1WPA


Conserved Protein Domain Family
Occludin_ELL
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pfam07303: Occludin_ELL (this model, PSSM-Id:284669 is obsolete and has been replaced by 462140)
Occludin homology domain
This domain represents a conserved region approximately 100 residues long within eukaryotic occludin proteins and the RNA polymerase II elongation factor ELL. Occludin is an integral membrane protein that localizes to tight junctions, while ELL is an elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. This shared domain is thought to mediate protein interactions.
Links
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Statistics
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PSSM-Id: 284669
Aligned: 109 rows
Threshold Bit Score: 76.7892
Created: 13-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1WPA_A         15 ITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYR-EES-EE-YMAA----ADEYNRL---KQvkgSAD 84   human
XP_006585535 1127 IRTFSQYKEYVQEFQDKYDSYCSLNKILEGYRDEFQKLGNDLEHAK-GRDmDR-YYDIveqlKESYRRC---G-----PR 1196 soybean
XP_004236392 1127 IENFAQYEEYVQEYREKYDSYCSINKILESYRNEFIKLGKELDVSKgRDT-KR-FSDMlgqlKDSYRKC---G-----PR 1196 tomato
CAN69267     1231 IKDFSQYKEYVQEYHEKYDSYNSLNKILESYRNEFHKLGKDLEVAK-GRDlER-YYNIleqlKDTYSQC--------STR 1300 wine grape
XP_006385319 1025 IKDFSQYQEYVQEYRDKYDSYCSLNRILESYRNEFHKLGKDLESAK-GRDmDR-YHNIlvqlKDSYSQC---GM-----K 1094 black cottonwood
NP_566681    1091 ISDHLQYKAYMQEYNDKYDSYHSINKILESHRNDFQKLGQDLGFAK-GRDvER-YNKIveqiKESYCKY---GE-----R 1160 thale cress
XP_006651112 1069 IKDLPQYKDYVQEYNEKYEVYSYLNSQIEKTRSEFLKIQEDLNSAK-ERD-KDlYYRIleriRDMYHES---G-----TR 1138 malo sina
XP_002468367 1098 IKDYSQYKDYVQEYNEKYGVYSYLNSQIDKTKSEFLKVQDDLNVAK-ERD-KEqYYNTverlRDMYRES---G-----AR 1167 sorghum
XP_006844919 1121 IKDDAQYKEYTKEYSEKHSCYSSLYKLLESERADFEKFRRDLEHAK-DRDmDS-YNNIveriIQSYRLC---G-----PG 1190 Amborella tri...
CCD79044      645 ISTSEQASMYLAEFECTYPTYLRMYHSFSDIWKTVSNLRSQLLEAT-RTE-GF-DSATtthlANQLDKFirrSR---SQK 718  Schistosoma m...

1WPA_A         85 YKSKKNHCKQLKSKLSHIKKMVGDY 109  human
XP_006585535 1197 HKRLKKIFVVLHTELENLKGRIKDF 1221 soybean
XP_004236392 1197 HVRLKKIFIVLHEELKHLKQMIKDF 1221 tomato
CAN69267     1301 HKRLKKIFVVLHEELKNLKQRIKDY 1325 wine grape
XP_006385319 1095 HRRLKKIFIVLHKELEQLKQRIKDF 1119 black cottonwood
NP_566681    1161 HKRLKKVFVVLHEELKHLKQRMRDY 1185 thale cress
XP_006651112 1139 HKLMKKVFGLLHEELQTIKRRIKDF 1163 malo sina
XP_002468367 1168 HKLMKKVFILLHEELQIIKQRIKDF 1192 sorghum
XP_006844919 1191 HIRMKKVFIVLHKELQLLRQRIEEY 1215 Amborella trichopoda
CCD79044      719 YRDDEIQLTLMVHKLRLLKQRLAvs 743  Schistosoma mansoni
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