Conserved Protein Domain Family
Axin_b-cat_bind
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pfam08833: Axin_b-cat_bind (this model, PSSM-Id:285982 is obsolete and has been replaced by 462616)
Axin beta-catenin binding domain
This domain is found on the scaffolding protein Axin which is a component of the beta-catenin destruction complex. It competes with the tumour suppressor adenomatous polyposis coli protein (APC) for binding to beta-catenin.
Links
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Statistics
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PSSM-Id: 285982
Aligned: 8 rows
Threshold Bit Score: 46.4508
Created: 27-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q7PYV4       452 DDNDQDILDQHVSRV-WS---DLTPSRSPGTMspcppnmigSRSRRHELASFGG 501 Anopheles gambiae str. PEST
Q17FL7       459 DDSDQDILDKHVSRV-WS---DLTPSRSPGTMspc---pniSRARRHEVGGFGG 505 yellow fever mosquito
NP_001079086 383 EDDPQSILDDHVSRV-LKtpaNLSPRSQSPFV---------QRKGKFQPAFSKG 426 African clawed frog
XP_011611148 507 DDDPESILDEHVQRV-MKtpgCQSPGATNSTL---------GGGGRHSPPKSSR 550 torafugu
XP_003371974 539 pEDAEAILDDYYNRVgWKdspKQSPMRSPGFA---------FGSRKKSPGSKSP 583 Trichinella spiralis
XP_002056137 486 EDNDQDILDQHVSRV-WK---DQTPHRSPGTMspcppipsrRRTATHDSGMVSD 535 Drosophila virilis
XP_011188092 438 EDNDQDILDQHVSRV-WK---DQTPHRSPGTMspcpplptrRRTITHDSGMLSD 487 melon fly
CDS34199     695 DN-AQAILEDHCSRI-WDtsaDRTPTSSSGS----------GGNGTHLQQVSSD 736 Hymenolepis microstoma
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