1O67


Conserved Protein Domain Family
MOSC
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pfam03473: MOSC (this model, PSSM-Id:281471 is obsolete and has been replaced by 460936)
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MOSC domain
The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes. These MOSC domains contain an absolutely conserved cysteine and occur either as stand-alone forms, or fused to other domains such as NifS-like catalytic domain in Molybdenum cofactor sulfurase. The MOSC domain is predicted to be a sulfur-carrier domain that receives sulfur abstracted by the pyridoxal phosphate-dependent NifS-like enzymes, on its conserved cysteine, and delivers it for the formation of diverse sulfur-metal clusters.
Links
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Statistics
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PSSM-Id: 281471
Aligned: 369 rows
Threshold Bit Score: 44.1389
Created: 25-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1O67_C        56 QAEKKVHGGPDRALCHYPREHYLYW-----AREFpeqa---elfvAPAFGENLSTdgl--------teSNVYX------- 112 Escherichia coli
Q2U121       285 gTPSVHGYTDQQPININSLSSVHAV-----STLLpken---qplnAFRFRANLWItgapaf--deeswKRYRIlpkgpda 354 Aspergillus oryzae
Q0VMX2        33 dRHYRRNAKPEEQITLIESEAIDSFnreyqQQVV-----------PSTLRRNVLT-------------KGVDLna----l 84  Alcanivorax bor...
XP_002506624  40 EGTYVAFQEPGRQLTLISKESAEAHlagvaRGQVs----------VGNLRRNVVVsgms------ardLEDAI------- 96  Micromonas sp. ...
BAL27393      59 HCAASGRGGGKRQLSLIQAEHLVAIaalvgRDEVd----------PALLRRNLVVsglnllaartlfrDQPLV------- 121 Azoarcus sp. KH32C
WP_011763752  51 HRTSGGRGGGKRQVTLIQAEHLPVIaalvgRDALd----------PALLRRNLVVsginlhaarslfdDQALV------- 113 Azoarcus sp. BH72
EMF13724     284 DQDYRVGFPDAFPIHIMNMASIRDI-----DASLpeetatkgrldARRFRANIYVsgpday--tedrwKRIAI------- 349 Sphaerulina mus...
XP_007679309 226 gnDFRVGFGDAFPVNLMGLASVKAI-----DDSLpsdtsakgqldPTRFRANFYItgtapf--tedtwKKITV------- 291 Baudoinia compn...
EQB51721     285 gTPSVHGYTDQQPVNLNSLSSVHAV-----SALLppen---qpldALRFRANIWItgapaf--aeeswKRYRIlpkavsd 354 Colletotrichum ...
CCT72482     279 gkPAIHGYTDQQPVNVNSLASVHAV-----SALLpken---qplnALRFRANIWIkgapaf--deetwKRYRVvpkqqda 348 Fusarium fujiku...

1O67_C       113 -GDI--------------FRWGEali----------------------qvsQPRS-PCYKLNYhFd-----iSDIAQLXQ 149 Escherichia coli
Q2U121       355 gPRAdva---------ptVSVVCrtsrctmpnvdpetgkpstdnpppekkrGKPQ-PSATLVK-F-------RRVEDGNK 416 Aspergillus oryzae
Q0VMX2        85 eGRE--------------FQLGnirl----------------------rgiELCE-PCSVVGQlLagd-ltpKQVINALL 126 Alcanivorax bor...
XP_002506624  97 -GCV--------------LMLGdacr---------------------vrvhRLCV-PCLYNEKlNq-----aPGLMEAVW 134 Micromonas sp. ...
BAL27393     122 ------------------LRIGaevv---------------------leltGVCE-PCSRMEDvLgpggynaMR------ 155 Azoarcus sp. KH32C
WP_011763752 114 ------------------LRIGevvl----------------------evtGPCD-PCSRMEAvLgpgaynaMR------ 146 Azoarcus sp. BH72
EMF13724     350 -GNTasengr--qsipakFHAACrtarcqlp------------nvdpltgiKDRHePATTLTR-T-------RQVDEGAK 406 Sphaerulina mus...
XP_007679309 292 -GRRigrndkglfecdaeYHVACrtarcklp------------nvdqdtgvKDRNePYTTLSK-T-------RKVDTGAY 350 Baudoinia compn...
EQB51721     355 eKRAeva---------pkLSVVCrtsrctmpnvnletgtfeadipvagkkkGKPQ-PSATLIE-H-------RTVETGNP 416 Colletotrichum ...
CCT72482     349 aSPS--------------LSVVCrtsrctlpnvnpltgkfdtdnphgdrtrGNAQ-PSSTLVK-H-------RTVEDGNP 405 Fusarium fujiku...

1O67_C       150 NT-GKVGWLYSVIAPG-----------KVSADAPLE 173 Escherichia coli
Q2U121       417 SAlGYIGMHCVPEDRAlrmaeeqekglYVAVGDEIE 452 Aspergillus oryzae
Q0VMX2       127 ---GRGGLRCEILSSG-----------VVRVGDNIE 148 Alcanivorax borkumensis SK2
XP_002506624 135 ---SEAGVNCEILAGG-----------SLKVGDVVK 156 Micromonas sp. RCC299
BAL27393     156 ---GHGGVVARVLIGG-----------VLRIGDAVV 177 Azoarcus sp. KH32C
WP_011763752 147 ---GHGGMTARVLVGG-----------PLRVGDVVR 168 Azoarcus sp. BH72
EMF13724     407 PH-PCLGLSIIPMFERg----------VVRIGDEVT 431 Sphaerulina musiva SO2202
XP_007679309 351 PH-PCLGMQTIPMFERg----------IIRVGDEVQ 375 Baudoinia compniacensis UAMH 10762
EQB51721     417 SAlGYIGMHCVPEDQDleeakeqraglYVEVGDEIE 452 Colletotrichum gloeosporioides Cg-14
CCT72482     406 RAlGYLGMHCVPENAGlqqatdsveslYVQVGDEIE 441 Fusarium fujikuroi IMI 58289
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