2DLL,2IRF,2O6G,2O61


Conserved Protein Domain Family
IRF
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pfam00605: IRF (this model, PSSM-Id:306962 is obsolete and has been replaced by 459863)
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Interferon regulatory factor transcription factor
This family of transcription factors are important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. Three of the five conserved tryptophan residues bind to DNA.
Links
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Statistics
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PSSM-Id: 306962
Aligned: 87 rows
Threshold Bit Score: 114.551
Created: 11-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2DLL_A         8 KLRQWLIDQIDSGKY-PGLVWE-N-EEKSIFRIPWKHAGKQDYNrEEDAALFKAWALFKGKFREGIDk--pD--PPT--- 77  human
Q4H3B1        28 QFKPWLIEQISSGNY-PGLEWI-DsEQQRVFKLPWTKKNYPGW--EDHHKIFKAWAEHRSFI-RNQKpptqH--VSL--- 97  vase tunicate
BAE06511      10 PLRHWLVKKIEESAF-DGLEWV-N-REEKTFKIPWTQKKYPNW--EKHCEIFKAWAKHRGSTNLG-Dp--fD--FKK--- 76  vase tunicate
NP_001071953  26 RFTTWLVQQISSGNY-LGLEWVeG-SNKRIFKIPWTKQNFPNWA--EHHKIFEDWALLRGRWNTVTGq--pNqsFSQ--- 96  vase tunicate
XP_002107832   5 vMTDWLKEILEENAV-EGIHYV-N-GSKDTFAIKWVHASNKSYDpDCHGAIFKRWMKKSRKLDKYk----sN--YSM--- 72  Trichoplax adha...
XP_009857957  12 tLRNWLFNRLNEETYgDALKWD-G-NNKGVFHILWTKKGDPNW--ENHFQIFVGWAKHKDRFDCNSPi---N--YDK--- 79  vase tunicate
XP_009010069   2 KMRHWLLQQVESGRY-PGLRWL-D-DEMKILKIPWKHGSNSAWA-TSDGQLFYNWLAYTGKLst------cK--SKTfrr 69  Helobdella robusta
XP_002610326  14 RMRPWLEQQLDREEY-HGFCWL-D-KKERKFKVPWIHASSQHFNhMKHSAVFKAWAVHTGKYFHSFLy--qS--CRT--- 83  Florida lancelet
XP_009009851   3 LLRPWLENLIESQVV-HGLEWL-D-QKQLIFKIPWKHRSKKSWS-VEHSSVFLEWARNTGRWTPGDPe--pN--YAQ--- 71  Helobdella robusta
XP_009017166  15 LLRPWLEKNLEDGNI-EGLEWM-D-AEKTMFKVPWKHRSKKDWS-LKHSSVFLEWAKNTGRWSRGDSs--pN--FAK--- 83  Helobdella robusta

2DLL_A        78 WKTRLRCALNKSNDFEELV-ER-SQLd-ISDPYKVYRIV 113 human
Q4H3B1        98 MKSNFRTILRKCRDLEEQTnLH-QLGl-QTGNYKVYKVL 134 vase tunicate
BAE06511      77 LKGNFRCALNKSDDFEEIK-ERnVSDq-QTGNYKIYRLL 113 vase tunicate
NP_001071953  97 MKSNFRTILRKCDYIKELH-QS-HQLglQVGNYKVYKLL 133 vase tunicate
XP_002107832  73 WKTNFRCAINSLPDVMCLSaTD-SQFa-DDDKYKGYKIf 109 Trichoplax adhaerens
XP_009857957  80 LKSNFRNLIKKTTDFEEI--EN-VRNq-QTGNRKVYRFr 114 vase tunicate
XP_009010069  70 FKANFRCALKSLKDVVEVK-ER-SKKs-GKDACKVFMFL 105 Helobdella robusta
XP_002610326  84 WKANFRCALNSLPDVVELRgEN-CKAk-GEAAYKVYRIV 120 Florida lancelet
XP_009009851  72 LKTRLRCAFNKAPDILEIK-EM-HKTk-CEEAYKVYRFI 107 Helobdella robusta
XP_009017166  84 LKTRLRCAFNKAPDIEEMK-SK-HSCq-GEEPYKVYRFK 119 Helobdella robusta
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