4UM8,3G9W


Conserved Protein Domain Family
Integrin_b_cyt
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pfam08725: Integrin_b_cyt (this model, PSSM-Id:285884 is obsolete and has been replaced by 462580)
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Integrin beta cytoplasmic domain
Integrins are a group of transmembrane proteins which function as extracellular matrix receptors and in cell adhesion. Integrins are ubiquitously expressed and are heterodimeric, each composed of an alpha and beta subunit. Several variations of the the alpha and beta subunits exist, and association of different alpha and beta subunits can have different a different binding specificity. This domain corresponds to the cytoplasmic domain of the beta subunit.
Links
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Statistics
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PSSM-Id: 285884
Aligned: 67 rows
Threshold Bit Score: 51.4063
Created: 16-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4UM8_B        733 LVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFK--NVTY 774  human
XP_009861622  369 LKTNYDKRKWEEFQAEVKKSKWTESNNPIHREAKQTFV--NPRF 410  vase tunicate
XP_004348755 1142 VHTIADRREWEKFQRDKESMRWKGDDNPLFKSSTKEFD--NPLY 1183 Capsaspora owczarzaki ATCC 30864
XP_004346743 1009 ygMLMDKREWQKFEQGRQASQWKSDNNPLFQSSVKETE--NPLY 1050 Capsaspora owczarzaki ATCC 30864
XP_011403709  257 IFVYKDHREYKNFLSEINRSKGSAQENPTYLKPIIETV--NPAY 298  Amphimedon queenslandica
XP_011403560  716 cliMKDKRELKKFQSEVNDAAWADTANPLYVTPITDYQ--NVAY 757  Amphimedon queenslandica
XP_011410117  655 iFVYRDHREYKTFLYEVNQSKRMQQENPVYLNPITETV--NPVH 696  Amphimedon queenslandica
XP_003383731  768 cfiLADRAEWKKFEKEVAETDLSKNFNPLYHSPAVKYD--NIAF 809  Amphimedon queenslandica
CBY15338      779 IICWISRMEVKEFENMRSKEALTSGNNPIYQKPETTHRtdNIVY 822  Oikopleura dioica
XP_009860486  794 YQTWRDKREWKVFENEMKKSKWTKDINPVFQKPKTRFE--NPAY 835  vase tunicate
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