENDR- 525 fruit fly
XP_001959874        457 -MADMTLDMQ-----VRYRMEVLErtvtgykdmcATLEREIQAMR-QQEQLAEPsg----egYDSVKKELDTLRLENDR- 524 Drosophi...
EDW36037            460 -VAEMTQDMQ-----VRYRVDVLErtltgykdlcTTLDREIQAMR-EQEQLSDPss----edYENVKKELDTLRLENDR- 527 Drosophi...
XP_005054501        437 EAEDMVQKLHAHNAELEAQLSQVLeevgshkqraEMLEVEMKVLK-SQQCTAEQSTvvtkeeVDTLRLKIEELEAERSK- 514 Collared...
Q9WTX8              437 EAEDMVQKVHAHSSEMEAQLSQALeelgvqkqraDTLEMELKMLK-AQTSSAESSFsfckeeVDALRLKVEELEGERSR- 514 house mouse
NP_001095514        437 EAEDMMQKVQAHSSEVEAQLSQALeelggqkqraDMLEMELKILK-SQAAPAEQSFlfsreeVSSLRLKVEELEAERSR- 514 cattle
XP_006637049        436 EAEEMLQKVQTHNSEMEAQLSKAQeeagayklqaQVAEAEIDILK-KQAATADNSSfvsteeVNSLRQKIEELEAERRR- 513 spotted gar
XP_018558114        435 EAEDVLQKTQNHNAEMEAQLTKAQeetgtlrlqlQTVELELDSLKkQQASAADSSSlatkeeVSILRQKIEDLEAERQR- 513 barramun...

ADK12653            515 ------LEEQNNILEMRLE--RHNLQGDYDPVKTKVVHLQMNPTSMAKQQRADEVEQLRVECQRLRDRLRkievag---- 582 zebrafish
P87169              489 tnieafLREQIITLESSIAtlRQELAQVTEINSCRVLQHRSNPTLKYERIKAAQLEMLNAENSALKALLE---------- 558 Schizosa...
XP_013025869        474 lntegfLRDQINGLEVIIAelRQEIIQMSELKSSKVLQHRSNPTLKHERVKAEQLHLLEKENGGYKAILE---------- 543 Schizosa...
WGS:AAQB:GK15834-PA 529 ------LRRRKDELELEMV--NRSLRGT-DTANHKVVHLSQNPAAEAYECSKNMMEKLQAEIERLKRRIKkme------- 592 Drosophi...
XP_002050330        533 ------LRRRKDELELELE--HRCLRGDFNMGNYKVLHLSENPAADAYEATKNVVEKLQAEIERLKRRNKkle------- 597 Drosophi...
Q7KND8              526 ------LRRRKEELEMEMM--HRCLRGDFNMKDFKVVHFSENPAAEAYESTKNMMEKLQAEIERLKRRNKkle------- 590 fruit fly
XP_001959874        525 ------LRRRKEEMELELM--HRCLRGDFNMKEFKVVHLSENPAAEAYESSKNVMEKLQAEIERLKRRNKkle------- 589 Drosophi...
EDW36037            528 ------LRRRKEEQELEIM--QRCLRQDISPPISKVVHLVDNPAAEAYESSKNMLEKLQAEIERLKRHNKkle------- 592 Drosophi...
XP_005054501        515 ------LAEENRSLEMKLE--KLTLQGDYDPSRTKVLHLSMNPMSLAKQQRKEEQQQLQEECERLRELVRvlkggg---- 582 Collared...
Q9WTX8              515 ------LEQEKQVLEMQME--KLTLQGDYNQSRTKVLHMSLNPISMARQRQHEDHDRLQEECERLRGLVHalergg---- 582 house mouse
NP_001095514        515 ------LEEEKKTLEAQLE--RLTLQGDYDQSKTKVLHLSQNPAGAARQRLREDQQQLQEECARLRELVRaleagg---- 582 cattle
XP_006637049        514 ------LEEQNNMLEMRLE--RHNLQGDYDPTKVKVLHFRMNPASQARQQRAQDAEQLRQELQRLKEHIQllqagg---- 581 spotted gar
XP_018558114        514 ------LEEQNNVLEMRLE--RHNLQGDYDPVKTRVLHLKMNPTAVAKQQRQQEVEALREEVTHLRELVRslqdggslvh 585 barramun...

ADK12653            583 ---------------gmttdD-TTLIIPPS--------------QEILDLRKQMESAELKNQRLKEVFQKKIQEFRTACY 632 zebrafish
P87169              559 --------------------DkKVDCLPIQsfk--------iaeRKALDLKKEVAEREKRIQRLKEIFSVKSLEFREAVF 610 Schizosa...
XP_013025869        544 --------------------EkDIQTVPMEsle--------lanRRTLELKKELLDRDKRIQRLKEIFSVKSLEFREAIY 595 Schizosa...
WGS:AAQB:GK15834-PA 593 -----------------edsEq-----ATTtditsasagmtmnfKELNQMRADLESANAKMRKMKDCFKAAGKEFRDVVY 650 Drosophi...
XP_002050330        598 -----------------edqEqTQARFNETvgsssagggmtmnfKEFNQLRAELESANGKMKKMKDCFKAASKEFRDVCY 660 Drosophi...
Q7KND8              591 -----------------ddnEq---RLNETtstgg----mtlnfKEFNQLQAELESANGKMRKMRDCFKAAREEFRDVCY 646 fruit fly
XP_001959874        590 -----------------ddqEq---RLNETtstgg----mtmnfKEFNQLRAELESANGKMRKMKECFKAATTEFRDVCY 645 Drosophi...
EDW36037            593 -----------------danEq---HLNETtststg--gmtmnfKELNKLRAELESANAKLGKTKEYFMAARKEFRDVVY 650 Drosophi...
XP_005054501        583 --------------slsgelE-GVGAFQSP--------------QEVAELKKQVESAELKNQRLKEVFQTKIQEFRKVCY 633 Collared...
Q9WTX8              583 --------------pipadlE-AASSLPSS--------------KEVAELRKQVESAELKNQRLKEVFQTKIQEFRKVCY 633 house mouse
NP_001095514        583 --------------pvpahlE-AGAGLPSS--------------REVAELKKQVESAELKNQRLKEVFQTKIQEFRKVCY 633 cattle
XP_006637049        582 ---------------avaaeE-GPLSLPPS--------------QEVLDLRKQVESAELKNQRLKEIFQKKIQEFRKVCY 631 spotted gar
XP_018558114        586 sqddssmhssslglslppskE-IL------------------------DLRKQMESSELRNQRLKEVFQRKIQEFRTVCY 640 barramun...

ADK12653            633 VLTGYQID-ITVENQYRLTSVYAEHMEDSLLFkstgPVGsGSMQLLETDFSRTLTGLVDLHLFHQKSIPVFLSAVTIELF 711 zebrafish
P87169              611 SLFGYKLD-FMPNGSVRVTSTYSREDNTAFIF----DGEsSTMKLVGNPSGPEFERLIRFWCDERKTIPGMLAALTLELL 685 Schizosa...
XP_013025869        596 SLFGYKIE-FLPNGSVRVTSMYSHENNTAFVF----DGEtSTMKLVGKPSSPDFERLVRFWCDERKTIPGMLAALTLELI 670 Schizosa...
WGS:AAQB:GK15834-PA 651 MLLGYRVDrMGANSNYRISSMYAENPTDYFDItlseSNC---LALLESPYSQTLKPAIDQQLAANNSFPAFFSSLTLELF 727 Drosophi...
XP_002050330        661 MLLGYRIDrVGANSHYRISSMYAESPDDYLSIslneSNC---LALLESPYSQTLKPAIDQQLAANNSFPAFFAGLTLELF 737 Drosophi...
Q7KND8              647 MLLGYRIDrIGANSNYRISSMFAEGPDDYLDIslneSNC---LALLESPYSHTFNPPIDQQLAASN-FPAFFSALTLELF 722 fruit fly
XP_001959874        646 MLLGYRIDrIGANSNYRISSMYAESPEDYLDItlneSNC---LALLESPYSRTLKPAIDQQLAASNSFPAFFSALTLELF 722 Drosophi...
EDW36037            651 MLLGYRIDrVGYKSNYRVTSMYAESPDDYFSIalseSND---LALLETPYSETLQPALDQQLAANNSFPPFFSSLTLDLF 727 Drosophi...
XP_005054501        634 TLTGYQID-ITTENQYRLSSIYAEHQGDCLLFkassSSG-GKMQLLETEFSRTVRELIELHLLRQDSIPAFLSALTLDLF 711 Collared...
Q9WTX8              634 TLTGYQID-VTTESQYRLTSRYAEHQTDCLIFkatgPSG-SKMQLLETEFSRSVPELIELHLLQQDSIPAFLSALTIELF 711 house mouse
NP_001095514        634 TLTGYQVD-ITTESQYRLTSMYAEQKADCLIFkaagPSG-TKMQLLETAFSRTVPGLIELHLLQQDSIPAFLSALTLDLF 711 cattle
XP_006637049        632 MLTGYQID-ITTENQYRLTSVYTERVEDSLLFkasgPTG-GNMQLLETDFSRTLHDLVELHLFHQKSIPAFLSAVTLELF 709 spotted gar
XP_018558114        641 VLTGYQID-ITTENQYRLTSVYAEHMDDSLLFkk-gSNG-S-MQLMETEFSKTLGEMVALHLHHQKSIPAFLSAVTLDLF 716 barramun...

ADK12653            712 SRQT 715 zebrafish
P87169              686 DKND 689 Schizosaccharomyces pombe 972h-
XP_013025869        671 DKND 674 Schizosaccharomyces cryophilus OY26
WGS:AAQB:GK15834-PA 728 QRST 731 Drosophila willistoni
XP_002050330        738 QRAT 741 Drosophila virilis
Q7KND8              723 QKAT 726 fruit fly
XP_001959874        723 QRAT 726 Drosophila ananassae
EDW36037            728 QRAT 731 Drosophila persimilis
XP_005054501        712 SRQT 715 Collared flycatcher
Q9WTX8              712 SRQT 715 house mouse
NP_001095514        712 SRQT 715 cattle
XP_006637049        710 SRQT 713 spotted gar
XP_018558114        717 SRQT 720 barramundi perch
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