Conserved Protein Domain Family
DUF4939
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pfam16297: DUF4939 (this model, PSSM-Id:318516 is obsolete and has been replaced by 465086)
Domain of unknown function (DUF4939)
This family consists of uncharacterized proteins around 110 residues in length and is mainly found in various mammalia species. LDOC1, a member of this family and a novel MZF-1-interacting protein, inhibits NF-kappaB activation and relates with cancer and some other diseases. But the specific function of this family is still unknown.
Links
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Statistics
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PSSM-Id: 318516
Aligned: 5 rows
Threshold Bit Score: 192.377
Created: 24-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9D6I0         2 DRR-IKLIMALMAWPELrk--gRWQNPIPFPELFDGEMEKLPEFIVQTLSYMLVDEKTFDTDKRKVMFLITRLKGRALQW 78  house mouse
XP_005001429   2 DGR-EQLTKVFMGWPRP-----RWRNPIPFPETFNGDTDRLPEFIVQTGSYMFVDDKTFSSDALKVTFLITRLTGRALEW 75  domestic guinea...
XP_002763340   2 DGR-VQLMKALLAWPLLpa-rrRWRNPIPFPETFDGDTDRLPEFIVQMGSYMFMDENTFSNDALKVTFLITRLTGPTLQW 79  white-tufted-ea...
XP_011222670  61 DGRpSALIKALLALPLRpq-tqRWRNPIPFPETFDGDTDRLPEFIVQTGAYMLVDETLFSSDALKVTFLITRLTGPALQW 139 giant panda
XP_017443841  24 NQLlKQLRILVCERARLlrqvrLPSCPVPYPSRFSGESGRLPEFVVQTMSYMLVNEEHFCNDAMKVAFLISLLSGEAEEW 103 Norway rat

Q9D6I0        79 AMRYLQTDSPMLNNYSGFLNEMKEEFGWE-EDEDF 112 house mouse
XP_005001429  76 VMPYIQKDSPLLNNYRAFLAEMKLVFGWEdDEEDF 110 domestic guinea pig
XP_002763340  80 MIPYIKKQSPLLNDYWGFLAEMKRVFGCQ-EDKDF 113 white-tufted-ear marmoset
XP_011222670 140 VIPYIRKESPLLNDYRGFLAEMKRVFGWV-EDEDF 173 giant panda
XP_017443841 104 VMPYIESNSYILGDYRAFVNEMKQYFGWDtDDEDD 138 Norway rat
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