2XPI


Conserved Protein Domain Family
ANAPC3
?
pfam12895: ANAPC3 (this model, PSSM-Id:315555 is obsolete and has been replaced by 463743)
Click on image for an interactive view with Cn3D
Anaphase-promoting complex, cyclosome, subunit 3
Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.
Links
?
Statistics
?
PSSM-Id: 315555
Aligned: 83 rows
Threshold Bit Score: 39.1738
Created: 28-Jul-2016
Updated: 4-Aug-2016
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
2XPI_A         96 MQQQYKCAAFVGEKVL------------DITG---NPNDAFWL--AQVYCCTGDYARAKCLLTKE-D-LYNRSS---ACR 153 fission yeast
11_pfamImport   1 EKKPHKRAYLTITKISgssafkevakrfRETQ---DTDDSLFL--AKAYYNQGQYKKAEYWALQTnN-VNSGIE---ESI 71 
Q0AP33        100 ATNRADDAVIMAREAA------------TGAF---AEDAAMMHtlALALFETGRYDEAADQLAAM-Q-AAHPTLrhpEAH 162 Maricaulis mar...
Q16QW4        279 KKKKLNELEKMIAPTS------------TFPM---EYSSEMWFvmAQYLYSTAKYDKAVYFVQKAcF-LNPKNA---EAL 339 yellow fever m...
37_pfamImport   1 AAAVVTAAIFVYRNMAe-----------SKRE---KASAALYE--AQAPFAQGKFDEAQKALEKVtN-QYASTSsgqQAA 63 
A0BHU0         44 WLDNYKDAILWADKALs-----------INSK---HINSLFTK--GESLRMLGEYEDAIKILDVAlN-QNPNHD---QSL 103 Paramecium tet...
A0E2E7        127 GLGQYDEAIIWADKALq-----------VDQK---HCSSLYIK--GNSLRLLKKYKEAMKVIEQSlK-INPNHF---DSL 186 Paramecium tet...
A0DXI2         69 MLGQYNEAIIWADKALq-----------VNPQ---HCYSLFTK--GNSLRQLKKFKEAMEVIEQSlK-INPNHF---DSL 128 Paramecium tet...
Q22AJ3         11 MMMRLNTKYLLKNRFFc-----------SVQQ---DPNYIFTT--AYCHFRQENYSKTLEKLNQIqA-GNSTDL---NYL 70  Tetrahymena th...
WP_012857181  115 keieaANHLLHTERVLm-----------NHFQqmsNYENAYAL--AQFYFEQKAYYEAIAWTKKA-NkLNPNSD---VTW 177 Sulfurospirill...

2XPI_A        154 YLAAFCLVKLYDWQGALNLLGET 176 fission yeast
11_pfamImport  72 LIFAKAKVKLGRKNEAIRVLSKY 94 
Q0AP33        163 LLHARTLEALGRLDEASATYDSV 185 Maricaulis maris MCS10
Q16QW4        340 ILKAEILLQLKKYQEAIAHLRFA 362 yellow fever mosquito
37_pfamImport  64 VLLAQVLYEQKKYDEGIKALEKA 86 
A0BHU0        104 VCKGACLQSLQKYQEAINCYNQA 126 Paramecium tetraurelia
A0E2E7        187 KIKGACLHDQSQYKEALIFMKKL 209 Paramecium tetraurelia
A0DXI2        129 RIKGECLHDQKQYQQALIFYDKA 151 Paramecium tetraurelia
Q22AJ3         71 KLLAKAYIQQTEYEKGLKTLEKI 93  Tetrahymena thermophila SB210
WP_012857181  178 LIYAKSKFALGEVEVAIDALERI 200 Sulfurospirillum deleyianum
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap