pfam05326: SVA (this model, PSSM-Id:283081 is obsolete and has been replaced by 398804)
Seminal vesicle autoantigen (SVA)
This family consists of seminal vesicle autoantigen and prolactin-inducible (PIP) proteins. Seminal vesicle autoantigen (SVA) is specifically present in the seminal plasma of mice. This 19-kDa secretory glycoprotein suppresses the motility of spermatozoa by interacting with phospholipid. PIP, has several known functions. In saliva, this protein plays a role in host defence by binding to microorganizms such as Streptococcus. PIP is an aspartyl proteinase and it acts as a factor capable of suppressing T-cell apoptosis through its interaction with CD4.
Jiyao W et al.(2023). "The conserved domain database in 2023.",