XP_011608506 349 RLHHTRDSGCQTDDFLIActaAPSRRRIRAQRGhQGIPASLSH---STGNISSLGDQSDSTYTSVTthGGRLRSRSLPRE 425 torafugu XP_002747132 255 QRSETRDSSCQTEEVKVV---PPSMRRIRAQKG-QGIAAQMGHfsgSSGNMSVLSDSAGIVFPSRL--NSDAGFHSLPRS 328 white-tufted-... ERE84202 269 QRSETRDSSCQTEDVKVI---PPSMRRIRAHKG-LGIAAQMSHlpgSSGNMSVLSDSAGIVFPSRL--NNDADFHSLPRS 342 Chinese hamster XP_004880923 255 QRSETRDSGCQTEDVKVV---PPSMRRIRAHKG-LGIAAQMSPfsgSSGNMSVLSDPAGVTFPSRL--NSDAGFHSLPRS 328 naked mole-rat XP_006639121 368 gRSTTKDSGCQTDDILIA---APSRRRIRAQRG-QGIPTSLSH---STGNITSLPDNSDAMFAATV--GSRLRSRSLPRE 438 spotted gar XP_006005948 331 RRSGTKDSECQTEEILIA---APSRRRIRAQRG-QGTVASLSH---SAGNITVLTDESDNMFTTTV--SGRVRSHSLPRE 401 coelacanth XP_003218915 393 RRSGTRDSECQTEEILIA---APSRRRIRAQRG-QSVVASLSH---SAGNILVLTDNGDAMFTTSV--SNRVRSRSLPRE 463 green anole XP_007259457 303 RNLNTKDSGCQTDDFLIA---APSRRRIRAQRG-QGIPASLSH---STGNITSLPDRSDTMYTAAS--GTRLRSRSLPRE 373 Mexican tetra XP_005800738 267 SHLTTRDSGCQTEDFLTSg--APCRRRLRVQRG-QGVSLLLSH---SAGNISCLPDSADPMFSSSV--EARLRSRSLPRD 338 southern plat... XP_005478886 341 SHLNTRDSGCQTEDFLISg--APSRRRIRLQRG-QGVSLSLSH---SAGNISSLPETSDAMFSASV--GAHLRSRSLPRD 412 Nile tilapia
XP_011608506 426 GGRlmdsdedddddnyddddedEE----------LSPYEAEDfipSGPSPRMKMMMMKDEEESTDDQAAPEPL------- 488 torafugu XP_002747132 329 GAR-------------------AN----------IQSLEPRLg-pLGPAGDMDGTFPYQRGHPQADENSGHLG------- 371 white-tufted-... ERE84202 343 GAR-------------------AS----------TYSLESRMg-aLGSADNMDDTFRHQGGSSQGHENFAHLG------- 385 Chinese hamster XP_004880923 329 GAR-------------------AS----------AHSLg-----aLGPADDVDSSFPYQRANSHGDNNLGHFG------- 367 naked mole-rat XP_006639121 439 GGRlvded----------hdsdEE----------LSPYETEEf-lPGP-ERV----LKDEEESTDDQAMPDHQlvglkck 492 spotted gar XP_006005948 402 GARsnnlh----------hdigAE----------VSLYEPEKf-lSSP-ER----TKKEREETVNNQGPPECQpvsltcs 455 coelacanth XP_003218915 464 GAR-------------------ANevdhhntsakVSAYEAEHf-lTSQ-ER----ISAKSKDAINNPCLQEHHpiglkcs 518 green anole XP_007259457 374 GGRlrdedhdds-ddddddeddEE----------LSPYEAEDf-lPGPGQR----ILKDEEESTDDQAMPELQlgslkrm 437 Mexican tetra XP_005800738 339 SSRmmmilmdn---erndsdeeEE----------LAPFDSEGf-lPGRRER----ILKEEEESADDRAMSERQlgglkfa 400 southern plat... XP_005478886 413 TSRlldngh-------ndsddeED----------LSPFDTEGf-lTGSRK----LTLKDEEESTDDQAMSEHQlgslkyk 470 Nile tilapia
XP_011608506 489 ---QlgslKREHSWMERGRSRLPRK-AD--------------------MGSCEISSSSDTFSspIHSVSTAGG-LGSHVD 543 torafugu XP_002747132 372 ---G----ASRTGTLMRPKSQELRHfESenvtspacvvsphagystsiIPNAKLSSSSEVIA--IHTAQSAGQ-LESRSS 441 white-tufted-... ERE84202 386 ---G----ASRSGMLLRPKSQQLRFsESeniaspacvvsphaaystsvIPNATLLSSSEVIV--IHTAQSMGQ-LDSRMP 455 Chinese hamster XP_004880923 368 ---G----APRSGTFLRPKSQELRHfESetvtspacmvsphatystsiIPNATLSSSSDIII--LHTAQSVGP-LDSRMT 437 naked mole-rat XP_006639121 493 qhvG----SPDHNWNERGRSRLPRK-VD--------------------MGSCEISSSSDTFSspIHSISTTGV-LGSQID 546 spotted gar XP_006005948 456 qhiH----SPEHKLTERGRSRFPRTaAD--------------------MGSSEISSNSDTFGspIHSISTAGVlLSSQMD 511 coelacanth XP_003218915 519 qhlH----SPDHNSNERGRSRLSRM-VD--------------------SGSCDISSNSDTFGspIHSISTAGVlLSSHMD 573 green anole XP_007259457 438 qhsG----SPENSWIERGRSRLPRK-AD--------------------MGSCEISSSSDTFSspIHSVSTTGV-LGSQID 491 Mexican tetra XP_005800738 401 qlsD----SPERSWMERTGAQLPRK-AD--------------------MGSCEISSSSDTFSspVHSVSAAGV-LGSQMD 454 southern plat... XP_005478886 471 qlsQ----SPERSWMERTRAHLPRK-AD--------------------MGSCEISSSSDTFSspVHCVSAAAV-LGGQID 524 Nile tilapia
XP_011608506 544 H-------------------KEDHQSSSGNWSGSSSTCPSQTsESipPPSSPPLTG-SSHCDSELSLNTVPNAIDE--GF 601 torafugu XP_002747132 442 Sslhakiksr-dhlisrhavRDDHQSPSRHWNEGHTTMLSQA-LD--PQSSGAPTL-LSLCDSAVSLNAPANRENGsqAM 516 white-tufted-... ERE84202 456 GsstyskikprdrpmprcslKDDHQSPSHHWNERH-IIHSQA-LAssASSATT--L-LSLCDSEVPLNAPASRENGsqAI 530 Chinese hamster XP_004880923 438 Sssysri-------kprhgvQVGHQSPSHHWSDGHSSIHSQP-FDshSPSITTLL---SVCGSEVS-------PNGsqAM 499 naked mole-rat XP_006639121 547 H-------------------KEDHQSSSGNWSGSSSTCPSQT-SEtiPPAASPPLTgSSHCDSELSLNTAPHVNDDptGF 606 spotted gar XP_006005948 512 Q-------------------KDDHQSSSGNWSGSSSTCPSQT-SEtiPPAASPPLTgSSHCDSELSLNTAPHGNDDssVF 571 coelacanth XP_003218915 574 Q-------------------KDDHQSSSGNWSGSSSTCPSQT-SEtiPPAASPPLTgSSHCDSELSLNIVPSANEDsnVF 633 green anole XP_007259457 492 H-------------------KEDHQSSSGNWSGSSSTCPSQT-SEtiPPTASPPLTgSSHCDSELSLNTGSHIIDDttGF 551 Mexican tetra XP_005800738 455 H-------------------KDDHQSSSGNWSGSSSTCPSQT-SEtiPPAASPPLTgSSHCDSELSLNTATHTAEDqtSF 514 southern plat... XP_005478886 525 H-------------------KEDHQSSSGNWSGSSSTCPSQT-SEtlPPAASPPLTgSSHCDSELSLNAATHTNDDqtGF 584 Nile tilapia
XP_011608506 602 SLdpsyhsdlrpqgQGHRSSSFTSSATDQLDDAGVST------ASEGEWAYPPDQDQTDqd--tEPDQTRTLNRSQDLPQ 673 torafugu XP_002747132 517 PY------------NCRNNLAFPAHPQDVDGKSESSYsgggghSSLEPWEYKASGNGRA-----SPLKPHLATPGYSTPT 579 white-tufted-... ERE84202 531 PY------------HCRNNLNFPAHLPEVDGKSESSYsgdrghGSSEPWECRASSNGQA-----SPLKPHLATPGCSTPT 593 Chinese hamster XP_004880923 500 PC------------NCRNTLSFPAHSQDVDGKSESSSsgdrgqGSVEPWEHRASGSGRV-----SPLKPHLAAPGCSTPT 562 naked mole-rat XP_006639121 607 IIdpyq----tdkvRGHRASSFTSTVTDLLDDPGMSN------VSDGEWNYLHHQHDKScrqdfSPQRSREDESSLECPS 676 spotted gar XP_006005948 572 VTdqyly--hadksRGHRANSFTSTVADLLDDPNIg------nASDSEWGYLHHQHDASchqdfSPEHSRTD--SLGCPS 641 coelacanth XP_003218915 634 ITehytd--qidkiRGHRASSFTSTVADLLDDPNNSNt------SDSEWNYLHHHHDAScrqdfSPERPKTD--SLGCPS 703 green anole XP_007259457 552 IIdpyhm--drtqgQGHRSSSFTSSATDQMDDAGVST------ASDGEWNCNQDQQDHPcpqdfSPKHSREDESGVSCPS 623 Mexican tetra XP_005800738 515 LLdny------qglRTQRAGSFSSAAMDVLEEAGVST------PMEGEWDFPNAEPSSSqg--fSPEPGREAESSLGCPS 580 southern plat... XP_005478886 585 LLdhy------qglRTQRAGSFSSTAMDILEEVGVST------PIEGEWSYPNPEPPGSqg--fSPEPSREPGSSLGCPS 650 Nile tilapia
XP_011608506 674 EYNSKE-----G----PenqvcfsdiKTSNVDKDPSCTYSPDTEGFYsSSEHFGDCNQGYRGYMcN-YADLGPDCAQSNP 743 torafugu XP_002747132 580 SNMSSC-----S----L---------DQTSNKEDAGSLYSEDHDGYC-TSLHADSGHGSGNLCN-S-SDGFGNPRHSVVN 638 white-tufted-... ERE84202 594 SNMSSC-----S----L---------DQTSVKEDARSLYSEDHDGYS-VTTHSDSGHETGNVYNiS--DGFGNPRHSMVN 652 Chinese hamster XP_004880923 563 SNQSSC-----S----L---------DQTSTREDAGSLCSEDHAAYY-RSVHSDSGCGPGNLCN-S-SGGFENPRDNVVN 621 naked mole-rat XP_006639121 677 FTSMAT-----Y----Esf-----mdKPPSEKADSSSHFSVDTEGYY-TSMHFDCGLKASKSYIyN-YAAMGTDCGQSAN 740 spotted gar XP_006005948 642 FTSMAT-----YdsfvE---------KLPSEKAETGSHYSVDTEGYY-TSMHFDCGLKDSKSYIcS-YAATGSECRQSAE 705 coelacanth XP_003218915 704 FTSMAT-----YdsfiE---------KTPSEKADTSSHFSVDTEGYY-TSMHFDCGLKGTKSYIcN-YAAVGSESGQNAS 767 green anole XP_007259457 624 YSSGETye-sfS----G---------QPPAEKLESSSHYTVDTEGFY-TSMHFDCGLKGSRSYy-N-YAAIDPDCGPSGN 686 Mexican tetra XP_005800738 581 FTSMATcessfS----D---------KPPSEKADTVSYYSVDTEGYY-TSMHFDCGLKGSKSFTyN-YANPGSDCGLS-- 643 southern plat... XP_005478886 651 FTSMATcessfS----D---------KPPSEKADTVSHYSVDNEGYY-TSMHFDCGLKGSRSFTyNnYAPSGTDCGLS-- 714 Nile tilapia
XP_011608506 744 TAAPYPQHITGLRAGTMTLG-RTCHSLRKPKVKPPPPKRSSSLKE-------PicgvdietdtqtEQDQPKM-ASEQEDT 814 torafugu XP_002747132 639 VFDGRAQKNQGDRSNYQDKSlSRSISLKKAKKPPLPPSRTDSLRR-------I------------PKKSSQS-NGQVLSE 698 white-tufted-... ERE84202 653 VFDGRAQRSQGDQANHQDKSlSRNISLRKAKKPPLPPCRTDSLRR-------V------------PKKNSQS-NGQMLNE 712 Chinese hamster XP_004880923 622 VFDGRAQKSQGDQSGYPDKSlPRNISLKKAKKPPLPPSRTDSLRR-------I------------PKKSGQS-NGQVLNE 681 naked mole-rat XP_006639121 741 VAPSMDGYPQQEYQGHRTTG-RQSLSFKKPKVKPAPPKRSSSLKKtssganvP------------DKKEPKI-NSGQPLP 806 spotted gar XP_006005948 706 ITSNHSECIQQNFADTGRQG-RQSISLKKPKAKPAPPKRSSSLKK-------Tdngt-----nvlDKKEPKI-NSGQHMT 771 coelacanth XP_003218915 768 VASSFTNCTWQDYVNHRRHG-KQSISLKKPKAKPAPPKRSSSLRKpdsstdlP------------EKKEPKIsSGQQHMP 834 green anole XP_007259457 687 IAPGMGEYPQPDYRGVSTLG-RQCLSLRKPKAKPPPPKRSSSLKEtsssvdvP------------EQNEPKI-TNELPLP 752 Mexican tetra XP_005800738 644 -----------DMSGHLTLG-RRCLSLRKSKAKPSPPKRSSSLRKicseghiP------------EKREPKI-TGTYRHP 698 southern plat... XP_005478886 715 -----------DSSGHMTLG-RRCLSLKKPKVKPSPPKRSSSLRKicsegniP------------VKKEPKI-TCGQQLP 769 Nile tilapia
XP_011608506 815 --LSSTDTNLELeqDLESAPEPLQTACLVAEPLGTWGMGLHETVDIVE-PMSFSSAD---------THSFKDEGAVQSDY 882 torafugu XP_002747132 699 slIATLQHSLQL--SLPGKGGSSPSQSPCSDLEEPWLPRSRSQSTVSAgSSMTSATTpnvyslcgvTPSQSDTSSVKSEY 776 white-tufted-... ERE84202 713 slIASLQHSLQQ--SLPGKGGSSPSQSPCSDFEEPWLPRSRSQSIVSEgSSMTSTTTpnvyslcgvTPSQSDTSSVKSEY 790 Chinese hamster XP_004880923 682 slIATLQQSLQL--SLPGKGGSSASQSPCSDFEEPWLPRSRSQSTVSAgSSMTSATTpnvyslcgvTPSQSDTSSLKSEY 759 naked mole-rat XP_006639121 807 --LSSREMKLQL--DLASSPGQLENPTLGDEPAEPWEVGNAGEVTd---ATLFGSTD---------NHSFKDEGAVQSDY 870 spotted gar XP_006005948 772 --PSSREIKLQL--DLSMSSGRLENSGLSSEQELLW--DNENDNEAKDdQS--SSTD---------APSFKDEGAEQSDY 834 coelacanth XP_003218915 835 --HTSREMKLPL--EFANTPSRTENANLPSKQELPW--DNQDESGLKElS--YDTMD---------IPSFKDEGAEQSHY 897 green anole XP_007259457 753 --LSSREMRLQL--DLAGSSGQLETAGLCDEPIGAW--GVENVREMLDcSSPFSSSD---------THSFKDEGAVQSDY 817 Mexican tetra XP_005800738 699 vsLSSKERRMQL--ALSGSPGLMENSSLGREPLEVWAM--EGTSDLTD-LGILSSKD---------AHSFKDNGIVQSDY 764 southern plat... XP_005478886 770 --LSAKERKLQL--AFSGSPAHTENSSLVRETRVGW--GVEGSADLPD----LVSTD---------THSFKDEGVLQSDY 830 Nile tilapia
XP_011608506 883 ADLWLHNSDLKC-NNGEYTSMSNSSTATGTTVMECMKSP-------D-------SssssteastqalskaS-------DT 940 torafugu XP_002747132 777 TDPWGYYIDYTGmQEDPGNPAGGCSASNGAPTGNGPVRH-------V-------Q---------------E-------GS 820 white-tufted-... ERE84202 791 TDPWGYYIDYTSfQEEPGNPTGGCSASSEAPTGNGPVCH-------I-------Q---------------E-------GS 834 Chinese hamster XP_004880923 760 TDPWGYYIDYTAvQEEPGDPAGCGSASSGAPTGNGPVHH-------I-------Q---------------A-------ES 803 naked mole-rat XP_006639121 871 ADLWLLN-DLK--SNDPYRSLSNSSTATGTTVIECIKSPessesqtS-------Q---------------S-------GS 918 spotted gar XP_006005948 835 ADLWLLN-DLK--SNDPYRSLSNSSTATGTTVIECTKSP-------EgsesqtsQ---------------S-------GS 882 coelacanth XP_003218915 898 ADLWLLN-DLK--SNDPYRSLSNSSTATGTTVIECIKSPessesqtS-------Q---------------S-------GS 945 green anole XP_007259457 818 ADLWLL-SDLK--SNDPYRSLSNSSTATGTTVIEFVKSP-------E-------Svett--------vcrP-------RS 865 Mexican tetra XP_005800738 765 ADLWLLN-DLK--SSDPYRSLSNSSTATGTTVIECIKSQ-------E-------S---------------S-------ES 805 southern plat... XP_005478886 831 ADLWLLN-DLK--STDPYRSLSNSSTATGTTVIECIKSQ-------D-------S---------------SesqtsqsGS 878 Nile tilapia
XP_011608506 941 -------RAASPPLPSg--DFKLGSPEKLAGLASPSSGYSSQSETPTSTLPSssaAFFPGPQSPSTGKR--KPKVPERK 1008 torafugu XP_002747132 821 -------RATMPQVPSasvKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPV---PLFLKSMSPANGKGkpKPKVPERK 889 white-tufted-e... ERE84202 835 -------RGPMPQVPGgsvKPKITSPEKSQRVTSPSSGYSSQSNTPTALTPV---PVFLKSMSPANGKGkaKPKVPERK 903 Chinese hamster XP_004880923 804 -------KAMMPQVPG---KPKVISPEKSQRVTSPSSGYSSQSNTPTALTPV---PVFLKSMSPANGKGkaKPKVPERK 869 naked mole-rat XP_006639121 919 -------RATTPSLPSvenEFKLASPEKLAGLASPSSGYSSQSETPTSSFPS---AFFPGPLSPTSGKR--KPKVPERK 985 spotted gar XP_006005948 883 -------RATSPSLPSvenEFKLASPEKMAGLASPSSGYSSQSETPTSSFPT---TFFSGPLSPSSGKR--KPKVPERK 949 coelacanth XP_003218915 946 -------RATTPSLPSvenEFKLASPEKLAGLASPSSGYSSQSETPTSSFPT---AFFSGPLSPGGSKR--KPKVPERK 1012 green anole XP_007259457 866 -------RPTSPTLPPpesDLKLGSPEKLAGLASPSSGYSSQSETPTSSFPS---AFFPGPLSPNTGKR--KPKVPERK 932 Mexican tetra XP_005800738 806 qtsqsgsRATTPSLPSvesEFKLTSPEKLAGLASPSSGYSSQSETPTSSFPS---TFFPGPLSPATGKR--KPKVPERK 879 southern platy... XP_005478886 879 -------RATTPSLPSvegDFKLTSPEKLASLASPSSGYSSQSETPTSSFPS---TFFPGPLSPSSGKR--KPKVPERK 945 Nile tilapia
Jiyao W et al.(2023). "The conserved domain database in 2023.",