Conserved Protein Domain Family
zf-CCHC_3
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pfam13917: zf-CCHC_3 (this model, PSSM-Id:290628 is obsolete and has been replaced by 404753)
Zinc knuckle
The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.
Links
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Statistics
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PSSM-Id: 290628
Aligned: 21 rows
Threshold Bit Score: 41.9971
Created: 30-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q7QJY9        11 ENVRAACKKCGFPGHLTYQCRnyltvdpqsqA--------Vvp---vqKRPGSESPEQNY-L 60  Anopheles gambiae str. PEST
Q4R5Z6        39 NKQHVRCQKCLEFGHWTYECT----------Gkr----kyL-------HRPSRTAELKKA-L 78  crab-eating macaque
A0E2U0        31 DAAAVRCQRCLKYGHLTYECK----------Nen----vyL-------YRPSRTMQFKEK-Q 70  Paramecium tetraurelia
Q57US0        21 SNAKKTCQKCGSKAHWTFECKgv------tpSrg----aaT-------TRLSRTQQLRWG-I 64  Trypanosoma brucei
Q4D9Y6        21 SGASRVCQKCASTEHWTFECQna------adAtr----ktT-------ARLSRSQMLRWG-I 64  Trypanosoma cruzi
XP_001844226 102 FPKGVRCQKCLEFGHWSYECK----------Gkr----kyV-------HRSSRTQLLKKN-L 141 southern house mosquito
KFH08460     236 AIYNIACQRCGGKGHMAHECY----------Ntgg--nkyEmleeerpARPEHTAVIQPK-F 284 Toxoplasma gondii MAS
XP_001564660  18 TNASKRCQTCSSKEHWTFECPqrqvstssakKsa----aaT-------VKLSRSQMLRYG-I 67  Leishmania braziliensis MHOM/BR/7...
XP_002676901  17 EGGGGFCQKCFTEGHWTYQCK----------GekapsttyT-------KRLSHTEKLEMM-R 60  Naegleria gruberi strain NEG-M
XP_001696858  27 NRQQARCQRCLQIGHYTYECK----------Nea----ayA-------ARPSRTQQLKQGrF 67  Chlamydomonas reinhardtii
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