Conserved Protein Domain Family
R3H_DEXH_helicase
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cd06007: R3H_DEXH_helicase 
R3H domain of a group of proteins which also contain a DEXH-box helicase domain, and may function as ATP-dependent DNA or RNA helicases. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
Links
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Statistics
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PSSM-Id: 100077
Aligned: 12 rows
Threshold Bit Score: 95.4579
Created: 27-Feb-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Download Cn3D
 
RxxxH motif
Feature 1:RxxxH motif
Evidence:
  • Comment:The RxxxH motif gives R3H domain its name.
  • Citation:PMID 9787637
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                       #   #                         
BAE98834       22 RIWATKVIEDFRASg-nEVYTFEHnLSNNERGVIHQMCRKMgIQSKSSGRGEQRRLSIFK 80   thale cress
BAD53327       48 LVRVSKVLEDFQASd-aQVYKFEPgISKQERAAIHEMCRKMgMISKSSGNGERRCLSVYK 106  Japanese rice
NP_073739      46 KIAVNIALERFRYGd-qREMEFPSsLTSTERAFIHRLSQSLgLVSKSKGKGANRYLTVKK 104  human
AAI21455       38 KIAVNIALERFRYSd-qKEMEFPSsLTSTERAFIHRLAQSLgLVSKSKGKGPNRCLTLKK 96   western clawed frog
XP_413970      57 EIALNLALERFWYSd-dQEMSFPSsFTSTERAFIHRLCQSLgLISKSKGKGSSRYLTVRK 115  chicken
XP_001632393   22 KIAVKIALDKFRYDetqKELEFPSsFTAVERAYIHRLCLNLgLKSRSRGKGSNRFLSVSN 81   starlet sea anemone
NP_172152      18 GAWATKVLEDFRASg-nDSYVFEQqLTNSERGIIHQMCRTMgLRSKSNGSGEERRLSLFK 76   thale cress
XP_001763578   32 RISIVDRLNQFKASn-eEELIFEAdLSNHDRAVVHDTCKKLgLKSKSRGYGDDRRVAVFK 90   Physcomitrella patens subsp. patens
CAO69972       38 RIRISRALQEFRETh-nEVYTFEAnLTNHERAVVHEVCRKMgMTSKSSGRGSQRRVSVYK 96   wine grape
CAL52525       25 RIDIAKALEDFRADpnaSELEFPPnVDNHFRAVVHAECKKLgLKSKSHGKGDDRRVRVTK 84   Ostreococcus tauri
XP_783600      23 KISVDLAIQEFRHDeseTVLEFPAsFSNNERAYIHRLAISCgLKSKSKGKGSNRYLTLIK 82   purple urchin
EDS38478       20 RIAIHYMIDKFVQDeklNEFDFPVsFTREHRAYIHDYVKNKsLKSRSHGKGNQRYLTIYK 79   southern house mosquito

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