Conserved Protein Domain Family
PTCRA
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pfam15028: PTCRA (this model, PSSM-Id:291687 is obsolete and has been replaced by 464455)
Pre-T-cell antigen receptor
The pre-T-cell antigen receptor (pre-TCR), expressed by immature thymocytes, has a pivotal role in early T-cell development, including TCR beta-selection, survival and proliferation of CD4(-)CD8(-) double-negative thymocytes, and subsequent alpha/beta T-cell lineage differentiation. This protein contains an immunoglobulin domain.
Links
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Statistics
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PSSM-Id: 291687
Aligned: 7 rows
Threshold Bit Score: 185.059
Created: 24-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q0VCS0        31 GMGSTPFPSLAPPITLLVDGKQQTLVVCLVLDVAPPGFESPIWFSAGNGSSLDAFTYGPSPAEDGTWTRLAQLSLYSEEL 110 cattle
P0C6B3        20 GIAGTPFPSLAPPVTLLVDGRRHTLVVCLVLDAAPPGLDSLVWFSGGNGSALDAFTYGPSPAPDGTWTSLGQLSLSSEEL 99  Norway rat
XP_003266305  20 GVGGTLFPSLAPPIMLLVDGKQQMVVVCLVLDVAPPGFDNPIWFSAGNGSALDAFTYGPSPATDGTWTNLAHLSLPSEEL 99  northern white-...
XP_008261488  20 GVGHTPFPSLAPPITLLVDGRRQTLVVCMVLDVAPPDPASPIWFSAGNGSAVDAFTYGPSLAMDGTWTSVAQLSLPSEEL 99  rabbit
XP_004739939  40 GVGGTPFPSLAPPITLLVDGKQQTLVVCLVLNVAPPGFGGPIWFSAGNGSSLDAFTYGPSPEADGTWTSLAQLSLPSEEL 119 domestic ferret
XP_013012044  20 GAVTAAFPSLAPPVTLLVAGQRRTLVVCLVLDVAAPGPDSPVWFSAGNGSALDAFTYGPAPGTDGTWTALAQLSLPAEDS 99  domestic guinea...
XP_012404550  20 GMCTAPFPSMAPPLTQVVDGQQKTLVICLVLDISPSFADGSIWFSSGNGTTLDAFTYGPSPAGDGTWSSLAQLSLPAEEL 99  Tasmanian devil

Q0VCS0       111 AAWDTLVCHTGPGAGDHGQSTQPLQL-SG--DASSARTCLWEPLRGTRAL 157 cattle
P0C6B3       100 EAWEPLVCHTRPAAGGLNRSTHPLQL-SGe-EASTDRTCPQETLRGTQRQ 147 Norway rat
XP_003266305 100 ASWEPLVCHTRPGAEGHSRSTQPLQL-SG--EASTARTCPREPLSGTPSG 146 northern white-cheeked gibbon
XP_008261488 100 ASWEPLVCHTGPRTGGRSRSTQPLQL-SG--EASPARRCPQEPPRGMAAQ 146 rabbit
XP_004739939 120 AAWENLVCHTGPEAGNRSQSTQPLQL-SG--EASSARTCLWERLRGTRGQ 166 domestic ferret
XP_013012044 100 AAWESLVCHAEPGPGSPRRSTQPLRLaAGg-RVLAGIRCPGSPhpawhag 148 domestic guinea pig
XP_012404550 100 ASWEPLVCHTGPGWQPQGPSTRPLQL-SGepKAEKCQQELTTGPYGL-SQ 147 Tasmanian devil
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